CN117482011B

CN117482011B - Anti-allergy and soothing plant composition and application thereof

Info

Publication number: CN117482011B
Application number: CN202311578724.XA
Authority: CN
Inventors: 洪奇; 徐鑫; 朱羿玮
Original assignee: Meishang Guangzhou Cosmetics Co ltd
Current assignee: Meishang Guangzhou Cosmetics Co ltd
Priority date: 2023-11-24
Filing date: 2023-11-24
Publication date: 2024-06-28
Anticipated expiration: 2043-11-24
Also published as: CN117482011A

Abstract

The invention relates to the technical field of cosmetics, in particular to an antiallergic and soothing plant composition and application thereof, and the technical scheme is characterized by comprising the following raw materials in parts by weight: 0.1-10 parts of inonotus obliquus mixture and 0.1-10 parts of guaiacum mixture; wherein the inonotus obliquus mixture comprises inonotus extract, lactobacillus fermentation lysate, first polyol and preservative, and the guaiacum mixture comprises water, guaiacum extract, second polyol and antioxidant. The invention is safe and mild, can promote and maintain the moisture content of the skin, enables the skin to recover to a healthy state, and has excellent anti-allergy, relieving and repairing effects.

Description

Anti-allergy and soothing plant composition and application thereof

Technical Field

The invention relates to the technical field of cosmetics, in particular to an antiallergic and soothing plant composition and application thereof.

Background

The skin is directly contacted with the external environment, and has the functions of protecting, excreting, regulating body temperature, sensing external stimulus and the like, and is the largest organ in human body organs. However, when the environment changes, air pollution, ultraviolet radiation, irregular life and work, working and living pressure, excessive use of cosmetics and the like, skin receives more and more stimulation, various skin problems (water loss, damaged sebum membrane balance, damaged barrier, redness, itching and the like) are generated in the process of stress, and the skin becomes fragile and sensitive.

The cosmetics with skin soothing effect on the market are various, and chemical medicines are used in a large amount because of quick effect, but side effects are increasingly developed, and skin barriers can be damaged by serious side effects, so that irreversible damage is formed to skin.

In addition, another type of cosmetics is popular by seeking active ingredients from plants or medicinal materials that antagonize the irritation source of the cosmetics, because of their mild effects and low side effects. However, the development types of plant cosmetics related to anti-allergy and soothing are few, the cosmetics are not easy to be absorbed by skin, and the efficacy is relatively slow and single.

Disclosure of Invention

Aiming at the defects existing in the prior art, the invention aims to provide an antiallergic and soothing plant composition and application thereof, and the plant composition has the advantages of safe and mild action, quick response and excellent antiallergic and soothing effects.

The technical aim of the invention is realized by the following technical scheme, and the antiallergic and soothing plant composition comprises the following raw materials in parts by weight: 0.1-10 parts of inonotus obliquus mixture and 0.1-10 parts of guaiacum mixture;

Wherein the inonotus obliquus mixture comprises inonotus extract, lactobacillus fermentation lysate, first polyol and preservative, and the guaiacum mixture comprises water, guaiacum extract, second polyol and antioxidant.

In one embodiment, the mass ratio of the inonotus obliquus mixture to the guaiac mixture is 1:1.

In one embodiment, the inonotus obliquus mixture comprises the following components in percentage by mass: 60-70% of inonotus obliquus extract, 25-31% of lactobacillus fermentation lysate, 4.1-8.5% of first polyol and 0.2-1.2% of preservative.

In one embodiment, the first polyol comprises at least one of glycerol and 1, 3-propanediol and the preservative comprises at least one of octanoyl hydroxamic acid and 1, 2-hexanediol.

In one embodiment, the inonotus obliquus extract and the lactobacillus fermentation lysate are prepared by the steps of: pulverizing Inonotus obliquus raw materials, adding lactobacillus for fermentation to obtain fermentation liquor, and vacuum concentrating the fermentation liquor to obtain the target product.

In one embodiment, the guaiac mixture comprises the following components in percentage by mass: 3-4% of guaiacum extract, 1-10% of second polyol, 0.2-0.8% of antioxidant and the balance of water.

In one embodiment, the second polyol comprises one or more of propylene glycol, glycerin, and butylene glycol, and the antioxidant comprises one or more of p-hydroxyacetophenone, ascorbic acid, an ascorbic acid derivative, tocopherol, and tocopheryl acetate.

In one embodiment, the guaiacum extract is prepared by the steps of: and sequentially carrying out crushing, alcohol extraction, vacuum concentration and sterilization treatment on the guaiacum raw material to obtain the guaiacum extract.

A cosmetic comprises a base material and functional components, wherein the functional components are the antiallergic and soothing plant composition.

In one embodiment, the plant composition is 0.2-20% by mass of the cosmetic.

The plant composition for resisting allergy and relieving as well as the preparation method and the application thereof have the following beneficial effects:

Firstly, the inonotus obliquus and guaiacum are compounded, the raw materials are safe and mild, the inonotus obliquus and guaiacum complement each other, the synergistic effect is achieved, the onset time is quick, various symptoms such as burning stinging, tightening and drying, skin reddening, skin itching and dry itching are improved, and the inonotus obliquus and guaiacum compound extract has excellent anti-allergic, soothing, anti-inflammatory and repairing effects;

Secondly, the inonotus obliquus and guaiacum can be matched to effectively maintain and improve the moisture content of the skin, further relieve the skin, repair the skin barrier and enable the skin to be restored to a healthy state;

thirdly, the inonotus obliquus extract is prepared by a lactobacillus fermentation method, and a byproduct lactobacillus fermentation lysate has good anti-inflammatory and skin conditioning effects;

Fourth, the prepared plant composition can be directly added into cosmetic base materials, such as face cream, skin care water, essence, facial mask, shampoo, bath lotion and the like, has wide application direction, and enables the obtained cosmetics to have anti-inflammatory and soothing effects.

Detailed Description

The present invention will be described in further detail with reference to the following examples, which are intended to facilitate the understanding of the present invention without any limitation thereto. Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. In case of conflict, the present specification, definitions, will control.

The term "prepared from …" as used herein is synonymous with "comprising". The terms "comprising," "including," "having," "containing," or any other variation thereof, as used herein, are intended to cover a non-exclusive inclusion. For example, a composition, step, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but may include other elements not expressly listed or inherent to such composition, step, method, article, or apparatus.

The conjunction "consisting of …" excludes any unspecified element, step or component. If used in a claim, such phrase will cause the claim to be closed, such that it does not include materials other than those described, except for conventional impurities associated therewith. When the phrase "consisting of …" appears in a clause of the claim body, rather than immediately following the subject, it is limited to only the elements described in that clause; other elements are not excluded from the stated claims as a whole.

When an equivalent, concentration, or other value or parameter is expressed as a range, preferred range, or a range bounded by a list of upper preferable values and lower preferable values, this is to be understood as specifically disclosing all ranges formed from any pair of any upper range limit or preferred value and any lower range limit or preferred value, regardless of whether ranges are separately disclosed. For example, when ranges of "1 to 5" are disclosed, the described ranges should be construed to include ranges of "1 to 4", "1 to 3", "1 to 2 and 4 to 5", "1 to 3 and 5", and the like. When a numerical range is described herein, unless otherwise indicated, the range is intended to include its endpoints and all integers and fractions within the range.

The present invention will be described in detail with reference to examples.

An antiallergic and soothing plant composition comprises the following raw materials in parts by weight: 0.1-10 parts of inonotus obliquus mixture and 0.1-10 parts of guaiacum mixture;

Wherein the inonotus obliquus mixture comprises inonotus extract, lactobacillus fermentation lysate, first polyalcohol and antiseptic, and the guaiacum mixture comprises water, guaiacum extract, second polyalcohol and antioxidant.

According to the invention, through the compounding of two plant extract components of inonotus obliquus and guaiacum, the raw materials are safe and mild, the two are mutually complemented, the synergistic effect is achieved, the onset time is quick, various symptoms such as burning stinging, tightening and drying, skin reddening, skin itching and dry itching are improved, and the inonotus obliquus and guaiac compound extract has excellent anti-allergic, soothing, anti-inflammatory and repairing effects; and the inonotus obliquus and guaiacum can be matched to effectively maintain and improve the moisture content of skin, further relieve the skin, repair the skin barrier and restore the skin to a healthy state.

Specifically, the mass ratio of the inonotus obliquus mixture to the guaiac mixture is 1:1.

Specifically, the inonotus obliquus mixture comprises the following components in percentage by mass: 60-70% of inonotus obliquus extract, 25-31% of lactobacillus fermentation lysate, 4.1-8.5% of first polyol and 0.2-1.2% of preservative. The inonotus obliquus mixture is obtained by weighing and uniformly mixing the components according to the proportion.

Further, the first polyol includes at least one of glycerin and 1, 3-propanediol, and the preservative includes at least one of octanoyl hydroxamic acid and 1, 2-hexanediol.

Further, the inonotus obliquus extract and the lactobacillus fermentation lysate are prepared by the following steps: pulverizing Inonotus obliquus raw material, adding lactobacillus for fermentation to obtain fermentation liquor, and vacuum concentrating the fermentation liquor to obtain target product.

In the invention, the inonotus obliquus extract is prepared by adopting a lactobacillus fermentation method, and a byproduct lactobacillus fermentation lysate has good anti-inflammatory and skin conditioning effects;

specifically, the guaiac mixture comprises the following components in percentage by mass: 3-4% of guaiacum extract, 1-10% of second polyol, 0.2-0.8% of antioxidant and the balance of water. The guaiac mixture is obtained by weighing and uniformly mixing the above components in proportion.

Further, the second polyol comprises one or more of propylene glycol, glycerin, and butylene glycol, and the antioxidant comprises one or more of p-hydroxyacetophenone, ascorbic acid, an ascorbic acid derivative, tocopherol, and tocopheryl acetate.

Further, the guaiacum extract is prepared by the steps of: the guaiacum raw material is orderly crushed, extracted by alcohol, concentrated in vacuum and sterilized to obtain guaiacum extract.

A cosmetic comprises base material and effective components, wherein the effective components are the plant composition with antiallergic and soothing effects.

The prepared plant composition can be directly added into cosmetic base materials such as face cream, skin care water, essence, facial mask, shampoo, bath lotion and the like as effective components, has wide application direction, and ensures that the obtained cosmetics have the effects of resisting inflammation and relieving.

Specifically, the mass percentage of the plant composition in the cosmetics is 0.2-20%; further, the plant composition accounts for 0.3-12% of the total mass of the cosmetic.

Example 1

The embodiment provides an antiallergic and soothing plant composition, which comprises the following raw materials in parts by weight: 6g of inonotus obliquus mixture and 10g of guaiac mixture;

the inonotus obliquus mixture comprises the following components in percentage by mass: 65% Inonotus obliquus extract, 28% lactobacillus fermentation lysate, 6.2% glycerol and 0.8% octanoyl hydroxamic acid;

The guaiac mixture comprises the following components in percentage by mass: 3.5% guaiacum extract, 3% butanediol, 0.5% p-hydroxyacetophenone and 93% water.

Wherein, the preparation method of the inonotus obliquus extract and lactobacillus fermentation lysate is as follows: crushing inonotus obliquus raw materials, adding lactobacillus for fermentation to obtain fermentation liquor, and carrying out vacuum concentration on the fermentation liquor to obtain a target product;

the preparation method of the guaiacum extract comprises the following steps: the guaiacum raw material is orderly crushed, extracted by alcohol, concentrated in vacuum and sterilized to obtain guaiacum extract.

Example 2

The present example provides an antiallergic soothing plant composition which differs from example 1 only in that it comprises the following raw materials in parts by weight: 6g of inonotus obliquus mixture and 30g of guaiac mixture.

Example 3

The present example provides an antiallergic soothing plant composition which differs from example 1 only in that it comprises the following raw materials in parts by weight: inonotus obliquus mixture 30g, guaiac mixture 30g.

Example 4

The present example provides an antiallergic soothing plant composition which differs from example 1 only in that it comprises the following raw materials in parts by weight: inonotus obliquus mixture 30g, guaiac mixture 10g.

Example 5

The present example provides an antiallergic soothing plant composition which differs from example 1 only in that it comprises the following raw materials in parts by weight: inonotus obliquus mixture 2g, guaiac mixture 1g.

Table 1 shows the cosmetics containing the plant composition provided by the invention and experimental data of comparison test thereof, and the cosmetics are particularly essence. In this test, the plant compositions used in application examples 1 to 5 were examples 1 to 5, respectively, the inonotus obliquus mixture used in comparative example 1 was identical in specific components and mass% to the inonotus obliquus mixture in example 1, and the guaiacum mixture used in comparative example 2 was identical in specific components and mass% to the guaiacum mixture in example 1.

TABLE 1

Application examples 1-5, comparative examples 1-2 and the control group were prepared as follows:

S1, placing the basic raw materials (sequence numbers 1-6) into a beaker, heating to 80 ℃ while stirring, stirring until the materials are clear and transparent, and cooling to 30 ℃ for standby;

S2, adding the functional components into the mixture obtained in the step S1 according to a proportion, and uniformly mixing.

Test 1: and testing the using effect of the human body.

Test population: 72 volunteers, each of which had different degrees of redness and sensitive discomfort on the face and body parts, were randomly divided into 12 groups, and the products of application examples 1-5, comparative examples 1-2 and control groups were used in units of groups, respectively.

The testing method comprises the following steps: all volunteers spread the product on the whole face and part of the body (arms, back of hand, neck) in an amount of 2g each time, once a day in the morning and evening, for 7 consecutive days without other skin care products or products of similar efficacy; after the use, the product is evaluated by adopting a scoring system, the improvement condition (burning and stinging, tightening and drying, skin reddening and skin itching and dry itching) of various symptoms is scored, the score is divided into 5 scores, and the higher the score is, the better the relieving effect is. The four improved scores are then summed and averaged to obtain the overall relief improvement score.

The test results are shown in table 2:

TABLE 2

Looking at the overall relief results, application examples 1-5 all performed better than the control. The essence added with the inonotus obliquus and the guaiac has better soothing effect on the skin. The application example 3 and the comparison examples 1 and 2 are added with 6% of the effective components, and the improvement effect of the application example 3 is more excellent, and the inonotus obliquus mixture and the guaiac mixture have a synergistic effect.

Test 2: and (5) testing the moisturizing efficacy.

The testing method comprises the following steps: the multifunctional skin tester with Real Bubee intelligent digital display is used on the inner side of the forearm of the arm to test the skin moisture values before and after using the product (15 minutes), 3 groups of people are tested together, and the average value is obtained.

Test sample: application example 3, comparative example 1, comparative example 2 and control group.

The test results are shown in table 3:

	Basic value	After 15 minutes	Difference (moisture added value)
				Application example 3	25％	46％	21％
Comparative example 2	25％	37％	12％
				Comparative example 1	25％	41％	16％
Control group	25％	30％	5％

TABLE 3 Table 3

Application example 3 and comparative examples 1 and 2 each had 6% of the functional ingredient added thereto, and application example 3 had a more excellent moisture increasing (moisturizing) effect than comparative examples 1, 2 and control groups.

Test 3: the tape tearing test on the inner side of the arm (immediate redness improvement due to barrier damage).

The testing method comprises the following steps: on the inner side of the forearm of the left arm, 4 areas with the size of 1.5cm x2cm are drawn, the 3M adhesive tape is used for tearing for about 10 times on average, obvious reddening appears at the tearing position, after the reddening of the 4 areas with the size is consistent, the sample is smeared on each area, and the time is calculated. This test n=1.

When the time is 60 minutes, the redness of the application example 3 completely disappears, while the comparative examples 1 and 2 still have light red marks, the redness of the control group is clearly visible, and the application example 3 can better eliminate the redness caused by the damage of the barrier.

Test 4: histamine sensitization test.

The testing method comprises the following steps: firstly, preparing a 5% aqueous solution of histamine diphosphate monohydrate (HISTAMINE BISPHOSPHATE MONOHYDRATE) for later use; on the inside of the left arm, 4 1.5cm x 2cm size areas were drawn, the skin began to feel itchy and tingling after 30 minutes of wet application of the aqueous histamine solution, and then comparative example 2, comparative example 1, application example 3 and control group were applied in this order from the upper arm to the lower arm, and the time was calculated. This test n=1.

After 30 minutes, the control had a significantly small rash and had a feeling of itching all the time, and the control 1 and control 2 had a slightly small rash around them but no feeling of itching, and application 3, which was the best, had no redness and rash, and no feeling of itching. Application example 3 can suppress the appearance of sensitive symptoms better.

The foregoing examples illustrate only a few embodiments of the invention and are described in detail herein without thereby limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims

1. An antiallergic and soothing plant composition is characterized by comprising the following raw materials in parts by weight: 0.1-10 parts of inonotus obliquus mixture and 0.1-10 parts of guaiacum mixture;

wherein the inonotus obliquus mixture comprises the following components in percentage by mass: 60-70% of inonotus obliquus extract, 25-31% of lactobacillus fermentation lysate, 4.1-8.5% of first polyol and 0.2-1.2% of preservative, and the components are weighed according to mass percentage and uniformly mixed to obtain the inonotus obliquus mixture;

The guaiac mixture comprises the following components in percentage by mass: 3-4% of guaiacum extract, 1-10% of second polyol, 0.2-0.8% of antioxidant and the balance of water, and the components are weighed and uniformly mixed according to mass percent to obtain a guaiacum mixture;

The inonotus obliquus extract and the lactobacillus fermentation lysate are prepared by the following steps: crushing inonotus obliquus raw materials, adding lactobacillus for fermentation to obtain fermentation liquor, and carrying out vacuum concentration on the fermentation liquor to obtain a target product;

The guaiacum extract is prepared by the following steps: and sequentially carrying out crushing, alcohol extraction, vacuum concentration and sterilization treatment on the guaiacum raw material to obtain the guaiacum extract.

2. An antiallergic soothing plant composition according to claim 1, characterized in that: the mass ratio of the inonotus obliquus mixture to the guaiac mixture is 1:1.

3. An antiallergic soothing plant composition according to claim 1, characterized in that: the first polyol includes at least one of glycerol and1, 3-propanediol, and the preservative includes at least one of octanoyl hydroxamic acid and1, 2-hexanediol.

4. An antiallergic soothing plant composition according to claim 1, characterized in that: the second polyol comprises one or more of propylene glycol, glycerin, and butylene glycol, and the antioxidant comprises one or more of p-hydroxyacetophenone, ascorbic acid, an ascorbic acid derivative, tocopherol, and tocopheryl acetate.

5. A cosmetic product comprising a base and an active ingredient, characterized in that: the efficacy component is the antiallergic and soothing plant composition of any one of claims 1-4.

6. The cosmetic product according to claim 5, wherein: the plant composition accounts for 0.2-20% of the total mass of the cosmetic.