CN105816408A - Medical stone facial mask and preparation method thereof - Google Patents
Medical stone facial mask and preparation method thereof Download PDFInfo
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- CN105816408A CN105816408A CN201610255935.3A CN201610255935A CN105816408A CN 105816408 A CN105816408 A CN 105816408A CN 201610255935 A CN201610255935 A CN 201610255935A CN 105816408 A CN105816408 A CN 105816408A
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- 230000001815 facial effect Effects 0.000 title claims abstract description 80
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 239000004575 stone Substances 0.000 title abstract 9
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 72
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 68
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 30
- 241000576855 Syringa reticulata Species 0.000 claims abstract description 24
- 150000004676 glycans Chemical class 0.000 claims abstract description 24
- 229920001282 polysaccharide Polymers 0.000 claims abstract description 24
- 239000005017 polysaccharide Substances 0.000 claims abstract description 24
- 238000004806 packaging method and process Methods 0.000 claims abstract description 6
- 241001116389 Aloe Species 0.000 claims description 22
- 241000221377 Auricularia Species 0.000 claims description 22
- 241000628997 Flos Species 0.000 claims description 22
- 102000004407 Lactalbumin Human genes 0.000 claims description 22
- 108090000942 Lactalbumin Proteins 0.000 claims description 22
- 235000011399 aloe vera Nutrition 0.000 claims description 22
- 238000000605 extraction Methods 0.000 claims description 22
- 239000008367 deionised water Substances 0.000 claims description 8
- 229910021641 deionized water Inorganic materials 0.000 claims description 8
- 238000009835 boiling Methods 0.000 claims description 5
- 238000010438 heat treatment Methods 0.000 claims description 5
- 230000001954 sterilising effect Effects 0.000 abstract description 8
- 208000002874 Acne Vulgaris Diseases 0.000 abstract description 7
- 206010000496 acne Diseases 0.000 abstract description 7
- 238000004659 sterilization and disinfection Methods 0.000 abstract description 5
- 230000008033 biological extinction Effects 0.000 abstract description 4
- 239000002537 cosmetic Substances 0.000 abstract description 3
- 239000007864 aqueous solution Substances 0.000 abstract 3
- 235000000023 Auricularia auricula Nutrition 0.000 abstract 2
- 241001149430 Auricularia auricula-judae Species 0.000 abstract 2
- 241001312894 Trollius chinensis Species 0.000 abstract 2
- 108010046377 Whey Proteins Proteins 0.000 abstract 2
- 102000007544 Whey Proteins Human genes 0.000 abstract 2
- 240000008042 Zea mays Species 0.000 abstract 2
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 abstract 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 2
- 229940069521 aloe extract Drugs 0.000 abstract 2
- 235000012907 honey Nutrition 0.000 abstract 2
- 235000009973 maize Nutrition 0.000 abstract 2
- 235000021119 whey protein Nutrition 0.000 abstract 2
- 208000028990 Skin injury Diseases 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 12
- 206010015150 Erythema Diseases 0.000 description 9
- 206010030113 Oedema Diseases 0.000 description 9
- 231100000321 erythema Toxicity 0.000 description 9
- 241000186427 Cutibacterium acnes Species 0.000 description 6
- 241000283973 Oryctolagus cuniculus Species 0.000 description 6
- 230000001154 acute effect Effects 0.000 description 6
- 210000000795 conjunctiva Anatomy 0.000 description 6
- 230000002757 inflammatory effect Effects 0.000 description 6
- 229940055019 propionibacterium acne Drugs 0.000 description 6
- 208000037816 tissue injury Diseases 0.000 description 6
- 230000000844 anti-bacterial effect Effects 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 206010061218 Inflammation Diseases 0.000 description 4
- 241000195622 Astasia Species 0.000 description 3
- 241000700199 Cavia porcellus Species 0.000 description 3
- 206010010947 Coordination abnormal Diseases 0.000 description 3
- 206010020751 Hypersensitivity Diseases 0.000 description 3
- 206010070834 Sensitisation Diseases 0.000 description 3
- 206010040880 Skin irritation Diseases 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 231100000293 acute skin toxicity Toxicity 0.000 description 3
- 208000026935 allergic disease Diseases 0.000 description 3
- 230000007815 allergy Effects 0.000 description 3
- 208000006673 asthma Diseases 0.000 description 3
- 230000006399 behavior Effects 0.000 description 3
- 210000004204 blood vessel Anatomy 0.000 description 3
- 210000005252 bulbus oculi Anatomy 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 210000004087 cornea Anatomy 0.000 description 3
- 238000011156 evaluation Methods 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- 238000000465 moulding Methods 0.000 description 3
- 230000008313 sensitization Effects 0.000 description 3
- 230000035939 shock Effects 0.000 description 3
- 206010040560 shock Diseases 0.000 description 3
- 231100000475 skin irritation Toxicity 0.000 description 3
- 230000036556 skin irritation Effects 0.000 description 3
- 206010040882 skin lesion Diseases 0.000 description 3
- 231100000444 skin lesion Toxicity 0.000 description 3
- 238000010181 skin prick test Methods 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 235000010755 mineral Nutrition 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003442 weekly effect Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 230000003255 anti-acne Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000003467 diminishing effect Effects 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 229910052761 rare earth metal Inorganic materials 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/65—Collagen; Gelatin; Keratin; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
- A61K8/988—Honey; Royal jelly, Propolis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Biotechnology (AREA)
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- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a medical stone facial mask and a preparation method thereof, relates to facial masks and preparation methods thereof, and aims to solve the technical problem that no facial mask for preventing and treating acne is not provided. The facial mask is prepared from glycerinum, propylene glycol, aloe extract, honey, auricularia auricula polysaccharide, whey protein, trollius chinensis extract, syringa reticulata extract, maize pollen and medical stone aqueous solution. The preparation method comprises the following steps: 1, preparing a medical stone aqueous solution; 2, dissolving whey protein in the medical stone water, mixing glycerinum, propylene glycol, aloe extract, honey, auricularia auricula polysaccharide, trollius chinensis extract, syringa reticulata extract, maize pollen and medical stone aqueous solution, and homogenizing with a homogenizer; and 3, soaking facial mask paper, picking up, and packaging to obtain the medical stone facial mask. Compared with commercial similar products having the similar price, the medical stone facial mask has the advantages that the sterilization rate can be improved by 12.3 percent, and the skin injury extinction rate is 24.5 percent. The medical stone facial mask belongs to the field of cosmetics.
Description
Technical field
The invention belongs to cosmetic field, molding Maifanitum facial film especially relating to a kind of anti-inflammation and preparation method thereof.
Background technology
Maifanitum is that one is harmless to biological nontoxic, has certain bioactive mineral health care YAOSHI, do not contain only the various mineral required for organism, and rich in trace element and to the useful rare earth element of human body and rare element, there is the functional attributes such as good dissolution, absorption and biological activity.It is widely used in fields such as medical treatment, health care, food, daily-use chemical industry, environmental conservation, agricultural and animal husbandry.
Inhibiting bacteria and diminishing inflammation is one of main path preventing and treating acne, and therefore exploitation product for resolving poxes can be started with from this approach.The most also there is not the facial film preventing and treating acne.
Summary of the invention
The present invention is the technical problem in order to solve not prevent and treat the facial film of acne, it is provided that a kind of Maifanitum facial film and preparation method thereof, molding Maifanitum facial film being specifically related to a kind of anti-inflammation and preparation method thereof.
It has function and the characteristics such as sterilization, antiinflammatory, anti-acne, nontoxic, no dependence, skin contact are good, provides the Chinese medicine cosmetics of a kind of new type health for broad masses of the people.
The preparation of the molding Maifanitum facial film of a kind of anti-inflammation, it is made up of face paper and Maifanitum facial film solution.
Described Maifanitum facial film solution is made up of the ratio of weight and number of following component: 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.01-0.05 part lactalbumin, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 60-90 part maifanite solution form；In described Maifanitum water, Maifanitum is 1:5 with the mass ratio of deionized water.
The preparation method of Maifanitum facial film follows the steps below:
One, Maifanitum and the deionized water ratio with mass ratio as 1:5 are mixed in boiling water bath heating, under conditions of supersonic frequency is 75 kilo hertzs～90 kilo hertzs ultrasonic 20 minutes, obtain maifanite solution；
Two, first 0.01-0.05 part lactalbumin is dissolved in 20-30 part Maifanitum water dissolving, then it is mixed employing homogenizer homogenizing 20-30 minute with 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 40-60 weight portion maifanite solution, i.e. obtain Maifanitum facial film solution；
Three, face paper is immersed in Maifanitum facial film solution, pulls out, packaging, obtain Maifanitum facial film.
Maifanitum surface irregularity, porous is spongy, and wherein contains a large amount of silicone atom group, can with protein bound in each antibacterial and adsorb antibacterial, therefore have absorption cleaning effect.
Antibacterial and the sterilizing ability carrying out Maifanitum facial film that propionibacterium acnes inhibition test finds prepared by this experiment propionibacterium acnes to causing acne is relatively strong, and compared with equal price like product on the market, sterilization ratio can improve 12.3%；The skin being grievously injured degree evaluation finds that skin surface has the experimental rat of erythema, and skin lesion extinction rate is 24.5%.
After acute dermal toxicity test finds percutaneous primary coating Maifanitum facial film, rat does not occurs Health cost effect in a short time.Rat performance without exception (behavior and clinical characteristics are without exception)；What after acute skin irritation experimental rabbits cutaneous application facial film, local produced changes and tissue injury without inflammatory, without erythema, edema；Without inflammatory change and tissue injury after acute ocular irritation test rabbit eyeball surface contact facial film.Cornea without ulcer or muddiness, iris is normal, refer to palpebral conjunctiva and bulbar conjunctiva position blood vessel is normal, without edema；Skin allergy test test guinea pig skin is without erythema and edema, and sensitization rate 0.003% is in tolerance interval, without severe allergy phenomenons such as asthma, astasia or shocks.
Detailed description of the invention
Technical solution of the present invention is not limited to act detailed description of the invention set forth below, also includes the combination in any between each detailed description of the invention.
Detailed description of the invention one: present embodiment Maifanitum facial film is made up of 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.01-0.05 part lactalbumin, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 60-90 part maifanite solution according to parts by weight；In described Maifanitum water, Maifanitum is 1:5 with the mass ratio of deionized water.
Every bag of finished product facial film of the Maifanitum facial film of present embodiment weighs about 20g, and consumption is 2-3 time weekly.
Detailed description of the invention two: present embodiment Maifanitum facial film unlike detailed description of the invention one is made up of 26 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.005 Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 68.96 parts of maifanite solutions according to parts by weight.Other is identical with detailed description of the invention one.
Detailed description of the invention three: present embodiment Maifanitum facial film unlike one of detailed description of the invention one or two is made up of 24 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.01 Auricularia polysaccharide, 0.01 part of Flos Trollii extract, 0.01 part of syringa reticulata var mandshurica extract, 0.01 part of Pollen Maydis and 70.94 parts of maifanite solutions according to parts by weight.Other is identical with one of detailed description of the invention one or two.
Detailed description of the invention four: present embodiment Maifanitum facial film unlike one of detailed description of the invention one to three is made up of 28 parts of glycerol, 2 parts of propylene glycol, 1 part of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 67.96 parts of maifanite solutions according to parts by weight.Other is identical with one of detailed description of the invention one to three.
Detailed description of the invention five: described in detailed description of the invention one, the preparation method of Maifanitum facial film follows the steps below:
One, Maifanitum and the deionized water ratio with mass ratio as 1:5 are mixed in boiling water bath heating, under conditions of supersonic frequency is 75 kilo hertzs～90 kilo hertzs ultrasonic 20 minutes, obtain maifanite solution；
Two, first 0.01-0.05 part lactalbumin is dissolved in 20-30 part Maifanitum water dissolving, then it is mixed employing homogenizer homogenizing 20-30 minute with 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 40-60 weight portion maifanite solution, i.e. obtain Maifanitum facial film solution；
Three, face paper is immersed in Maifanitum facial film solution, pulls out, packaging, obtain Maifanitum facial film.Every bag of finished product facial film of the Maifanitum facial film of present embodiment weighs about 20g, and consumption is 2-3 time weekly.
Detailed description of the invention six: in present embodiment step one unlike detailed description of the invention five under conditions of supersonic frequency is 80 kilo hertzs ultrasonic 20 minutes.Other is identical with detailed description of the invention five.
Detailed description of the invention seven: first 0.02 part of lactalbumin is dissolved in 20 parts of Maifanitum water in present embodiment step 2 unlike detailed description of the invention five or six dissolving, then it is mixed employing homogenizer homogenizing 20 minutes with 26 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 48.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution；Other is identical with detailed description of the invention five or six.
Detailed description of the invention eight: first 0.02 part of lactalbumin is dissolved in 25 parts of Maifanitum water in present embodiment step 2 unlike one of detailed description of the invention five to seven dissolving, then it is mixed employing homogenizer homogenizing 25 minutes with 24 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.01 part of Auricularia polysaccharide, 0.01 part of Flos Trollii extract, 0.01 part of syringa reticulata var mandshurica extract, 0.01 part of Pollen Maydis and 45.94 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution；Other is identical with one of detailed description of the invention five to seven.
Detailed description of the invention nine: first 0.02 part of lactalbumin is dissolved in 30 parts of Maifanitum water in present embodiment step 2 unlike one of detailed description of the invention five to eight dissolving, then it is mixed employing homogenizer homogenizing 28 minutes with 28 parts of glycerol, 2 parts of propylene glycol, 1 part of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 37.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.Other is identical with one of detailed description of the invention five to eight.
Detailed description of the invention ten: first 0.02 part of lactalbumin is dissolved in 25 parts of Maifanitum water in present embodiment step 2 unlike one of detailed description of the invention five to nine dissolving, then it is mixed employing homogenizer homogenizing 30 minutes with 24 parts of glycerol, 1 part of propylene glycol, 3 parts of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 45.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.Other is identical with one of detailed description of the invention five to nine.
Use following experimental verification effect of the present invention:
Experiment one:
The preparation method of Maifanitum facial film follows the steps below:
One, Maifanitum and the deionized water ratio with mass ratio as 1:5 are mixed in boiling water bath heating, under conditions of supersonic frequency is 80 kilo hertzs ultrasonic 20 minutes, obtain maifanite solution；
Two, first 0.02g lactalbumin is dissolved in 20g Maifanitum water dissolving, then it is mixed employing homogenizer homogenizing 30 minutes with 26g glycerol, 2g propylene glycol, 2g Aloe extraction solution, 1g Mel, 0.005g Auricularia polysaccharide, 0.005g Flos Trollii extract, 0.005g syringa reticulata var mandshurica extract, 0.005g Pollen Maydis and 48.96g maifanite solution, i.e. obtain Maifanitum facial film solution；
Three, face paper is immersed in Maifanitum facial film solution, pulls out, packaging, obtain Maifanitum facial film.
Antibacterial and the sterilizing ability carrying out Maifanitum facial film that propionibacterium acnes inhibition test finds prepared by this experiment propionibacterium acnes to causing acne is relatively strong, and compared with equal price like product on the market, sterilization ratio improves 12.3%；The skin being grievously injured degree evaluation finds that skin surface has the experimental rat of erythema, and skin lesion extinction rate is 24.5%.
After acute dermal toxicity test finds percutaneous primary coating Maifanitum facial film, rat does not occurs Health cost effect in a short time.Rat performance without exception (behavior and clinical characteristics are without exception)；What after acute skin irritation experimental rabbits cutaneous application facial film, local produced changes and tissue injury without inflammatory, without erythema, edema；Without inflammatory change and tissue injury after acute ocular irritation test rabbit eyeball surface contact facial film.Cornea without ulcer or muddiness, iris is normal, refer to palpebral conjunctiva and bulbar conjunctiva position blood vessel is normal, without edema；Skin allergy test test guinea pig skin is without erythema and edema, and sensitization rate 0.003% is in tolerance interval, without severe allergy phenomenons such as asthma, astasia or shocks.
Experiment two:
The preparation method of Maifanitum facial film follows the steps below:
One, Maifanitum and the deionized water ratio with mass ratio as 1:5 are mixed in boiling water bath heating, under conditions of supersonic frequency is 80 kilo hertzs ultrasonic 20 minutes, obtain maifanite solution；
Two, first 0.02 part of lactalbumin is dissolved in 30 parts of Maifanitum water dissolving, then it is mixed employing homogenizer homogenizing 28 minutes with 28 parts of glycerol, 2 parts of propylene glycol, 1 part of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 37.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution；
Three, face paper is immersed in Maifanitum facial film solution, pulls out, packaging, obtain Maifanitum facial film.
Antibacterial and the sterilizing ability carrying out Maifanitum facial film that propionibacterium acnes inhibition test finds prepared by this experiment propionibacterium acnes to causing acne is relatively strong, and compared with equal price like product on the market, sterilization ratio improves 12.2%；The skin being grievously injured degree evaluation finds that skin surface has the experimental rat of erythema, and skin lesion extinction rate is 24.3%.
After acute dermal toxicity test finds percutaneous primary coating Maifanitum facial film, rat does not occurs Health cost effect in a short time.Rat performance without exception (behavior and clinical characteristics are without exception)；What after acute skin irritation experimental rabbits cutaneous application facial film, local produced changes and tissue injury without inflammatory, without erythema, edema；Without inflammatory change and tissue injury after acute ocular irritation test rabbit eyeball surface contact facial film.Cornea without ulcer or muddiness, iris is normal, refer to palpebral conjunctiva and bulbar conjunctiva position blood vessel is normal, without edema；Skin allergy test test guinea pig skin is without erythema and edema, and sensitization rate 0.003% is in tolerance interval, without severe allergy phenomenons such as asthma, astasia or shocks.
Claims (10)
1. Maifanitum facial film, it is characterised in that Maifanitum facial film is made up of 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.01-0.05 part lactalbumin, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 60-90 part maifanite solution according to parts by weight；In described Maifanitum water, Maifanitum is 1:5 with the mass ratio of deionized water.
Maifanitum facial film the most according to claim 1, it is characterised in that Maifanitum facial film is made up of 26 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.005 Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 68.96 parts of maifanite solutions according to parts by weight.
Maifanitum facial film the most according to claim 1, it is characterised in that Maifanitum facial film is made up of 24 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.01 Auricularia polysaccharide, 0.01 part of Flos Trollii extract, 0.01 part of syringa reticulata var mandshurica extract, 0.01 part of Pollen Maydis and 70.94 parts of maifanite solutions according to parts by weight.
Maifanitum facial film the most according to claim 1, it is characterised in that Maifanitum facial film is made up of 28 parts of glycerol, 2 parts of propylene glycol, 1 part of Aloe extraction solution, 1 part of Mel, 0.02 part of lactalbumin, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 67.96 parts of maifanite solutions according to parts by weight.
5. the preparation method of Maifanitum facial film described in claim 1, it is characterised in that the preparation method of Maifanitum facial film follows the steps below:
One, Maifanitum and the deionized water ratio with mass ratio as 1:5 are mixed in boiling water bath heating, under conditions of supersonic frequency is 75 kilo hertzs～90 kilo hertzs ultrasonic 20 minutes, obtain maifanite solution；
Two, first 0.01-0.05 part lactalbumin is dissolved in 20-30 part Maifanitum water dissolving, then it is mixed employing homogenizer homogenizing 20-30 minute with 24-28 part glycerol, 1-4 part propylene glycol, 1-4 part Aloe extraction solution, 0.5-3 part Mel, 0.001-0.1 part Auricularia polysaccharide, 0.001-0.1 part Flos Trollii extract, 0.001-0.05 part syringa reticulata var mandshurica extract, 0.001-0.5 part Pollen Maydis and 40-60 weight portion maifanite solution, i.e. obtain Maifanitum facial film solution；
Three, face paper is immersed in Maifanitum facial film solution, pulls out, packaging, obtain Maifanitum facial film.
The preparation method of Maifanitum facial film the most according to claim 5, it is characterised in that in step one under conditions of supersonic frequency is 80 kilo hertzs ultrasonic 20 minutes.
The preparation method of Maifanitum facial film the most according to claim 5, it is characterized in that first 0.02 part of lactalbumin is dissolved in 20 parts of Maifanitum water by step 2 dissolving, then it is mixed employing homogenizer homogenizing 20 minutes with 26 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 48.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.
The preparation method of Maifanitum facial film the most according to claim 5, it is characterized in that first 0.02 part of lactalbumin is dissolved in 25 parts of Maifanitum water by step 2 dissolving, then it is mixed employing homogenizer homogenizing 25 minutes with 24 parts of glycerol, 2 parts of propylene glycol, 2 parts of Aloe extraction solution, 1 part of Mel, 0.01 part of Auricularia polysaccharide, 0.01 part of Flos Trollii extract, 0.01 part of syringa reticulata var mandshurica extract, 0.01 part of Pollen Maydis and 45.94 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.
The preparation method of Maifanitum facial film the most according to claim 5, it is characterized in that first 0.02 part of lactalbumin is dissolved in 30 parts of Maifanitum water by step 2 dissolving, then it is mixed employing homogenizer homogenizing 28 minutes with 28 parts of glycerol, 2 parts of propylene glycol, 1 part of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 37.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.
The preparation method of Maifanitum facial film the most according to claim 5, it is characterized in that first 0.02 part of lactalbumin is dissolved in 25 parts of Maifanitum water by step 2 dissolving, then it is mixed employing homogenizer homogenizing 30 minutes with 24 parts of glycerol, 1 part of propylene glycol, 3 parts of Aloe extraction solution, 1 part of Mel, 0.005 part of Auricularia polysaccharide, 0.005 part of Flos Trollii extract, 0.005 part of syringa reticulata var mandshurica extract, 0.005 part of Pollen Maydis and 45.96 weight portion maifanite solutions, i.e. obtain Maifanitum facial film solution.
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Application publication date: 20160803 |