CN107233265A - Strong tooth bacteriostatic gel - Google Patents
Strong tooth bacteriostatic gel Download PDFInfo
- Publication number
- CN107233265A CN107233265A CN201710675968.8A CN201710675968A CN107233265A CN 107233265 A CN107233265 A CN 107233265A CN 201710675968 A CN201710675968 A CN 201710675968A CN 107233265 A CN107233265 A CN 107233265A
- Authority
- CN
- China
- Prior art keywords
- parts
- extract
- raw material
- menthol
- bacteriostatic gel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K8/04—Dispersions; Emulsions
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：300 400 parts of Angelica Dahurica extract, 300 400 parts of thyme extract, 200 300 parts of Honegsukle flower P.E, 200 300 parts of Tea Polyphenols, 100 200 parts of menthol, 100 200 parts of licorice, 100 200 parts of notoginseng extract, 50 100 parts of xylitol, water 800 1500.The raw materials used present invention is integration of drinking and medicinal herbs material, and its property of medicine is gentle, has no toxic side effect, a variety of crude drug reasonable compatibility enhancing antibacterials, anti-inflammatory, analgesic, effect of deodorization, various raw material compounding uses, cooperative compensating, it is ensured that security, the validity used.
Description
Technical field
The present invention relates to field of oral care, specifically, it is related to a kind of strong tooth bacteriostatic gel.
Background technology
Common oral care implement is mainly toothpaste, mouthwash etc., its basic function be cleaning tooth, fresh breath,
Maintain oral hygiene.With the continuous improvement of people's living standards, functional requirements of the consumer for oral care implement
Constantly strengthening, it is therefore, various that there is anti-inflammatory, analgesia, hypo-allergenic, anti-caries oral care products to arise at the historic moment.However, existing
Some feature oral care implements with the addition of various chemical compositions and additive mostly, with certain toxic side effect, especially
For oral problem more serious consumer, it is easy to produce allergic reaction, or even aggravate illness, it would therefore be highly desirable to design one
Plant gentle, the evident in efficacy oral care product of drug effect.
The content of the invention
Based in place of the deficiencies in the prior art, the present invention provides strong tooth bacteriostatic gel, and its raw material gently has no side effect, rationally
Compatibility, which is integrated, improves sterilization analgesic effect.
The present invention is adopted the technical scheme that to achieve these goals：
Strong tooth bacteriostatic gel, it is characterised in that：In terms of parts by weight, including the following raw material component：Angelica Dahurica extract 300-
400 parts, 300-400 parts of thyme extract, 200-300 parts of Honegsukle flower P.E, 200-300 parts of Tea Polyphenols, menthol 100-
200 parts, 100-200 parts of licorice, 100-200 parts of notoginseng extract, 50-100 parts of xylitol, water 800-1500.
Preferably, tooth bacteriostatic gel is good for, in terms of parts by weight, including the following raw material component：Angelica Dahurica extract 350-380
Part, 350-380 parts of thyme extract, 230-260 parts of Honegsukle flower P.E, 230-260 parts of Tea Polyphenols, menthol 150-180
Part, 150-180 parts of licorice, 150-180 parts of notoginseng extract, 60-80 parts of xylitol, 1000-1300 parts of water.
Preferably, tooth bacteriostatic gel is good for, in terms of parts by weight, including the following raw material component：360 parts of Angelica Dahurica extract, hundred
In fragrant 360 parts of extract, 250 parts of Honegsukle flower P.E, 250 parts of Tea Polyphenols, 160 parts of menthol, 160 parts of licorice, field
Seven 160 parts of extracts, 70 parts of xylitol, 1200 parts of water.
Preferably, tooth bacteriostatic gel is good for, in terms of parts by weight, in addition to the following raw material component：1-2 parts of xanthans or OK a karaoke club
2-3 parts of glue.
The present invention is screened and verified repeatedly from existing integration of drinking and medicinal herbs material, gives full play to the synergy of each component,
Strong tooth bacteriostatic gel formula is obtained, wherein each raw material effect is as follows：
The root of Dahurain angelica is a kind of warm-natured, pungent medicinal and edible plant, and its extract is general molten by ethanol, ether etc. by the root of Dahurain angelica
Agent is extracted and formed, and contains the plurality of active ingredients such as Byakangelicol, Imperatorin, bergapten, phellopterin.Wherein, work as in vain
Return brain that there is anti-inflammatory, analgesia, the pharmacological activity of resisting pathogenic microbes；There is Imperatorin a variety of antibacterial activities and antiallergy to live
Property；Bergapten has functions that anti-inflammatory and antalgic；Phellopterin has antimycotic activity.
Thyme is to contain Thymol, carvacrol, linalool and O- in a kind of pungent fragrant plant of taste, its extract
The multiple compounds such as cymene -5- alcohol.Wherein, Thymol has good bactericidal action.Carvacrol has antimycotic
Activity, and also there is the effect of spasmolysis；Toxin angelicotoxin in Angelica Dahurica extract also containing a certain amount of cause spasm, therefore,
Thyme extract and Angelica Dahurica extract compounding use can be alleviated into the toxicity of angelicotoxin, it is ensured that the security used.Fragrant camphor tree
Alcohol has antibacterial activity to microorganisms such as Escherichia coli, staphylococcus aureuses, and can be combined with material frowzy, effectively clear
New implication；In addition, linalool can effectively suppress hammer mutant bacteria, it is to generate dental plaque after dextran by sucrose inversion to prevent it.
O- cymene -5- alcohol has stronger resist to oral microorganisms such as Pseudomonas aeruginosa, actinobacillus actinomycetem comitans, porphyromonas gingivalis
Bacterium activity.
Chlorogenic acid and galuteolin are mainly contained in Honegsukle flower P.E, to streptococcus, staphylococcus, Escherichia coli, green
The microorganisms such as purulence bacillus, companion unwrapping wire haemophilic bacterium have stronger bacteriostasis, are matched somebody with somebody with Angelica Dahurica extract, thyme extract
5, antibacterial effect is more notable.
Tea Polyphenols is the general name of Polyphenols of Tea, including flavanol compound, anthocyanin class, flavonoids, flavonols
With the plurality of active ingredients such as phenolic acid class, with stronger antioxidation activity and bacteriostatic activity, and the peculiar smell in adsorbable oral cavity,
Enhancing deodouring effect is cooperateed with thyme extract.In addition, Tea Polyphenols can suppress glucose polymerisation enzymatic activity, and then and thyme
Extract cooperates with preventing decayed tooth permanent tooth.
Menthol carries refrigerant mint smell and taste, available for gum and periodontal soft tissue anti-inflammatory analgetic.
Licorice typically contains glycyrrhizin, glycyrrhizic acid, and liquiritin, flavonoids of Glycyrrhiza, rear curtain are than wingceltis element, thorn awns handle
The medicinal ingredients such as florigen, Quercetin, have effects that clearing heat and detoxicating, relieving spasm to stop pain；In addition, having spasmolysis together with thyme extract
Effect.
There is anti-inflammatory hemostasis, swelling and pain relieving containing abundant ginsenoside in notoginseng extract, with menthol, sweet
Careless extract compound use is better.
Xylitol can prevent carious tooth while gel mouthfeel is increased, reduce the generation of dental plaque.
Carragheen or xanthans can be used for the denseness of increase gel, promote gel forming.
In summary, it is integration of drinking and medicinal herbs material that the present invention is raw materials used, and its property of medicine is gentle, has no toxic side effect, Duo Zhongtian
Right medicinal material reasonable compatibility enhancing antibacterial, anti-inflammatory, analgesic, effect of deodorization, various raw material compounding uses, cooperative compensating, it is ensured that make
Security, validity.
Embodiment
The present invention is described in further detail with reference to embodiment：
Embodiment 1
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：400 parts of Angelica Dahurica extract, thyme is extracted
400 parts of thing, 300 parts of Honegsukle flower P.E, 300 parts of Tea Polyphenols, 200 parts of menthol, 200 parts of licorice, notoginseng extract
200 parts, 100 parts of xylitol, 800 parts of water.
Dry Angelica Dahurica extract, thyme extract, Honegsukle flower P.E, Tea Polyphenols, menthol, radix glycyrrhizae are taken during making
Extract, notoginseng extract and xylitol powder, weigh be well mixed in proportion, add water in mixed raw material, side
Side stirring is added, Weak Gels are formed.
Further, in order that the gel formed is more uniform, can suitably it be heated in whipping process.
The present invention can be applied directly to clear water after affected part or tooth-implanting, artificial tooth marginal gingiva, 1-3min and gargle when using；Or
Gel is soluble in water, containing gargling 1-3min；Or directly brushed teeth using the present invention.
Embodiment 2
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：350 parts of Angelica Dahurica extract, thyme is extracted
380 parts of thing, 230 parts of Honegsukle flower P.E, 260 parts of Tea Polyphenols, 180 parts of menthol, 150 parts of licorice, notoginseng extract
180 parts, 80 parts of xylitol, 1000 parts of water, 2-3 parts of carragheen.
Dry Angelica Dahurica extract, thyme extract, Honegsukle flower P.E, Tea Polyphenols, menthol, radix glycyrrhizae are taken during making
Extract, notoginseng extract and xylitol powder, weigh be well mixed in proportion, add water in mixed raw material, side
Add side to stir, heated after stirring, and add carragheen, continue to stir to formation finished gel.
Embodiment 3
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：360 parts of Angelica Dahurica extract, thyme is extracted
360 parts of thing, 250 parts of Honegsukle flower P.E, 250 parts of Tea Polyphenols, 160 parts of menthol, 160 parts of licorice, notoginseng extract
160 parts, 70 parts of xylitol, 1200 parts of water.
Dry Angelica Dahurica extract, thyme extract, Honegsukle flower P.E, Tea Polyphenols, menthol, radix glycyrrhizae are taken during making
Extract, notoginseng extract and xylitol powder, weigh be well mixed in proportion, add water in mixed raw material, side
Side stirring is added, Weak Gels are formed.
Further, in order that the gel formed is more uniform, can suitably it be heated in whipping process.
Embodiment 4
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：380 parts of Angelica Dahurica extract, thyme is extracted
350 parts of thing, 260 parts of Honegsukle flower P.E, 230 parts of Tea Polyphenols, 150 parts of menthol, 180 parts of licorice, notoginseng extract
150 parts, 60 parts of xylitol, 1300 parts of water, 1 part of xanthans.
Dry Angelica Dahurica extract, thyme extract, Honegsukle flower P.E, Tea Polyphenols, menthol, radix glycyrrhizae are taken during making
Extract, notoginseng extract and xylitol powder, weigh be well mixed in proportion, add water in mixed raw material, side
Add side to stir, heated after stirring, and add xanthans, continue to stir to formation finished gel.
Embodiment 5
Strong tooth bacteriostatic gel, in terms of parts by weight, including the following raw material component：300 parts of Angelica Dahurica extract, thyme is extracted
300 parts of thing, 200 parts of Honegsukle flower P.E, 200 parts of Tea Polyphenols, 100 parts of menthol, 100 parts of licorice, notoginseng extract
100 parts, 50 parts of xylitol, water 1500,2 parts of xanthans.
Dry Angelica Dahurica extract, thyme extract, Honegsukle flower P.E, Tea Polyphenols, menthol, radix glycyrrhizae are taken during making
Extract, notoginseng extract and xylitol powder, weigh be well mixed in proportion, add water in mixed raw material, side
Add side to stir, heated after stirring, and add xanthans, continue to stir to formation finished gel.
Antibacterial experiment is carried out to the strong tooth bacteriostatic gel in embodiment 1-5, included for examination strain：Escherichia coli, golden yellow
Staphylococcus, Pseudomonas aeruginosa, actinobacillus actinomycetem comitans, Candida albicans and porphyromonas gingivalis, specific experiment method are as follows：
(1) strong each 5mL of tooth bacteriostatic gel in Example 1-5, is injected separately into sterilized petri dishes, and make parallel control and
The blank control of gel is replaced with sterile saline.
(2) previously prepared each bacterium piece for trying strain is dipped in strong tooth bacteriostatic gel and sterile saline respectively
3min。
(3) bacterium piece is moved into test tube respectively, adds sterile saline, fully shaking.Vibration draws 1.0ml after mixing
Spread plate, is cultivated.
(4) counted after bacterium colony is grown, and calculate sterilizing rate.
Experimental result is as shown in table 1.
Table 1
As can be seen here, the present invention supplies examination bacterium to have good antibacterial effect to above-mentioned.
It the above is only the preferred embodiment of the present invention, protection scope of the present invention is not limited to reality shown in this article
Example is applied, all technical schemes belonged under thinking of the present invention belong to protection scope of the present invention.It should be pointed out that being led for this technology
For the those of ordinary skill in domain, equivalence replacement without departing from the principles of the present invention to each raw material of the invention and aid in into
The increase and decrease divided is all fallen within protection scope of the present invention and open scope.
Claims (4)
1. strong tooth bacteriostatic gel, it is characterised in that：In terms of parts by weight, including the following raw material component：Angelica Dahurica extract 300-400
Part, 300-400 parts of thyme extract, 200-300 parts of Honegsukle flower P.E, 200-300 parts of Tea Polyphenols, menthol 100-200
Part, 100-200 parts of licorice, 100-200 parts of notoginseng extract, 50-100 parts of xylitol, water 800-1500.
2. strong tooth bacteriostatic gel according to claim 1, it is characterised in that：In terms of parts by weight, including the following raw material group
Point：350-380 parts of Angelica Dahurica extract, 350-380 parts of thyme extract, 230-260 parts of Honegsukle flower P.E, Tea Polyphenols 230-
260 parts, 150-180 parts of menthol, 150-180 parts of licorice, 150-180 parts of notoginseng extract, 60-80 parts of xylitol,
1000-1300 parts of water.
3. strong tooth bacteriostatic gel according to claim 1, it is characterised in that：In terms of parts by weight, including the following raw material group
Point：360 parts of Angelica Dahurica extract, 360 parts of thyme extract, 250 parts of Honegsukle flower P.E, 250 parts of Tea Polyphenols, menthol 160
Part, 160 parts of licorice, 160 parts of notoginseng extract, 70 parts of xylitol, 1200 parts of water.
4. the strong tooth bacteriostatic gel according to any one in claim 1-3, it is characterised in that：In terms of parts by weight, also
Including the following raw material component：2-3 parts of 1-2 parts of xanthans or carragheen.
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| CN201710675968.8A CN107233265A (en) | 2017-08-09 | 2017-08-09 | Strong tooth bacteriostatic gel |
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| CN201710675968.8A CN107233265A (en) | 2017-08-09 | 2017-08-09 | Strong tooth bacteriostatic gel |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108542973A (en) * | 2018-04-03 | 2018-09-18 | 金华市飞凌生物科技有限公司 | A kind of preparation method of antibacterial strong tooth extract |
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Application publication date: 20171010 |