CN106614636A - Sterilization composition containing benziothiazolinone and flutolanil - Google Patents

Abstract

The invention discloses a bactericidal composition of thiamethoxam and fluoroamide. The bactericide composition is a dual compound compound of thiamethoxam and fluoroamide as active ingredients, and the weight ratio of thiamethoxam and fluoroamide is 1: 20～20:1. Add auxiliary agents and solvents to the active components of thiamethoxam and fluoroamide to prepare a hot fog agent, and the weight percentage of each component is: 1% to 20% of thiamethoxam and 1% to 20% of fluoroamide %, additives are 5% to 20%, and solvents make up to 100%. The composition of the present invention has a synergistic effect, and has good control effects on rice sheath blight, smut, melon and fruit blight, anthracnose, downy mildew, powdery mildew, etc., and not only reduces the The dosage of pesticides is reduced, and the cost of pesticides is also reduced, and the emergence of pesticide resistance is delayed.

Description

A kind of bactericidal composition of thiamethoxam and fluoroamide

technical field

The invention relates to the field of pesticides, in particular to a pesticide fungicide composition of thiamethoxam and fluoroamide.

Background technique

Benziothiazolinone (benziothiazolinone), its chemical name is 1,2 benzisothiazolin-3-one, its Chinese product name: YILIMIE, is a new type of broad-spectrum fungicide, which can prevent and treat fungal diseases effect. The chemical structural formula is:

Thiemmethadone has five characteristics: 1. High efficiency, 2. Low toxicity, 3. Broad spectrum, 4. Low residue, 5. Safe to use, 6. Dual functions of protection and eradication. The bactericidal mechanism of thiamethoxam mainly includes two aspects: destroying the nucleus structure of the bacteria, causing them to lose their heart and failing to die; Using it at the early stage of disease can effectively protect plants from pathogens, and increasing the dosage after disease occurs can obviously control the spread of pathogens, so as to achieve the dual functions of protection and eradication. It is mainly used to control cucumber downy mildew, pear scab, apple scab, citrus anthracnose, grape black pox, etc. It has special effects on various bacterial and fungal diseases.

Flutolanil, 3'-isopropoxy-2-(trifluoromethyl)benzanilide, the chemical structure is:

Fluoramide has strong systemic conduction and long-lasting effect, and it has a relatively good control effect on diseases caused by half-knowledge fungi and basidiomycetes, such as sheath blight, smut, and blight. Fluoramide mainly inhibits the activity of mitochondrial respiratory chain complex enzyme II (succinate-ubiquinone oxidoreductase, succinate-ubiquinone oxidoreductase) in pathogenic fungi, so that electrons cannot be transferred from succinate to ubiquinone, resulting in abnormal bacterial ATP synthesis, eventually leading to the death of the bacteria due to lack of energy.

At present, most of the existing thiamethoxam and fluoroamide are single doses. If the synergistic effect produced by mixing the two active components is used, the control effect can be improved, the spectrum of disease control can be expanded, the dosage of active ingredients can be reduced, and the cost of medication can be saved. , Delaying the emergence of pathogenic bacteria resistance, reducing environmental pollution, is an important means of comprehensive prevention and control of agricultural diseases.

Thermal mist, also known as aerosol, is a special oil that uses a high-boiling oily solvent as the dispersion medium for pesticide active ingredients and adds appropriate co-solvents and auxiliaries. When in use, with the help of a hot fog machine (note: a hot fog machine is also called a fog machine), this embodiment is quantitatively pressed into the smoke pipe, mixed with high-temperature and high-speed hot air and sprayed into the atmosphere to form a 1-10 μm Fog droplets spread and disperse in the field. After contacting crops or pests, they quickly adhere to the surface of crops or pests, and quickly penetrate into the interior to play a role in prevention and control.

Thermal mist has the following characteristics: 1. The mist droplets are extremely fine, evenly dispersed, and have good permeability, which improves the deposition of pesticides on target crops. 2. The dosage is less, which reduces the pollution of pesticides to the environment. 3. Long duration, strong adhesion to the target and strong resistance to rain erosion. 4. High efficiency, no need to add water, suitable for use in arid and water-deficient areas.

At present, there is no relevant report on the thermal mist compounded with thiamethoxamin and fluoroamide.

Contents of the invention

The object of the present invention is to provide a bactericidal composition of thiamethoxamin and fluoroamide, which not only expands the application range of each single agent under the optimal ratio combination formula synergism, but also ensures the optimal control effect and obvious synergy. Reduce the use of chemicals under certain circumstances, improve work efficiency and reduce costs.

Technical scheme of the present invention is as follows:

A bactericidal composition of thiamethoxam and fluoroamide is a two-component compound compound of thiamethoxam and fluoroamide as active ingredients, and the weight ratio of thiamethoxam and fluoroamide is 1:20-20:1.

As a preferred technical solution, the weight ratio of thiamethoxamin and fluoroamide is 1:10-10:1.

In the present invention, additives and solvents are added to the active components of thiamethoxam and fluoroamide to prepare a thermal mist, and the weight percentages between the components are: 1% to 20% of thiamethoxam and 1% of fluoroamide ～20%, the auxiliary agent is 5%～20%, and the solvent is supplemented to 100%.

The auxiliary agent that the present invention adopts comprises surfactant, synergist, penetration agent and flame retardant; Said surfactant is selected from fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, styrene ethylphenol polyoxyethylene ether A combination of one or more of oxyethylene ether and calcium dodecylbenzenesulfonate; the synergist is selected from one or both of butyrate and piperonyl butoxide; the penetrating agent One or two selected from thioketone and fast permeation T; the flame retardant is one of triphenyl phosphate, ammonium polyphosphate, aluminum hydroxide and brominated epoxy resin of phosphorus-based flame retardants or a combination of more than one.

The solvent used in the present invention is one or more combinations of aromatic solvents, vegetable oil solvents and polar solvents; aromatic solvents include trimethylbenzene, o-dichlorobenzene, tetramethylbenzene, diethylbenzene, methyl Naphthalene and secondary oils; vegetable oil solvents include cottonseed oil, rapeseed oil, castor oil, turpentine oil, and ethyl oleate; polar solvents include benzyl alcohol, dimethylsulfoxide, N,N-dimethylformamide, N, N-dimethylacetamide and ethylene glycol.

The preparation method of the hot mist agent of the present invention is: under normal temperature and pressure, in a mixing tank, the active component is completely dissolved in a solvent, and then other additives are added, and the stirring speed is 80-120 rpm , fully stirred for 30-60 minutes to make it evenly mixed, and then the hot mist dosage form was obtained.

The fungicidal composition of thiamethoxam and fluoroamide of the present invention can be used in the control of crop pests such as rice, melons and fruits, fruit trees and forest trees. Suitable target crops are rice, cucumber, apple, pear, citrus, grape, corn, cotton, rubber tree, macadamia tree, eucalyptus and the like. For rice sheath blight, smut, melon and fruit blight, anthracnose, downy mildew, powdery mildew, etc. have a good control effect.

The bactericidal composition of the present invention is prepared as a hot mist, sprayed with a hot mist machine, and used in a targeted manner according to the disease situation, and the usual dosage is 1L-5L/hm ² .

The beneficial effects of the present invention are:

1. In the present invention, thiamethoxamin and fluoroamide with different action mechanisms are compounded, so that they can realize the complementarity of the agents, prolong the service life of each single agent, and delay the generation of pathogenic bacteria resistance.

2. The present invention has the characteristics of high efficiency, less dosage, and less environmental hazards. It shows a significant synergistic effect within a certain proportion range. Compared with a single agent, the control effect is significantly improved, and the use dose of pesticides is reduced. It also reduces the cost of medication.

3. The bactericidal composition of the present invention is prepared into a thermal mist, which has high work efficiency, and can be applied with a thermal mist machine, with low labor intensity, low cost, greatly improved efficiency, reduced drug cost, good quick effect, and outstanding control effect.

4. The bactericidal composition of the present invention expands the bactericidal spectrum, and the control range is wider, especially in the prevention and treatment of melons, fruit tree powdery mildew, blight, downy mildew, anthracnose, rice blight, rice sheath blight, etc. It has a good control effect on diseases.

detailed description

The invention is illustrated by the following examples, which do not limit the scope of the invention.

Example 1

21% Thiadyramulone Fluoramide Germicidal Hot Fog (Thimethidone: Fluoramide = 1:20)

Formula: thiamethoxamil 1kg, fluoroamide 20kg, alkylphenol polyoxyethylene ether 4kg, calcium dodecylbenzenesulfonate 3.5kg, dimethyl sulfoxide 5kg, N,N-dimethylacetamide 5kg, bromide Epoxy resin 0.5kg, methyl naphthalene supplemented to 100kg.

Preparation method: at normal temperature and pressure, put thiamethondone, fluoroamide and solvent into a stirring tank, and at a stirring speed of 100-120 rpm, dissolve thiamethoxamidone and fluoroamide in the solvent, then add additives, fully Stir for 30 to 40 minutes to make it evenly mixed to obtain 21% thiamethondone·fluamide bactericidal thermal spray.

Example 2

16% Thiadyramulone Fluoramide Sterilizing Hot Fog (Thimethidone: Fluoramide = 1:15)

Formula: thiamethoxam ketone 1kg, fluoroamide 15kg, phenethylphenol polyoxyethylene ether 4kg, calcium dodecylbenzenesulfonate 2kg, triphenyl phosphate 2kg, thiophene 2kg, dimethyl sulfoxide 10kg, N, N - Dimethylformamide 15kg, aluminum hydroxide 0.5kg, trimethylbenzene make up to 100kg.

Preparation method: at normal temperature and pressure, put thiamethondone, fluoroamide and solvent into a stirred tank, and at a stirring speed of 80-100 rpm, dissolve thiamethoxamidone and fluoroamide in the solvent, and then add additives , fully stirred for 40 to 60 minutes to make it evenly mixed to obtain 16% thiamethoxamyl flunamide bactericidal thermal spray.

Example 3

22% Thiadyramulone Fluoramide Sterilizing Thermal Fog (Thimethidone: Fluoramide = 1:10)

Formula: 2kg thiamethoxam, 20kg fluoroamide, 3kg alkylphenol polyoxyethylene ether, 1kg calcium dodecylbenzene sulfonate, 0.5kg rapid permeation T, 0.5kg brominated epoxy resin, 15kg dimethyl sulfoxide, Benzyl alcohol 10kg, turpentine make up to 100kg.

Preparation method: at normal temperature and pressure, put thiamethondone, fluoroamide and solvent into a stirred tank, and at a stirring speed of 90-110 rev/min, dissolve thiamethondone and fluoroamide in the solvent, and then add additives , fully stirred for 40 to 50 minutes to make it evenly mixed, and then 22% thiamethoxamyl flunamide bactericidal thermal spray was obtained.

Example 4

12% thiamethoxam·fluamide bactericidal thermal mist (thiamethoxam:fluamide=1:5)

Formula: 2kg thiamethoxam, 10kg fluoroamide, 7kg phenylethylphenol polyoxyethylene ether, 8kg calcium dodecylbenzenesulfonate, 1.5kg ammonium polyphosphate, 2kg thiazide, 1.5kg aluminum hydroxide, dimethyl methoxide Sulfone 8kg, ethylene glycol 10kg, rapeseed oil make up to 100kg.

Preparation method: at normal temperature and pressure, put thiamethondone, fluoroamide and solvent into a stirring tank, and at a stirring speed of 100-120 rpm, dissolve thiamethoxamidone and fluoroamide in the solvent, and then add additives , fully stirred for 50 to 60 minutes to make it evenly mixed to obtain 12% thiamethoxamyl flunamide bactericidal thermal mist.

Example 5

16% Thiadyramulone Fluoramide Germicidal Thermal Fog (Thimethidone: Fluoramide = 1:1)

Formula: thiamethoxam ketone 8kg, fluoroamide 8kg, alkylphenol polyoxyethylene ether 5kg, calcium dodecylbenzene sulfonate 3kg, piperonyl butoxide 1kg, thiophene 2kg, dimethyl sulfoxide 15kg, tetramethylbenzene 10kg, Cottonseed oil supplemented to 100kg.

The preparation method is the same as in Example 1.

Example 6

18% thiamethinone·fluamide bactericidal thermal spray (thiamethoxam:fluamide=5:1)

Formula: thiamethoxamone 15kg, fluoroamide 3kg, fatty alcohol polyoxyethylene ether 5kg, calcium dodecylbenzenesulfonate 2.5kg, triphenyl phosphate 3kg, fast osmosis T 2kg, cottonseed oil 10kg, ammonium polyphosphate 0.4kg , Diethylbenzene is added to 100kg.

The preparation method is the same as in Example 1.

Example 7

13.5% thiamethonin · fluoramide bactericidal hot spray (thiamethonin: fluoramide = 8:1)

Formula: thiamethoxamone 12kg, fluoroamide 1.5kg, fatty alcohol polyoxyethylene ether 4kg, calcium dodecylbenzenesulfonate 4kg, triphenyl phosphate 3kg, fast osmosis T2kg, o-dichlorobenzene 10kg, brominated epoxy Resin 0.4kg, second-line oil to make up to 100kg.

The preparation method is the same as in Example 1.

Example 8

16.5% thiamethonin · fluoramide bactericidal hot spray (thiamethonin: fluoramide = 10:1)

Formula: 15kg of thiamethoxam, 1.5kg of fluoroamide, 2kg of phenylethylphenol polyoxyethylene ether phosphate, 2.5kg of calcium dodecylbenzenesulfonate, 12kg of dimethyl sulfoxide, 0.3kg of aluminum hydroxide, turpentine to make up to 100kg.

The preparation method is the same as in Example 1.

Example 9

19.2% thiamethonin · fluoramide bactericidal hot spray (thiamethonin: fluoramide = 15:1)

Formula: 18kg thiamethoxam, 1.2kg fluoroamide, 4kg alkylphenol polyoxyethylene ether, 2.5kg calcium dodecylbenzenesulfonate, 3kg triphenyl phosphate, 10kg dimethyl sulfoxide, 0.5 brominated epoxy resin kg, make up to 100kg with ethyl oleate.

The preparation method is the same as in Example 1.

Example 10

21% Thiadyramulone Fluoramide Sterilizing Thermal Fog (Thimethidone: Fluoramide = 20:1)

Formula: 20kg of thiamethoxamil, 1kg of fluoroamide, 8kg of fatty alcohol polyoxyethylene ether, 2kg of calcium dodecylbenzenesulfonate, 2kg of synergistic phosphorus, 0.2kg of triphenyl phosphate, and castor oil to make up to 100kg.

The preparation method is the same as in Example 1.

Application example

The beneficial effects of the present invention are further illustrated by the following field tests.

Experimental example 1:

Table 1 shows the results of the toxicity test of the thiamethoxam-fluamide composition.

When CTC≤80, the composition exhibits antagonistic effect; when 80<CTC<120, the composition exhibits additive effect; when CTC≥120, the composition exhibits synergistic effect.

Table 1 Toxicity determination of different ratios of thiamethoxam and fluoramide against rice sheath blight

It can be seen from Table 1 that when the ratio of thiamethoxamin to fluoroamide is between 20:1 and 1:20, the co-toxicity coefficients are all greater than 150, indicating that the combination of thiamethoxamin and fluoroamide exhibits obvious synergistic effect.

Test example 2: field test of controlling rice sheath blight.

Application site: a rice planting experiment site in Chongzuo City, Guangxi

Together with the blank control, 13 treatments were set up in the test, each treatment was repeated 3 times, a total of 39 plots, each plot was randomly arranged, and the investigation was carried out 7 days and 14 days after the drug;

Table 2 Control effect of thiamethoxam·fluamide bactericidal thermal mist on rice sheath blight

Test drug Active ingredient dosage (g/mu) 7 days after drug control effect (%) 14 days after drug control effect (%) Example 1 50 92.5 95.6 Example 2 40 89.8 93.5 Example 3 55 93.6 97.8 Example 4 30 88.7 92.8 Example 5 40 92.2 96.3 Example 6 50 93.5 97.2 Example 7 35 86.5 89.8 Example 8 40 92.5 94.4 Example 9 50 94.3 96.6 Example 10 50 90.0 93.6 40% Fluoramide SC 50 76.5 79.3 1.5% Thiprofen EW 50 72.3 78.9

As can be seen from the test results in Table 2, 7 days after application, the control effect of the thiamethoxamin·fluamide fungicidal composition on rice sheath blight was above 85%, which was significantly higher than that of each single-dose control agent; The preventive effects of the compositions were all over 90%, which was also significantly higher than that of each single-dose control drug, and the combination had a synergistic effect.

Claims (7)

1. the bactericidal composition of a kind of benziothiazolinone and flutolanil, it is characterised in that：The microbicide compositions are with benziothiazolinone and fluorine Acid amides is compounded for the two-spot that active ingredient is carried out, and the weight ratio of benziothiazolinone and flutolanil is 1:20～20:1.

2. the bactericidal composition of benziothiazolinone according to claim 1 and flutolanil, it is characterised in that：Benziothiazolinone and flutolanil Weight ratio be 1:10～10:1.

3. the bactericidal composition of benziothiazolinone according to claim 1 and 2 and flutolanil, it is characterised in that：In benziothiazolinone and Auxiliary agent and solvent is added to be prepared into thermal fog in the active component of flutolanil, the weight percentage between each component is：Benziothiazolinone 1%～20%, flutolanil is 1%～20%, and auxiliary agent is 5%～20%, and solvent complements to 100%.

4. the bactericidal composition of benziothiazolinone according to claim 3 and flutolanil, it is characterised in that：The auxiliary agent includes table Face activating agent, synergist, bleeding agent and fire retardant；The surfactant is selected from AEO, alkyl phenol polyoxy One or more combination in vinethene, phenethyl phenol polyethenoxy ether and calcium dodecyl benzene sulfonate；The synergy Agent is selected from one or two in Synergistic Phosphorus and piperonyl butoxide；The bleeding agent is selected from thiophene ketone and oozes the one kind in T or two soon Kind；The fire retardant is the one kind in triphenyl phosphate, APP, aluminium hydroxide and the brominated epoxy resin of phosphorus flame retardant Or more than one combination.

5. the bactericidal composition of benziothiazolinone according to claim 3 and flutolanil, it is characterised in that：The solvent is aromatic hydrocarbons One or more combination in class solvent, plant oil solvent and polar solvent；Aromatic hydrocarbon solvent includes trimethylbenzene, neighbour Dichloro-benzenes, durene, diethylbenzene, methyl naphthalene and two wires oil；Plant oil solvent includes cottonseed oil, rapeseed oil, castor oil, turpentine Oil and ethyl oleate；Polar solvent include phenmethylol, dimethyl sulfoxide, DMF, DMA and Ethylene glycol.

6. the bactericidal composition of benziothiazolinone according to claim 3 and flutolanil, it is characterised in that：The system of the thermal fog Preparation Method is：Under normal temperature and pressure, in mixing kettle, after active component is first completely dissolved with solvent, other auxiliary agents are added, Mixing speed obtains final product thermal fog type under 80～120 revs/min, to be sufficiently stirred for 30～60 minutes so as to be well mixed.

7. a kind of application of the bactericidal composition of the benziothiazolinone and flutolanil as described in claim 1 to 6 is arbitrary, its feature exists In：Its application in preventing and treating paddy rice, melon and fruit, fruit tree and forest crop insect.