CN117860619A - A skin caring composition containing wild soybean oil - Google Patents
A skin caring composition containing wild soybean oil Download PDFInfo
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- CN117860619A CN117860619A CN202310160252.XA CN202310160252A CN117860619A CN 117860619 A CN117860619 A CN 117860619A CN 202310160252 A CN202310160252 A CN 202310160252A CN 117860619 A CN117860619 A CN 117860619A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
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- A61P17/00—Drugs for dermatological disorders
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The invention relates to a medical skin care product composition, in particular to a skin care composition containing wild soybean oil, which comprises the following raw materials: wild soybean (GLYCINE SOJA) oil, detergent, tocopheryl acetate and laureth-4; wherein the cleaning agent is mixture of laureth sulfate MIPA salt, laureth-4 and propylene glycol. The invention takes the wild soybean oil as the main material and takes the raw materials such as tocopheryl acetate, the cleaning agent and the like as the auxiliary materials, can reduce the irritation caused by the surfactant, and simultaneously, the grease with high addition amount can give the skin sufficient moistening degree, so that the skin can be cleaned, dirt and dust can be removed, the reduced surface lipid film on the skin can be supplemented, the increased percutaneous moisture loss is normalized, and the loss of natural moisturizing factors in the bathing process is reduced, thereby regenerating the barrier function of the skin.
Description
Technical Field
The invention relates to a medical skin care product composition, in particular to a skin care composition containing wild soybean oil.
Background
Dermatitis eczema is one of the most common diseases of dermatology, has high incidence rate, and the impaired skin barrier function is a key factor of the incidence of the skin, so that the transepidermal water loss is increased, the water content of the horny layer is reduced, the capability of resisting external sensitization substances is reduced, the skin is repeatedly dry, scale and chapped, the itching is obvious, and part of patients feel anxiety, dysphoria and restlessness for a long time, and the life is seriously influenced. The glucocorticoid treatment can effectively relieve symptoms and control illness state, but is easy to recur, and the skin barrier damage can be aggravated after long-term use. Repair of skin barrier function is extremely important and necessary in the treatment of dermatitis eczema.
It was found through research that excessive cleaning is one of factors causing eczema. Improper bathing increases the external adverse irritation to the skin, exacerbating skin barrier dysfunction. Proper bathing is important in improving atopic dermatitis. Reasonable cleansing is a key point to protect sebum, reduce the incidence of atopic dermatitis. Improper bathing can increase the external undesirable irritation to the skin, exacerbating skin barrier dysfunction. By studying the role of excessive cleansing in the development of eczema, it was found that frequent and prolonged hot water bathing, excessive use of alkalinity, chemicals and little use of emollients are important risk factors leading to disruption of the stratum corneum barrier.
The existing bath cream product contains various chemical finished products, so that the bath cream product is easy to excessively use, the skin can be dried, itched and uncomfortable after bath, the effect is poor after use for part of people, and even a series of skin problems are caused.
Disclosure of Invention
The invention aims to provide a skin-moisturizing and repairing composition containing wild soybean oil, which takes the wild soybean oil as a main material and is supplemented with raw materials such as tocopheryl acetate, a cleaning agent and the like, so that the irritation caused by a surfactant can be reduced, and meanwhile, grease with high addition amount can give the skin sufficient moisturizing degree, so that the skin can be cleaned, dirt and dust of the skin can be removed, and the loss of moisture of the skin in the cleaning process can be reduced.
In order to achieve the above purpose, the invention adopts the following technical scheme
A skin care composition containing wild soybean oil component comprises the following raw materials: wild soybean (Glycine SOJA) oil, cleaning agent, tocopheryl acetate and laureth-4, wherein the cleaning agent is mixture of laureth sulfate MIPA salt, laureth-4 and propylene glycol;
the skin care composition containing the wild soybean oil component is applied to a composition for treating atopic dermatitis, seborrheic dermatitis, photosensitive dermatitis and eczema or applied to bath cleaning cosmetics as a raw material.
Preferably, the skin care composition containing the wild soybean oil component comprises the following raw materials in percentage by weight:
64.0 to 84.9 percent of wild soybean oil,
10.0 to 20.0 percent of cleaning agent,
0.1 to 1.0 percent of tocopheryl acetate,
5.0 to 15.0 percent of laureth.
Preferably, the skin care composition containing the wild soybean oil component comprises the following raw materials in percentage by weight:
84.4 percent of wild soybean oil,
10.0 percent of cleaning agent,
0.2 percent of tocopheryl acetate,
laureth-4.4%.
Preferably, the skin care composition containing the wild soybean oil component comprises the following raw materials in percentage by weight:
77.495 percent of wild soybean oil,
14.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
Preferably, the skin care composition containing the wild soybean oil component comprises the following raw materials in percentage by weight:
69.495 percent of wild soybean oil,
20.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
Preferably, the cleaning agent comprises the following components in parts by weight (3-6): (2-5): 2, laureth sulfate MIPA salt, laureth-4 and propylene glycol.
A method for preparing a skin care composition containing wild soybean oil component comprises the following steps:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
Preferably, in S1, the main pot is added, then the stirring and heating are carried out, the rotating speed of the stirrer is 25r/min, and the temperature is heated to 75 ℃.
Preferably, in S1, during stirring, the rotation speed of the stirrer is increased by 5r/min, and then reduced by 5r/min until 25r/min after 40 r/min.
Preferably, in S1, the step heating is performed by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is performed by adopting a mode of heat preservation for 2min at every temperature of 10 ℃.
The invention has the beneficial effects that:
1. the invention takes the wild soybean oil as the main material and takes the raw materials such as the tocopheryl acetate, the cleaning agent and the like as the auxiliary materials, so that the irritation caused by the surfactant can be reduced, and meanwhile, the grease with high addition amount can give the skin sufficient moistening degree, so that the skin can be cleaned, dirt and dust of the skin can be removed, and the loss of skin moisture in the bathing process can be reduced. It also supplements the reduced surface lipid membrane on the skin, normalizes increased transdermal water loss, and reduces the loss of natural moisturizing factors during bathing, thereby regenerating the skin's barrier function.
2. The formula of the invention adopts vegetable oil: the soybean oil is used as a basic formula matrix, so that the irritation brought by cleaning is reduced, the surface lipid film of the skin is supplemented, the skin is mild in effect, the skin is moistened and cleaned by being matched with a cleaning agent and a surfactant, the humectant has the antioxidant effect, the oxidation of the skin lipid protective layer is delayed, and the sebum protective layer of a human body is effectively enhanced. The cleaning agent and the surfactant with the optimal proportion are selected, so that the cleaning performance of the skin is ensured, and the damage to the skin caused by excessive cleaning is avoided; in addition, VE oil is added, so that the oxidation resistance of bath oil is improved, the stability of the bath oil is ensured, and meanwhile, the lipid which is lost by skin is supplemented.
Description of the embodiments
The following description of the embodiments of the present invention will be made clearly and completely, and it is apparent that the described embodiments are only some embodiments of the present invention, but not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
84.4 percent of wild soybean oil,
10.0 percent of cleaning agent,
0.2 percent of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 1, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
74.495 percent of wild soybean oil,
10.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 2, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
77.495 percent of wild soybean oil,
14.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 3, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
69.495 percent of wild soybean oil,
20.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 4, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
78.6 percent of wild soybean oil,
12.0 percent of cleaning agent,
tocopheryl acetate 1.0%,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 5, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
78.495 percent of wild soybean oil,
13.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 6, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Examples
A skin care composition containing wild soybean oil comprises the following raw materials in percentage by weight:
76.1 percent of wild soybean oil,
15.0 percent of cleaning agent,
0.5 percent of tocopheryl acetate,
laureth-4.4%.
A method of preparing a skin care composition comprising a wild soybean oil component as described in example 7, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean (Glycine SOJA) oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, heating to 70-80 ℃ at the rotating speed of 20-40r/min, continuously stirring until the mixture is completely and uniformly dissolved and reaches a homogeneous state, and cooling to room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
In S1, adding the main pot, stirring and heating, wherein the rotating speed of a stirrer is 25r/min, and heating to 75 ℃; in the stirring process, the rotating speed of the stirrer is regulated up at a speed of 5r/min, and is regulated down at a speed of 5r/min until the rotating speed reaches 40r/min, until the rotating speed reaches 25r/min; the step heating is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃, and the step cooling is carried out by adopting a mode of heat preservation for 2min at every temperature of 10 ℃ when the temperature is reduced.
Test example 1
The raw materials of the skin-caring cosmetic containing the wild soybean oil component prepared in examples 1 to 7 were tested for the presence or absence of off-flavor, shelf life, bacteria detection, heavy metal detection and toxicity detection, and the results were as follows.
List one
According to analysis of test results, the raw materials of the skin-moistening and repairing cosmetics containing the wild soybean oil component, which are prepared by the invention, accord with the national cosmetic sanitation standard.
Test example two
The raw materials of the skin-care cosmetics containing the wild soybean oil component prepared in examples 1 to 7 were tested for heat stability, light stability, anti-corrosion challenge test, soothing effect and cleansing effect, and the results were as follows.
Watch II
From the analysis of test results, it is found that the raw material of the skin-moisturizing and repairing cosmetic containing the wild soybean oil component prepared by the invention has both the cleansing effect and the soothing effect, and the skin which is excessively clean is repaired, wherein the best effect is obtained in example 3.
Wherein, the wild soybean oil is oil extracted from soybean, and the wild soybean oil contains 7-10% of palmitic acid, 2-5% of stearic acid, 1-3% of arachidic acid, 22-30% of oleic acid, 50-60% of linoleic acid and 5-9% of linoleic acid. The fatty acid composition of wild soybean oil is good, and it contains rich linoleic acid, vitamin E, vitamin D and rich lecithin. The human body digestion and absorption rate of the soybean oil is up to 98%. It has effects of moistening skin, removing fat, nourishing liver, resisting aging, and caring skin, and can be used for improving amnesia, insomnia, senilism, xerosis cutis, and pachylosis. Contains abundant nutrients such as isoflavone, fatty acid, vitamins, etc., and can help strengthen skin barrier, tighten loose skin, and improve skin elasticity around pores. The wild soybean oil contains abundant amino acids, so that the wild soybean oil can nourish skin, relieve dryness and roughness of skin, and enable the skin to be durable, smooth and tender and soft to touch. The linoleic acid can effectively prevent the synthesis of melanin in skin cells, has good whitening effect, and can effectively improve skin aging. The isoflavone in the wild soybean oil is a chemical component with a structure similar to that of estrogen, is a plant estrogen with estrogenic activity, can delay female cell aging, ensures that skin keeps elastic, and is a natural raw material for maintaining beauty and keeping young. The plant estrogen also has effect of relieving climacteric syndrome. Bath oil prepared from cosmetic materials containing high proportion of wild soybean oil as main body has been shown in studies to have antipruritic effect in 2-3 times per week, and helps break the cycle of malignant pruritus-scratching, thereby preventing deterioration, secondary infection and potential sleep deficiency. The bath oil product containing soybean oil can relieve itching and improve skin dryness, has good tolerance to bath oil for children, can reduce use of steroid and other medicines, and greatly saves cost for patients.
Tocopherol is an important antioxidant, and the aim of inhibiting the oxidation of grease is achieved mainly by removing unsaturated lipid free radicals in the grease. In addition, due to the degree of methylation of different tocopherols, the antioxidant activity of different tocopherols is also different. The tocopheryl acetate is used as a tocopheryl ester derivative, on one hand, the tocopheryl acetate is used as a humectant to be added into a skin care composition, so that the skin moisturizing effect is better, and on the other hand, the tocopheryl acetate is used as an antioxidant, so that the oxidation reaction in the grease storage process can be effectively prevented, the oxidation of the grease is delayed, and the good stability of the product period is ensured. The tocopherol ester derivatives have wide application in the cosmetic industry due to the improvement of surface activity. The oleate, palmitate, carboxylate, myristate and linolenate of tocopherol can be used as moisturizing components to make skin moisturized, so as to attain the goal of preventing skin aging. The tocopheryl linoleate is a tocopheryl derivative for deeply moistening skin cells, can help to reduce wrinkles and prevent free radicals from damaging the skin cells, is mainly used for preparing high-grade cosmetics, and has the effects of moisturizing skin and hair, resisting aging and the like. At the same time, tocopheryl esters are also highly active antioxidants, antiallergic and anti-inflammatory agents and anti-uv agents. Such as tocopherol sorbate, isostearate, ferulate, acetate, etc., has effects of absorbing ultraviolet rays and protecting skin.
Dermatitis and eczema are common diseases and frequently-occurring diseases of dermatology, mainly comprise atopic dermatitis, seborrheic dermatitis, photosensitive dermatitis, hormone-dependent dermatitis and eczema, are external application indications of glucocorticoid, and can control symptoms after being used for (1-2) weeks; however, if the glucocorticoid is used for a long time or abused, adverse reactions such as skin atrophy and thinning, hair enlargement, telangiectasia, pigment abnormality, hormone dependence and rebound, aggravation of acne, folliculitis induction and the like can occur. The medical skin care product is applied to dermatitis eczema, can restore skin barrier, effectively relieve symptoms, properly shorten the treatment course of hormone use, avoid hormone side effects, prevent recurrence and the like, and is a good choice for dermatitis eczema patients. Has wide application in clinical and daily treatment processes.
Medical skin care products (Dermocosmetic) are not strictly defined in China, are called "efficacy cosmetics" or "Cosmeceuticals" in foreign countries, are third products which are among cosmetics and medicines and are essentially cosmetics instead of medicines, are often used as auxiliary treatment means for skin diseases due to the safety, efficacy, clinical and experimental verification and the like [2], play an important role in scientific management of various skin diseases, and can effectively improve photoaging, dryness and inflammatory skin diseases such as atopic dermatitis, seborrheic dermatitis, photosensitive dermatitis, hormone-dependent dermatitis, eczema and the like through combined drug treatment. In addition, the skin care product can be used for auxiliary treatment of hyperhidrosis, bromhidrosis, alopecia, poliosis, etc. The active ingredients contained in the medical skin care product are natural plants, minerals, chinese herbal medicine extracts and the like, so that the medical skin care product has high safety, no toxic or side effect, can eliminate the use concern of consumers, can meet the requirements of consumers on skin body building while treating skin diseases, and has wide efficacy.
The test example of the invention is that according to 2007 cosmetic health Specification and 2015 cosmetic safety Specification as reference standards, the detection method refers to GB/T13531.1-2008, the anti-corrosion challenge test refers to a single anti-corrosion challenge test method recommended by PCPC (American personal care product Association, commonly referred to as CTFA) for 28 days, and the relieving effect and the cleaning effect are tested by adopting the test method in 2015 edition of cosmetic safety Specification and the seventh chapter human body safety test method.
In the description of the present specification, the descriptions of the terms "one embodiment," "example," "specific example," and the like, mean that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the present invention. In this specification, schematic representations of the above terms do not necessarily refer to the same embodiments or examples. Furthermore, the particular features, structures, materials, or characteristics described may be combined in any suitable manner in any one or more embodiments or examples.
Finally, it should be noted that the above-disclosed preferred embodiments of the invention are merely intended to help illustrate the invention. The preferred embodiments are not exhaustive or to limit the invention to the precise form disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best understand and utilize the invention. The invention is limited only by the claims and the full scope and equivalents thereof.
Claims (10)
1. A skin care composition comprising a wild soybean oil component, characterized by: the material consists of the following raw materials: the cleaning agent comprises wild soybean oil, a cleaning agent, tocopheryl acetate and laureth-4, wherein the cleaning agent is a mixture of laureth sulfate MIPA salt, laureth-4 and propylene glycol;
the skin care composition containing the wild soybean oil component is applied to a composition for treating atopic dermatitis, seborrheic dermatitis, photosensitive dermatitis and eczema or applied to bath cleaning cosmetics as a raw material.
2. The skin care composition containing wild soybean oil component as claimed in claim 1, wherein the composition comprises the following raw materials in percentage by weight:
64.0 to 84.9 percent of wild soybean oil,
10.0 to 20.0 percent of cleaning agent,
0.1 to 1.0 percent of tocopheryl acetate,
5.0 to 15.0 percent of laureth.
3. The skin care composition containing wild soybean oil component according to claim 2, which is characterized by comprising the following raw materials in percentage by weight:
84.4 percent of wild soybean oil,
10.0 percent of cleaning agent,
0.2 percent of tocopheryl acetate,
laureth-4.4%.
4. The skin care composition containing wild soybean oil component according to claim 2, which is characterized by comprising the following raw materials in percentage by weight:
77.495 percent of wild soybean oil,
14.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
5. The skin care composition containing wild soybean oil component according to claim 2, which is characterized by comprising the following raw materials in percentage by weight:
69.495 percent of wild soybean oil,
20.0 percent of cleaning agent,
0.105% of tocopheryl acetate,
laureth-4.4%.
6. The skin care composition containing a wild soybean oil component according to claim 1, wherein the cleansing agent is (3-6) by weight: (2-5): 2, laureth sulfate MIPA salt, laureth-4 and propylene glycol.
7. A method of preparing a skin care composition comprising a wild soybean oil component according to any one of claims 1 to 5, comprising the steps of:
s1, in a sterile environment and at room temperature, sequentially adding wild soybean oil, a cleaning agent, tocopheryl acetate and laureth-4 into a main pot, stirring and heating, wherein the rotating speed of a stirrer is 20-40r/min, heating to 70-80 ℃, continuing stirring until the materials are completely and uniformly dissolved and reach a homogeneous state, and cooling to the room temperature;
s2, checking, and filtering and discharging after the checking is qualified;
s3, checking and filling semi-finished products;
s4, packaging, checking and warehousing.
8. The method for preparing a skin care composition containing a wild soybean oil ingredient as claimed in claim 7, wherein in S1, after adding into the main pot, stirring and heating, the rotation speed of the stirrer is 25r/min, and heating to 75 ℃.
9. The method for preparing a skin care composition containing a wild soybean oil component according to claim 8, wherein in S1, the rotation speed of the stirrer is adjusted to be higher by 5r/min, and is adjusted to be lower by 5r/min until 25r/min after reaching 40r/min during stirring.
10. The method for preparing a skin care composition containing a wild soybean oil component according to claim 8, wherein in S1, step heating is performed by heating at 10 ℃ for 2 min.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108420774A (en) * | 2018-05-29 | 2018-08-21 | 北京明弘科贸有限责任公司 | A kind of moist shower cream and preparation method thereof |
| CN111067820A (en) * | 2018-10-19 | 2020-04-28 | 酷美生物科技（上海）有限公司 | Plant repair essence milk and preparation method thereof |
| WO2022252761A1 (en) * | 2021-05-31 | 2022-12-08 | 植然天成(北京)生物科技有限公司 | Soothing repair cream and preparation method therefor |
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| CN108420774A (en) * | 2018-05-29 | 2018-08-21 | 北京明弘科贸有限责任公司 | A kind of moist shower cream and preparation method thereof |
| CN111067820A (en) * | 2018-10-19 | 2020-04-28 | 酷美生物科技（上海）有限公司 | Plant repair essence milk and preparation method thereof |
| WO2022252761A1 (en) * | 2021-05-31 | 2022-12-08 | 植然天成(北京)生物科技有限公司 | Soothing repair cream and preparation method therefor |
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