CN107648061A - A kind of shampoo with anti-dandruff nourishing pearly-lustre and preparation method thereof - Google Patents

Abstract

A shampoo with anti-dandruff nourishing pearl consists of: N-fatty acyl-L-glycinate 10-25%, alcohol ether glycoside 5-15%, fatty alcohol polyoxyethylene ether 2-5%, coconut Oleamidopropyl Betaine 1‑5%, Sodium Fatty Alcohol Polyoxyethylene Ether Carboxylate 1‑3%, C16‑18 Alcohol 0.5‑1.5%, Squalane 0.3‑3%, Amino Acid 1‑1.5%, Cationic Conditioning Agent 0.05‑0.8%, the balance of deionized water. The invention has the advantages of no silicone oil, no stimulation, anti-dandruff, nourishment and pearl luster.

Description

A kind of shampoo with anti-dandruff nourishing pearl and its preparation method

technical field

The invention belongs to a shampoo, in particular to a shampoo with anti-dandruff nourishing pearl and a preparation method thereof.

Background technique

Silicone-free shampoo has become a popular trend in the shampoo industry today. However, many silicone-free shampoos on the market simply remove silicone oil, resulting in a reduction in the conditioning performance of the shampoo, which is a degradation of technology. The real silicone oil-free shampoo is obtained from shampoos with mild surfactants, special oils and effective scalp care ingredients through silicone oil-free technology, and its core function is to care for the scalp. Silicone-free cleansing and care products should be mild in performance, easy to clean after use, and have the same effect on smoothing hair as products containing silicone oil. Most importantly, they should also have the function of caring for the scalp.

N-fatty acyl amino acid surfactants have low irritation, low toxicity, mildness, strong antibacterial and decontamination capabilities, coupled with rich and delicate foaming properties and excellent compatibility, they have become the new darling of the daily chemical industry. It is the first choice for mild surfactants in silicone oil-free shampoos, but it has not been widely used due to problems such as difficult thickening and poor conditioning during application.

The main causes of dandruff are sebum, fungi and individual susceptibility. Starting from the cause, most anti-dandruff products on the market have added anti-dandruff agents that inhibit fungi in shampoos. These anti-dandruff agents have certain irritation and toxicity, and do not meet the current concept of safety and green. From the perspective of sebum, choosing a natural and non-irritating balanced oil shampoo can become a major research idea for anti-dandruff and anti-itching.

Squalane can strengthen the repair of epidermis and balance oil; it has strong affinity and can integrate with human sebum membrane to form a natural barrier on the skin surface; it can inhibit the peroxidation of skin lipids and effectively penetrate into the skin , and promote the proliferation of skin basal cells; can open skin pores, promote blood microcirculation, enhance cell metabolism, help repair damaged cells; can inhibit the growth of mold. The advantages of squalane are in line with the concept of combining scalp care with anti-dandruff nourishment, and it is one of the best candidates to replace traditional silicone oil. However, the current application of squalane is more common in creams or facial cleansers.

The patent application number is 201610536892.6, an amino acid silicone oil-free shampoo, which discloses an amino acid silicone oil-free shampoo, which contains an amino acid surfactant; the amino acid surfactant is the main active ingredient; the amino acid silicone oil-free shampoo Also contains water, humectants, conditioners and preservatives. In the embodiment, other surfactants and water-soluble oil components are added. The defect of this kind of formula is: 1. The anti-dandruff ingredient is not involved in the formula of this comparative document, and the anti-dandruff effect is not great; It will be washed away with the water flow, it is not easy to adhere to the hair tip and scalp, and the effect of nursing the scalp is not obvious; 3. Pearlescent agent and thickener must be added to the formulas of the examples in this comparative document, which cannot really achieve environmental protection and mild performance. Purpose.

The patent application number is 201610586803.9, a shampoo containing amino acid surfactant and its preparation method. In the shampoo of this invention, amino acid surfactant is used as the main surfactant, and amino acid surfactant is added in the preparation process of amino acid surfactant shampoo. One or more small molecule alcohols are added to increase the solubility of lipid amino acids in surfactants, but viscosity regulators are still used in the examples, indicating that the problem of amino acid thickening has not been fundamentally solved.

Contents of the invention

The object of the present invention is to provide a silicone-free, non-irritating shampoo with anti-dandruff nourishing pearl and a preparation method thereof.

In the shampoo of the present invention, N-fatty acyl amino acid surfactants and alcohol ether glycosides are used as the main surfactants, and are compatible with mild surfactants such as alcohol ether carboxylates and cocamidopropyl betaine, and amino acids are used as acid Alkali conditioner, together with squalane, which has the effect of balancing oil and nourishing care, makes the product mild and non-irritating, with good cleaning power, combability, anti-dandruff ability and viscosity, and has a pearlescent effect.

The object of the present invention is achieved by the following methods:

A shampoo with anti-dandruff nourishing pearl, characterized in that the mass percentage of the shampoo consists of:

N-fatty acyl-L-glycine salt in the above-mentioned invention is the compound with following general formula:

Among them: R is the alkyl group of a saturated or unsaturated, straight-chain or branched-chain fatty acid with 8-18 carbon atoms; M is K or Na. N-fatty acyl-L-glycine salt preferably sodium N-lauroyl-L-glycinate, potassium N-lauroyl-L-glycinate, sodium N-cocoyl-L-glycine or N-cocoyl-L-glycine potassium.

The alcohol ether glycoside in the above-mentioned invention is the compound with following general formula:

Wherein: R is an alkyl group with 8-18 carbon atoms, m is 1.2-1.8, and n is 1-3. The alcohol ether glycoside is preferably C _12-14 alcohol ether glycoside (m=1.2, n=2) or C _16-18 alcohol ether glycoside (n=3, m=1.8).

Fatty alcohol polyoxyethylene ether in the above-mentioned invention is the compound with following general formula:

R-(OCH ₂ CH ₂ ) _n OH

Wherein R is an alkyl group with 8-18 carbon atoms, and n is 3-9. Fatty alcohol polyoxyethylene ether is preferably C _12-14 fatty alcohol polyoxyethylene ether (n=9), C _16-18 fatty alcohol polyoxyethylene ether (n=7) or selected C _12-14 fatty alcohol polyoxyethylene ether (n=5)

Fatty alcohol polyoxyethylene ether sodium carboxylate in the above-mentioned invention is the compound with following general formula:

R-(OCH ₂ CH ₂ ) _n OCH ₂ COONa

Wherein R is an alkyl group with 8-18 carbon atoms, and n is 3-9. Sodium fatty alcohol polyoxyethylene ether carboxylate, preferably C _12-14 sodium fatty alcohol polyoxyethylene ether carboxylate (n=9), or C _16-18 sodium fatty alcohol polyoxyethylene ether carboxylate (n=7)

The amino acid in the above invention refers to one or more of glycine, glutamic acid, sarcosine and lysine.

The cationic conditioner in the above invention refers to one of hydroxypropyl guar trimethylammonium chloride, polyquaternium-10, SC-60, and JR-400.

The pH of the shampoo in the above invention is 6.5-7.0

The viscosity of the shampoo in the above invention is 2500-4000cP

The preparation method of shampoo of the present invention, comprises the steps:

(1) According to the shampoo composition, mix squalane, C _16-18 alcohol, alcohol ether glycoside and fatty alcohol polyoxyethylene ether and heat it to 50-80°C, preferably 60-70°C, and stir while heating to obtain A Mutually;

(2) According to the shampoo composition, mix N-fatty acyl-L-glycine salt, cocamidopropyl betaine, sodium fatty alcohol polyoxyethylene ether carboxylate, amino acid and deionized water and heat to 50-80°C, Preferably at 60-70°C, stir while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools down to below 40°C, then add cationic conditioner and mix evenly to obtain the product.

Compared with existing inventions, the present invention has the following advantages:

1. Squalane, which is close to human skin, is used to replace traditional silicone oil, which can give silicone-free shampoo new moisturizing, scalp care, oil balancing and anti-dandruff effects;

2. Select the natural non-irritating N-fatty acyl-L-glycine salt and alcohol ether glycoside as the main surfactant, so that the shampoo has the advantages of low irritation and fine foam, and at the same time makes the hair smooth and smooth after washing. Good fullness;

3. Select fatty alcohol polyoxyethylene ether, cocamidopropyl betaine and sodium fatty alcohol polyoxyethylene ether carboxylate as co-surfactants, and compound them with the main surfactant in a certain proportion to prepare the shampoo Good viscosity, which solves the thickening problem of amino acid shampoo;

4. Amino acid is selected as the acid-base regulator, and in this formula, it is compatible with other ingredients, and the prepared shampoo has a special pearlescent effect.

Detailed ways

Embodiment 1: each material weight percentage is as follows:

The shampoo is prepared as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2), C _12-14 fatty alcohol polyoxyethylene ether (n=9 ) mixed and heated to 60°C, and stirred while heating to obtain phase A;

(2) According to the shampoo composition, N-lauroyl-L-glycinate sodium, cocamidopropyl betaine, C _16-18 fatty alcohol polyoxyethylene ether carboxylate sodium (n=7), glutamic acid, Glycine and deionized water are mixed and heated to 60°C, and stirred while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools below 40°C, then add JR400 and mix well to obtain the product.

Embodiment 2: each material weight percentage is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _16-18 alcohol ether glycoside (n=3, m=1.8) and C _12-14 fatty alcohol polyoxyethylene ether (n=5 ) mixed and heated to 65°C, and stirred while heating to obtain Phase A;

(2) According to the shampoo composition, N-lauroyl-L-glycinate potassium, cocamidopropyl betaine, C _12-14 fatty alcohol polyoxyethylene ether carboxylate sodium (n=9), glycine, glutamine Mix acid and deionized water and heat to 65°C, stir while heating to obtain phase B;

(3) Add phase B into phase A, and keep stirring. After cooling to below 40°C, add polyquaternium-10, and mix well to obtain the product.

Embodiment 3: each material weight percentage is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2) and C _12-14 fatty alcohol polyoxyethylene ether (n=5 ) mixed and heated to 50°C, and stirred while heating to obtain phase A;

(2) According to the shampoo composition, N-cocoyl-L-glycinate potassium, cocamidopropyl betaine, C _16-18 fatty alcohol polyoxyethylene ether carboxylate sodium (n=7), sarcosine Mix with deionized water and heat to 80°C, stir while heating to obtain phase B;

(3) Add phase B into phase A, and keep stirring. After cooling to below 40°C, add hydroxypropyl guar trimethylammonium chloride, and mix well to obtain the product.

Embodiment 4: each material weight percentage is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2) and C _16-18 fatty alcohol polyoxyethylene ether (n=7 ) mixed and heated to 80°C, and stirred while heating to obtain phase A;

(2) According to the composition of shampoo, N-cocoyl-L-glycinate sodium, cocamidopropyl betaine, C _16-18 fatty alcohol polyoxyethylene ether carboxylate sodium (n=7), lysine Mix with deionized water and heat to 80°C, stir while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools below 40°C, add SC-60 and mix well to obtain the product.

Embodiment 5: each material weight percent is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2) and C _12-14 fatty alcohol polyoxyethylene ether (n=5 ) mixed and heated to 70°C, and stirred while heating to obtain phase A;

(2) According to the shampoo composition, N-cocoyl-L-glycinate potassium, cocamidopropyl betaine, C _12-14 fatty alcohol polyoxyethylene ether carboxylate sodium (n=9), sarcosine , glutamic acid and deionized water are mixed and heated to 70°C, and stirred while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools down to below 40°C, then add cationic conditioner and mix evenly to obtain the product.

Comparative example 1: the weight percentages of each material are as follows:

The shampoo is prepared as follows:

(1) According to the composition of shampoo, mix and heat C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2), C _12-14 fatty alcohol polyoxyethylene ether (n=9) to 60°C, stirring while heating to obtain phase A;

(2) According to the shampoo composition, N-lauroyl-L-glycinate sodium, cocamidopropyl betaine, C _16-18 fatty alcohol polyoxyethylene ether carboxylate sodium (n=7), glutamic acid, Glycine and deionized water are mixed and heated to 60°C, and stirred while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools below 40°C, then add JR400 and mix well to obtain the product.

Compared with Example 1, Comparative Example 1 did not add squalane, and the prepared product had unsatisfactory anti-dandruff properties and smoothness.

Comparative example 2: the weight percentages of each material are as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of shampoo, squalane, C _16-18 alcohol, C _12-14 alcohol ether glycoside (m=1.2, n=2) and C _16-18 fatty alcohol polyoxyethylene ether (n=7 ) mixed and heated to 80°C, and stirred while heating to obtain phase A;

(2) Composition by shampoo, N-cocoyl-L-sodium glycinate, cocamidopropyl betaine, C _16-18 fatty alcohol polyoxyethylene ether carboxylate sodium (n=7), citric acid and Deionized water is mixed and heated to 80°C, and stirred while heating to obtain phase B;

(3) Add phase B into phase A and keep stirring until it cools below 40°C, add SC-60 and mix well to obtain the product.

Compared with Example 2, the pH regulator used in Comparative Example 2 is citric acid, and the prepared product has no pearlescent effect.

Comparative example 3: the weight percentage of each material is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the composition of the shampoo, mix squalane, _C16-18 alcohol, and C12-14 fatty alcohol polyoxyethylene ether (n=5) and heat to 50°C, and stir while heating to obtain phase A;

(2) Composition by shampoo, N-cocoyl-L-glycinate potassium, cocamidopropyl betaine, C16-18 fatty alcohol polyoxyethylene ether carboxylate (n=7), sarcosine and Deionized water is mixed and heated to 80°C, and stirred while heating to obtain phase B;

(3) Add phase B into phase A, and keep stirring. After cooling to below 40°C, add hydroxypropyl guar trimethylammonium chloride, and mix well to obtain the product.

Compared with Example 3, Comparative Example 3 did not add fatty alcohol polyoxyethylene ether, and the product produced was not ideal.

Comparative example 4: the weight percentage of each material is as follows:

The preparation method of above-mentioned shampoo is as follows:

(1) According to the shampoo composition, mix squalane, _C16-18 alcohol and C12-14 alcohol ether glycoside (m=1.2, n=2) and heat to 50°C, stir while heating to obtain phase A;

(2) According to the shampoo composition, mix and heat N-cocoyl-L-glycinate potassium, cocamidopropyl betaine, sarcosine and deionized water to 80°C, and stir while heating to obtain phase B;

(3) Add phase B into phase A, and keep stirring. After cooling to below 40°C, add hydroxypropyl guar trimethylammonium chloride, and mix well to obtain the product.

Compared with Example 4, Comparative Example 4 did not add fatty alcohol polyoxyethylene ether and sodium fatty alcohol polyoxyethylene ether carboxylate, and the prepared product had an unsatisfactory viscosity.

Comparative example 5: the weight percentage of each material is as follows:

The preparation method of above-mentioned shampoo is as follows:

According to the composition of shampoo, squalane, C16-18 alcohol, C16-18 alcohol ether glycoside (n=3, m=1.8), C12-14 fatty alcohol polyoxyethylene ether (n=5), N-lauroyl - Potassium L-glycinate, cocamidopropyl betaine, sodium C12-14 fatty alcohol polyoxyethylene ether carboxylate (n=9), glycine, glutamic acid and deionized water are mixed and heated to 70 ° C, while heating Stir, wait until it cools below 40°C, add JR400, mix evenly, and get the product.

Compared with Example 5, the preparation method of Comparative Example 5 is different, and the prepared product is delaminated and unstable. Carry out experiment to embodiment and comparative example:

1. Irritation test method: Select 4 healthy white experimental rabbits, cut off the back hair on both sides of the experimental rabbits, and try to shave as clean as possible. The hair removal range is controlled at 3cm×3cm, and the smear area is 2.5cm×2.5cm. Take about 5g of the test substance, mix thoroughly with an appropriate amount of egg white, and evenly apply it on the depilated skin on the left side, and apply egg white on the right side as a control. Apply it once a day, keep it for 4 hours, and apply it continuously for 14 days. From the 2nd day, the hair was cut before each application, and the control area and the experimental area were treated in the same way. 4 hours after the test animals were coated, the control area and the experimental area were washed with warm 0.9% sodium chloride solution, and the experimental rabbits were allowed to bathe for 1 hour. The skin changes in the control area and the experimental area were observed with naked eyes. Calculate the highest score per day for each animal. The reaction results were evaluated by the skin irritation reaction intensity grading scale, and the results are shown in Table 1.

2. Evaluation method for anti-dandruff and smoothness of dry hair: The prepared shampoos described in Examples 3 and 5 and Comparative Example 1 were distributed to 100 volunteers aged 18-40 for testing. Among them, 50 male volunteers and 50 female volunteers washed their hair according to the same method when using the shampoo samples. Each shampoo was used for two consecutive weeks, and the shampoo was rated according to their own feelings, and the score was 5 points. 1 is the worst, 3 is moderate, 5 is the best, and the higher the score, the better the effect. The average score of various use effect evaluations.

3. Viscosity measurement method: refer to GB/T 5561-2012, and the experimental results are shown in Table 1.

4. Measuring method of PH value: refer to GB/T 6368-2008, the experimental results are shown in Table 1.

The test result of embodiment 1,2,3,4 and 5 and comparative example 1,2,3,4 and 5 gained shampoo is as follows

experiment number Exterior PH value viscosity Anti-dandruff dry hair smoothness irritant Example 1 milky white with pearl 6.7 3500 4.6 4.0 non-irritating Example 2 milky white with pearl 6.5 3000 4.7 4.1 non-irritating Example 3 milky white with pearl 6.6 3800 4.5 4.2 non-irritating Example 4 milky white with pearl 7.0 2600 4.4 4.5 non-irritating Example 5 milky white with pearl 6.8 4000 4.4 4.4 non-irritating Comparative example 1 milky white with pearl 6.6 3000 3.6 3.0 non-irritating Comparative example 2 milky white, no pearl ‐‐‐‐ ‐‐‐‐ ‐‐‐‐ ‐‐‐‐ ‐‐‐‐ Comparative example 3 milky white with pearl 6.9 1200 ‐‐‐‐ ‐‐‐‐ non-irritating Comparative example 4 milky white with pearl 6.5 1500 ‐‐‐‐ ‐‐‐‐ non-irritating Comparative example 5 layered ‐‐‐‐ ‐‐‐‐ ‐‐‐‐ ‐‐‐‐ ‐‐‐‐

As can be seen from Table 1, the prepared products are all non-irritating. In Comparative Example 1, squalane was not added, and the smoothness and dandruff removal of the prepared product were not good; in Comparative Example 2, citric acid was used instead of amino acids to adjust the pH value, and the prepared The product has no pearl effect; in comparative example 3 and comparative example 4, alcohol ether glycoside and alcohol ether, sodium alcohol ether carboxylate are not added respectively, the product viscosity prepared is not ideal; the preparation method of comparative example 5 and the preparation method of embodiment Different, the product prepared by combining other ingredients except the cationic conditioning agent is unstable and the delamination phenomenon is serious. Examples 1-5 are all within the scope of the present invention. The prepared products are mild and non-irritating, have good cleaning power, combability, dandruff removal ability and viscosity, and have a pearlescent effect, and have a good market prospect.

Claims (13)

1. a kind of shampoo with anti-dandruff nourishing pearly-lustre, it is characterised in that percentage by weight composition is as follows：

2. a kind of shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that N- fatty acyl groups-L- is sweet Propylhomoserin salt is the compound for having below formula：

Wherein：R be carbon number 8-18 saturations or unsaturation, straight or branched aliphatic acid alkyl；M is K or Na.

3. a kind of shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 2, it is characterised in that N- fatty acyl groups-L- is sweet Propylhomoserin salt is N- lauroyl-L- Sodium Glycinates, N- lauroyl-L- glycine potassium, N- cocoyl-L- Sodium Glycinates or N- Cocoyl-L- glycine potassium.

4. a kind of shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that alcohol ether glucoside is that have The compound of below formula：

Wherein：R is the alkyl that carbon number is 8-18, m 1.2-1.8, n 1-3.

A kind of 5. shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 4, it is characterised in that alcohol ether glucoside C_12-14 Alcohol ether glucoside or C_16-18Alcohol ether glucoside.

A kind of 6. shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that aliphatic alcohol polyethenoxy Ether is the compound for having below formula：

R-(OCH₂CH₂)_nOH

Wherein R is carbon number 8-18 alkyl, n 3-9.

A kind of 7. shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 6, it is characterised in that aliphatic alcohol polyethenoxy Ether AEO is C_12-14AEO, C_16-18AEO selects C_12-14Fatty alcohol APEO.

A kind of 8. shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that aliphatic alcohol polyethenoxy Ether carboxylic acid sodium is the compound for having below formula：

R-(OCH₂CH₂)_nOCH₂COONa

Wherein R is carbon number 8-18 alkyl, n 3-9.

A kind of 9. shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 8, it is characterised in that aliphatic alcohol polyethenoxy Ether carboxylic acid sodium is C_12-14AEO carboxylic acid sodium or C_16-18AEO carboxylic acid sodium.

10. a kind of shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that amino acid is sweet ammonia One or more in acid, glutamic acid, methyl amimoacetic acid, lysine.

11. a kind of shampoo with anti-dandruff nourishing pearly-lustre as claimed in claim 1, it is characterised in that cation opsonizing agent is One kind in hydroxypropyl guar gum trimethyl ammonium chloride, Polyquaternium-10, SC-60, JR-400.

A kind of 12. shampoo with anti-dandruff nourishing pearly-lustre as described in claim any one of 1-11, it is characterised in that hair washing The PH of water is 6.5-7.0, viscosity 2500-4000cP.

13. a kind of preparation method of shampoo with anti-dandruff nourishing pearly-lustre as described in claim any one of 1-12, it is special Sign is to comprise the following steps：

(1) formed by shampoo, by saualane, C_16-18Alcohol, alcohol ether glucoside and AEO Hybrid Heating are to 50-80 DEG C, preferably 60-70 DEG C, heat while stirring, obtain A phases；

(2) formed by shampoo, by N- fatty acyl group-L- glycinates, Cocoamidopropyl betaine, aliphatic alcohol polyethenoxy Ether carboxylic acid sodium, amino acid and deionized water Hybrid Heating preferably 60-70 DEG C, heat while stirring to 50-80 DEG C, obtain B phases；

(3) B is added in A phases, and is stirred continuously, be cooled to less than 40 DEG C, add cation opsonizing agent, be well mixed, Obtain product.