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CY1109069T1 - Ενωσεις ιμιδαζοπυριδαζινης - Google Patents

Ενωσεις ιμιδαζοπυριδαζινης

Info

Publication number
CY1109069T1
CY1109069T1 CY20091100529T CY091100529T CY1109069T1 CY 1109069 T1 CY1109069 T1 CY 1109069T1 CY 20091100529 T CY20091100529 T CY 20091100529T CY 091100529 T CY091100529 T CY 091100529T CY 1109069 T1 CY1109069 T1 CY 1109069T1
Authority
CY
Cyprus
Prior art keywords
compounds
pyridasin
imimaza
crf1
formula
Prior art date
Application number
CY20091100529T
Other languages
English (en)
Inventor
Heather Janelle Barbosa
Elizabeth Aaron Collins
Chafiq Hamdouchi
Erik James Hembre
Philip Arthur Hipskind
Richard Duane Johnston
Jianliang Lu
Michael John Rupp
Takako Takakuwa
Richard Craig Thompson
Original Assignee
Eli Lilly And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Company filed Critical Eli Lilly And Company
Publication of CY1109069T1 publication Critical patent/CY1109069T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
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    • A61P31/18—Antivirals for RNA viruses for HIV
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    • A—HUMAN NECESSITIES
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    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Virology (AREA)
  • AIDS & HIV (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Transplantation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)

Abstract

Η παρούσα εφεύρεση σχετίζεται με νέες ενώσεις υποκατεστημένης ιμιδαζο[1,2-b]πυριδαζίνης του τύπου (I), φαρμακευτικές συνθέσεις αυτών, και τη χρήση τέτοιων ενώσεων ως ανταγωνιστών υποδοχέα του παράγοντα ελευθέρωσης κορτικοτροπίνης 1 (CRF1) στην αγωγή ψυχιατρικών διαταραχών και νευρολογικών νόσων.
CY20091100529T 2005-03-21 2009-05-18 Ενωσεις ιμιδαζοπυριδαζινης CY1109069T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66381605P 2005-03-21 2005-03-21
EP06738924A EP1869049B1 (en) 2005-03-21 2006-03-20 Imidazopyridazine compounds

Publications (1)

Publication Number Publication Date
CY1109069T1 true CY1109069T1 (el) 2014-07-02

Family

ID=36753943

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091100529T CY1109069T1 (el) 2005-03-21 2009-05-18 Ενωσεις ιμιδαζοπυριδαζινης

Country Status (25)

Country Link
US (1) US7612067B2 (el)
EP (1) EP1869049B1 (el)
JP (1) JP4971300B2 (el)
KR (1) KR20070120963A (el)
CN (1) CN101142217B (el)
AT (1) ATE424402T1 (el)
AU (1) AU2006227300B2 (el)
BR (1) BRPI0608857A2 (el)
CA (1) CA2600478C (el)
CR (1) CR9389A (el)
CY (1) CY1109069T1 (el)
DE (1) DE602006005477D1 (el)
DK (1) DK1869049T3 (el)
EA (1) EA012393B1 (el)
ES (1) ES2321446T3 (el)
IL (1) IL185014A0 (el)
MA (1) MA29437B1 (el)
MX (1) MX2007011600A (el)
NO (1) NO20074961L (el)
PL (1) PL1869049T3 (el)
PT (1) PT1869049E (el)
SI (1) SI1869049T1 (el)
TN (1) TNSN07358A1 (el)
WO (1) WO2006102194A1 (el)
ZA (1) ZA200706715B (el)

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