CN1085546C

CN1085546C - Medicine for treating coronary heart disease, arteriosclerosis and hypertension

Info

Publication number: CN1085546C
Application number: CN99112189A
Authority: CN
Inventors: 李涛
Original assignee: Individual
Current assignee: Individual
Priority date: 1999-04-29
Filing date: 1999-04-29
Publication date: 2002-05-29
Anticipated expiration: 2019-04-29
Also published as: CN1272379A

Abstract

The invention discloses a medicament and a health product for treating hypertension, arteriosclerosis and coronary heart disease and improving human immunity and a preparation method thereof. The fructus cannabis health-care tea is prepared by taking fructus cannabis, famous cassia seed, scutellaria baicalensis and other Chinese herbal medicines as materials, fully exerting a large amount of amino acids, vitamins and trace elements contained in the fructus cannabis and matching with active ingredients of other Chinese herbal medicines through decoction and extraction. Has obvious curative effect on hypertension, arteriosclerosis and coronary heart disease.

Description

Treatment coronary heart disease, arteriosclerosis, hypertensive medicine

The present invention relates to a kind of treatment coronary heart disease, arteriosclerosis, hypertension, improve the medicine of body immunity.

Urtica cannabina L. belongs to Cannabaceae, contains rich in protein and multivitamin, trace element, aminoacid, folks of china it as a kind of often edible health promoting beverage.In recent years, be that the health food of raw material also is subjected to the parent day by day and hides with the Fructus Cannabis.It is " Bailingkang beverage " of primary raw material with the Fructus Cannabis that Chinese patent CN1116104A discloses a kind of, and with raw material effective component extractings such as Fructus Cannabis, Lentinus Edodes, Semen Cassiae, first meat, preparation has the nutrition oral administration of invigorating the liver and kidney, supporing yang controlling nocturnal emission with astringent drugs, spleen invigorating mind calming; CN1161810A discloses a kind of health beverage and manufacture method made from Fructus Cannabis and oligofructose thereof, and this beverage is used to improve digestive system function, increases effects such as bacillus bifidus.

Purpose of the present invention is exactly the active ingredient that makes full use of in the Fructus Cannabis, cooperates with other Chinese herbal medicine, extracts a kind of treatment coronary heart disease, arteriosclerosis, hypertension, improves the medicine of the medical of body immunity and health care double effects.

The inventor by experiment with clinical observation checking, the Fructus Cannabis needed by human body micronutrient levels of comparing with food oil commonly used is the highest, wherein the content of manganese, ferrum, copper, zinc residence is first.Known manganese is the necessary element of human body, is the activator of plurality of enzymes.Violent and zinc combination is to the facilitation that has of insulin.Manganese also is the essential material of fat enzyme, and blood glucose, blood fat, blood pressure are had positive impact.The WHO tissue thinks that manganese is useful element to cardiovascular, and manganese content and cardiovascular diseases are negative correlation, and cardiovascular is had protective effect.

Solution of the present invention is based on understanding and the Therapeutic Principle of the traditional Chinese medical science to hypertension, arteriosclerosis, coronary heart disease and complication mechanism thereof, achieve with reference to modern pharmacological research, from herbal raw material, filter out natural edible-plant medicines such as Semen Cassiae, Radix Scutellariae, by the theory of Chinese medical science prescription, skim the cream off milk, promoting of the circulation of QI and removing the obstruction in the collaterals, blood circulation promoting and blood stasis dispelling, suppressing the hyperactive liver to relieve the wind syndrome, promote that insulin plays a role, strengthen biological activity, improve blood circulation, blood fat reducing and cholesterol, treatment and alleviation hypertension, arteriosclerosis, Incidence of CHD.

Medicine of the present invention is made up of following raw materials according: (consumption is a weight portion)

The clear and decided sub-8-10 Radix Scutellariae 8-10 of Fructus Cannabis 5-20.

The raw material and the formula optimization proportioning of preparation medicine of the present invention are:

Fructus Cannabis 9-20 Semen Cassiae 8-10 Radix Scutellariae 8-10

Rhizoma Alismatis 10-12 Rhizoma Chuanxiong 8-10 Radix Salviae Miltiorrhizae 10-12.

According to above-mentioned prescription it is decocted, separate moisture, preparation soft gelatin capsule or oral liquid.

The inventor carries out a large amount of clinical trial certificates with above-mentioned oral liquid, and Chinese medicine batching of the present invention is reasonable, and clinical practice is evident in efficacy.Effective percentage reaches 96.8%, and obvious effective rate reaches 78.5%, and inefficiency only is 3.2%.To middle-aged and elderly people coronary heart disease, hypertension, especially triglyceride, cholesterol are higher, with have a dizzy spell, the middle-older patient of constipation, it is more obvious than other medicines effect to take the back.

The case alternative condition:

1, the age is more than 40 years old.

2, electrocardiogram has hat for not enough performance.

3, blood pressure surpasses this age group normal value (based on systolic pressure).

4, blood fat is higher than normal value (one of two of triglycerides, cholesterol or two all be higher than normal value).

5, the optical fundus performance has the arteriosclerosis performance.

6, subsidiary conditions: sensation of oppression over the chest with shortness of breath, chronic constipation.

Wherein first is essential condition, and the 2-5 item possesses can selecting for use of one of them.

Efficacy determination: medication 30th was a course of treatment, and the produce effects that is of the above obviously improvement of binomial is arranged in the 2-5 item; There is one to be improved as effectively or to take two more than the course of treatment, has two to be improved as effectively in the 2-5 item; Take two courses of treatment, more than every all do not have be improved as invalid.

Enumerate two typical cases below and cure case:

(1), Lee * *, woman, 48 years old, Han nationality, people from Jining City, Shandong, office work.

First visit: on March 20th, 1998.

Private prosecution: ambition, the ictal pain of pareordia, the companion takes on, carries on the back acid and dull pain, general weakness, half a year is many.There is habitual constipation for many years.Hospital is diagnosed as coronary heart disease at this city, takes medicine to alleviate for the moment often outbreak, nervous, the vexed pain in ambition.

Have a medical check-up: BP 182/106mmHg, apex beat strengthens, A ₂＞P ₂, the optical fundus tremulous pulse is the filamentary silver shape, and arteriovenous intersection impression is arranged.Dimly red tongue, there is ecchymosis on the tongue limit, and the greasy arteries and veins of the little Huang of tongue fur is dazzled carefully.

Laboratory examination: triglyceride 2.8mmol/L

Cholesterol 9.2mmol/L

Electrocardioscopy: the S-T elongated segment, move down, the T ripple is low flat.

Diagnosis: hypertension II phase, arteriosclerosis, coronary disease disease.

The rule of treatment: promoting of the circulation of QI and removing the obstruction in the collaterals, activating blood circulation to dissipate blood stasis, the multiple arteries and veins of enriching blood, loosening bowel to relieve constipation.

Side's medicine: obey oral medicine liquid of the present invention, every day three times, each 20 milliliters, taking 30 continuously is a course of treatment.

Further consultation: on April 21st, 1998.

Private prosecution: the first visit symptom is obviously alleviated or is disappeared, no constipation.

Have a medical check-up: BP 160/96mmHg, cardiac auscultation takes a turn for the better, and examination of ocular fundus obviously improves.

The laboratory is checked: triglyceride 2.0mmol/L

Cholesterol 8.2mmol/L

Electrocardioscopy: the S-T section moves down slightly, and the T ripple is normal substantially.

The rule of treatment: continued to take this oral liquid 30.

3 examine: on May 22nd, 1998.

Private prosecution: the first visit transference cure, it is unimpeded to defecate, and every day 1-2 time, whole body is brisk pleasant, strong.

Have a medical check-up: BP 140/88mmHg.Cardiac auscultation is normal, and the examination of ocular fundus sign disappears.

The laboratory is checked: triglyceride 1.8mmol/L

It is normal that cholesterol 6.9mmol/L recovers

Electrocardioscopy: electrocardiogram is normal.

(2), Liu * *, man, 52 years old, Han nationality, people from Weihai City, Shandong, cook.

First visit: on April 8th, 1998.

Private prosecution: the vexed pain in ambition is more than 1 year, dizzy sometimes, numbness of hand, general weakness.Be diagnosed as coronary heart disease, hypertension in this city hospital.During sick sending out, informal dress can be alleviated with SUXIAO JIUXIN WAN temporarily, but can not drug withdrawal.

Have a medical check-up: BP 183/110mmHg, border of cardiac dullness enlarges, arrhythmia.

The laboratory is checked: triglyceride 2.7mmol/L

Cholesterol 9.0mmol/L

Electrocardiogram: S-T section obviously prolongation moves down, and the T ripple is low flat.

Diagnosis: hypertension, coronary heart disease.

The rule of treatment: benefiting QI and nourishing blood, blood circulation promoting and blood stasis dispelling, collateral dredging is dredged breast, suppressing the hyperactive liver to relieve the wind syndrome.

Side's medicine: take medicine oral liquid of the present invention, every day three times, each 20ml took 30 continuously.

Further consultation: on May 20th, 1998.

Private prosecution: the vexed alleviation of pain in ambition is light, and is not dizzy, and whole body is strong.

Have a medical check-up: the BP 170/105mmHg rhythm of the heart is clearly better, and heart circle dwindles, and it is normal that the tongue arteries and veins all becomes.

The laboratory is checked: triglyceride 2.1mmol/L

Cholesterol 8.0mmol/L

Electrocardiogram: the S-T section moves down slightly, and the T ripple is near normal.

The rule of treatment: continued to take the top 30.

3 examine: on May 22nd, 1998.

Private prosecution: whole body brisk pleasant, walking is strong, does not have dizzy.

Have a medical check-up: BP 135/890mmHg, the rhythm of the heart is regular, and the tongue arteries and veins is all normal.

The laboratory is checked: triglyceride 1.78 mmol/L

Cholesterol 7.0mmol/L

Electrocardioscopy: electrocardiogram is normal.

Patient obeyed the top 30 voluntarily again.

Embodiment:

Take by weighing raw material (kilogram) by following proportioning:

Fructus Cannabis 9-20 Semen Cassiae 8-10 Radix Scutellariae 8-10

Preparation method is as follows:

Six kinds of raw materials are mixed to put in the 300-540 intensification water soaked 2 hours, decocted 1 hour with low baking temperature then, take out decocting liquid, add water then and decocted successively twice 30 minutes for 100 liters.Respectively get the decocting liquid filtration that is mixed for three times, altogether 100 liters of decocting liquids.Cooling, fill at last, 20 milliliters every bottle, the oral liquid finished product is made in packing, check.

Claims

1, a kind of treatment coronary heart disease, arteriosclerosis, hypertensive medicine is characterized in that it is the medicament of being made by following materials of weight proportions: Fructus Cannabis 5-20 Semen Cassiae 8-10 Radix Scutellariae 8-10.

2, treatment coronary heart disease according to claim 1, arteriosclerosis, hypertensive medicine is characterized in that its raw material and proportioning are: Fructus Cannabis 9-20 Semen Cassiae 8-10 Radix Scutellariae 8-10 Rhizoma Alismatis 10-12 Rhizoma Chuanxiong 8-10 Radix Salviae Miltiorrhizae 10-12.

3, treatment coronary heart disease according to claim 1 and 2, arteriosclerosis, hypertensive medicine is characterized in that said medicament is the said dosage form of any pharmaceutics.

4, treatment coronary heart disease according to claim 3, arteriosclerosis, hypertensive medicine is characterized in that said medicament is a kind of liquid preparation.

5, treatment coronary heart disease according to claim 4, arteriosclerosis, hypertensive medicine, it is characterized in that this liquid preparation can with all kinds of fruit juice, milk, coffee, glucose, and other liquid beverage mix, make the auxotype oral liquid.