CN112051406B

CN112051406B - Chemiluminescent immunoassay device

Info

Publication number: CN112051406B
Application number: CN202010696802.6A
Authority: CN
Inventors: 马杰; 陈有顺; 陆卓; 李雪; 陈林林; 谭福登
Original assignee: Shenzhen Rayto Life And Analytical Sciences Co ltd
Current assignee: Shenzhen Rayto Life And Analytical Sciences Co ltd
Priority date: 2020-07-20
Filing date: 2020-07-20
Publication date: 2024-03-29
Anticipated expiration: 2040-07-20
Also published as: CN112051406A

Abstract

The application belongs to the technical field of chemiluminescent immunoassay, and provides chemiluminescent immunoassay equipment which comprises a first rack, a sampling system, an incubation system and a cleaning system, wherein the sampling system, the incubation system and the cleaning system are arranged on the first rack; the incubation system comprises a mixing gripper assembly, a sample tray and an incubation tray, wherein a plurality of sample adding positions are arranged on the sample tray, a plurality of incubation positions are arranged in the incubation tray, and the mixing gripper assembly is used for carrying out mixing operation on a reaction cup at the sample adding positions and then transferring the reaction cup to the incubation positions; the cleaning system comprises a cleaning handle assembly, a substrate assembly, a first cleaning assembly and a second cleaning assembly, wherein the first cleaning assembly and the second cleaning assembly can clean and separate the reaction cup, the first cleaning assembly and the second cleaning assembly comprise a plurality of cleaning positions, and the cleaning handle assembly is used for transferring the reaction cup to the cleaning positions and transferring the reaction cup which is cleaned and separated on the first cleaning assembly to the sample adding position. Through the method and the device, the test of a plurality of test samples can be completed only by one-time starting, and the test speed is not reduced.

Description

Chemiluminescent immunoassay device

Technical Field

The application belongs to the technical field of chemiluminescent immunoassay, and more particularly relates to chemiluminescent immunoassay equipment.

Background

The chemiluminescence immunoassay has the advantages of high sensitivity, strong specificity, wide linear range, high automation degree and the like, and has become a main means of clinical diagnosis. Most of chemiluminescent immunoassay devices in the current market have low test speed, and particularly, the test speed of the whole machine can be reduced when sample reagents need to be cleaned in two steps.

Disclosure of Invention

An object of the embodiment of the application is to provide a material table to solve the technical problem that the test speed of chemiluminescent analysis equipment in the prior art is low.

In order to achieve the above purpose, the technical scheme adopted in one aspect of the application is as follows: the chemiluminescent immunoassay equipment comprises a first rack, a sampling system, an incubation system and a cleaning system, wherein the sampling system, the incubation system and the cleaning system are arranged on the first rack;

the incubation system comprises a mixing gripper assembly, a sample tray and an incubation tray, wherein a plurality of sample adding positions for placing reaction cups are arranged on the sample tray, the sampling system is used for injecting samples and/or reagents into the reaction cups positioned on the sample adding positions, a plurality of incubation positions are arranged in the incubation tray, and the mixing gripper assembly is used for carrying out mixing operation on the reaction cups injected with the samples and/or the reagents on the sample adding positions and then transferring the reaction cups to the incubation positions for incubation;

The cleaning system comprises a cleaning handle assembly, a substrate assembly and a first cleaning assembly and a second cleaning assembly, wherein the first cleaning assembly and the second cleaning assembly are arranged on the first rack and can be used for cleaning and separating reaction cups, the first cleaning assembly and the second cleaning assembly comprise a plurality of cleaning positions, the cleaning handle assembly is used for transferring the reaction cups located at the incubation positions to the cleaning positions and for transferring the reaction cups which are cleaned and separated on the first cleaning assembly to the sample loading positions, and the substrate assembly is used for filling substrates into the reaction cups which are cleaned and separated on the second cleaning assembly.

Optionally, the incubation system further includes a first base and a first cover plate, the first base and the first cover plate enclose to form a first installation cavity, and the sample tray and the incubation tray are coaxially and independently rotatably disposed in the first installation cavity; the first cover plate is provided with a transfer hole and a feeding hole, at least one sample adding position and at least one incubation position are correspondingly exposed in transfer, at least one sample adding position is correspondingly exposed in the feeding hole, the sampling system injects samples and/or reagents into the reaction cup through the feeding hole, the mixing gripper assembly is arranged on the first cover plate close to the transfer hole and is further used for transferring the reaction cup on the sample adding position exposed by the transfer hole to the incubation position exposed by the transfer hole after mixing operation.

Optionally, the cleaning system further comprises a cleaning disc, the cleaning handle assembly and the substrate assembly are arranged on the upper side of the cleaning disc, the first cleaning assembly and the second cleaning assembly comprise a plurality of cleaning pots which are arranged in an annular mode and are arranged in the cleaning disc, a mixing assembly which is arranged on the upper side of the cleaning disc and is used for uniformly mixing solid and liquid of the reaction cup on the cleaning position, a magnetic separation assembly which is arranged on the cleaning disc and is used for adsorbing and separating solid and liquid in the reaction cup, and a liquid suction and injection assembly which is arranged on the cleaning disc and is used for injecting liquid, sucking liquid and cleaning the reaction cup.

Optionally, the optical detection system further comprises an optical detection system arranged on the first rack, the optical detection system comprises a light measuring disc, a light measuring gripper assembly and a signal acquisition processing assembly, a cup placing position is arranged in the light measuring disc, the light measuring gripper assembly is used for transferring a reaction cup filled with a substrate to the cup placing position, and the signal acquisition processing assembly is used for acquiring and processing an optical signal sent by a sample in the reaction cup on the cup placing position.

Optionally, the first frame is further provided with a cup-dropping position, the optical detection system further comprises a waste liquid absorbing component arranged on the optical measuring disc, the optical measuring disc is provided with a waste liquid absorbing hole corresponding to the waste liquid absorbing component, a rotating part capable of rotating relative to the first frame is arranged in the optical measuring disc, the rotating part is provided with the cup-dropping position, and the rotating part sequentially drives the reaction cup to stop at a light measuring position corresponding to the signal collecting and processing component, a waste liquid absorbing liquid level corresponding to the waste liquid absorbing hole and the light measuring position, so that the signal collecting and processing component can collect optical signals sent by a sample in the reaction cup, the waste liquid absorbing component can absorb liquid in the reaction cup, and the light measuring gripper component can transfer the absorbed reaction cup to the cup-dropping position.

Optionally, the sampling system includes rotatable set up in sampling needle subassembly, reagent dish subassembly and reagent needle subassembly in the first frame, be provided with the sampling position in the first frame, the sampling needle subassembly set up in the sampling position with between the system of incubating, and be used for gathering sample on the sampling position and pour into in the reaction cup into, the reagent dish subassembly is close to the system of incubating sets up and has a plurality of coaxial ring reagent pipe positions that set up that supply the reagent pipe to place, the reagent needle subassembly set up in between the system of incubating with the reagent dish subassembly and be used for gathering reagent in the reagent pipe and pour into in the reaction cup into.

Optionally, still including set up in advance cup subassembly and rotatory handle subassembly in the first frame, advance the cup subassembly set up in keep away from of incubation system reagent dish subassembly one side, rotatory handle subassembly is located incubation system with advance between the cup subassembly, advance the cup subassembly including the cup position that advances that is loaded with the reaction cup, rotatory handle subassembly rotatable set up in the first frame and be used for with advance the reaction cup on the cup position and transfer to the application of sample position.

Optionally, the device further comprises a second rack connected with the first rack and a front end track system arranged on the first rack, wherein a sample rack placing area, a sample rack recycling area and a scheduling assembly are arranged on the second rack, the sample rack placing area is used for storing sample racks and is arranged on one side, far away from the incubation system, of the reagent tray assembly, and the sample rack recycling area is used for recycling the sample racks and is positioned between the reagent tray assembly and the sample rack placing area;

the front end track system comprises a sample feeding track assembly, a track changing assembly and a recovery track assembly, wherein the sample feeding track assembly is used for conveying a sample rack in a sample rack placing area to a sampling position, the track changing assembly is used for conveying the sample rack from the sample feeding track assembly to the recovery track assembly, the recovery track assembly is used for conveying the sample rack to a cup returning opening of a sample rack recovery area, and the dispatching assembly is arranged at the cup returning opening and used for conveying the sample rack from the recovery track assembly to the sample rack recovery area.

Optionally, the sample feeding track assembly includes a conventional track assembly and an emergency track assembly, an emergency insertion assembly is disposed on the second frame corresponding to the emergency track assembly, the first end of the conventional track assembly and the first end of the emergency track assembly are both provided with the sampling position, the second end of the conventional track assembly corresponds to a sample outlet of the sample rack placement area and is used for conveying the sample rack in the sample rack placement area to the corresponding sampling position, the second end of the emergency track assembly corresponds to the emergency insertion assembly and is used for conveying the sample rack on the emergency insertion assembly to the corresponding sampling position, and the track changing assembly can be selectively moved to the first end of the conventional track assembly, the first end of the emergency track assembly and the first end of the recovery track assembly.

Optionally, the device comprises a second rack and a plurality of first racks, wherein the first racks are sequentially connected, the second rack is connected to one sides of the racks, the front end track assemblies among the first racks correspond to each other, and the track transfer assemblies can be communicated with the sample injection track assemblies on two adjacent first racks and the recovery track assemblies on two adjacent first racks.

The beneficial effects of this application lie in:

compared with the prior art, the embodiment of the application enables the chemiluminescent immunoassay equipment to complete the test of a plurality of test samples only by starting up once through the plurality of sample adding positions and incubation positions, the sample is not required to be added in a stopping way, and the test speed of the whole machine is improved; meanwhile, the embodiment of the application comprises the first cleaning component and the second cleaning component, the cleaning handle component can transfer the reaction cup which is subjected to fourth-order cleaning separation on the first cleaning component to the sample adding position, the reaction cup is cleaned and separated through at least two sets of cleaning components, when sample reagents in the reaction cup need to be cleaned in two steps, the reaction cup can return to the sample adding position again after the cleaning and separation is finished to carry out next reagent adding, and the operation of next substrate filling of the reaction cup on the second cleaning component cannot be influenced, so that the test speed of the whole machine cannot be reduced.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are required for the embodiments or the description of the prior art will be briefly described below, it being obvious that the drawings in the following description are only some embodiments of the present application, and that other drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.

FIG. 1 is a schematic diagram of a first structure of a chemiluminescent immunoassay device according to an embodiment of the present application;

FIG. 2 is a schematic diagram of a second structure of a chemiluminescent immunoassay device according to an embodiment of the present application;

FIG. 3 is a schematic diagram of a third structure of a chemiluminescent immunoassay device according to an embodiment of the present application;

FIG. 4 is a top view of a chemiluminescent immunoassay device provided in an embodiment of the present application;

fig. 5 is a schematic structural diagram of an incubation system according to an embodiment of the present disclosure;

FIG. 6 is a schematic structural diagram of a cleaning system according to an embodiment of the present disclosure;

fig. 7 is a schematic structural diagram of a blending assembly according to an embodiment of the present disclosure;

fig. 8 is a schematic structural diagram of a liquid absorbing and injecting assembly according to an embodiment of the present disclosure;

fig. 9 is a schematic structural diagram of an optical detection system according to an embodiment of the present disclosure;

FIG. 10 is a schematic view of a portion of a cup feeding assembly according to an embodiment of the present disclosure;

FIG. 11 is a schematic view of a part of a chemiluminescent immunoassay device according to another embodiment of the present application;

FIG. 12 is a front view of a chemiluminescent immunoassay device according to another embodiment of the present application;

fig. 13 is a test flow chart of a chemiluminescent immunoassay device according to an embodiment of the present application.

Wherein, each reference sign in the figure:

chemiluminescent immunoassay device 10, first housing 100, cup-missing position 101, sampling system 120, sampling needle assembly 121, reagent tray assembly 122, reagent needle assembly 123, sampling position 124, incubation system 130, mixing gripper assembly 131, sample tray 132, incubation tray 133, sample-adding position 134, incubation position 135, transfer well 136, feed well 137, washing system 140, washing gripper assembly 141, substrate assembly 142, washing position 143, washing tray 144, mixing assembly 145, mixing section 1451, pipetting assembly 146, pipetting assembly 1461, optical detection system 150, photometric disc 151, photometric gripper assembly 152, signal acquisition processing assembly 153, waste-absorbing assembly 154, cup-feeding assembly 160, cup-feeding position 161, reaction cup bin 162, up-down transport assembly 163, chute 164, rotating motor 165, cup-feeding tray 166, rotating gripper assembly 167, sample-feeding track assembly 171 conventional track assembly 1711, emergency track assembly 1712, track-changing assembly 172, recycling track assembly 173, second housing 200, sample-holder placement area 210, sample-holder assembly 220, sample-deployment-area 230, emergency-deployment-unit-240, sample-handling assembly 500, and reaction-stage-control-device-500-receiving assembly.

Detailed Description

In order to make the technical problems, technical schemes and beneficial effects to be solved by the present application more clear, the present application is further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are for purposes of illustration only and are not intended to limit the present application.

It will be understood that when an element is referred to as being "mounted" or "disposed" on another element, it can be directly on the other element or be indirectly on the other element. When an element is referred to as being "connected to" another element, it can be directly connected to the other element or be indirectly connected to the other element.

It is to be understood that the terms "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," and the like indicate or are based on the orientation or positional relationship shown in the drawings, merely to facilitate description of the present application and simplify description, and do not indicate or imply that the devices or elements referred to must have a particular orientation, be configured and operated in a particular orientation, and therefore should not be construed as limiting the present application.

Furthermore, the terms "first," "second," and the like, are used for descriptive purposes only and are not to be construed as indicating or implying a relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defining "a first" or "a second" may explicitly or implicitly include one or more such feature. In the description of the present application, the meaning of "a plurality" is two or more, unless explicitly defined otherwise.

Referring to fig. 1 to 4, a chemiluminescent immunoassay device 10 according to an embodiment of the present application includes a first housing 100, a sampling system 120 disposed on the first housing 100, an incubation system 130, and a washing system 140;

the incubation system 130 comprises a mixing gripper assembly 131, a sample tray 132 and an incubation tray 133, wherein a plurality of sample adding positions 134 for placing the reaction cups 300 are arranged on the sample tray 132, the sampling system 120 is used for injecting samples and/or reagents into the reaction cups 300 positioned on the sample adding positions 134, a plurality of incubation positions 135 are arranged in the incubation tray 133, and the mixing gripper assembly 131 is used for transferring the reaction cups 300 injected with the samples and/or the reagents on the sample adding positions 134 to the incubation positions 135 for incubation after mixing operation;

the cleaning system 140 comprises a cleaning gripper assembly 141, a substrate assembly 142, and a first cleaning assembly and a second cleaning assembly which are arranged on the first frame 100 and can clean and separate the reaction cup 300, wherein the first cleaning assembly and the second cleaning assembly comprise a plurality of cleaning positions 143, the cleaning gripper assembly 141 is used for transferring the reaction cup 300 positioned at the incubation position 135 to the cleaning position 143 and transferring the reaction cup 300 cleaned and separated on the first cleaning assembly to the sample adding position 134, and the substrate assembly 142 is used for adding substrates into the reaction cup 300 cleaned and separated on the second cleaning assembly.

Wherein, when the sample reagent in the reaction cup 300 only needs to undergo one-step cleaning (commonly called "one-step method"), the cleaning grip transfers the reaction cup 300 from the incubation position 135 to the cleaning position 143 of the first cleaning assembly, and the substrate is injected into the substrate assembly 142 after cleaning by the first cleaning assembly; when the sample reagents in the cuvette 300 need to undergo two-step washing (commonly referred to as "two-step method"), the washing hand moves the cuvette 300 from the incubation site 135 to the washing site 143 of the second washing unit, and returns to the sample loading site 134 after washing by the second washing unit.

In this embodiment, the device can be started up at a time to test a plurality of test samples through the plurality of sample adding positions 134 and the incubation positions 135, so that the test speed of the whole machine is improved; the reaction cup 300 of the one-step method and the reaction cup 300 of the two-step method are respectively cleaned by different cleaning components, and the two cleaning components are not interfered with each other, so that the reaction cup 300 of the two-step method can not influence the subsequent procedures of the reaction cup 300 of the one-step method, and the testing speed of the whole machine can not be reduced.

It will be appreciated that the chemiluminescent immunoassay device 10 further comprises a control system 250 in control connection with the incubation system 130, the washing system 140. Control system 250 controls incubation system 130 and washing system 140 to do so.

In one embodiment, referring to fig. 5, the incubation system 130 further comprises a first base and a first cover plate that enclose a first mounting chamber, and the sample tray 132 and the incubation tray 133 are coaxially and independently rotatably disposed within the first mounting chamber; the first cover plate is provided with a transfer hole 136 and a feeding hole 137, the transfer hole 136 correspondingly exposes at least one sample adding position 134 and at least one incubation position 135, the feeding hole 137 correspondingly exposes at least one sample adding position 134, the sampling system 120 injects samples and/or reagents into the reaction cup 300 through the feeding hole 137, and the mixing gripper assembly 131 is arranged on the first cover plate close to the transfer hole 136 and is further used for uniformly mixing the reaction cup 300 on the sample adding position 134 exposed by the transfer hole 136 and then transferring the reaction cup 300 to the incubation position 135 exposed by the transfer hole 136.

The number of the charging holes 137 may be plural, and may be set according to actual requirements. In one embodiment, the number of addition holes 137 is three, with one addition hole 137 for adding a sample, one addition hole 137 for adding a first reagent, and one addition hole 137 for adding a second reagent.

Wherein the transfer well 136 is sized to simultaneously expose at least one loading site 134 and at least one incubation site 135. And when the mixing hand grip assembly 131 is uniformly mixed, at least one incubation site 135 exposed in the transfer hole 136 comprises an incubation site 135 where the cuvette 300 is not placed.

Wherein, after the mixing gripper assembly 131 goes deep into the transfer hole 136 to grasp the reaction cup 300 on the sample loading position 134 for mixing, the reaction cup 300 is directly sent to the incubation position 135 in the transfer hole 136.

It will be appreciated that incubation system 130 also includes a first drive mechanism that drives rotation of sample tray 132 and a second drive mechanism that drives rotation of incubation tray 133. The control system 250 is electrically connected to the first driving mechanism and the second driving mechanism, and controls the first driving mechanism and the second driving mechanism to operate to drive the sample tray 132 and the incubation tray 133 to rotate by a command angle, respectively. The first driving mechanism and the second driving mechanism can be motors or the combination of the motors and various transmission systems, and are not limited herein.

In a specific example, the sample tray 132 is located outside the incubation tray 133, the sample tray 132 includes a circle of sample adding sites 134, and the incubation tray 133 includes a plurality of circles of incubation sites 135, mainly considering that incubation of the reaction cups 300 at the incubation sites 135 needs to be performed for a period of time, that is, the reaction cups 300 at the incubation sites 135 have a fluidity smaller than that of the reaction cups 300 at the sample adding sites 134, so that the test speed is not reduced, and the number of incubation sites 135 is more than the sample grade.

Wherein the incubation system 130 may also include other structures, such as a temperature control assembly to control the incubation temperature, without limitation.

In this embodiment, the sample tray 132 and the incubation tray 133 are integrated into the first mounting chamber, which is advantageous for reducing the size of the apparatus; meanwhile, the mixing tongs are integrated on the first cover plate, the working face space of the equipment is further utilized, the size of the equipment is reduced, the miniaturization of the equipment is facilitated, meanwhile, the conveying time of the mixing tongs assembly 131 is shortened through the coaxial arrangement of the sample tray 132 and the incubation tray 133, and the testing process is accelerated.

The mixing gripper comprises a displacement driving mechanism, a displacement table connected with the displacement driving mechanism, a third driving mechanism and a gripper mechanism, wherein the third driving mechanism is connected with the gripper mechanism and drives the gripper mechanism to rotate, and the displacement driving mechanism drives the displacement table to move on a horizontal plane and a vertical plane. When the displacement driving mechanism drives the displacement table to move, the gripper mechanism and the third driving mechanism are driven to move to the position above the feeding position or the incubation position 135 exposed by the transfer hole 136, the gripper mechanism is switched between an open state and a closed state to grip the reaction cup 300, and the third driving mechanism is used for driving the gripper mechanism to rotate the reaction cup 300 so as to complete the mixing operation. The gripper mechanism can realize the drive that operating condition switched through mechanical transmission structure, for example, the gripper mechanism can include a plurality of grippers, and the one end of every gripper can be used for snatching reaction cup 300, and the other end is as the drive end, and the middle part then can articulate on a fixed part, and same driving piece can be connected to the other end of a plurality of grippers, and the driving piece moves along vertical direction, drives the one end of a plurality of grippers and rotates, realizes the switching between opening state and closure state of gripper mechanism.

Other existing modes can be adopted for the mixing grip, and the mixing grip is not limited in this regard.

In an alternative embodiment, referring to fig. 6, the cleaning system 140 further includes a cleaning disc 144, the cleaning gripper assembly 141 and the substrate assembly 142 are disposed on an upper side of the cleaning disc 144, the first cleaning assembly and the second cleaning assembly each include a cleaning pot having a plurality of cleaning sites 143 disposed in a ring shape and rotatably disposed on the cleaning disc 144, a mixing assembly 145 disposed on the upper side of the cleaning disc 144 for mixing solid and liquid of the reaction cup 300 on the cleaning sites 143, a magnetic separation assembly disposed on the cleaning disc 144 for adsorbing and separating solid and liquid in the reaction cup 300, and a liquid suction and injection assembly 146 disposed on the cleaning disc 144 for injecting, sucking and cleaning the reaction cup 300, and the cleaning pot of the first cleaning assembly and the cleaning pot of the second cleaning assembly can rotate independently.

The cleaning pot of the first cleaning component and the cleaning pot of the second cleaning component are coaxial and independently and rotatably arranged.

Illustratively, the cleaning tray 144 includes a second base and a second cover plate that enclose a second mounting chamber, in which a first cleaning pan and a second cleaning pan are coaxially disposed that are capable of independent rotation, and a plurality of cleaning stations 143 are disposed on the first cleaning pan and the second cleaning pan. The mixing component 145 and the liquid suction and injection component 146 are installed on the second cover plate, the magnetic separation component is installed in the second installation cavity, the magnetic separation component is installed corresponding to the first cleaning pot and the second cleaning pot respectively, and the magnetic bead separation component is configured corresponding to the mixing component 145 and the liquid suction and injection component 146.

In an embodiment, referring to fig. 6, 7 and 8, the cleaning system 140 is a fourth-order cleaning system 140, and includes a first mixing assembly, a first liquid-absorbing and injecting assembly, a second mixing assembly and a second liquid-absorbing and injecting assembly that are sequentially disposed, where the first mixing assembly and the second mixing assembly include two sets of mixing portions 1451, and each set of mixing portions 1451 corresponds to a first mixing portion of the first cleaning assembly and a second mixing portion of the second cleaning assembly; the first and second liquid-suction and liquid-injection assemblies each include two sets of liquid-suction and liquid-injection portions 1461, each set of liquid-suction and liquid-injection portions 1461 including a first liquid-suction and liquid-injection portion corresponding to the first cleaning assembly and a second liquid-suction and liquid-injection portion corresponding to the second cleaning assembly. The magnetic bead separation assembly includes magnetic separation portions corresponding to the mixing portion 1451 and the liquid suction and injection portion 1461, and the magnetic separation portions include a first magnetic separation portion corresponding to the first cleaning assembly and a second magnetic separation portion corresponding to the second cleaning assembly. Wherein, a mixing part 1451, a liquid sucking and injecting part 1461 and a magnetic separating part are a group of cleaning groups and complete a cleaning stage for the reaction cup 300. The process of one cleaning stage is liquid injection, uniform mixing, magnetic bead separation and waste liquid absorption; thus, four cleaning sets may achieve a four-stage cleaning of the cuvette 300.

Wherein, each mixing part 1451 comprises two mixing ends, one mixing end corresponds to the first cleaning pot, and the other mixing end corresponds to the second cleaning pot. Meanwhile, the liquid sucking and injecting part 1461 also comprises two needle tube ends, one needle tube end corresponds to the first cleaning pot, the other needle tube end corresponds to the second cleaning pot, and the needle tube end is provided with a needle tube for injecting liquid into the reaction cup and absorbing liquid in the reaction cup.

Further, the mixing assembly 145 and the liquid sucking and injecting assembly 146 are integrated on a mounting frame, and the specific structure can refer to the existing structure and is not described herein.

In this embodiment, the cleaning system can realize four-stage cleaning through the two mixing components 145 and the two liquid sucking and injecting components 146, and has the characteristic of compact structure.

In one embodiment, referring to fig. 1 to 4, and fig. 9, the chemiluminescent immunoassay device 10 further includes an optical detection system 150 disposed on the first rack 100, the optical detection system 150 includes a photometric disc 151, a photometric grip assembly 152, and a signal acquisition processing assembly 153, a cup placing position is disposed in the photometric disc 151, the photometric grip assembly 152 is used for transferring the reaction cup 300 filled with the substrate to the cup placing position, and the signal acquisition processing assembly 153 is used for acquiring and processing an optical signal emitted from a sample in the reaction cup 300 on the cup placing position.

Wherein the optical detection system 150 is located at one side of the cleaning system 140.

As can be appreciated, referring to fig. 1-4, the control system 250 includes a host computer in signal communication with the signal acquisition processing component 153, the host computer receiving and processing data transmitted by the signal acquisition processing component 153 and generating test results.

In a possible embodiment, referring to fig. 9, the first rack 100 is further provided with a cup-dropping position 101, the optical detection system 150 further includes a waste liquid sucking component 154 disposed on the optical measuring disc 151, a waste liquid sucking hole corresponding to the waste liquid sucking component 154 is disposed on the optical measuring disc 151, a rotating portion capable of rotating relative to the first rack 100 is disposed in the optical measuring disc 151, the rotating portion is provided with a cup-dropping position, and the rotating portion sequentially drives the reaction cup 300 to rest on a light measuring position corresponding to the signal collecting and processing component 153, a waste liquid sucking level corresponding to the waste liquid sucking hole, and a light measuring position when the signal collecting and processing component 153 collects an optical signal sent by a sample in the reaction cup 300, the waste liquid sucking component 154 sucks liquid in the reaction cup 300, and the light measuring gripper component 152 transfers the sucked reaction cup 300 to the cup-dropping position 101.

In a specific example, the optical measuring disc 151 includes a third base and a third cover, where the third base and the third cover enclose to form a third installation cavity, the rotating portion is disposed in the third cavity, and the lighting end of the signal collecting and processing component 153 is disposed in the third cavity. The waste liquid absorbing component 154 is located on the third cover plate, the photometry position is a photometry hole site arranged on the third cover plate, the photometry hole site is close to the photometry gripper component 152, and the photometry gripper component 152 is placed on the cup placing position through the photometry hole site after grabbing the reaction cup 300. The waste liquid sucking level is a waste liquid sucking hole position arranged on the third cover plate, and the waste liquid sucking component 154 sucks the liquid in the reaction cup 300 in the third chamber by penetrating through the waste liquid sucking hole position.

Wherein, snatch reaction cup 300 and send to putting the cup position through photometry tongs subassembly 152, signal acquisition and processing assembly carry out photometry to the reaction cup 300 of preventing on the cup position can be realized through prior art, and is not described in detail here. The waste liquid sucking assembly 154 can also be implemented by the prior art, and is not described herein.

Further, referring to fig. 4, under the first frame 100, a waste cup bin for collecting the waste reaction cups 300 is provided corresponding to the cup-missing position 101.

In another embodiment, referring to fig. 2 and 4, the sampling system 120 includes a sampling needle assembly 121 rotatably disposed on the first housing 100, a reagent tray assembly 122 and a reagent needle assembly 123, the sampling site 124 is disposed on the first housing 100, the sampling needle assembly 121 is disposed between the sampling site 124 and the incubation system 130 and is used to collect a sample on the sampling site 124 and inject it into the reaction cup 300, the reagent tray assembly 122 is disposed near the incubation system 130 and has a plurality of coaxially disposed annular reagent tube sites for placement of reagent tubes, and the reagent needle assembly 123 is disposed between the incubation system 130 and the reagent tray assembly 122 and is used to collect reagents in the reagent tubes and inject them into the reaction cup 300.

Wherein, each annular reagent tube position includes a plurality of reagent tube positions and a plurality of reagent tube positions are annular setting. The test of a plurality of sample reagents can be completed simultaneously by arranging a plurality of reagent tube positions on the reagent disk, the test is not required to be interrupted due to the fact that the reagents are used up, and the test speed is reduced.

In a possible embodiment, the number of reagent needle assemblies 123 may be plural, the number of sample adding sites 134 is plural, and each reagent needle assembly 123 adds reagent to the reaction cup 300 on one sample adding site 134 correspondingly, so as to meet the requirement of adding various reagents, and speed up the test.

In one embodiment, the reagent needle assembly 123 rests in a first fixed position corresponding to the sample application station 134 and a second fixed position corresponding to a reagent tube station. Correspondingly, the reagent disk assembly 122 includes at least one turntable, and when a plurality of turntables exist, the turntables are coaxial and independently rotated, one turntable corresponds to one reagent needle assembly 123, an annular reagent tube position is arranged on the turntable, and the reagent tube on the turntable is driven to move to a second fixed position corresponding to the reagent needle assembly 123 when the turntable rotates.

In a possible embodiment, the reagent disk assembly 122 includes a fourth base and a fourth cover plate, the turntable is rotatably disposed in the fourth base, the fourth cover plate covers the fourth base, and a fifth driving mechanism for driving the turntable to rotate is disposed under the fourth base. In other embodiments, the reagent disk assembly 122 may also include other structures, which are not described in detail herein.

In a possible embodiment, the reagent needle assembly 123 and the sampling needle assembly 121 each include a rotating base, a lifting assembly and a needle tube assembly, the rotating base is rotatably disposed on the first frame 100, the lifting assembly is disposed on the rotating base, the needle tube is disposed on the lifting assembly, the rotating base drives the needle tube assembly to rotate, and the lifting assembly drives the needle tube assembly to move up and down so that the needle tube assembly can be inserted into the tube to absorb liquid or the tube to be inserted into the liquid. Referring to existing solutions, in other embodiments, the reagent disk assembly 122 and the sampling needle assembly 121 may also include other structures, which are not described in detail herein.

In another embodiment, referring to fig. 2, 3 and 4, the chemiluminescent immunoassay device 10 further comprises a cup feeding assembly 160 and a rotary gripper assembly 167 disposed on the first frame 100, the cup feeding assembly 160 being disposed on a side of the incubation system 130 remote from the reagent tray assembly 122, the rotary gripper assembly 167 being disposed between the incubation system 130 and the cup feeding assembly 160, the cup feeding assembly 160 comprising a cup feeding position 161 loaded with a reaction cup 300, the rotary gripper assembly 167 being rotatably disposed on the first frame 100 and being configured to transfer the reaction cup 300 on the cup feeding position 161 to the loading position 134. The layout ensures that the device has compact structure and is beneficial to accelerating the test speed.

Referring to fig. 10, the cup feeding assembly 160 includes a reaction cup bin 162, an up-down conveying assembly 163, a chute 164 and a cup feeding disc 166, the reaction cup bin 162 is disposed on the first frame 100, the up-down conveying assembly 163 is disposed on the reaction cup bin 162 and is used for conveying a reaction cup 300 at the bottom of the reaction cup bin 162 to an upper outlet of the reaction cup bin 162, a first end of the chute 164 is disposed at the outlet, the other end of the chute 164 is correspondingly provided with the cup feeding disc 166, the cup feeding disc 166 is provided with a cup feeding position 161, and the chute 164 is used for sliding the reaction cup 300 at the outlet to the cup feeding position 161 along the chute 164. Wherein, the bottom of the reaction cup bin 162 stores the reaction cup 300, the outlet of the reaction cup bin 162 is higher than the cup inlet position 161, and the reaction cup 300 slides to the cup inlet position 161 along the chute 164 after reaching the outlet.

Further, the cup feeding assembly 160 further comprises a rotating motor 165, a plurality of cup feeding positions 161 arranged along a circular array are arranged on the cup feeding disc 166, and the rotating motor 165 drives the cup feeding disc 166 to rotate and can hover to a preset position. When the cup feeding disc 166 rotates and hovers to a preset position, the last cup feeding position 161 corresponds to the other end of the chute 164 to receive the reaction cup 300 sliding from the chute 164.

It is understood that the up-down conveying assembly 163 may include a motor and a lifting table driven by the motor through a driving belt, and the lifting table carries the reaction cup, or refer to other structures, so long as the reaction cup 300 can be transported from the lower portion of the reaction cup bin 162 to the upper portion of the reaction cup bin 162, which is not described herein.

In a possible embodiment, referring to fig. 2 and 4, the chemiluminescent immunoassay device 10 further comprises a second rack 200 connected to the first rack 100, and a front end rail system disposed on the first rack 100, wherein a sample rack placement area 210, a sample rack recovery area 220 and a dispatch assembly 230 are disposed on the second rack 200, the sample rack placement area 210 is used for storing the sample racks 400 and is disposed on a side of the reagent tray assembly 122 away from the incubation system 130, and the sample rack recovery area 220 is used for recovering the sample racks 400 and is located between the reagent tray assembly 122 and the sample rack placement area 210;

the front end rail system includes a sample introduction rail assembly 171, a track change assembly 172, and a recovery rail assembly 173, the sample introduction rail assembly 171 is used for transporting the sample rack 400 in the sample rack placing area 210 to the sampling position 124, the track change assembly 172 is used for transporting the sample rack 400 from the sample introduction rail assembly 171 to the recovery rail assembly 173, the recovery rail assembly 173 is used for transporting the sample rack 400 to a cup return opening of the sample rack recovery area 220, and the dispatch assembly 230 is arranged at the cup return opening and is used for transferring the sample rack 400 from the recovery rail assembly 173 to the sample rack recovery area 220.

The sample rack 400 on the sample feeding rail assembly 171 and the recovery rail assembly 173 can be transported by adopting a belt conveying mode, a chain wheel conveying mode and the like, and the sample feeding rail assembly and the recovery rail assembly are not particularly limited herein.

Wherein a plurality of sample tubes may be stored on the sample rack 400.

The embodiment can support automatic loading and unloading, and the sample quantity is stored greatly, so that the whole test speed and the throughput of the equipment are improved.

In one example, the track change assembly 172 includes a track change, a sixth drive mechanism that drives the track change in a first direction parallel to the transport direction of the feed track assembly and the recovery track assembly 173, and a seventh drive mechanism that drives the track change in a second direction directed from the first end of the feed track assembly to the first end of the recovery track assembly 173 to transfer the sample rack 400 from the feed track assembly to the recovery track assembly 173. The sixth driving mechanism may be a belt conveying mechanism, and the seventh driving mechanism may be a linear motor.

It will be appreciated that the track change assembly 172 may also include other structures, not limited herein.

As an example, the dispatch assembly 230 includes a dispatch robot that grips the sample racks 400 and transports the sample racks 400 to a designated location, and in other embodiments, the dispatch assembly 230 may include other structures, not limited herein.

By this embodiment, the chemiluminescent immunoassay device can automatically enter the sample rack 400 and automatically recover the sample rack 400. Both the sample rack placement area 210 and the sample rack recovery area 220 can place multiple sample racks 400, facilitating simultaneous testing of multiple samples.

In an embodiment, referring to fig. 2 and 4, the sample injection track assembly 171 includes a conventional track assembly 1711 and an emergency track assembly 1712, the emergency track assembly 1712 is disposed on the second rack 200, the first end of the conventional track assembly 1711 and the first end of the emergency track assembly 1712 are each disposed with a sample site 124, the second end of the conventional track assembly 1711 corresponds to the sample outlet of the sample rack placement area 210 for transporting the sample rack 400 in the sample rack placement area 210 to the first sample site, and the second end of the emergency track assembly 1712 corresponds to the emergency track assembly 240 for transporting the sample rack 400 on the emergency insert assembly 240 to the second sample site, and the track changing assembly 172 is selectively movable to the first end of the conventional track assembly 1711, the first end of the emergency track assembly 1712, and the first end of the recovery track assembly 173.

In the present embodiment, two sample rack 400 conveying rails are provided, which can satisfy the conventional test and emergency test.

The emergency rail assembly 1712 and the conventional rail assembly 1711 may be used to transport the sample rack 400 thereon by means of belt conveying, sprocket conveying, etc., which are not particularly limited herein.

Illustratively, the emergency insertion unit 240 includes a slide rail disposed on the second rack 200 and a slot slidably disposed on the slide rail, the slot being configured to receive the sample rack 400 requiring an emergency test, and the slot being extractable and insertable along the slide rail. When the presence of a sample rack 400 in the slot is detected, the dispatch robot carries the sample rack 400 onto the emergency track assembly 1712. In other embodiments, the emergency insertion module 240 may also include other structures, which are not described in detail herein.

Further, referring to fig. 2, 3 and 4, a scanning device 260 is disposed at the sample outlet of the sample rack placement area 210, the scanning device 260 is connected to the control system 250, and the scanning device 260 is used for scanning the information of the sample tube on the sample rack 400, so that the control system 250 stores the test result of the sample tube corresponding to the information of the sample tube. For example, after the sample rack 400 is grasped by the manipulator, the sample tubes on the sample rack 400 sequentially pass through the scanning device 260 in a certain direction, so that the information of each sample tube on the sample tubes is acquired by the scanning device 260. Likewise, sample tube information on the sample rack 400 on the emergency insertion module 240 may be scanned.

The arrangement of the scanning device 260 is beneficial to realizing the automatic matching of the test result and the test sample, and improves the intelligence of the equipment.

In an embodiment, referring to fig. 11 and 12, the chemiluminescent immunoassay device 10 includes a second rack 200 and a plurality of first racks 100, the plurality of first racks 100 are sequentially connected, and the second rack 200 is connected to one side of the plurality of racks, the front end rail assemblies among the plurality of first racks 100 correspond to each other, and the rail assembly 172 may be connected to the sample injection rail assemblies 171 on two adjacent first racks 100 and to the recovery rail assemblies 173 on two adjacent first racks 100.

Through the embodiment, the online connection of a plurality of first racks 100 can be realized, the testing quantity of the whole equipment is increased by multiple stages, and the testing speed is further increased.

For example, referring to fig. 11, the first racks 100 are connected by a stage connection block 500. One end of the stage connection block 500 is fastened and connected to one of the two adjacent first frames 100, and the other end is fastened and connected to the other of the two adjacent first frames 100, so that unsmooth connection between the first frames 100 is prevented.

Referring to fig. 2, 4 and 13, a test procedure of the chemiluminescent immunoassay device according to an embodiment of the present application is as follows: starting the analyzer, starting the whole analysis process by the computer, conveying the reaction cup 300 to the cup feeding position 161 at d by the cup feeding assembly 160, placing the reaction cup 300 to the sample feeding position at e from the cup feeding position 161 at d along the preset motion track by the rotary gripper assembly 167, conveying the reaction cup 300 to the sample feeding position 134 at f and/or the sample feeding position 134 at g by the sample tray 132, sucking the reagent from the reagent tray by the reagent needle assembly 123, injecting the reagent into the reaction cup 300, conveying the sample to the sample feeding position 134 at c by the sample tray 132, sucking the sample by the sampling needle assembly 121 from the sample feeding position, conveying the sample to the sample feeding position 134 at c along the preset motion track, injecting the sample into the reaction cup 300 by the rotary gripper assembly 132, conveying the reaction cup 300 to the sample feeding position 134 at m by the rotary gripper assembly 131, grabbing the reaction cup 300, uniformly mixing the sample at the incubation position 135 at m by the mixing gripper assembly 131, and after incubating the incubation time, conveying the reaction cup 300 to h by the incubation tray 133, conveying the sample to the washing gripper assembly 141 along the preset motion track, and grabbing the sample at i by the washing gripper assembly 144.

When the sample reagent in the reaction cup only needs one step of cleaning, the cleaning position 143 corresponding to the first cleaning component at i is not used, when the sample reagent in the reaction cup needs two steps of cleaning, the cleaning handle component 141 grabs and conveys the reaction cup 300 to the cleaning position 143 corresponding to the second cleaning component at i of the cleaning disc 144 along a preset motion track, and when the cleaning disc 144 rotates, the reaction cup 300 passes through the mixing component 145 and the liquid sucking and injecting component 146 are mixed and cleaned;

on the one hand, when the cleaning disc 144 rotates, the reaction cup 300 of the first cleaning assembly is driven to move below the bottom object assembly 142 to mix the substrates uniformly, after mixing, the cleaning pot 24 rotates to convey the reaction cup 300 to the j position, the photometric gripper assembly 152 grabs the reaction cup 300 along a preset movement track and conveys the reaction cup 300 to the k position of the photometric disc 151 to perform photometry, after photometry, the photometric disc 151 conveys the reaction cup 300 to the position l below the waste liquid absorbing assembly, after the waste liquid absorbing assembly 154 absorbs the liquid in the reaction cup 300, the photometric disc 151 conveys the reaction cup 300 back to the k position, and the photometric gripper assembly 151 grabs and conveys the reaction cup 300 to the cup dropping position 101 to be dropped into the waste cup bin. And displaying the test result by the computer, and ending the whole test flow.

On the other hand, when the cleaning disc 144 rotates, the reaction cup 300 of the first cleaning assembly is driven to move back to the position i, the cleaning handle assembly 141 grabs and conveys the reaction cup 300 from the cleaning position corresponding to the second cleaning assembly at the position i to the sample loading position 134 at the position h along the preset movement track, the sample disc 132 rotates to convey the reaction cup 300 to the sample loading position 134 at the position f and/or the sample loading position 134 at the position g, and the subsequent steps are executed.

The foregoing description of the preferred embodiments of the present application is not intended to be limiting, but is intended to cover any and all modifications, equivalents, and alternatives falling within the spirit and principles of the present application.

Claims

1. A chemiluminescent immunoassay device comprising a first housing (100), a sampling system (120) disposed on the first housing (100), an incubation system (130), and a washing system (140);

the incubation system (130) comprises a mixing gripper assembly (131), a sample tray (132) and an incubation tray (133), wherein a plurality of sample adding positions (134) for placing reaction cups (300) are arranged on the sample tray (132), the sampling system (120) is used for injecting samples and/or reagents into the reaction cups (300) arranged on the sample adding positions (134), a plurality of incubation positions (135) are arranged in the incubation tray (133), and the mixing gripper assembly (131) is used for transferring the reaction cups (300) with the samples and/or reagents injected on the sample adding positions (134) to the incubation positions (135) for incubation after mixing operation;

the cleaning system (140) comprises a cleaning handle assembly (141), a substrate assembly (142) and a first cleaning assembly and a second cleaning assembly which are arranged on the first rack (100) and can be used for cleaning and separating the reaction cup (300), wherein the first cleaning assembly and the second cleaning assembly respectively comprise a plurality of cleaning positions (143), the cleaning handle assembly (141) is used for transferring the reaction cup (300) positioned at the incubation position (135) to the cleaning positions (143) and transferring the reaction cup (300) which is cleaned and separated on the first cleaning assembly to the sample adding position (134), and the substrate assembly (142) is used for adding substrates into the reaction cup (300) which is cleaned and separated on the second cleaning assembly;

The incubation system (130) further comprises a first base and a first cover plate, wherein the first base and the first cover plate enclose to form a first installation cavity, and the sample tray (132) and the incubation tray (133) are coaxially and independently arranged in the first installation cavity in a rotating manner; the first cover plate is provided with a transfer hole (136) and a feeding hole (137), the transfer hole (136) is correspondingly exposed to at least one sample adding position (134) and at least one incubation position (135), the feeding hole (137) is correspondingly exposed to at least one sample adding position (134), the sampling system (120) injects samples and/or reagents into the reaction cup (300) through the feeding hole (137), and the mixing gripper assembly (131) is arranged on the first cover plate close to the transfer hole (136) and is further used for uniformly mixing the reaction cup (300) on the sample adding position (134) exposed by the transfer hole (136) and then transferring the mixture to the incubation position (135) exposed by the transfer hole (136); wherein the number of the charging holes (137) is a plurality.

2. The apparatus of claim 1, wherein the cleaning system (140) further comprises a cleaning tray (144), the cleaning handle assembly (141) and the substrate assembly (142) are disposed on the upper side of the cleaning tray (144), and the first cleaning assembly and the second cleaning assembly each comprise a cleaning pot rotatably disposed in the cleaning tray (144) and having a plurality of cleaning positions (143) disposed in a ring shape, a mixing assembly disposed on the upper side of the cleaning tray (144) and used for uniformly mixing solid and liquid in a reaction cup (300) disposed on the cleaning positions (143), a magnetic separation assembly disposed on the cleaning tray (144) and used for adsorbing and separating solid and liquid in the reaction cup (300), and a liquid injection assembly disposed on the cleaning tray (144) and used for injecting, sucking and cleaning the reaction cup (300).

3. The chemiluminescent immunoassay device of claim 1 or 2 further comprising an optical detection system (150) disposed on the first housing (100), the optical detection system (150) comprising a photometric disc (151), a photometric grip assembly (152) and a signal acquisition processing assembly (153), a cup placement site being disposed in the photometric disc (151), the photometric grip assembly (152) being configured to transfer a reaction cup (300) filled with a substrate to the cup placement site, the signal acquisition processing assembly (153) being configured to acquire and process an optical signal emitted by a sample within the reaction cup (300) disposed on the cup placement site.

4. A device as claimed in claim 3, wherein the first frame (100) is further provided with a cup-dropping position (101), the optical detection system (150) further comprises a waste liquid sucking component (154) disposed on the optical disc (151), a waste liquid sucking hole is disposed on the optical disc (151) corresponding to the waste liquid sucking component (154), a rotating part capable of rotating relative to the first frame (100) is disposed in the optical disc (151), the cup-dropping position is disposed on the rotating part, and the rotating part sequentially drives the reaction cup (300) to rest on a light measuring position corresponding to the signal collecting and processing component (153), a waste liquid sucking level corresponding to the waste liquid sucking hole and the light measuring position, so that the optical signal sent by the sample in the reaction cup (300) is collected by the signal collecting and processing component (153), the liquid in the reaction cup (300) is sucked by the waste liquid sucking component (154), and the reaction cup (300) is transferred to the cup-dropping position (101) by the light measuring hand component (152).

5. The device according to claim 1 or 2, wherein the sampling system (120) comprises a sampling needle assembly (121), a reagent disc assembly (122) and a reagent needle assembly (123) rotatably arranged on the first frame (100), a sampling site (124) is arranged on the first frame (100), the sampling needle assembly (121) is arranged between the sampling site (124) and the incubation system (130) and is used for collecting a sample on the sampling site (124) and injecting the sample into the reaction cup (300), the reagent disc assembly (122) is arranged close to the incubation system (130) and is provided with a plurality of coaxially arranged annular reagent tube positions for placing reagent tubes, and the reagent needle assembly (123) is arranged between the incubation system (130) and the reagent disc assembly (122) and is used for collecting reagents in the reagent tubes and injecting the reagents into the reaction cup (300).

6. The apparatus of claim 5, further comprising a cup feeding assembly (160) and a rotary gripper assembly (167) disposed on the first frame (100), the cup feeding assembly (160) disposed on a side of the incubation system (130) remote from the reagent tray assembly (122), the rotary gripper assembly (167) disposed between the incubation system (130) and the cup feeding assembly (160), the cup feeding assembly (160) including a cup feeding position (161) loaded with reaction cups (300), the rotary gripper assembly (167) being rotatably disposed on the first frame (100) and configured to transfer the reaction cups (300) on the cup feeding position (161) to the loading position (134).

7. The apparatus of claim 6, further comprising a second rack (200) coupled to the first rack (100) and a front end rail system disposed on the first rack (100), the second rack (200) having a sample rack placement area (210), a sample rack recovery area (220), and a scheduling assembly (230), the sample rack placement area (210) for storing sample racks (400) and disposed on a side of the reagent tray assembly (122) remote from the incubation system (130), the sample rack recovery area (220) for recovering the sample racks (400) and located between the reagent tray assembly (122) and the sample rack placement area (210);

the front end track system comprises a sample feeding track assembly (171), a track changing assembly (172) and a recovery track assembly (173), wherein the sample feeding track assembly (171) is used for conveying a sample rack (400) in a sample rack placing area (210) to a sampling position (124), the track changing assembly (172) is used for conveying the sample rack (400) from the sample feeding track assembly (171) to the recovery track assembly (173), the recovery track assembly (173) is used for conveying the sample rack (400) to a cup return opening of a sample rack recovery area (220), and the scheduling assembly (230) is arranged at the cup return opening and used for transferring the sample rack (400) from the recovery track assembly (173) to the sample rack recovery area (220).

8. The apparatus of claim 7, wherein the sample introduction track assembly (171) comprises a conventional track assembly (1711) and an emergency track assembly (1712), the second housing (200) being provided with an emergency insertion assembly (240) corresponding to the emergency track assembly (1712), the conventional track assembly (1711) first end and the emergency track assembly (1712) first end each being provided with the sampling site (124), the second end of the conventional track assembly (1711) corresponding to the sample exit of the sample rack placement area (210) for transporting the sample rack (400) within the sample rack placement area (210) to the corresponding sampling site (124), the second end of the emergency track assembly (1712) corresponding to the emergency insertion assembly (240) being provided for transporting the sample rack (400) on the emergency insertion assembly (240) to the corresponding sampling site (124), the transfer track assembly (172) being selectively movable to the first end of the conventional track assembly (173) and the first end of the emergency track assembly (1712).

9. The apparatus of claim 7, comprising a second rack (200) and a plurality of said first racks (100), a plurality of said first racks (100) being connected in sequence, and said second rack (200) being connected to one side of a plurality of said racks, said front end rail assemblies between a plurality of said first racks (100) corresponding, said track transfer assembly (172) being communicable with said sample introduction rail assemblies (171) on adjacent two of said first racks (100) and with said recovery rail assemblies (173) on adjacent two of said first racks (100).