CN108354880A - A kind of baby child's skin care compositions and methods - Google Patents
A kind of baby child's skin care compositions and methods Download PDFInfo
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- CN108354880A CN108354880A CN201810337851.3A CN201810337851A CN108354880A CN 108354880 A CN108354880 A CN 108354880A CN 201810337851 A CN201810337851 A CN 201810337851A CN 108354880 A CN108354880 A CN 108354880A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/736—Chitin; Chitosan; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
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Abstract
The invention discloses a kind of baby child's skin care compositions and methods, the skin care compositions and methods are by following mass percent at being grouped as：Poly hexamethylene biguanide 0.001 ~ 0.3%；Chitosan 0.0005 ~ 1.0%；Camellia flower extract 0.0005 ~ 0.5%；Aloe extract 0.0005 ~ 0.5%；Grape fruit extract 0.0005 ~ 0.5%；Violet cabbage extract 0.0005 ~ 0.5%.The beneficial effects of the invention are as follows：Compound prescription is used, pure plant extracts are used as host agent quick potent killing bacterium, virus using poly hexamethylene biguanide, chitosan：Camellia flower extract, aloe extract, grape fruit extract, violet cabbage extract.Complex treatment solves the skin problem of infant's nongenetic.Product does not have any irritation, while sterilizing and itch-relieving, additionally it is possible to nourishes rough skin.
Description
Technical field
The invention belongs to traditional Chinese medicine health technology fields, more particularly to a kind of baby child's skin care compositions and methods.
Background technology
Skin is the maximum organ of human body, it is covered in body surface, on the one hand prevents moisture, electrolyte and nutriment
Loss, on the other hand prevent harmful substance, pathogenic microorganism invasion.Infant's skin has the physiology different from adult special
Point, structure, ingredient and function are all dramatically different with adult.It is generally acknowledged that the function of skin is developed in gestational age 32~34 weeks
It is ripe, and when by 8~24 months, skin barrier function is just finally reached adult levels.Infant's skin is thin compared with adult's cuticula,
Horn cell is small, and the hydratability of skin is still not perfect, and more moisture and less natural moisturizing factor are contained in cuticula
Deng these features make infant be more prone to various skin problems.
Particularly, the skin of infant top layer is made of unicellular cuticula, is contained a small amount of fiber, is lacked elasticity,
Thickness is only adult 1/10, and subcutaneous fat is few, is easy to be lost in moisture, skin typically exhibits out relatively dry state.Baby children
Youngster's skin is easily injured by extraneous penetration toxic or excitatory, and does not resist dry ability, decortication, cracking
Phenomenon occurs often.Skin development degree is low so that the immune system of infant is weak, and the energy of bacterial virus is resisted without adult
Power, skin are easy to suffer bacterial invasion, the allergic symptoms such as erythema, erythema, bubble occur.Infant's common skin problem is introduced such as
Under：
Eczema is a kind of common allergic inflammation dermatoses, is dermatology common disease, frequently-occurring disease, and feature is polymorphism
Fash has exudation, symmetrical, is easy to recurrence and chronicity, feels itching, and severe patient, inflammation is apparent, moistening, erosion, can be general
Whole body is sent out, if treatment is not in time or malpractice, protracted course can be caused, great inconvenience is caused to the living and studying of infant.
Diaper rash is the frequently-occurring disease of infant, common disease, and the overwhelming majority is to the enzyme in moist, friction, urine and excrement
The primary irritant of generation reacts, and shows as that skin heart is congested, rubescent, swelling, may occur in which diffusate, routed after supervention
Ulcer, with erythema and papule, often companion infects in several cases.
Seborrhea:Seborrhea, including the damage of scalp, face, ears, front sheet erythema are shown as, it is greasy
Yellow crusts, it is symmetrical.
Grain shape papule：The typically tip-like white papule of very little, is common in nose, cheek, forehead etc..
Atopic dermatitis：A kind of chronic inflammatory skin, be often apt to occur in face, mouth week, four limbs, feature be erythema,
Papule has sepage, skin usually to dry after scratching, since chronic scratching can form lichenification and pigmentation.
Invention content
The present invention provides a kind of baby child's skin care compositions and methods safely, effectively, non-stimulated.
To achieve the above object, the present invention uses following technical proposals：A kind of baby child's skin care compositions and methods, the skin
Care composition is by following mass percent at being grouped as：
As an optimization, the skin care compositions and methods by following mass percent at being grouped as：
As an optimization, the skin care compositions and methods by following mass percent at being grouped as：
A kind of preparation method of baby child's skin care compositions and methods, comprises the following steps that：
(1) poly hexamethylene biguanide is added in the container for filling deionized water, stirs evenly, stands overnight；
(2) chitosan is added in the aqueous solution that is obtained to step (1), stirring makes it be uniformly mixed；
(3) camellia flower extract is added in the aqueous solution that is obtained to step (2), stirring makes it be uniformly mixed；
(4) aloe extract is added in the aqueous solution that is obtained to step (3), stirring makes it be uniformly mixed；
(5) grape fruit extract is added in the aqueous solution that is obtained to step (4), stirring makes it be uniformly mixed；
(6) violet cabbage extract is added in the aqueous solution that is obtained to step (5), stirring makes it be uniformly mixed, produced
Object.
As an optimization, mixing time is 30~90min in the step (2), (3), (4), (5), (6).
Wherein：
Polyhexamethylene guanide:Environment-friendly type macromolecule polymer disinfection sanitizer, with broad-spectrum, effective concentration is low, makees
With the excellent performance that speed is fast, property is stable, soluble easily in water；It can use at normal temperatures, is long-term antibacterial, without side-effects, corrosion-free
It is property, colourless, odorless, nontoxic, non-ignitable, not quick-fried, safe to use.Polyguanidine family macromolecule polymer, can generate ionization in aqueous solution,
Strong electropositive is contained in its hydrophilic group part, and absorption is usually in electronegative all kinds of bacteriums, virus, into cell membrane, suppression
It is film-made the synthesis of lactones plastid, thalline apoptosis is caused, reaches best bactericidal effect.
Chitosan：Chitosan (chitosan) is also known as chitosan, is the chitin being widely present by nature
(chitin) pass through what deacetylation obtained, chemical name is Chitosan (1-4) -2- amino-B-D glucose.From
1859, after Frenchman Rouget obtains chitosan first, the biological functionality and compatibility of this natural polymer, blood phase
The excellent performances such as capacitive, safety, microbic resolvability are obtained by all trades and professions extensive concern in the application study of numerous areas
Major progress.Chitosan and its derivative has preferable antibacterial activity, and the growth of some fungies, bacterium and virus can be inhibited numerous
It grows, Antibacterial Mechanism can be summarized as following aspects：First, due to the polycation of chitosan, it is easy to fungal cell surface
Negatively charged group effect, to change the mobility and permeability of pathogen cell membrane；Second is that interfering the duplication of DNA and turning
Record；Third, blocking pathogen metabolism.
Camellia is Theaceae Camellia Plants, is commonly called as Datura tree, shallow lake overgrown with wild plants spring, mountain Chinese toon, resistance to winter, camellia, late camellia, tea
Flower, foreign tea, it not only has ornamental value also to be had broad application prospects in food, medicine and other field.Camellia extracts
Object mainly contains the chemical compositions such as flavonoids, triterpenes, organic acid, saponin(e, tannin, and there is convergence cool blood, hemostasis, external application to control burning
Scald, traumatic bleeding.
Aloe is liliaceous plant, is rich in various trace elements, amino acid, vitamin, glycoside and phenols isoreactivity substance,
It is widely used as the antioxidant of foods and cosmetics.Aloe bactericidal antiphlogistic and beauty functions protrude, and sterilizing function is better than anti-
Raw element, can directly sterilize, drug resistance is not generated to bacterium, antibiotic resistance bacterium can be effectively killed, due to containing grape in aloe
Sugar, mannose, uronic acid, calcium, hydrated protein enzyme, bio-hormone, hormone, protein, amino acid, vitamin, minerals with
And other trace elements, therefore with nourishing and moisturizing, sun-proof, Hang Yan, hair-dressing and hair care and other effects, meanwhile, it is to softening skin, receipts
It holds back, prevents acne, prevent pachylosis, anti-inflammatory anti-itch, hair care, keep skin delicacy is clean etc. in vain to have remarkable efficacy.Aloe has
Good compatibility can coordinate well with various cosmetic materials, and can eliminate injury of a variety of surfactants to skin.
It is specific as follows：(1) the anthracene ketone compounds in sterilization and anti-inflammatory effect aloe have sterilization, antibacterial, anti-inflammatory, removing toxic substances, rush mostly
Into the effects that wound healing.(2) beauty functions aloe contains aloin, Aloesin have the effect of many-sided beautifying skin
Can, it has certain effect in moisturizing, anti-inflammatory, antibacterial, antipruritic, antiallergy, softening skin, anti-acne, antiperspirant deodorization etc. tool,
There is strong absorption to ultraviolet light, prevents skin burn.Aloe eliminates the ingredient of superoxide radical containing there are many, such as
Superoxide dismutase, catalase can make skin delicate, flexible, have the effects that anti-corrosion.Aloe Vera Gel is natural sun-prevention
Ingredient can effectively inhibit the ultraviolet light in daylight, prevent pigmentation, keep whitening skin.The study found that aloe, which has, makes skin
Skin convergence, moisturizing, anti-inflammatory, releases hardening, angling, improves the effects that scar softness.
Grape fruit extract is a kind of commercialized plant extracts, is proposed from grape fruit seed and pulp, is changed
Scientific name claims to be compound xenol hydroxy benzenes, is a kind of very potential high-efficiency broad spectrum bacteriostatic compound, just in extremely low concentration
Apparent bactericidal effect can be obtained, totally nontoxic is without side-effects to beneficial microbe, anti-without any stimulation or allergy to human body
It answers.Grape fruit extract has the function of anti-inflammatory and antalgic, antiviral, antibacterial and inhibition eye aldose reductase, being capable of nurse tissue
Cell, antibacterial anti-infection.
Violet cabbage also known as red cabbage, purple cabbage or purple cabbage are rich in multivitamin and mineral element, sulphur member therein
Element can desinsection it is antipruritic, for various pruituses, the illness such as eczema have certain curative effect.Violet cabbage also contains anthocyanidin and dimension
Raw element C has the function of anti-oxidant and inhibits pathogenic microorganism.
The beneficial effects of the invention are as follows：Compound prescription is used, it is quickly strong as host agent using poly hexamethylene biguanide, chitosan
Effect kills bacterium, virus, while using pure plant extracts：Camellia flower extract, aloe extract, grape fruit extract, purple
Cabbage extract.Complex treatment solves the skin problem of infant's nongenetic.Product does not have any irritation, stops in sterilization
While itching, additionally it is possible to nourishes rough skin.
Curative effect of the present invention includes mainly：Prevent hand-foot-and-mouth disease；The small hip of baby are wiped, diaper rash can be prevented.Because wound,
The reparation of skin injury caused by burn and scald and skin, which are kept a public place clean, waits daily nursings；The antibacterial cleaning of umbilical region of ewborn infant；Summer body
There are red and swollen, the symptoms such as pain of itching in body prickly heat after bite by mosquitos, on skin；Ewborn infant and childhood eczema, impetigo neonatorum,
Papular urticaria etc. is for infant's skin, the sterilizing of mucous membrane and private parts；Killing cause mucocutaneous redness, itch,
Rotten to the corn, the symptoms such as fester, suppurate germs.
Specific implementation mode
The following is a clear and complete description of the technical scheme in the embodiments of the invention, it is clear that described embodiment
Only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field
The every other embodiment that art personnel are obtained without creative efforts belongs to the model that the present invention protects
It encloses.
Embodiment 1
A kind of baby child's skin care compositions and methods, the skin care compositions and methods are by following mass percent at being grouped as：
In said components, poly hexamethylene biguanide is added in the container for filling deionized water, stirs evenly, placed
Night；Chitosan is sequentially added into above-mentioned aqueous solution, stirs 60min, it is made to be sufficiently mixed uniformly；Then at interval of 60min, first
Camellia flower extract, aloe extract, grape fruit extract, violet cabbage extract is added in backward container, stirs
Obtain final finished.
Embodiment 2
A kind of baby child's skin care compositions and methods, the skin care compositions and methods are by following mass percent at being grouped as：
In said components, poly hexamethylene biguanide is added in the container for filling deionized water, stirs evenly, placed
Night；Chitosan is sequentially added into above-mentioned aqueous solution, stirs 30min, it is made to be sufficiently mixed uniformly；Then at interval of 30min, first
Camellia flower extract, aloe extract, grape fruit extract, violet cabbage extract is added in backward container, stirs
Obtain final finished.
Embodiment 3
A kind of baby child's skin care compositions and methods, the skin care compositions and methods are by following mass percent at being grouped as：
In said components, poly hexamethylene biguanide is added in the container for filling deionized water, stirs evenly, placed
Night；Chitosan is sequentially added into above-mentioned aqueous solution, stirs 90min, it is made to be sufficiently mixed uniformly；Then at interval of 90min, first
Camellia flower extract, aloe extract, grape fruit extract, violet cabbage extract is added in backward container, stirs
Obtain final finished.
Final finished obtained is colourless liquid in Examples 1 to 3.
By Examples 1 to 3 products obtained therefrom number consecutively A1-A3, to total number of bacterial colonies, fungus colony sum, coliform
Group, Pseudomonas aeruginosa, hemolytic streptococcus and staphylococcus aureus index are detected, and experiment proves to meet《Disinfection technology
Specification》(version in 2002) provides.
1 microbial contamination testing result of table
By Examples 1 to 3 products obtained therefrom foundation《Disinfection technology standard》(version in 2002) carries out bacteriostasis property identification, will be golden
Staphylococcus aureus (ATCC6538) culture to the 6th generation, Escherichia coli (8099) are cultivated to the 6th generation, Candida albicans
(ATCC10231) culture is provided to the 6th generation by Shandong Center for Disease Control ＆ Prevention, this experiment uses pressuresteam sterilization
Nutrient agar tested at 19~21 DEG C.
By Examples 1 to 3 products obtained therefrom foundation《Disinfection technology standard》(version in 2002) carries out multiple intact skin stimulation
Experiment chooses Jinan Xi Lingjiao and cultivates Breeding Center (production licence number：SCXK (Shandong) 20150001) provide regular grade it is new
Western blue rabbit 3.Experimental condition：Experimental Animal Center barrier environment animal housing of Shandong Province, uses credit number：SYXK (Shandong)
20140010,20~25 DEG C of temperature, relative humidity 50~70%.Rabbit feed is by Beijing HFK Bio-Technology Co., Ltd.
It provides, production licence number：SCXK (capital) 20140008.
The day before yesterday is tested, experiment rabbit back backbone both sides hair is cut, the left and right each about 3cm × 3cm of unhairing range.Using
Self-control method is tested, and 0.5ml given the test agent is taken, and is coated on the skin that right side is exposed, the conduct pair of left side exposed skin
According to.After every experimental rabbit smears 4h, the skin for smearing position is cleaned with warm water, removes residue, and smearing is primary daily, continuous to apply
Smear 14d.Observe and record the dermoreaction for smearing position for 24 hours after each smear respectively.After test result shows removal tested material,
Zoopery position does not occur the anomalous variations such as erythema, oedema, and every animal integral mean value is 0 to the sample daily, to skin
Belong to non-stimulated.
In addition the present invention has also carried out multiple inspections such as toxicity level, teratospermia, Micronucleus experiment
The detection of survey project, test data are as follows：
Other performance test results of table 3
Clinical test is as follows：
It manufactures to obtain product according to the formula and production technology of embodiment 1,2,3, chooses the patients of different symptoms into enforcement
With test, including：After diaper rash, the skin injury caused by wound, burn and scald, summer body prickly heat, bite by mosquitos on skin
There is redness to itch the patients of the different symptoms such as pain, ewborn infant and childhood eczema, impetigo neonatorum, papular urticaria,
Using this product for a period of time after, have clear improvement.Product in Examples 1 to 3, which can be killed, causes mucocutaneous red and swollen, scabies
The germs of symptoms such as itch, be rotten to the corn, fester, suppurate.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
With within principle, any modification, equivalent replacement, improvement and so on should all be included in the protection scope of the present invention god.
Claims (5)
1. a kind of baby child's skin care compositions and methods, it is characterised in that：The skin care compositions and methods are by following mass percent
At being grouped as：
Poly hexamethylene biguanide 0.001 ~ 0.3%；
Chitosan 0.0005 ~ 1.0%；
Camellia flower extract 0.0005 ~ 0.5%；
Aloe extract 0.0005 ~ 0.5%；
Grape fruit extract 0.0005 ~ 0.5%；
Violet cabbage extract 0.0005 ~ 0.5%.
2. a kind of baby child's skin care compositions and methods according to claim 1, it is characterised in that：The skin care compositions and methods
By following mass percent at being grouped as：
Poly hexamethylene biguanide 0.001 ~ 0.3%；
Chitosan 0.0005 ~ 0.01%；
Camellia flower extract 0.0005 ~ 0.01%；
Aloe extract 0.0005 ~ 0.01%；
Grape fruit extract 0.0005 ~ 0.01%；
Violet cabbage extract 0.0005 ~ 0.01%；
Deionized water surplus.
3. a kind of baby child's skin care compositions and methods according to claim 1, it is characterised in that：The skin care compositions and methods
By following mass percent at being grouped as：
Poly hexamethylene biguanide 0. 1 ~ 0.3%；
Chitosan 0.0005 ~ 0.01%；
Camellia flower extract 0.0005 ~ 0.005%；
Aloe extract 0.0005 ~ 0.005%；
Grape fruit extract 0.0005 ~ 0.005%；
Violet cabbage extract 0.0005 ~ 0.005%；
Deionized water surplus.
4. a kind of preparation method of baby child's skin care compositions and methods, it is characterised in that：It comprises the following steps that：
(1) poly hexamethylene biguanide is added in the container for filling deionized water, stirs evenly, stands overnight；
(2) chitosan is added in the aqueous solution that is obtained to step (1), stirring makes it be uniformly mixed；
(3) camellia flower extract is added in the aqueous solution that is obtained to step (2), stirring makes it be uniformly mixed；
(4) aloe extract is added in the aqueous solution that is obtained to step (3), stirring makes it be uniformly mixed；
(5) grape fruit extract is added in the aqueous solution that is obtained to step (4), stirring makes it be uniformly mixed；
(6) violet cabbage extract is added in the aqueous solution that is obtained to step (5), stirring makes it be uniformly mixed, obtains product.
5. a kind of preparation method of baby child's skin care compositions and methods according to claim 4, it is characterised in that：The step
(2), mixing time is 30 ~ 90min in (3), (4), (5), (6).
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Cited By (5)
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| CN108743911A (en) * | 2018-08-09 | 2018-11-06 | 胥永贵 | A kind of sterilizing curing agent |
| CN110693801A (en) * | 2019-11-27 | 2020-01-17 | 湖南贝恩叮当猫婴童用品有限公司 | Shower gel for babies and children |
| CN110731910A (en) * | 2019-11-27 | 2020-01-31 | 湖南贝恩叮当猫婴童用品有限公司 | skin cream for infants and children |
| CN111904887A (en) * | 2020-09-08 | 2020-11-10 | 杭州可靠护理用品股份有限公司 | Skin health care composition and application thereof in paper diapers |
| CN113841637A (en) * | 2021-08-24 | 2021-12-28 | 中国水产科学研究院珠江水产研究所 | Hybrid snakehead rhabdovirus-free fry breeding method |
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| US8951583B2 (en) * | 2013-05-15 | 2015-02-10 | Normajean Fusco | Compositions for topical treatment |
| CN104367498A (en) * | 2013-08-16 | 2015-02-25 | 青岛道合生物科技有限公司 | Novel chitosan gel liquid for moisturizing and body caring |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108743911A (en) * | 2018-08-09 | 2018-11-06 | 胥永贵 | A kind of sterilizing curing agent |
| CN110693801A (en) * | 2019-11-27 | 2020-01-17 | 湖南贝恩叮当猫婴童用品有限公司 | Shower gel for babies and children |
| CN110731910A (en) * | 2019-11-27 | 2020-01-31 | 湖南贝恩叮当猫婴童用品有限公司 | skin cream for infants and children |
| CN111904887A (en) * | 2020-09-08 | 2020-11-10 | 杭州可靠护理用品股份有限公司 | Skin health care composition and application thereof in paper diapers |
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| CN113841637A (en) * | 2021-08-24 | 2021-12-28 | 中国水产科学研究院珠江水产研究所 | Hybrid snakehead rhabdovirus-free fry breeding method |
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