CY1110954T1 - Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφες - Google Patents
Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφεςInfo
- Publication number
- CY1110954T1 CY1110954T1 CY20101101079T CY101101079T CY1110954T1 CY 1110954 T1 CY1110954 T1 CY 1110954T1 CY 20101101079 T CY20101101079 T CY 20101101079T CY 101101079 T CY101101079 T CY 101101079T CY 1110954 T1 CY1110954 T1 CY 1110954T1
- Authority
- CY
- Cyprus
- Prior art keywords
- semi
- solid
- pharmaceutical forms
- formulations
- mucosal adhesives
- Prior art date
Links
- 239000007787 solid Substances 0.000 title abstract 2
- 239000000853 adhesive Substances 0.000 title 1
- 230000001070 adhesive effect Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 241001465754 Metazoa Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Inorganic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Adhesive Tapes (AREA)
Abstract
Η εφεύρεση σχετίζεται με ημιστερεές βλεννοκολλώδεις φαρμακοτεχνικές μορφές για κολπική χρήση, που έχουν βελτιωμένα τεχνικά και οργανοληπτικά χαρακτηριστικά. Οι φαρμακοτεχνικές μορφές της εφεύρεσης περιέχουν τουλάχιστον δύο βιοκολλώδη πολυμερή που σχηματίζουν πηκτή και ένα ενεργό συστατικό. Οι αναφερθείσες φαρμακοτεχνικές μορφές μπορούν να χρησιμοποιηθούν για να αποτρέψουν και/ή να θεραπεύσουν διάφορες παθολογικές καταστάσεις και διαταραχές σε ανθρώπους και ζώα.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES200301672A ES2237298B1 (es) | 2003-07-16 | 2003-07-16 | Formulaciones mucoadhesivas semisolidas. |
EP04742064A EP1652535B1 (en) | 2003-07-16 | 2004-07-16 | Semi-solid mucoadhesive formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1110954T1 true CY1110954T1 (el) | 2015-06-11 |
Family
ID=34072910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20101101079T CY1110954T1 (el) | 2003-07-16 | 2010-11-25 | Ημιστερεες βλεννοκολλωδεις φαρμακοτεχνικες μορφες |
Country Status (13)
Country | Link |
---|---|
US (1) | US8663688B2 (el) |
EP (2) | EP1652535B1 (el) |
JP (1) | JP4891765B2 (el) |
AT (1) | ATE482723T1 (el) |
CY (1) | CY1110954T1 (el) |
DE (1) | DE602004029369D1 (el) |
DK (1) | DK1652535T3 (el) |
ES (2) | ES2237298B1 (el) |
HR (1) | HRP20100635T1 (el) |
PL (1) | PL1652535T3 (el) |
PT (1) | PT1652535E (el) |
SI (1) | SI1652535T1 (el) |
WO (1) | WO2005007194A1 (el) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
BRPI0414500A (pt) | 2003-09-19 | 2006-11-07 | Drugtech Corp | formulação farmacêutica composição para tratar uma infecção vaginal, e, métodos para tratar uma infecção vaginal, para estabilizar uma formulação de clindamicina, para tratar ou prevenir uma recorrência de uma infecção vaginal em uma paciente e para tratar condições vaginais |
CA2612415A1 (en) * | 2005-06-16 | 2006-12-28 | Warner Chilcott Company, Inc. | Estrogen compositions for vaginal administration |
CN101232869B (zh) * | 2005-06-16 | 2016-03-02 | 沃纳奇尔科特有限责任公司 | 局部给药的凝胶组合物 |
CA2612380C (en) * | 2005-06-16 | 2017-06-06 | Warner Chilcott Company, Inc. | Estrogen compositions for vaginal administration |
CN101351188A (zh) * | 2005-08-12 | 2009-01-21 | 药物技术公司 | 雌激素组合物和应用它们的治疗方法 |
KR20090031847A (ko) * | 2006-01-20 | 2009-03-30 | 피어 트리 파머슈티칼스 인코포레이티드 | 위축성 질염을 치료하는 방법 |
RS56044B1 (sr) * | 2006-05-12 | 2017-09-29 | Christian Noe | Primena kombinovanih preparata koji sadrže antimikotike |
EP2034984A4 (en) | 2006-06-02 | 2013-03-06 | Pear Tree Women S Health Care | PROCESS FOR TREATING ATROPHIC VAGINITIS |
WO2008005783A2 (en) * | 2006-06-30 | 2008-01-10 | Drugtech Corporation | Treatment of non- infectious inflammatory vulvovaginitis with a bioadhesive clindamycin composition |
ES2310968B1 (es) * | 2007-06-25 | 2010-02-08 | Italfarmaco, S.A. | Uso de estriol en bajas dosis. |
ES2344673B1 (es) * | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
NZ590878A (en) * | 2008-08-12 | 2013-01-25 | Novabay Pharmaceuticals Inc | Antimicrobial gel formulations comprising an halogenated amine compound dispersed in a poly(acrylic acid) water-swellable polymer |
BRPI0803568B8 (pt) * | 2008-08-14 | 2021-05-25 | Biolab San Us Farm Ltda | composição mucoaderente |
ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
PT2552487T (pt) * | 2010-04-01 | 2016-12-30 | Pharmanest Ab | Composições anestésicas termogelificantes |
CN102293735B (zh) * | 2011-08-19 | 2013-05-01 | 辽宁万嘉医药科技有限公司 | 一种抗真菌咪唑类药物缓释凝胶和制备方法 |
PL2782584T3 (pl) | 2011-11-23 | 2021-12-13 | Therapeuticsmd, Inc. | Naturalne skojarzone hormonalne formulacje i terapie zastępcze |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
CN102600288B (zh) * | 2012-04-20 | 2014-03-05 | 广西源安堂药业有限公司 | 一种治疗阴道炎的复方黄松凝胶药物及其制备方法 |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10045935B2 (en) | 2012-07-31 | 2018-08-14 | Egis Pharmaceuticals Plc | Transdermal formulation containing COX inhibitors |
KR101358993B1 (ko) | 2012-09-05 | 2014-02-06 | 임혜선 | 네일 프린팅용 트랜스퍼 솔루션 및 이를 이용한 네일 프린팅 방법 |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
KR20170005819A (ko) | 2014-05-22 | 2017-01-16 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 천연 복합 호르몬 대체 제형 및 요법 |
BR112016029338A2 (pt) | 2014-07-29 | 2017-08-22 | Therapeuticsmd Inc | creme transdérmico |
US20160175271A1 (en) * | 2014-12-19 | 2016-06-23 | Gavis Pharmaceuticals | Rectal suppository for ulcerative colitis |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
CN108712901A (zh) * | 2016-01-07 | 2018-10-26 | 维拉玛尔有限公司 | 用于经皮递送以使角质层和血清中的药物浓度最大化的凝胶组合物及其使用方法 |
RU2018133932A (ru) | 2016-04-01 | 2020-05-12 | Терапьютиксмд, Инк. | Фармацевтическая композиция стероидного гормона |
WO2017173044A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd Inc. | Steroid hormone compositions in medium chain oils |
AU2019365255A1 (en) | 2018-10-26 | 2021-06-03 | Viramal Limited | Mucoadhesive gel composition |
EP3659583B1 (en) | 2018-11-30 | 2023-06-07 | Viramal Limited | A method of preparing a gelling agent, the gelling agent obtained thereby, and the use of said gelling agent |
CN110151680A (zh) * | 2019-04-10 | 2019-08-23 | 重庆医药高等专科学校 | 雌三醇凝胶产品及制备方法 |
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JPH0830004B2 (ja) | 1983-11-14 | 1996-03-27 | コロンビア ラボラトリーズ インコーポレイテッド | 生物接着性組成物およびそれにより治療する方法 |
NZ222698A (en) | 1987-01-08 | 1990-02-26 | Squibb & Sons Inc | Bioadhesive suppository formulations comprising a medicament, water, a hydrocolloid and low melting point base |
US5719197A (en) * | 1988-03-04 | 1998-02-17 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
DE69014081T2 (de) | 1989-10-31 | 1995-03-30 | Columbia Laboratories, Inc., Miami, Fla. | Mittel zur Feuchthaltung vaginalen Gewebes. |
JP2510052B2 (ja) | 1989-10-31 | 1996-06-26 | コロンビア ラボラトリーズ インコーポレイテッド | 組織与湿組成物及び方法 |
US5543150A (en) * | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
US5667492A (en) | 1994-10-07 | 1997-09-16 | Columbia Laboratories, Inc. | Use and composition of an anti-sexually transmitted diseases formulation |
AT408067B (de) * | 1995-03-17 | 2001-08-27 | Gebro Pharma Gmbh | Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung |
US5741525A (en) | 1995-10-24 | 1998-04-21 | Marshall University Research Corporation | Vaginal pharmaceutical hydrogen peroxide composition |
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IT1284874B1 (it) | 1996-08-02 | 1998-05-22 | Farmigea Spa | Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici |
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WO1998020872A1 (en) | 1996-11-14 | 1998-05-22 | Halldor Thormar | Topical formulations containing as a therapeutic active agent fatty acids or fatty alcohols or monoglyceride derivatives thereof for treating of mucosa infections |
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US6159491A (en) | 1999-02-12 | 2000-12-12 | Biovector Technologies, Inc. | Prolonged release bioadhesive vaginal gel dosage form |
CA2366688A1 (en) | 1999-02-26 | 2000-08-31 | Chiron Corporation | Use of bioadhesives and adjuvants for the mucosal delivery of antigens |
SE522260C2 (sv) | 1999-10-01 | 2004-01-27 | Ericsson Telefon Ab L M | Metod, system och säkerhetsadapter för att exekvera säker dataöverföring i ett trådlöst nät |
UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
ATE350011T1 (de) * | 1999-10-22 | 2007-01-15 | Lif Hlaup Ehf Bio Gels Pharmac | Pharmazeutische zusammensetzung zur behandlung von ulzerationen und/oder erosionen des schleimhautepithels |
JP2004505931A (ja) | 2000-08-03 | 2004-02-26 | アンタレス ファルマ アイピーエル アクチェンゲゼルシャフト | 適切な治療水準を保証する活性化合物の経皮投与及び/又は経粘膜投与のための新規組成物 |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
US7709026B2 (en) * | 2001-10-29 | 2010-05-04 | Columbia Laboratories, Inc. | Low concentration of peroxide for treating or preventing vaginal infections |
US6967194B1 (en) * | 2002-09-18 | 2005-11-22 | Susan Matsuo | Bio-identical hormones and method of use |
ES2237298B1 (es) | 2003-07-16 | 2006-11-01 | Italfarmaco, S.A. | Formulaciones mucoadhesivas semisolidas. |
-
2003
- 2003-07-16 ES ES200301672A patent/ES2237298B1/es not_active Expired - Fee Related
-
2004
- 2004-07-16 DE DE602004029369T patent/DE602004029369D1/de not_active Expired - Lifetime
- 2004-07-16 DK DK04742064.1T patent/DK1652535T3/da active
- 2004-07-16 US US10/565,062 patent/US8663688B2/en active Active
- 2004-07-16 EP EP04742064A patent/EP1652535B1/en not_active Expired - Lifetime
- 2004-07-16 JP JP2006519939A patent/JP4891765B2/ja not_active Expired - Lifetime
- 2004-07-16 PT PT04742064T patent/PT1652535E/pt unknown
- 2004-07-16 PL PL04742064T patent/PL1652535T3/pl unknown
- 2004-07-16 EP EP09161078A patent/EP2100612A3/en not_active Withdrawn
- 2004-07-16 AT AT04742064T patent/ATE482723T1/de active
- 2004-07-16 WO PCT/ES2004/000336 patent/WO2005007194A1/es active Application Filing
- 2004-07-16 SI SI200431522T patent/SI1652535T1/sl unknown
- 2004-07-16 ES ES04742064T patent/ES2353694T3/es not_active Expired - Lifetime
-
2010
- 2010-11-24 HR HR20100635T patent/HRP20100635T1/hr unknown
- 2010-11-25 CY CY20101101079T patent/CY1110954T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2237298B1 (es) | 2006-11-01 |
JP2007528864A (ja) | 2007-10-18 |
ATE482723T1 (de) | 2010-10-15 |
EP2100612A2 (en) | 2009-09-16 |
ES2237298A1 (es) | 2005-07-16 |
SI1652535T1 (sl) | 2010-12-31 |
PL1652535T3 (pl) | 2011-03-31 |
ES2353694T3 (es) | 2011-03-04 |
JP4891765B2 (ja) | 2012-03-07 |
US20060240111A1 (en) | 2006-10-26 |
DE602004029369D1 (de) | 2010-11-11 |
EP1652535B1 (en) | 2010-09-29 |
WO2005007194A1 (es) | 2005-01-27 |
US8663688B2 (en) | 2014-03-04 |
EP2100612A3 (en) | 2010-06-02 |
EP1652535A1 (en) | 2006-05-03 |
HRP20100635T1 (hr) | 2010-12-31 |
PT1652535E (pt) | 2010-11-18 |
DK1652535T3 (da) | 2010-11-15 |
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