CN106727026A - A kind of Chinese medicine acne-removing composition and its application - Google Patents
A kind of Chinese medicine acne-removing composition and its application Download PDFInfo
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- CN106727026A CN106727026A CN201710032667.3A CN201710032667A CN106727026A CN 106727026 A CN106727026 A CN 106727026A CN 201710032667 A CN201710032667 A CN 201710032667A CN 106727026 A CN106727026 A CN 106727026A
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- chinese medicine
- acne
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- skin
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Classifications
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- A—HUMAN NECESSITIES
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Abstract
The invention belongs to cosmetic technical field, it is related to a kind of Chinese medicine acne-removing composition and its application.A kind of various raw material medicines in portions by weight of Chinese medicine acne-removing composition include：0.01 10 parts of Rhizoma Chuanxiong extract, 0.01 20 parts of shrubby sophora extract, 18 parts of the compound of glauber-salt and liquorice.Ligusticum wallichii can improve facial blood circulation, the metabolism renewal of enhancing skin；Kuh-seng anti-inflammation, can effectively kill except acarid, Propionibacterium etc., alleviate pruitus；Compound of glauber-salt and liquorice Qinghuo Jiedu, plays toxin-expelling and face nourishing effect.Three taste Chinese medicine scientific compatibilities, are prepared from through modern science and technology, and Clinical Practice is proved, the Chinese medicine acne-removing composition that the present invention is provided can be used for anti-acne skin preparations for extenal use, and the natural safety of skin is not stimulated, and can effectively dispel each vaccination flesh, recover the ruddy gloss of acne print skin.
Description
Technical field
The invention belongs to daily cosmetics preparing technical field, especially a kind of Chinese medicine composition containing natural anti-acne composition
And its application.
Background technology
Acne is commonly called as whelk, is the sebaceous glands chronic disease for betiding puberty and manhood, mainly normal by skin
It is intracellular to post bacterium Propiobacterium and cause.Propiobacterium is a kind of anaerobic bacteria, when sebum block hair follicle, skin cannot eupnea,
Propiobacterium will be bred with the split speed of nearly ten thousand times per second, so as to aggravate clogging of pores, make diseased region wider, deeper.
Mainly there is the abundant position of sebaceous glands, face, neck, shirtfront back etc. in acne, the performance of small pox is from gently to being again black hoary hair
Head acne, inflamed papules and warts, tumour and tubercle, part population can lose scar, and severe patient can cause to disfeature.
Product for resolving poxes on the market can be divided into the addition of pure Chinese medicine herb extract and be contained change by the source point of active ingredient
Learn synthesis material addition.Source, the species and content of acne-eliminating cosmetic active ingredient not only determine the quality of anti-acne effect, also
The health of consumer is influenceed to a certain extent.At present on the market, some product for resolving poxes are often added to pursue significant effect
The anti-acne active ingredient such as antibiotic, hormone or chemical substance that some have larger stimulation to skin, such as, and chloramphenicol, salt
The pharmaceutical antibiotics such as sour aureomycin, quadracycline, Doxycycline Hyclate, hydrochloric acid minocycline, Oxytetracycline Dihydrate, metronidazole,
Dexamethasone sodium phosphate acceptable glucocorticoid, salicylic acid etc..
The patent disclosure of the A of publication number CN 103536716《A kind of pox-eliminating whitening solution》With publication number CN
The patent of 103070804A《Acne removing skin-cleaning liquid》, the anti-acne active ingredient that it is announced is only salicylic acid；Publication number CN
The patent of 103479661 A《A kind of whitening removing acne and freckle beauty medicine》, its announce anti-acne active ingredient chloramphenicol injection, Ah
Coffee phenol dissipates, lincomycin hydrochloride and lidocaine hydrochloride gel, compound ketoconazole ointment, is antibioticses, the glucocorticoid of chemistry addition
Class anti-acne composition.However, the product long-term use containing hormone easily forms skin dependence facial dermatitis, antibiotic is also easy to produce resistance
Property, salicylic acid has certain excitant, although such product for resolving poxes is used and has certain therapeutic effect, easily least, dependence
Property it is strong, not lasting.《Cosmetics health specification》(version in 2002) specifies antibioticses and glucocorticoids is banned substance, water
Poplar acid is regulated substance.
Therefore, a kind of safer, gentle, effective acne-eliminating cosmetic is developed into active demand.Chinese medicine cosmetic is selected
With Chinese herbal medicine natural herb effective component extracting, natural, environmental protection, security, do not stimulate gently, meet people advocate nature, time
Return traditional trend.
The content of the invention
The present invention is just being directed to above technical problem, there is provided a kind of Chinese medicine acne-removing composition, said composition medical knowledge according in
By, extracted by modern crafts and be prepared from, each taste herbal function of Ligusticum wallichii, kuh-seng, the compound of glauber-salt and liquorice can be given full play to, natural, effect
It is good, non-stimulated.
Another object of the present invention is to provide a kind of application of above-mentioned Chinese medicine acne-removing composition.
Concrete technical scheme of the invention is as follows：
A kind of anti acne of traditional Chinese medicine composition, by the bulk drug of following weight portion：
Rhizoma Chuanxiong extract 0.01-10 parts, shrubby sophora extract 0.01-20 parts, compound of glauber-salt and liquorice 1-8 parts.
Preferably, a kind of Chinese medicine composition, by the bulk drug of following weight portion：
Rhizoma Chuanxiong extract 0.05-5 parts, shrubby sophora extract 0.1-5 parts, compound of glauber-salt and liquorice 2-5 parts.
Still more preferably, a kind of Chinese medicine composition, by the bulk drug of following weight portion：
Rhizoma Chuanxiong extract 0.1-2 parts, shrubby sophora extract 0.1-3 parts, compound of glauber-salt and liquorice 2-4 parts.
In the present invention, the preparation method of anti acne of traditional Chinese medicine composition is comprised the following steps：
A. prepared by Rhizoma Chuanxiong extract：Ligusticum chuanxiong Hort collects filtrate through water extraction, and filtrate takes sediment fraction, deionization through alcohol precipitation
Water dissolves, as component 1.
In above-mentioned steps a, further, it is preferred that including by the filtrate after concentration, adding 3 times of 95% ethanol of amount, 4 DEG C
24h, filtration are placed in refrigeration, and extract filter residue as far as possible, and filter residue adds 5 times of amount (w/v) secondary alcohol precipitations of absolute ethyl alcohol, same 4 DEG C
24h is placed in refrigeration, and filter residue is extracted in filtration as far as possible, 10 times of amount deionized water (w/v) dissolvings is added, as component 1.
B. shrubby sophora extract：Kuh-seng collects filtrate through water extraction, and concentration is obtained final product, used as component 2.
In above-mentioned steps b, it is preferred that shrubby sophora extract should be standby into meal, and the meal crosses 30-50 mesh sieves, then by kuh-seng
Meal and deionized water water extraction in proportion, its proportionate relationship are 1:15 (w/v), boil extraction 2 times, and each 1.5h collects and combines 2
Secondary extract solution, filtration, is concentrated into density 1.15 or so, as component 2.
C. the compound of glauber-salt and liquorice：It is commercially available prod, 2 times of water dissolves of quality is added, after filtering, as component 3.
In the present invention, in above-mentioned steps a, it is preferred that Ligusticum chuanxiong Hort should be prepared into meal, Ligusticum wallichii meal and deionized water ratio
Example, by 1:20 (w/v) ratios are added, and boil extraction 2 times, and each 1.5h collects and combines No. 2 extract solutions, and filtration is concentrated into density
1.10 or so.
Chinese medicine composition in the present invention, is according to prepared by above-mentioned all material rates and preparation method, then by each group
Divide well mixed.
Application of the above-mentioned Chinese medicine composition on skin acne removing agent is prepared.
In anti-acne skin preparations for extenal use of the invention, except above-mentioned Chinese traditional medicine composition beyond the region of objective existence, addition proper proportion can be needed to match somebody with somebody
The usually used matrix components of the skin care item of conjunction, such as propane diols, glycerine, Sodium Benzoate, xanthans, dimethyl silicone polymer.
The formulation of skin acne removing agent is not particularly limited, and can be solution, suspension, such as lotion；Can for emulsion,
Milk, such as milky lotion；Can be gel, paste, such as skin cream；Or all skin care item forms of facial mask etc..
The positive effect of the present invention is embodied in：
(1), the present invention is according to theory of traditional Chinese medical science, using the classics of Hospital Affiliated To Chengdu Traditional Chinese Medicine Univ Clinical practice for many years
Anti-acne side, it is improved to form.Wherein, the compound of glauber-salt and liquorice recovers qi and blood smoothness through clearing heat and detoxicating, repairs qi and blood and damages the acne skin long for causing
Skin is matt；Kuh-seng is effectively killed except the Propiobacterium, the acarid that are hidden in acne bottom as native insecticidal draft, and nonreactive
Raw element drug resistance phenomenon, while can be effectively antipruritic；Ligusticum wallichii recovers the ruddy gloss of acne print skin by promoting face's blood circulation.
Three taste medicine scientific compatibilities, disappear acne print so as to play anti-acne, and skin becomes smooth careful effect.
(2), three taste Chinese medicines in the present invention, preferred from source, it is ensured that the optimal efficacy of medicinal material.Wherein, Ligusticum wallichii is selected from this
Ten thousand mu of Ligusticum wallichii GAP planting bases of invention company, company location Sichuan Pengzhou is the Ligusticum wallichii genunie medicinal materials place of production, enjoys " Ligusticum wallichii
Township " good reputation；Kuh-seng produces genunie medicinal materials from Shanxi；The compound of glauber-salt and liquorice selects commercially available superior product, through physics and chemistry nature examination, heavy metal
Content meets national standard.Three taste Chinese medicines are prepared from through modern crafts.
(3), Chinese medicine composition of the invention and facial mask, effect are good, instant effect, and natural safety does not stimulate, through clinical test
Prove, each vaccination flesh, whelk, blackhead, hoary hair, acne, acne etc. on human body skin can be dispelled, while on face
Tubercle, tumour, useless fellow, papule are played and repair very well calm effect, recover the ruddy gloss of acne print skin.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to specific embodiment pair
The present invention is described in further detail, but this scope for being interpreted as above-mentioned theme of the invention should not be only limitted into following implementations
Example.
Embodiment 1：
A kind of preparation of Chinese medicine acne-removing composition, including, 0.2 part of Rhizoma Chuanxiong extract, 0.5 part of shrubby sophora extract, the compound of glauber-salt and liquorice
2.0 parts, mix, each raw material prepares as follows：
A. prepared by Rhizoma Chuanxiong extract：Ligusticum wallichii meal and deionized water, by 1:20 (w/v) ratios are added, and boil extraction 2 times,
Each 1.5h, collects and combines No. 2 extract solutions, filters, and is concentrated into density 1.10 or so.Filtrate is collected, 3 times of 95% second of amount are added
24h, filtration are placed in alcohol, 4 DEG C of refrigerations, and extract filter residue as far as possible, and filter residue adds 5 times of amount (w/v) secondary alcohol precipitations of absolute ethyl alcohol, together
24h is placed in 4 DEG C of refrigerations of sample, and filter residue is extracted in filtration as far as possible, 10 times of amount deionized water (w/v) dissolvings is added, as component 1.
B. shrubby sophora extract：Shrubby sophora extract should be prepared into meal, kuh-seng meal and deionized water ratio, by 1:15(w/
V) ratio is added, and boils extraction 2 times, and each 1.5h collects and combines No. 2 extract solutions, and filtration is concentrated into density 1.15 or so, makees
It is component 2.
C. the compound of glauber-salt and liquorice：It is commercially available prod, 2 times of water dissolves of quality is added, after filtering, as component 3.
Embodiment 2：
A kind of preparation of Chinese medicine acne-removing composition, wherein, 0.3 part of Rhizoma Chuanxiong extract, 0.8 part of shrubby sophora extract, the compound of glauber-salt and liquorice
2.1 parts, mix, each raw material is prepared and prepared by embodiment 1.
Embodiment 3：
A kind of preparation of Chinese medicine acne-removing composition, wherein, 0.5 part of Rhizoma Chuanxiong extract, 0.5 part of shrubby sophora extract, the compound of glauber-salt and liquorice
2.5 parts, each raw material is prepared and prepared by embodiment 1.
Embodiment 4：
Application of the Chinese medicine acne-removing composition in lotion, its raw material include the embodiment of the present invention 1 in Chinese medicine composition and
Corresponding cosmetic, each raw material is as follows based on 100 weight portions：
Chinese medicine composition (embodiment 1)：
0.2 part of Rhizoma Chuanxiong extract
0.5 part of shrubby sophora extract
2.0 parts of the compound of glauber-salt and liquorice
Matrix components：
Its preparation technology is：Above component is dissolved in deionized water and is fully mixed, sterilizing packing.
Embodiment 5：
Chinese medicine acne-removing composition gel sleep mask application, its raw material include the embodiment of the present invention 2 in Chinese medicine group
Compound and corresponding cosmetic, each raw material are as follows based on 100 weight portions：
Chinese medicine composition (embodiment 2)：
0.3 part of Rhizoma Chuanxiong extract
0.8 part of shrubby sophora extract
2.1 parts of the compound of glauber-salt and liquorice
Matrix components：
Its preparation technology is：
A. prepared by the embodiment of the present invention 2 comprising Rhizoma Chuanxiong extract, shrubby sophora extract, the Chinese medicine composition of the compound of glauber-salt and liquorice.
B. by xanthans addition deionized water, boiled in 70-85 DEG C of heating and be uniformly dissolved；
C. add sodium hyaluronate, Sodium Benzoate, xanthans, glycerine, propane diols, panthenol, vitamin E to be well mixed while hot, treat
When concentration ad pond om is total raw material 65% or so, stop heating；
D. after being cooled to room temperature, above-mentioned Chinese medicine composition is added, is well mixed, sterilizing packing.
Embodiment 6：
Application of the Chinese medicine acne-removing composition in skin cream, its raw material include the embodiment of the present invention 3 in Chinese medicine composition and
Corresponding cosmetic, each raw material is as follows based on 100 weight portions：
Chinese medicine composition (embodiment 3)：
0.5 part of Rhizoma Chuanxiong extract
0.5 part of shrubby sophora extract
2.1 parts of the compound of glauber-salt and liquorice
Matrix components：
Its preparation technology is：
A. card ripple, triethanolamine, butanediol, glycerine etc. are added in deionized water, stirring and dissolving, are heated to 85 DEG C,
20min sterilizings are maintained, water phase components 1 are made.
B. caprylic/capric triglyceride, dimethyl silicone polymer, cetostearyl alcohol olive oleate are mixed, continuous
Under stirring, 85 DEG C are heated to, are allowed to be dissolved into the liquid phase of homogeneous transparent, be made oil phase component 2.
C. in the case where being stirred continuously, component 2 is added in component 1,1min then is stirred vigorously with homogenizer, then slowly
Speed stirring, and slow cooling is cooled to 50 DEG C, adds Sodium Benzoate and Chinese medicine composition, is further continued for stirring and is cooled to room temperature i.e.
Can.
The Chinese medicine acne-removing composition prepared to embodiment 1-3, by 2015 editions《Chinese Pharmacopoeia》Four carry out physical and chemical index and
The detection of microbiological indicator, the results are shown in Table 1.
The Chinese medicine composition physical and chemical index of table 1
| Project | Index |
| Lead (in terms of pb) mg/kg≤ | 1.10 |
| Total arsenic (in terms of As) mg/kg≤ | 1.00 |
| Total mercury (in terms of Hg) mg/kg≤ | 0.22 |
The Chinese medicine composition microbiological indicator of table 2
| Project | Index |
| Total plate count cfu/g≤ | 100 |
| Coliform MPN/100g≤ | 22 |
| Mould cfu/g≤ | 17 |
| Yeast cfu/g≤2 | 15 |
| Pathogenic bacteria (salmonella, Shigella, staphylococcus aureus) | Without detection |
Testing result shows, in Chinese medicine composition obtained in the preparation method that the present invention is provided, reduces lead, total arsenic, total
The content of the heavy metals such as mercury, the content of lead is controlled within 1.1mg/kg, and the content of total arsenic is controlled within 1.10mg/kg,
The content of total mercury is controlled within 0.22mg/kg, and human body is had no toxic side effect, and microorganism indices reach qualified mark
It is accurate.
The evaluation of skin irritatin：
The present embodiment 4-6 Chinese medicine anti-acne skin conditioners are taken, is control with existing product, embodiment 4-6 is directly taken into appropriate painting
It is directly the border circular areas of 10mm to smear into, is right with autologous skin respective side in 80 Medial upper arm experiments of healthy men and women's property
According to per the bit test person of set product mapping 20, each 10 of men and women.Then, after 24 hours, skin is with the naked eye evaluated according to following standard
Skin situation, as a result see the table below.
Judging quota is：1. do not stimulate；2. minimal irritation；3. erythema；4. erythema and oedema；5. erythema, oedema and water
Bubble.
The Skin Irritation Test result of table 4
| Symptom number | Existing product | Embodiment 4 | Embodiment 5 | Embodiment 6 |
| Without stimulation | 19 | 20 | 20 | 19 |
| Minimal irritation | 1 | 0 | 0 | 1 |
| Erythema | 0 | 0 | 0 | 0 |
| Erythema and oedema | 0 | 0 | 0 | 0 |
| Erythema, oedema and bubble | 0 | 0 | 0 | 0 |
Result shows that in the present invention, embodiment 4,5 is nonirritant to human body skin, and 6 couples of 1 people of embodiment have slight thorn
Swash, show that Traditional Chinese medicine acne treatment mask of the invention is not less than existing product standard to skin irritation.
Clinical anti-acne effect test：
Anti acne of traditional Chinese medicine gel sleep mask C groups (contain Chinese medicine composition of the invention) obtained in 5 will be implemented, and A groups will be compareed
Gel sleep mask (containing only Rhizoma Chuanxiong extract) and control B group gels sleep mask (containing only the compound of glauber-salt and liquorice, shrubby sophora extract) control
Facial mask is contrasted, and carries out clinical trial.Wherein, control A group gel sleep masks with compare B group gels sleep mask preparation it is as follows：
Control A group gel sleep masks：Prepared by embodiment 5, the compound of glauber-salt and liquorice, shrubby sophora extract wherein in Chinese medicine composition
Substituted with the deionized water of homogenous quantities, be mixed with Rhizoma Chuanxiong extract and formed, remaining preparing raw material and the same embodiment of method
5。
Control B group gel sleep masks：Prepared by embodiment 5, the Rhizoma Chuanxiong extract homogeneity wherein in Chinese medicine composition
The deionized water of amount is substituted, and is mixed with the compound of glauber-salt and liquorice, shrubby sophora extract and formed, remaining preparing raw material and the same embodiment of method
5。
Testing crew：There were the patients with acne such as whelk, papule, useless fellow, tumour, acne at 300 ages at 15~30 years old
It is each about 60.It is divided into 3 groups, every group of 20 people or so, every group of men and women tries one's best respectively.
Application method is：Face is first cleaned up with water, takes the appropriate uniform application of this product in affected part, weekly using 2-3 times,
It is continuous to use more than 3 weeks.
Evaluation index：With inflammation improvement, skin gloss, anti-acne rate, (treatment acne points account for the percentage that total treatment acne is counted
Than), according to following criterion, the effective percentage for drawing, obvious effective rate are estimated, and result of the test see the table below.
Criterion：
(1) it is basic to cure：Skin is glossy, and inflammation disappears substantially, anti-acne rate ＞ 90%；
(2) it is effective：Skin is more glossy, and inflammation is obviously improved, anti-acne rate ＞ 60%；
(3) take a turn for the better：Skin slightly gloss, segmental inflammation improves, anti-acne rate ＞ 30%；
(4) it is invalid：The dark yellow improvement of skin, inflammation improves, anti-acne rate ＜ 30%.
Computing formula：
The clinical anti-acne effect test result of table 5
Result shows：By contrast, C groups of the present invention, more than 90%, average obvious effective rate are reached to acne average effectiveness level
66%, it is all remarkably higher than A groups, B groups；And by contrast, component C of the present invention is other to whelk, papule, useless fellow, tumour, 5 kinds of acne
The effective percentage of acne, obvious effective rate is also above A groups and B groups.The results show, prepared by the present invention contains Ligusticum wallichii, kuh-seng, profound
The Chinese medicine composition facial mask of bright powder has notable anti-acne advantage, and its scientific formulation, with synergy, is better than only addition wherein
Plant or two kinds of facial masks of the composition forms of Chinese medicine, and have remarkable result to various types of acnes.Additionally, C groups are suffered from acne
After being continuing with after person's removing acne, oil-control effect substantially, adjusts skin water and oil balance, and rebound phenomenon is reduced.
Additionally, follow-up study also shows, embodiment 4,6 is also acted on significant anti-acne, and effective to each vaccination flesh.
Be can be seen that according to above example, the micro- life of the anti-acne skin preparation of Chinese medicine composition of the invention and preparation, physics and chemistry
Thing index is up to state standards, and with the addition of the Chinese medicine anti-acne skin preparation of Chinese medicine composition of the present invention, can effectively dispel face
Acarid and anaerobic bacillus(cillus anaerobicus), treat both principal and secondary aspect of disease, effect is good, instant effect, natural safety, can dispel each vaccination flesh on human body skin,
Facial superior thyroid tubercle, tumour, useless fellow, papule is played simultaneously repair very well calm effect, recover the ruddy gloss of acne print skin.
Claims (6)
1. a kind of anti acne of traditional Chinese medicine composition, it is characterised in that the anti acne of traditional Chinese medicine composition by following weight portion bulk drug group
Into：
Rhizoma Chuanxiong extract 0.01-10 parts, shrubby sophora extract 0.01-20 parts, compound of glauber-salt and liquorice 1-8 parts.
2. Chinese medicine composition according to claim 1, it is characterised in that the weight of each bulk drug in the Chinese medicine composition
Part it is：
Rhizoma Chuanxiong extract 0.05-5 parts, shrubby sophora extract 0.1-5 parts, compound of glauber-salt and liquorice 2-5 parts.
3. Chinese medicine composition according to claim 1, it is characterised in that the weight of each bulk drug in the Chinese medicine composition
Part it is：
Rhizoma Chuanxiong extract 0.1-2 parts, shrubby sophora extract 0.1-3 parts, compound of glauber-salt and liquorice 2-4 parts.
4. a kind of preparation method of the Chinese medicine acne-removing composition as any one of claims 1 to 3, it is characterised in that described
The preparation method of Chinese medicine acne-removing composition is comprised the following steps：
It is prepared by a, Rhizoma Chuanxiong extract：Ligusticum chuanxiong Hort is first prepared into meal, then through water extraction, Ligusticum wallichii meal and deionized water ratio
Example, by 1:20（w/v）Ratio is added, and boils extraction 2 times, and each 1.5h collects and combines the extract solution of 2 times, and filtration is concentrated into close
Degree 1.10；Filtrate takes sediment fraction through alcohol precipitation, and deionized water dissolving obtains Rhizoma Chuanxiong extract；
B, shrubby sophora extract：Kuh-seng is first worn into meal, kuh-seng meal and deionized water are then pressed 1:15（w/v）Ratio adds
Enter, boil extraction 2 times, each 1.5h collects and combines No. 2 extract solutions, filtration is concentrated into density 1.15 and obtains shrubby sophora extract；
C, the compound of glauber-salt and liquorice：It is commercially available prod, 2 times of amount water dissolves is added, after filtering, as component 3.
5. the preparation method of Chinese medicine acne-removing composition according to claim 4, it is characterised in that：Alcohol precipitation in the step a
Refer to, by the filtrate after concentration, to add 3 times of volume 95wt% ethanol, 24 h, filtration are placed in 4 DEG C of refrigerations, and extract filter residue, are filtered
Slag adds 5 times of amounts（w/v）Absolute ethyl alcohol carries out secondary alcohol precipitation, and 24 h are placed in same 4 DEG C of refrigeration, and filter residue is extracted in filtration；It is described
Deionized water dissolving refer to add 10 times amount deionized waters（w/v）Dissolving.
6. application of the Chinese medicine composition according to claim 1-5 on skin acne removing agent is prepared.
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| CN107496267A (en) * | 2017-10-18 | 2017-12-22 | 佛山市飞时达新材料科技有限公司 | A kind of acne-eliminating cosmetic and preparation method thereof |
| CN108785196A (en) * | 2018-06-12 | 2018-11-13 | 北京明弘科贸有限责任公司 | A kind of composition for smoothing acne hole acne print and its application in cosmetics |
| CN112515999A (en) * | 2020-12-21 | 2021-03-19 | 阿谷巴(杭州)生物科技发展有限公司 | Mite and acne removing composition rich in cytokines and preparation method thereof |
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| CN1262113A (en) * | 1999-01-30 | 2000-08-09 | 秦贤汉 | Chinese-medicinal composition for treating acne |
| CN1927279A (en) * | 2006-09-06 | 2007-03-14 | 北京润德康医药技术有限公司 | Chinese medicine composition for treating skin disease |
| CN103202907A (en) * | 2012-01-11 | 2013-07-17 | 谭汉卿 | Improved traditional Chinese medicinal liniment for treating acnes |
| CN102600411A (en) * | 2012-04-12 | 2012-07-25 | 北京阳光一佰生物技术开发有限公司 | Composition for removing acne and preparation method |
| CN103041113A (en) * | 2013-01-22 | 2013-04-17 | 嘉兴萃清堂化妆品有限公司 | Plant compound gel for treating acne and preparation method thereof |
| CN104055944A (en) * | 2013-03-21 | 2014-09-24 | 李海波 | Traditional Chinese medicine composition capable of removing acne |
| CN104667045A (en) * | 2014-01-24 | 2015-06-03 | 潍坊医学院 | Medicine for treating refractory acne |
| CN104367817A (en) * | 2014-10-08 | 2015-02-25 | 景玲 | Chinese medicinal application for treating acne |
| CN105919890A (en) * | 2016-06-15 | 2016-09-07 | 广东芭薇生物科技股份有限公司 | Sebum-balancing acne-removing composition and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107496267A (en) * | 2017-10-18 | 2017-12-22 | 佛山市飞时达新材料科技有限公司 | A kind of acne-eliminating cosmetic and preparation method thereof |
| CN108785196A (en) * | 2018-06-12 | 2018-11-13 | 北京明弘科贸有限责任公司 | A kind of composition for smoothing acne hole acne print and its application in cosmetics |
| CN112515999A (en) * | 2020-12-21 | 2021-03-19 | 阿谷巴(杭州)生物科技发展有限公司 | Mite and acne removing composition rich in cytokines and preparation method thereof |
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