CN108030808A - A kind of pulvis using lotus leaf as the prevention Diseases of Cow syndrome of main component - Google Patents

Abstract

The invention mainly uses lotus leaf and some antioxidant substances to prevent and treat a series of syndromes caused by ketosis in dairy cows in the perinatal period. The main function is to prevent some postpartum diseases that are susceptible to postpartum cows due to improper feeding management and physiological factors of the cows themselves. The main groups are calcium gluconate, potassium gluconate, iodized salt, propylene glycol, vitamin A, vitamin D, vitamin E, vitamin B ₁₂ , niacin, carotenoids, and nuciferine. It mainly prevents postpartum paralysis, postpartum hemorrhage, retained placenta, cow ketosis, dislocation of abomasum, decreased milk production, fatty liver, and endometritis. The components of the invention are strictly safe, simple to manufacture, easy to obtain, and low in production cost, and can timely supplement the nutrition and trace elements required by postpartum cows, and have a good effect on preventing postpartum syndrome of dairy cows. It can greatly reduce the cost of breeding and has high economic benefits.

Description

A powder for preventing and treating peripartum dairy cow syndrome with lotus leaf as the main component

technical field

The invention belongs to the technical field of animal husbandry.

Background technique

The perinatal period is a very important stage for dairy cows. Due to the effect of pregnancy, the dry matter intake of dairy cows in the perinatal period decreases, and the body needs a lot of energy for the body to consume and to synthesize various proteins and the fetus. Some substances are necessary, and this energy demand is greater than the supply to become a negative energy balance. Under the negative energy balance, the body can only use fat decomposition in the body to provide the energy needed by the body and synthesize various substances needed. Finally, fat mobilization intensifies and free fatty acids increase. There are three main outlets for fatty acids: 1) complete oxidation to generate CO _{2 ,} and water provide energy for the body. 2) Incomplete oxidation to generate ketone bodies, a large amount of free fatty acids in the blood are oxidized and decomposed into acetyl-CoA for energy supply in the liver tissue. Due to the reduction in food intake, the oxaloacetate that can combine with acetyl-CoA in the body decreases, and eventually too much acetyl-CoA Synthetic ketone bodies are acetoacetate, β-hydroxybutyrate, and acetone. 3) Esterification again to form triglycerides. Due to the low glucose concentration in dairy cows with less dry matter intake, a large amount of ketone bodies produced by the liver are left behind after meeting the body's needs, resulting in ketosis.

During the peripartum period, dairy cows undergo a series of physiological changes from pregnancy to parturition to lactation, coupled with diet switching, etc., which lead to a decrease in dry matter intake, and at the same time lactation starts, energy demand increases, and they are in a state of negative energy balance. The single or combined effects of the above factors can lead to endocrine and immune dysfunction in dairy cows, which greatly increases the risk of dairy cows suffering from production diseases (such as fatty liver, ketosis and hypocalcemia, etc.). When ketosis occurs, the ketone body not only accumulates a large amount of ketone bodies, but also produces a large amount of active oxygen when forming ketone bodies. A large amount of active oxygen will cause a lot of damage to the body and cause many diseases. These diseases often have a disproportionate impact on dairy cows by causing reduced milk production and performance, resulting in increased culling rates and veterinary treatment costs.

Insufficient dry matter intake of dairy cows during the peripartum period makes the minerals (such as calcium, magnesium, potassium, etc.) required by dairy cows insufficient to meet the needs of the body, and the continuous lactation of dairy cows requires a large amount of minerals to meet the needs of the body. If these minerals are not supplemented in time in the diet, the dairy cows are prone to mineral deficiencies such as hypocalcemia and hypomagnesemia, and then the uterine contraction is weak due to the lack of calcium ions when the cows are calving, resulting in retained placenta. paralysis.

Dairy cattle breeding in contemporary my country is an intensive large-scale breeding industry, but due to its late start, many breeding levels are low. During the transition period, dairy cows experience a series of physiological changes from pregnancy to parturition to lactation, coupled with dietary changes, which lead to a decrease in dry matter intake, and at the same time lactation starts, energy demand increases, and they are in a state of negative energy balance. The single or superimposed effects of the above factors can lead to endocrine and immune dysfunction of dairy cows, resulting in decreased immune resistance of dairy cows. In addition, improper postpartum care makes dairy cows prone to endometritis and other inflammations of the birth canal, thereby reducing the next conception rate of dairy cows. The dairy industry causes huge economic losses.

Contents of the invention

The purpose of the present invention is to prevent and treat a series of syndromes caused by ketosis in dairy cows during the peripartum period by using lotus leaves, spirulina rich in β-carotene and a special formula of some trace elements with lotus leaves as the main component. Powder for Peripartum Cow Syndrome.

The parts by weight that the present invention forms active ingredient is:

Calcium gluconate 25-38 Vitamin A 5-7 Lotus leaf 266—400

Potassium Gluconate 20-32 Vitamin D 2-4 Spirulina 10-16

Magnesium propionate 12-20 Vitamin E 4-6 Milk powder 5-10

Iodized salt 9-10 Baking soda 18-20.

The parts by weight that the present invention forms active ingredient is:

Calcium gluconate 38 Vitamin A 7 Lotus leaf 266

Potassium Gluconate 32 Vitamin D 2 Spirulina 10

Magnesium propionate 20 Vitamin E 6 Milk powder 10

Iodized table salt 9

baking soda 19.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 36 Vitamin A 7 Lotus Leaf 300

Potassium Gluconate 30 Vitamin D 2 Spirulina 11

Magnesium propionate 20 Vitamin E 6 Milk powder 8

Iodized table salt 10

baking soda 19.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 30 Vitamin A 6 Lotus Leaf 350

Potassium Gluconate 25 Vitamin D 3 Spirulina 13

Magnesium propionate 20 Vitamin E 5 Milk powder 7

Iodized table salt 9.5

Baking soda 20.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 25 Vitamin A 5 Lotus Leaf 400

Potassium Gluconate 20 Vitamin D 4 Spirulina 16

Magnesium Propionate 18 Vitamin E 4 Milk Powder Servings 5

Iodized table salt 10

baking soda 18.

The present invention can effectively solve the problems existing in the technical background, so that dairy cows can safely pass through the perinatal period, and the raw materials of the present invention are extremely easy to obtain and the price is extremely low. While ensuring the health of dairy cows, it can greatly reduce the cost of breeding and increase the income of breeding enterprises . The invention uses lotus leaf and spirulina as the main components to prevent and treat a series of postpartum syndrome diseases such as ketosis, decreased milk production, and postpartum paralysis in dairy cows during the peripartum period, which is the first case in China. Through research on the above-mentioned milk cows prone to diseases and analysis of the comprehensive pathogenesis of this product, the research of multiple aspects such as pathogenesis, the present invention adds nutrients for the perinatal period to supplement various nutrients that are lacking. At the same time, add nuciferine, spirulina rich in β-carotene and a special formula of some trace elements to prevent and treat clinical ketosis, decreased milk production, postpartum paralysis, retained placenta and postpartum dairy cow birth canal inflammation and to a certain extent improve conception rate.

Detailed ways

The parts by weight that the present invention forms active ingredient is:

Calcium gluconate 25-38 Vitamin A 5-7 Lotus leaf 266—400

Potassium Gluconate 20-32 Vitamin D 2-4 Spirulina 10-16

Magnesium propionate 12-20 Vitamin E 4-6 Milk powder 5-10

Iodized salt 9-10 Baking soda 18-20;

It is prepared by conventional powder preparation method.

The parts by weight that the present invention forms active ingredient is:

Calcium gluconate 38 Vitamin A 7 Lotus leaf 266

Potassium Gluconate 32 Vitamin D 2 Spirulina 10

Magnesium propionate 20 Vitamin E 6 Milk powder 10

Iodized table salt 9

baking soda 19;

It is prepared by conventional powder preparation method.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 36 Vitamin A 7 Lotus Leaf 300

Potassium Gluconate 30 Vitamin D 2 Spirulina 11

Magnesium propionate 20 Vitamin E 6 Milk powder 8

Iodized table salt 10

baking soda 19;

It is prepared by conventional powder preparation method.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 30 Vitamin A 6 Lotus Leaf 350

Potassium Gluconate 25 Vitamin D 3 Spirulina 13

Magnesium propionate 20 Vitamin E 5 Milk powder 7

Iodized table salt 9.5

Baking soda 20;

It is prepared by conventional powder preparation method.

The parts by weight that the present invention forms active ingredient is:

Calcium Gluconate 25 Vitamin A 5 Lotus Leaf 400

Potassium Gluconate 20 Vitamin D 4 Spirulina 16

Magnesium Propionate 18 Vitamin E 4 Milk Powder Servings 5

Iodized table salt 10

baking soda 18;

It is prepared by conventional powder preparation method.

Components of the treatment group of the present invention: (the following are all prepared by conventional powder preparation methods)

Treatment group A:

38 parts of calcium gluconate, 7 parts of vitamin A, 266 parts of lotus leaf

Potassium gluconate 32 parts Vitamin D 2 parts Spirulina 10 parts

Magnesium propionate 20 parts Vitamin E 6 parts Milk powder 10 parts

9 parts iodized table salt

19 parts baking soda

Treatment group B:

36 parts of calcium gluconate, 7 parts of vitamin A, 300 parts of lotus leaf

Potassium gluconate 30 parts Vitamin D 2 parts Spirulina 11 parts

20 parts of magnesium propionate, 6 parts of vitamin E, 8 parts of milk powder

10 parts iodized salt

19 parts baking soda

Treatment group C:

30 parts of calcium gluconate, 6 parts of vitamin A, 350 parts of lotus leaf

Potassium gluconate 25 parts Vitamin D 3 parts Spirulina 13 parts

20 parts of magnesium propionate, 5 parts of vitamin E, 7 parts of milk powder

9.5 parts iodized table salt

20 parts baking soda

Treatment group D:

25 parts of calcium gluconate, 5 parts of vitamin A, 400 parts of lotus leaf

Potassium gluconate 20 parts Vitamin D 4 parts Spirulina 16 parts

Magnesium propionate 18 parts Vitamin E 4 parts Milk powder 5 parts

10 parts iodized salt

Baking soda 18 parts

The present invention can effectively solve the problems existing in the technical background, so that dairy cows can safely pass through the perinatal period, and the raw materials of the present invention are extremely easy to obtain and the price is extremely low. While ensuring the health of dairy cows, it can greatly reduce the cost of breeding and increase the income of breeding enterprises .

The main feature of the invention is that lotus leaves, spirulina rich in beta-carotene and some trace elements are added to the special formula to prevent and treat a series of syndromes caused by ketosis in dairy cows during the transition period. Lotus leaf is a plant of Nymphaeaceae. Traditional Chinese medicine believes that its nature and flavor are bitter and astringent, calm, and it returns to the liver, lungs, stomach, and heart meridian. In addition, a large number of studies have proved that the rich nuciferine and flavonoids in lotus leaves have antibacterial and bactericidal effects, and also have antioxidant effects.

The main highlight of the product of the present invention is the addition of lotus leaf and spirulina. A large amount of nuciferine contained in lotus leaf has an inhibitory effect on the body’s inflammatory response, mainly through the combination of nuciferine molecules and inflammatory activators to make it lose its interaction with inflammatory cells. Therefore, inflammatory cells cannot release a large number of inflammatory factors and play an anti-inflammatory role. At the same time, lotus leaves are also rich in flavonoids, which are scavengers of most oxygen free radicals, can increase the activity of superoxide dismutase, reduce the generation of malondialdehyde and oxidized low-density lipoprotein, a large number of experiments have proved Nuciferine has antibacterial effect. Nuciferine can inhibit bacterial mitosis or affect cell energy metabolism by destroying bacterial cell walls and cell membranes to achieve antibacterial and bactericidal effects. Thereby reducing the postpartum inflammation of dairy cows due to bacterial infection. From the perspective of traditional Chinese medicine, dairy cows have postpartum qi deficiency and blood deficiency, while lotus leaves are mainly used to treat postpartum qi deficiency and blood stasis, and have the effects of stopping bleeding, regulating the spleen and strengthening the stomach. It can quickly stop the postpartum bleeding of dairy cows and prevent secondary infection of dairy cows. The β-carotene rich in spirulina has anti-oxidation effect, and a large amount of reactive oxygen species will be produced in the body when cows undergo ketosis during the peripartum period, causing damage to the machine, especially the liver damage is more serious, which exacerbates the imbalance between oxidation and anti-oxidation in the body , and perinatal supplementation of antioxidant substances can effectively alleviate the damage caused by excessive active oxygen in the body.

The method of using the powder of the present invention: cows are fed once a week from 21 days before delivery to 21 days after delivery, take a bag of this product and add it to 5-10kg 37°C water before eating every Monday, and then pour it into the rumen, and other The feeding process is normal. Continuously fed 6 times once a week.

The main preventive and therapeutic principles and beneficial effects of the present invention are: this product uses calcium gluconate and potassium gluconate, which are easy to purchase and cheap, not only timely supplement the glucose needed in the perinatal dairy cows, but also can provide the dry matter intake of dairy cows. Insufficient calcium and potassium ions prevent dairy cows from suffering from hypocalcemia and hypokalemia. Magnesium propionate also provides propionic acid for the rumen of dairy cows so that the cows can use propionic acid for gluconeogenesis to synthesize other substances needed by the body. Magnesium ions can effectively prevent hypomagnesemia in dairy cows and magnesium propionate is easily absorbed. Various vitamins can effectively supplement the nutritional substances that dairy cows lack during the transition period due to insufficient dry matter intake. The highlight of this product is the addition of lotus leaf and milk powder spirulina. Nuciferine contained in lotus leaves can effectively inhibit bacteria (excluding beneficial bacteria in the rumen), and lotus leaves are also effective in treating postpartum qi deficiency, blood stasis, and blood deficiency in dairy cows in traditional Chinese medicine. It also has the effect of regulating the spleen and strengthening the stomach. Nuciferine plays a better role under certain conditions, so adding soda powder. Spirulina contains a large amount of β-carotene, which has anti-inflammatory and antioxidant effects. The main components of milk protection powder are: vitamin E: selenium = 1236IU: 54㎎, vitamin B ₁₂ 5㎎, niacin 4㎎, which can effectively increase the milk production of dairy cows during the peripartum period and increase the conception rate. The main highlight of the product of the present invention is the addition of lotus leaf and spirulina. A large amount of nuciferine contained in lotus leaf has an inhibitory effect on the body’s inflammatory response, mainly through the combination of nuciferine molecules and inflammatory activators to make it lose its interaction with inflammatory cells. Therefore, inflammatory cells cannot release a large number of inflammatory factors and play an anti-inflammatory role. At the same time, lotus leaves are also rich in flavonoids, which are scavengers of most oxygen free radicals, can increase the activity of superoxide dismutase, reduce the generation of malondialdehyde and oxidized low-density lipoprotein, a large number of experiments have proved Nuciferine has antibacterial effect. Nuciferine can inhibit bacterial mitosis or affect cell energy metabolism by destroying bacterial cell walls and cell membranes to achieve antibacterial and bactericidal effects. Thereby reducing the postpartum inflammation of dairy cows due to bacterial infection. From the perspective of traditional Chinese medicine, dairy cows have postpartum qi deficiency and blood deficiency, while lotus leaves are mainly used to treat postpartum qi deficiency and blood stasis, and have the effects of stopping bleeding, regulating the spleen and strengthening the stomach. It can quickly stop the postpartum bleeding of dairy cows and prevent secondary infection of dairy cows. The β-carotene rich in spirulina has anti-oxidation effect, and a large amount of reactive oxygen species will be produced in the body when cows undergo ketosis during the peripartum period, causing damage to the machine, especially the liver damage is more serious, which exacerbates the imbalance between oxidation and anti-oxidation in the body , and perinatal supplementation of antioxidant substances can effectively alleviate the damage caused by excessive active oxygen in the body. This product has undergone a large number of experiments to optimize the combination to be scientific and reasonable, with high safety and remarkable effect.

The raw materials of this product are easy to obtain, the price is lower than that of cows, and the taste is better. It is simple, safe and effective to use. Research from the perspective of nutrition and pathogenesis can effectively prevent and treat peripartum cow ketosis, decreased milk production, postpartum paralysis and postpartum endometritis, and can increase the conception rate to a certain extent, and the above effects in the experiment have all been verified. In dairy farming, the work of veterinarians is greatly reduced, and the income of farming enterprises is increased.

Because this product is fed before eating, it is easy to insert the gastric catheter into the organ or lung during feeding, so it needs to be operated by personnel with certain veterinary knowledge or supervised by professional veterinary personnel or have certain operating experience. old technician.

In order to further confirm the effect of this product, the following nine groups of experiments were carried out. The specific operations and instructions are as follows:

This experiment adopts the step-by-step scheme of control group, prevention group and treatment group.

Selection and grouping of experimental animals: Select an intensive dairy farm with 10,000 cows, 320 cows with parity, age, body condition and expected date of delivery are very close to healthy cows. Divided into four control groups, 40 animals in each group, 160 animals in the experimental group, marked as prevention group 1, 40 animals, prevention group 2, 40 animals, prevention group 3, 40 animals, prevention group 4, 40 animals.

Both the experimental group and the control group were fed according to NRC standards. From 21 days before the expected date of delivery to 21 days after delivery, they were fed once a week. Before eating every Monday, take a bag of this product and add it to 5-10kg of water at 37°C, and then feed Serve in the rumen, other feeding processes are normal. Continuously fed 6 times once a week.

Experimental operation: Experimental groups 1, 2, 3, and 4 correspond to the amount of this product in prevention groups 1, 2, 3, and 4, respectively.

Within 42 days, the control group and the prevention group were fed equally according to the NRC standard. Blood was collected every day to detect ketosis and inflammation of the birth canal, and the average milk production of cows per week was recorded and whether the cows were paralyzed. Every step was done carefully, and the results were counted after 42 days. .

Results of 42 consecutive days of testing:

Implementation results of prevention group 1:

The number of cases of ketosis, postpartum paralysis, and inflammation of the birth canal in the two groups

.

Statistical results of milk production (unit: L/average per head):

.

Implementation results of prevention group 2:

The number of cases of ketosis, postpartum paralysis, and inflammation of the birth canal in the two groups

.

Statistical results of milk production (unit: L/average per head):

.

Implementation results of prevention group 3:

Number of cases of ketosis, postpartum paralysis, and inflammation of the birth canal in the two groups:

.

Statistical results of milk production (unit: L/average per head):

.

Implementation results of prevention group 4:

Number of cases of ketosis, postpartum paralysis, and inflammation of the birth canal in the two groups:

.

Statistical results of milk production (unit: L/average per head):

.

Through the analysis of clinical cases, the following conclusions can be drawn by using SPASS 19.0 software and t test for analysis:

Adopting the product of the invention can effectively prevent dairy cow ketosis, and the product is very effective in preventing clinical ketosis compared with the control group. And the difference between the prevention group 4 and the control group was extremely significant (P<0.001), and the incidence of ketosis was reduced by 65%. , postpartum paralysis decreased by 35%, postpartum birth canal inflammation decreased by 57.5%, and the average milk production of dairy cows increased by 49.61%. Therefore, it can be shown that this product has a very good effect on preventing ketosis and increasing milk production in dairy cows during the peripartum period.

After the above experiment was over, the same grouping of the experimental subjects used in this experiment was used to observe the conception rate of the first fertilized dairy cows in the later five groups, and the feeding conditions of the prevention group and the control group were exactly the same. The result is as follows:

The conception is as follows:

.

The experimental results show that the conception of dairy cows after giving birth is significantly different between using this product and not using this product. The use of this product can greatly increase the conception rate, and the conception rate of the prevention group 4 reached 97.5%. Therefore, it can be proved that feeding the product during the perinatal period of the present invention can not only prevent dairy cow ketosis but also improve the postpartum conception rate.

Test the therapeutic effect of this product The specific implementation plan is as follows:

Select 200 postpartum dairy cows with the same parity, age, body condition and other physical conditions in an intensive dairy farm with 10,000 cows, and confirm the diagnosis by various biochemical indicators (BHBA>1.2mmol/L; GLU<2.5mmol/L;) For ketosis. Divided into four control groups with 40 heads in each group and an experimental group with 160 heads, labeled as treatment group A with 40 heads, treatment group B with 40 heads, treatment group C with 40 heads, and treatment group D with 40 heads.

The experiment is divided into a treatment group and a control group. The control group does not add this product, and the control group adds the product of the present invention and adds this product according to the amount of the treatment group in 2. Feed once every 5 days and detect the ketosis indicators BHBA, NEFA, AST, ALT, GLU in the blood of dairy cows the night before feeding, continuously feed for 30 days, and detect 6 blood samples. The statistics of the experimental results are as follows:

BHBA test results (unit: mmol/L):

.

NEFA test results (unit: mmol/L)

.

GLU test results (unit: mmol/L)

.

AST test results (unit: mmol/L)

.

ALT test results (unit: mmol/L)

.

The experimental results were analyzed by t test using SPASS19.0 software, and it was found that the experimental group and the control group were significantly different (P<0.05), and the treatment group 3, 4, and the two groups were significantly different (P<0.01), so this experiment is completely It is proved that the product of the invention can effectively cure cow ketosis.

It has been strongly proved by experiments that the present invention has remarkable effects in preventing and treating peripartum milk-prone ketosis, postpartum paralysis, retained placenta and inflammation of the birth canal. Among them, formula 4 is the most optimized formula combination. Moreover, the product can improve the conception rate of dairy cows after the peripartum period, and has important use value for the dairy cattle breeding industry. Moreover, the product is green, environmentally friendly, safe, efficient, and low in price, and its application in the animal husbandry industry can bring huge economic benefits to it.

The main highlight of the product of the present invention is the addition of lotus leaf and spirulina. A large amount of nuciferine contained in lotus leaf has an inhibitory effect on the body’s inflammatory response, mainly through the combination of nuciferine molecules and inflammatory activators to make it lose its interaction with inflammatory cells. Therefore, inflammatory cells cannot release a large number of inflammatory factors and play an anti-inflammatory role. At the same time, lotus leaves are also rich in flavonoids, which are scavengers of most oxygen free radicals, can increase the activity of superoxide dismutase, reduce the generation of malondialdehyde and oxidized low-density lipoprotein, a large number of experiments have proved Nuciferine has antibacterial effect. Nuciferine can inhibit bacterial mitosis or affect cell energy metabolism by destroying bacterial cell walls and cell membranes to achieve antibacterial and bactericidal effects. Thereby reducing the postpartum inflammation of dairy cows due to bacterial infection. From the perspective of traditional Chinese medicine, dairy cows have postpartum qi deficiency and blood deficiency, while lotus leaves are mainly used to treat postpartum qi deficiency and blood stasis, and have the effects of stopping bleeding, regulating the spleen and strengthening the stomach. It can quickly stop the postpartum bleeding of dairy cows and prevent secondary infection of dairy cows. The β-carotene rich in spirulina has anti-oxidation effect, and a large amount of reactive oxygen species will be produced in the body when cows undergo ketosis during the peripartum period, causing damage to the machine, especially the liver damage is more serious, which exacerbates the imbalance between oxidation and anti-oxidation in the body , and perinatal supplementation of antioxidant substances can effectively alleviate the damage caused by excessive active oxygen in the body.

Claims (5)

1. A kind of 1. pulvis using lotus leaf as the prevention Diseases of Cow syndrome of main component, it is characterised in that：Composition effectively into Part parts by weight be：

   Calcium gluconate 25-38 vitamin A 5-7 lotus leaves 266-400

   K-IAO 20-32 vitamin D 2-4 spirulinas 10-16

   Propionic acid magnesium 12-20 vitamin Es 4-6 protects milk powder 5-10

   Iodized salt 9-10 soda ash 18-20.
2. 2. the pulvis according to claim 1 using lotus leaf as the prevention Diseases of Cow syndrome of main component, its feature It is：Forming the parts by weight of effective ingredient is：

   38 vitamin A of calcium gluconate, 7 lotus leaf 266

   32 vitamin D of K-IAO, 2 spirulina 10

   20 vitamin E 6 of propionic acid magnesium protects milk powder 10

   Iodized salt 9

   Soda ash 19.
3. 3. the pulvis according to claim 1 using lotus leaf as the prevention Diseases of Cow syndrome of main component, its feature It is：Forming the parts by weight of effective ingredient is：

   36 vitamin A of calcium gluconate, 7 lotus leaf 300

   30 vitamin D of K-IAO, 2 spirulina 11

   20 vitamin E 6 of propionic acid magnesium protects milk powder 8

   Iodized salt 10

   Soda ash 19.
4. 4. the pulvis according to claim 1 using lotus leaf as the prevention Diseases of Cow syndrome of main component, its feature It is：Forming the parts by weight of effective ingredient is：

   30 vitamin A of calcium gluconate, 6 lotus leaf 350

   25 vitamin D of K-IAO, 3 spirulina 13

   20 vitamin E 5 of propionic acid magnesium protects milk powder 7

   Iodized salt 9.5

   Soda ash 20.
5. 5. the pulvis according to claim 1 using lotus leaf as the prevention Diseases of Cow syndrome of main component, its feature It is：Forming the parts by weight of effective ingredient is：

   25 vitamin A of calcium gluconate, 5 lotus leaf 400

   20 vitamin D of K-IAO, 4 spirulina 16

   18 vitamin E 4 of propionic acid magnesium protects milk powder part 5

   Iodized salt 10

   Soda ash 18.