CN202182864U - Hemoglobin detection board - Google Patents
Hemoglobin detection board Download PDFInfo
- Publication number
- CN202182864U CN202182864U CN2011202748911U CN201120274891U CN202182864U CN 202182864 U CN202182864 U CN 202182864U CN 2011202748911 U CN2011202748911 U CN 2011202748911U CN 201120274891 U CN201120274891 U CN 201120274891U CN 202182864 U CN202182864 U CN 202182864U
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- China
- Prior art keywords
- haemoglobin
- check
- sample
- cover plate
- carriers
- Prior art date
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- Expired - Fee Related
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- 238000001514 detection method Methods 0.000 title abstract description 18
- 108010054147 Hemoglobins Proteins 0.000 title abstract description 4
- 102000001554 Hemoglobins Human genes 0.000 title abstract description 4
- 239000003153 chemical reaction reagent Substances 0.000 claims abstract description 33
- 238000006243 chemical reaction Methods 0.000 claims abstract description 27
- 239000007790 solid phase Substances 0.000 claims abstract description 23
- 239000000758 substrate Substances 0.000 claims abstract description 20
- 239000000969 carrier Substances 0.000 claims description 28
- 239000000463 material Substances 0.000 claims description 11
- 230000008878 coupling Effects 0.000 claims description 6
- 238000010168 coupling process Methods 0.000 claims description 6
- 238000005859 coupling reaction Methods 0.000 claims description 6
- 239000004743 Polypropylene Substances 0.000 claims description 3
- HGAZMNJKRQFZKS-UHFFFAOYSA-N chloroethene;ethenyl acetate Chemical compound ClC=C.CC(=O)OC=C HGAZMNJKRQFZKS-UHFFFAOYSA-N 0.000 claims description 3
- 239000011521 glass Substances 0.000 claims description 3
- -1 polypropylene Polymers 0.000 claims description 3
- 229920001155 polypropylene Polymers 0.000 claims description 3
- 239000008280 blood Substances 0.000 abstract description 9
- 210000004369 blood Anatomy 0.000 abstract description 9
- 238000007689 inspection Methods 0.000 abstract description 2
- 238000007781 pre-processing Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 description 10
- 239000000126 substance Substances 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 239000012528 membrane Substances 0.000 description 5
- 238000005516 engineering process Methods 0.000 description 4
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical group O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000007767 bonding agent Substances 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000002209 hydrophobic effect Effects 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 1
- 108010061951 Methemoglobin Proteins 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 150000001540 azides Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910002092 carbon dioxide Chemical group 0.000 description 1
- 239000001569 carbon dioxide Chemical group 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000013043 chemical agent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 229920006267 polyester film Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000007430 reference method Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000011309 routine diagnosis Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000003746 solid phase reaction Methods 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
The utility model discloses a hemoglobin detection board, including sample preprocessing device and solid phase reagent reaction carrier, its characterized in that sample preprocessing device is a plurality of, sets up on bearing substrate, and its inside sample carrier of fixed sample application chemical reagent, solid phase reagent reaction carrier installs on bearing cover plate, bearing substrate and bearing cover plate pass through connecting device fixed mounting. The utility model can detect the hemoglobin concentration of a plurality of people at one time, the reaction is rapid, and the accuracy and the precision are high; the repeatability is good, and the requirement of large-scale rapid inspection on hospitals and mobile blood collection vehicles is completely met.
Description
Technical field
The utility model relates to a kind of device that detects many human hemoglobins concentration simultaneously, belongs to the Medical Devices technical field, particularly a kind of haemoglobin check-out console.
Background technology
Haemoglobin is a kind of protein of being responsible for delivery oxygen in the human body, as the important substance of accomplishing oxygen and carbon dioxide exchange in the blood, is the pacing items of the activity of earning a bare living.It is the most important index of diagnosing severity of anemia clinically that haemoglobin detects, and also is the hemopathic important indicators of auxiliary diagnosis other types simultaneously.At present; The principle that detects haemoglobin clinically is generally based on cyanmethemoglobin method (HiCN method), azide methemoglobin method (H iN3 method) or lauryl sodium sulfate haemoglobin method (SLS-Hb method), and wherein the cyanmethemoglobin method is that ICSH recommends reference method.The blood analyser and the matched reagent that design based on above-mentioned principle are to use wider haemoglobin detection method clinically.
The dry chemical detection technique is the novel inspection technology that development in recent years is got up.The dry chemical detection technique is accepted by clinical labororatory with its particular performances, becomes the new force of clinical biochemical check routine and emergency treatment testing.Compare with classic method, have simple to operate, speed fast, pollute less, the result stablizes plurality of advantages such as accurate.The mode that dry chemical detects, each chemical reagent that normally will participate in reacting is wiring solution-forming in proportion, is added on the solid phase reaction carrier, after drying, can be used for Clinical detection.In the testing process, the chemical agent dissolves speed of using in the dry chemical detection method is fast, local concentration is high, reaction velocity is fast, simultaneously, can guarantee that some reagent maintain a long-term stability under solid, dry material state.
At present, the dry chemical Fast Detection Technique still belongs to emerging technology in the Clinical detection field; Use still very not extensive at home and abroad; Its main cause can only realize single individual event visual inspection survey, though detection architecture is more stable on its detection mode except the certain difficulty of technical existence; But detection efficiency is on the low side, and this also is to hinder the dry chemical detection technique to further develop and the major reason of comprehensively popularizing.
Summary of the invention
The utility model provides a kind of haemoglobin check-out console, solved the problem that multisample detects HC simultaneously, and testing result is stable, detection efficiency is high, elegant in shape, and is convenient easy-to-use.
The utility model is to realize through following technical scheme:
A kind of haemoglobin check-out console; Comprise sample pretreatment unit and solid-phase reagent reaction carriers; Said sample pretreatment unit is several, is opened on the bearing substrate, and its internal fixation is the sample carriers of point sample chemical reagent; Said solid-phase reagent reaction carriers is fixed on and carries on the cover plate, and said bearing substrate fixedly mounts through coupling arrangement with the carrying cover plate.
Said sample pretreatment unit is the slot type container, and body is embedded on the said bearing substrate.
Said sample carriers is a kind of sample carriers of thieving paper material.
Said bearing substrate is to be processed by a kind of material in tygon, PVC, polypropylene and the organic glass.Except that above-mentioned preferred material, the hydrophobic polymeric material that other hardness are high also can be used for the preparation of bearing substrate.
Above-mentioned sample pretreatment unit installs fixing sample carriers additional with it has formed the sample pretreating zone; After the whole blood of gathering inserted the sample pretreatment unit; With the sample carriers generation effect that has cured molten born of the same parents' agent, hemocytolysis is broken, the stripping haemoglobin.
The corresponding window in some and said sample pretreatment unit position is set on the said carrying cover plate.
Said solid-phase reagent reaction carriers is a kind of polymeric membrane, can select the commercially available macromolecule member material of different materials according to the test item needs, like the nitrocellulose filter in different apertures, polyester film etc.
Said each window is pasted and is covered a solid-phase reagent reaction carriers.The membrane structure of solid-phase reagent reaction carriers is separated from each other like this, and is independent mutually, can be used for the detection of a person-portion or many person-portions blood haemoglobin.
Said coupling arrangement is a cushion, and cushion has certain thickness and elasticity, and there is bonding agent on both sides, carrier substrate and carrier cover plate is carried out non-tight be connected.
Carry cover plate and solid-phase reagent reaction carriers and formed the solid-phase reagent reaction zone, haemoglobin is detected required various chemical reaction reagent predetermined fixed on the solid-phase reagent reaction carriers.
Sample carriers and solid-phase reagent reaction carriers contact under particular instrument control; Haemoglobin in the stripping of sample pretreating zone is sent to the solid-phase reagent reaction zone; In the solid-phase reagent reaction zone with the solid-phase reagent reaction carriers on chemical reagent react; Through dry sheet type fast detecting instrument,, detect the change color on the solid-phase reagent reaction carriers film and then calculate the concentration of measured object through light source and optical sensor.In the testing process, detector to photosignal gather, analysis and data processing.Chemical reaction process carries out under the detector thermostatic control automatically on the haemoglobin check-out console, has that reaction velocity is fast, a good reproducibility, accuracy, precision advantages of higher.
The beneficial effect of the utility model is: the haemoglobin check-out console is applied to the HC of fast quantification detection people whole blood sample clinically.Because product of the present invention has characteristics such as be swift in response, accuracy, precision are high, multisample detects simultaneously, many-sided requirements such as routine diagnosis, emergency treatment, the examination of blood source can be satisfied in using in the historical facts or anecdotes border.
The present invention relates to designing and developing and technology path science, reasonable of product haemoglobin check-out console, automaticity is high, and stable performance is multiple functional, elegant in shape, and is convenient easy-to-use.The testing result accuracy is high, good reproducibility, and detection speed is fast, can satisfy the needs of extensive quick test on hospitals at different levels and the mobile blood-collecting carriage fully.
Description of drawings
Fig. 1 is the structural representation of single part of haemoglobin check-out console
Fig. 2 is the structural representation of four-player part haemoglobin check-out console
Fig. 3 is that four-player part haemoglobin check-out console carries cover plate and the window synoptic diagram on it
Embodiment
Below in conjunction with accompanying drawing, the utility model is further specified.
Like Fig. 1, be the structural representation of single part of haemoglobin check-out console, comprise sample pretreatment unit 3 and solid-phase reagent reaction carriers 1; The sample pretreatment unit is several; Be equipped with one among this figure, it is opened on the bearing substrate 5, and its internal fixation is the sample carriers 4 of point sample chemical reagent; Solid-phase reagent reaction carriers 1 is installed in and carries on the cover plate 2, and bearing substrate 5 fixedly mounts through coupling arrangement 6 with carrying cover plate 2.
Wherein sample pretreatment unit 3 is slot type containers, is embedded on the bearing substrate 5.
Bearing substrate 5 is bearing substrates of being processed by a kind of material in tygon, PVC, polypropylene and the organic glass.Its hydrophobic effect is good, and material is harder, has higher carrying and supporting capacity.
Solid-phase reagent reaction carriers 1 is a membrane structure, is a kind of polymeric membrane, has the ability of high strength absorption all ingredients, solidified reagents.
Like Fig. 2, be the structural representation of four-player part haemoglobin check-out console, wherein sample pretreatment unit 3 is four, carries the whole blood of four-player part respectively.
Like Fig. 3, four-player part haemoglobin check-out console carries cover plate and the window synoptic diagram on it, carries on the cover plate 2 to be provided with some and the corresponding window 7 in sample pretreatment unit position.Each window 7 is pasted and is covered a solid-phase reagent reaction carriers 1.The membrane structure of solid-phase reagent reaction carriers is separated from each other like this, and is independent mutually, can be used for the detection of many person-portions blood haemoglobin project.
Claims (7)
1. haemoglobin check-out console; Comprise sample pretreatment unit and solid-phase reagent reaction carriers; It is characterized in that said sample pretreatment unit is several, be opened on the bearing substrate, the fixing sample carriers of point sample chemical reagent on it; Said solid-phase reagent reaction carriers is installed in and carries on the cover plate, and said bearing substrate fixedly mounts through coupling arrangement with the carrying cover plate.
2. haemoglobin check-out console as claimed in claim 1 is characterized in that said sample pretreatment unit is the slot type container, and body is embedded on the said bearing substrate.
3. haemoglobin check-out console as claimed in claim 1 is characterized in that said sample carriers is a kind of sample carriers of thieving paper material.
4. haemoglobin check-out console as claimed in claim 1 is characterized in that said bearing substrate is the bearing substrate of being processed by a kind of material in tygon, PVC, polypropylene and the organic glass.
5. haemoglobin check-out console as claimed in claim 1 is characterized in that being provided with on the said carrying cover plate the corresponding window in some and said sample pretreatment unit position.
6. like claim 1 or 5 described haemoglobin check-out consoles, it is characterized in that said each window stickup covers a solid-phase reagent reaction carriers.
7. haemoglobin check-out console as claimed in claim 1 is characterized in that said coupling arrangement is a cushion, and said carrier substrate carries out non-tight with the carrier cover plate and is connected.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011202748911U CN202182864U (en) | 2011-08-01 | 2011-08-01 | Hemoglobin detection board |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011202748911U CN202182864U (en) | 2011-08-01 | 2011-08-01 | Hemoglobin detection board |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202182864U true CN202182864U (en) | 2012-04-04 |
Family
ID=46175896
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011202748911U Expired - Fee Related CN202182864U (en) | 2011-08-01 | 2011-08-01 | Hemoglobin detection board |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202182864U (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102384906A (en) * | 2011-08-01 | 2012-03-21 | 无锡蓝德生物医药有限责任公司 | Hemoglobin test board and preparation method and application thereof |
-
2011
- 2011-08-01 CN CN2011202748911U patent/CN202182864U/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102384906A (en) * | 2011-08-01 | 2012-03-21 | 无锡蓝德生物医药有限责任公司 | Hemoglobin test board and preparation method and application thereof |
| CN102384906B (en) * | 2011-08-01 | 2016-01-20 | 无锡蓝德生物医药有限责任公司 | Hemoglobin detection plate and its preparation method and application |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: SUZHOU BESTBAY BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: WUXI LANDEA BIOLOGICAL MEDICAL CO., LTD. Effective date: 20130517 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 214000 WUXI, JIANGSU PROVINCE TO: 215123 SUZHOU, JIANGSU PROVINCE |
|
| TR01 | Transfer of patent right |
Effective date of registration: 20130517 Address after: Xinghu Street Industrial Park of Suzhou city in Jiangsu province 215123 No. 218 BioBAY room A3-425 Patentee after: Suzhou Bestbay Biological Technology Co., Ltd. Address before: Jinxi road Binhu District 214000 Jiangsu city of Wuxi province No. 100 Patentee before: Wuxi Landea Biological Medical Co., Ltd. |
|
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20120404 Termination date: 20180801 |