CN1799590A - Deer placenta soft capsule and its preparation method - Google Patents
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Abstract
The invention provides a deer placenta soft capsule and its preparing process, wherein the capsule is prepared from the following constituents (by weight proportions): deer placenta 600-700 parts, Chinese angelica root 5-10 parts, safflower 5-10 parts, motherwort 10-15 parts, dried rehmannia root 10-15 parts, white atractylodes rhizome 10-15 parts, and donkey-hide gelatin 15-25 parts.
Description
Technical field:
The present invention relates to a kind of Embryo cervi health product and manufacture method thereof, be specifically related to a kind of deer fetus capsule and manufacture method thereof.
Background technology:
The history that Embryo cervi is used as medicine is of long duration, and ancient Chinese prescription just once had relevant record, and Embryo cervi paste widespread especially is mainly used in gynopathic treatment in the good medicine of generation.In recent years, the relevant pharmaceuticals industry and the Producers of aquaculture are started with from the research and development of Embryo cervi goods and have been done a large amount of work, Jinlin Aodong Medicine Industry Groups has been arranged at present, Guang Jitang, two positive deer are group already, enterprises such as the Inner Mongol strong first deer industry group have succeeded in developing the Aodong Lutai oral liquor, deer embryo-contained tonifying cream, Guanji hall skin care deer placenta powder capsule, the Embryo cervi granule, products such as deer embryo element, they all are to adopt Chinese crude drug and Embryo cervi compatibility with nourishing and treatment function to form, has nourishing, the effect of skin care, both can treat disease and prevent disease, can be used for auxiliary treatment after being ill again.Because the said goods is the remodeling of traditional drug, processing technique is still followed traditional handicraft, has destroyed the physiologic function of the soluble protein in the Embryo cervi, phospholipid and part hormone composition thus to a great extent.
Summary of the invention:
The purpose of this invention is to provide a kind of function that has tonic, improves the body and culature, have no side effect, and manufacture method is simple, can fully keep the deer fetus capsule and the manufacture method thereof of the physiologically active ingredient of Embryo cervi.Deer fetus capsule of the present invention, it is made up of according to ratio of weight and number following component: 600~700 parts of Embryo cervi, 20~30 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini.The manufacture method of deer fetus capsule of the present invention, it is finished by following steps: a, get 600~700 parts of Embryo cervi according to ratio of weight and number and clean, it is rotten that the unhairing post processing becomes, the NaCl solution that in the Embryo cervi gruel, adds 3~6 times of weight, the concentration of NaCl solution is 5%, lixiviate 20~60min, centrifugalize then, rotating speed is 3000~5000r/min, and it is standby to get supernatant; B, the edible ethanol that in precipitate, adds 3~8 times of weight and lixiviate 50~100h, the concentration of edible ethanol is 40~60%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add the phosphate buffer solution jordaning of 3~6 times of weight, add papain by containing 100~150I.U/g albumen in the serosity, and through behind 40~55 ℃ of constant temperature hydrolysis 2~6h, be warmed up to 90~100 ℃, lixiviate 20~40min, centrifugalize then, rotating speed is 3000~5000r/min, it is standby to get supernatant; D, get 20~30 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, supernatant with gained extracts of Chinese herbal medicine and a step gained, the supernatant of the filtrate of b step gained and c step gained is that 20~40: 60~80 ratio is carried out mixing preparation according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2~1/3 of volume, be spray dried to micropowder then again; E, be that 1: 0.3~0.5 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, adds suspension and fill pelleting on adhesive tape, and drying, check, packing are made finished product.
The present invention has following beneficial effect: 1, the present invention is in conjunction with modern biochemical technology on the basis of motherland's tradition Chinese medicine theory, adopt enzymatic isolation method water-soluble with in the Embryo cervi, the liposoluble component extracts to greatest extent, effectively kept its physiologically active ingredient, zoopery shows, the biological activity of the extract of such extracting mode gained is higher, can promote the growth promoter and the metabolism of body, enhancing body's immunological function, to nervous system, cardiovascular system has good regulating action, help to recover and keep body health, especially in resisting fatigue, aspects such as human body immunity improving power obviously are better than the product that adopts traditional handicraft to make.2, the Radix Angelicae Sinensis in Embryo cervi extracting solution and the Chinese herbal medicine, Herba Leonuri, the Radix Rehmanniae, the compatible synergism of Colla Corii Asini extracting solution have extremely strong nourishing YIN and supplementing blood, the effect of regulating menstruation analgesic, especially to menoxenia, the vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominalgia with blood stasis, bleeding not during menses have splendid therapeutic efficiency.3, the compatible synergism of Flos Carthami extract in Embryo cervi extracting solution and the Chinese herbal medicine has the effect of extremely strong promoting blood circulation to restore menstrual flow, blood stasis removing pain relieving.4, the compatible synergism of Rhizoma Atractylodis Macrocephalae extracting solution in Embryo cervi extracting solution and the Chinese herbal medicine has stronger spleen invigorating spermatogenesis, stomach reinforcing, diuretic actions.5, Embryo cervi is the important pharmaceutical raw material of traditional Chinese medicine, and Embryo cervi is can breed doe through 4~5 months fetus of breeding gestation, and Embryo cervi has the spleen invigorating spermatogenesis, and emerging sun is mended fire, controls deficient tuberculosis, blood deficiency damage of essence, menoxenia, deficiency and coldness, effects such as bleeding not during menses." herbal classic is met former " goes up note to be had " deer property YANG invigorating benefit is smart, and the pure sun of its tire looses, be preferably take a tonic or nourishing food to build up one's health innocent, so must with ginseng, stilbene, river car generation helps it, and is particularly capable ".The Embryo cervi extracting solution with boil the effect that the compatible synergism of extracts of Chinese herbal medicine of gained has stronger nourishing, keeps healthy, improves the body and culature by Radix Angelicae Sinensis, Flos Carthami, Herba Leonuri, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae, Colla Corii Asini through decocting, can nourishing YIN and supplementing blood, strong The spleen is closely related to the stomach, QI invigorating is enriched blood, promoting blood circulation to restore menstrual flow, menstruction regulating and pain relieving, kidney-reinforcing Yang-strengthening, be middle-aged and elderly people, the empty many patients group's of body first-selected nutrient health particularly.6, the Deficiency and coldness of spleen and stomach person being taken 15~30 days symptoms of deer fetus capsule can have clear improvement, and only need take 1~2 every day; Menoxenia, women deficiency and coldness person are taken 30~45 days symptoms of deer fetus capsule have bigger improvement, only need take 2 every day, every day secondary, each 1; Middle-aged and elderly people and body void person are taken 1 health care amount every day, and can take for a long time, have no side effect.7, manufacture method of the present invention is simple, and operation is easy to large-scale industrial production easily, the bioavailability height of the deer fetus capsule of producing by this manufacture method, content is accurate, and every soft capsule weighs 0.5~1g, the good uniformity of raw material, and taking convenience are easy to preserve.
The specific embodiment:
The specific embodiment one: the deer fetus capsule of present embodiment, it is made up of according to ratio of weight and number following component: 600~700 parts of Embryo cervi, 20~30 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini.
The specific embodiment two: the deer fetus capsule of present embodiment, it is made up of according to ratio of weight and number following component: 650 parts of Embryo cervi, 24 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 12 parts of Herba Leonuris, 13 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini.
The specific embodiment three: the deer fetus capsule of present embodiment, it is made up of according to ratio of weight and number following component: 600 parts of Embryo cervi, 30 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 15 parts of Herba Leonuris, 10 parts in the Radix Rehmanniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Colla Corii Asini.
The specific embodiment four: the deer fetus capsule of present embodiment, it is made up of according to ratio of weight and number following component: 700 parts of Embryo cervi, 20 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 10 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 10 parts of Herba Leonuris, 15 parts in the Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts in Colla Corii Asini.
The specific embodiment five: the manufacture method of the deer fetus capsule of present embodiment, it is finished by following steps: a, get 600~700 parts of Embryo cervi according to ratio of weight and number and clean, be processed into gruel with meat grinder after the unhairing, the NaCl solution that in the Embryo cervi gruel, adds 3~6 times of weight, the concentration of NaCl solution is 5%, lixiviate 20~60min, centrifugalize then, rotating speed is 3000~5000r/min, and it is standby to get supernatant; B, the edible ethanol that in precipitate, adds 3~8 times of weight and lixiviate 50~100h, the concentration of edible ethanol is 40~60%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add phosphate buffer (pH value is 5~8) defibrination of 3~6 times of weight, add papain by containing 100~150I.U/g albumen in the serosity, and through behind 40~55 ℃ of constant temperature hydrolysis 2~6h, be warmed up to 90~100 ℃, lixiviate 20~40min, centrifugalize then, rotating speed is 3000~5000r/min, it is standby to get supernatant; D, get 20~30 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, supernatant with gained extracts of Chinese herbal medicine and a step gained, the supernatant of the filtrate of b step gained and c step gained is that 20~40: 60~80 ratio is carried out mixing preparation according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2~1/3 of volume, be spray dried to micropowder then again; E, be that 1: 0.3~0.5 ratio is made suspension according to ratio of weight and number with soybean oil and described micropowder, adhesive tape is made in the gelatin allotment, on adhesive tape, add suspension and fill pelleting, drying, shampooing ball, drier, be up to the standards, pack and make finished product.
The specific embodiment six: the manufacture method of the deer fetus capsule of present embodiment, it is finished by following steps: a, get 650 parts of Embryo cervi according to ratio of weight and number and clean, be processed into gruel with meat grinder after the unhairing, the NaCl solution that in the Embryo cervi gruel, adds 5 times of weight, the concentration of NaCl solution is 5%, lixiviate 40min, centrifugalize then, rotating speed is 4000r/min, and it is standby to get supernatant; B, add the edible ethanol and the lixiviate 70h of 6 times of weight in precipitate, the concentration of edible ethanol is 50%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add phosphate buffer (pH value the is 6) defibrination of 4 times of weight, add papain by containing 130I.U/g albumen in the serosity, and through behind 45 ℃ of constant temperature hydrolysis 5h, be warmed up to 95 ℃, lixiviate 30min, centrifugalize then, rotating speed is 4000r/min, and it is standby to get supernatant; D, get 25 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 13 parts of Herba Leonuris, 12 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, is that 30: 70 ratio is carried out mixing preparation with the supernatant of the filtrate of the supernatant of gained extracts of Chinese herbal medicine and a step gained, b step gained and c step gained according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2 of volume, be spray dried to micropowder then again; E, be that 1: 0.4 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, on adhesive tape, add suspension and fill pelleting, drying, shampooing ball, drier, be up to the standards, pack and make finished product.
The specific embodiment seven: the manufacture method of the deer fetus capsule of present embodiment, it is finished by following steps: a, get 600 parts of Embryo cervi according to ratio of weight and number and clean, be processed into gruel with meat grinder after the unhairing, the NaCl solution that in the Embryo cervi gruel, adds 3 times of weight, the concentration of NaCl solution is 5%, lixiviate 20min, centrifugalize then, rotating speed is 3000r/min, and it is standby to get supernatant; B, add the edible ethanol and the lixiviate 50h of 3 times of weight in precipitate, the concentration of edible ethanol is 40%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add phosphate buffer (pH value the is 5) defibrination of 3 times of weight, add papain by containing 100I.U/g albumen in the serosity, and through behind 40 ℃ of constant temperature hydrolysis 2h, be warmed up to 90 ℃, lixiviate 20min, centrifugalize then, rotating speed is 3000r/min, and it is standby to get supernatant; D, get 20 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 15 parts of Herba Leonuris, 15 parts in the Radix Rehmanniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, is that 20: 80 ratio is carried out mixing preparation with the supernatant of the filtrate of the supernatant of gained extracts of Chinese herbal medicine and a step gained, b step gained and c step gained according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/3 of volume, be spray dried to micropowder then again; E, be that 1: 0.3 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, on adhesive tape, add suspension and fill pelleting, drying, shampooing ball, drier, be up to the standards, pack and make finished product.
The specific embodiment eight: the manufacture method of the deer fetus capsule of present embodiment, it is finished by following steps: a, get 700 parts of Embryo cervi according to ratio of weight and number and clean, be processed into gruel with meat grinder after the unhairing, the NaCl solution that in the Embryo cervi gruel, adds 6 times of weight, the concentration of NaCl solution is 5%, lixiviate 60min, centrifugalize then, rotating speed is 5000r/min, and it is standby to get supernatant; B, add the edible ethanol and the lixiviate 100h of 8 times of weight in precipitate, the concentration of edible ethanol is 60%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add phosphate buffer (pH value the is 8) defibrination of 6 times of weight, add papain by containing 150I.U/g albumen in the serosity, and through behind 55 ℃ of constant temperature hydrolysis 6h, be warmed up to 100 ℃, lixiviate 40min, centrifugalize then, rotating speed is 5000r/min, and it is standby to get supernatant; D, get 30 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 10 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 10 parts of Herba Leonuris, 10 parts in the Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, is that 40: 60 ratio is carried out mixing preparation with the supernatant of the filtrate of the supernatant of gained extracts of Chinese herbal medicine and a step gained, b step gained and c step gained according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2 of volume, be spray dried to micropowder then again; E, be that 1: 0.5 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, on adhesive tape, add suspension and fill pelleting, drying, shampooing ball, drier, be up to the standards, pack and make finished product.
The specific embodiment nine: the manufacture method of the deer fetus capsule of present embodiment, described extracts of Chinese herbal medicine is finished by following steps: get 20~30 parts of Chinese herbal medicine according to ratio of weight and number, and 1~2h is steeped in the water logging that adds 8~15 times of Chinese herbal medicine weight, decoct 30~100min, filter, decoct 2~4 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini.
The specific embodiment ten: the manufacture method of the deer fetus capsule of present embodiment, described Chinese herbal medicine extract is finished by following steps: get 24 parts of Chinese herbal medicine according to ratio of weight and number, and 1.5h is steeped in the water logging that adds 12 times of Chinese herbal medicine weight, decoct 60min, filter, decoct 3 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 12 parts of Herba Leonuris, 13 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini.
The specific embodiment 11: the manufacture method of the deer fetus capsule of present embodiment, described Chinese herbal medicine extract is finished by following steps: get 20 parts of Chinese herbal medicine according to ratio of weight and number, and 1h is steeped in the water logging that adds 8 times of Chinese herbal medicine weight, decoct 30min, filter, decoct 2 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 5 parts of Radix Angelicae Sinensis, 10 parts on Flos Carthami, 10 parts of Herba Leonuris, 15 parts in the Radix Rehmanniae, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 25 parts in Colla Corii Asini.
The specific embodiment 12: the manufacture method of the deer fetus capsule of present embodiment, described Chinese herbal medicine extract is finished by following steps: get 30 parts of Chinese herbal medicine according to ratio of weight and number, and 2h is steeped in the water logging that adds 15 times of Chinese herbal medicine weight, decoct 100min, filter, decoct 4 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 10 parts of Radix Angelicae Sinensis, 5 parts on Flos Carthami, 15 parts of Herba Leonuris, 10 parts in the Radix Rehmanniae, 15 parts of the Rhizoma Atractylodis Macrocephalaes, 15 parts in Colla Corii Asini.
Claims (6)
1, a kind of deer fetus capsule, it is characterized in that it is made up of according to ratio of weight and number following component: 600~700 parts of Embryo cervi, 20~30 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini.
2, deer fetus capsule according to claim 1, it is characterized in that it is made up of according to ratio of weight and number following component: 650 parts of Embryo cervi, 24 parts of Chinese herbal medicine, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 12 parts of Herba Leonuris, 13 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini.
3, a kind of manufacture method of deer fetus capsule, it is characterized in that it is finished by following steps: a, get Embryo cervi according to ratio of weight and number and clean for 600~700 parts, it is rotten that the unhairing post processing becomes, the NaCl solution that in the Embryo cervi gruel, adds 3~6 times of weight, the concentration of NaCl solution is 5%, lixiviate 20~60min, centrifugalize then, rotating speed is 3000~5000r/min, and it is standby to get supernatant; B, the edible ethanol that in precipitate, adds 3~8 times of weight and lixiviate 50~100h, the concentration of edible ethanol is 40~60%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add the phosphate buffer solution jordaning of 3~6 times of weight, add papain by containing 100~150I.U/g albumen in the serosity, and through behind 40~55 ℃ of constant temperature hydrolysis 2~6h, be warmed up to 90~100 ℃, lixiviate 20~40min, centrifugalize then, rotating speed is 3000~5000r/min, it is standby to get supernatant; D, get 20~30 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, supernatant with gained extracts of Chinese herbal medicine and a step gained, the supernatant of the filtrate of b step gained and c step gained is that 20~40: 60~80 ratio is carried out mixing preparation according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2~1/3 of volume, be spray dried to micropowder then again; E, be that 1: 0.3~0.5 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, adds suspension and fill pelleting on adhesive tape, and drying, check, packing are made finished product.
4, the manufacture method of deer fetus capsule according to claim 3, it is characterized in that it is finished by following steps: a, get Embryo cervi according to ratio of weight and number and clean for 650 parts, it is rotten that the unhairing post processing becomes, the NaCl solution that in the Embryo cervi gruel, adds 5 times of weight, the concentration of NaCl solution is 5%, lixiviate 40min, centrifugalize then, rotating speed is 4000r/min, and it is standby to get supernatant; B, add the edible ethanol and the lixiviate 70h of 6 times of weight in precipitate, the concentration of edible ethanol is 50%, filters, isolates filtrate and residue, filtrate for later use; C, in residue, add the phosphate buffer solution jordaning of 4 times of weight, add papain by containing 130I.U/g albumen in the serosity, and through behind 45 ℃ of constant temperature hydrolysis 5h, be warmed up to 95 ℃, lixiviate 30min, centrifugalize then, rotating speed is 4000r/min, and it is standby to get supernatant; D, get 25 parts of Chinese herbal medicine according to ratio of weight and number, described Chinese herbal medicine is made up of according to ratio of weight and number following component: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 13 parts of Herba Leonuris, 12 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini, use the water boiling and extraction Chinese herbal medicine filtrate, is that 30: 70 ratio is carried out mixing preparation with the supernatant of the filtrate of the supernatant of gained extracts of Chinese herbal medicine and a step gained, b step gained and c step gained according to ratio of weight and number, when falling liquid film is concentrated into mixing preparation 1/2 of volume, be spray dried to micropowder then again; E, be that 1: 0.4 ratio is made suspension with soybean oil and described micropowder according to ratio of weight and number, adhesive tape is made in the gelatin allotment, adds suspension and fill pelleting on adhesive tape, and drying, check, packing are made finished product.
5, the manufacture method of deer fetus capsule according to claim 3, it is characterized in that described Chinese herbal medicine filtrate finished by following steps: get 20~30 parts of Chinese herbal medicine according to ratio of weight and number, and 1~2h is steeped in the water logging that adds 8~15 times of Chinese herbal medicine weight, decoct 30~100min, filter, decoct 2~4 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 5~10 parts of Radix Angelicae Sinensis, 5~10 parts on Flos Carthami, 10~15 parts of Herba Leonuris, 10~15 parts in the Radix Rehmanniae, 10~15 parts of the Rhizoma Atractylodis Macrocephalaes, 15~25 parts in Colla Corii Asini.
6, the manufacture method of deer fetus capsule according to claim 5, it is characterized in that described extracts of Chinese herbal medicine finished by following steps: get 24 parts of Chinese herbal medicine according to ratio of weight and number, and 1.5h is steeped in the water logging that adds 12 times of Chinese herbal medicine weight, decoct 60min, filter, decoct 3 times, collect filtrate and obtain extracts of Chinese herbal medicine; Described Chinese herbal medicine is formed by following component and according to ratio of weight and number: 7 parts of Radix Angelicae Sinensis, 8 parts on Flos Carthami, 12 parts of Herba Leonuris, 13 parts in the Radix Rehmanniae, 13 parts of the Rhizoma Atractylodis Macrocephalaes, 20 parts in Colla Corii Asini.
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- 2004-12-30 CN CNA2004100441890A patent/CN1799590A/en active Pending
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