CN103550480B - Chinese herbal preparation for treating coronary heart disease complicated with hypertension - Google Patents
Chinese herbal preparation for treating coronary heart disease complicated with hypertension Download PDFInfo
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- CN103550480B CN103550480B CN201310567272.5A CN201310567272A CN103550480B CN 103550480 B CN103550480 B CN 103550480B CN 201310567272 A CN201310567272 A CN 201310567272A CN 103550480 B CN103550480 B CN 103550480B
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Abstract
The invention discloses a Chinese herbal preparation for treating coronary heart disease complicated with hypertension. In modern medicine, most of the coronary heart diseases belong to thoracic obstruction domain of the traditional Chinese medicine. According to the traditional Chinese medicine differentiation, the patient of coronary heart disease complicated with hypertension has common symptoms of yin deficiency, yang excess, blood stasis and obstruction, and the pathogenesis lies in deficiency in origin and enrichment in symptom. The Chinese herbal preparation disclosed by the invention is a decoction prepared by decocting traditional Chinese medicines such as foldleaf daylily root, caragana microphylla, Chinese holly bark, the root of cynanchum inamoenum, bornet cowlily rhizome, the root of dalbergia hupeana, prunus japonica, black mountain ebony, love-lies-bleeding root, daphne odera, hairy clover shrub and ventilago leiocarpa benth which have the effects of nourishing the liver and kidney, calming the liver, suppressing yang, managing qi and promoting blood circulation in water. Clinical tests prove that the total effective rate is as high as 97.5% and no evident adverse reaction is caused to the patients during treatment.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine preparation for the treatment of coronary heart disease with hypertension.
Background technology
Along with the development of society and the improvement of living condition, the sickness rate of coronary heart disease is in rising trend, hypertension is the important risk factor of coronary heart disease, for the patient of coronary heart disease with hypertension, Comprehensive Treatment is preferred plan, and the medicine therefore developing the Comprehensive Treatment primary disease that curative effect is high, side effect is little has important practical significance.Current treatment with western coronary heart disease with hypertension is that separately treatment two is sick, exist take medicine that incidence rate that is of a great variety, side effect increases, Long-term taking medicine costly, the weak point such as patient compliance difference.The Chinese medicine compound of Chinese medicine possesses the advantage of multicomponent, Mutiple Targets, multipath disease therapy, side's multiple-effect, convenient and safe, treating both the principal and secondary aspects of a disease, for clinical treatment coronary heart disease with hypertension provides a kind of new thinking.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of coronary heart disease with hypertension.The coronary heart disease of modern medicine belongs to Chinese medicine thoracic obstruction category more, in long-term clinical practice, we observe the patient of coronary heart disease with hypertension, Chinese medical discrimination hinders for common pattern of syndrome with hyperactivity of YANG due to deficiency of YIN, Yu Xue Bi, pathogenesis belongs to deficiency in origin and excess in superficiality, act on the principle of the traditional Chinese medical science " organic conception, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs ", treating different diseases with the same therapeutic principle, we establish the Therapeutic Principle of nourishing the liver and kidney, suppressing the hyperactive liver and subsiding YANG, vital energy regualting and blood circulation-promoting.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment coronary heart disease with hypertension is made up of the Chinese medicine of following weight portion: Radix hemerocalis plicatae 9-15 part, Herba Caraganae intermediae 20-25 part, Cortex Ilicis Cornutae 25-30 part, Radix Tylophorae arenicolae 9-15 part, Rhizoma Nupharis Bornetii 30-60 part, Caulis Dalbergiae Hancei 6-9 part, Radix Pruni Japonicae 7-10 part, Radix Bauhiniae Lecomtei 9-15 part, Radix Amaranthi Caudati 10-30 part, Radix Buddlejae Butterflybush 14-16 part, Radix Campylotropis hirtellae 30-50 part, Caulis seu Radix Schisandrae Henryi 15-25 part.
Preferred: Radix hemerocalis plicatae 12 parts, Herba Caraganae intermediae 23 parts, Cortex Ilicis Cornutae 28 parts, Radix Tylophorae arenicolae 12 parts, Rhizoma Nupharis Bornetii 45 parts, Caulis Dalbergiae Hancei 7 parts, Radix Pruni Japonicae 8.5 parts, Radix Bauhiniae Lecomtei 12 parts, Radix Amaranthi Caudati 20 parts, Radix Buddlejae Butterflybush 15 parts, Radix Campylotropis hirtellae 40 parts, Caulis seu Radix Schisandrae Henryi 20 parts.
Above-mentioned Chinese medicine decocting is made decoction by preparation method.
Fang Zhong: Radix hemerocalis plicatae is nourished blood suppressing the hyperactive liver, inducing diuresis to remove edema; Herba Caraganae intermediae nourishing the blood and yin; Cortex Ilicis Cornutae nourishing YIN, liver and kidney tonifying; Radix Tylophorae arenicolae enriching yin and nourishing kidney, invigorating the spleen and benefiting QI, spleen invigorating heart tonifying; Rhizoma Nupharis Bornetii nourishing YIN and clearing away heat; Caulis Dalbergiae Hancei promoting the circulation of QI to relieve pain; Radix Pruni Japonicae thin stagnant, removing food stagnancy of regulating the flow of vital energy gathers; Radix Bauhiniae Lecomtei regulating QI to relieve pain, reduce phlegm diuretic; Radix Amaranthi Caudati strengthening by means of tonics; Radix Buddlejae Butterflybush blood circulation promoting and blood stasis dispelling; Radix Campylotropis hirtellae promoting blood flow to regulate menstruation, regulating QI to relieve pain; Caulis seu Radix Schisandrae Henryi detumescence is nourished blood, regulating QI to expel dampness.
Detailed description of the invention
Embodiment one: take Radix hemerocalis plicatae 12g, Herba Caraganae intermediae 23g, Cortex Ilicis Cornutae 28g, Radix Tylophorae arenicolae 12g, Rhizoma Nupharis Bornetii 45g, Caulis Dalbergiae Hancei 7g, Radix Pruni Japonicae 8.5g, Radix Bauhiniae Lecomtei 12g, Radix Amaranthi Caudati 20g, Radix Buddlejae Butterflybush 15g, Radix Campylotropis hirtellae 40g, Caulis seu Radix Schisandrae Henryi 20g.Above-mentioned Chinese medicine decocting is become decoction.
Embodiment two: take Radix hemerocalis plicatae 15g, Herba Caraganae intermediae 25g, Cortex Ilicis Cornutae 25g, Radix Tylophorae arenicolae 9g, Rhizoma Nupharis Bornetii 60g, Caulis Dalbergiae Hancei 6g, Radix Pruni Japonicae 10g, Radix Bauhiniae Lecomtei 9g, Radix Amaranthi Caudati 30g, Radix Buddlejae Butterflybush 16g, Radix Campylotropis hirtellae 50g, Caulis seu Radix Schisandrae Henryi 15g.Above-mentioned Chinese medicine decocting is become decoction.
Embodiment three: take Radix hemerocalis plicatae 9g, Herba Caraganae intermediae 20g, Cortex Ilicis Cornutae 30g, Radix Tylophorae arenicolae 15g, Rhizoma Nupharis Bornetii 30g, Caulis Dalbergiae Hancei 9g, Radix Pruni Japonicae 7g, Radix Bauhiniae Lecomtei 15g, Radix Amaranthi Caudati 10g, Radix Buddlejae Butterflybush 14g, Radix Campylotropis hirtellae 30g, Caulis seu Radix Schisandrae Henryi 25g.Above-mentioned Chinese medicine decocting is become decoction.
Clinical data
1. the 80 routine coronary heart disease with hypertension patients that my institute of physical data random selecting year January in January, 2008 to 2011 is to our hospital, wherein man 51 example, female 29 example; 40 ~ 79 years old age; The course of disease is the longest 19 years, the shortest 5 months.Clinical hypertension, diagnostic criteria for coronary heart disease are all met to all patient diagnosis inspections.
2. diagnostic criteria diagnosis of coronary heart disease foundation WHO in 1980 is about diagnostic criteria for coronary heart disease.Diagnosing Hypertension is according to nineteen ninety WHO/ISH blood pressure level and defining classification.
3. this group of Therapeutic Method patient takes Chinese medicine preparation of the present invention, takes Radix hemerocalis plicatae 12g, Herba Caraganae intermediae 23g, Cortex Ilicis Cornutae 28g, Radix Tylophorae arenicolae 12g, Rhizoma Nupharis Bornetii 45g, Caulis Dalbergiae Hancei 7g, Radix Pruni Japonicae 8.5g, Radix Bauhiniae Lecomtei 12g, Radix Amaranthi Caudati 20g, Radix Buddlejae Butterflybush 15g, Radix Campylotropis hirtellae 40g, Caulis seu Radix Schisandrae Henryi 20g.Decocting makes decoction.Every day 2 times, each 200ml 8 weeks was 1 course for the treatment of.If treatments period angina pectoris attacks, can buccal nitroglycerin temporarily.Period in a medicine advises patient's wine for giving off smoking, avoids pungent food, and diet is light, smooth feelings will, untired.
4. criterion of therapeutical effect coronary heart disease and angina pectoris (thoracic obstruction) the standard of curative effect evaluation: according to 1993 Ministry of Health of the People's Republic of China " new Chinese medicine guideline of clinical investigations " draft.Effective: after the treatment carrying out oral drugs, effectively reduce blood pressure to normal scope, coronary heart disease symptom obtains good improvement.Effective: can to reduce blood pressure significantly, but do not reach in normal range, more higher than normal arterial pressure scope, but relatively steadily can control, coronary heart disease symptom and sign are obviously improved.Invalid: blood pressure does not significantly reduce or raises gradually on the contrary, and it is more unstable that blood pressure detecting obtains data, and be difficult to control, coronary heart disease symptom and sign have no remarkable alleviation, the even performance that increases the weight of of Progressive symmetric erythrokeratodermia.
5. observe the curative effect, wherein effective 58 examples (72.5%) after the course for the treatment of of this group of therapeutic effect patient treatment, effective 20 examples (25.0%), invalid 2 examples (2.5%), total effective rate 97.5%.Treatments period patient has no obvious adverse reaction.
Claims (2)
1. treat a Chinese medicine preparation for coronary heart disease with hypertension, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Radix hemerocalis plicatae 9-15 part, Herba Caraganae intermediae 20-25 part, Cortex Ilicis Cornutae 25-30 part, Radix Tylophorae arenicolae 9-15 part, Rhizoma Nupharis Bornetii 30-60 part, Caulis Dalbergiae Hancei 6-9 part, Radix Pruni Japonicae 7-10 part, Radix Bauhiniae Lecomtei 9-15 part, Radix Amaranthi Caudati 10-30 part, Radix Buddlejae Butterflybush 14-16 part, Radix Campylotropis hirtellae 30-50 part, Caulis seu Radix Schisandrae Henryi 15-25 part.
2. a kind of Chinese medicine preparation for the treatment of coronary heart disease with hypertension according to claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Radix hemerocalis plicatae 12 parts, Herba Caraganae intermediae 23 parts, Cortex Ilicis Cornutae 28 parts, Radix Tylophorae arenicolae 12 parts, Rhizoma Nupharis Bornetii 45 parts, Caulis Dalbergiae Hancei 7 parts, Radix Pruni Japonicae 8.5 parts, Radix Bauhiniae Lecomtei 12 parts, Radix Amaranthi Caudati 20 parts, Radix Buddlejae Butterflybush 15 parts, Radix Campylotropis hirtellae 40 parts, Caulis seu Radix Schisandrae Henryi 20 parts.
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| CN105998756A (en) * | 2016-07-26 | 2016-10-12 | 王晨 | Medicament for treating hypertension and coronary heart disease and preparation method of medicament |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1272379A (en) * | 1999-04-29 | 2000-11-08 | 李涛 | Medicine for treating coronary heart disease, arteriosclerosis and hypertension |
| CN1382463A (en) * | 2001-04-20 | 2002-12-04 | 徐忠廷 | Chinese-medicinal capsule for treating cardiovascular and cerebrovascular diseases |
| CN101468188A (en) * | 2007-12-27 | 2009-07-01 | 吴伶 | Health-care medicament for treating hypertension |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1272379A (en) * | 1999-04-29 | 2000-11-08 | 李涛 | Medicine for treating coronary heart disease, arteriosclerosis and hypertension |
| CN1382463A (en) * | 2001-04-20 | 2002-12-04 | 徐忠廷 | Chinese-medicinal capsule for treating cardiovascular and cerebrovascular diseases |
| CN101468188A (en) * | 2007-12-27 | 2009-07-01 | 吴伶 | Health-care medicament for treating hypertension |
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