CN106729304B - A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof - Google Patents
A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof Download PDFInfo
- Publication number
- CN106729304B CN106729304B CN201611115616.9A CN201611115616A CN106729304B CN 106729304 B CN106729304 B CN 106729304B CN 201611115616 A CN201611115616 A CN 201611115616A CN 106729304 B CN106729304 B CN 106729304B
- Authority
- CN
- China
- Prior art keywords
- chinese
- fasting
- sealwort
- fruit
- jujube
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003814 drug Substances 0.000 title claims abstract description 56
- 238000007086 side reaction Methods 0.000 title claims abstract description 14
- 238000002360 preparation method Methods 0.000 title abstract description 17
- 230000000116 mitigating effect Effects 0.000 title abstract description 6
- 235000001916 dieting Nutrition 0.000 title abstract description 4
- 230000037228 dieting effect Effects 0.000 title abstract description 4
- 244000241872 Lycium chinense Species 0.000 claims abstract description 22
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 22
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 22
- 241000522254 Cassia Species 0.000 claims abstract description 21
- 240000001008 Dimocarpus longan Species 0.000 claims abstract description 21
- 235000000235 Euphoria longan Nutrition 0.000 claims abstract description 21
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 21
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 21
- 235000008434 ginseng Nutrition 0.000 claims abstract description 21
- 240000008669 Hedera helix Species 0.000 claims abstract description 20
- 210000000582 semen Anatomy 0.000 claims abstract description 20
- 240000002505 Pogostemon cablin Species 0.000 claims abstract description 19
- 235000011751 Pogostemon cablin Nutrition 0.000 claims abstract description 19
- 244000126002 Ziziphus vulgaris Species 0.000 claims abstract description 7
- 229940126678 chinese medicines Drugs 0.000 claims abstract 2
- 235000005911 diet Nutrition 0.000 claims description 8
- 230000037213 diet Effects 0.000 claims description 8
- 239000000126 substance Substances 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000000843 powder Substances 0.000 claims description 5
- 239000002775 capsule Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 3
- 241000202807 Glycyrrhiza Species 0.000 claims description 2
- 241000208340 Araliaceae Species 0.000 claims 5
- 239000003826 tablet Substances 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 19
- 235000003642 hunger Nutrition 0.000 abstract description 14
- 230000008569 process Effects 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 10
- 238000009472 formulation Methods 0.000 abstract description 3
- 239000000203 mixture Substances 0.000 abstract description 3
- 230000037351 starvation Effects 0.000 abstract description 3
- 230000008859 change Effects 0.000 abstract description 2
- 231100000956 nontoxicity Toxicity 0.000 abstract description 2
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 description 20
- 240000004371 Panax ginseng Species 0.000 description 15
- 241001247821 Ziziphus Species 0.000 description 14
- 239000000796 flavoring agent Substances 0.000 description 12
- 235000019634 flavors Nutrition 0.000 description 12
- 208000024891 symptom Diseases 0.000 description 12
- 206010062717 Increased upper airway secretion Diseases 0.000 description 11
- 208000026435 phlegm Diseases 0.000 description 11
- 235000009508 confectionery Nutrition 0.000 description 9
- 206010012601 diabetes mellitus Diseases 0.000 description 8
- 235000013305 food Nutrition 0.000 description 8
- 206010033307 Overweight Diseases 0.000 description 7
- 206010016256 fatigue Diseases 0.000 description 7
- 230000036541 health Effects 0.000 description 7
- 206010063659 Aversion Diseases 0.000 description 6
- 230000008901 benefit Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 235000013339 cereals Nutrition 0.000 description 6
- 210000000952 spleen Anatomy 0.000 description 6
- 239000000341 volatile oil Substances 0.000 description 6
- 208000008589 Obesity Diseases 0.000 description 5
- 238000007796 conventional method Methods 0.000 description 5
- 208000002173 dizziness Diseases 0.000 description 5
- 235000020824 obesity Nutrition 0.000 description 5
- 239000002994 raw material Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 241000372132 Hydrometridae Species 0.000 description 4
- 230000003247 decreasing effect Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 230000008030 elimination Effects 0.000 description 4
- 238000003379 elimination reaction Methods 0.000 description 4
- 206010067484 Adverse reaction Diseases 0.000 description 3
- 208000004930 Fatty Liver Diseases 0.000 description 3
- 206010019708 Hepatic steatosis Diseases 0.000 description 3
- 208000001145 Metabolic Syndrome Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 241001116757 Pyrrosia lingua Species 0.000 description 3
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 description 3
- 230000006838 adverse reaction Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 208000010706 fatty liver disease Diseases 0.000 description 3
- 230000002218 hypoglycaemic effect Effects 0.000 description 3
- 230000003907 kidney function Effects 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 208000024794 sputum Diseases 0.000 description 3
- 210000003802 sputum Anatomy 0.000 description 3
- 231100000240 steatosis hepatitis Toxicity 0.000 description 3
- 235000019640 taste Nutrition 0.000 description 3
- 238000010792 warming Methods 0.000 description 3
- 240000004510 Agastache rugosa Species 0.000 description 2
- 208000001380 Diabetic Ketoacidosis Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 208000013016 Hypoglycemia Diseases 0.000 description 2
- 208000017170 Lipid metabolism disease Diseases 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 102000003929 Transaminases Human genes 0.000 description 2
- 108090000340 Transaminases Proteins 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 239000006071 cream Substances 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000001914 filtration Methods 0.000 description 2
- 206010022000 influenza Diseases 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 150000002632 lipids Chemical class 0.000 description 2
- 210000004185 liver Anatomy 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 235000020852 very low calorie diet Nutrition 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 244000205574 Acorus calamus Species 0.000 description 1
- 244000144725 Amygdalus communis Species 0.000 description 1
- 235000011437 Amygdalus communis Nutrition 0.000 description 1
- 235000001405 Artemisia annua Nutrition 0.000 description 1
- 240000000011 Artemisia annua Species 0.000 description 1
- 244000003416 Asparagus officinalis Species 0.000 description 1
- 235000005340 Asparagus officinalis Nutrition 0.000 description 1
- 235000011996 Calamus deerratus Nutrition 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 206010007134 Candida infections Diseases 0.000 description 1
- 240000008574 Capsicum frutescens Species 0.000 description 1
- 241000218645 Cedrus Species 0.000 description 1
- 235000007516 Chrysanthemum Nutrition 0.000 description 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- 241000721047 Danaus plexippus Species 0.000 description 1
- 206010012669 Diabetic hyperosmolar coma Diseases 0.000 description 1
- 235000002722 Dioscorea batatas Nutrition 0.000 description 1
- 235000006536 Dioscorea esculenta Nutrition 0.000 description 1
- 240000001811 Dioscorea oppositifolia Species 0.000 description 1
- 235000003416 Dioscorea oppositifolia Nutrition 0.000 description 1
- 208000032928 Dyslipidaemia Diseases 0.000 description 1
- 108010061435 Enalapril Proteins 0.000 description 1
- 208000007530 Essential hypertension Diseases 0.000 description 1
- 208000023661 Haematological disease Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- 206010027304 Menopausal symptoms Diseases 0.000 description 1
- 240000002948 Ophiopogon intermedius Species 0.000 description 1
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
- 235000011613 Pinus brutia Nutrition 0.000 description 1
- 241000018646 Pinus brutia Species 0.000 description 1
- 244000197580 Poria cocos Species 0.000 description 1
- 235000008599 Poria cocos Nutrition 0.000 description 1
- 244000046095 Psophocarpus tetragonolobus Species 0.000 description 1
- 235000010580 Psophocarpus tetragonolobus Nutrition 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 241000405414 Rehmannia Species 0.000 description 1
- 240000001341 Reynoutria japonica Species 0.000 description 1
- 235000018167 Reynoutria japonica Nutrition 0.000 description 1
- 206010039085 Rhinitis allergic Diseases 0.000 description 1
- 201000004239 Secondary hypertension Diseases 0.000 description 1
- 208000005392 Spasm Diseases 0.000 description 1
- 208000000491 Tendinopathy Diseases 0.000 description 1
- 208000023835 Tendon disease Diseases 0.000 description 1
- 102000009618 Transforming Growth Factors Human genes 0.000 description 1
- 108010009583 Transforming Growth Factors Proteins 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 208000036981 active tuberculosis Diseases 0.000 description 1
- 210000000577 adipose tissue Anatomy 0.000 description 1
- 208000026935 allergic disease Diseases 0.000 description 1
- 201000010105 allergic rhinitis Diseases 0.000 description 1
- 230000007815 allergy Effects 0.000 description 1
- 235000020224 almond Nutrition 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000004900 autophagic degradation Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 206010006451 bronchitis Diseases 0.000 description 1
- 230000001914 calming effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 201000003984 candidiasis Diseases 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 230000003920 cognitive function Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000001723 curing Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 235000018823 dietary intake Nutrition 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- GBXSMTUPTTWBMN-XIRDDKMYSA-N enalapril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(O)=O)CC1=CC=CC=C1 GBXSMTUPTTWBMN-XIRDDKMYSA-N 0.000 description 1
- 229960000873 enalapril Drugs 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- -1 honeyed bolus Substances 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 208000002551 irritable bowel syndrome Diseases 0.000 description 1
- 208000018937 joint inflammation Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000014571 nuts Nutrition 0.000 description 1
- 201000008482 osteoarthritis Diseases 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 238000011127 radiochemotherapy Methods 0.000 description 1
- 230000001172 regenerating effect Effects 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 201000002859 sleep apnea Diseases 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 210000000130 stem cell Anatomy 0.000 description 1
- 230000002459 sustained effect Effects 0.000 description 1
- 230000009747 swallowing Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 201000008827 tuberculosis Diseases 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8969—Polygonatum (Solomon's seal)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention provides a kind of Chinese medicines for mitigating fasting or side reaction of dieting and preparation method thereof.Said preparation ingredient is ginseng, the fruit of Chinese wolfberry, arillus longan, Semen Lablab Album, jujube, Chinese cassia tree, fructus amomi, dried orange peel, Pogostemon cablin, sealwort, Radix Glycyrrhizae.Full side links closely the interpretation of the cause, onset and process of an illness variation under fasting state, all medicine reasonable compatibilities, gather altogether Wen Yang, tonifying Qi, change turbid, replenishing essence work(.Receive hunger and other side reactions that the crowd of fasting is likely to occur in the fasted state for mitigating.Preliminary clinical test shows inventive formulation definite effect, and effect is rapid, no toxicity, can receive the ability and compliance of the resistance to starvation of fasting crowd with significant increase.
Description
Technical field
The present invention relates to medicine preparation and heat limitation field, more particularly, in a kind of mitigation fasting or diet side reaction
Medicine and preparation method thereof.
Background technology
Medically described fasting refers to be daily zero by the heat of alimentary canal dietary intake.But as a kind of health care
Method, the definition of fasting is more wide in range, and the definition with very low calorie diet, which has, to intersect, and refers to the heat taken in daily from alimentary canal
Less than 200-400 kilocalories, so following fasting includes very low calorie diet.
Fasting has been carried out more than 100 years in Europe as a kind of health care therapeutic method, can treat fatty liver, high blood
Press disease, blood fat disorder, obesity and overweight, diabetes B, sleep apnea syndrome, metabolic syndrome；Rheumatism joint
Inflammation, psoriasis, allergy, allergic rhinitis；Constipation, enterogastric diseases, irritable bowel syndrome；Osteoarthritis, tendon disease, back
Bitterly；Asthma, flu, influenza, bronchitis；Candidiasis, headache, menopausal syndrome, smoking, excessive drinking, acne；Etc..
Appropriate fasting can find evidence, mechanism bag in the above-mentioned disease of clinical treatment from many laboratory researches
Autophagy is included, inhibits inflammatory factor, anti-oxidant, stem cell regenerating, be immunized and restart, inhibit tumor growth factor, improve cognitive function,
Etc..
Fasting is not Europe original creation, just has " warding off paddy " health preserving method in the epoch China in even more time immemorial, from road
" not eating five cereals " in family's health, is a kind of common Curing Method of ancients.It starts from the pre-Qin days, is popular in the Tang Dynasty, also known as but paddy,
Go paddy, exhausted paddy, go without food, but grain, stop grain etc..
The earliest record of paddy is warded off to be derived from《The carefree trip of village》：" here the mountain that small aunt penetrates has extraordinary person residence.If skin ice and snow, mire
If about virgin does not eat five cereals, inhale wind and drink dew, multiply thin clouds, drive flying dragon, and swim outside the four seas ... " as a kind of macrobiosis benefit
It is also on the books in many ancient book ancient books and records to ward off paddy for the health rule in longevity.For example,《Wash you》Have " deficiency of food and it is convinced, be that must enjoy day
Year " is said；《Dadailiji easily this life》It says：" food meat person is brave and brave, eats paddy person wisdom and skilful, eats gas person gods and the longevity, no
Trencherman is not dead and refreshing." illustrate that warding off paddy plays the role of promoting longevity.
After Taoism is founded, this art is followed, paddy person is warded off in cultivation, for not incapable persons.Record sweet wormwood application method《Preemergency after elbow
Side》, mono- Taoist priests of author Ge Hongnai,《Baopuzi neipian is miscellaneous should》Middle theory：" remainder is shown in that 2 years 3 years persons of disconnected paddy people are more, all
The light color of body is good.”
Ancients have also spoken of the side reaction for warding off paddy and its solution party in addition to finding to ward off the health cultivation and rehabilitation positive effect of paddy
Case.Western Han Dynastry's book copied on silk that Changsha Mawangdui is unearthed《(but) paddy is gone to eat a gas piece》Cloud：" (but) paddy person is gone to eat pyrrosia lingua.Head weights, foot are light, body
It is cooked a meal and (blown) to sorrowful , Ze Xu (Xu), stops depending on profit." mean the hunger phenomenon that top-heavy limbs fatigue is often generated when warding off paddy,
Solution has two aspects, when the pyrrosia lingua that takes traditional Chinese medicine, first, with " blowing Xu " food gas (convinced), i.e., soft slow elongated breath is received.
The convinced principle for warding off paddy is explained：Saliva, empty gas and water are by swallowing, correct Breathing Method, into alimentary canal
It is interior, nutriment is synthesized in vivo, is sustained life so as to not eat five cereals for a long time.This method may look like psychology
Hint mitigate hunger, it is but incompatible with modern scientific theory.
On using Chinese medicine,《Cloud book box seven is signed》Volume five carries, and Sun You high mountains " eat art but grain, take paddy celestial being ball 67 years, face is color light
Profit, essence are refreshing elegant clean." ward off the medicine that paddy takes, have glutinous rehmannia, sealwort, the fleece-flower root, the fruit of Chinese wolfberry, lucid asparagus, the tuber of dwarf lilyturf, chrysanthemum, Poria cocos,
Rhizoma Atractylodis Macrocephalae, pine nut, cedar seed, the seed of jog's tears, Chinese yam, almond, Radix Paeoniae Alba, calamus, rhizoma alismatis, pyrrosia lingua etc..The Chinese medicine preparation five of each utilization spends eight
Door, but be to carry out the thinking of principle-method-recipe-medicines by the tcm symptom sign occurred to patient during fasting and distinguish without one
Card treats, and effect leaves a question open.
At present in addition to applicant and Chen Dingsheng (the cooperation post-doctor of applicant), almost without for fasting side reaction
Chinese prescription invention.And my previous invention is made of Chinese medicine, can only declare Chinese medicine preparation is made exists by new drug
Hospital circulates, it is impossible to is widely used as food.
According to the research of Chinese fasting treatment founder Qin Jian et al., fasting or diet can ward off paddy and gone out with being similar to
Existing side reaction：Limb is cold, chilly, tired, weak, dizzy bored, thick greasy fur.The core of these side reactions is hunger, can be compeled
The people that fasting in need carries out health care is made to be difficult to adhere to or give up halfway.
We by occur during fasting tcm symptom analysis and Dialectical thought, fasting crowd occur limb it is cold, fear
It is cold, belong to YANG QI deficiency；It is tired, weak, belong to the deficiency of vital energy；It is general that giddy is bored, thick greasy fur belongs to phlegm wet Inner.Fasting process is carried out
Pathogenic analysis, after heat limitation, body is the warm body of yang-energy by cream fat (adipose tissue) change accumulated usually is enabled, but
Substantial amounts of lipid material can be generated during conversion.In theory of traditional Chinese medical science, lipid material is cream fat under physiological status, in disease
It is that phlegm is turbid under reason state.Phlegm is turbid not to be changed, and first cannot switch to the gentle warm body of sun, be second jammed mechanism of qi blood vessels.Thus may be used
See, the turbid Inner of phlegm is general not to be changed, and is that the interpretation of the cause, onset and process of an illness of fasting process is crucial..
The content of the invention
In order to mitigate the hunger of people under fasting state, the relevant side reaction of fasting is eliminated, the present invention provides one kind
Mitigate Chinese medicine of fasting or side reaction of dieting and preparation method thereof.The said preparation principles of formulating prescriptions and the pervious patent phase of the applicant
Seemingly, but medicament selection is entirely different, all by the Chinese medicine system of food and medicament dual-purpose, the prescription of doctor is not required, can exist as food
Market circulate, safety and can extensive use, curative for effect, no toxicity.
Department of Pharmacy applicant of the present invention carries out Syndrome Differentiation of Chinese Medicine according to the symptom occurred during fasting (or stringent diet control)
Card is understood, and then passes through the new Chinese medicine compound preparation of traditional Chinese medical science principle-method-recipe-medicines flow development.By the ginseng, fruit of Chinese wolfberry, arillus longan, white
Ten a herb such as hyacinth bean, jujube, Chinese cassia tree, fructus amomi, dried orange peel, Pogostemon cablin, sealwort, Radix Glycyrrhizae is prepared.Full side link closely fasting or
The interpretation of the cause, onset and process of an illness variation that diet occurs, all medicine compatibilities are reasonable, gather warming YANG and invigorating QI, the work(of clearing damp resolving sputum altogether.Available for fasting prevention it is overweight/
The pair occurred during the metabolic diseases such as fat and associated diabetes, hypertension, hyperlipidemia, fatty liver is anti-
It should.
Drug of the present invention is that acceptable excipient is prepared on bulk pharmaceutical chemicals and pharmacy by following weight parts：
Ginseng 1-3 fructus amomi 1-6 fruit of Chinese wolfberry 10-100 arillus longans 10-100
Semen Lablab Album 10-100 jujube 10-200 Chinese cassia tree 5-50 dried orange peels 5-50
Pogostemon cablin 10-200 sealwort 10-100 Radix Glycyrrhizaes 10-60
The turbid Inner of phlegm is general not to be changed, and is that the interpretation of the cause, onset and process of an illness of fasting process is crucial, so it is emphasis that warm resolving sputum is turbid.Full side is made a general survey of, ten simply
The pharmacological property that Chinese medicine has eight tastes belongs to warm nature, agrees with the interpretation of the cause, onset and process of an illness in the old maxim and feeding process of " sick phlegm and retained fluid person, when with warm medicine and it "
It is crucial.
Wrinkled giant hyssop acrid flavour, tepor can be with dampness elimination, relieving summer-heat, preventing or arresting vomiting；Fructus amomi acrid flavour, it is warm-natured, it can be with dampness elimination promoting the circulation of qi, middle benefit gas；Dried orange peel
Acrid flavour, hardship, it is warm-natured, it can be eliminating dampness and eliminating phlegm；More than three herbal medicines the effect of direct at that phlegm is turbid not to be changed sick and crucial, be altogether monarch drug in a prescription.
Chinese cassia tree acrid flavour, sweet, property heat, mends fire supporing yang, eliminating cold to stop pain, warming meridian in side；Arillus longan is sweet in flavor, warm-natured, can with tonifying heart and spleen,
Nourishing blood and tranquilization；Jujube is sweet in flavor, warm-natured, can be with tonifying middle-Jiao and Qi, nourishing blood and tranquilization, mitigation pharmacological property.This three taste, warming YANG and invigorating QI assist phlegm
Turbid temperature, ministerial drug.Ginseng is sweet in flavor, slight bitter, mild-natured, return lung, spleen, the heart channel of Hang-Shaoyin, can reinforce vital energy, reinforce the spleen to benefit the lung, promoting the production of body fluid, benefit of calming the nerves
Intelligence；Semen Lablab Album is sweet in flavor, slightly warm in nature, can be with tonifying spleen and middle dampness elimination；Sealwort is sweet in flavor, mild-natured, can be with boosting qi and nourishing yin, invigorating the spleen, moistening lung, benefit
Kidney；The fruit of Chinese wolfberry is sweet in flavor, mild-natured, can nourishing liver and kidney, benefiting shrewd head.This four taste mends profit parallel, is for adjutant.Radix Glycyrrhizae is sweet in flavor, property
It is flat, it can invigorate the spleen and benefit qi, relieving spasm to stop pain, can be to make medicine with coordinating the drug actions of a prescription.
Chinese cassia tree, arillus longan, jujube can yang-tonic tongmai, wet dampness elimination, in addition to aversion to cold and cold limbs symptom is released, can also help phlegm turbidity
Solution.Ginseng, Semen Lablab Album, Radix Glycyrrhizae tonifying Qi improve lassitude and weak.The warm and humid resolving sputum of fructus amomi, dried orange peel, wrinkled giant hyssop is dispelled turbid, and is phlegm with qi-regulating
Turbidity solution is opened a way.Sealwort, the fruit of Chinese wolfberry can seek sun by tonifying yin, can not only make full side warm but not dry, but also can make the fountainhead of yang-energy
It is inexhaustible.In addition, person sweet in flavor is more in side, Gan Zhehuan can alleviate the various side reactions occurred during fasting, make fasting process
It is steady smooth.
The weight of above-mentioned raw materials medicine is preferred：
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 100 arillus longan 100
100 jujube of Semen Lablab Album, 200 Chinese cassia tree, 50 dried orange peel 50
200 sealwort of Pogostemon cablin, 100 Radix Glycyrrhizae 60
The weight of above-mentioned raw materials medicine is further preferably：
1 fructus amomi of ginseng, 1 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 15 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
The weight of above-mentioned raw materials medicine is further preferably：
1 fructus amomi of ginseng, 1 fruit of Chinese wolfberry, 60 arillus longan 60
60 jujube of Semen Lablab Album, 150 Chinese cassia tree, 30 dried orange peel 60
200 sealwort of Pogostemon cablin, 60 Radix Glycyrrhizae 30
The weight of above-mentioned raw materials medicine is further preferably：
2 fructus amomi of ginseng, 3 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
The weight of above-mentioned raw materials medicine is further preferably：
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
Drug of the present invention can be prepared into acceptable oral formulations in any pharmacy according to the common process of this field
Dosage form.Wherein preferred powder, oral liquid, tablet, the water-bindered pill, honeyed bolus, capsule.
The powder of the present invention can be prepared as follows method and be made：
By the bulk pharmaceutical chemicals separate or merge add water to cook twice, for the first time plus 5-10 times of water measure, boil 1.5-3 it is small when,
Collect volatile oil；Second plus 4-8 times of water measure, boil 0.5-1.5 it is small when, collect volatile oil.Collecting decoction, filtering, by filtrate
Proportion is concentrated into 60 DEG C as 1.10-1.35, concentrate is released, is diluted with water, when standing 24 is small, supernatant is taken to cross 300-400
Day strainer, concentration, is mixed into the volatile oil of collection, adds appropriate excipient, be spray dried to particle；Pouch is distributed into get powder.
Other preferred dosage forms of the present invention can also be prepared as follows method and be made：
By the bulk pharmaceutical chemicals separate or merge add water to cook twice, for the first time plus 5-10 times of water measure, boil 1.5-3 it is small when,
Collect volatile oil；Second plus 4-8 times of water measure, boil 0.5-1.5 it is small when, collect volatile oil.Collecting decoction, filtering, by filtrate
Proportion is concentrated into 60 DEG C as 1.10-1.35, concentrate is released, is diluted with water, when standing 24 is small, supernatant is taken to cross 300-400
Day strainer, concentration, is mixed into the volatile oil of collection, then routinely oral liquid, tablet, the water answered ability day is respectively prepared in preparation process
Ball, honeyed bolus or capsule.
Beneficial effects of the present invention：The medication combined fasting of the present invention has metabolic syndrome good therapeutic effect, and
Without obvious adverse reaction；The ability of the resistance to starvation of patient can be greatly improved and receive the compliance of diet control.
Description of the drawings
Fig. 1 is that the severity felt corresponds to corresponding score axis.
Specific embodiment
The clinical observation of drug therapy weekend fasting in two days of the present invention
Clinically 33 weekend fasting patients of observed drug of the present invention, are overweight/obesity person.33 patients adhere to
Hunger after this preparation, aversion to cold and cold limbs, lassitude and weak, dizzy self sense such as bored are taken in the weekend fasting of surrounding during fasting
Feel that symptom is commented to be decreased obviously, weight is also decreased obviously, the results showed that the side reaction adjoint to fasting of this drug has apparent slow
Solution acts on, and patient is enable to adhere to 0 heat or extremely low heat two days or more, and can lose weight, and hypoglycemia is had no during use
Reaction and other adverse reactions.
(1) overweight and (or) fat diagnostic criteria：BMI≥25kg/m2；
(2) case inclusion criteria
1. meet the diagnostic criteria of overweight/obesity.
2. between age 18-70 Sui.
(3) case exclusion criteria
1. the age is in under-18s or the patient of 70 years old or more；
2. have in nearly 1 month Diabetic Acute complications (including diabetic Hypoglycemia, diabetic hyperosmolar coma,
Diabetic ketosis and ketoacidosis, diabetic lactoacidosis, Diabetic Acute infection)；
3. merge severe cardiac, the infull patient of Liver and kidney function；
4. mental disease fails partner；
5. gestation or nursing period and preparation gravid woman；
6. loner (refer to cannot coordinate fasting or Chinese medicine cannot be taken by regulation and the person of affecting the treatment；
7. malignant tumour and inpatient with haematological diseases；
8. active tuberculosis patient；
9. the ulcers of serious helmet bleeding；
10.1 diabetes mellitus types；
The control of 11.2 patients with type Ⅰ DM is bad, it is necessary to insulin injection patient；
12. the control of essential hypertension enalapril meleate is not waitd upon, secondary hypertension patient；
13. researcher is deemed unsuitable for enrolled other situations.
(4) all patients of therapy sign informed consent form before treatment is started, if there is high blood pressure, sugar are resistance to
Exception/New-Onset Diabetes Mellitus, dyslipidemia are measured on the basis of former treatment is maintained, weekend fasting is carried out and adds this Chinese medicine, the course for the treatment of
Four weekends.
(5) observation index
1. curative effect index：Hunger before and after this preparation, aversion to cold and cold limbs, lassitude and weak, dizzy bored etc. is taken during fasting
Feel symptom score, before fasting and surrounding fasting at the end of changes of weight.
2. safety indexes：Hypoglycemic incidence, curative compliance, hepatic and renal function, blood routine.
(6) Comprehensive Clinical the standard of curative effect evaluation
Feel the scoring that ten grades are carried out according to 0-9 point, it is hunger, aversion to cold and cold limbs, lassitude and weak, dizzy bored etc.
No
The suitable severity correspondence felt is scored accordingly, as shown in Figure 1,0 point is no any discomfort sense, 9 points
For not tolerable sense of discomfort, feed food is carried out to alleviate.
Curative effect judges
It is 1. effective：Symptom is felt during fasting and declines 3 points or more, after fasting in 4 weeks than expected severity
3.5 kilograms of weight loss or more.
2. effectively：Relatively expected 1 point or more of the decline of symptom is felt during fasting, weight loss 2 is public after fasting in 4 weeks
Jin or more.
It is 3. invalid：More than standard person is not achieved.
It is it is recommended that as follows：
(7) result
1. feel symptom variation (one)
Hunger lassitude and weak
Before taking medicine before number of cases medication after medication after medication
33 7.31±1.23 3.04±0.82 6.57±1.21 2.14±0.52
Patient is present with apparent hunger and lassitude and weak symptom during fasting, and scoring is higher before taking medicine, and takes this
It is decreased obviously after preparation, reaches significant levels.
2. feel symptom variation (two)
Aversion to cold and cold limbs giddy is bored
Before taking medicine before number of cases medication after medication after medication
33 4.28±0.53 1.33±0.23 7.33±1.22 2.14±0.55
Patient is present with apparent aversion to cold and cold limbs and dizzy bored symptom during fasting, and scoring is higher before taking medicine, and takes
It is decreased obviously after this preparation.
3. changes of weight (kilogram)
Before number of cases treatment after treatment
33 82.3±7.9 78.4±6.5
For patient before and after fasting, changes of weight is apparent.
5. Evaluation of Synthetic Effect of Holistic
Clinically drug of the present invention is used for weekend fasting, observes 33 overweight/obesity patients, wherein effective 28, have
Effect 5, invalid 0.
6. safety evaluatio
B ultrasound, which prompts 21, in 33 overweight/obesity patients different degrees of fatty liver, wherein 12 are being treated for the first time
Transaminase index rises during treatment, and more than normal range (NR), but without clinical meaning, transaminase is down to originally after recovering diet
It is below horizontal.Renal function index and blood routine examination no abnormality seen.
33 patients are without apparent hunger, equal finished chemoradiotherapy, and compliance is good.
(8) conclusion
The medication combined fasting of the present invention has good therapeutic effect to metabolic syndrome, and without obvious adverse reaction；It can
With the compliance for the ability of the resistance to starvation of patient being greatly improved He receiving diet control.
Embodiment 1
0.1 fructus amomi of ginseng, 0.1 fruit of Chinese wolfberry, 6 arillus longan 6
6 jujube of Semen Lablab Album, 15 Chinese cassia tree, 3 dried orange peel 3
9 sealwort of Pogostemon cablin, 6 Radix Glycyrrhizae 6
Routinely powder of the present invention is made in formulation method.
Embodiment 2
1 fructus amomi of ginseng, 1 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 15 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
Oral liquid of the present invention is made according to a conventional method.
Embodiment 3
1 fructus amomi of ginseng, 1 fruit of Chinese wolfberry, 60 arillus longan 60
60 jujube of Semen Lablab Album, 150 Chinese cassia tree, 30 dried orange peel 60
200 sealwort of Pogostemon cablin, 60 Radix Glycyrrhizae 60
Tablets are made according to a conventional method.
Embodiment 4
2 fructus amomi of ginseng, 3 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
The water-bindered pill of the present invention is made according to a conventional method.
Embodiment 5
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10
Honeyed bolus of the present invention is made according to a conventional method.
Embodiment 6
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 100 arillus longan 100
100 jujube of Semen Lablab Album, 200 Chinese cassia tree, 50 dried orange peel 50
200 sealwort of Pogostemon cablin, 100 Radix Glycyrrhizae 100
Capsule of the present invention is made according to a conventional method.
Claims (6)
1. it is a kind of mitigate fasting or diet side reaction Chinese medicine, it is characterised in that it be by following weight parts proportioning bulk pharmaceutical chemicals with
Acceptable excipient is prepared in pharmacy：
Ginseng 1-3 fructus amomi 1-6 fruit of Chinese wolfberry 10-100 arillus longans 10-100
Semen Lablab Album 10-100 jujube 10-200 Chinese cassia tree 5-50 dried orange peels 5-50
Pogostemon cablin 10-200 sealwort 10-100 Radix Glycyrrhizaes 10-60.
2. Chinese medicine according to claim 1, it is characterised in that the parts by weight of bulk pharmaceutical chemicals are：
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 100 arillus longan 100
100 jujube of Semen Lablab Album, 200 Chinese cassia tree, 50 dried orange peel 50
200 sealwort of Pogostemon cablin, 100 Radix Glycyrrhizae 60.
3. Chinese medicine according to claim 1, it is characterised in that the parts by weight of bulk pharmaceutical chemicals are：
1 fructus amomi of ginseng, 1 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 15 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10.
4. Chinese medicine according to claim 1, it is characterised in that the parts by weight of bulk pharmaceutical chemicals are：
2 fructus amomi of ginseng, 3 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10.
5. Chinese medicine according to claim 1, it is characterised in that the parts by weight of bulk pharmaceutical chemicals are：
3 fructus amomi of ginseng, 6 fruit of Chinese wolfberry, 10 arillus longan 10
10 jujube of Semen Lablab Album, 10 Chinese cassia tree, 5 dried orange peel 5
10 sealwort of Pogostemon cablin, 10 Radix Glycyrrhizae 10.
6. according to claim 1-5 any one of them Chinese medicines, it is characterised in that：The Chinese medicine is powder, oral liquid, tablet, water
Ball, honeyed bolus or capsule.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611115616.9A CN106729304B (en) | 2016-12-07 | 2016-12-07 | A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201611115616.9A CN106729304B (en) | 2016-12-07 | 2016-12-07 | A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106729304A CN106729304A (en) | 2017-05-31 |
| CN106729304B true CN106729304B (en) | 2018-05-22 |
Family
ID=58877015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201611115616.9A Active CN106729304B (en) | 2016-12-07 | 2016-12-07 | A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106729304B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111184814A (en) * | 2020-03-25 | 2020-05-22 | 明昌平 | A Chinese medicinal composition for treating obesity and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073408A (en) * | 2007-06-15 | 2007-11-21 | 刘志钊 | Nourishing Yuan and removing Gu pills |
-
2016
- 2016-12-07 CN CN201611115616.9A patent/CN106729304B/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101073408A (en) * | 2007-06-15 | 2007-11-21 | 刘志钊 | Nourishing Yuan and removing Gu pills |
Non-Patent Citations (1)
| Title |
|---|
| "《千金翼方》辟谷养生方药探析";梁润英;《中医文献杂志》;20080825;第17页左栏第3段 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106729304A (en) | 2017-05-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100435831C (en) | Preparation for treating high blood pressure, high blood fat, obesity, and climacteric syndrome, and preparation method | |
| CN102293273A (en) | Health tea capable of adjusting blood pressure, blood sugar and blood fat and preventing thrombus and apoplexy | |
| CN102028900A (en) | Traditional Chinese medicine for treating metabolic syndrome and preparation method thereof | |
| CN108524814A (en) | A kind of Chinese medicine composition and preparation method thereof for reducing blood glucose | |
| CN100493572C (en) | Composition of medication for treating diabetes | |
| CN109847027A (en) | A kind of traditional Chinese medicine composition for consolidating root, resolving phlegm and lowering lipid and preparation technology of preparation thereof | |
| CN101032599B (en) | Healthy solution for conditioning skin and losing weight | |
| CN102813870B (en) | Chinese herbal compound preparation used for treating alcoholism and gout and preparation method and application thereof | |
| CN102309705B (en) | Medicine for reducing serum uric acid, preparation method thereof and purpose thereof | |
| CN104491342A (en) | Medicament for treating diabetes and preparation method thereof | |
| CN104208425B (en) | A kind of Chinese medicine preparation for being used to nurse one's health critical hypertension | |
| CN105395706A (en) | Health care product for diabetes | |
| CN102512591B (en) | Composition with functions of losing weight and reducing blood glucose and lipid | |
| CN108403818A (en) | A kind of composition of auxiliary hyperglycemic and application thereof | |
| CN106729304B (en) | A kind of Chinese medicine for mitigating fasting or side reaction of dieting and preparation method thereof | |
| CN107927781B (en) | Traditional Chinese medicine weight-losing meal replacement | |
| CN109528968A (en) | A kind of Chinese medicine composition and its preparation method and application for treating diabetes B | |
| CN101352552B (en) | Capsules for promoting children's intelligence, growth and development | |
| CN108938920A (en) | A kind of Huang ground building wine and preparation method thereof | |
| CN104189038B (en) | Chinese medicine preparation for nursing one's health female pathology health and immunologic function | |
| CN103393938B (en) | Traditional Chinese medicine composition for reducing blood sugar | |
| CN102552677B (en) | Coptis chinensis and radix rehmanniae Anxiao capsule and preparation method thereof | |
| CN102988747B (en) | Aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and preparation method thereof | |
| CN101884760B (en) | Chinese medicinal composition for treating diabetes mellitus and preparation method thereof | |
| CN104758578A (en) | Traditional Chinese medicine composition for treating palpitation |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Qin Lang Inventor after: Qin Jian Inventor before: Qin Lang |
|
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180403 Address after: Room 1005, room 699, Dongfeng East Road, Guangzhou, Guangdong Province Applicant after: Qin Lang Applicant after: Qin Jian Address before: Room 1005, room 699, Dongfeng East Road, Guangzhou, Guangdong Province Applicant before: Qin Lang |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant |