CN105941426B - 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 - Google Patents
一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 Download PDFInfo
- Publication number
- CN105941426B CN105941426B CN201610588357.5A CN201610588357A CN105941426B CN 105941426 B CN105941426 B CN 105941426B CN 201610588357 A CN201610588357 A CN 201610588357A CN 105941426 B CN105941426 B CN 105941426B
- Authority
- CN
- China
- Prior art keywords
- ethyl ketone
- adipic acid
- acid copper
- pyrrole ethyl
- thiazole pyrrole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 239000003292 glue Substances 0.000 title claims abstract description 28
- ZCXLQZOQWCXFNN-UHFFFAOYSA-N copper;hexanedioic acid Chemical compound [Cu].OC(=O)CCCCC(O)=O ZCXLQZOQWCXFNN-UHFFFAOYSA-N 0.000 title claims abstract description 27
- 239000000203 mixture Substances 0.000 title claims abstract description 24
- 241000282376 Panthera tigris Species 0.000 title claims abstract description 18
- 239000000575 pesticide Substances 0.000 title description 8
- IPPZJWGYHAMLAB-UHFFFAOYSA-N C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1 Chemical compound C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1 IPPZJWGYHAMLAB-UHFFFAOYSA-N 0.000 title description 4
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 title description 4
- 229910052731 fluorine Inorganic materials 0.000 title description 4
- 239000011737 fluorine Substances 0.000 title description 4
- FXYOBYMJDLKKMF-UHFFFAOYSA-N C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1.[F] Chemical compound C(C)C(=O)CC.N1C=CC=C1.S1C=NC=C1.[F] FXYOBYMJDLKKMF-UHFFFAOYSA-N 0.000 claims abstract description 23
- 241000233679 Peronosporaceae Species 0.000 claims abstract description 11
- 230000000844 anti-bacterial effect Effects 0.000 claims description 8
- 239000000470 constituent Substances 0.000 claims description 8
- 230000002195 synergetic effect Effects 0.000 abstract description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 201000010099 disease Diseases 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 7
- 238000012360 testing method Methods 0.000 description 7
- 239000003814 drug Substances 0.000 description 6
- 239000004563 wettable powder Substances 0.000 description 6
- 230000000694 effects Effects 0.000 description 5
- 230000000855 fungicidal effect Effects 0.000 description 5
- 239000000417 fungicide Substances 0.000 description 5
- -1 for example Substances 0.000 description 4
- 244000052769 pathogen Species 0.000 description 4
- 230000001717 pathogenic effect Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 3
- 238000013329 compounding Methods 0.000 description 3
- 239000010949 copper Substances 0.000 description 3
- 229910052802 copper Inorganic materials 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 230000003449 preventive effect Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000000375 suspending agent Substances 0.000 description 3
- IAQLCKZJGNTRDO-UHFFFAOYSA-N 1-(4-{4-[5-(2,6-difluorophenyl)-4,5-dihydro-1,2-oxazol-3-yl]-1,3-thiazol-2-yl}piperidin-1-yl)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]ethanone Chemical compound CC1=CC(C(F)(F)F)=NN1CC(=O)N1CCC(C=2SC=C(N=2)C=2CC(ON=2)C=2C(=CC=CC=2F)F)CC1 IAQLCKZJGNTRDO-UHFFFAOYSA-N 0.000 description 2
- 239000005995 Aluminium silicate Substances 0.000 description 2
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- 235000012211 aluminium silicate Nutrition 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 229920005551 calcium lignosulfonate Polymers 0.000 description 2
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 2
- 229910001431 copper ion Inorganic materials 0.000 description 2
- YDEXUEFDPVHGHE-GGMCWBHBSA-L disodium;(2r)-3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Na+].[Na+].COC1=CC=CC(C[C@H](CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O YDEXUEFDPVHGHE-GGMCWBHBSA-L 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 239000003337 fertilizer Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 description 2
- 244000039328 opportunistic pathogen Species 0.000 description 2
- FDPIMTJIUBPUKL-UHFFFAOYSA-N pentan-3-one Chemical compound CCC(=O)CC FDPIMTJIUBPUKL-UHFFFAOYSA-N 0.000 description 2
- 229940051841 polyoxyethylene ether Drugs 0.000 description 2
- 229920000056 polyoxyethylene ether Polymers 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- BOMXNVKTSSSTNJ-UHFFFAOYSA-N C1CC=NO1.C1CCN(CC1)c1nccs1 Chemical class C1CC=NO1.C1CCN(CC1)c1nccs1 BOMXNVKTSSSTNJ-UHFFFAOYSA-N 0.000 description 1
- 208000031968 Cadaver Diseases 0.000 description 1
- 241000207199 Citrus Species 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000010799 Cucumis sativus var sativus Nutrition 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- VUQWAFLIERLCBD-UHFFFAOYSA-N N1C=CC=C1.S1C=NC=C1.[F] Chemical compound N1C=CC=C1.S1C=NC=C1.[F] VUQWAFLIERLCBD-UHFFFAOYSA-N 0.000 description 1
- RCEAADKTGXTDOA-UHFFFAOYSA-N OS(O)(=O)=O.CCCCCCCCCCCC[Na] Chemical compound OS(O)(=O)=O.CCCCCCCCCCCC[Na] RCEAADKTGXTDOA-UHFFFAOYSA-N 0.000 description 1
- 241000233654 Oomycetes Species 0.000 description 1
- 239000005812 Oxathiapiprolin Substances 0.000 description 1
- 241000233622 Phytophthora infestans Species 0.000 description 1
- 241001281803 Plasmopara viticola Species 0.000 description 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- FZWLAAWBMGSTSO-UHFFFAOYSA-N Thiazole Chemical group C1=CSC=N1 FZWLAAWBMGSTSO-UHFFFAOYSA-N 0.000 description 1
- 235000009754 Vitis X bourquina Nutrition 0.000 description 1
- 235000012333 Vitis X labruscana Nutrition 0.000 description 1
- 240000006365 Vitis vinifera Species 0.000 description 1
- 235000014787 Vitis vinifera Nutrition 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 239000003899 bactericide agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- MGIWDIMSTXWOCO-UHFFFAOYSA-N butanedioic acid;copper Chemical compound [Cu].OC(=O)CCC(O)=O MGIWDIMSTXWOCO-UHFFFAOYSA-N 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 210000000170 cell membrane Anatomy 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 235000020971 citrus fruits Nutrition 0.000 description 1
- 230000001112 coagulating effect Effects 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- LMCVMQNMDSVUFJ-UHFFFAOYSA-N copper;pentanedioic acid Chemical compound [Cu].OC(=O)CCCC(O)=O LMCVMQNMDSVUFJ-UHFFFAOYSA-N 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 239000002552 dosage form Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- NVVZQXQBYZPMLJ-UHFFFAOYSA-N formaldehyde;naphthalene-1-sulfonic acid Chemical compound O=C.C1=CC=C2C(S(=O)(=O)O)=CC=CC2=C1 NVVZQXQBYZPMLJ-UHFFFAOYSA-N 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 230000009036 growth inhibition Effects 0.000 description 1
- 230000002363 herbicidal effect Effects 0.000 description 1
- 239000004009 herbicide Substances 0.000 description 1
- GPRLSGONYQIRFK-UHFFFAOYSA-N hydron Chemical compound [H+] GPRLSGONYQIRFK-UHFFFAOYSA-N 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 239000002917 insecticide Substances 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 125000000842 isoxazolyl group Chemical group 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 231100001231 less toxic Toxicity 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 239000004530 micro-emulsion Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- ZQSIWEQDNMDSMV-UHFFFAOYSA-N pentan-3-one 1H-pyrrole Chemical compound C(C)C(=O)CC.N1C=CC=C1 ZQSIWEQDNMDSMV-UHFFFAOYSA-N 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 239000003090 pesticide formulation Substances 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 229910001414 potassium ion Inorganic materials 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 125000003226 pyrazolyl group Chemical group 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- 239000004562 water dispersible granule Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
- A01N37/04—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof polybasic
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
本发明公开了一种含有氟噻唑吡乙酮和琥胶肥酸铜的组合物，所述组合物中氟噻唑吡乙酮和琥胶肥酸铜的重量比为1:30‑30：1，优选为1:10‑10：1，本发明的组合物对葡萄霜霉病在所述的配比范围内表现出较好的增效作用。
Description
技术领域
本发明涉及农药组合物领域，具体涉及的是一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物。
背景技术
霜霉病、晚疫病是危害蔬菜水果类作物的严重病害。据调查数据，在欧洲，每年价值1.8亿欧元的农药用于防治霜霉病。而全球每年因马铃薯晚疫病造成的经济损失高达40亿欧元。
氟噻唑吡乙酮，英文通用名oxathiapiprolin，CAS登录号1003318-67-9，化学名称1-(4-{4-[(5RS)-5-(2,6-二氟苯基)-4,5-二氢-1,2-噁唑-3-基]-1,3-噻唑-2-基}-1-哌啶基)-2-[5-甲基-3-(三氟甲基)-1H-吡唑-1-基]乙酮，是杜邦于近期推出的具有全新作用机理的杀菌剂氟噻唑吡乙酮则堪称防治霜霉病和晚疫病的划时代产品。氟噻唑吡乙酮是杜邦公司新研发的首个哌啶基噻唑异噁唑啉类杀菌剂，其结构包括异噁唑环、吡唑环和噻唑环。这款产品从发现到上市历时14年，凝聚了杜邦科学家们的杰出智慧。该杀菌剂对卵菌纲病原菌具有独特的作用位点，对马铃薯、葡萄、蔬菜和其他特色农作物的霜霉病和疫病具有卓越防效。
琥胶肥酸铜，英文名称：copper，为丁二酸铜、戊二酸铜、己二酸铜的混合物，属于有机铜杀菌剂，琥胶肥酸铜主要通过铜离子与病原菌膜表面的钾离子、氢离子等交换，使病原菌细胞膜上蛋白质凝固，同时部分铜离子渗透到病原菌细胞内与某些酸结合，影响酶的活性，起到杀菌作用，对黄瓜细菌性角斑病，柑橘溃疡病等效果好。
不同农药品种成分进行复配，是防治农作物病害抗性产生的有效途径，开发与研究高效、低毒、低残留的复配制剂具有投资少、研发周期短的优点，因而受到国内外研发机构的重视。本申请的发明人在室内筛选和田间药效试验的基础上，筛选出氟噻唑吡乙酮与琥胶肥酸铜进行复配，在一定的范围内对葡萄霜霉病具有明显的增效作用。目前，尚无关于氟噻唑吡乙酮与琥胶肥酸铜复配的报道。
发明内容
本发明的目的在于提供一种适合农业上使用的增效杀菌组合物，有助于减少农药使用量、延缓病原菌抗药性的产生。
为解决上述技术问题，本发明采用如下技术方案：一种杀菌组合物，其特征在于，活性成分包括氟噻唑吡乙酮和琥珀胶肥酸铜，所述活性成分的质量比为1:30-30:1，优选为1:10-10：1。
进一步的，所述杀菌组合物中活性成分的重量比为1-90%，优选为20-60%。
进一步的，本发明的杀菌组合物可以通过农药直接加工中常规的制备方法制备成为农药制剂加工中的任意一种剂型，例如可以是乳油、可湿性粉剂、悬浮剂、水分散粒剂、水乳剂、微乳剂、颗粒剂等。
本发明的组合物可以以成品制剂形式提供即组合物中各物质已经混合，也可以以单剂形式提供，使用前直接在桶或罐中按比例混合，然后稀释至所需要的浓度。
进一步的，本发明的组合物还可以加入其它农用活性成分，例如杀菌剂、杀虫剂、除草剂、肥料等农用活性成分。
本发明的杀菌组合物适用于防除农作物霜霉病、晚疫病等。
与现有技术相比，本发明的有益效果为：
（1）本发明的组合物复配后，在一定的范围内具有明显的协同增效作用，防效与单个活性成分相比有明显的提高；
（2）本发明的组合物中活性成分作用机理各不相同，在有效防治作物病害的同时，可以延缓病原菌抗药性的产生，有利于延缓农药活性成分的使用寿命，进一步降低了生产成本和使用成本，有利于抗性病害的综合防治；
（3）本发明的组合物制备工艺简单，适合实际生产中推广应用。
具体实施方式
为了使本发明的本发明的目的、技术方案及优点更加清楚明白，本发明用以下具体实施例进行说明，但本发明绝非限于这些例子。以下所述仅为本发明较好的实施例，仅仅用于解释本发明，但不能因此理解为对本发明专利范围的限制。应当指出的是，凡在本发明的精神和原则之内所作的任何修改、等同替换或改进等，均应包含在本发明的保护范围之内，因此，本发明专利的保护范围应以所附权利要求为准。
一、制剂实施例
1、实施例1:21%氟噻唑吡乙酮·琥珀胶肥酸铜可湿性粉剂（20:1）
氟噻唑吡乙酮 20%
琥胶肥酸铜 1%
木质素磺酸钠 3%
十二烷基硫酸钠 4%
白炭黑 5%
硅藻土 余量
2、实施例2:11%氟噻唑吡乙酮·琥珀胶肥酸铜水分散粒剂（10：1）
氟噻唑吡乙酮 10%
琥胶肥酸铜 1%
木质素磺酸钙 3%
硫酸铵 2%
烷基酚聚氧乙烯醚硫酸盐 3%
羟甲基纤维素 2%
高岭土 余量
3、实施例3:30%氟噻唑吡乙酮·琥珀胶肥酸铜悬浮剂（1:1）
氟噻唑吡乙酮 15%
琥胶肥酸铜 15%
脂肪醇聚氧乙烯醚 8%
木质素磺酸钠 7%
黄原胶 2%
有机硅酮 2%
苯甲酸钠 0.2%
乙二醇 0.5%
去离子水 余量
4、实施例4:33%氟噻唑吡乙酮·琥珀胶肥酸铜可湿性粉剂（1：10）
氟噻唑吡乙酮 3%
琥胶肥酸铜 30%
萘磺酸盐甲醛缩合物 6%
木质素磺酸钙 4%
拉开粉 5%
高岭土 余量
二、室内毒力测定
试验对象：葡萄霜霉病菌
试验方法：经预试确定氟噻唑吡乙酮和琥胶肥酸铜的有效抑制浓度后，设置两种药剂不同浓度梯度，参照《农药室内生物测定试验准则杀菌剂》进行，采用菌丝生长速率法测定药剂对作物病菌的毒力，72 h后用十字交叉法测量菌落直径，计算各处理净生长量，菌丝生长抑制率。防治效果换算成机率值（y）,药液浓度（ug/mL）转换成对数值（x）,以最小而乘法计算毒力方程和抑制中浓度EC50，依孙云沛法计算药剂的毒力指数及共毒系数（CTC）。试验结果见表1。
由表1中的测定结果可以看出，氟噻唑吡乙酮与琥胶肥酸铜胺重量比为1:30-30:1的范围内复配对葡萄霜霉病的CTC值均在120以上，表现出增效作用；其中，当组合物中活性成分重量比为1:20-20：1时，各处理的CTC值均在140以上，协同增效作用更显著。
三、田间药效试验
为进一步验证本发明的实际应用效果，采用本发明实施例的药剂进行葡萄霜霉病田间药效试验。
供试药剂：（1）21%氟噻唑吡乙酮·琥珀胶肥酸铜可湿性粉剂；（2）11%氟噻唑吡乙酮·琥珀胶肥酸铜水分散粒剂；（3）30%氟噻唑吡乙酮·琥珀胶肥酸铜悬浮剂；（4）33%氟噻唑吡乙酮·琥珀胶肥酸铜可湿性粉剂；（5）对比例1:10%氟噻唑吡乙酮乳油；（6）30%琥胶肥酸铜可湿性粉剂。
分别于药后5天、10天调查病情指数并计算防效，试验结果见表2。
田间药效试验结果表明，氟噻唑吡乙酮与琥胶肥酸铜的复配制剂对葡萄霜霉病的防治表现出较好的持效性和速效性，明显由于单个活性成分的制剂防治效果，且在用药范围内，未发现所述组合物制剂对作物产生药害，表明本发明的组合物安全性也较好，值得在生产上推广应用。
Claims (2)
1.一种杀菌组合物，其特征在于，活性成分包含氟噻唑吡乙酮和琥胶肥酸铜，其中，氟噻唑吡乙酮与和琥胶肥酸铜的重量比为1:30-30:1。
2.根据权利要求1所述的杀菌组合物用于防治葡萄霜霉病的应用。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610588357.5A CN105941426B (zh) | 2016-07-25 | 2016-07-25 | 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610588357.5A CN105941426B (zh) | 2016-07-25 | 2016-07-25 | 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105941426A CN105941426A (zh) | 2016-09-21 |
| CN105941426B true CN105941426B (zh) | 2018-11-02 |
Family
ID=56900321
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610588357.5A Active CN105941426B (zh) | 2016-07-25 | 2016-07-25 | 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105941426B (zh) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107950543A (zh) * | 2017-12-10 | 2018-04-24 | 广东中迅农科股份有限公司 | 一种含有噻霉酮和氟噻唑吡乙酮的杀菌组合物 |
| CN108294047A (zh) * | 2018-02-02 | 2018-07-20 | 深圳诺普信农化股份有限公司 | 一种含有氟噻唑吡乙酮的杀菌组合物及其应用 |
| CN108719308A (zh) * | 2018-08-19 | 2018-11-02 | 安徽嘉联生物科技有限公司 | 一种含氟噻唑吡乙酮和琥胶肥酸铜的杀菌组合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI428091B (zh) * | 2007-10-23 | 2014-03-01 | Du Pont | 殺真菌劑混合物 |
| CN104336023A (zh) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | 一种含氟噻唑吡乙酮的杀菌组合物 |
| CN104521988B (zh) * | 2014-12-18 | 2016-08-24 | 广西田园生化股份有限公司 | 一种含甲磺酰菌唑和琥胶肥酸铜的复配组合物及制剂 |
-
2016
- 2016-07-25 CN CN201610588357.5A patent/CN105941426B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN105941426A (zh) | 2016-09-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN101632364A (zh) | 杀菌组合物 | |
| CN105961406A (zh) | 一种含氟噻唑吡乙酮和喹啉铜的农药组合物 | |
| CN105941426B (zh) | 一种含氟噻唑吡乙酮和琥胶肥酸铜的农药组合物 | |
| CN106234388B (zh) | 一种含苯并烯氟菌唑和小檗碱的农药组合物 | |
| CN109362759A (zh) | 一种含氯氟醚菌唑和吡唑醚菌酯的杀菌组合物及其应用 | |
| CN106172433A (zh) | 一种含氟噻唑吡乙酮和氨基寡糖素的农药组合物 | |
| CN109463384A (zh) | 一种含百里香酚和啶酰菌胺的杀菌组合物 | |
| CN106234377B (zh) | 一种含氟噻唑吡乙酮和丁子香酚的复配组合物 | |
| CN106035346A (zh) | 一种含氟噻唑吡乙酮和乙蒜素的杀菌组合物 | |
| CN103651452A (zh) | 一种含辛菌胺和多菌灵的杀菌组合物及应用 | |
| CN114097827B (zh) | 一种杀菌剂组合物、制备方法以应用 | |
| CN104886122B (zh) | 含毒氟磷和吡唑酰胺类杀菌剂的复配组合物及杀菌剂 | |
| CN102846489B (zh) | 一种盐酸聚六亚甲基胍碘药浴液及其制备方法 | |
| CN106234389A (zh) | 一种含氟噻唑吡乙酮和小檗碱的农药组合物 | |
| CN106561677A (zh) | 一种含二氯噁菌唑和氨基寡糖素的农药组合物及其应用 | |
| CN106212476A (zh) | 一种含氟噻唑吡乙酮和松脂酸铜的杀菌组合物 | |
| CN108605948A (zh) | 一种含有氟噻唑吡乙酮与吲唑磺菌胺的杀菌组合物 | |
| CN103651440A (zh) | 一种复配杀菌剂 | |
| CN106508911B (zh) | 一种含嘧菌环胺和氨基寡糖素的杀菌组合物 | |
| CN114847292B (zh) | 一种含有苯酰菌胺和咯菌腈的杀菌组合物及其用途 | |
| CN109479886A (zh) | 一种含丙硫菌唑和噻菌灵的农药以及制备方法 | |
| CN106857543B (zh) | 一种含吩乙霉素和苯并烯氟菌唑的农药组合物 | |
| CN105685032A (zh) | 一种含环酰菌胺的增效杀菌组合物 | |
| CN107318856B (zh) | 包含二氯噁菌唑和喹啉铜的杀菌组合物 | |
| CN101946793A (zh) | 一种含有氟吡菌酰胺和异菌脲的杀菌组合物 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180918 Address after: 362000 Fujian province Quanzhou Huian Taiwan investment zone Luoyang Town, Qian Yuan Village Luoyang Pioneer Park two floor. Applicant after: Quanzhou poetry exhibition culture development Co.,Ltd. Address before: 528000 2 Chancheng Zhi Bo Li Hai garden, Ji Hua three road, Chancheng District, Foshan, Guangdong Applicant before: Li Xiangying |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201210 Address after: 215600 room 145, A building, new industry incubation center, Zhangjiagang Free Trade Zone, Suzhou, Jiangsu Patentee after: SUZHOU RUNTONG PATENT OPERATION Co.,Ltd. Address before: 362000 Fujian province Quanzhou Huian Taiwan investment zone Luoyang Town, Qian Yuan Village Luoyang Pioneer Park two floor. Patentee before: Quanzhou poetry exhibition culture development Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20230512 Address after: 466000, 2.5 kilometers north of Laozhong Town, Taikang County, Zhoukou City, Henan Province (east side of National Highway 106) Patentee after: Henan Yongguan Qiaodi Agricultural Technology Co.,Ltd. Address before: 215600 room 145, A building, new industry incubation center, Zhangjiagang Free Trade Zone, Suzhou, Jiangsu Patentee before: SUZHOU RUNTONG PATENT OPERATION Co.,Ltd. |