CN106721305A - It is a kind of to improve compositions of additives of body condition or its production performance and preparation method thereof after Farrowing - Google Patents

Abstract

The invention provides an additive composition capable of improving body condition or production performance of sows after delivery, which is composed of raw materials in the following weight ratio: 1-2 parts of thymol, 4-6 parts of cinnamaldehyde, 11 parts of amino acid ‑13 servings, vitamin 6‑8 servings. The invention also provides the preparation method and application of the composition. The feed additive of the present invention can effectively improve the body condition of the sow after delivery, restore the health of the mother, improve the immunity of the sow, and at the same time improve the breast milk, ensure the health of the piglet, and increase the weaning survival; in addition, the use of this type of additive can alleviate the environmental impact caused by the use of antibiotics. The pressure brought by it will bring benefits to the pig industry.

Description

An additive composition capable of improving body condition or production performance of sows after delivery and its preparation method

technical field

The patent relates to a feed additive for pigs, in particular to an additive combination for improving body condition and production performance of sows after delivery, and belongs to the field of feed additives.

Background technique

The health of sows has always been an important factor affecting the development of the pig breeding industry. After giving birth, the body of sows is in a sub-healthy state or below, and the body's resistance is greatly weakened. At this time, it is vulnerable to various diseases or pathogenic microorganisms, which seriously restricts The production of sows is affected, which ultimately affects the sustainable development of the pig breeding industry. In the past few decades, the production performance of breeding sows in my country has been at a low level, and the litter size, healthy piglet size, and lactation survival rate of sows are all lower than the European average. Through various means such as breed improvement, nutritional regulation, and disease prevention and control, the reproductive performance of sows has been greatly improved, and the litter size, piglet birth weight, and weaning survival rate have all been greatly improved. Thanks to the discovery and use of antibiotic drugs. However, with the extensive use of antibiotics, problems such as bacterial resistance, host flora disorder, drug residues, and environmental damage cannot be ignored; the European Union began to completely ban the use of any antibiotics on livestock and poultry as early as 2006. Although my country has not yet Prohibition regulations have been issued, but antibiotics will also withdraw from the domestic animal husbandry stage in the near future. Therefore, actively looking for a safe and effective alternative to antibiotics has become one of the urgent tasks today.

From gestation 95d to delivery, the ratio of fetal weight gain to birth weight is relatively high (about 39%), and the embryonic mortality rate at this stage is 5% to 10%. In addition, the feeding and management level of sows during pregnancy greatly affects the continuous production capacity of lactating sows, newborn piglets, weaned piglets and sows; "Food management according to the law, and appropriate fetal tapping (feeding) starts at the 95th day of pregnancy; the purpose of fetal tapping in the late pregnancy is to increase the feed intake of lactating sows on the one hand, so that the total daily nutrient intake of lactating sows reaches the level of milk production. Basic needs; on the other hand, it is also to appropriately increase the birth weight of piglets, ensure the health of the fetus, and increase the number of live piglets.

Emulsion is the source of life for suckling piglets. The emulsion is rich in complex high-nutrient substances, and there are a large number of active ingredients that promote the development of piglets’ intestines, their own growth, and the construction of their own immune system, such as IgG, IgM, IGF-1, etc. Especially colostrum. Newborn piglets have low self-reserved energy and lack of immune defense ability; generally speaking, when piglets suck breast milk in the early lactation period, most active substances in the emulsion can directly enter the body through the intestinal wall, which actually plays a role in enhancing the piglet’s immune ability and promoting growth. Function; However, in the middle and late stages of lactation, the piglet's own immune defense system is basically perfect, and the environment in the intestinal tract tends to be stable at this time. At this time, the growth rate of the body is accelerated, and breast milk is more needed for supplementation. Therefore, the content of nutrients and non-nutrients in lactating sow milk is particularly important for suckling piglets, which affects the growth and development of suckling piglets to a certain extent, and affects the health of piglets, and ultimately affects weaning survival.

Plant essential oil is a class of volatile aromatic substances extracted from the roots, stems, branches, leaves, and fruits of vegetation by distillation, pressing, and solvent extraction. Cancer, insecticide and other biological effects. Nowadays, plant essential oils have been widely used in many fields such as food, medical treatment, agriculture and animal husbandry; plant essential oils have complex components, and tens of thousands of plant essential oils have been reported and discovered so far. Thymol and cinnamaldehyde are both components of plant essential oils. Under normal feeding doses, they have no damage to the body and no toxic or side effects; adding this essential oil to the diet can be completely absorbed by the gastrointestinal wall of the animal and enter the body. Participate in the regulation of body metabolism, affect blood circulation, play an important role in transporting oxygen and nutrients to the body, and excrete cell metabolites; the other part is excreted from the body in the form of safe products without any impact on the environment; Essential oils, but synthetic essential oils are much less active than natural essential oils.

Essential amino acids are a class of organic compounds that cannot be synthesized by the body itself or cannot meet the growth needs of the body; lysine, as the first limiting amino acid for pigs, is particularly important for the production of breeding sows and the protection of their own health. Vitamins are a class of low-molecular-weight organic substances that are necessary for animal metabolism or require very little. Generally, animal organisms cannot synthesize vitamins and need to be supplemented through dietary intake. VA is a fat-soluble vitamin. After entering the body, it participates in the metabolism and regulation of the body, and also has a certain impact on maintaining the normality of the digestive tract epithelial cells, animal reproduction and immune regulation; An important coenzyme of the carrier protein, which is related to the metabolism of carbohydrates, fats and amino acids in the body and many chemical reactions in the cell; while folic acid is an indispensable carrier for the transfer of one-carbon groups, it participates in the synthesis of DNA and choline in the body, and affects the red blood cells. The formation and regulation of the immune function of the body. However, in actual breeding, due to the low effective dose of the raw material itself, coupled with a series of uncertain factors such as storage, production and processing, feeding management, and weather changes, the effective content of such substances actually obtained by sows is greatly reduced. Failure to meet the body's metabolic needs hinders sow production.

Application number: 201510980198.9, Invention name: Pig feed additive for improving pork quality and its preparation method, discloses a pig feed additive for improving pork quality and its preparation method, which includes: cinnamaldehyde 15% to 22% by mass percentage; parsley Phenol 4%~8%; Thymol 0.5%~1.5%; Eugenol 0.5%~1.5%; Lycopene 2%~5%; Vitamin D30.008%~0.01%; Creatine 0.005%~0.01%; Sulfuric acid Magnesium 0.01% to 0.02%; antioxidant 1% to 3%; carrier 66% to 70%. The cinnamaldehyde, carvacrol, thymol, eugenol, and lycopene contained in this invention all have antioxidant properties, exert the anti-oxidation function in cells, and finally protect the body from oxidative stress damage, making the flesh color more Bright red; vitamin D3 is not simply a vitamin, it mainly plays a role in improving the meat color and tenderness of pork; creatine is a functional amino acid, it mainly plays a role in relieving slaughter stress, improving pork pH and reducing drip loss, etc. function, the patent solution is aimed at how to improve the meat quality of fattened pigs.

Contents of the invention

The technical problem of the present invention is to provide a new feed additive for pigs. Another technical solution of the present invention is to provide a preparation method of the additive.

The invention provides an additive composition capable of improving body condition or production performance of sows after delivery, which is composed of raw materials with the following weight ratios:

1-2 parts of thymol, 4-6 parts of cinnamaldehyde, 11-13 parts of amino acids, 6-8 parts of vitamins.

Wherein, the amino acid is one or a mixture of L-lysine and threonine; the vitamin is one or a mixture of vitamin A, folic acid, and pantothenic acid.

Wherein, it is made up of the raw material of following weight ratio:

1-2 parts of thymol, 4-6 parts of cinnamaldehyde, 6-8 parts of L-lysine, 4-6 parts of threonine, 3-4 parts of vitamin A, 0.4-0.6 parts of folic acid, 3-4 parts of pantothenic acid.

Further preferably, it is composed of the following raw materials in weight ratio:

Thymol 1.8 parts, cinnamaldehyde 5.4 parts, L-lysine 7.5 parts, threonine 5.2 parts, vitamin A 3.5 parts, folic acid 0.5 parts, pantothenic acid 3.75 parts.

Wherein, there is also a carrier in the raw materials, and the carrier is composed of stone powder and dextrin powder in a mass ratio of 1:3-5.

Further preferably, the carrier is composed of stone powder and dextrin powder mixed in a ratio of 1:4.

Wherein, the carrier is crushed through a 40-mesh sieve.

The present invention also provides a preparation method for preparing the composition, which comprises the steps of:

Thymol, cinnamaldehyde, L-lysine, threonine, vitamin A, folic acid and pantothenic acid are mixed at low temperature (6-8°C) in a dry environment to obtain the product.

The present invention adopts Lemon balm, winter vanilla, thyme, cinnamon and other substances to obtain its plant essential oil through steam distillation, chemical extrusion, extractant refining, etc., and then purifies thymol and cinnamaldehyde; uses dextrin powder as Carrier, prepared under low temperature and dry environment-compound plant essential oil (thymol: cinnamaldehyde: dextrin powder, 9:27:164), can also be purchased directly from the market.

The invention also provides the use of the composition in preparing feed additives for improving body condition or production performance of sows after delivery.

In the present invention, the additive is added to the rations of sows in the gestational period from 96 days to the delivery stage and sows in the lactation stage; the plant essential oil thymol, plant essential oil cinnamaldehyde, L-lysine, vitamin A, folic acid, pantothenic acid and carrier Calcium carbonate and dextrin powder are scientifically compounded in strict accordance with the dosage of each component, and finally added to the diet of sows, which effectively increases the content of immunoglobulins in the lactating sows, increases the feed intake of lactating sows, and improves the sows' diet to a certain extent. The body condition of pigs reduces the loss of lactation and increases the number of healthy piglets at birth; on the other hand, the additive combination can affect breast milk, increase the content of immunoglobulin in milk and the content of milk fat and non-fat solids in milk during and after lactation , to better protect the health of suckling piglets and improve the weaning survival of piglets; since this type of additive combination is a non-toxic and harmless product, it is absorbed by the animal body, and its metabolites are excreted from the body without any harm to the environment; this type of composition When used in farming, it can alleviate the pressure on the environment caused by the use of antibiotics and benefit farming.

The feed additive of the present invention can effectively improve the body condition of the sow after delivery, restore the health of the mother, improve the immunity of the sow, and at the same time improve the breast milk, ensure the health of the piglet, and increase the weaning survival; in addition, the use of this type of additive can alleviate the environmental impact caused by the use of antibiotics. The pressure brought by it will bring benefits to the pig industry.

detailed description

The preparation method of embodiment 1 feed additive of the present invention

Thymol and cinnamaldehyde in an additive composition for improving the body condition and production performance of sows are plant-based aromatic compounds. The processing and production processes are all carried out by Chengdu Hualuo Biotechnology Co., Ltd., and dextrin powder is used as the The carrier is prepared in a low-temperature environment and a dry environment, and the ratio of the three is 9:27:164; the obtained compound essential oil is then mixed with pre-prepared L-lysine, threonine, vitamin A, folic acid, pantothenic acid, and carrier carbonic acid The mixture of calcium is strictly compounded according to the dosage: the late pregnancy (pregnancy 96d ~ childbirth) and breast-feeding period respectively add the composition components (100 parts): 1.8 parts of plant essential oil thymol, 5.4 parts of plant essential oil cinnamaldehyde, L- 7.5 parts of lysine, 5.2 parts of threonine, 3.5 parts of vitamin A, 0.5 parts of folic acid, 3.75 parts of pantothenic acid, and the rest are carriers. The carrier is composed of stone powder and dextrin powder in a ratio of 1:4. screen.

The addition amount of the product of the present invention in late pregnancy and lactation sow feed is 1200 g/ton.

The preparation of embodiment 2 feed additives of the present invention

The feed additive was prepared according to the method of Example 1, and the composition of the additive composition was: 1 part of thymol, 4 parts of cinnamaldehyde, 6 parts of L-lysine, 4 parts of threonine, 3 parts of vitamin A, 0.4 part of folic acid, and 3 parts of pantothenic acid.

The preparation of embodiment 3 feed additives of the present invention

Prepare the feed additive according to the method of Example 1, and the composition of the additive composition is: 2 parts of thymol, 6 parts of cinnamaldehyde, 8 parts of L-lysine, 6 parts of threonine, 4 parts of vitamin A, 0.6 part of folic acid, 4 parts of pantothenic acid share.

Prove the beneficial effect of the present invention below by clinical test.

In order to verify the feeding effect of the present invention on breeding sows, select 120 pregnant sows whose body condition is close to and healthy at Sichuan Blue Goose Collective National Collection Animal Husbandry and Breeding Demonstration Base, and are randomly divided into 2 treatment groups (i.e. control group, treatment group). Group), each processing 60 repetitions, the treatment group uses the feed prepared in Example 1; from its 96 days of gestation to the weaning of piglets on 21d, investigate the production performance of sows in each treatment group, the immunoglobulin in the mother's body and milk level and content of conventional milk nutrients.

The test results are as follows:

1. The combination of additives to improve the body condition and production performance of sows. The effect is shown in Table 1 below. To a certain extent, the number of live piglets and healthy piglets of sows was increased, and the stillbirth rate and mummy rate of piglets were reduced (71.43. %, 50.00%); in addition, the addition of this type of composition increases the daily feed intake of sows, significantly reduces the lactation loss of sows (P<0.05), and improves the weaning survival rate of piglets.

Table 1 Effect of additive combination on sow performance

Note: * indicates P<0.05

2. The combination of additives to improve the body condition and production performance of sows. The effects are shown in Table 2 below. Adding this type of composition can effectively increase the serum IgA level of sows throughout the lactation period, thereby ensuring the health of sows after delivery.

The influence of table 2 additive combination on sow serum immunoglobulin (n=6, ug/ml)

Note: * indicates P<0.05

3. It also has a significant impact on the milk components of lactating sows, as shown in Table 3: adding this type of composition significantly improves the concentration of immunoglobulin IgG in colostrum and normal milk, significantly improves the IgM level in milk on the 14th day after delivery, and It has the effect of increasing the concentration of milk fat and non-fat solids in the middle and late stages of lactation; these are beneficial to promoting the growth and development of lactating piglets, and are beneficial to improving the weaning survival of piglets.

The influence of table 3 additive combination on sow milk composition (n=6, ug/ml)

Note: * indicates P<0.05

Experiments have proved that two kinds of plant essential oils with strong antibacterial activity discovered so far are used instead of antibiotics on breeding sows. Calcium carbonate and dextrin powder are used as carriers, combined with a certain amount of lysine, vitamin A, folic acid, and pantothenic acid. Developed a natural, safe, high-efficiency feed additive combination that can improve the body condition of sows after delivery, improve the reproductive performance of sows, and at the same time affect the active ingredients of breast milk, better protect the health of suckling piglets, and increase the survival of weaning; this type of product To a certain extent, it also plays a role in relieving the pressure of antibiotic use in farming, and brings benefits to the pig breeding industry to increase income.

Claims (9)

1. An additive composition capable of improving body condition or production performance of sows after childbirth, characterized in that: it is composed of the following raw materials in weight ratio: 1-2 parts of thymol, 4-6 parts of cinnamaldehyde, 11-13 parts of amino acids, 6-8 parts of vitamins. 2. The composition according to claim 1, characterized in that: the amino acid is one or a mixture of L-lysine and threonine; the vitamins are vitamin A, folic acid, pantothenic acid one or a mixture of two or more. 3. The composition according to claim 2, characterized in that: it is made up of the following raw materials in weight ratio: 1-2 parts of thymol, 4-6 parts of cinnamaldehyde, 6-8 parts of L-lysine, 4-6 parts of threonine, 3-4 parts of vitamin A, 0.4-0.6 parts of folic acid, 3-4 parts of pantothenic acid. 4. composition according to claim 3 is characterized in that: it is made up of the raw material of following weight ratio: Thymol 1.8 parts, cinnamaldehyde 5.4 parts, L-lysine 7.5 parts, threonine 5.2 parts, vitamin A 3.5 parts, folic acid 0.5 parts, pantothenic acid 3.75 parts. 5. The composition according to any one of claims 1-4, characterized in that there is a carrier in the raw materials, which is composed of stone powder and dextrin powder at a ratio of 1:3-5. 6. The composition according to claim 5, characterized in that: the carrier is composed of stone powder and dextrin powder in a ratio of 1:4. 7. The composition according to claim 5 or 6, characterized in that: the carrier is crushed through a 40-mesh sieve. 8. A preparation method for the composition of any one of claims 1-7, comprising the steps of: Take thymol, cinnamaldehyde, L-lysine, threonine, vitamin A, folic acid, and pantothenic acid, and mix them at a low temperature of 6-8°C in a dry environment to obtain the product. 9. Use of the composition according to any one of claims 1-7 in the preparation of feed additives for improving body condition or production performance of sows after parturition.