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CN108175802A - A kind of FUKANGBAO KOUFUYE and preparation method thereof - Google Patents

A kind of FUKANGBAO KOUFUYE and preparation method thereof Download PDF

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Publication number
CN108175802A
CN108175802A CN201810088144.5A CN201810088144A CN108175802A CN 108175802 A CN108175802 A CN 108175802A CN 201810088144 A CN201810088144 A CN 201810088144A CN 108175802 A CN108175802 A CN 108175802A
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parts
diacolation
liquid
water
fukangbao
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肖东
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CHONGQING RUEPEAK PHARMACEUTICAL Co Ltd
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CHONGQING RUEPEAK PHARMACEUTICAL Co Ltd
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Priority to CN201810088144.5A priority Critical patent/CN108175802A/en
Publication of CN108175802A publication Critical patent/CN108175802A/en
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Present invention mainly discloses a kind of FUKANGBAO KOUFUYEs and preparation method thereof, are made of the raw material of following parts by weight：15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, 12 parts of prepared rehmannia root, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae, 8 parts of brown sugar；Pre-processed by medicinal material, percolation extraction drug ingedient, the thick liquid concentration of diacolation, ethanol extract from water precipitation removal of impurities, the processes such as purified water oral liquid, it is of the invention to have the characteristics that preparation process is simple, easy to use, curative effect is high, at low cost.

Description

A kind of FUKANGBAO KOUFUYE and preparation method thereof
Technical field：
The present invention relates to a kind of oral liquid field, more particularly to a kind of FUKANGBAO KOUFUYE and preparation method thereof belongs to doctor Medicine field.
Background technology：
Oral solutions are based on traditional Chinese herbal decoction, extract active ingredient in drug, and it is additional to add in corrigent, bacteriostatic agent etc. Agent, and by injection ampoule encapsulation treatment process, manufactured a kind of sterile or half sterile oral liquid, therefore also known as mouth Take ampulla.It is a kind of new formulation that three kinds of decoction, syrup and injection dosage forms are combined.As SHENGMAI YIN KOUFUYE, Sini Tang oral liquid, ginseng antler royal jelly oral liquid etc..Its main feature is that taking dose is small, it is delicious, absorb it is fast, prove effective it is rapid, easily Received by patient.
Invention content：
The purpose of the present invention is to overcome the deficiencies of the prior art, provides a kind of FUKANGBAO KOUFUYE and its preparation side Method has the effect of tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention, and dizzy weak to sallow complexion, wrong after menstruation, amount polychrome is light, and menstrual period prolong Long, dysmenorrhoea and gynaecology's abdominal pain have the effect of good, and the present invention is with preparation process is simple, easy to use, curative effect is high, at low cost Feature.Solve the problems of the prior art.
To achieve the above object, the present invention provides following technical solution：A kind of FUKANGBAO KOUFUYE, by following parts by weight Raw material forms：It is Radix Angelicae Sinensis 5-15,6-16 parts of Radix Paeoniae Alba, 4-12 parts of Rhizoma Chuanxiong, 4-14 parts of prepared rehmannia root, 3-10 parts of folium artemisiae argyi, 6-16 parts of donkey-hide gelatin, sweet 5-10 parts careless, 4-12 parts of brown sugar；
Further, it is made of the raw material of following parts by weight：It is 10-15 parts of Radix Angelicae Sinensis, 8-15 parts of Radix Paeoniae Alba, 6-10 parts of Rhizoma Chuanxiong, ripe 6-12 parts of glutinous rehmannia, 5-10 parts of folium artemisiae argyi, 8-15 parts of donkey-hide gelatin, 5-10 parts of Radix Glycyrrhizae, 6-10 parts of brown sugar；
Further, it is made of the raw material of following parts by weight：15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, prepared rehmannia root 12 Part, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae, 8 parts of brown sugar；
Preparation method includes the following steps：
Step 1：Drug ingedient extracts
(1) medicinal material pre-processes：It takes above-mentioned without 15 parts putrid and deteriorated of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, prepared rehmannia root 12 Part, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae are put into pulverizer and crush, and the granular size after crushing is sieved by No. two, Drug granule after crushing is put into free of contamination container, adding in 70% ethyl alcohol makes it not have drug granule completely, seals After stand for 24 hours；
(2) percolation extraction drug ingedient：By treated in (1), herb in granule form is packed into diacolation bucket by several times, drug body Product is 2 with diacolation bucket volume ratio：3, then upper cover gauze, then the weights such as the clean microlith block of one layer of uniform fold or bead, After the completion of barrelling, 80% ethyl alcohol is slowly added to, mouth piston under diacolation bucket is opened and starts diacolation, diacolation process is constantly added new 80% ethyl alcohol, coutroi velocity 10L/h, the percolate of collection is the 8-10 times of thick liquid of obtained diacolation of drug gross weight；
Step 2：The thick liquid concentration of diacolation, to diacolation, thick liquid is concentrated under reduced pressure, and thickening temperature is 65-70 DEG C, steam pressure For 0.06-0.08Mpa, vacuum degree 0.06-0.10Mpa, control relative density of medicine liquid is in 1.00-1.15, the formation thick liquid of diacolation Concentrate；
Step 3：Alcohol extracting-water precipitating cleans, and will stir, adds while water is added after the ethyl alcohol recycling in the thick concentrated liquor of diacolation Water is 5-10 times of drug gross weight, after standing 12-24 hours in the environment of placing 5-10 DEG C after adding water, is put into and centrifuged Clarification concentrate is made in filtering 6-12h in filter；
Step 4：Oral liquid is prepared, concentrate is put into Agitation Tank, 8 dividend sugar is added in, adds concentrate and brown sugar The purified water that 2 times of gross weight is heated to boiling, and it is that brown sugar melts to stir 15 minutes, and micro-boiling keeps the temperature 15 minutes and forms liquid；It waits to mix It closes after uniform liquid is placed into room temperature and can be prepared by FUKANGBAO KOUFUYE of the present invention.
Preferably, the percolation is that herbal powder is mounted in percolator, constantly adds novel solvent, penetrates it Medicinal material is small when solvent infilters medicinal powder dissolved element proportion from a kind of leaching method of percolator lower part outflow leachate from top to bottom When increasing and moving down, its position is just replaced in the solution on upper strata or dilute immersion liquid, causes good concentration difference, makes diffusion energy preferable Ground carries out.
Preferably, dissolubility of the alcohol extracting-water precipitating removal of impurities according to various composition in medicinal material in water and ethyl alcohol, passes through water With the ethyl alcohol alternate treatment of various concentration, alkaloid salts, the active ingredients such as glycoside, amino acids, acylate can be retained；It goes The impurity such as isolating protein, starch, mucilaginous substance, grease, fat-soluble pigment, resin, natural gum.
Beneficial effects of the present invention：
It is a primary object of the present invention to provide a kind of FUKANGBAO KOUFUYE and preparation method thereof, production technology of the invention More demanding, technique is fine, and medicinal ingredient is extracted using percolation, in the case of retaining medicine effect ingredient, liquid extraction effect Rate and quality are improved, and remove the impurity in liquid using ethanol extract from water precipitation, liquid purity is high, therapeutic effect is notable.
4th, specific embodiment：
Technical solution in the embodiment of the present invention is clearly and completely described, it is clear that described embodiment is only Part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art All other embodiments obtained without making creative work shall fall within the protection scope of the present invention.
Embodiment：A kind of FUKANGBAO KOUFUYE is made of the raw material of following parts by weight：15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, Rhizoma Chuanxiong 10 parts, 12 parts of prepared rehmannia root, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae, 8 parts of brown sugar；
Preparation method includes the following steps：
Step 1：Drug ingedient extracts
(1) medicinal material pre-processes：It takes above-mentioned without 15 parts putrid and deteriorated of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, prepared rehmannia root 12 Part, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae are put into pulverizer and crush, and the granular size after crushing is sieved by No. two, Drug granule after crushing is put into free of contamination container, adding in 70% ethyl alcohol makes it not have drug granule completely, seals After stand for 24 hours；
(2) percolation extraction drug ingedient：By treated in (1), herb in granule form is packed into diacolation bucket by several times, drug body Product is 2 with diacolation bucket volume ratio：3, then upper cover gauze, then the weights such as the clean microlith block of one layer of uniform fold or bead, After the completion of barrelling, 80% ethyl alcohol is slowly added to, mouth piston under diacolation bucket is opened and starts diacolation, diacolation process is constantly added new 80% ethyl alcohol, coutroi velocity 10L/h, the percolate of collection is the 8-10 times of thick liquid of obtained diacolation of drug gross weight；
Step 2：The thick liquid concentration of diacolation, to diacolation, thick liquid is concentrated under reduced pressure, and thickening temperature is 65-70 DEG C, steam pressure For 0.06-0.08Mpa, vacuum degree 0.06-0.10Mpa, control relative density of medicine liquid is in 1.00-1.15, the formation thick liquid of diacolation Concentrate；
Step 3：Alcohol extracting-water precipitating cleans, and will stir, adds while water is added after the ethyl alcohol recycling in the thick concentrated liquor of diacolation Water is 5-10 times of drug gross weight, after standing 12-24 hours in the environment of placing 5-10 DEG C after adding water, is put into and centrifuged Clarification concentrate is made in filtering 6-12h in filter；
Step 4：Oral liquid is prepared, concentrate is put into Agitation Tank, 8 dividend sugar is added in, adds concentrate and brown sugar The purified water that 2 times of gross weight is heated to boiling, and it is that brown sugar melts to stir 15 minutes, and micro-boiling keeps the temperature 15 minutes and forms liquid；It waits to mix It closes after uniform liquid is placed into room temperature and can be prepared by FUKANGBAO KOUFUYE of the present invention.
The percolation is that herbal powder is mounted in percolator, constantly adds novel solvent, it is made to penetrate medicinal material, from It is upper and under from a kind of leaching method of percolator lower part outflow leachate it is small when solvent infilters the increasing of medicinal powder dissolved element proportion and When moving down, its position is just replaced in the solution on upper strata or dilute immersion liquid, causes good concentration difference, make diffusion energy preferably into Row；The dissolubility that the alcohol extracting-water precipitating cleans according to various composition in medicinal material in water and ethyl alcohol passes through water and various concentration Ethyl alcohol alternate treatment can retain alkaloid salts, the active ingredients such as glycoside, amino acids, acylate；It removes isolating protein, form sediment The impurity such as powder, mucilaginous substance, grease, fat-soluble pigment, resin, natural gum.
The basic principles, main features and the advantages of the invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its Equivalent thereof.

Claims (4)

1. a kind of FUKANGBAO KOUFUYE, which is characterized in that be made of the raw material of following parts by weight：15 parts of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, river 10 parts of rhizome of chuanxiong, 12 parts of prepared rehmannia root, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae, 8 parts of brown sugar.
2. a kind of preparation method of FUKANGBAO KOUFUYE, it is characterised in that：Include the following steps
Step 1：Drug ingedient extracts
(1) medicinal material pre-processes：Take it is above-mentioned without 15 parts putrid and deteriorated of Radix Angelicae Sinensis, 15 parts of Radix Paeoniae Alba, 10 parts of Rhizoma Chuanxiong, 12 parts of prepared rehmannia root, 10 parts of folium artemisiae argyi, 15 parts of donkey-hide gelatin, 10 parts of Radix Glycyrrhizae are put into pulverizer and crush, and the granular size after crushing, will by No. two sieves Drug granule after crushing is put into free of contamination container, and adding in 70% ethyl alcohol makes it not have drug granule completely, after sealing It stands for 24 hours；
(2) percolation extraction drug ingedient：Treated in (1) herb in granule form is packed into diacolation bucket by several times, injection volume with Diacolation bucket volume ratio is 2：3, then upper cover gauze, then the weights such as the clean microlith block of one layer of uniform fold or bead, barrelling After the completion, 80% ethyl alcohol is slowly added to, mouth piston under diacolation bucket is opened and starts diacolation, diacolation process constantly 80% new second of addition Alcohol, coutroi velocity 10L/h, the percolate of collection is the 8-10 times of thick liquid of obtained diacolation of drug gross weight；
Step 2：The thick liquid concentration of diacolation, to diacolation, thick liquid is concentrated under reduced pressure, and thickening temperature is 65-70 DEG C, and steam pressure is It is dense to form the thick liquid of diacolation in 1.00-1.15 for 0.06-0.08Mpa, vacuum degree 0.06-0.10Mpa, control relative density of medicine liquid Contracting liquid；
Step 3：Alcohol extracting-water precipitating cleans, and will be stirred while water is added after the ethyl alcohol recycling in the thick concentrated liquor of diacolation, amount of water It is 5-10 times of drug gross weight, after standing 12-24 hours in the environment of placing 5-10 DEG C after adding water, is put into filter centrifugal Clarification concentrate is made in interior filtering 6-12h；
Step 4：Oral liquid is prepared, concentrate is put into Agitation Tank, 8 dividend sugar is added in, adds concentrate and brown sugar gross weight 2 Purified water again is heated to boiling, and it is that brown sugar melts to stir 15 minutes, and micro-boiling keeps the temperature 15 minutes and forms liquid；It is to be mixed uniform Liquid be placed into room temperature after can be prepared by FUKANGBAO KOUFUYE of the present invention.
3. a kind of preparation method of FUKANGBAO KOUFUYE according to claim 2, it is characterised in that：The percolation be by Herbal powder is mounted in percolator, constantly adds novel solvent, it is made to penetrate medicinal material, is flowed out from top to bottom from percolator lower part A kind of leaching method of leachate is small to be increased and when solvent infilters medicinal powder dissolved element proportion when moving down, the solution on upper strata or Its position is just replaced in dilute immersion liquid, causes good concentration difference, and diffusion energy is made preferably to carry out.
4. a kind of preparation method of FUKANGBAO KOUFUYE according to claim 2, it is characterised in that：The alcohol extracting-water precipitating removes The miscellaneous dissolubility according to various composition in medicinal material in water and ethyl alcohol by the ethyl alcohol alternate treatment of water and various concentration, can protect Stay alkaloid salts, the active ingredients such as glycoside, amino acids, acylate；Remove isolating protein, starch, mucilaginous substance, grease, fat The impurity such as dissolubility pigment, resin, natural gum.
CN201810088144.5A 2018-01-30 2018-01-30 A kind of FUKANGBAO KOUFUYE and preparation method thereof Pending CN108175802A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748745A (en) * 2005-06-10 2006-03-22 湖南协力药业有限公司 Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method
CN1765392A (en) * 2005-09-02 2006-05-03 北京润德康医药技术有限公司 Chinese compound formulation for nourishing blood, regulating menstruation, stopping bleeding to prevent abortion and preparation method thereof
CN102552517A (en) * 2011-12-28 2012-07-11 武汉哈瑞医药有限公司 Gynecological sugar-free gynaecopathia treating particle and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748745A (en) * 2005-06-10 2006-03-22 湖南协力药业有限公司 Chinese medicine granular powder for tonifying blood and regulating menstruation, arresting bleeding and miscarriage prevention and its preparing method
CN1765392A (en) * 2005-09-02 2006-05-03 北京润德康医药技术有限公司 Chinese compound formulation for nourishing blood, regulating menstruation, stopping bleeding to prevent abortion and preparation method thereof
CN102552517A (en) * 2011-12-28 2012-07-11 武汉哈瑞医药有限公司 Gynecological sugar-free gynaecopathia treating particle and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
全国中等卫生学校试用教材《药剂学》编写组: "《全国中等卫生学校试用教材 药剂学》", 31 May 1980, 浙江科学技术出版社 *
李瑶卿等: "《小病上药店-国家非处方中成药简明手册》", 31 August 2002, 江西科学技术出版社 *

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Application publication date: 20180619