CN114895047A - Sample analyzer - Google Patents

Abstract

The invention discloses a sample analyzer, which comprises a shell, a separation module, a detection module and a transfer module, wherein the shell is provided with an installation cavity and a sample inlet communicated with the installation cavity, the shell is also provided with a sample inlet table corresponding to the sample inlet, the sample inlet table is used for placing a sample to be detected, the separation module is arranged in the installation cavity, the separation module is provided with a separation cavity, the separation cavity is used for accommodating the sample to be detected, the separation module is used for separating the sample to be detected, the detection module is arranged in the installation cavity and is positioned on one side of the separation module, which is far away from the sample inlet, the detection module is used for detecting the sample to be detected, the transfer module is arranged in the installation cavity, and the transfer module is used for transferring the sample to be detected of the sample inlet table to the separation cavity or the detection module. The invention aims to provide a sample analyzer integrating centrifugal separation and detection, which not only simplifies the manual operation steps, but also effectively reduces the biological safety risk of sample pollution and shortens the detection time.

Description

Sample Analyzer

technical field

The invention relates to the technical field of blood sample detection equipment, in particular to a sample analyzer.

Background technique

Blood is one of the most commonly used samples in clinical tests. Various physiological and pathological information of subjects can be obtained from blood through various detection methods such as biochemistry and immunity, providing a basis for clinical diagnosis and treatment. At present, most of the blood tests need to separate blood components in the blood sample preprocessing stage, and then perform subsequent detection on the separated blood components.

In the related art, the detection equipment does not have a separation function. The separation of blood requires a separate separation mechanism for separation, and the separated serum and plasma are then put into the detection equipment for detection, which not only leads to cumbersome operations, but also increases the risk of sample contamination. Biosecurity risks, while extending the detection time.

SUMMARY OF THE INVENTION

The main purpose of the present invention is to provide a sample analyzer, which aims to provide a sample analyzer that integrates centrifugal separation and detection, which not only simplifies manual operation steps, but also effectively reduces the biological pollution caused by the sample. security risks while reducing detection time.

In order to achieve the above object, the present invention provides a sample analyzer, the sample analyzer includes:

A casing, the casing is provided with an installation cavity and a sample inlet connected to the installation cavity, and the casing is also provided with a sample inlet table corresponding to the sample inlet port, and the sample inlet table is used for placing the sample to be tested ;

A separation module, the separation module is arranged in the installation cavity, the separation module is provided with a separation cavity, the separation cavity is used for accommodating the sample to be tested, and the separation module is used for separation of the sample to be tested;

a detection module, the detection module is arranged in the installation cavity and is located on the side of the separation module away from the sample inlet, and the detection module is used for detecting the sample to be tested; and

A transfer module, the transfer module is arranged in the installation cavity, and the transfer module is used for transferring the sample to be tested in the sample feeding station to the separation cavity or the detection module.

In one embodiment, the transfer module includes:

a first sampling assembly, the first sampling assembly is arranged in the installation cavity and is opposite to the separation module, and the first sampling assembly includes a first frame body, a first drive an assembly and a first sampling needle, the first drive assembly is connected to the first frame body, the first sampling needle is connected to the first drive assembly, and the first drive assembly is used to drive the first a sampling needle reciprocates between the sampling station and the separation chamber to aspirate and transfer the sample to be tested; and

A second sampling assembly, the second sampling assembly is disposed in the installation cavity, the second sampling assembly is opposite to the first sampling assembly and disposed at intervals, and the second sampling assembly includes the second frame body, the second drive assembly and the second sampling needle, the second drive assembly is connected to the second frame body, the second sampling needle is connected to the second drive assembly, the second The driving component is used for driving the second sampling needle to move back and forth between the sample introduction stage or the separation chamber and the detection module to suck and transfer the separated sample to be tested.

In one embodiment, the casing is further provided with a reagent inlet that communicates with the installation cavity, the reagent inlet is disposed adjacent to the second sampling assembly, and the sample analyzer further includes a reagent chamber connected to the reagent chamber. On the casing and at the reagent inlet, the reagent chamber is used to place the reaction reagent.

In one embodiment, the reagent compartment includes:

a movable piece movably connected to the casing and located at the reagent inlet; and

a placing plate, the placing plate is detachably arranged on the movable part, and the placing plate is used for placing the reaction reagent;

Wherein, the movable part drives the placing plate to enter or exit the installation cavity from the reagent inlet, so that the placing plate is located at the position of the second sampling needle between the sample introduction platform and the detection module. a moving path, and the second driving component drives the second sampling needle to move back and forth between the placement tray and the detection module.

In one embodiment, the detection module includes:

a rotary driving member, the rotary driving member is arranged in the installation cavity;

a rotary table, the rotary table is rotatably arranged in the installation cavity and connected with the rotary drive member, and the rotary table is provided with a reaction station and a detection station;

a detection module, the detection module is arranged on one side of the rotary table;

A cup feeding assembly, the cup feeding assembly is arranged in the installation cavity and adjacent to the first sampling assembly, and the cup feeding assembly is provided with a cup placing cavity, a conveying channel and a cup outlet. The two ends are respectively communicated with the cup holding cavity and the cup outlet, and the cup outlet is arranged corresponding to the rotary table;

Wherein, the rotary drive member drives the rotary table to rotate, so that the detection station corresponds to the detection module, and the reaction station corresponds to the cup outlet.

In one embodiment, the casing is further provided with a replacement port communicating with the installation cavity, the replacement port corresponds to the separation module, and the separation module includes:

a third frame body, the third frame body is arranged in the installation cavity and corresponding to the replacement port, and the third frame body is provided with an installation groove;

a separation driving member, the separation driving member is arranged on the side of the third frame body facing away from the installation groove, and the output shaft of the separation driving member penetrates the bottom wall of the installation groove; and

a separation disc, the separation disc is movably arranged in the installation groove, and is detachably connected with the output shaft of the separation drive member, and the separation disc is provided with the separation cavity;

Wherein, the separation driving member drives the separation disc to rotate, so as to separate the samples to be tested in the separation chamber.

In one embodiment, the third frame body includes an installation frame and a separation seat, the installation frame is installed in the installation cavity and is disposed corresponding to the replacement port, the installation frame is provided with a sliding rail, and the separation seat is provided. slidably connected with the sliding rail, the separation seat is provided with the installation groove, and the separation driving member is arranged on the side of the separation seat facing away from the installation groove;

The separation module further includes a replacement driver, the replacement driver is arranged on the mounting frame and connected to the separation seat, and the replacement driver drives the separation seat to drive the separation disc to enter or exit. the installation cavity.

In one embodiment, the casing is further provided with a movable baffle corresponding to the replacement port, and the movable baffle is movably connected with the casing to open or close the replacement port;

And/or, the casing is further provided with a placement rack adjacent to the replacement port, and the placement rack is provided with a placement cavity for placing the separation disk;

And/or, the casing is further provided with a waste port that communicates with the installation cavity, the waste port is arranged adjacent to the replacement port, and corresponds to the detection module, and the sample analyzer further includes a waste material. A collection box, the waste collection box is detachably arranged at the waste port, and is used to collect the waste detected by the detection module.

In one embodiment, the sample to be tested is provided with an identification code, and the sample analyzer further includes a detection piece, the detection piece is set on the casing and is set corresponding to the sample feeding table, and the first The sampling assembly and the second sampling assembly are located on opposite sides of the detection member, and the detection member is used for detecting the identification code of the sample to be tested.

In one embodiment, the sample introduction station is provided with a puncture position and a sample suction position, the puncture position is set corresponding to the first sampling assembly, and the sample suction position is set corresponding to the second sampling assembly.

In one embodiment, the sample introduction station is further provided with a circulating sample introduction channel, and the circulating sample introduction channel extends from the sample suction position to the puncture position;

And/or, the sample introduction station is further provided with an emergency position, and the emergency position is disposed adjacent to the puncture position.

In one embodiment, the sample analyzer further includes a mixing component, and the mixing component includes:

a fixing frame, the fixing frame is arranged in the installation cavity and is arranged adjacent to the injection port;

a mixing driving member, the mixing driving member is arranged on the fixing frame; and

a mixing gripper, the mixing gripper is connected to the output shaft of the mixing driver, and the mixing gripper is provided with a clamping groove;

Wherein, the mixing driving member drives the mixing gripper to clamp the sample to be tested in the clamping groove for mixing.

In one embodiment, the sample analyzer further includes a controller and a display screen disposed in the casing, the display screen is disposed adjacent to the injection port, and the controller is connected to the display screen, the display screen, and the display screen. The separation module, the detection module and the transfer module are electrically connected.

In the sample analyzer of the technical solution of the present invention, an installation cavity is arranged in the casing, so that the separation module, the detection module and the transfer module are installed, fixed and protected by the installation cavity, so as to ensure that the steps of sample introduction, separation and detection are all performed in the installation cavity. In this way, the biosafety risk of sample contamination is effectively reduced; by setting a sample inlet connected to the installation cavity on the casing, and setting a sample inlet station corresponding to the sample inlet, it is convenient to use the sample inlet station to place or store the sample to be tested. At the same time, it is convenient for the transfer module to sample the sample to be tested on the sample injection platform through the sample inlet; by integrating the separation module, the detection module and the transfer module into the installation cavity of the casing at the same time, the sample analyzer can pass While the transfer module realizes sample injection, it is also convenient to use the separation module to centrifuge the samples to be tested placed in the separation chamber, so that the detection module can detect the separated samples to be tested, which simplifies the manual operation steps. And shorten the detection time. It can be understood that by reasonably arranging the separation module, the detection module and the transfer module in the installation cavity of the casing, it is ensured that the volume of the sample analyzer is not increased, and the layout in the installation cavity of the casing is more compact.

Description of drawings

In order to explain the embodiments of the present invention or the technical solutions in the prior art more clearly, the following briefly introduces the accompanying drawings that need to be used in the description of the embodiments or the prior art. Obviously, the accompanying drawings in the following description are only These are some embodiments of the present invention, and for those of ordinary skill in the art, other drawings can also be obtained according to the structures shown in these drawings without creative efforts.

1 is a schematic structural diagram of a sample analyzer according to an embodiment of the present invention;

FIG. 2 is a schematic structural diagram of a sample analyzer from another viewing angle according to an embodiment of the present invention;

FIG. 3 is a schematic structural diagram of the sample analyzer with the casing removed in an embodiment of the present invention;

FIG. 4 is a schematic structural diagram of another view angle of the sample analyzer with the casing removed in an embodiment of the present invention;

FIG. 5 is a schematic structural diagram of the sample analyzer with the casing removed in an embodiment of the present invention;

FIG. 6 is a schematic top-view structural diagram of the sample analyzer with the casing removed according to an embodiment of the present invention.

Description of reference numbers:

label name label name label name 100 Sample Analyzer twenty two Separate seat 413 first sampling needle 1 chassis 221 mounting slot 42 second sampling component 11 mounting cavity twenty four separate platters 421 second frame 12 base 241 Filling position 422 second drive assembly 121 injection station 242 sampling bit 423 second sampling needle 13 side panel 3 Detection module 5 Reagent compartment 131 Injector 31 Rotary drive 51 moving parts 132 Reagent inlet 32 turntable 52 place plate 133 replacement port 33 Detection module 53 Reagents 134 flapper 34 Cup feeding components 6 Test piece 135 waste port 341 cup cavity 7 Mixing components 14 roof 342 delivery channel 71 Fixture 15 Sample to be tested 343 Cup outlet 72 Mixing drive 16 waste collection box 4 transfer module 73 Mixing jaws 2 separate module 41 first sampling component 74 Clamping groove twenty one Mount 411 first frame 81 controller 211 sliding rail 412 first drive assembly 82 display

The realization, functional characteristics and advantages of the present invention will be further described with reference to the accompanying drawings in conjunction with the embodiments.

Detailed ways

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

It should be noted that all directional indications (such as up, down, left, right, front, back, etc.) in the embodiments of the present invention are only used to explain the relationship between various components under a certain posture (as shown in the accompanying drawings). The relative positional relationship, the movement situation, etc., if the specific posture changes, the directional indication also changes accordingly.

At the same time, the meaning of "and/or" or "and/or" in the whole text is that it includes three schemes, taking "A and/or B" as an example, including scheme A, scheme B, or scheme A and B at the same time satisfied plan.

In addition, descriptions such as "first", "second", etc. in the present invention are only for descriptive purposes, and should not be construed as indicating or implying their relative importance or implicitly indicating the number of indicated technical features. Thus, a feature delimited with "first", "second" may expressly or implicitly include at least one of that feature. In addition, the technical solutions between the various embodiments can be combined with each other, but must be based on the realization by those of ordinary skill in the art. When the combination of technical solutions is contradictory or cannot be realized, it should be considered that the combination of such technical solutions does not exist. , is not within the scope of protection required by the present invention.

Blood is one of the most commonly used samples in clinical tests. Various physiological and pathological information of subjects can be obtained from blood through various detection methods such as biochemistry and immunity, providing a basis for clinical diagnosis and treatment. At present, most of the blood tests need to separate blood components in the blood sample preprocessing stage, and then perform subsequent detection on the separated blood components.

In the related art, the detection equipment does not have a separation function, and the separation of blood requires a separate separation mechanism, and the separated serum and plasma are then put into the detection equipment for detection. This increases the manual opening operation, which not only leads to cumbersome operations, but also It increases the biosecurity risk of contamination, the risk of sample misplacement and confusion, and increases the wait and transfer time from the centrifuge to the instrument, thereby extending the total time from receipt of sample to test result.

Based on the above concepts and problems, the present invention provides a sample analyzer 100 . It is understood that the sample analyzer 100 is used to detect blood samples. The blood sample may be one or more of whole blood samples, serum samples, plasma samples, blood cell samples, hemoglobin samples, urine and other body fluids. In this embodiment, the blood sample can be stored or stored in a reaction container, and the reaction container can be a circular tube reaction cup, an inner octagonal circular tube reaction cup, a vacuum blood collection tube, a micro vacuum blood collection tube, a square tube reaction cup, etc., This is not limited. Of course, the reaction vessel includes not only the cuvette for luminescence, but also the cuvette used for several other instruments, such as blood cells, biochemistry, coagulation, etc., that is, the sample analyzer 100 can be applied to the fields of blood cells, biochemistry, coagulation, etc. This is not limited.

It can be understood that the whole blood sample is used as the blood sample to be separated, because the density of the components in the blood sample is greater than that of the plasma or serum components, so the plasma or serum samples can be obtained by centrifugation for further analysis; The test sample is a serum or plasma sample. In this embodiment, the sample 15 to be tested may be one or more of a whole blood sample, a serum sample, a plasma sample, a blood cell sample, and a hemoglobin sample, which is not limited herein.

1 to 6 , in the embodiment of the present invention, the sample analyzer 100 includes a casing 1 , a separation module 2 , a detection module 3 and a transfer module 4 , wherein the casing 1 is provided with The installation cavity 11 is connected to the sample inlet 131 of the installation cavity 11. The casing 1 is also provided with a sample inlet 121 corresponding to the sample inlet 131. The sample inlet 121 is used to place the sample to be tested 15, and the separation module 2 is arranged in the installation cavity. Inside 11, the separation module 2 is provided with a separation cavity, the separation cavity is used to accommodate the sample to be tested 15, the separation module 2 is used to separate the sample to be tested 15, and the detection module 3 is arranged in the installation cavity 11 and is located in the separation module 2. The side facing away from the sample inlet 131, the detection module 3 is used to detect the sample to be tested 15, the transfer module 4 is arranged in the installation cavity 11, and the transfer module 4 is used to transfer the sample to be tested 15 of the sample inlet 121. to the separation chamber or detection module 3.

In this embodiment, the casing 1 is used to install, fix and support the separation module 2, the detection module 3 and the transfer module 4 and other components, that is, the casing 1 is the separation module 2, the detection module 3 and the transfer module Components such as group 4 provide the installation base. It can be understood that, in order to ensure that the samples are not contaminated during the sampling, separation, detection and other processes, the installation cavity 11 of the casing 1 can be selected as a closed space.

It can be understood that, as shown in FIGS. 1 to 6 , the casing 1 includes a base 12 , a side plate 13 and a top plate 14 . The side plate 13 is arranged on the periphery of the base 12 , and the top plate 14 is opposite to the base 12 and away from the side plate 13 . One end of the base 12 is connected, so that the base 12 , the side plate 13 and the top plate 14 are enclosed to form a closed installation cavity 11 . Optionally, the side panel 13 includes a front side panel, a left side panel, a right side panel and a rear side panel, the front side panel, the left side panel, the right side panel and the rear side panel are connected in sequence, and one end is connected to the four The sides are connected, and the other end is connected with the four side plates of the top plate 14 .

In this embodiment, as shown in FIG. 1 to FIG. 6 , the sample inlet 131 is opened on the front side panel of the side panel 13 , and the sample inlet table 121 extends from the base 12 and protrudes from the front side panel of the side panel 13 . It can be understood that the sample introduction table 121 is used for placing the sample 15 to be tested. In order to facilitate the placement of the sample to be tested 15 , the sample introduction table 121 is provided with a placement rack, and the placement rack is provided with a limiting groove for accommodating and limiting the sample to be tested 15 .

It can be understood that, in order to allow the multiple samples to be tested 15 to be tested in sequence, and to facilitate the distinction between undetected samples and detected samples, the sample introduction station 121 includes the to-be-detected area and the inspected area located on both sides of the injection port 131 , and the corresponding inlets. The detection area of the sample port 131. In the present embodiment, the sample introduction table 121 is provided with a drive mechanism for driving the sample to be tested 15 in the area to be inspected to move from the inspection area to the inspected area. 15 The structure of the transfer is not limited here. Optionally, the sample introduction station 121 is provided with a sample injector, and the sample injector is used to implement a mechanism for cyclically injecting the sample to be tested 15 , which is not limited herein.

In this embodiment, as shown in FIGS. 2 to 6 , the separation module 2 is disposed on the base 12 of the casing 1 , and the separation module 2 is provided with a separation cavity for accommodating and separating the sample 15 to be tested. The separation module 2 Used to separate the sample to be tested 15. It can be understood that the separation module 2 can be a structure capable of realizing centrifugal separation of liquids, such as a separator, a separation disc, a centrifugal cup, a centrifugal microfluidic chip, etc., which is not limited herein.

It can be understood that the detection module 3 is arranged on the base 12 and the side plate 13/top plate 14 of the casing 1, and the detection module 3 is used to detect the separated samples to be tested 15 or serum samples, plasma samples, blood cell samples, and hemoglobin samples. One or more of them are tested. In this embodiment, the transfer module 4 can be disposed on the side plate 13/top plate 14 of the casing 1, and is spaced apart from and opposite to the separation module 2 and the detection module 3, so that the transfer module 4 can easily attach the sample injection stage 121 The sample to be tested 15 is transferred to the separation chamber or detection module 3 .

In this embodiment, when the sample to be tested 15 needs to be separated, the transfer module 4 transfers the sample to be tested 15 of the sample feeding station 121 to the separation chamber for centrifugal separation, and after the separation, the transfer module 4 separates the separation chamber The latter sample is transferred to the detection module 3 for detection. Of course, when the sample to be tested 15 does not need to be separated, the transfer module 4 directly transfers the sample to be tested 15 of the sample feeding station 121 to the detection module 3, so that the detection module 3 detects the sample to be tested 15, so that the sample can be analyzed The instrument 100 can be applied to the detection of various samples, improving the versatility.

In the sample analyzer 100 of the present invention, an installation cavity 11 is provided in the casing 1, so that the installation cavity 11 is used to install, fix and protect the separation module 2, the detection module 3 and the transfer module 4, so as to ensure sample injection, separation and detection. The steps are all performed in the installation cavity 11, thereby effectively reducing the biosafety risk of sample contamination. It is convenient to use the sample inlet 121 to place or store the sample to be tested 15, and at the same time, it is convenient for the transfer module 4 to sample the sample to be tested 15 of the sample inlet 121 through the sample inlet 131; The transfer module 4 is also integrated into the installation cavity 11 of the casing 1, so that the sample analyzer 100 can perform sample injection through the transfer module 4, and it is also convenient to use the separation module 2 to test the sample 15 placed in the separation cavity. Centrifugal separation is performed, so that the detection module 3 can detect the separated sample to be tested, which simplifies the manual operation steps and shortens the detection time. It can be understood that by reasonably arranging the separation module 2 , the detection module 3 and the transfer module 4 in the installation cavity 11 of the casing 1 , it is ensured that the volume of the sample analyzer 100 is not increased, so that the installation cavity of the casing 1 is not increased. The layout inside 11 is more compact.

In one embodiment, the transfer module 4 includes a first sampling assembly 41 and a second sampling assembly 42 , wherein the first sampling assembly 41 is disposed in the installation cavity 11 and is opposite to the separation module 2 . It includes a first frame body 411 , a first drive assembly 412 and a first sampling needle 413 arranged in the casing 1 , the first drive assembly 412 is connected to the first frame body 411 , and the first sampling needle 413 is connected to the first drive assembly 412 , the first drive assembly 412 is used to drive the first sampling needle 413 to move back and forth between the sample introduction stage 121 and the separation cavity to suck and transfer the sample 15 to be tested. The second sampling assembly 42 is arranged in the installation cavity 11, and the second sampling The assembly 42 is opposite to and spaced apart from the first sampling assembly 41 . The second sampling assembly 42 includes a second frame 421 , a second driving assembly 422 and a second sampling needle 423 disposed in the casing 1 . The second driving assembly 422 is connected to the The second frame 421 and the second sampling needle 423 are connected to the second driving assembly 422 , and the second driving assembly 422 is used to drive the second sampling needle 423 to move back and forth between the sampling stage 121 or the separation chamber and the detection module 3 to Aspirate and transfer the separated sample to be tested 15 .

In this embodiment, as shown in FIGS. 3 to 6 , the first sampling assembly 41 and the second sampling assembly 42 of the transfer module 4 are arranged in the installation cavity 11 of the casing 1 . Optionally, the first sampling assembly 41 and the second sampling assembly 42 are respectively fixed on the left side plate and the right side plate of the side plate 13 , so that the first sampling assembly 41 and the second sampling assembly 42 are located on the side of the separation module 2 . On the opposite sides, the first sampling assembly 41 and the second sampling assembly 42 can respectively inject different samples. Of course, the second sampling assembly 42 is located on the right side of the separation module 2, and the first sampling assembly 41 may be located above the separation module 2, or may be disposed to the left or the right, which is not limited herein.

It can be understood that the first frame body 411 of the first sampling assembly 41 is fixed to the left side plate of the side plate 13 , so as to guide the base for installing, fixing and moving the first driving assembly 412 and the first sampling needle 413 . In this embodiment, the first frame body 411 is provided with a slide rail, the slide rail extends from the sample inlet 131 to the detection module 3, the first drive assembly 412 is slidably connected to the slide rail, and the first drive assembly 412 can drive the mold Group, in order to facilitate sampling and stakeout, the first drive assembly 412 can drive the first sampling needle 413 to move in two-dimensional or three-dimensional directions, such as the two-dimensional direction of the X-axis and the Z-axis or the X-axis, Y-axis and Z-axis. The three-dimensional direction is not limited here. Of course, the first frame body 411 may be a bracket structure installed or provided with structures such as installation grooves, guide rails, and screw rods. Optionally, the first frame body 411 and the side plate 13 of the casing 1 may be detachably connected or integrally connected, which is not limited herein.

In this embodiment, the first sampling needle 413 may be a puncturing whole blood sampling needle, a two-dimensional needle mechanism used to remove a whole blood sample after puncturing a test tube, and the sample to be tested 15 may be a whole blood capped sample with a cap of the test tube The sealed whole blood collection tube is sampled on the sample introduction platform 121, and the whole blood sample is removed after puncturing with a puncture sampling needle capable of two-dimensional movement.

It can be understood that the second frame body 421 of the second sampling assembly 42 is fixed to the right side plate of the side plate 13 , so as to guide the base for installing, fixing and moving the second driving assembly 422 and the second sampling needle 423 . In this embodiment, the second frame body 421 is provided with a slide rail, the slide rail extends from the sample inlet 131 to the detection module 3, the second drive assembly 422 is slidably connected to the slide rail, and the second drive assembly 422 can drive the mold Group, in order to facilitate sampling and stakeout, the second drive assembly 422 can drive the second sampling needle 423 to move in two-dimensional or three-dimensional directions, such as the two-dimensional directions of the X-axis and the Z-axis or the X-axis, Y-axis and Z-axis. The three-dimensional direction is not limited here. Of course, the second frame body 421 may be a bracket structure installed or provided with structures such as installation grooves, guide rails, and screw rods. Optionally, the second frame body 421 and the side plate 13 of the casing 1 may be connected in a detachable manner or integrally connected, which is not limited herein.

In this embodiment, the second sampling needle 423 may be a reagent needle, which is used to aspirate a sample and fill it into the sample filling position of the detection module 3 . The sample to be tested 15 can also be a non-puncture, open-capped serum or plasma sample. The open serum and plasma samples without a cap are placed on the sample injection platform 121, and the samples are aspirated and injected into the detection module 3 by a three-dimensional sample and a reagent needle. Add sample position.

It can be understood that the sample introduction table 121 is used to store the sampling tube containing the sample to be tested 15. The sample introduction table 121 can be provided with a detachable sampling rack, and the sampling rack is provided with one or more limit holes or limit grooves, each At least a part of the structure of a sampling tube is accommodated and limited in the limiting hole or the limiting groove, so as to realize the reliable fixing of the sampling tube on the sample adding rack, and at the same time, it is convenient to automatically remove the empty sampling tube through mechanical devices such as mechanical arms. Transfer the sampling tube outwards to wait for sampling, or automatically place the sampling tube that collects the blood sample into the limit hole or limit groove of the sample adding rack, so as to improve the transfer efficiency of the sampling tube on the sample introduction platform 121 .

When sampling, the sampling rack is detached from the sampling station 121 and transferred to the sampling point. After the sampling of each sampling tube is completed, the sampling tube from which the blood sample has been collected is placed in a sampling rack, and then the sampling rack is transferred and fixed on the sampling platform 121 for sampling. During sample injection, the first sampling needle 413/second sampling needle 423 of the transfer module 4 moves to the top of the sampling table 121, and sucks a blood sample in a sampling tube, and then the first sampling needle 413/second sampling needle 423 moves Go to the top of the separation module 2/detection module 3, and add the blood sample to the sample addition position of a separation chamber/detection module 3. Repeat the above steps to add blood samples in different sampling tubes to different separation chambers /In the sample adding position of the detection module 3, automatic feeding of multiple blood samples is realized, and the sample adding efficiency of the sample analyzer 100 is improved.

In one embodiment, the casing 1 is further provided with a reagent inlet 132 that communicates with the installation cavity 11 . The reagent inlet 132 is disposed adjacent to the second sampling assembly 42 , and the sample analyzer 100 further includes a reagent chamber 5 , which is connected to the casing 1 . , and is located at the reagent inlet 132 , and the reagent chamber 5 is used to place the reaction reagent 53 .

In this embodiment, as shown in FIG. 1 , FIG. 3 , FIG. 5 and FIG. 6 , a reagent inlet 132 is opened on the right side panel of the side panel 13 of the casing 1 , and the reagent chamber 5 is provided to facilitate the reagent chamber 5 Entering or exiting the installation cavity 11 through the reagent inlet 132 , it is convenient for the second sampling needle 423 of the second sampling assembly 42 to transfer the reaction reagent 53 of the reagent chamber 5 to the detection module 3 , so that the sample to be tested 15 / the separated sample to be tested The test sample 15 reacts with the reaction reagent 53 to facilitate the detection by the detection module 3 .

In one embodiment, the reagent chamber 5 includes a movable member 51 and a placing tray 52. The movable member 51 is movably connected to the casing 1 and is located at the reagent inlet 132. The placing tray 52 is detachably provided on the movable member 51, and the placing tray 52 It is used to place the reaction reagent 53; wherein, the movable member 51 drives the placing plate 52 to enter or exit the installation cavity 11 from the reagent inlet 132, so that the placing plate 52 is located between the second sampling needle 423 and the sample injection platform 121 and the detection module 3. and the second driving component 422 drives the second sampling needle 423 to move back and forth between the placement tray 52 and the detection module 3 .

It can be understood that the reagent inlet 132 on the right panel is adjacent to the base 12 , and the movable member 51 of the reagent compartment 5 is movably connected to the base 12 of the casing 1 . Of course, in order to facilitate automatic entry into or exit from the installation cavity 11 , the reagent chamber 5 also includes a driving member disposed on the base 12 , and the output shaft of the driving member is connected to the movable member 51 , so that the movable member 51 can drive the placing tray 52 from the reagent inlet 132 to the driving member 51 . Enter or exit the mounting cavity 11 .

In this embodiment, the placing plate 52 is provided with a groove structure for installing, fixing and limiting the reaction reagent 53 . In order to carry and replace the placing tray 52 conveniently, the placing tray 52 is detachably provided on the movable member 51 . For example, the placing tray 52 and the movable member 51 may be connected in a detachable connection manner such as snap connection, plug fit, screw connection or pin connection.

It can be understood that, in order to improve the aesthetics of the casing 1 and avoid contamination of the reaction reagent 53 , the casing 1 further includes a compartment door rotatably connected to the right side panel of the side panel 13 , and the compartment door can open or close the reagent inlet 132 . The placement tray 52 can optionally be a plastic holder for placing the test tubes. As shown in FIGS. 1 , 3 , 5 and 6 , the reagent compartment 5 has a position where the tray 52 is pushed into the installation cavity 11 from the reagent inlet 132 after it is installed, and the tray 52 is pulled out from the reagent inlet 132 after the tray 52 is used up. The position outside the installation cavity 11 is not limited here.

In one embodiment, the detection module 3 includes a rotary driving member 31 , a rotary table 32 , a detection module 33 and a cup feeding assembly 34 , the rotary driving member 31 is arranged in the installation cavity 11 , and the rotary table 32 is rotated and arranged in the installation cavity 11 . , and is connected with the rotary drive member 31, the rotary table 32 is provided with a reaction station and a detection station, the detection module 33 is provided on one side of the rotary table 32, and the cup feeding assembly 34 is provided in the installation cavity 11, adjacent to the first sampling The component 41 is provided, and the cup feeding component 34 is provided with a cup cavity 341, a conveying channel 342 and a cup outlet 343. The two ends of the conveying channel 342 are respectively connected with the cup cavity 341 and the cup outlet 343, and the cup outlet 343 corresponds to the rotary table. 32 is provided; wherein, the rotary drive member 31 drives the rotary table 32 to rotate, so that the detection station corresponds to the detection module 33 , and the reaction station corresponds to the cup outlet 343 .

In this embodiment, as shown in FIG. 3 to FIG. 6 , the detection module 33 includes a liquid circuit component, a cleaning plate, an incubation plate, a preheating component, a detector, an incubation detection module, a mixing and cleaning magnetic separation component, and the like. The components include various pumps, valves, pipelines, etc. of the liquid circuit system in the detection module 3. The cleaning disk is used to clean the magnetic beads and immune products in the reaction cup, and the incubation disk is used for the reaction cup to contain the sample to be tested 15 and the reaction reagents. 53 Reaction, the preheating component is used to heat or preheat the substrate reagent, and add the heated substrate reagent to the reaction cup to avoid affecting the accuracy of the detection result due to temperature differences. The detector is a component for photometric detection of the reacted sample reagent mixture, and the incubation detection module is used to add reagents, mix, wash, magnetically separate, add substrate, and photometrically to the centrifuged plasma samples. The detection component, the mixing and cleaning magnetic separation component is a component that separates the solid phase objects of the mixture after the reaction.

It can be understood that the cuvette is a disposable container for accommodating the mixture of the sample to be tested 15 and the reaction reagent 53 and performing photometric detection. After the detection is completed, the cuvette will discard the discarded cuvette from the throwing position. In this embodiment, the detection module 3 also has a cup-shifting gripper assembly, which is used to transfer the reaction cup between the two circles of the incubation detection module and the cup-throwing position, and also has a mixing function. Of course, the detection module 3 also has a cleaning position, and the cleaning position is used for cleaning the first sampling needle 413/second sampling needle 423.

In this embodiment, the rotary drive member 31 and the rotary table 32 of the detection module 3 are installed on the base 12 of the casing 1, and are located on the side of the separation module 2 facing away from the sample inlet 131. The rotary table 32 can be The carrier structure used to hold or place the reaction cup, the driving member 31 can be a driving motor or a rotary motor, etc., and the rotary driving member 31 drives the rotary table 32 to rotate, so that the detection station corresponds to the detection module 33, and the reaction station It corresponds to the cup outlet 343 and is not limited here.

It can be understood that the detection module 33 automatically detects the samples to be detected separated by the separation module 2 by means of optics, electrochemistry, etc., so as to obtain the physiological and pathological information of the corresponding subjects and provide a basis for clinical diagnosis and treatment.

In this embodiment, as shown in FIGS. 3 to 6 , the cup feeding assembly 34 is provided so that it is provided on the left side panel of the side panel 13 of the casing 1 and is disposed adjacent to the first sampling assembly 41 , so as to realize the installation. The reasonable arrangement of the components in the cavity 11 not only improves the space utilization rate, but also reduces the volume of the casing 1 . It can be understood that the cup feeding assembly 34 includes a storage box, a transmission member and a cup dividing member. The storage box of the cup feeding assembly 34 is provided with a cup-receiving cavity 341 for storing the reaction cups, and the transmission member is provided with a conveying device that communicates with the cup-receiving cavity 341. The channel 342, such as a conveyor belt or a conveyor belt, is provided with a cup outlet 343 that communicates with the delivery channel 342, so that the cuvette in the cup cavity 341 can be transported to the cup outlet 343 through the conveying channel 342, and via The cup transfer gripper assembly of the detection module 3 transfers the cuvette at the cup outlet 343 to the reaction station, so that the first sampling needle 413/the second sampling needle 423 will transfer the sample to be tested 15/separated sample to be tested 15 and the reaction reagent 53 are transferred to the reaction cup for reaction. After the reaction is completed, the rotary table 32 is driven to rotate through the driving member 31, so that the reaction cup is transferred from the reaction station to the detection station, and is detected through the detection module 33. After the end, the cuvette is discarded from the throwing position via the cup transfer gripper assembly.

It can be understood that the cup feeding assembly 34 is used for feeding the reaction cups into the detection module 3 one by one, and the conveying channel 342 is used for feeding the reaction cups one by one from the cup placing cavity 341 into the slideway of the incubation detection module.

In one embodiment, the casing 1 is further provided with a waste port 135 that communicates with the installation cavity 11 . The waste port 135 is disposed adjacent to the replacement port 133 and corresponds to the detection module 3 . The sample analyzer 100 further includes a waste collection box 16 . , the waste collection box 16 is detachably arranged at the waste port 135 for collecting the waste detected by the detection module 3 .

In this implementation, as shown in FIGS. 2 and 4 , a waste collection box 16 is provided on the left side panel of the side panel 13 of the cabinet 1 by providing a waste material port 135 and a waste collection box 16 at the waste material port 135 . 16 Collect discarded or used cuvettes. It can be understood that the waste port 135 corresponds to the cup throwing position of the detection module 3 .

In order to facilitate recycling and timely cleaning, the waste collection box 16 is detachably disposed at the waste port 135. For example, the waste collection box 16 can be connected by means of snap connection, plug fit, screw connection or pin connection. Of course, the waste collection box 16 can also be disposed at the waste port 135 by adopting a drawer structure, which is not limited herein.

In one embodiment, the casing 1 is further provided with a replacement port 133 that communicates with the installation cavity 11. The replacement port 133 corresponds to the separation module 2, and the separation module 2 includes a third frame body, a separation driver and a separation disc 24. The third frame body is arranged in the installation cavity 11 and corresponding to the replacement port 133 , the third frame body is provided with the installation groove 221 , and the separation driver is arranged on the side of the third frame body that faces away from the installation groove 221 . The output shaft penetrates the bottom wall of the installation slot 221, the separation disc 24 is movably arranged in the installation slot 221, and is detachably connected with the output shaft of the separation drive member, and the separation disc 24 is provided with a separation cavity; wherein, the separation drive member drives the separation The disk 24 is rotated to separate the samples to be tested 15 in the separation chamber.

In this embodiment, as shown in FIGS. 2 to 6 , the replacement port 133 is arranged on the left side panel of the side panel 13 of the casing 1 , and the third frame of the separation module 2 is arranged on the base 12 of the casing 1 . , and is arranged adjacent to the left side plate, and the third frame body is used to install and fix the separation drive member and the separation disc 24 and other components. It can be understood that the installation groove 221 is provided in the third frame body, so that the installation groove 221 is used to realize the limit installation of the separation disk 24. The separation disc 24 placed in the installation slot 221 is connected to the output shaft of the separation driving member, so that the separation driving member can be used to drive the separation disc 24 to rotate to realize centrifugal separation.

It can be understood that, as shown in FIG. 2 to FIG. 6 , the separation disc 24 is provided with a sample adding position 241 and a sampling position 242 arranged at intervals, and the separation disc 24 is also provided with a separation connecting the sample adding position 241 and the sampling position 242. cavity. In this embodiment, the first sampling needle 413 of the first sampling assembly 41 transfers the sample to be tested 15 from the sampling stage 121 to the sampling position 241 , and the separation disc 24 is driven to rotate by the separation driving member to drive the separation disc The blood sample in the upper separation chamber 24 is centrifuged under the rotating centrifugal force, so that the blood sample added to the sample addition position 241 flows into the separation chamber, and the blood cell components and the plasma or serum components are separated in the separation chamber. the plasma or serum sample and the separated blood cell sample, so that the separated sample is transferred by the second sampling needle 423 of the second sampling assembly 42 to the separated sample to be tested 15 from the sampling position 242 to the reaction of the detection module 3 inside the cup.

Optionally, the horizontal setting scheme of the separation disc 24 with smoother rotation and better centrifugation consistency of blood samples in each separation chamber is the preferred setting scheme, and the separation driving member includes, but is not limited to, a motor or a rotary cylinder.

It can be understood that the separation chamber is used to achieve the separation of plasma or serum components and blood cell components in the blood sample, and the separation chamber is arranged along the center of the separation disc 24 toward the outer edge of the separation disc 24, for example, when the separation disc 24 is circular In structure, the separation chamber is arranged along the radial direction of the separation disc 24; for another example, the blood sample separation chamber is radially arranged from the center of the separation disc 24 to the outer edge of the separation carrier. The arrangement of the separation chamber can make full use of the rotational centrifugal force of the separation disc 24, so that the plasma or serum components and blood cell components in the blood sample in the separation chamber can be centrifuged in a shorter time, thereby improving the efficiency of blood sample separation. Wherein, the separation cavity may be a channel structure or a cavity structure.

In this embodiment, as shown in FIGS. 2 to 6 , the separation disc 24 is provided with a plurality of sample adding positions 241 and sampling positions 242 , the plurality of sample adding positions 241 are arranged in a ring, and the plurality of sampling positions 242 are arranged in a ring , and is located outside the plurality of sample adding positions 241 , and the plurality of sample adding positions 241 and the plurality of sampling positions 242 are in one-to-one correspondence with each other through a plurality of separation cavities.

It can be understood that the blood sample is added into the separation chamber through the sample adding position 241, so that the separation driving member drives the separation disc 24 to rotate, so that under the action of the rotating centrifugal force, the blood cell components with higher density are more exposed to the blood cells than the plasma or serum components. Due to the large centrifugal force, after the blood cell components are separated from the plasma or serum components, the blood cell components displace the plasma or serum components, so that the plasma or serum components remain in the local space of the separation chamber near the sample loading position 241, and the separated blood cell components are It remains in the local space of the separation chamber away from the sample loading position 241 . Plasma or serum components and blood cell components are accommodated in different local spaces of the separation chamber to realize the separation of plasma or serum components and blood cell components in the blood sample. After the above separation procedure, the second sampling component 42 extracts the plasma or serum sample in the separation chamber through the sampling position 242, so as to realize the automatic addition, separation, and sampling processing of the blood sample through the above process, thereby improving the efficiency of blood sample processing.

The sample analyzer 100 can accommodate plasma or serum components and blood cell components in different local spaces of the separation chamber, so as to realize the separation of plasma or serum components and blood cell components in the blood sample. The separation disc 24 can accommodate the separated plasma or serum samples and blood cell samples in different cavity spaces in the separation chamber, and the plasma or serum samples and blood cell samples are housed in separate spaces, and the plasma in the separation chamber can be extracted through the sampling position 242 Or serum samples are not easily extracted into blood cell samples by mistake, which can ensure the purity of the extracted plasma or serum samples and reduce the accuracy requirements of the sampling operation. At the same time, the separation module 2 can also achieve the above-mentioned separation and storage process of blood cell components and plasma or serum components for trace blood samples, without the need to collect a large number of blood samples, which can reduce the amount of blood samples used for testing, and the separation effect is good.

In one embodiment, the third frame body includes an installation frame 21 and a separation seat 22. The installation frame 21 is arranged in the installation cavity 11 and is disposed corresponding to the replacement port 133. The installation frame 21 is provided with a sliding rail 211, and the separation seat 22 and the sliding The rails 211 are slidably connected, the separation seat 22 is provided with a mounting groove 221, and the separation driving part is arranged on the side of the separation seat 22 that faces away from the installation groove 221; It is connected with the separation seat 22 , and the replacement driver drives the separation seat 22 to drive the separation disc 24 into or out of the installation cavity 11 from the replacement port 133 .

In this embodiment, as shown in FIG. 2 to FIG. 6 , the third frame body is provided as the mounting frame 21 and the separation seat 22 , so that the mounting frame 21 is arranged on the base 12 of the cabinet 1 and is arranged adjacent to the left side panel , and use the mounting frame 21 to install and fix the separation seat 22 , the separation drive member and the separation disc 24 and other components.

It can be understood that the installation groove 221 is provided in the separation seat 22, so that the installation groove 221 is used to realize the limit installation of the separation disk 24, and the separation driving member is arranged on the side of the separation seat 22 that faces away from the installation groove 221, so that The output shaft of the separation driver penetrates the bottom wall of the installation slot 221, so that the separation disc 24 placed in the installation slot 221 is conveniently connected to the output shaft of the separation driver, so that the separation driver can be used to drive the separation disc 24 to rotate to achieve centrifugal separation.

In this embodiment, as shown in FIGS. 2 to 6 , by arranging the sliding rail 211 and replacing the driving member on the mounting frame 21 , the separation seat 22 is slidably connected with the sliding rail 211 , so that the separation seat 22 is driven by the replacement driving member The separating disc 24 is driven to enter or exit the installation cavity 11 from the replacement port 133 , so as to facilitate the replacement of the separating disc 24 .

In one embodiment, the casing 1 is further provided with a movable baffle 134 corresponding to the replacement port 133 , and the movable baffle 134 is movably connected with the casing 1 to open or close the replacement port 133 . It can be understood that, after the separation disc 24 is replaced, the separation seat 22 is driven by the replacement driver to drive the separation disc 24 from the replacement port 133 into the installation cavity 11, and the movable baffle 134 is used to cover the replacement port 133. , to ensure the airtightness of the installation cavity 11, so as to ensure that the sample is not contaminated.

It can be understood that the movable baffle 134 is rotatably connected to the base 12 of the casing 1, for example, connected by a hinge, a hole-shaft connection or other rotational connection, which is not limited herein.

Of course, the replacement port 133 includes two openings arranged at intervals, and an opening of the replacement port 133 corresponds to the separation disc 24 . Another opening of the replacement port 133 is located below the corresponding opening of the separation disc 24, and the movable baffle 134 is disposed corresponding to the opening to facilitate opening and replacement of the substrate reagent, which is not limited herein.

In one embodiment, the casing 1 is further provided with a placement rack adjacent to the replacement port 133 , and the placement rack is provided with a placement cavity for placing the separation disk 24 . It can be understood that, with this arrangement, it is convenient for the user to install the new separation disk 24 to be replaced in the installation groove 221 of the separation seat 22 directly from the placing rack, thereby improving convenience.

In one embodiment, the sample 15 to be tested is provided with an identification code, and the sample analyzer 100 further includes a detection part 6 , which is arranged on the casing 1 and corresponding to the sample feeding table 121 , and is used for detecting the detection part 6 . Identification code for sample 15.

In this embodiment, as shown in FIGS. 1 to 6 , by setting an identification code on the sample to be tested 15 , the identification code can be used to distinguish whether the test tube containing the sample to be tested 15 is a capped test tube or an uncapped test tube, so that It is used to distinguish the types of the samples 15 to be tested, so that the sample analyzer 100 performs detection according to different samples. It can be understood that the detection element 6 can be a barcode scanner, which is used to scan the identification code or barcode affixed on the test tube.

It can be understood that when the biochemical analyzer 100 is running, the controller 81 controls the detection element 6 to detect the identification code on the sample 15 to be tested. The different identification codes are sampled separately. In this embodiment, the detection member 6 may be disposed on the left or right side of the first sampling assembly 41 and the second sampling assembly 42 . Of course, in other embodiments, the first sampling assembly 41 and the second sampling assembly 42 may also be located on opposite sides of the detection member 6 , and at this time, the first sampling assembly 41 and the second sampling assembly 42 are still being detected by the detection member 6 . After the identification code on the sample 15 to be tested, sampling is performed according to different identification codes.

In one embodiment, the sample introduction station 121 is provided with a puncture position and a sample suction position, the puncture position is set corresponding to the first sampling assembly 41 , and the sample suction position is set corresponding to the second sampling assembly 42 .

In this embodiment, the sample introduction station 121 is provided with a plurality of different areas. For example, the sample introduction station 121 is provided with a puncture position corresponding to the first sampling assembly 41 , and the sample introduction station 121 is disposed with a sample suction position corresponding to the second sampling assembly 42 . It can be understood that the detection element 6 can perform detection according to the type of the test tube of the sample 15 to be tested, so as to distinguish whether the test tube containing the sample to be tested 15 is a test tube with a cap or a test tube without a cap.

It can be understood that the sample introduction table 121 is provided with a driving mechanism for driving the transfer of the sample to be tested 15. When the detector 6 detects that the test tube of the sample to be tested 15 is a capped test tube, the driving mechanism transfers the sample to be tested 15 to the puncture position. , which is sampled or transferred by the first sampling component 41 . When the detection element 6 detects that the test tube of the sample to be tested 15 is an uncapped test tube, the driving mechanism transfers the sample to be tested 15 to the suction position, and the second sampling assembly 42 performs sampling or transfer.

Optionally, the driving mechanism may be a conveyor belt, a conveying mechanism or other structures capable of transferring the sample 15 to be tested, which is not limited herein. Optionally, the sample introduction station 121 is provided with a sample injector, and the sample injector is used to implement a mechanism for cyclically injecting the sample to be tested 15 , which is not limited herein.

In one embodiment, the sample introduction station 121 is further provided with a circulating sample introduction channel, and the circulating sample introduction channel extends from the sample suction position to the puncture position. It can be understood that, by setting the circulating sampling channel on the sampling platform 121 , the circulating sampling channel can be used to realize the transfer and circulation of different samples to be tested 15 . In this embodiment, the drive mechanism in the sample introduction station 121 transfers the sample to be tested 15 in the capped test tube from the sample suction position to the puncture position through the circulating sample introduction channel.

In one embodiment, the sample introduction station 121 is further provided with an emergency position, and the emergency position is set adjacent to the puncture position. It can be understood that by setting the emergency position, the insertion detection of the sample to be tested 15 can be realized by using the emergency position, so that the sample detection can be performed as soon as possible.

In this embodiment, structures such as a placing rack or a test tube rack for placing or fixing the sample to be tested 15 are respectively provided on the sample introduction station 121 corresponding to the puncture position, the sample suction position and the emergency position, which are not limited herein.

In one embodiment, the sample analyzer 100 further includes a mixing assembly 7. The mixing assembly 7 includes a fixing frame 71, a mixing driving member 72 and a mixing clamping jaw 73. The fixing frame 71 is arranged in the installation cavity 11 and is adjacent to the fixing frame 71. The sample inlet 131 is provided, the mixing driving member 72 is set on the fixing frame 71, the mixing clamping jaw 73 is connected to the output shaft of the mixing driving member 72, and the mixing clamping jaw 73 is provided with a clamping groove 74; The component 72 drives the mixing jaw 73 to clamp the sample 15 to be tested in the clamping groove 74 for mixing.

In this embodiment, by disposing the mixing component 7, the sample to be tested 15 on the sample introduction stage 121 can be mixed uniformly by the mixing component 7, so as to improve the detection accuracy. It can be understood that the mixing driving member 72 may be a structure such as a driving motor, a rotating motor, or a rotating cylinder, which is not limited herein. Optionally, the mixing gripper 73 may be a gripper cylinder or a mechanical gripper, which is not limited herein.

In one embodiment, the sample analyzer 100 further includes a controller 81 and a display screen 82 disposed in the casing 1 , the display screen 82 is disposed adjacent to the injection port 131 , the controller 81 is connected to the display screen 82 , the separation module 2 , and the detection screen 82 . The module 3 and the transfer module 4 are electrically connected.

In this embodiment, as shown in FIG. 1 to FIG. 4 , the controller 81 may be a control center or a circuit board or a control board integrated with a control program. The controller 81 communicates with the display screen 82, The separation module 2 , the detection module 3 and the transfer module 4 are electrically connected.

It can be understood that the controller 81 and the display screen 82 , the separation and replacement drivers of the separation module 2 , the rotation driver of the detection module 3 , the detection module 33 and the cup feeding assembly, and the first sampling of the transfer module 4 The component 41 and the second sampling component 42 are electrically or signally connected. The display screen 82 is used to display the start and end information of the separation module 2, the detection information of the detection module 3, and the sample addition information of the transfer module 4, etc., which are not limited herein.

In this embodiment, the side plate 13 further includes a front side plate, the front side plate is rotatably connected to the left side plate or the right side plate, and the front side plate is provided with a sample inlet 131; the biochemical analyzer 100 also includes a front side plate. The display screen 82 on the side facing away from the installation cavity 11, the display screen 82 is arranged at intervals from the sample inlet 131, and is electrically connected to the controller 81, and the display screen 82 is electrically connected to the separation module 2, the detection module 3 and the transfer module 4. connect. It can be understood that the front side panel is rotatably connected with the left side panel or the right side panel, so that the display screen 82 disposed on the front side panel is rotated and opened with the front side panel, which is convenient for maintenance.

The sample analyzer 100 works as follows:

1. The user puts the test tubes and test tube racks containing whole blood samples on the sample injection station 121. When the sample injection station 121 does not cycle samples, it can load 5 rows of test tube racks and 25 test tubes; when the samples are cycled, it can load 10 test tubes. Row 50 samples. The sample introduction station 121 sends the test tubes one by one to the detection position of the test tube corresponding to the detection part 6, and the detection part 6 detects whether the test tube exists. Lift and mix, then move to the puncture position, pierce the cap of the test tube with the two-dimensional needle 413 of the first sampling assembly 41, suck out the whole blood sample and move it to the separation disk 24 of the separation module 2 for sample loading Bit 241 goes into the separation chamber.

2. After the puncture sample needle of the first sampling needle 413 injects the whole blood sample into the separation disc 24, the separation drive member drives the separation disc 24 to rotate and centrifuge at a high speed, and the second sampling needle 423 of the second sampling assembly 42 on the right side The three-dimensional reagent sample needle fills the centrifuged plasma sample into the sample and reagent addition hole, and the reaction cup pushed out by the cup feeding assembly 34 is located under the hole.

3. It should be noted that when the test tube and the cap of the test tube are detected with or without the cover, it is an open non-whole blood sample, such as plasma and serum samples, the above sample aspiration process can be changed to non-mixed, non-homogeneous Puncture and suction, and in the non-puncture, uncapped serum and plasma sample suction position, that is, the second sampling needle 423 of the second sampling assembly 42 directly sucks the serum and plasma samples and adds them to the incubation detection module. The sample and reagent hole position.

4. The three-dimensional reagent sample needle of the second sampling needle 423 sucks various reaction reagents 53 of the reagent chamber 5 and injects them into the reaction cup; Magnetic separation and injection of substrate holes; after the reaction is completed, the reaction cup is removed to the throwing position for throwing the cup to complete the detection.

The above 1 and 2 are the sample adding process of whole blood samples; 3 is the sample adding process of non-whole blood samples such as serum and plasma. The sample analyzer 100 is a model capable of simultaneously supporting samples such as whole blood, serum, and plasma.

It can be understood that in some embodiments of the present application, the sample analyzer 100 may be a non-whole blood sample analyzer that only supports serum and plasma detection and does not have the functions of mixing and whole blood puncture and aspiration; in other embodiments Among them, the sample analyzer 100 can be a whole blood sample analyzer with mixing and puncture sampling functions that supports whole blood detection. Through the mixing and centrifugation in the machine, the operation of centrifuging the whole blood sample needs to be eliminated by the user. It saves labor and avoids cumbersome operations; at the same time, it can avoid the risk of biosafety from opening the lid outside the machine; it can shorten the waiting and transfer time from the centrifuge to the instrument, and improve the speed of emergency samples; reduce the transfer of sequential samples on the centrifuge, Reduce the risk of sample confusion; and the left and right size of the whole machine is greatly reduced compared to other instruments, saving space and reducing weight; at the same time, it can avoid the vibration and noise of the centrifuge.

The above descriptions are only optional embodiments of the present invention, and are not intended to limit the scope of the present invention. Under the conception of the present invention, the equivalent structural transformations made by the contents of the description and drawings of the present invention, or the direct/indirect application Other related technical fields are included in the scope of patent protection of the present invention.

Claims (13)

1. A sample analyzer, comprising:

the sample injection device comprises a shell, a sample injection platform and a sample injection device, wherein the shell is provided with an installation cavity and a sample injection port communicated with the installation cavity, and the shell is also provided with the sample injection platform corresponding to the sample injection port and used for placing a sample to be detected;

the separation module is arranged in the installation cavity, is provided with a separation cavity, and is used for accommodating the sample to be detected and separating the sample to be detected;

the detection module is arranged in the installation cavity and is positioned on one side of the separation module, which is far away from the sample inlet, and the detection module is used for detecting the sample to be detected; and

the transfer module is arranged in the installation cavity and used for transferring the sample to be detected of the sample feeding table to the separation cavity or the detection module.

2. The sample analyzer of claim 1, wherein the transfer module comprises:

the first sampling assembly is arranged in the installation cavity and is opposite to the separation module, the first sampling assembly comprises a first frame body arranged on the shell, a first driving assembly and a first sampling needle, the first driving assembly is connected to the first frame body, the first sampling needle is connected with the first driving assembly, and the first driving assembly is used for driving the first sampling needle to reciprocate between the sample inlet table and the separation cavity so as to suck and transfer the sample to be detected; and

the second sampling subassembly, the second sampling subassembly is located the installation intracavity, the second sampling subassembly with first sampling subassembly is relative and the interval sets up, the second sampling subassembly is including locating second support body, second drive assembly and the second sampling needle of casing, the second drive assembly connect in the second support body, the second sampling needle with the second drive assembly is connected, the second drive assembly is used for driving the second sampling needle is in advance appearance platform or the separation chamber with reciprocating motion is in order to absorb and shift between the detection module after the sample that awaits measuring.

3. The sample analyzer of claim 2 wherein the housing further defines a reagent inlet in communication with the mounting chamber, the reagent inlet being disposed adjacent the second sampling assembly, the sample analyzer further comprising a reagent cartridge coupled to the housing and positioned at the reagent inlet, the reagent cartridge being configured to receive a reagent.

4. The sample analyzer of claim 3, wherein the reagent cartridge comprises:

the movable piece is movably connected to the machine shell and is positioned at the reagent inlet; and

the placing disc is detachably arranged on the moving part and used for placing reaction reagents;

the moving part drives the placing disc to enter or exit from the reagent inlet to enable the placing disc to be located on a moving path of the second sampling needle between the sample feeding table and the detection module, and the second driving assembly drives the second sampling needle to move back and forth between the placing disc and the detection module.

5. The sample analyzer of claim 2, wherein the detection module comprises:

the rotary driving piece is arranged in the mounting cavity;

the rotating table is rotatably arranged in the mounting cavity and is connected with the rotary driving piece, and the rotating table is provided with a reaction station and a detection station;

the detection module is arranged on one side of the rotating platform;

the cup feeding assembly is arranged in the mounting cavity and is arranged close to the first sampling assembly, the cup feeding assembly is provided with a cup placing cavity, a conveying channel and a cup outlet, two ends of the conveying channel are respectively communicated with the cup placing cavity and the cup outlet, and the cup outlet is arranged corresponding to the rotating table;

the rotary driving part drives the rotary table to rotate, so that the detection station corresponds to the detection module, and the reaction station corresponds to the cup outlet.

6. The sample analyzer of claim 1, wherein the housing further comprises a replacing port communicating with the installation cavity, the replacing port corresponding to the separation module, and the separation module comprises:

the third frame body is arranged in the mounting cavity and corresponds to the replacing opening, and the third frame body is provided with a mounting groove;

the separation driving piece is arranged on one side, back to the mounting groove, of the third frame body, and an output shaft of the separation driving piece penetrates through the bottom wall of the mounting groove; and

the separation disc is movably arranged in the mounting groove and is detachably connected with the output shaft of the separation driving part, and the separation disc is provided with the separation cavity;

the separation driving part drives the separation disc to rotate so as to separate the sample to be detected in the separation cavity.

7. The sample analyzer as claimed in claim 6, wherein the third frame body comprises a mounting frame and a separating seat, the mounting frame is disposed in the mounting cavity and is disposed corresponding to the replacing port, the mounting frame is provided with a sliding rail, the separating seat is slidably connected with the sliding rail, the separating seat is provided with the mounting groove, and the separating driving member is disposed on a side of the separating seat opposite to the mounting groove;

the separation module is characterized in that the separation module further comprises a replacement driving piece, the replacement driving piece is arranged on the mounting frame and connected with the separation seat, and the replacement driving piece drives the separation seat to drive the separation disc to enter or exit the mounting cavity.

8. The sample analyzer of claim 6, wherein the housing is further provided with a movable baffle corresponding to the replacement port, and the movable baffle is movably connected with the housing to open or close the replacement port;

and/or the casing is also provided with a placing frame adjacent to the replacing port, and the placing frame is provided with a placing cavity for placing the separation disc;

and/or, the casing still is equipped with the intercommunication the waste material mouth of installation cavity, the waste material mouth with it sets up to change the mouth adjacent, and with the detection module corresponds, sample analyzer still includes the garbage collection box, garbage collection box detachably locates waste material mouth department is used for collecting detect the waste material after the module detects.

9. The sample analyzer as claimed in claim 2, wherein the sample to be tested is provided with an identification code, the sample analyzer further comprises a detection member, the detection member is disposed on the housing and corresponds to the sample feeding stage, and the detection member is used for detecting the identification code of the sample to be tested.

10. The sample analyzer of claim 9, wherein the sample entry station is configured with a puncture position and a sample aspirating position, the puncture position corresponding to the first sampling assembly configuration, and the sample aspirating position corresponding to the second sampling assembly configuration.

11. The sample analyzer of claim 10, wherein the sample stage is further provided with a circulating sample channel extending from the sample aspirating position to the puncturing position;

and/or the sampling platform is also provided with an emergency treatment position, and the emergency treatment position is arranged adjacent to the puncture position.

12. The sample analyzer of any of claims 1-11, further comprising a blending assembly, the blending assembly comprising:

the fixing frame is arranged in the mounting cavity and is adjacent to the sample inlet;

the blending driving piece is arranged on the fixing frame; and

the mixing clamping jaw is connected to the output shaft of the mixing driving part and provided with a clamping groove;

the blending driving part drives the blending clamping jaw to clamp a sample to be tested in the clamping groove so as to blend.

13. The sample analyzer of any of claims 1-11, further comprising a controller and a display screen disposed in the housing, the display screen disposed adjacent to the sample inlet, the controller electrically coupled to the display screen, the separation module, the detection module, and the transfer module.

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