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CO2023000493A2 - Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, y producción y usos de estos - Google Patents

Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, y producción y usos de estos

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Publication number
CO2023000493A2
CO2023000493A2 CONC2023/0000493A CO2023000493A CO2023000493A2 CO 2023000493 A2 CO2023000493 A2 CO 2023000493A2 CO 2023000493 A CO2023000493 A CO 2023000493A CO 2023000493 A2 CO2023000493 A2 CO 2023000493A2
Authority
CO
Colombia
Prior art keywords
viral vectors
immunogenic compositions
production
influenza hemagglutinin
vectors expressing
Prior art date
Application number
CONC2023/0000493A
Other languages
English (en)
Inventor
Teshome Mebatsion
Aemro Kassa
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of CO2023000493A2 publication Critical patent/CO2023000493A2/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
    • A61K39/17—Newcastle disease virus
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/255—Marek's disease virus
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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Abstract

[00540] La invención se relaciona con vectores virales recombinantes y composiciones que incluyen los mismos para usar como vehículos para inducir una respuesta inmunológica. Los vectores virales multivalentes se pueden usar en composiciones o vacunas que contienen uno o más vectores virales recombinantes para la protección contra una variedad de patógenos. Además, la presente invención se relaciona con la formación de estos vectores virales puede incluir la inserción y expresión de genes extraños para la protección contra una variedad de patógenos. Se proveen además métodos de elaboración y uso de vectores virales recombinantes, así como composiciones inmunogénicas que incluyen los vectores y/o antígenos. En particular, las composiciones inmunogénicas pueden incluir vectores virales recombinantes, tales como vHVT509, vHVT522 y/o vHVT523.
CONC2023/0000493A 2020-06-17 2023-01-16 Vectores de hvt recombinantes que expresan hemaglutinina de influenza y composiciones inmunogénicas, y producción y usos de estos CO2023000493A2 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202063040411P 2020-06-17 2020-06-17
PCT/US2021/037631 WO2021257706A1 (en) 2020-06-17 2021-06-16 Recombinant hvt vectors expressing influenza hemagglutinin and immunogenic compositions, and production and uses thereof

Publications (1)

Publication Number Publication Date
CO2023000493A2 true CO2023000493A2 (es) 2023-01-26

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TW202214863A (zh) 2022-04-16
WO2021257706A1 (en) 2021-12-23
AR122653A1 (es) 2022-09-28
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CA3186579A1 (en) 2021-12-23
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