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CY1114238T1 - 2,4 – δι (φαινυλαμινο) - πυριμιδινες χρησιμες στην αντιμετωπιση των νεοπλασματικων παθησεων, των φλεγμονωδων διαταραχων και των διαταραχων του ανοσοποιητικου συστηματος - Google Patents

2,4 – δι (φαινυλαμινο) - πυριμιδινες χρησιμες στην αντιμετωπιση των νεοπλασματικων παθησεων, των φλεγμονωδων διαταραχων και των διαταραχων του ανοσοποιητικου συστηματος

Info

Publication number
CY1114238T1
CY1114238T1 CY20131100414T CY131100414T CY1114238T1 CY 1114238 T1 CY1114238 T1 CY 1114238T1 CY 20131100414 T CY20131100414 T CY 20131100414T CY 131100414 T CY131100414 T CY 131100414T CY 1114238 T1 CY1114238 T1 CY 1114238T1
Authority
CY
Cyprus
Prior art keywords
disorders
treatment
fenylamino
inflammatory
neoplastic
Prior art date
Application number
CY20131100414T
Other languages
English (en)
Inventor
Carlos Garcia-Echeverria
Takanori Kanazawa
Eiji Kawahara
Keiichi Masuya
Naoko Matsuura
Takahiro Miyake
Osamu Ohmori
Ichiro Umemura
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32995437&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1114238(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0319227A external-priority patent/GB0319227D0/en
Priority claimed from GB0322370A external-priority patent/GB0322370D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CY1114238T1 publication Critical patent/CY1114238T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48—Two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Νέα παράγωγα πυριμιδίνης του τύπου (I), διεργασίες για την παραγωγή τους, η χρήση τους ως αναστολείς IGF-1R και ALK στην αντιμετώπιση των νεοπλασματικών ασθενειών, των φλεγμονωδών διαταραχών και των διαταραχών του ανοσοποιητικού συστήματος και σε φαρμακευτικές συνθέσεις που τα περιλαμβάνουν.
CY20131100414T 2003-03-14 2013-05-27 2,4 – δι (φαινυλαμινο) - πυριμιδινες χρησιμες στην αντιμετωπιση των νεοπλασματικων παθησεων, των φλεγμονωδων διαταραχων και των διαταραχων του ανοσοποιητικου συστηματος CY1114238T1 (el)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0305929.2A GB0305929D0 (en) 2003-03-14 2003-03-14 Organic compounds
GB0319227A GB0319227D0 (en) 2003-08-15 2003-08-15 Organic compounds
GB0322370A GB0322370D0 (en) 2003-09-24 2003-09-24 Organic compounds
EP10009414A EP2275413B1 (en) 2003-03-14 2004-03-12 2,4-di(phenylamino)-pyrimidines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders

Publications (1)

Publication Number Publication Date
CY1114238T1 true CY1114238T1 (el) 2016-08-31

Family

ID=32995437

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100414T CY1114238T1 (el) 2003-03-14 2013-05-27 2,4 – δι (φαινυλαμινο) - πυριμιδινες χρησιμες στην αντιμετωπιση των νεοπλασματικων παθησεων, των φλεγμονωδων διαταραχων και των διαταραχων του ανοσοποιητικου συστηματος

Country Status (26)

Country Link
US (2) US7964592B2 (el)
EP (2) EP1606265B1 (el)
JP (1) JP4796487B2 (el)
KR (1) KR101148261B1 (el)
CN (2) CN101921236B (el)
AT (1) ATE497495T1 (el)
AU (1) AU2004220338B2 (el)
BR (2) BRPI0408347B8 (el)
CA (1) CA2518932C (el)
CY (1) CY1114238T1 (el)
DE (1) DE602004031287D1 (el)
DK (1) DK2275413T3 (el)
EC (1) ECSP056019A (el)
ES (1) ES2409885T3 (el)
GB (1) GB0305929D0 (el)
IL (1) IL170546A (el)
IS (1) IS2961B (el)
MA (1) MA27668A1 (el)
MX (1) MXPA05009883A (el)
NO (1) NO331977B1 (el)
NZ (1) NZ542219A (el)
PL (2) PL1606265T3 (el)
PT (2) PT1606265E (el)
SI (1) SI2275413T1 (el)
TN (1) TNSN05225A1 (el)
WO (1) WO2004080980A1 (el)

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