CN1473577A - Process for preparing special preparation for curing beriberi and smelly foot - Google Patents
Process for preparing special preparation for curing beriberi and smelly foot Download PDFInfo
- Publication number
- CN1473577A CN1473577A CNA021254230A CN02125423A CN1473577A CN 1473577 A CN1473577 A CN 1473577A CN A021254230 A CNA021254230 A CN A021254230A CN 02125423 A CN02125423 A CN 02125423A CN 1473577 A CN1473577 A CN 1473577A
- Authority
- CN
- China
- Prior art keywords
- present
- preparation
- herbal medicine
- chinese herbal
- beriberi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 206010047601 Vitamin B1 deficiency Diseases 0.000 title claims abstract description 7
- 208000002894 beriberi Diseases 0.000 title claims abstract description 7
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000003814 drug Substances 0.000 claims abstract description 11
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 claims abstract description 6
- 238000000605 extraction Methods 0.000 claims description 13
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 241000411851 herbal medicine Species 0.000 claims description 10
- 239000000284 extract Substances 0.000 claims description 9
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 claims description 5
- 230000000855 fungicidal effect Effects 0.000 claims description 5
- 239000000417 fungicide Substances 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- 239000000843 powder Substances 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 241000533849 Gleditsia Species 0.000 claims description 3
- 239000009636 Huang Qi Substances 0.000 claims description 3
- 239000003208 petroleum Substances 0.000 claims description 3
- 238000005457 optimization Methods 0.000 claims 2
- 239000006071 cream Substances 0.000 claims 1
- 239000008267 milk Substances 0.000 claims 1
- 210000004080 milk Anatomy 0.000 claims 1
- 235000013336 milk Nutrition 0.000 claims 1
- 239000002994 raw material Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 5
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 abstract description 4
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 abstract description 3
- 230000007797 corrosion Effects 0.000 abstract description 2
- 238000005260 corrosion Methods 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 abstract description 2
- 239000011787 zinc oxide Substances 0.000 abstract description 2
- 210000002683 foot Anatomy 0.000 abstract 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940107666 astragalus root Drugs 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 230000000857 drug effect Effects 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- 230000002421 anti-septic effect Effects 0.000 description 2
- 238000002425 crystallisation Methods 0.000 description 2
- 230000008025 crystallization Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000012467 final product Substances 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 108010084652 homeobox protein PITX1 Proteins 0.000 description 1
- 229910052809 inorganic oxide Inorganic materials 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The novel beriberi and smelly foot treating preparation is compounded with Chinese medicine materials including safflower, angelica, astragalus root, gleditschia horrida, etc. and through solvent extraction to obtain effective matter, and mixing with superfine zinc oxide and titanium oxide as inorganic bactericide. The beriberi and smelly foot treating preparation has fast effect, small dosage, no corrosion, no irritation and no toxic side effect.
Description
It is slow to The present invention be directed to the Chinese medicine compound preparation curative effect, and consumption is big, effective percentage low and the development new formulation.
The present invention adopts extraction process that active ingredient in the Chinese herbal medicine is concentrated extraction, keeps the elite part, so its consumption is few, effective, curative effect is rapid.
The present invention adopts the ultra-fine inorganic oxide, and strong fungicide and Chinese medicine extract cooperate, and can strengthen drug effect greatly, make the product antimicrobial spectrum wider, and curative effect is better.
The object of the invention is specifically clear and definite by following argumentation
The invention provides a kind of preparation with following feature, being about to Chinese herbal medicine pulverizes earlier, cross 40 eye mesh screens, join then in the extraction reactor, add extractant and under 40～80 ℃ of conditions, stir extraction 48 hours, after filtration, with the extract evaporation and concentration, crystallization gets Chinese herbal medicine extract, is basic composition with this extract, add inorganic antiseptic, mix homogeneously is made this agent.Because traditional Chinese medicine preparation working substance content is not concentrated, so consumption is big, drug effect is slow, can not directly add to be sprinkled in the footwear, can only boil the back foot bath for water.And this preparation only needs the about 1～2g of minute quantity to join in the footwear because through purification by liquid extraction, working substance content is high, can cure beriberi, foot odor unconsciously, and directly contacts skin and do not have corrosion, and is non-stimulated, do not cause foot dry and cracked etc.
The present invention has overcome above shortcoming, both kept Chinese herbal medicine Nantural non-toxic, have no side effect, it is few to make it consumption in conjunction with modern science and technology again, drug effect is fast.
The used Chinese medicine of the present invention comprises that Flos Carthami, the Radix Astragali, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Fructus Gleditsia etc. are traditional foot health promotion medications.
The extractant that the present invention uses comprises ether, ethanol, acetone, petroleum ether etc.
The inorganic antiseptic that the present invention uses comprises nano zine oxide, nano-titanium oxide, superfine talcum powder, ultra-fine Maifanitum powder etc.
The technology that the present invention adopts is solvent pressure extraction technology, and wherein pressure is 0.1～1Mpa.
It is ethanol, ether, acetone, petroleum ether that the present invention adopts extractant, wherein is that extractant is best with ethanol, and the extractant consumption is: Chinese herbal medicine powder: extractant 1: 6～10 was the best with 1: 7.5.
The present invention is adjuvant with the inorganic fungicide, comprising nano zine oxide, nano-titanium oxide, superfine talcum powder, ultra-fine Maifanitum powder, wherein is best with the nano zine oxide, and Chinese medicine extract and oxide proportioning were the best with 1: 3 wherein 1: 0.1～5.
The present invention extracted the time at 1～72 hour, was the best with 48 hours wherein.
The used Chinese herbal medicine of the present invention is first pulverizing, pulverizes the order number at 10～80 orders, is the best with 40 orders.
Extraction temperature of the present invention is the best at 10～80 ℃ with 50 ℃.
Gained preparation of the present invention be consumption only 1～2g can in 24 hours, remove foot odor, beriberi.
Gained preparation of the present invention is directly to contact skin, and chafe not is not dry and cracked, no side effects.
Implementation example
Embodiment one
Radix Astragali 30g, Flos Carthami 30g, Radix Angelicae Sinensis 20g, Fructus Gleditsia 20g are pulverized with pulverizer, cross 40 eye mesh screens, add in the extraction reactor, add extractant ethanol 600g, in 0.2Mpa pressure, under 55 ℃ of conditions, extraction 48hr, filter, filtrate when the surface has crystallite to occur, stops evaporation in 78 ℃ of evaporations down, be cooled to 10 ℃ of crystallizations, get Chinese medicine extract 20g.
Get Chinese medicine extract 20g and add nanometer zinc oxide 30g, titanium oxide 20g, Pulvis Talci 50g, mix homogeneously, get final product the about 150g of product.
Embodiment two
In embodiment one, Chinese medicine extract 20g, nano zine oxide 50g, titanium oxide 10g, Pulvis Talci 50g, Maifanitum 10g, vitamin C 10g mixing, get final product the about 150g of product.
Claims (6)
1. the present invention skims the cream off milk through extraction process for being raw material with the Chinese herbal medicine, adds inorganic fungicide again and a kind of preparation method of removing foot odor, beriberi preparation of making.Its feature comprises the Chinese herbal medicine compositing formula, extraction process, pressure, temperature, Chinese herbal medicine and inorganic fungicide proportioning etc.
2. the present invention such as right 1 require preparation method, extraction process optimization, formula and prescription optimization etc.
3. the present invention requires the Chinese herbal medicine composition to comprise Flos Carthami, the Radix Astragali, Radix Angelicae Sinensis, Radix Sophorae Flavescentis, Fructus Gleditsia etc.
4. inorganic fungicide of the present invention comprises nano zine oxide, nano-titanium oxide, superfine talcum powder, ultra-fine Maifanitum powder.
5. the present invention such as right 1,2 require preparation method, and requiring extractant is that ethanol, ether, petroleum ether, acetone, extracting pressure are 0.1～1Mpa, and extraction temperature is 10～80 ℃.
6. the present invention such as right 1 requirement, Chinese medicine extract and oxide proportioning 1: 01～10.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021254230A CN1473577A (en) | 2002-08-07 | 2002-08-07 | Process for preparing special preparation for curing beriberi and smelly foot |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA021254230A CN1473577A (en) | 2002-08-07 | 2002-08-07 | Process for preparing special preparation for curing beriberi and smelly foot |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1473577A true CN1473577A (en) | 2004-02-11 |
Family
ID=34142886
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA021254230A Pending CN1473577A (en) | 2002-08-07 | 2002-08-07 | Process for preparing special preparation for curing beriberi and smelly foot |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1473577A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297250C (en) * | 2005-03-18 | 2007-01-31 | 张宗田 | Medicinal powder for eliminating human body off odour |
| CN105287311A (en) * | 2015-12-01 | 2016-02-03 | 广州丹奇日用化工厂有限公司 | Traditional Chinese medicine composition for foot care |
| CN109395049A (en) * | 2018-12-29 | 2019-03-01 | 陈欣欣 | A kind of probiotics berberi powder and preparation method thereof |
| CN109529086A (en) * | 2018-12-12 | 2019-03-29 | 吴世魁 | A kind of multifunctional nano deodorizing sterilizing anionic additive and preparation method thereof |
-
2002
- 2002-08-07 CN CNA021254230A patent/CN1473577A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1297250C (en) * | 2005-03-18 | 2007-01-31 | 张宗田 | Medicinal powder for eliminating human body off odour |
| CN105287311A (en) * | 2015-12-01 | 2016-02-03 | 广州丹奇日用化工厂有限公司 | Traditional Chinese medicine composition for foot care |
| CN109529086A (en) * | 2018-12-12 | 2019-03-29 | 吴世魁 | A kind of multifunctional nano deodorizing sterilizing anionic additive and preparation method thereof |
| CN109395049A (en) * | 2018-12-29 | 2019-03-01 | 陈欣欣 | A kind of probiotics berberi powder and preparation method thereof |
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