CN102988747B

CN102988747B - Aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and preparation method thereof

Info

Publication number: CN102988747B
Application number: CN201210145975.4A
Authority: CN
Inventors: 陈运章
Original assignee: Individual
Current assignee: Individual
Priority date: 2012-05-14
Filing date: 2012-05-14
Publication date: 2014-11-26
Anticipated expiration: 2032-05-14
Also published as: CN102988747A

Abstract

The invention discloses an aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia and a preparation method of the aristida triseta electuary. The aristida triseta electuary for reducing hypertension, hyperglycemia and hyperlipidemia is prepared from Digou roxburgh rose, chaenomeles speciosa, multiflora rose root, radix cudramiae, radix pseudostellariae, rubia tinctorum madder root and sargentgloryvine stem according a certain weight proportion. The aristida triseta electuary, disclosed by the invention, functions on improving digestion, activating blood and dissolving stasis, eliminating phlegm and removing dampness, regulating blood sugar level, reducing blood fat and reducing cholesterol, takes effect quickly and has good treatment effects as well as high cure rate when being used for treating hypertension, hyperglycemia and hyperlipidemia.

Description

Electuary of three-hypers and preparation method thereof falls in a kind of three thorns

Technical field

The present invention relates to a kind for the treatment of and take medicine and the preparation method that obesity is the metabolism syndrome of basic hypertension, hyperglycemia, hyperlipidemia three-hypers, belong to the field of Chinese medicines.

Background technology

The obesity of take in recent years rises year by year as metabolic syndromes such as basic hyperlipidemia, hypertension, hyperglycemia, and long term can concurrent cardiovascular and cerebrovascular disease, the serious threat mankind's health and lives.Through a large amount of research and clinical confirmation, mankind aging except heredity, is mainly caused by the peroxide injury of self with the various diseases such as fat three-hypers metabolism syndrome that comprise cancer.Human body toxic molecule-free radical (rubbish in body) that moment produces in biochemical process is to remove external by antioxidant system endogenous enzymes in body.In normal human there is 2-3% in oxygen-derived free radicals, and surpassing is exactly anoxia, makes biomembrane in body be subject to radical damage, and lipid peroxide (CPO) raises.Human body is dynamic equilibrium, i.e. balance between oxidative and anti-oxidative.If the activity decreased of the superoxide dismutase of antioxidant system (SOD), glutathion peroxidase (GSH-Px), catalase (CAT) or quantity reduce, will disequilibrium, oxygen-derived free radicals will increase accumulation, causes various diseases to occur and accelerates old and feeble.Obesity is the rising due to cylinder super-oxidation lipid, makes fat metabolic disturbance, and triglyceride accumulation increases the sign causing.Meanwhile low-density lipoprotein cholesterol raises, and HDL-C reduces, and blood fat is raise.Because lipid peroxide generates, increase, free radical increases, and has destroyed cellularity, makes endocrine function generation obstacle, causes carbohydrate metabolism disturbance, blood sugar increasing.The rising formation blood plasma of blood fat, blood glucose is sticky, thick, dense, and vascular endothelial cell is destructurized, and the cholesterol intravasation endothelial injury place raising is attached, and makes vessel wall thickening, and lumen of vessels narrows down and makes hypertension.On this basis, blood fat, cholesterol continuation rising arteriosclerosis have formed.Because the accumulation of cholesterol has formed calculus, the increasing of calculus make blood flow by slowly to being obstructed, cerebrovascular is obstructed, formation cerebral thrombosis, cardiovascular is obstructed, and occurs coronary heart disease.If calculus sheet increases obstruction, cardiovascular and cerebrovascular vessel can form cerebral infarction or heart infarction.It is optional that the disease of current treatment three-hypers there is no desirable medicine, and doctor trained in Western medicine medication can only be also symptomatic treatment, takes medicine all the life, can not effect a radical cure.

Summary of the invention

Therefore there is great demand to the Chinese medicine of effective treatment three-hypers in people, also do not find at present about relevant report of the present invention, the inventor is through a large amount of development tests and by the checking repeatedly of clinical trial, finally work out the Chinese medicine composition of better treatment three-hypers, thereby completed the present invention.

Object of the present invention is just to provide a kind for the treatment of and take the Chinese medicine composition of obesity as basic three-hypers metabolism syndrome.

Another object of the present invention has just been to provide the preparation method of this composition of medicine.

Medicine of the present invention is to select enlightening ditch Fructus Rosae Normalis, Fructus Chaenomelis, Seem Lablab Album, Radix rosae multiflorae, Radix Cudraniae, Folium Rosae Normalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Fructus Tonnae Sinensis, Radix Rubiae, Fructus Carthami tinctorii, Semen Ziziphi Spinosae, Cortex Lycii, Herba Taxilli, Radix Puerariae, Tremella, Ramulus Mori, Radix Angelicae Pubescentis, Rhizoma Alismatis, Herba Polygoni Avicularis, Rhizoma Polygonati Odorati, Fructus Lycii, Caulis Sargentodoxae combines, make each medicine produce mutually synergism these drug regimens, thereby can treat three-hypers disease palindromia, wherein select principal agent enlightening ditch Fructus Rosae Normalis to be because the wild original single-lobe Fructus Rosae Normalis that enlightening ditch Fructus Rosae Normalis is the inventor to be used special technology to go through to take pains to foster for more than 20 year, this kind only China is exclusive, wild resource is few.Within 1987, from Sichuan Jiangjin County, after identifying, the deputy director Lai Peihan engineer of Simian Mountain orest management institute introduces.Fructus Rosae Normalis is containing 16 kinds of hydrogen base acid, superoxide dismutase (SOD), every hectogram fresh fruit is containing 2400 milligrams of VC, claim VC, VP " king ", also contain abundant VE, VD, VK, carotene, thiamine (b1), riboflavin (b2), folic acid (b14), also containing valley head alcohol, stearic acid, linolenic acid, roxburic acid, protein, triterpenoid saponin, flavochrome, tannin, essence, calcium, magnesium, phosphorus, ferrum, zinc.Carry out five indices check through biology department of Qinhua Univ., Beijing and St Foods Q Supervision & Testing Center to dried roxburgh rose fruit in November, 1997, < < St Foods Q Supervision & Testing Center > > survey report, result confirms, the medicinal component of enlightening ditch Fructus Rosae Normalis has increased precious trace element-selenium newly, Radix Dauci Sativae content increases 2-3 doubly, the scientific research personnel that inventor You Dao Beijing Medical University finds associate professor Song Yuanju to lead, takes the anticancer laboratory data of Fructus Rosae Normalis in 1986 therefrom.Select Fructus Chaenomelis, claim again Fructus Chaenomelis to be because Fructus Chaenomelis is the Fructus Chaenomelis that Xuancheng Profile, anhui Province produces, practise and claim Fructus Chaenomelis, its nature and flavor acid, temperature, enters liver, spleen channel, has suppressing the hyperactive liver and easing the stomach, and the function of the relaxing muscles and tendons that dries is controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen edema.Select Seem Lablab Album to be because its nature and flavor are sweet, flat, enter spleen, stomach warp, have spleen invigorating and in, the function of the removing dampness of relieving summer heat, controls heat-damp in summer and vomits and diarrhoea, insufficiency of the spleen vomiting, lack of appetite chronic diarrhea, water retention is quenched one's thirst, leucorrhea with red and white discharge, infantile malnutrition.Selecting Radix rosae multiflorae, have another name called thorn Mi root, is because its nature and flavor are pained, cool, enters spleen, stomach warp, has clearing away heat-damp and promoting diuresis, dispels the wind, invigorate blood circulation, the function of removing toxic substances, controls lung abscess, quench one's thirst, and dysentery, arthritis, paralysis, tell, be defeated in battle, have blood in stool, frequent micturition, the enuresis, menoxenia, traumatic injury, furuncle scabies.Selecting Radix Cudraniae, have another name called three-bristle cudrania thorn root, is because its property mildly bitter flavor is cool, has expelling wind and removing dampness, and the function of promoting blood circulation to restore menstrual flow, can treat traumatic injury, jaundice, stranguria with turbid discharge, impairment caused by overstrain hemoptysis, dispelling the wind and dampness pathogens arthralgia, skin infection scabies.Select Folium Rosae Normalis to be because it has treatment scabies, carbuncle, the function of incised wound.In addition, the inventor is alone enlightening ditch Folium Rosae Normalis treatment diabetics repeatedly once, reducing blood sugar and blood fat successful.Select Fructus Citri Sarcodactylis, different name Fructus Citri Sarcodactylis, Bergamot, be because the arduous acid of its nature and flavor, and temperature, enters liver, stomach warp, regulates the flow of vital energy, and the function of reducing phlegm, treats for stomachache, coerce swollen, vomiting, dysphagic, phlegm retention cough with asthma, and relieving the effect of alcohol.Selecting Radix Pseudostellariae is that tepor, enters the heart, spleen, lung three warps, has the function of tonifying the lung, spleen invigorating, controls cough due to deficiency of the lung because of its nature and flavor sweetness and bitterness, insufficiency of the spleen lack of appetite, and cardiopalmus order antiperspirant, spirit is tired.Select Fructus Tonnae Sinensis to be because its nature and flavor temperature is arduous, enter liver lung meridian, dispel the wind, cold expelling, the function of pain relieving, controls wind and cold diseases caused by exogenous pathogenic factor, heart peratodynia.Selecting Radix Rubiae is because of its nature and flavor bitter cold, and GUIXIN Liver Channel has promoting the circulation of blood hemostasis, and the function of dredge the meridian passage, controls haematemesis hematuria, metrorrhagia, rheumatic arthralgia, jaundice, chronic tracheitis.Select Fructus Carthami tinctorii, different name SEMEN CARTHAMI, is because it has the function of promoting blood circulation and detoxication, can reduce cholesterol, reduces blood fat, expansion and vessel softening, endocrine regulation.Select Semen Ziziphi Spinosae to be because its nature and flavor are sweet, flat, enter the heart, spleen, liver, gallbladder meridian, there is nourishing the liver, mind calming, calms the nerves, and the function of arresting sweating, controls restlessness of asrhenia type and insomnia, palpitation with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.Select Cortex Lycii to be because its nature and flavor are sweet, cold, enter lung, liver, kidney channel, there is heat clearing away, the function of removing heat from blood, controls asthenia hectic fever night sweat, and lung-heat cough with asthma is spitted blood, epistaxis, stranguria with blood, quenches one's thirst, hypertension, carbuncle, malignant boil.Select Herba Taxilli to be because its property bitter but sweet flavor is flat, enter liver, kidney channel, have invigorating the liver and kidney, bone and muscle strengthening, except rheumatism, the meridian dredging, beneficial blood, antiabortive function, controls soreness of waist and knee joint, a little less than muscles and bones flaccidity, hemiplegia, beriberi, anemofrigid-damp arthralgia, vaginal bleeding during pregnancy metrorrhagia, lack of lactation after delivery.Select Radix Puerariae to be because its nature and flavor are sweet pungent, flat, enter spleen, stomach warp, there is yang invigorating expelling pathogenic factors from muscles, rash antidiarrheal, the function that relieving restlessness is only drunk, cures the wound cold, cures the wound cold, warm headache stiffness of the nape, dysphoria with smothery sensation is quenched one's thirst, has loose bowels, dysentery, skin eruption is not saturating, hypertension, angina pectoris, deafness.Selecting Tremella, have another name called Tremella, is because its nature and flavor are sweet flat, has YIN nourishing, lung moistening, and nourishing the stomach, the function of promoting the production of body fluid, controls cough due to consumptive disease, sputum mixed with blood, deficiency-heat is thirsty.Select Ramulus Mori to be because its nature and flavor are bitter, flat, enter Liver Channel, there is wind-damp dispelling, sharp joint, the function of row aqueous vapor, controls anemofrigid-damp arthralgia, spasm of the limbs, beriberi edema, human body pruritus due to wind pathogen.Select Radix Angelicae Pubescentis to be because its nature and flavor are arduous, temperature, enters kidney, urinary bladder channel, dispels the wind, and victory is wet, cold expelling, and the function of pain relieving, controls anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Select Rhizoma Alismatis to be because its nature and flavor are sweet, cold, enter urinary bladder channel, there is diuretic, eliminating dampness by diuresis, the function expelling the heat-evil, controls dysuria, and edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Choosing is because its nature and flavor are bitter with Herba Polygoni Avicularis, cold, enters urinary bladder channel, has diuresis, heat clearing away, and the function of parasite killing, controls pyretic stranguria, the difficulty in urination, jaundice, the erosion of the vulva, leucorrhea, ascarid, infantile malnutrition, hemorrhoid are swollen, eczema.Select Rhizoma Polygonati Odorati to be because its nature and flavor are sweet, flat, enter lung, stomach warp, has yin nourishing, moisturizes, relieving restlessness, the function of quenching the thirst, controls calentura sun wound, cough, excessive thirst, deficient fever, rapid digestion of food is easily hungry, frequent micturition.Select Fructus Lycii to be because its nature and flavor are sweet, flat, there is nourishing kidney, lung moistening, tonifying liver, the function of improving eyesight, controls hepatic and renal YIN deficiency, and soreness of the waist and knees is had a dizzy spell, the many tear of blurred vision, cough due to consumptive disease, quenches one's thirst, and loses clear.Select Caulis Sargentodoxae to be because its nature and flavor are bitter, flat, enter liver, large intestine two warps, the eliminating carbuncle that relieves internal heat, promoting blood circulation to remove obstruction in the collateral, the function of wind dispelling insecticide, controls acute and chronic appendicitis, rheumatic arthralgia, bloody dysentery, stranguria with blood, menoxenia, infantile malnutrition, worm pain, injury from falling down.

The first-selected enlightening ditch of the present invention Fructus Rosae Normalis, thorn Mi root, three-bristle cudrania thorn root form three thorn electuaries.In the enlightening ditch Fructus Rosae Normalis that wherein inventor cultivates, containing superoxide dismutase (SOD) is macromolecular compound, is one of main endogenous enzymes of human body antioxidant system, is strong anti-oxidation active substance, and free radical scavenging activity is reached to 99%; Trace element-selenium is one of definite needed by human nutrition of the United Nations's health organization, by physician, claimed " anticancer king " to form glutathione peroxidase active center, selenium can strengthen the activity at this center, make its oxidation resistance stronger 500 times than vitamin E, effectively remove free radical, selenium is antioxidation reinforcing agent, can have the ability of obvious promotion cellular uptake sugar, has the identical effect of insulin of pancreatic secretion; Carotene anti-cancer successful, can anti-Common Cold, can cough-relieving, can blood fat reducing, blood sugar lowering, and there is the function of antioxidation, protection cardiovascular and cerebrovascular vessel and neurocyte, a carotene molecule can transform 4 A molecules; Experiment showed, that vitamin A can make the secretory volume of thrombolytic brinase active factors increase by 3.7 times, scientific research also shows, uses vitamin A and the C of equivalent, and the secretory volume of active factors rises to 21 times, is up to 50 times; Vitamin C is antioxidant, can reduce blood cholesterol and capillary fragility, can obviously alleviate diabetic symptom; Vitamin E is the Natural antioxidant, and at the collaborative lower more effective removing free radical of A, C, Citrin can strengthen the adhesion strength between human body cell, can prevent angiorrbagia, and protection blood vessel makes it to keep normal physiological function; Vitamin D can reduce capillary fragility, prevents microvascular bleeding, and has the effect that reduces cholesterol; Rigid acid, linolenic acid scalable lipid metabolism wadding disorderly, maintain the normal physiological function of cell membrane, and treatment and prevention of obesity are sick; Tannin can reduce blood fat.The traditional Chinese medical science thinks that enlightening ditch Fructus Rosae Normalis has invigorating the stomach and promoting digestion, activating QI to eliminate phlegm, blood circulation promoting and blood stasis dispelling, inducing diuresis and reducing edema, strengthening by means of tonics, Xing Yang calms the nerves and the function of two-ways regulation.The catalase that Fructus Chaenomelis in compatibility drug contains (Chinese herbal medicine color atlas, Fujian science tech publishing house, nineteen ninety, Foochow) be one of three kinds of endogenous enzymes of human body antioxidant system, other two kinds is above-mentioned superoxide dismutase and glutathion peroxidase.The collaborative oxidation resistance that strengthens human body antioxygen system of we's Fructus Chaenomelis, has corrected unbalance between human body oxidative and anti-oxidative, makes human body keep the dynamic equilibrium of normal physiological.Seem Lablab Album in side, Radix Pseudostellariae, Rhizoma Polygonati Odorati, Fructus Lycii help with boosting qi and nourishing yin, three-bristle cudrania thorn root, Radix rosae multiflorae, Radix Rubiae, Caulis Sargentodoxae etc. help with cool the blood dissipate blood stasis, promoting blood circulation to restore menstrual flow, Fructus Citri Sarcodactylis, Tonnae Sinensis fruit, Fructus Chaenomelis help with activating QI to eliminate phlegm, stomach function regulating removing dampness, SEMEN CARTHAMI can reduce cholesterol, reduce blood fat, expansion and vessel softening, endocrine regulation, Folium Rosae Normalis, Tremella, the blood fat reducing of Rhizoma Alismatis energy, blood sugar lowering, Cortex Lycii blood sugar lowering, reduction cholesterol.Radix Puerariae blood sugar lowering, blood pressure lowering, Herba Taxilli ， Herba Polygoni Avicularis, Radix Angelicae Pubescentis, the Semen Ziziphi Spinosae etc. in addition of blood pressure lowering.The traditional Chinese medical science thinks that human body be take and leads to as mending, and it is neither raw that human body reaches five-way all kinds of diseases and ailments.We not only mend but also logical, logical stagnant, logical refuse, logical cardiovascular and cerebrovascular vessel, ventilation, logical convenient to both.We's medicine mutually collaborative, interact and each composition between curative effect after effect, reached medicine (effectiveness) gas (cause of disease) and be harmonious, the drum responding perfectly to the drumsticks, human body is had and wet just remove, have expectorant just to change, have what just broken, have empty just benefit, have fertilizer just to subtract, nothing is fertile in anti-normal physiological state.

The selected principal agent enlightening of the present invention ditch Fructus Rosae Normalis, thorn Mi root, three-bristle cudrania thorn root, be equipped with accessory drugs combination and make three thorns and fall three-hypers electuary.

The constituent content of medicine of the present invention is also that inventor draws through a large amount of Test Summaries, and the consumption of each component has good curative effect within the scope of following weight:

15-25 gram of Fructus Chaenomelis 8-12 of enlightening ditch Fructus Rosae Normalis gram Seem Lablab Album 8-12 gram

Radix rosae multiflorae 8-12 gram of Radix Cudraniae 8-12 gram of Folium Rosae Normalis 5-10 gram

Fructus Citri Sarcodactylis 5-10 gram of Radix Pseudostellariae 8-12 gram of Fructus Tonnae Sinensis 5-10 gram

Radix Rubiae 8-12 gram of Fructus Carthami tinctorii 2-5 gram of Semen Ziziphi Spinosae 8-12 gram

Cortex Lycii 8-12 gram of Herba Taxilli 8-12 gram of Radix Puerariae 8-12 gram

Tremella 5-10 gram of Ramulus Mori 8-12 gram of Radix Angelicae Pubescentis 2-5 gram

Rhizoma Alismatis 5-8 Ke pivot holds 8-12 gram of Rhizoma Polygonati Odorati 8-12 gram

Fructus Lycii 5-10 gram of Caulis Sargentodoxae 8-12 gram

Preferable amount is

9 grams, 9 grams of Seem Lablab Albums of 18 grams of Fructus Chaenomelis of enlightening ditch Fructus Rosae Normalis

6 grams of 9 grams of Folium Rosae Normaliss of 9 grams of Radix Cudraniaes of Radix rosae multiflorae

6 grams of 9 grams of Fructus Tonnae Sinensis of 6 grams of Radix Pseudostellariaes of Fructus Citri Sarcodactylis

9 grams of 3 grams of Semen Ziziphi Spinosaes of 6 grams of Fructus Carthami tinctoriis of Radix Rubiae

9 grams of 9 grams of Radix Puerariaes of 9 grams of Herba Taxillis of Cortex Lycii

3 grams of 9 grams of Radix Angelicae Pubescentiss of 6 grams of Ramulus Moris of Tremella

Rhizoma Alismatis 6 Ke pivots hold 9 grams of 9 grams of Rhizoma Polygonati Odorati

9 grams of 6 grams of Caulis Sargentodoxae of Fructus Lycii

Preparation method of the present invention is as follows

One, get the raw materials ready

1, enlightening ditch Fructus Rosae Normalis: choose high-quality Fructus Rosae Normalis fresh fruit, clear water is cleaned, and section, dries;

2, Fructus Chaenomelis: choose high-quality Fructus Chaenomelis fresh fruit, clear water is cleaned, and section, dries;

3, Seem Lablab Album: choose clean impurity, put in boiling water and slightly boil, heave, softly pull out for degree to planting skin, immerse in cold water, slough skin, dry;

4, Radix rosae multiflorae: choose clean impurity, clean and dry;

5, Radix Cudraniae: clean, run through, oblique section, dries;

6, Folium Rosae Normalis: choose clean impurity, dry;

7, Fructus Citri Sarcodactylis: choose decontamination, after water spray profit, chopping, dries;

8, Radix Pseudostellariae: extract fibrous root, dry;

9, Fructus Tonnae Sinensis: gather autumn, dries;

10, Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through rear timely section, dry;

11, Fructus Carthami tinctorii: choose clean impurity, dry;

12, Semen Ziziphi Spinosae: former medicine is put into bamboo square-bottomed bamboo basket, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, and thorn core is pulled out, dries;

13, Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;

14, Herba Taxilli: former medicine washes, runs through, and cutting, dries;

15, Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;

16, Tremella: choose decontamination, dry or dry;

17, Ramulus Mori: choose decontamination, clean, be soaked in water, after running through, cutting, dries;

18, Radix Angelicae Pubescentis: choose decontamination, separately size, cleans, and runs through rear section, dry;

19, Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;

20,, Herba Polygoni Avicularis: remove impurity and root, clean, soften, cutting is dried;

21, Rhizoma Polygonati Odorati: remove impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;

22, Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;

23, Caulis Sargentodoxae: be soaked in water, clean spare, run through, section, dries.

Two, preparation

1, for preventing the loss of the active ingredients such as VC, get the low temperature 50-60 ℃ oven dry fast within the shortest time of the enlightening ditch Fructus Rosae Normalis of above-mentioned weight and the fresh fruit of Fructus Chaenomelis, wear into fine powder with Fructus Carthami tinctorii;

2, the Seem Lablab Album of above-mentioned weight, Radix rosae multiflorae, Radix Cudraniae, Folium Rosae Normalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Fructus Tonnae Sinensis, Radix Rubiae, Semen Ziziphi Spinosae, Cortex Lycii, Herba Taxilli, Radix Puerariae, Tremella, Ramulus Mori, Radix Angelicae Pubescentis, Rhizoma Alismatis, Herba Polygoni Avicularis, Rhizoma Polygonati Odorati, Fructus Lycii, Caulis Sargentodoxae are put into the container of boiling medicine and add 4 times of amounts of water, intense fire decocts boiling, slow fire boiling 20 minutes, crosses leaching decoction liquor for the first time.The medicinal residues of filtration are added to 2 times of amounts of water, and intense fire decocts boiling, and slow fire boiling 20 minutes is filtered, and gets decoction liquor for the second time;

3, merge twice decoction liquor, intense fire decocts after boiling, then uses slow fire boiling 10 minutes, is condensed into extract;

4, extract is sprayed and fully to be mixed thoroughly on enlightening ditch Fructus Rosae Normalis, Fructus Chaenomelis, Fructus Carthami tinctorii fine powder, granule electuary, dry after sterilization packaging, 4.5 grams every bag.

Medicine of the present invention has invigorating the stomach and promoting digestion, blood circulation promoting and blood stasis dispelling, and dampness removing reduces phlegm, and reduces cholesterol, reduces blood glucose, blood fat, and the function of expansion and vessel softening is used for the treatment of and take hypertension, hyperlipidemia, the hyperglycemia instant effect that obesity is feature, good effect, cure rate is high.

The specific embodiment

Below by test example, further set forth beneficial effect of the present invention, these test examples comprise animal experiment and clinical observation material.

The report of [test example 1] animal toxicity test

Get 40 of new zealand rabbits, body weight 2.0-2.5kg, male and female dual-purpose, is divided into two groups, and 20 every group, wherein one group is normal amount test group, and another group is super quantity test group.The medication of normal amount group is 10ml/kg, and excess group is 20ml/kg, and administering mode is administration by gavage administration, and every day, each once, serve on one week sooner or later, observed medication reaction every day.Result shows: two groups of rabbit diet activities are normal, and medicine is without bad toxic and side effects.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data:

Accept outpatient service obesity, three-hypers Metabolic Syndrome Patients 216 examples for medical treatment, 15 example premature coronary heart diseases wherein, 11 examples are with sequal of cerebrovascular diseases, male 102 examples in 216 examples, female's 114 examples, age 40-50 year 42 examples, 51-60 year 98 examples, 61-70 year 62 examples, 70 years old above 14 example.Course of disease 2-15.

2, diagnostic criteria:

Three-hypers metabolic syndrome is mainly in 40 years old above middle-older patient, and the multiple focus of patient takes place frequently.

216 examples are apart from outside the above hospital inspection list in county, clinical symptoms: be obesity, dizziness, headache, nose heave dizzy, weak, breathe hard, uncomfortable in chest, numb limbs and tense tendons, palpitation and insomnia, susceptible to lose temper due to restlessness, chest and hypochondrium etc., sequal of cerebrovascular diseases patient speech disorder, facial paralysis, extremity are unsuccessful etc.

3, therapeutic modality:

Every day secondary, each 1 bag, warm boiled water, two months is a course for the treatment of, serve on 2-3 the course for the treatment of.

4, efficacy assessment standard:

Effective: patient's transference cure, it is normal that body constitution is recovered, and follows up a case by regular visits to half a year without recidivist;

Take a turn for the better: patient body recovers normally substantially, and body constitution progressively takes a turn for the better;

Invalid: not reach improvement standard person.

5, therapeutic effect:

Obesity: 216 routine patients are 151 examples effective (effective standard is that the Body Mass Index arm's length standard of formulating with reference to the Asian-Pacific area is man 25, and female 24) wherein, and obesity symptom disappears, and Body Mass Index is normal, man 25, female 24; 60 examples take a turn for the better, and obesity symptom disappears substantially; 5 examples are invalid, and total effective rate is 97.68%.

Hyperlipemia: 216 routine patients wherein 135 examples are effective, serum cholesterol, triglyceride, three indexs of high density lipoprotein within normal range, sensation of oppression over the chest with shortness of breath, numb limbs and tense tendons, dizzy nose heave, the transference cure such as abundant expectoration mouth is sticky.79 examples take a turn for the better, and three indexs approach normally, and symptom disappears substantially.Clinical symptoms is improved greatly, invalid 2 examples, and total effective rate is 99.07%.

Hypertension: 216 routine patients wherein 113 examples are effective, blood pressure stabilization is within normal range more than 1 year, and headache is dizzy, cardio palmus shape disappears.98 examples take a turn for the better, and blood pressure approaches normal, and clinical symptoms disappears substantially, and 5 examples are invalid, and total effective rate is 97.68%.

Hyperglycemia: 216 routine patients wherein 72 examples are effective, fasting glucose <6.2mmo1/L, 2 hours blood glucose <7.3mmol/L after meal, clinical symptoms aching pain in waist and back, limb fiber crops limb pain, dry mouth and throat, weak, breathe hard, spontaneous sweating, thirst and liking drink, stool unites to disappear.102 examples take a turn for the better, fasting glucose <7.2mmo1/L, and 2 hours blood glucose 8.3 mmo1/L after meal, symptom disappears substantially.36 examples progressively take a turn for the better, fasting glucose <8.3 mmo1/L, and 2 hours blood glucose <10 mmo1/L after meal, partial symptoms disappears, invalid 6 examples, total effective rate is 97.22%.

Coronary heart disease: 216 routine patients wherein 15 examples have 11 examples effective after treatment with coronary disease patient, it is normal that electrocardiogram recovers, and angina pectoris, cardiopalmus, the cardinal symptom uncomfortable in chest of breathing hard disappear, and 2 routine electrocardiograms improve, and cardinal symptom alleviates, invalid 2 examples, total effective rate is 86.66%.

Cerebrovascular: 216 routine patients wherein 11 routine sequal of cerebrovascular diseases persons treat after 7 examples effective, clinical symptom disappearance, recovers orthobiosis, 2 routine cardinal symptoms disappear substantially, quality of life improves greatly, invalid 2 examples, total effective rate is 81.81%.

Claims

1. an instant particles as Chinese medicine that falls three-hypers, is characterized in that: it is to be made by the crude drug within the scope of following weight:

Cortex Lycii 8-12 gram of Herba Taxilli 8-12 gram of Radix Puerariae 8-12 gram

Fructus Lycii 5-10 gram of Caulis Sargentodoxae 8-12 gram.

2. electuary according to claim 1, wherein the consumption of each crude drug is:

9 grams of 6 grams of Caulis Sargentodoxae of Fructus Lycii.

3. according to the preparation method of electuary described in claim 1 or 2, it is characterized in that: it comprises the following steps:

(1) get the raw materials ready

(1) enlightening ditch Fructus Rosae Normalis: choose high-quality Fructus Rosae Normalis fresh fruit, clear water is cleaned, and section, dries;

(2) Fructus Chaenomelis: choose high-quality Fructus Chaenomelis fresh fruit, clear water is cleaned, and section, dries;

(3) Seem Lablab Album: choose clean impurity, put in boiling water and slightly boil, heave, softly pull out for degree to planting skin, immerse in cold water, slough skin, dry;

(4) Radix rosae multiflorae: choose clean impurity, clean and dry;

(5) Radix Cudraniae: clean, run through, oblique section, dries;

(6) Folium Rosae Normalis: choose clean impurity, dry;

(7) Fructus Citri Sarcodactylis: choose decontamination, after water spray profit, chopping, dries;

(8) Radix Pseudostellariae: extract fibrous root, dry;

(9) Fructus Tonnae Sinensis: gather autumn, dries;

(10) Radix Rubiae: choose clean impurity, remove Lu Miao, clean, run through rear timely section, dry;

(11) Fructus Carthami tinctorii: choose clean impurity, dry;

(12) Semen Ziziphi Spinosae: former medicine is put into bamboo square-bottomed bamboo basket, sinks in clear water cylinder, and core is kept afloat, and shell is heavy water-bed, and thorn core is pulled out, dries;

(13) Cortex Lycii: choose decontamination and core, slightly wash, dry, cutting;

(14) Herba Taxilli: former medicine washes, runs through, and cutting, dries;

(15) Radix Puerariae: choose decontamination, clean, be soaked in water, pull out, run through, section, dries in time;

(16) Tremella: choose decontamination, dry or dry;

(17) Ramulus Mori: choose decontamination, clean, be soaked in water, after running through, cutting, dries;

(18) Radix Angelicae Pubescentis: choose decontamination, separately size, cleans, and runs through rear section, dry;

(19) Rhizoma Alismatis: choose decontamination, big or small stepping, is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section, dries;

(20) Herba Polygoni Avicularis: remove impurity and root, clean, soften, cutting is dried;

(21) Rhizoma Polygonati Odorati: remove impurity, clean earth, moistening is even to inside and outside humidity, and section, dries;

(22) Fructus Lycii: the clean impurity of winnowing with a dustpan, pluck residual stalk and the base of a fruit;

(23) Caulis Sargentodoxae: be soaked in water, clean spare, run through, section, dries;

(2) preparation

(1) for preventing the loss of the active ingredients such as VC, get the low temperature 50-60 ℃ oven dry fast within the shortest time of the enlightening ditch Fructus Rosae Normalis of above-mentioned weight and the fresh fruit of Fructus Chaenomelis, wear into fine powder with Fructus Carthami tinctorii;

(2) Seem Lablab Album of above-mentioned weight, Radix rosae multiflorae, Radix Cudraniae, Folium Rosae Normalis, Fructus Citri Sarcodactylis, Radix Pseudostellariae, Fructus Tonnae Sinensis, Radix Rubiae, Semen Ziziphi Spinosae, Cortex Lycii, Herba Taxilli, Radix Puerariae, Tremella, Ramulus Mori, Radix Angelicae Pubescentis, Rhizoma Alismatis, Herba Polygoni Avicularis, Rhizoma Polygonati Odorati, Fructus Lycii, Caulis Sargentodoxae are put into the container of boiling medicine and add 4 times of amounts of water, intense fire decocts boiling, slow fire boiling 20 minutes, cross leaching decoction liquor for the first time, the medicinal residues of filtration are added to 2 times of amounts of water, intense fire decocts boiling, slow fire boiling 20 minutes, filter, get decoction liquor for the second time;

(3) merge twice decoction liquor, intense fire decocts after boiling, then uses slow fire boiling 10 minutes, is condensed into extract;

(4) extract is sprayed and fully to be mixed thoroughly on enlightening ditch Fructus Rosae Normalis, Fructus Chaenomelis, Fructus Carthami tinctorii fine powder, granule electuary, dry after sterilization packaging, 4.5 grams every bag.