CN111296463A - Compound pesticide containing trifluoro-benzene pyrimidine and chlorfenapyr - Google Patents
Compound pesticide containing trifluoro-benzene pyrimidine and chlorfenapyr Download PDFInfo
- Publication number
- CN111296463A CN111296463A CN202010187233.2A CN202010187233A CN111296463A CN 111296463 A CN111296463 A CN 111296463A CN 202010187233 A CN202010187233 A CN 202010187233A CN 111296463 A CN111296463 A CN 111296463A
- Authority
- CN
- China
- Prior art keywords
- chlorfenapyr
- pesticide
- trifluoro
- compound
- carrier
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- CWFOCCVIPCEQCK-UHFFFAOYSA-N chlorfenapyr Chemical compound BrC1=C(C(F)(F)F)N(COCC)C(C=2C=CC(Cl)=CC=2)=C1C#N CWFOCCVIPCEQCK-UHFFFAOYSA-N 0.000 title claims abstract description 68
- 239000000575 pesticide Substances 0.000 title claims abstract description 43
- JWXJRRHHNXLANU-UHFFFAOYSA-N pyrimidine 1,2,3-trifluorobenzene Chemical compound N1=CN=CC=C1.FC=1C(=C(C=CC1)F)F JWXJRRHHNXLANU-UHFFFAOYSA-N 0.000 title claims abstract description 38
- 150000001875 compounds Chemical class 0.000 title claims abstract description 31
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- LYBDHGMSPQBSNW-UHFFFAOYSA-N 2,4,5-trifluoropyrimidine Chemical compound FC1=NC=C(F)C(F)=N1 LYBDHGMSPQBSNW-UHFFFAOYSA-N 0.000 claims description 17
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- 239000008273 gelatin Substances 0.000 description 1
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- 238000000227 grinding Methods 0.000 description 1
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- YWTYJOPNNQFBPC-UHFFFAOYSA-N imidacloprid Chemical compound [O-][N+](=O)\N=C1/NCCN1CC1=CC=C(Cl)N=C1 YWTYJOPNNQFBPC-UHFFFAOYSA-N 0.000 description 1
- 229940056881 imidacloprid Drugs 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000010902 jet-milling Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 229940031703 low substituted hydroxypropyl cellulose Drugs 0.000 description 1
- 231100000053 low toxicity Toxicity 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 235000010446 mineral oil Nutrition 0.000 description 1
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- 235000019426 modified starch Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- SNQQPOLDUKLAAF-UHFFFAOYSA-N nonylphenol Chemical compound CCCCCCCCCC1=CC=CC=C1O SNQQPOLDUKLAAF-UHFFFAOYSA-N 0.000 description 1
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- 230000000607 poisoning effect Effects 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920005646 polycarboxylate Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- FKQANDIAURBSIM-UHFFFAOYSA-N pyrimidine 1,2,3-trichlorobenzene Chemical compound N1=CN=CC=C1.ClC=1C(=C(C=CC1)Cl)Cl FKQANDIAURBSIM-UHFFFAOYSA-N 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000012865 response to insecticide Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- PYODKQIVQIVELM-UHFFFAOYSA-M sodium;2,3-bis(2-methylpropyl)naphthalene-1-sulfonate Chemical compound [Na+].C1=CC=C2C(S([O-])(=O)=O)=C(CC(C)C)C(CC(C)C)=CC2=C1 PYODKQIVQIVELM-UHFFFAOYSA-M 0.000 description 1
- 239000001587 sorbitan monostearate Substances 0.000 description 1
- 235000011076 sorbitan monostearate Nutrition 0.000 description 1
- 229940035048 sorbitan monostearate Drugs 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000001384 succinic acid Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 230000005062 synaptic transmission Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000002723 toxicity assay Methods 0.000 description 1
- XZZNDPSIHUTMOC-UHFFFAOYSA-N triphenyl phosphate Chemical compound C=1C=CC=CC=1OP(OC=1C=CC=CC=1)(=O)OC1=CC=CC=C1 XZZNDPSIHUTMOC-UHFFFAOYSA-N 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
Landscapes
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Agronomy & Crop Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Toxicology (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention belongs to the field of pesticide, and particularly relates to a compound pesticide containing trifluorophenylpyrimidine and chlorfenapyr, wherein the weight ratio of the trifluorophenylpyrimidine to the chlorfenapyr is 10: 1-1: 10, and the preferable ratio is 3: 1-1: 3. The composite pesticide also comprises a functional auxiliary agent and a carrier, and can be prepared into a suspending agent, a wettable powder, a water dispersible granule, an aqueous emulsion and a microemulsion, wherein the active ingredient consisting of the trifluorobenzene pyrimidine and the chlorfenapyr accounts for 5-80% of the total weight. The invention is used for preventing and controlling pests in paddy fields, and has excellent prevention and control effects on rice planthoppers and rice leaf rollers; the two have no interaction resistance, and can be used for controlling resistant pests; the synergistic effect is obvious, and the obvious synergistic effect is achieved instead of simple superposition of the activities of all components; the field dosage of the active ingredients is reduced, the production and use cost is reduced, the pesticide residue and the environmental pollution are reduced, and the generation of the resistance of the paddy field is overcome and the generation speed of the drug resistance of the nematodes is delayed.
Description
Technical Field
The invention belongs to the field of agricultural insecticides, and particularly relates to a compound insecticide containing trifluorophenylpyrimidine and chlorfenapyr and a preparation method thereof.
Background
Trifluoropyrimidine is the only inhibitory agent in the existing pesticides acting on nicotinic acetylcholine receptors, namely, the nicotinic acetylcholine receptor inhibitor. Like nicotinic acetylcholine receptor competitive modulators such as imidacloprid, trifluorobenzene pyrimidine blocks neurotransmission by the target pest by binding to the positive site of the nicotinic acetylcholine receptor to exert pesticidal activity. Due to the different binding patterns of competitive modulators to nicotinic acetylcholine receptors and their competitive relationship, trifluorfluoropyrimidine is able to effectively control pests such as rice planthopper that develop resistance to neonicotinoid insecticides, which international committee on insecticide resistance action has assigned to subgroup 4E.
The chlorfenapyr is a novel pyrrole compound, acts on mitochondria of cells in an insect body, acts through a multifunctional oxidase in the insect body, and mainly inhibits the conversion of Adenosine Diphosphate (ADP) to Adenosine Triphosphate (ATP). Adenosine triphosphate stores cells and provides the energy necessary to sustain their vital functions. The pesticide has strong permeability on leaf surface, has a certain systemic effect, has the characteristics of wide insecticidal spectrum, high control effect, long lasting effect and safety, and can control resistant pests. Has excellent control effect on boring, sucking and chewing pests and mites, is more effective than cypermethrin and cyfluthrin, and has stronger acaricidal activity than dicofol and cyhexatin. The medicament has the following characteristics: broad-spectrum insecticidal and acaricidal agents; has stomach toxicity and contact poisoning effects; no cross resistance with other insecticides; moderate residual activity on crops; absorbing the active ingredients in nutrient solution through root system; the oral toxicity to mammals is moderate, and the transdermal toxicity is low; the effective application amount is low, and the remarkable insecticidal and acaricidal activity and the unique chemical structure of the pesticide composition are widely regarded and paid attention to by people.
At present, the production and use costs of the trifluoropyrimidine and the chlorfenapyr are high, the damage to the ecological environment is large, the safety to crops is low, and the trifluoropyrimidine and the chlorfenapyr have great resistance risks after being used alone for a long time. The compounding of different kinds of components is the most common method for controlling resistant pests. The different components are compounded, so that the control effect can be improved, the insecticidal range can be enlarged, the using amount of the effective components can be reduced, the medication cost can be saved, the environmental pollution can be reduced, and the method is an important means for comprehensively controlling pests.
Through retrieval, no literature on compounding and application of the trifluoro-benzene pyrimidine and the chlorfenapyr is found at present.
Disclosure of Invention
The invention aims to provide a compound pesticide containing the trifluoro-benzene pyrimidine and the chlorfenapyr, which has the effective components of the trifluoro-benzene pyrimidine and the chlorfenapyr, has high efficiency, safety, low toxicity and long duration, and is beneficial to the reasonable control of pests in paddy fields.
Through the intensive research on the combination of the trifluoro-benzene pyrimidine and the chlorfenapyr, the combination of the trifluoro-benzene pyrimidine and the chlorfenapyr in a certain proportion range has obvious synergistic effect on pests in paddy fields, and through further research, the purpose of the invention is realized through the following technical scheme:
a composite insecticide contains trifluorobenzene pyrimidine and chlorfenapyr, and its active components are trifluorobenzene pyrimidine and chlorfenapyr.
The weight ratio of the active ingredients of the trifluoro-benzene pyrimidine to the chlorfenapyr is 10: 1-1: 10.
Preferably, the weight ratio of the trifluoro-benzene pyrimidine to the chlorfenapyr is 3: 1-1: 3.
The weight percentage content of the active ingredients of the trifluoro-benzene pyrimidine and the chlorfenapyr in the composite bactericide is 5-80%.
The above active ingredients, trifluoropyrimidine and chlorfenapyr, are well known insecticides and are commercially available from various sources.
Besides the active ingredients of the trifluoropyrimidine and the chlorfenapyr, the compound pesticide also comprises a carrier and an auxiliary agent which are allowable in pesticides so as to be prepared into a suspending agent, a dispersible oil suspending agent, a wettable powder, a water dispersible granule, an emulsion in water and a microemulsion.
The carrier is one or more of water, solvent and filler.
The solvent is selected from one or a mixture of more of N, N-dimethylformamide, cyclohexanone, No. 150 solvent oil, No. 200 solvent oil, dimethyl sulfoxide, ethanol, trimethyl cyclohexanone, N-octyl pyrrolidone, N-methyl pyrrolidone, propanol, butanol, ethylene glycol, diethylene glycol, ethylene glycol methyl ether, butyl ether, vegetable oil, mineral oil, ethyl acetate or acetonitrile.
The filler is selected from one or a mixture of more of kaolin, diatomite, bentonite, attapulgite, white carbon black, starch or light calcium carbonate.
The auxiliary agent at least comprises a surfactant. The surfactant can be one or more of emulsifier, dispersant, wetting agent or penetrant, and can be nonionic or anionic, or can be a combination of the two types.
The emulsifier is selected from one or a mixture of more than one of calcium dodecyl benzene sulfonate, fatty acid polyoxyethylene ether, alkylphenol polyoxyethylene ether sulfosuccinate, styrylphenol polyoxyethylene ether, nonylphenol polyoxyethylene ether, castor oil polyoxyethylene ether, fatty acid polyoxyethylene ester, span series (sorbitan monostearate), tween series (sorbitan fatty acid ester polyoxyethylene ether) or AEO series (fatty alcohol polyoxyethylene ether polyoxyethylene fatty alcohol ether) in any ratio.
The dispersing agent is selected from one or a mixture of a plurality of polycarboxylate, lignosulfonate, alkylphenol polyoxyethylene ether formaldehyde condensate sulfate, calcium alkylbenzene sulfonate, naphthalene sulfonic acid formaldehyde condensate sodium salt, alkylphenol polyoxyethylene ether, fatty amine polyoxyethylene ether, fatty acid polyoxyethylene ether or glycerin fatty acid ester polyoxyethylene ether.
The wetting agent is selected from one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, nekal BX, wetting penetrant F, saponin powder, silkworm excrement or soapberry powder.
The penetrating agent is selected from one or a mixture of more of penetrating agent JFC (fatty alcohol-polyoxyethylene ether), penetrating agent T (diisooctyl maleate sulfonate), azone and organic silicon.
According to different use occasions and requirements, the composite insecticidal and acaricidal agent can also be added with an antifreezing agent, a thickening agent, a stabilizing agent, a disintegrating agent, a defoaming agent and other functional auxiliary agents.
The thickening agent is selected from one or a mixture of more of gelatin, sodium carboxymethylcellulose, hydroxyethyl cellulose, sodium polyacrylate, modified starch, xanthan gum, bentonite, silicon dioxide and magnesium aluminum silicate.
The antifreezing agent is a mixture consisting of one or more of ethylene glycol, propylene glycol, glycerol or urea.
The defoaming agent is selected from one or a mixture of more of silicone oil, silicone compounds, C10-C20 saturated fatty acid compounds or C8-C10 fatty alcohol compounds.
The disintegrating agent is selected from one or more of bentonite, urea, ammonium sulfate, aluminum chloride, low-substituted hydroxypropyl cellulose, lactose, citric acid, succinic acid or sodium bicarbonate.
The stabilizer is selected from one or more of epoxidized soybean oil, epichlorohydrin, BHT, ethyl acetate, sodium citrate and triphenyl phosphate.
The above-mentioned substances are all known to those skilled in the art and are commercially available.
The compound pesticide provided by the invention is mainly used for preventing and treating pests in paddy fields such as rice planthopper, rice leaf roller, rice planthopper, beet armyworm and prodenia litura in paddy fields, tobacco, rice, melons and fruits and flowers, and has very obvious prevention and treatment effects.
The invention also aims to provide a preparation method of the compound pesticide containing the trifluoro-benzene pyrimidine and the chlorfenapyr.
In order to achieve the purpose, the invention adopts the following technical scheme:
weighing the components according to the formula proportion, mixing the effective components of chlorfenapyr and trichlorobenzene pyrimidine with other wetting agents, dispersing agents, thickening agents, antifreezing agents, preservatives and water, carrying out sand grinding treatment for 2-3 hours after shearing, then adding the defoaming agent, and continuing shearing to prepare the suspending agent product.
Preferably, the sanding treatment adopts a horizontal type sanding machine.
Specifically, the main equipment comprises a mixer, a shearing machine and a horizontal sand mill.
A preparation method of a compound pesticide containing trifluoro-benzene pyrimidine and chlorfenapyr comprises the steps of weighing according to the formula proportion, adding effective components of chlorfenapyr and trifluoro-benzene pyrimidine into a carrier, adding a surfactant and other functional auxiliaries, mixing, carrying out air flow crushing, and mixing to obtain wettable powder.
Specifically, the main equipment is a mixer and a jet mill.
Weighing the active ingredients of the chlorfenapyr and the trifloxystrobin according to the formula proportion, adding the active ingredients of the chlorfenapyr and the trifloxystrobin into a carrier, adding a surfactant and other functional auxiliaries, mixing, carrying out air flow crushing, adding 10-25% of water, kneading, granulating, drying and screening to obtain the water dispersible granule product.
A preparation method of a compound pesticide containing trifluorfenapyr pyrimidine and chlorfenapyr comprises the steps of weighing according to the formula proportion, adding effective components of chlorfenapyr and trifluorfenapyr into a carrier, adding a surfactant and other functional auxiliaries into the carrier, mixing, carrying out air flow crushing, spraying water in a boiling granulator, granulating, drying, and screening to obtain a water dispersible granule product.
The main equipment comprises a mixer, a jet mill, a kneader, an extrusion granulator, a drying room or a fluidized bed for drying, or a boiling granulator and a sieving machine.
The compound pesticide provided by the invention has the following beneficial effects:
1. the synergistic effect is obvious, and the activity of each component is not simply added, but the obvious synergistic effect is achieved.
2. The field dosage of the active ingredients is reduced, the production and use cost is reduced, the pesticide residue and the environmental pollution are reduced, and the harm to beneficial organisms is reduced.
3. The two active ingredients in the compound pesticide have different action mechanisms, so that the single selection pressure on pests in the paddy field is reduced, and the generation of the resistance of the paddy field is overcome and the generation speed of the resistance of nematodes is delayed.
4. The compound pesticide can thoroughly prevent and control the pests in the paddy field in the whole crop growth period, has long efficacy duration, and is an important means for preventing and controlling the pests of the crops.
In conclusion, the invention meets the requirement of current production of green pollution-free agricultural products.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
1. Suspending agent
The preparation method comprises the following steps: according to the formula proportion of the following examples, the active ingredients of the trifluoro-benzene pyrimidine and the chlorfenapyr are mixed with other wetting agents, dispersing agents, thickening agents, antifreezing agents, preservatives and water, the mixture is added into a horizontal sand mill for sanding for 2 to 3 hours after being sheared, and then the defoaming agent is added for continuous shearing to prepare the suspending agent product.
Example 1: (20% Trifluoropyrimidine chlorfenapyr suspension)
The formula is as follows: chlorfenapyr, 10%; trifluoro-benzene pyrimidine, 10%; wetting dispersant block polyether, 3%; dispersant carboxylate, 2%; wetting agent methyl naphthalene yellow salt formaldehyde condensation compound, 1%; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.2% and 2% respectively; 4% of antifreeze propylene glycol; 0.2% of preservative; 0.2% of defoaming agent; water and the balance.
Example 2: (22% Trifluoropyrimidine chlorfenapyr suspension)
The formula is as follows: chlorfenapyr, 20%; trifluoro-benzene pyrimidine, 2%; wetting dispersant block polyether, 3%; dispersant carboxylate, 2%; wetting agent methyl naphthalene yellow salt formaldehyde condensation compound, 1%; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.2% and 2% respectively; 4% of antifreeze propylene glycol; 0.2% of preservative; 0.2% of defoaming agent; water and the balance.
Example 3: (24% Trifluoropyrimidine chlorfenapyr suspension)
The formula is as follows: chlorfenapyr, 20%; trifluoro-benzene pyrimidine, 4%; wetting dispersant block polyether, 3%; dispersant carboxylate, 2%; wetting agent methyl naphthalene yellow salt formaldehyde condensation compound, 1%; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.2% and 2% respectively; 4% of antifreeze propylene glycol; 0.2% of preservative; 0.2% of defoaming agent; water and the balance.
2. Wettable powder
The preparation method comprises the following steps: according to the formula proportion of the embodiment, the effective components of the chlorfenapyr and the trifluoro-benzene pyrimidine are added into the carrier, and the surfactant and other functional additives are added into the carrier, mixed, crushed by air flow and then mixed to prepare the wettable powder.
Example 4: (25% trifluorinopyrimidine chlorfenapyr wettable powder)
The formula is as follows: chlorfenapyr, 10%; trifluoro-benzene pyrimidine, 15%; wetting agent sodium dodecyl sulfate, 3%; 5% of dispersant calcium lignosulfonate; dispersing agent sodium dodecyl sulfate, 2%; 12% of filler white carbon black, and the balance of filler kaolin.
Example 5: (20% trifluorinopyrimidine chlorfenapyr wettable powder)
The formula is as follows: chlorfenapyr, 15%; trifluoro-benzene pyrimidine, 5%; wetting agent sodium dodecyl sulfate, 3%; 5% of dispersant calcium lignosulfonate; dispersing agent sodium dodecyl sulfate, 2%; 12% of filler white carbon black, and the balance of filler kaolin.
3. Water dispersible granule
The preparation method comprises the following steps: adding effective components of chlorfenapyr and trifluoropyrimidine into a carrier according to the formula proportion of the embodiment, adding a surfactant and other functional auxiliaries, mixing, carrying out jet milling, adding 10-25% of water, kneading, granulating, drying and screening to obtain a water dispersible granule product; or spraying water to the pulverized powder in a boiling granulator, granulating, drying, and sieving to obtain the final product.
Example 6: (30% trifluoro-benzene pyrimidine chlorfenapyr water dispersible granule)
The formula is as follows: chlorfenapyr, 20%; trifluoro-benzene pyrimidine, 10%; wetting agent sodium dodecylbenzene sulfonate, 4%; 4% of dispersant sodium lignosulfonate; 8% of dispersant alkyl naphthalene sulfonate formaldehyde condensate; attapulgite is filled, and the balance is.
Example 7: (20% Trifluoropyrimidine chlorfenapyr water dispersible granule)
The formula is as follows: 5% of chlorfenapyr; trifluoro-benzene pyrimidine, 15%; wetting agent sodium dodecylbenzene sulfonate, 4%; 4% of dispersant sodium lignosulfonate; 8% of dispersant alkyl naphthalene sulfonate formaldehyde condensate; attapulgite is filled, and the balance is.
Example 8: (24% Trifluoropyrimidine chlorfenapyr suspension)
The formula is as follows: 4% of chlorfenapyr; trifluoro-benzene pyrimidine, 20%; wetting dispersant block polyether, 3%; dispersant carboxylate, 2%; wetting agent methyl naphthalene yellow salt formaldehyde condensation compound, 1%; the thickening agent is selected from xanthan gum and aluminum magnesium silicate, and the using amounts are 0.2% and 2% respectively; 4% of antifreeze propylene glycol; 0.2% of preservative; 0.2% of defoaming agent; water and the balance.
Example 9: (22% Trifluoropyrimidine chlorfenapyr water dispersible granule)
The formula is as follows: chlorfenapyr, 2%; trifluoro-benzene pyrimidine, 20%; wetting agent sodium dodecylbenzene sulfonate, 4%; 4% of dispersant sodium lignosulfonate; 8% of dispersant alkyl naphthalene sulfonate formaldehyde condensate; attapulgite is filled, and the balance is.
In order to make the technical solution, purpose and advantages of the present invention more apparent, the present invention is described by the following embodiments, but the present invention is not limited to these examples. The effect experiment of the invention adopts a mode of combining indoor bioassay and field experiment.
Indoor toxicity assay
Measuring indoor toxicity, wherein the test medicament adopts 98 percent of chlorfenapyr technical and 95 percent of trifluoropyrimidine technical; the test target is rice planthopper, and uniform 3-instar larvae are picked for testing.
The test method comprises the following steps: dissolving the test reagent with acetone by a leaf soaking method, diluting into 5 series of concentration gradients, beating clean rice leaves into round pieces with diameter of about 2cm by a puncher, soaking the leaves into corresponding reagent treatment concentration, taking out after 10s, naturally drying, and placing the leaves in a culture dish padded with filter paper for moisturizing. Subsequently, 3-instar larvae of rice planthopper which had been starved for 4h were inoculated, 10 larvae were treated at each concentration, and the procedure was repeated 4 times. The control was treated with clean water. The culture dish is placed in an artificial climate box with the temperature of 25 +/-1 ℃, RH 75% and the ratio of 16L to 8D, the survival condition of 3-instar larvae is checked after 48 hours, and the death standard is that no obvious autonomous reaction occurs when the fine hairbrush touches the larvae. If the mortality rate of the control group is more than or equal to 10 percent, the test needs to be carried out again.
The joint mode of action was determined using the co-toxicity coefficient (CTC) method. The co-toxicity coefficient is calculated as follows: the virulence index (ATI) was measured as (standard agent LC 50/test agent LC50) × 100.
Theoretical virulence index (TTI) ═ a agent virulence index x percent of a in the mixture + B agent virulence index x percent of B in the mixture.
Co-toxicity coefficient (CTC) × 100 [ measured toxicity index (ATI) of the mixture)/Theoretical Toxicity Index (TTI) of the mixture ].
According to NY/T11547.7-2006 pesticide combination division standard: the co-toxicity coefficient (CTC) is more than or equal to 120 and shows a synergistic effect; the co-toxicity coefficient (CTC) is less than or equal to 80, and the antagonism is shown; 80 < co-toxicity coefficient (CTC) < 120 showed additive effects. The test results are shown in Table 1.
TABLE 1 indoor combined virulence determination of Chlorfenapyr and Triflufenapyr against Rice planthopper
As can be seen from the table 1, the composition disclosed by the embodiment of the invention has very high activity on rice planthoppers, and the co-toxicity coefficients of the chlorfenapyr and the trifluoro-benzene pyrimidine are both more than 120 within the ratio of 10: 1-1: 10, which indicates that the compound pesticide has a synergistic effect; the weight ratio is 3: 1-1: 3, the co-toxicity coefficient is more than 150, the synergistic effect is more obvious, and the rationality and feasibility of the combination of the chlorfenapyr and the trifluoro-benzene pyrimidine can be seen.
Pesticide effect test for preventing and controlling rice planthopper in field test
The test plot is flat, the management of fertilizer and water is good, the tested crop is No. 1 rice, and the pesticide is applied in the full-blown period of the low-age larvae of the rice planthoppers. The test shows that 20% chlorfenapyr-trifluoropyrimidine SC3000 times, 25% chlorfenapyr-trifluoropyrimidine WP3500 times, 30% chlorfenapyr-trifluoropyrimidine WG3500 times, contrast agent 10% chlorfenapyr 1200 times, 15% trifluoropyrimidine 1200 times and clear water contrast 6 treatments, the area of the cell is 20m24 replicates, randomized block permutation. Spraying by a knapsack manual sprayer with the spraying liquid amount of 750kg/hm2. And (3) adopting a fixed-point fixed-plant investigation method to investigate the number of larvae on 15 rice plants at fixed points in each cell. The population base number is investigated before pesticide application, the number of the live insects remained on the rice is investigated 1, 3 and 7 days after pesticide application, and the control effect of each treatment is calculated according to the population decline rate.
TABLE 2 field efficacy control results for rice planthopper by different treatments
The test results in Table 2 show that the control effect of the pesticide on rice planthopper after application is obviously higher than that of the control
The control effect of the pesticide rice planthopper is still over 90 percent 7 days after the pesticide is applied, which shows that the chlorfenapyr and trifluoro-benzene pyrimidine compound pesticide has obvious synergistic effect and the lasting time is obviously longer than that of a single pesticide. Experiments show that the compound pesticide obviously reduces the using amount of the pesticide, and reduces the production cost, pesticide residue and environmental pollution. In addition, field observation during the test period shows that the liquid medicine of each treatment of the medicament in the embodiment has no influence on the growth of the cucumber, is safe to the surrounding beneficial organisms and has good environmental compatibility. Therefore, the chlorfenapyr and the trifluoropyrimidine are ideal compound insecticidal products.
Claims (10)
1. The compound pesticide containing the trifluoro-benzene pyrimidine and the chlorfenapyr is characterized in that the effective components of the compound pesticide are the trifluoro-benzene pyrimidine and the chlorfenapyr.
2. The compound pesticide of claim 1, wherein the weight ratio of the active ingredients of the trifluoro-benzene pyrimidine to the chlorfenapyr is 10: 1-1: 10.
3. The compound pesticide of claim 2, wherein the weight ratio of the active ingredients of the trifluoro-benzene pyrimidine to the chlorfenapyr is 3: 1-1: 3.
4. The compound pesticide of claim 1, wherein the weight percentage of the active ingredients in the compound pesticide is 5-80%, and the balance is allowable carriers and auxiliary agents on pesticides.
5. The composite pesticide of claim 4, wherein the carrier is one or more of water, a solvent and a filler.
6. The composite pesticide of claim 4, wherein the pesticide is in the form of suspending agent, dispersible oil suspending agent, wettable powder, water dispersible granule, emulsion in water, or microemulsion.
7. The composite pesticide according to claim 1, which is used for controlling pests in paddy fields.
8. A preparation method of a compound insecticide containing trifluoro-benzene pyrimidine and chlorfenapyr is characterized in that the compound insecticide containing the trifluoro-benzene pyrimidine and the chlorfenapyr is weighed according to the formula proportion of any one of the claims 1 to 6, the effective components of the chlorfenapyr and the trifluoro-benzene pyrimidine are mixed with other wetting agents, dispersing agents, thickening agents, antifreezing agents, preservatives and water, after shearing, sanding treatment is carried out for 2 to 3 hours, then defoaming agents are added, and shearing is continued, so that a suspending agent product is prepared.
9. A process for preparing a composite insecticide containing trifluoropyrimidine and chlorfenapyr includes such steps as proportionally mixing active components, chlorfenapyr and trifluoropyrimidine in carrier, adding surfactant and other functional assistants, mixing, airflow pulverizing, and mixing.
10. A preparation method of a compound pesticide containing trifluorfenapyr pyrimidine and chlorfenapyr is characterized in that the compound pesticide is weighed according to the formula proportion of any one of claims 1 to 6, the effective components of chlorfenapyr and trifluorfenapyr pyrimidine are added into a carrier, a surfactant and other functional auxiliaries are added into the carrier, the carrier and the carrier are mixed, 10 to 25 percent of water is added after the carrier is crushed by air flow, and then the water dispersible granule product is prepared after kneading, granulation, drying and screening; or spraying water to the pulverized powder in a boiling granulator, granulating, drying, and sieving to obtain the final product.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102665415A (en) * | 2009-08-05 | 2012-09-12 | 杜邦公司 | Mixtures of mesoionic pesticides |
| CN104430365A (en) * | 2013-09-23 | 2015-03-25 | 陕西韦尔奇作物保护有限公司 | Efficient insecticidal composition containing trifluorobenzene pyrimidine |
| CN103459387B (en) * | 2010-12-29 | 2015-08-26 | 杜邦公司 | Mesoionic pyrido [1,2-A] pyrimidine sterilant |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102665415A (en) * | 2009-08-05 | 2012-09-12 | 杜邦公司 | Mixtures of mesoionic pesticides |
| CN103459387B (en) * | 2010-12-29 | 2015-08-26 | 杜邦公司 | Mesoionic pyrido [1,2-A] pyrimidine sterilant |
| CN104430365A (en) * | 2013-09-23 | 2015-03-25 | 陕西韦尔奇作物保护有限公司 | Efficient insecticidal composition containing trifluorobenzene pyrimidine |
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