CN108770861A - A kind of composition pesticide containing Hexythiazox and fluazinam - Google Patents
A kind of composition pesticide containing Hexythiazox and fluazinam Download PDFInfo
- Publication number
- CN108770861A CN108770861A CN201810700542.8A CN201810700542A CN108770861A CN 108770861 A CN108770861 A CN 108770861A CN 201810700542 A CN201810700542 A CN 201810700542A CN 108770861 A CN108770861 A CN 108770861A
- Authority
- CN
- China
- Prior art keywords
- fluazinam
- hexythiazox
- composition
- mite
- composition pesticide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- UZCGKGPEKUCDTF-UHFFFAOYSA-N fluazinam Chemical compound [O-][N+](=O)C1=CC(C(F)(F)F)=C(Cl)C([N+]([O-])=O)=C1NC1=NC=C(C(F)(F)F)C=C1Cl UZCGKGPEKUCDTF-UHFFFAOYSA-N 0.000 title claims abstract description 47
- 239000005780 Fluazinam Substances 0.000 title claims abstract description 46
- XGWIJUOSCAQSSV-XHDPSFHLSA-N (S,S)-hexythiazox Chemical compound S([C@H]([C@@H]1C)C=2C=CC(Cl)=CC=2)C(=O)N1C(=O)NC1CCCCC1 XGWIJUOSCAQSSV-XHDPSFHLSA-N 0.000 title claims abstract description 44
- 239000005661 Hexythiazox Substances 0.000 title claims abstract description 44
- 239000000203 mixture Substances 0.000 title claims abstract description 43
- 239000000575 pesticide Substances 0.000 title claims abstract description 22
- 239000004480 active ingredient Substances 0.000 claims abstract description 5
- 230000000694 effects Effects 0.000 abstract description 19
- 241000488581 Panonychus citri Species 0.000 abstract description 12
- 241000607479 Yersinia pestis Species 0.000 abstract description 5
- 239000000470 constituent Substances 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 15
- 239000000375 suspending agent Substances 0.000 description 12
- 239000003995 emulsifying agent Substances 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 8
- 230000002265 prevention Effects 0.000 description 8
- 230000002195 synergetic effect Effects 0.000 description 8
- 239000003795 chemical substances by application Substances 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 229940051841 polyoxyethylene ether Drugs 0.000 description 6
- 229920000056 polyoxyethylene ether Polymers 0.000 description 6
- 238000012360 testing method Methods 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 241000196324 Embryophyta Species 0.000 description 5
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 5
- 239000008367 deionised water Substances 0.000 description 5
- 229910021641 deionized water Inorganic materials 0.000 description 5
- 239000002270 dispersing agent Substances 0.000 description 5
- 239000004530 micro-emulsion Substances 0.000 description 5
- 239000002904 solvent Substances 0.000 description 5
- -1 thiazolidine ketone Chemical class 0.000 description 5
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 description 4
- 241000488583 Panonychus ulmi Species 0.000 description 4
- 230000000895 acaricidal effect Effects 0.000 description 4
- 239000000642 acaricide Substances 0.000 description 4
- 239000002518 antifoaming agent Substances 0.000 description 4
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 description 4
- 230000003129 miticidal effect Effects 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- 239000000080 wetting agent Substances 0.000 description 4
- 241000207199 Citrus Species 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 235000020971 citrus fruits Nutrition 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 230000002045 lasting effect Effects 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- 239000003381 stabilizer Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- LRWZZZWJMFNZIK-UHFFFAOYSA-N 2-chloro-3-methyloxirane Chemical compound CC1OC1Cl LRWZZZWJMFNZIK-UHFFFAOYSA-N 0.000 description 2
- DUIOKRXOKLLURE-UHFFFAOYSA-N 2-octylphenol Chemical compound CCCCCCCCC1=CC=CC=C1O DUIOKRXOKLLURE-UHFFFAOYSA-N 0.000 description 2
- 241001672694 Citrus reticulata Species 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000005657 Fenpyroximate Substances 0.000 description 2
- 241000238631 Hexapoda Species 0.000 description 2
- SECXISVLQFMRJM-UHFFFAOYSA-N N-Methylpyrrolidone Chemical compound CN1CCCC1=O SECXISVLQFMRJM-UHFFFAOYSA-N 0.000 description 2
- 241001454294 Tetranychus Species 0.000 description 2
- 241001454293 Tetranychus urticae Species 0.000 description 2
- YTPLMLYBLZKORZ-UHFFFAOYSA-N Thiophene Chemical compound C=1C=CSC=1 YTPLMLYBLZKORZ-UHFFFAOYSA-N 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 230000002528 anti-freeze Effects 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- YYJNOYZRYGDPNH-MFKUBSTISA-N fenpyroximate Chemical compound C=1C=C(C(=O)OC(C)(C)C)C=CC=1CO/N=C/C=1C(C)=NN(C)C=1OC1=CC=CC=C1 YYJNOYZRYGDPNH-MFKUBSTISA-N 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000000855 fungicidal effect Effects 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 238000003801 milling Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000000447 pesticide residue Substances 0.000 description 2
- 229920001568 phenolic resin Polymers 0.000 description 2
- 239000004576 sand Substances 0.000 description 2
- 239000011265 semifinished product Substances 0.000 description 2
- 231100000820 toxicity test Toxicity 0.000 description 2
- SLYRGJDSFOCAAI-UHFFFAOYSA-N 1,3-thiazolidin-2-one Chemical compound O=C1NCCS1 SLYRGJDSFOCAAI-UHFFFAOYSA-N 0.000 description 1
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 description 1
- 239000005660 Abamectin Substances 0.000 description 1
- 241001580860 Acarapis Species 0.000 description 1
- 241000238876 Acari Species 0.000 description 1
- 241000239290 Araneae Species 0.000 description 1
- 241000123650 Botrytis cinerea Species 0.000 description 1
- 241001643374 Brevipalpus Species 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerol Natural products OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000488585 Panonychus Species 0.000 description 1
- 241001559006 Phyllocoptes Species 0.000 description 1
- 241000497193 Phyllocoptruta Species 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241000233626 Plasmopara Species 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 239000005663 Pyridaben Substances 0.000 description 1
- 241000221662 Sclerotinia Species 0.000 description 1
- 241000317942 Venturia <ichneumonid wasp> Species 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 150000004996 alkyl benzenes Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 150000001448 anilines Chemical class 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000004166 bioassay Methods 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- OOCMUZJPDXYRFD-UHFFFAOYSA-L calcium;2-dodecylbenzenesulfonate Chemical compound [Ca+2].CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O.CCCCCCCCCCCCC1=CC=CC=C1S([O-])(=O)=O OOCMUZJPDXYRFD-UHFFFAOYSA-L 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000000205 computational method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 150000008056 dicarboxyimides Chemical class 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- YKBZOVFACRVRJN-UHFFFAOYSA-N dinotefuran Chemical compound [O-][N+](=O)\N=C(/NC)NCC1CCOC1 YKBZOVFACRVRJN-UHFFFAOYSA-N 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000013401 experimental design Methods 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000012447 hatching Effects 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 231100000194 ovacidal Toxicity 0.000 description 1
- 230000003151 ovacidal effect Effects 0.000 description 1
- 210000004681 ovum Anatomy 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- DWFZBUWUXWZWKD-UHFFFAOYSA-N pyridaben Chemical compound C1=CC(C(C)(C)C)=CC=C1CSC1=C(Cl)C(=O)N(C(C)(C)C)N=C1 DWFZBUWUXWZWKD-UHFFFAOYSA-N 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 229920002545 silicone oil Polymers 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 229930192474 thiophene Natural products 0.000 description 1
- 230000005945 translocation Effects 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 230000037303 wrinkles Effects 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
- A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
- A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention relates to a kind of composition pesticide containing Hexythiazox and fluazinam, active ingredient are made of Hexythiazox and fluazinam, and the weight ratio of Hexythiazox and fluazinam is 1:2-8.Two active constituent synergy of the present invention can delay pest resistance to develop for preventing citrus red mite, reduce the amount of application of each single dose, improve control effect, meet the comprehensive treatment of pest.
Description
Technical field
The present invention relates to a kind of composition pesticides, and in particular to a kind of composition pesticide containing Hexythiazox and fluazinam is used
In the evil mite of prevention agriculturally.
Background technology
Currently, in Agricultural Mites prevention, since evil mite is more from generation to generation, breeding is fast, is also easy to produce resistance, some original preventive effects are very
Good acaricide kind, such as avermectin, pyridaben, by being used for a long time for many years, miticidal effect is decreased obviously or once applies
The time that medicine effectively controls is very short,, generally also can be quickly if not taking resistance precautionary measures even the acaricide newly developed
It develops immunity to drugs.By the use concentration of the access times and raising pesticide of lasting increase pesticide, it is unable to reach ideal anti-
Effect is controlled, cost accounting and environmental pollution are also increased.With the raising of agricultural product production level, more needed in the prevention of evil mite
High-quality and efficient pesticide is selected, with the quality for reducing pesticide residue, improving agricultural product.Based on the above reason, need to continually develop
New acaricide.
Hexythiazox, English are general entitled：Hexythiazox, chemical name：5- (4- chlorphenyls) -3- (N- Cyclohexylaminos
Formyl) the bright base thiazolidine -2 -one of-4- first.It is thiazolidine ketone acaricide, there is preferable penetrability to plant epidermis layer, but
Without uptake and translocation effect.The characteristic that there is strong ovicidal to red spider, kill children mite, to invalid at mite, but to touching medicine
The female of liquid has the function of inhibiting hatching at the produced ovum of mite.
Fluazinam, English name：Fluazinam, chemical name：The chloro- N- of 3- (the chloro- 5- trifluoromethyls -2- pyridyl groups of 3-) -
Fluoro- 2, the 6- dinitros-p-toluidine of α, α, α-three is new substituted phenyl amines, the wide spectrum developed by Japanese Shi Yuan industry companies
Fungicide has special efficacy to a variety of gray molds caused by Botrytis cinerea.Same benzimidazole, dicarboximide class and currently on the market
Existing fungicide no interactions resistance.The germs such as interlink spore genus, Phytophthora, Plasmopara, Sclerotinia and Venturia are drawn
The disease risen also has good activity.Studies have shown that fluazinam has certain systemic activity, there is preferable miticidal effect.
Mixture is carried out using the pesticide of different role mechanism, is the common methods of the agriculture resistant insect of prevention.Pass through pesticide
Recipe determination show that pest control has synergistic function within a certain ratio range between heterogeneity, can effectively improve reality
Border control effect reduces dosage, reduces cost, and can delay pest resistance to insecticide, extend the service life of medicament, be evil mite
The important means of comprehensive treatment.
It is studied by inventor, finds, by the composition of Hexythiazox and fluazinam mixture, have in a certain range well
Synergistic effect, and it is applied to the prevention of red spider there is not yet relevant report in relation to fenpyroximate mixture related to fluazinam.
Invention content
The technical problem to be solved by the invention is to provide a kind of composition pesticide containing Hexythiazox and fluazinam.It is special
Point is higher to plant evil mite activity, has apparent synergistic effect, can obviously reduce the usage amount of single dose pesticide, and composition sheet
Body is not easy to produce resistance.
The technical solution adopted by the present invention is that：A kind of composition pesticide containing Hexythiazox and fluazinam, active ingredient is by thiophene
The weight ratio of mite ketone and fluazinam composition, Hexythiazox and fluazinam is 1:2-8, it is preferred that the weight ratio of Hexythiazox and fluazinam
It is 1:3 or 1:5.
The composition pesticide, the weight percent of Hexythiazox in the composition are 1.5-10%, and fluazinam is combining
Weight percent in object is 4.5-40%.
The composition pesticide presses method known in those skilled in the art, and corresponding adjuvant is added and is configured to fit
Close the practical arbitrary dosage form of agricultural, preferably suspending agent, microemulsion.
The present composition need adjuvant include solvent, emulsifier, wetting agent, stabilizer, antifreezing agent, antifoaming agent,
Thickener, dispersant or it is other be beneficial to active ingredient in the formulation stablize and drug effect play known substance, be all pesticide system
The various composition used is commonly used or allowed in agent field.
Composition pesticide of the present invention, preparation can be used for preventing the evil mite occurred on crops.Evil mite is professional institute
It is well known that evil mite class is damaged to crop or animal, particularly relate to Panonychus citri category (Panonychus spp.), short whisker Acarapis
(Brevipalpus spp.), wrinkle Genus Phyllocoptess (Phyllocoptruta app.), Tetranychus (Tetranychus
spp.).Wherein the composition is especially suitable for effect prevention citrus red mite (crm), Tetranychus urticae.It is especially suitable for prevention and indicates the composition
Preparation is to citrus red mite (crm), Tetranychus urticae activity higher, and dosage is less, and there are unexpected effects.
The invention has the advantages that and remarkable result：
(1) present invention has synergistic function to evil mite, and control effect can be improved, and Pesticide use amount is reduced, to subtract
Small harmful effect and pesticide residue to environment.
(2) two kinds of active ingredient mechanisms of action of the present composition are different, and mixture uses, simultaneous to pest multiple action
Tool, can delay evil mite development of drug resistance, extend the duration of drug effect, while solving single medicament cannot to cover red spider each
The defect of a growth cycle.
Specific implementation mode
Below with measure biocidal activity indoor joint toxicity measuring test and field medicine effect test to the present invention skill
Art scheme and technique effect are described further, and percentage of the present invention is weight percentage.
One, bioassay example
Embodiment 1：The toxicity test of Hexythiazox and fluazinam and different ratio to citrus red mite (crm)
Test method reference《People's Republic of China (PRC) agricultural industry criteria NY/T1154.12-2006》.Pick up from the mandarin orange in field
Jie-Li enzyme-SQ is female at mite, by 30 generation of indoor raising, selects that growth is uniform female to be used as at mite for test worm.Using seedling
Method is connect 120 work of Panonychus citri into mite on small basin citrus seedling, will have the seedling of mite to be sprayed using spray tower, 25 DEG C of immigration,
It cultivates under the conditions of relative humidity 90%, is checked after 15 days, record survival number, meter for statistical analysis with DPS data processing softwares
It calculates regression curve, find out LC50, the increasing of pharmacy mix is evaluated using the co-toxicity coefficient method (CTC) of the nineteen sixties such as Sun Yunpei proposition
Effect acts on.The calculation formula of co-toxicity coefficient is as follows：
Survey toxicity index (ATI)=(standard agent LC50/ reagent agent LC50)×100
In theoretical toxicity index (TTI)=A medicaments ATI × mixture in percentage composition+B medicaments ATI × mixture of A B hundred
Divide content
Co-toxicity coefficient (CTC)=(mixture ATI/ mixture TTI) × 100
When CTC≤80, composition shows as antagonism, and as 80 < CTC < 120, composition shows as summation action,
When CTC >=120, composition shows as synergistic effect.
Test result is shown in Table 1.
The toxicity test (15 days) of 1 Hexythiazox of table, fluazinam and different ratio to citrus red mite (crm)
| Reagent agent | Proportioning | Regression equation (y=a+bx) | Related coefficient | LC50(mg/L) | Co-toxicity coefficient |
| Hexythiazox (A) | / | Y=4.6462+1.3529x | 0.9966 | 1.83 | / |
| Fenpyroximate (B) | / | Y=4.0021+1.4728x | 0.9991 | 4.76 | / |
| A:B | 5:1 | Y=4.3849+1.3526x | 0.9983 | 2.85 | 71.4 |
| A:B | 1:1 | Y=4.4944+1.4263x | 0.9988 | 2.26 | 116.7 |
| A:B | 1:2 | Y=4.4651+1.4548x | 0.9985 | 2.33 | 132.9 |
| A:B | 1:3 | Y=4.5934+1.5507x | 0.9995 | 1.83 | 185.7 |
| A:B | 1:5 | Y=4.5943+1.4398x | 0.9936 | 1.91 | 196.4 |
| A:B | 1:7 | Y=4.4309+1.4772x | 0.9983 | 2.43 | 163.3 |
| A:B | 1:8 | Y=4.3478+1.3138x | 0.9986 | 3.14 | 128.8 |
| A:B | 1:10 | Y=4.3451+1.2025x | 0.9946 | 3.50 | 118.5 |
By table 1 as it can be seen that Hexythiazox and fluazinam in weight ratio are 1:When carrying out mixture between 2-8, poison is each proportioning altogether
Number reaches 120 or more, this shows that composition shows as apparent synergistic effect to the virulence of citrus red mite (crm), when Hexythiazox and
The weight ratio of fluazinam is 1:3,1:5, co-toxicity coefficient is bigger, and synergy is more prominent, this is that have to answer well in field trial
With value.
Two, preparation and Application Example
Embodiment 1：20% Hexythiazox fluazinam suspending agent
Formula：Weigh Hexythiazox 5.0% according to quantity, fluazinam 15%, alkyl phenol formaldehyde resin polyoxyethylene ether 3.6% (point
Powder), alkylphenol-polyethenoxy base ether phosphate 3.2% (wetting agent), polyvinyl alcohol 1.5% (thickener), organosilicon 0.3%
(antifoaming agent), deionized water add to 100% parts by weight.
Embodiment 2：18% Hexythiazox fluazinam suspending agent
Formula：Hexythiazox 3.0%, fluazinam 15.0%, glycerine fatty acid fat acid ester polyoxyethylene ether 2.5% are weighed according to quantity
(dispersant), Negel 3.5% (wetting agent), xanthans 1.5% (thickener), organosilicon 0.2% (antifoaming agent), second
Glycol 2.5% (antifreeze), deionized water add to 100% parts by weight.
Embodiment 3：50% Hexythiazox fluazinam suspending agent
Formula：Hexythiazox 10.0%, fluazinam 40.0%, sodium lignin sulfonate 3.5% (dispersant), 12 are weighed according to quantity
Sodium alkyl sulfate 3.2% (wetting agent), hydroxymethyl cellulose 1.5% (thickener), silicone oil 0.2% (antifoaming agent), ethylene glycol
2.5% (antifreeze), deionized water add to 100% parts by weight.Above-mentioned raw materials are through mixing, and high speed shear disperses 30min, with sand milling
18% Hexythiazox fluazinam suspending agent is made after being sanded in machine.
The preparation method of embodiment 1-3 is：Formula material is weighed according to quantity through mixing, and high speed shear disperses 30min, with sand milling
The suspending agent semi-finished product of the fluazinam containing Hexythiazox are made in machine after being sanded, by packing, casing.
Embodiment 4：6.0% Hexythiazox fluazinam microemulsion
Formula：Hexythiazox 1.5%, fluazinam 4.5%, octyl phenol polyoxyethylene ether 4% (emulsifier), alkyl are weighed according to quantity
Fluosite polyoxyethylene ether 5% (dispersant), calcium dodecyl benzene sulfonate 5% (emulsifier), cyclohexanone 15% (solvent),
N-Methyl pyrrolidone 5% (solvent), 5% n-butanol (emulsifier), epoxychloropropane 1% (stabilizer), through dissolving completely simultaneously
It is uniformly mixed, deionized water adds to 100% parts by weight.
Embodiment 5：12.5% Hexythiazox fluazinam microemulsion
Formula：Hexythiazox 2.5%, fluazinam 10.0% are weighed according to quantity, weigh Hexythiazox 1.5%, fluazinam according to quantity
1.5%, octyl phenol polyoxyethylene ether 4.5% (emulsifier), alkyl phenol formaldehyde resin polyoxyethylene ether 5% (dispersant), 12
Alkyl benzene calcium sulfonate 5.2% (emulsifier), cyclohexanone 15% (solvent), N-Methyl pyrrolidone 5% (solvent), 5% n-butanol
(emulsifier), epoxychloropropane 1.5% (stabilizer), through dissolving completely and being uniformly mixed, deionized water adds to 100% weight
Part.
The preparation method of embodiment 4-5 is：After weighing formula material according to quantity, through dissolving completely and being uniformly mixed, stirring is molten
Solution is added emulsifier, water progress high speed shear, corresponding fluazinam dinotefuran micron-emulsion semi-finished product, packaged dress is made
Case is finished product.
Three, field trial embodiment
Embodiment 1:The preparation (20% Hexythiazox fluazinam suspending agent) of 1 gained of embodiment is prepared for preventing Citrus shatangju
Panonychus citri field trial
(1) experimental design：Experiment is located at Nanning Wuming area doube bridge town, is prevented using spray-on process, with crop leaf
Subject to being sufficiently humidified so as to.Experiment sets 4 processing, including a blank control (CK) altogether, and field insect population, medicine are investigated before dispenser
1 day afterwards, 7 days and 21 days, respectively investigation remain borer population living.Each 3 plants of processing investigation, every plant by the orientation difference of the four corners of the world 4
5 leaves are investigated, is highly located at plant at ground 1/2, looks into 60 leaves altogether, mite number living is recorded, carries out control effect statistics.?
Panonychus citri peak of occurrence dispenser early period, evil mite population quantity in field was 4-15 heads/leaf at that time.Respectively handle corresponding medicament and
Dosage is as follows：
Handle 1#：The preparation of 1 gained of embodiment is prepared, i.e. 20% Hexythiazox fluazinam suspending agent dilutes 3000 times；
Handle 2#：10% hexythiazox micro-emulsion dilutes 1500 times；
Handle 3#：40% fluazinam suspending agent dilutes 2000 times；；
Handle 4#：Blank control (CK)
(2) computational methods are as follows：
In formula:PT0--- before --- -- treatment region medicine；PT1After --- -- treatment region medicine
CK0--- before the medicine of --- -- check plot；CK1After the medicine of --- -- check plot
(3) test result is shown in Table 2
2 20% Hexythiazox fluazinam suspending agent of table prevents the field control effectiveness test statistical form of citrus red mite (crm).
Field trial shows that 20% Hexythiazox fluazinam suspending agent suspending agent has citrus red mite more significant prevention
Effect, 3000 times of control effect are substantially better than 1500 times of 10% hexythiazox micro-emulsion of comparison medicament, the suspension of 40% fluazinam
The control effect that 2000 times of agent, this has obvious synergistic function after illustrating Hexythiazox, fluazinam mixture, improves to mandarin orange
The quick-acting of orange spider and lasting period greatly reduce dosage, experiment section citrus trees growth safety.
In conclusion it is not each component activity that the present invention, which uses 2 kinds of active constituent compound schemes, activity and miticidal effect,
Simple superposition in addition to significant miticidal effect, and have significant synergistic effect compared with existing single formulation,
Quick-acting is high, lasting effect is long, can slow down the generation of red spider resistance, good to crop safety, meets the safety of pesticidal preparations
It is required that.
Claims (4)
1. a kind of composition pesticide containing Hexythiazox and fluazinam, which is characterized in that active ingredient is by Hexythiazox and fluazinam group
At the weight ratio of Hexythiazox and fluazinam is 1:2-8.
2. composition pesticide according to claim 1, which is characterized in that the weight ratio of Hexythiazox and fluazinam is 1:3 or
1:5。
3. composition pesticide according to claim 1, which is characterized in that the weight percent of Hexythiazox in the composition is
1.5-10%, the weight percent of fluazinam in the composition are 4.5-40%.
4. the composition pesticide described in any one claim according to claims 1 to 3 is used to prevent the use of evil mite on plant
On the way.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810700542.8A CN108770861A (en) | 2018-06-29 | 2018-06-29 | A kind of composition pesticide containing Hexythiazox and fluazinam |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810700542.8A CN108770861A (en) | 2018-06-29 | 2018-06-29 | A kind of composition pesticide containing Hexythiazox and fluazinam |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108770861A true CN108770861A (en) | 2018-11-09 |
Family
ID=64030659
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810700542.8A Withdrawn CN108770861A (en) | 2018-06-29 | 2018-06-29 | A kind of composition pesticide containing Hexythiazox and fluazinam |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108770861A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109349274A (en) * | 2018-12-11 | 2019-02-19 | 江阴苏利化学股份有限公司 | A kind of miticide composition containing fluazinam and diafenthiuron |
| CN110100837A (en) * | 2018-12-29 | 2019-08-09 | 京博农化科技有限公司 | A kind of fluazinam and Hexythiazox miticide composition |
-
2018
- 2018-06-29 CN CN201810700542.8A patent/CN108770861A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109349274A (en) * | 2018-12-11 | 2019-02-19 | 江阴苏利化学股份有限公司 | A kind of miticide composition containing fluazinam and diafenthiuron |
| CN110100837A (en) * | 2018-12-29 | 2019-08-09 | 京博农化科技有限公司 | A kind of fluazinam and Hexythiazox miticide composition |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108651524A (en) | The complex preparation and its preparation of a kind of jinggangmeisu and bacillus subtilis and application | |
| CN101642104A (en) | Sterilization composition containing fenoxanil | |
| CN105875594A (en) | Pyraclostrobin, thiamethoxam and carboxin compound suspended seed coating and preparation method thereof | |
| CN108770861A (en) | A kind of composition pesticide containing Hexythiazox and fluazinam | |
| CN101617688A (en) | Pesticide composition containing thiacloprid | |
| CN104824008A (en) | Pesticide composition containing hexythiazox and flufenoxuron | |
| CN107410335A (en) | A kind of bactericidal composition containing thifluzamide and jamaicin | |
| CN108651474A (en) | A kind of miticide composition containing fenpyroximate and fluazinam | |
| CN105104401B (en) | Composition pesticide containing fenpyroximate and flufenoxuron | |
| CN104872164A (en) | Method for preventing citrus red mites | |
| CN104542630A (en) | Antibacterial composition containing zinc thiazole and benziothiazolinone | |
| CN103283731B (en) | Pesticide composition for preventing and treating drug-fast tetranychid mites | |
| CN104957143B (en) | Bactericidal composition containing fluxapyroxad and fludioxonil | |
| CN104705318B (en) | A kind of Pesticidal combination containing rosin acid sodium and spiral shell worm ethyl ester | |
| CN108308190A (en) | The bactericidal composition and application thereof of pyraclostrobin-containing and quinolinone | |
| CN103931621B (en) | A kind of containing Tolfenpyrad with the composition pesticide of cyflumetofen | |
| CN107087627A (en) | A kind of Pesticidal combination containing etoxazole and matrine | |
| CN101622998A (en) | Pesticide composition with synergistic effect | |
| CN101406188B (en) | Acaricide composition with synergism containing spirodiclofen and fenpropathrin | |
| CN103719158B (en) | A kind of composition pesticide preventing and treating crop evil mite | |
| CN104957148A (en) | Bactericidal composition containing fluxapyroxad and zinc thiozole | |
| CN104430434A (en) | Bactericidal composition containing pyraclostrobin and tricyclazole, as well as applications thereof | |
| CN104823985B (en) | A kind of bactericidal composition containing pyridine bacterium azoles and application thereof | |
| CN109362769A (en) | A kind of bactericidal composition containing thiamethoxam, metconazole and dinconazole and application thereof | |
| CN104585179B (en) | A kind of Synergistic mite killing composition containing tebufenpyrad and spirodiclofen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181109 |