CN110507413A - A microwave therapy instrument with controllable effective thermal zone of ablation - Google Patents
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Abstract
本发明公开一种消融有效热区可控的微波治疗仪，其包括：915MHz微波信号发生器组件、2450MHz微波发生器组件、微波功率放大器组件、微波功率检测器组件、消融针连接控制模块组件、微波同轴连接器组件、915MHz水冷微波消融针组件、2450MHz水冷微波消融针组件、直流电源、控制器组件、降温模块组件、消融针测温模块、数据库模块。该治疗仪微波屏蔽性能好、电气安全性高、微波功率低延迟精准可控，且具有两种频率四个独立消融通道，必要时可以采取双针甚至三针组合消融，尤其适用于难于治疗的单体大肿瘤。本仪器还可以与本地数据库和互联网数据库进行比对，进一步矫正术中消融策略，从而达到消融热区可控等目标。
The invention discloses a microwave therapy instrument with controllable effective thermal zone of ablation, which comprises: a 915MHz microwave signal generator component, a 2450MHz microwave generator component, a microwave power amplifier component, a microwave power detector component, an ablation needle connection control module component, Microwave coaxial connector assembly, 915MHz water-cooled microwave ablation needle assembly, 2450MHz water-cooled microwave ablation needle assembly, DC power supply, controller assembly, cooling module assembly, ablation needle temperature measurement module, and database module. The therapeutic device has good microwave shielding performance, high electrical safety, low delay of microwave power, precise controllability, and four independent ablation channels with two frequencies. If necessary, double needle or even three needle combined ablation can be used, especially suitable for difficult-to-treat patients. Single large tumor. The instrument can also be compared with the local database and the Internet database to further correct the intraoperative ablation strategy, so as to achieve the goal of controllable ablation hot zone.
Description
技术领域technical field
本发明属于医疗器械领域，具体涉及一种消融有效热区可控的微波治疗仪。The invention belongs to the field of medical equipment, and in particular relates to a microwave therapeutic instrument with controllable effective thermal zone of ablation.
背景技术Background technique
微波消融技术已经广泛应用于临床医学中，通过微波源控制其输出功率来达到尖端升温效果，使病灶处肿瘤细胞蛋白质变性凝固，达到杀死肿瘤细胞的治疗效果。相较于大范围的切除手术以及化疗放疗带来的强烈副作用，微波消融技术可以显著提高患者治疗效率和生活质量。微波消融技术的成熟与完善将会为肿瘤的治疗开辟新的模式。Microwave ablation technology has been widely used in clinical medicine. The output power of the microwave source is controlled to achieve the effect of tip heating, denature and solidify the tumor cell protein in the lesion, and achieve the therapeutic effect of killing tumor cells. Compared with extensive resection and strong side effects caused by chemotherapy and radiotherapy, microwave ablation technology can significantly improve the treatment efficiency and quality of life of patients. The maturity and perfection of microwave ablation technology will open up a new model for tumor treatment.
但是，微波消融技术在临床治疗中详细治疗参数临床进行肿瘤微波消融治疗时主要凭借医生的临床经验来设计治疗方案，其个人主观因素对整个治疗过程及效果影响较大，在实际消融过程中存在着消融范围小、消融范围不可控的难题，另外，由于消融针中心碳化等因素的影响，尤其对肝癌、肺癌等大肿瘤一次性消融成功率很低，导致手术失败。或者消融范围过大导致正常组织受到损伤。However, the detailed treatment parameters of microwave ablation technology in clinical treatment are mainly based on the doctor's clinical experience to design the treatment plan when microwave ablation treatment of tumors. The personal subjective factors have a great influence on the whole treatment process and effect. In the actual ablation process, there are In addition, due to the carbonization of the center of the ablation needle and other factors, the success rate of one-time ablation is very low, especially for large tumors such as liver cancer and lung cancer, resulting in surgical failure. Or the ablation range is too large to cause damage to normal tissues.
发明内容Contents of the invention
本发明针对现有技术的不足，提出一种消融有效热区可控的微波治疗仪，通过对单路消融的功率以及波形进行控制，对于特别大的肿瘤采取多路消融针组合以增加实际有效消融范围，能够在微波消融控制时有效热区以及且能够有效增大消融范围。Aiming at the deficiencies of the prior art, the present invention proposes a microwave therapeutic apparatus with controllable effective thermal zone of ablation. By controlling the power and waveform of single-channel ablation, a multi-channel ablation needle combination is adopted for particularly large tumors to increase the actual effective rate. The ablation range can effectively increase the ablation range and the effective hot zone during microwave ablation control.
本发明的目的通过如下的技术方案来实现：The purpose of the present invention is achieved through the following technical solutions:
一种消融有效热区可控的微波治疗仪，其特征在于，该微波治疗仪包括微波源组件、微波同轴连接器组件、水冷微波消融针组件、控制器组件、降温模块组件、消融针测温模块、数据库模块；A microwave therapeutic apparatus with controllable effective thermal zone of ablation, characterized in that the microwave therapeutic apparatus includes a microwave source assembly, a microwave coaxial connector assembly, a water-cooled microwave ablation needle assembly, a controller assembly, a cooling module assembly, an ablation needle measurement temperature module, database module;
所述的微波源组件包括依次连接的微波信号发生器组件、微波功率放大器组件、微波功率检测器组件、消融针连接控制模块组件，且所述的微波信号发生器组件包括两路915MHz微波信号发生器和两路2450MHz微波发生器；The microwave source assembly includes a microwave signal generator assembly, a microwave power amplifier assembly, a microwave power detector assembly, and an ablation needle connection control module assembly connected in sequence, and the microwave signal generator assembly includes two 915MHz microwave signal generators device and two 2450MHz microwave generators;
所述的微波功率放大器组件也为四路，分别用于对每一路微波信号进行功率放大处理；The microwave power amplifier assembly also has four channels, which are respectively used to perform power amplification processing on each channel of microwave signals;
所述的微波功率检测器组件也为四路，分别用于对每一路微波的正向功率以及反向功率进行检测，并将数据发送给所述的控制器组件；The microwave power detector assembly also has four channels, which are respectively used to detect the forward power and reverse power of each microwave, and send the data to the controller assembly;
所述的消融针连接控制模块组件也为四路，所述的微波同轴连接器组件也为四路，所述的水冷微波消融针组件包括两个915MHz水冷微波消融针和两个2450MHz水冷微波消融针，三个组件的每一路也依次对应连接，所述的消融针连接控制模块组件用于对微波消融针进行在线识别和进行相关的控制，并对所述的水冷模块进行控制，从而降低微波消融针针管的温度；通过调整微波同轴连接器可达到整体的最佳阻抗匹配；The ablation needle connection control module assembly is also four-way, the microwave coaxial connector assembly is also four-way, and the water-cooled microwave ablation needle assembly includes two 915MHz water-cooled microwave ablation needles and two 2450MHz water-cooled microwave The ablation needle, each of the three components is also connected in turn, the ablation needle connection control module assembly is used for online identification and related control of the microwave ablation needle, and controls the water cooling module, thereby reducing The temperature of the microwave ablation needle tube; the overall best impedance matching can be achieved by adjusting the microwave coaxial connector;
所述的降温模块组件为水冷模块，其两端分别与所述的消融针连接控制模块组件和所述的水冷微波消融针组件连接，用于在所述的消融针连接控制模块组件的控制下对所述的水冷微波消融针组件进行水冷；The cooling module assembly is a water-cooling module, and its two ends are respectively connected to the ablation needle connection control module assembly and the water-cooled microwave ablation needle assembly, for use under the control of the ablation needle connection control module assembly Water-cooling the water-cooled microwave ablation needle assembly;
所述的消融针测温模块的两端分别与所述的水冷微波消融针组件和所述的控制器组件相连，用于检测所述的水冷微波消融针组件的温度，并将其反馈给所述的控制器组件；The two ends of the ablation needle temperature measurement module are respectively connected with the water-cooled microwave ablation needle assembly and the controller assembly for detecting the temperature of the water-cooled microwave ablation needle assembly and feeding it back to the described controller components;
所述的控制器组件为总控制器，控制微波信号发生器的开闭，进而控制微波波形和消融时间；根据需要启用频率发生器；控制微波功率放大器组件，进而控制微波功率；接收微波功率检测器组件发送的反馈数据，进而初步控制微波消融有效热区的范围；控制风冷散热模块，进而对微波治疗仪温度进行调节防止出现微波治疗仪温度过高；和消融针连接控制模块组件进行通信，从而根据需要对消融针进行控制；读取微波消融针测温模块的温度数据，从而对消融针连接控制模块进行通信控制，经过一定的算法反馈控制处理之后，进一步控制整体的有效消融范围；The controller component is a general controller, which controls the opening and closing of the microwave signal generator, and then controls the microwave waveform and ablation time; enables the frequency generator as required; controls the microwave power amplifier component, and then controls the microwave power; receives microwave power detection The feedback data sent by the microwave therapy device components, and then preliminarily control the range of the effective heat zone of microwave ablation; control the air-cooled heat dissipation module, and then adjust the temperature of the microwave therapy device to prevent the temperature of the microwave therapy device from being too high; communicate with the ablation needle connection control module components , so as to control the ablation needle according to the needs; read the temperature data of the microwave ablation needle temperature measurement module, so as to communicate with the ablation needle connection control module, and after a certain algorithm feedback control process, further control the overall effective ablation range;
所述的数据库模块包括本地数据库和互联网数据库，所述的本地数据库用于存储本地的消融案例和术前规划；所述的互联网数据库用于存储不同型号的消融针以往的消融案例，从而实现数据共享。The database module includes a local database and an Internet database, and the local database is used to store local ablation cases and preoperative planning; the Internet database is used to store previous ablation cases of different types of ablation needles, thereby realizing data shared.
进一步地，所述的控制器组件还包括实体按钮控制或通过计算机上位机程序，从而实现对所述的总控制器的控制。Further, the controller assembly also includes physical button control or a computer host computer program, so as to realize the control of the general controller.
进一步地，所述的降温模块组件还包括风冷散热模块，该模块与所述的控制器组件和微波源组件相连，用于对整个微波治疗仪进行降温。Further, the cooling module assembly also includes an air-cooling heat dissipation module, which is connected with the controller assembly and the microwave source assembly, and is used for cooling the entire microwave therapeutic apparatus.
进一步地，还包括直流电源，用于为整个微波治疗仪供电。Further, it also includes a direct current power supply for powering the whole microwave therapeutic apparatus.
本发明的有益效果如下：The beneficial effects of the present invention are as follows:
本发明的微波治疗仪具有更好的稳定性以及可控性，尤其是对于消融有效范围可以进行更加有效的控制，对于大肿瘤治疗，可以采用多路微波消融针进行协调消融，从而达到更大的更好的消融范围，从而达到一次手术治疗肿瘤的目的。The microwave therapeutic apparatus of the present invention has better stability and controllability, especially for more effective control of the effective range of ablation, and for the treatment of large tumors, multi-channel microwave ablation needles can be used for coordinated ablation, thereby achieving greater A better ablation range, so as to achieve the purpose of one operation to treat the tumor.
附图说明Description of drawings
图1为本发明实施例提供的一种消融有效热区可控的微波治疗仪的结构示意图；Fig. 1 is a schematic structural diagram of a microwave therapeutic apparatus with controllable effective thermal zone of ablation provided by an embodiment of the present invention;
图中，100-微波源组件；110-微波信号发生器组件；120-微波功率放大器组件；130-微波功率检测器组件；140-消融针连接控制模块组件；200-微波同轴连接器组件；210-微波同轴连接器A；220-微波同轴连接器B；230-微波同轴连接器C；240-微波同轴连接器D；300-水冷微波消融针组件；310-水冷微波消融针A；320-水冷微波消融针B；330-水冷微波消融针C；340-水冷微波消融针D；400-控制器组件；410-总控制器；420-实体控制按钮；430-计算机上位机控制程序；500-降温模块组件；510-风冷散热模块；520水冷模块；600-直流电源；700-消融针测温模块；800-数据库模块；810-本地数据库；820-互联网数据库。In the figure, 100-microwave source component; 110-microwave signal generator component; 120-microwave power amplifier component; 130-microwave power detector component; 140-ablation needle connection control module component; 200-microwave coaxial connector component; 210-Microwave coaxial connector A; 220-Microwave coaxial connector B; 230-Microwave coaxial connector C; 240-Microwave coaxial connector D; 300-Water-cooled microwave ablation needle assembly; 310-Water-cooled microwave ablation needle A; 320-water-cooled microwave ablation needle B; 330-water-cooled microwave ablation needle C; 340-water-cooled microwave ablation needle D; 400-controller component; 410-master controller; 420-physical control button; 430-computer host computer control Program; 500-cooling module components; 510-air cooling module; 520 water cooling module; 600-DC power supply; 700-ablation needle temperature measurement module; 800-database module; 810-local database; 820-Internet database.
具体实施方式Detailed ways
下面根据附图和优选实施例详细描述本发明，本发明的目的和效果将变得更加明白，应当理解，此处所描述的具体实施例仅仅用以解释本发明，并不用于限定本发明。The present invention will be described in detail below with reference to the accompanying drawings and preferred embodiments, and the purpose and effect of the present invention will become clearer. It should be understood that the specific embodiments described here are only used to explain the present invention and are not intended to limit the present invention.
如图1所示，本发明的微波治疗仪包括微波源组件100、微波同轴连接器组件200、水冷微波消融针组件300、控制器组件400、降温模块组件500、直流电源600、消融针测温模块700、数据库模块800，其中，As shown in Figure 1, the microwave therapeutic apparatus of the present invention includes a microwave source assembly 100, a microwave coaxial connector assembly 200, a water-cooled microwave ablation needle assembly 300, a controller assembly 400, a cooling module assembly 500, a DC power supply 600, an ablation needle assembly Temperature module 700, database module 800, wherein,
微波源组件100包括微波信号发生器组件110、微波功率放大器组件120、微波功率检测器组件130、消融针连接控制模块组件140；The microwave source assembly 100 includes a microwave signal generator assembly 110, a microwave power amplifier assembly 120, a microwave power detector assembly 130, and an ablation needle connection control module assembly 140;
微波信号发生器组件110包括两路915MHz微波信号发生器A、B和两路2450MHz微波发生器C、D；微波功率放大器组件120对应地包括四个微波功率放大器A、B、C、D，微波功率检测器组件130对应地包括四个微波功率检测器A、B、C、D，消融针连接控制模块组件140也包括四个消融针连接控制模块A、B、C、D；Microwave signal generator assembly 110 includes two-way 915MHz microwave signal generator A, B and two-way 2450MHz microwave generator C, D; Microwave power amplifier assembly 120 includes four microwave power amplifiers A, B, C, D correspondingly, microwave The power detector assembly 130 correspondingly includes four microwave power detectors A, B, C, and D, and the ablation needle connection control module assembly 140 also includes four ablation needle connection control modules A, B, C, and D;
微波同轴连接器组件200包括四个微波同轴连接器A、B、C、D，水冷微波消融针组件300包括两路915MHz水冷微波消融针A、B和两路2450MHz水冷微波消融针C、D；The microwave coaxial connector assembly 200 includes four microwave coaxial connectors A, B, C, D, and the water-cooled microwave ablation needle assembly 300 includes two 915MHz water-cooled microwave ablation needles A, B and two 2450MHz water-cooled microwave ablation needles C, D;
控制器组件400包括总控制器410、实体控制按钮420和计算机上位机控制程序430；The controller assembly 400 includes a general controller 410, physical control buttons 420 and a computer host computer control program 430;
降温模块组件500包括风冷散热模块510、水冷模块520；The cooling module assembly 500 includes an air cooling module 510 and a water cooling module 520;
数据库模块800包括本地数据库810和互联网数据库820。The database module 800 includes a local database 810 and an internet database 820 .
如图1所示，将直流电源600给微波源组件100、控制器组件400上电，总控制器410控制风冷散热模块510对微波源组件100进行风冷散热。As shown in FIG. 1 , the microwave source assembly 100 and the controller assembly 400 are powered on by the DC power supply 600 , and the general controller 410 controls the air-cooling heat dissipation module 510 to perform air-cooling and heat dissipation on the microwave source assembly 100 .
根据需要通过实体控制按钮420或者计算机上位机控制程序430对总控制器410发出指令，控制微波信号发生器组件110中的不同频率的微波信号发生器开启或者关闭。According to needs, the physical control button 420 or the computer host computer control program 430 sends instructions to the general controller 410 to control the microwave signal generators of different frequencies in the microwave signal generator assembly 110 to be turned on or off.
微波信号发生器组件110中的输出端和对应通路的微波功率放大器组件120中的输入端连接，将微波信号转化成一定功率的微波。控制器组件400可以控制微波功率放大器组件120的功率大小。The output terminal of the microwave signal generator component 110 is connected to the input terminal of the microwave power amplifier component 120 of the corresponding channel, and the microwave signal is converted into microwaves of a certain power. The controller component 400 can control the power of the microwave power amplifier component 120 .
微波功率放大器组件120中的输出端和对应通路的微波功率检测器组件130的输入端进行连接，微波功率检测器组件130的输出端数据送到总控制器410中。The output terminal of the microwave power amplifier component 120 is connected to the input terminal of the microwave power detector component 130 of the corresponding path, and the data of the output terminal of the microwave power detector component 130 is sent to the general controller 410 .
微波功率检测器组件130的输出端和对应通路的消融针连接控制模块组件140的输入端连接，消融针连接控制模块组件140的输出端和总控制器410进行连接，消融针连接控制模块组件140的输出端和水冷模块520输入端进行连接，用来降低消融针针管的温度。The output end of the microwave power detector assembly 130 is connected to the input end of the ablation needle connection control module assembly 140 of the corresponding channel, the output end of the ablation needle connection control module assembly 140 is connected to the general controller 410, and the ablation needle connection control module assembly 140 The output end of the water cooling module 520 is connected to the input end to reduce the temperature of the ablation needle tube.
消融针连接控制模块组件140的输出端和对应通路的微波同轴连接器组件200输入端进行连接。The ablation needle is connected to the output end of the control module assembly 140 and the input end of the microwave coaxial connector assembly 200 corresponding to the channel.
微波同轴连接器组件200的输出端和对应通路的水冷微波消融针组件300的输入端进行连接，水冷微波消融针组件300的输出端和消融针测温模块700相连，消融针测温模块700又和控制器组件400进行连接，将温度数据送到410总控制器中，总控制器410根据一定的算法将控制相应通路中的微波信号发生器组件110的启停、调节微波功率放大器120的功率大小、控制消融针连接控制模块组件140，从而进一步对有效消融热区范围进行控制，达到更好的消融治疗效果。The output end of the microwave coaxial connector assembly 200 is connected to the input end of the water-cooled microwave ablation needle assembly 300 corresponding to the channel, the output end of the water-cooled microwave ablation needle assembly 300 is connected to the ablation needle temperature measurement module 700, and the ablation needle temperature measurement module 700 It is connected with the controller assembly 400, and the temperature data is sent to the 410 general controller. The general controller 410 will control the start and stop of the microwave signal generator assembly 110 in the corresponding path and adjust the microwave power amplifier 120 according to a certain algorithm. Power level and control The ablation needle is connected to the control module assembly 140, so as to further control the range of the effective ablation hot zone and achieve a better ablation treatment effect.
总控制器410一方面根据术前规划进行实施控制；另外一方面总控制器410将本次做手术的数据按照一定的时间间隔与本地数据库810进行比对，根据一定的模型进行实时调整消融策略；另外一方面，手术完成之后，将本次手术数据进行数据整理然后备份到互联网数据库820，互联网数据库820是所有使用本仪器所共享的数据库，数据经过模型处理，符合国家隐私标准。On the one hand, the general controller 410 performs control according to the preoperative planning; on the other hand, the general controller 410 compares the data of this operation with the local database 810 at a certain time interval, and adjusts the ablation strategy in real time according to a certain model On the other hand, after the operation is completed, the operation data is sorted and then backed up to the Internet database 820. The Internet database 820 is a database shared by all the instruments. The data is processed by the model and meets the national privacy standards.
本领域普通技术人员可以理解，以上所述仅为发明的优选实例而已，并不用于限制发明，尽管参照前述实例对发明进行了详细的说明，对于本领域的技术人员来说，其依然可以对前述各实例记载的技术方案进行修改，或者对其中部分技术特征进行等同替换。凡在发明的精神和原则之内，所做的修改、等同替换等均应包含在发明的保护范围之内。Those of ordinary skill in the art can understand that the above description is only a preferred example of the invention, and is not intended to limit the invention. Although the invention has been described in detail with reference to the foregoing examples, for those skilled in the art, it can still be understood. The technical solutions described in the foregoing examples are modified, or some of the technical features are equivalently replaced. All modifications, equivalent replacements, etc. within the spirit and principles of the invention shall be included in the scope of protection of the invention.
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