CN2881624Y - Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information - Google Patents
Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information Download PDFInfo
- Publication number
- CN2881624Y CN2881624Y CN 200620000212 CN200620000212U CN2881624Y CN 2881624 Y CN2881624 Y CN 2881624Y CN 200620000212 CN200620000212 CN 200620000212 CN 200620000212 U CN200620000212 U CN 200620000212U CN 2881624 Y CN2881624 Y CN 2881624Y
- Authority
- CN
- China
- Prior art keywords
- detected
- thing
- human body
- micro
- little
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Landscapes
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
本实用新型是一种具有同时检测多种人体生理信息的微信道生物传感器试片，尤指一种具有多个微信道的生物传感器试片结构，借由人体体液(如血液)以检测各种生理信息，该试片上设有多个微信道，可利用毛细扩散现象将人体体液导入与微信道相连接的不同生物反应酵素区内，分别与置放于所述的生物反应酵素区内的不同反应酵素作用，并可依次或同时进行多种待检测物，如血糖(Glucose)、胆固醇总量(Totalcholesterol)、高密度脂蛋白胆固醇(High density lipoprotein)、尿酸(Uricacid)……等生化物质含量的检测。
The utility model is a micro-channel biosensor test strip capable of simultaneously detecting a variety of human physiological information, and in particular, a biosensor test strip structure having a plurality of micro-channels, which detects various physiological information by means of human body fluids (such as blood). The test strip is provided with a plurality of micro-channels, and can utilize the capillary diffusion phenomenon to introduce human body fluids into different bioreaction enzyme areas connected to the micro-channels, and respectively react with different reaction enzymes placed in the bioreaction enzyme areas, and can sequentially or simultaneously perform detection of a variety of objects to be detected, such as blood sugar (Glucose), total cholesterol (Totalcholesterol), high-density lipoprotein cholesterol (High density lipoprotein), uric acid (Uricacid) ... and other biochemical substances.
Description
Technical field
The utility model is a kind of little channel biological sensor chip that detects multiple human body physiologic information simultaneously that has, especially refer to a kind of biological sensor chip structure with a plurality of little channels, by human body fluid (as blood) to detect various physiologic informations, this test piece is provided with a plurality of little channels, can utilize the capillary diffusion phenomena human body fluid to be imported in the different biological respinse ferment district that is connected with little channel, respectively with the differential responses ferment effect that is placed in the described biological respinse ferment district, and can be successively or carry out the detection of multiple thing biochemical substances content to be detected simultaneously.
Background technology
In recent years, during along with the flourishing of economy and enjoyment modern civilization, some modern civilization diseases (also being commonly called as chronic disease), as diabetes, hypertension, hyperlipemia, gout ... therefore also approaching our life, health of people is being constituted a serious threat, except that the control of strengthening noting self diet, suitable motion, also need regularly do health detection, allow the health status that the user can understanding itself to medical institutes.Along with the idea of nursing at home promotes day by day, fast, the house oneself's measurement product that cheaply, does not need the professional to operate day by day increases, for example: the mechanical, electrical sub-ear thermometer of blood sugar, electronic type blood pressure meter, cholesterol measure device ... Deng, need not expend time in and money special trip goes to the medical space just can measure by medical personnel's assistance, and need only see through owned medical measuring instrument, can grasp self health whenever and wherever possible, with the state of an illness that avoids delay; More owing to diabetes, vascular hypertension, hyperlipemia, gout illness ... be all closely bound uply, and join and take place, so the user often needs to detect through multiple project, could the complete grasp state of an illness.
Please refer to shown in Figure 1, the detection of aforesaid general chronic disease is analyzed by blood mostly, the user need partly take a blood sample in finger or ear-lobe in advance, and blood is inserted the opening 101 of the electrode test piece 100 of biology sensor, these opening 101 places are provided with reaction ferment 102 districts that can be made for usefulness, different reaction ferment only can be for a kind of detection of physiologic information, and the electrode test piece 100 of known biology sensor is by a tabular electrical isolation base material, normally adopt to have electrical insulation characteristics and heat-resistant quality, so that the processing that is heating and curing of biological respinse film and conductive layer.For example PC plate, PVC plate, PP plate, glass mat, bakelite plate, ceramic wafer or glass plate etc.Wherein conductive layer comprises the electrode signal circuit 103 of pair of separated, one is the working electrode signal line, one is the reference electrode signal line, this electrode signal circuit one end is connected to reaction ferment district 102, the other end of electrode signal circuit then is connected to electric chemical formula biosensing apparatus (not shown), so can detect physiologic information in the blood by electrochemical reaction; Each time, the detection of each project promptly needs through blood collection procedure, blood collection procedure each time promptly is to represent pain one time, especially long-term chronic sufferer, the all necessary pain that constantly repeats for years, because a kind of biological information of human body, as: blood sugar, because of only having single confession thing to be detected, its electrode test piece 100 inserts opening 101 and single biological respinse ferment, so, if the tester desires to know other biological information of human body such as cholesterol total amount, HDL-C, LDL-C, or uric acid ... equal size, then must go blood sampling again, and use different electrode test pieces and biosensing apparatus to detect.
Summary of the invention
The utility model is for reducing the number of times and the pain of user's blood sampling, detect and can have simultaneously polynary project concurrently, special thing opening part to be detected in the biological sensor electrode test piece is provided with one and has a plurality of little channels, utilize the capillary diffusion phenomena that the blood in the thing opening to be detected is directed into different ferment reaction zones respectively, in each different ferment reaction zone, then provide corresponding reaction ferment, therefore can in one-time detection, record the detected value of multiple biological information of human body simultaneously.
The utility model is achieved in that a kind of little channel biological sensor chip that detects multiple human body physiologic information simultaneously that has, in order to detect the content of thing mesophytization material to be detected, it is characterized in that this biological sensor chip comprises: the substrate of a tool electrical insulating property; One cover plate, this cover plate be relative with substrate and fit together, and an end limit is provided with a thing to be detected and inserts opening; One thing to be detected is inserted the disposal area, and this thing to be detected inserts the disposal area and to insert opening relative with thing to be detected; One has a plurality of little channels that are connected, and an end of this little channel is inserted the disposal area with this thing to be detected and is connected, and the other end then is connected with each reaction ferment district respectively; More than one work, reference electrode, this work, reference electrode are attached on the substrate, and the one end is connected with reaction ferment district, and the other end extends to the distolateral of this test piece, detects more than one biological information of human body simultaneously.
Thus, the beneficial effects of the utility model are: can be by a plurality of little channels, utilize the capillary diffusion phenomena that the blood in the determinand opening is sent to different ferment reaction zones respectively, can in one-time detection, record the detected value of multiple biological information of human body simultaneously, more economical efficient detection is provided.
Description of drawings
Fig. 1 is the electrode test piece synoptic diagram of known biology sensor
Fig. 2 is the first embodiment synoptic diagram of the present utility model
Fig. 3 is the decomposing schematic representation of first embodiment of the present utility model
Fig. 4 is another embodiment synoptic diagram of the present utility model
Fig. 5 is the cut-open view of another embodiment of the present utility model
Fig. 6 is a user mode synoptic diagram of the present utility model
Symbol description:
The 3rd reaction ferment district 133, the second reaction ferment district 132
The 4th reaction ferment district 134 cover plates 17
18 first pairs of work of substrate, reference electrode 19
The second pair of work, the 3rd pair of work of reference electrode 192, reference electrode 193
The 4th pair of work, reference electrode 194 human-body biological signal transducers 20
Embodiment
At first, see also shown in Fig. 2,3, wherein Fig. 2 is the synoptic diagram of first embodiment of the present utility model, and Fig. 3 is the decomposing schematic representation of first embodiment.Present embodiment is to be example can detect four kinds of biological information of human body simultaneously, the detection zone of disparity items can be set according to actual demand during use, the utlity model has the electrode test piece 10 of the little channel biological sensor chip structure that detects multiple human body physiologic information simultaneously, comprise a cover plate 17; What one side of this cover plate 17 was provided with a thing to be detected inserts opening 11; This thing to be detected is inserted opening 11 belows and is inserted thing disposal area 14 corresponding to a thing to be detected, and this thing to be detected is inserted thing disposal area 14 and connected a little channel 12, and these little channel 12 1 ends are provided with one first reaction ferment district 13; Be to be connected to the second reaction ferment district 132, the 3rd reaction ferment district 133 and the 4th reaction ferment district 134 gradually in this each interchannel again; Wherein the first reaction ferment district 13, the second reaction ferment district 132, the 3rd reaction ferment district 133 and the 4th reaction ferment district 134 can comply with the difference of the reaction ferment of being put and separate and be blood sugar ferment reaction zone, cholesterol total amount ferment reaction zone, HDL-C ferment reaction zone or uric acid reaction zone etc.One substrate 18, this substrate 18 is the flat board of a tool electrical isolation, and is provided with first pair of work, reference electrode 19, the second pair of work, reference electrode 192, the 3rd pair of work, reference electrode 193 and the 4th pair of work, reference electrode 194 in this substrate 18; This first reaction ferment district 13 is connected in first pair of work, reference electrode 19, and this second reaction ferment district 132 is connected in second pair of work, reference electrode the 192, the 3rd and reacts that ferment district 133 is connected in the 3rd pair of work, reference electrode 193 and the 4th reacts ferment district 134 and is connected in the 4th pair of work, reference electrode 194; So as to the electrochemical reaction in the first reaction ferment district 13, the second reaction ferment district 132, the 3rd reaction ferment district 133 and the 4th reaction ferment district 134, spread out of via first pair of work, reference electrode 19, second pair of work, reference electrode 192, the 3rd pair of work, reference electrode 193 and the 4th pair of work, reference electrode 194.
See also shown in Fig. 4,5, Fig. 4 is the synoptic diagram of another embodiment of the present utility model, Fig. 5 is the cut-open view of another embodiment of the present utility model, this embodiment is to be example with three-dimensional galvanochemistry test piece, and wherein this first reaction ferment district 13 and first pair of work, reference electrode 19, second react the one side that ferment district 132 and second pair of work, reference electrode 192 are located at substrate 18; The 3rd reaction ferment district 133 and the 3rd pair of work, reference electrode the 193, the 4th react the relative another side that ferment district 134 and the 4th pair of work, 194 of reference electrodes are located at substrate 18, therefore; Can dwindle the width of electrode test piece.
See also shown in Figure 6, it is the user mode synoptic diagram that little channel biological sensor chip 10 of the present utility model is read thing biochemical substances content to be detected via human-body biological signal transducer 20, after the tester inserts human-body biological signal transducers 20 with this electrode test piece 10, insert thing to be detected again, can show relevant biological information of human body such as blood sugar, cholesterol total amount, HDL-C or uric acid after thing to be detected after testing by the calculation process of human-body biological signal transducer 20 ... or the like.
In sum, the utility model can be by a plurality of little channels, utilize the capillary diffusion phenomena that the blood in the determinand opening is sent to different ferment reaction zones respectively, can in one-time detection, record the detected value of multiple biological information of human body simultaneously, more economical efficient detection is provided.
Comprehensively the above only is the preferred embodiment that the utility model used, and is not in order to limit the scope that the utility model is implemented.Be all, be all the utility model claim and contain according to impartial for it variation of the utility model claim institute and modification.
Claims (4)
1, a kind of have a little channel biological sensor chip that detects multiple human body physiologic information simultaneously,, it is characterized in that this biological sensor chip comprises in order to detect the content of thing mesophytization material to be detected:
The substrate of one tool electrical insulating property;
One cover plate, this cover plate be relative with substrate and fit together, and an end limit is provided with a thing to be detected and inserts opening;
One thing to be detected is inserted the disposal area, and this thing to be detected inserts the disposal area and to insert opening relative with thing to be detected;
One has a plurality of little channels that are connected, and an end of this little channel is inserted the disposal area with this thing to be detected and is connected, and the other end then is connected with each reaction ferment district respectively;
More than one work, reference electrode, this work, reference electrode are attached on the substrate, and the one end is connected with reaction ferment district, and the other end extends to the distolateral of this test piece, detects more than one biological information of human body simultaneously.
2, as claimed in claim 1 have a little channel biological sensor chip that detects multiple human body physiologic information simultaneously, it is characterized in that: this little interchannel is to each reaction ferment district with connected mode gradually.
3, as claimed in claim 1 have a little channel biological sensor chip that detects multiple human body physiologic information simultaneously, it is characterized in that: keep equidistant between this little channel and each the reaction ferment district.
4, describedly have a little channel biological sensor chip that detects multiple human body physiologic information simultaneously as claim 2 or 3, it is characterized in that: this little channel and the work that links to each other, reference electrode are distributed in the both sides of substrate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620000212 CN2881624Y (en) | 2006-01-04 | 2006-01-04 | Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200620000212 CN2881624Y (en) | 2006-01-04 | 2006-01-04 | Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN2881624Y true CN2881624Y (en) | 2007-03-21 |
Family
ID=37881468
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200620000212 Expired - Fee Related CN2881624Y (en) | 2006-01-04 | 2006-01-04 | Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN2881624Y (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103959051A (en) * | 2011-10-31 | 2014-07-30 | 喜来健迈德斯 | Multi-reaction biosensor |
| CN104749228A (en) * | 2013-12-30 | 2015-07-01 | 深圳先进技术研究院 | Test strip and method for detecting blood glucose and blood lipid simultaneously |
| DE102017208461A1 (en) | 2017-05-18 | 2018-11-22 | Diabetes.Online Ag | Multianalytmessung |
| CN111610321A (en) * | 2019-02-26 | 2020-09-01 | 聿新生物科技股份有限公司 | Test strips with multiple independent blood collection ports |
| CN114324503A (en) * | 2020-09-30 | 2022-04-12 | 泓瀚科技股份有限公司 | Inkjet biological test piece and preparation method thereof |
| CN116643034A (en) * | 2023-05-16 | 2023-08-25 | 上海太阳生物技术有限公司 | Detection card |
-
2006
- 2006-01-04 CN CN 200620000212 patent/CN2881624Y/en not_active Expired - Fee Related
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103959051A (en) * | 2011-10-31 | 2014-07-30 | 喜来健迈德斯 | Multi-reaction biosensor |
| CN104749228A (en) * | 2013-12-30 | 2015-07-01 | 深圳先进技术研究院 | Test strip and method for detecting blood glucose and blood lipid simultaneously |
| DE102017208461A1 (en) | 2017-05-18 | 2018-11-22 | Diabetes.Online Ag | Multianalytmessung |
| CN111610321A (en) * | 2019-02-26 | 2020-09-01 | 聿新生物科技股份有限公司 | Test strips with multiple independent blood collection ports |
| CN114324503A (en) * | 2020-09-30 | 2022-04-12 | 泓瀚科技股份有限公司 | Inkjet biological test piece and preparation method thereof |
| CN116643034A (en) * | 2023-05-16 | 2023-08-25 | 上海太阳生物技术有限公司 | Detection card |
| CN116643034B (en) * | 2023-05-16 | 2024-07-23 | 上海太阳生物技术有限公司 | Detection card |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2861769C (en) | Accurate analyte measurements for electrochemical test strip based on multiple discrete measurements defined by sensed physical characteristic(s) of the sample containing the analyte | |
| US6855243B2 (en) | Electrochemical test strip having a plurality of reaction chambers and methods for using the same | |
| EP1747450A1 (en) | Connector configuration for electrochemical cells and meters for use in combination therewith | |
| CN102625913A (en) | Glucose measurement method and system | |
| JP2015508900A (en) | Coplanar analysis test strip with stacked unidirectional contact pads | |
| CN2881624Y (en) | Micro-channel biosensor test piece with simultaneous detection of multiple human physiological information | |
| CN107085023A (en) | A kind of electrochemica biological sensor and preparation method thereof | |
| AU2013322547B2 (en) | System and method for determining hematocrit insensitive glucose concentration | |
| KR20080069904A (en) | Sensor chip and sensor system | |
| AU2014301074B2 (en) | Fill error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte | |
| AU2014301060A1 (en) | Transient signal error trap for an analyte measurement determined from a specified sampling time derived from a sensed physical characteristic of the sample containing the analyte | |
| CN203535003U (en) | Biosensor | |
| AU2016212154A1 (en) | Reference electrode error trap determined from a specified sampling time and a pre-determined sampling time | |
| CN1194223C (en) | Multifunctional blood detection chip | |
| EP1380837A1 (en) | Electrochemical test strip having a plurality of reaction chambers | |
| JP3120375U (en) | Microchannel sensor test piece capable of simultaneously examining various types of human physiological information | |
| KR200412556Y1 (en) | Microchannel biodetector specimens with the ability to test several types of human physiological reactions at once | |
| CN212341089U (en) | Biosensor for eliminating mutual interference of two biochemical substances detected by one-time sample injection | |
| JP7371219B2 (en) | Determination of contamination of biosensors used in analyte measurement systems | |
| US20070161102A1 (en) | Microchannel biosensor strip capable of simultaneously detecting different human physiological information | |
| KR100533229B1 (en) | Multi-layer electrochemical biosensor | |
| CN103091377B (en) | Biosensor | |
| KR100789651B1 (en) | Disposable biosensor | |
| JP3184337U (en) | Biosensor specimen | |
| KR100777776B1 (en) | Biosensor working electrode structure for reducing measurement error |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20070321 Termination date: 20130104 |