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CR9930A - Compuestos - Google Patents

Compuestos

Info

Publication number
CR9930A
CR9930A CR9930A CR9930A CR9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A CR 9930 A CR9930 A CR 9930A
Authority
CR
Costa Rica
Prior art keywords
compounds
antibacterials
compounds containing
containing tricyclic
tricyclic nitrogen
Prior art date
Application number
CR9930A
Other languages
English (en)
Spanish (es)
Inventor
Nathalie Cailleau
David Thomas Davies
Joel Michael Esken
Alan Joseph Hennessy
Sukumar Senthil Kumar Kusalakumari
Roger Edward Markwell
Timothy James Miles
Neil David Pearson
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of CR9930A publication Critical patent/CR9930A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CR9930A 2005-10-21 2008-04-25 Compuestos CR9930A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US72897505P 2005-10-21 2005-10-21
US82659006P 2006-09-22 2006-09-22

Publications (1)

Publication Number Publication Date
CR9930A true CR9930A (es) 2008-07-29

Family

ID=38256822

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9930A CR9930A (es) 2005-10-21 2008-04-25 Compuestos

Country Status (27)

Country Link
US (2) US20080221110A1 (fr)
EP (1) EP1954697B1 (fr)
JP (1) JP2009512695A (fr)
KR (1) KR20080064173A (fr)
AR (1) AR057981A1 (fr)
AT (1) ATE458737T1 (fr)
AU (1) AU2006335042A1 (fr)
BR (1) BRPI0617467A2 (fr)
CA (1) CA2626641A1 (fr)
CR (1) CR9930A (fr)
CY (1) CY1110137T1 (fr)
DE (1) DE602006012535D1 (fr)
DK (1) DK1954697T3 (fr)
EA (1) EA200801128A1 (fr)
ES (1) ES2340531T3 (fr)
HK (1) HK1118546A1 (fr)
HR (1) HRP20100194T8 (fr)
IL (1) IL190803A0 (fr)
MA (1) MA29873B1 (fr)
NO (1) NO20082191L (fr)
NZ (1) NZ567315A (fr)
PE (1) PE20070793A1 (fr)
PL (1) PL1954697T3 (fr)
PT (1) PT1954697E (fr)
SI (1) SI1954697T1 (fr)
TW (1) TW200736263A (fr)
WO (1) WO2007081597A2 (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1954697T3 (da) * 2005-10-21 2010-06-14 Glaxo Group Ltd Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler
EP1963324B1 (fr) * 2005-12-22 2010-04-21 Glaxo Group Limited Composes heterocycliques, leur synthese et leur utilisation en tant qu'antibacteriens
ATE481406T1 (de) 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
GB0608263D0 (en) 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
CL2008001002A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
DK2137196T3 (da) 2007-04-20 2011-01-10 Glaxo Group Ltd Tricykliske nitrogenholdige forbindelser som antibakterielle midler
EP2005995A1 (fr) * 2007-06-22 2008-12-24 Glaxo Group Limited Composés hétérocycliques pour le traitement de la tuberculose
EP2080761A1 (fr) 2008-01-18 2009-07-22 Glaxo Group Limited Composés
RU2010138648A (ru) 2008-02-20 2012-03-27 Актелион Фармасьютиклз Лтд (Ch) Азатрициклические соединения антибиотиков
TW200944529A (en) 2008-04-15 2009-11-01 Actelion Pharmaceuticals Ltd Tricyclic antibiotics
RU2011108008A (ru) 2008-08-04 2012-09-10 Актелион Фармасьютиклз Лтд (Ch) Производные трициклического алкиламинометилоксазолидинона
MY158520A (en) 2008-10-07 2016-10-14 Actelion Pharmaceuticals Ltd Tricyclic oxazolidinone antibiotic compounds
US20110275661A1 (en) 2008-10-17 2011-11-10 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
BRPI0924081A2 (pt) 2008-12-12 2018-03-20 Actelion Pharmaceuticals Ltd DERIVADOS DE 5- AMINO -2-(1-hIDROXI-ETIL)- TETRAHIDROPIRANO.
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
TW201313726A (zh) 2011-09-16 2013-04-01 Actelion Pharmaceuticals Ltd 製造合成之中間體之方法
US9029368B2 (en) 2011-11-30 2015-05-12 Actelion Pharmaceuticals Ltd. 3,7-disubstituted octahydro-2H-pyrido[4,3-E][1,3]oxazin-2-one antibiotics
WO2016027249A1 (fr) 2014-08-22 2016-02-25 Glaxosmithkline Intellectual Property Development Limited Composés contenant de l'azote tricyclique pour le traitement de l'infection à neisseria gonorrhoeae
EP3590341A4 (fr) 2017-02-28 2021-03-10 Mitsui Chemicals Agro, Inc. Composition de prévention de maladies des plantes et procédé de prévention de maladies des plantes l'utilisant
WO2018207023A2 (fr) * 2017-05-10 2018-11-15 Albajuna Therapeutics, S.L. Dérivés de protéine de fusion fc présentant une double activité élevée immunomodulatrice et antivirale contre le vih
JP2023506147A (ja) 2019-12-02 2023-02-15 ストーム・セラピューティクス・リミテッド Mettl3阻害剤としてのポリヘテロ環式化合物
SMT202400488T1 (it) 2019-12-06 2025-01-14 Vertex Pharma Tetraidrofurani sostituiti come modulatori dei canali del sodio

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3323868A (en) * 1961-12-14 1967-06-06 Laporte Chemical Manufacture of hydrogen peroxide
NL294427A (fr) * 1962-06-23
GB1394373A (en) * 1972-05-17 1975-05-14 Pfizer Ltd Control of plant diseases
US4066706A (en) * 1975-04-21 1978-01-03 Halcon International, Inc. Preparation of ethylbenzene hydroperoxide
DE2805915C3 (de) * 1978-02-13 1981-11-05 Dynamit Nobel Ag, 5210 Troisdorf Reaktor zur Oxidation von Gemischen aus p-Xylol und p-Toluylsäuremethylester mit sauerstoffhaltigen Gasen in flüssiger Phase
DE2914218C2 (de) * 1978-04-12 1985-10-24 Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo N-Acylderivate des Ampicillins und Amoxicillins, Verfahren zu deren Herstellung und pharmazeutische Zubereitungen, welche die Verbindungen enthalten
US4416884A (en) * 1978-04-12 1983-11-22 Otsuka Pharmaceutical Co., Ltd. Piperazinylbenzoheterocyclic compounds
NO156828C (no) * 1980-11-10 1987-12-02 Otsuka Pharma Co Ltd Analogifremgangsm te for fremstilling av antibakterielt virksomme benzoheterocykliske forbindelser.
ATE21514T1 (de) * 1982-03-25 1986-09-15 Ciba Geigy Ag Verfahren zur herstellung von 1,2,5,6-tetrahydro4h-pyrrolo(3,2,1-ij)-chinolin-4-on und neue 5ch820325
US4595755A (en) * 1982-03-25 1986-06-17 Ciba-Geigy Corporation 5-halo-1,2,3-(1,2-dihydropyrrolo)-4-quinolones
US4603199A (en) * 1982-10-25 1986-07-29 Riker Laboratories, Inc. Phenyl-substituted tricyclic antibacterial agent intermediates
US4443447A (en) * 1982-10-25 1984-04-17 Riker Laboratories, Inc. Phenyl-substituted tricyclic antibacterial agents
US6121285A (en) * 1995-11-22 2000-09-19 Daiichi Pharmaceutical Co., Ltd. Substituted aminocycloalkylpyrrolidine derivatives and cis-substituted aminocycloalkylpyrrolidine derivatives
GB9622386D0 (en) * 1996-10-28 1997-01-08 Sandoz Ltd Organic compounds
JPH11222407A (ja) * 1997-11-14 1999-08-17 Sankyo Co Ltd 新規殺菌剤
US7825121B2 (en) * 1999-05-04 2010-11-02 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
US6289745B1 (en) * 1999-05-04 2001-09-18 James Bowers High temperature insertion type flow element and mounting extension
US6391865B1 (en) * 1999-05-04 2002-05-21 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
US6689765B2 (en) * 1999-05-04 2004-02-10 Schering Corporation Piperazine derivatives useful as CCR5 antagonists
GB0101577D0 (en) * 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
UY27192A1 (es) * 2001-03-01 2002-09-30 Smithkline Beecham Corp Inhibidores de peptido-deformilasa
GB0112836D0 (en) * 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
US7109213B2 (en) * 2002-01-29 2006-09-19 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
AR040336A1 (es) * 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
PA8577501A1 (es) * 2002-07-25 2004-02-07 Warner Lambert Co Inhibidores de quinasas
TW200427688A (en) * 2002-12-18 2004-12-16 Glaxo Group Ltd Antibacterial agents
PT1675852E (pt) * 2003-09-22 2009-03-25 Janssen Pharmaceutica Nv Quinolonas e naftiridonas heterocíclicas de 7-aminoalquilidenilo
US7691850B2 (en) * 2004-06-15 2010-04-06 Glaxo Group Limited Antibacterial agents
EP1773831A1 (fr) * 2004-07-08 2007-04-18 Glaxo Group Limited Agents antibacteriens
US7732612B2 (en) * 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
EP1900732A4 (fr) * 2005-06-24 2009-11-18 Toyama Chemical Co Ltd Nouveau composé hétérocyclique azoté et sel de celui-ci
GB0521563D0 (en) * 2005-10-21 2005-11-30 Glaxo Group Ltd Novel compounds
DE102005050892A1 (de) * 2005-10-21 2007-04-26 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ausgewählte CGRP-Antagonisten, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel
DK1954697T3 (da) * 2005-10-21 2010-06-14 Glaxo Group Ltd Peri-kondenserede tricykliske forbindelser, der er anvendelige som antibakterielle midler
EP1963324B1 (fr) * 2005-12-22 2010-04-21 Glaxo Group Limited Composes heterocycliques, leur synthese et leur utilisation en tant qu'antibacteriens
ATE481406T1 (de) * 2006-04-06 2010-10-15 Glaxo Group Ltd Pyrrolochinoxalinonderivate als antibakterielle mittel
GB0608263D0 (en) * 2006-04-26 2006-06-07 Glaxo Group Ltd Compounds
SG164384A1 (en) * 2006-05-26 2010-09-29 Toyama Chemical Co Ltd Novel heterocyclic compound or salt thereof and intermediate thereof
GB0613208D0 (en) * 2006-07-03 2006-08-09 Glaxo Group Ltd Compounds
EP1992628A1 (fr) * 2007-05-18 2008-11-19 Glaxo Group Limited Dérivés et analogues de N-éthylquinolones et N-éthylazaquinolones
GB0705672D0 (en) * 2007-03-23 2007-05-02 Glaxo Group Ltd Compounds
EP1980251A1 (fr) * 2007-04-13 2008-10-15 Glaxo Group Limited Derivées de pyrrolo[3,2,1-ij]quinoline-4-one pour traiter la tuberculose
GB0707708D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
GB0707706D0 (en) * 2007-04-20 2007-05-30 Glaxo Group Ltd Compounds
DK2137196T3 (da) * 2007-04-20 2011-01-10 Glaxo Group Ltd Tricykliske nitrogenholdige forbindelser som antibakterielle midler

Also Published As

Publication number Publication date
PT1954697E (pt) 2010-05-17
MA29873B1 (fr) 2008-10-03
ATE458737T1 (de) 2010-03-15
DK1954697T3 (da) 2010-06-14
IL190803A0 (en) 2008-12-29
DE602006012535D1 (de) 2010-04-08
JP2009512695A (ja) 2009-03-26
EP1954697B1 (fr) 2010-02-24
AR057981A1 (es) 2008-01-09
SI1954697T1 (sl) 2010-05-31
CA2626641A1 (fr) 2007-07-19
HK1118546A1 (en) 2009-02-13
ES2340531T3 (es) 2010-06-04
EA200801128A1 (ru) 2008-10-30
PL1954697T3 (pl) 2010-07-30
US20080280892A1 (en) 2008-11-13
PE20070793A1 (es) 2007-08-23
TW200736263A (en) 2007-10-01
NZ567315A (en) 2011-01-28
WO2007081597A2 (fr) 2007-07-19
NO20082191L (no) 2008-07-16
KR20080064173A (ko) 2008-07-08
CY1110137T1 (el) 2015-01-14
AU2006335042A1 (en) 2007-07-19
HRP20100194T1 (hr) 2010-05-31
US20080221110A1 (en) 2008-09-11
WO2007081597A3 (fr) 2008-06-12
HRP20100194T8 (en) 2010-06-30
BRPI0617467A2 (pt) 2011-07-26
EP1954697A2 (fr) 2008-08-13

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal (granting procedure)