CN105343450A - Emulsion for treating keratosis pilaris and preparation method of emulsion - Google Patents

Abstract

The invention discloses an emulsion for treating keratosis pilaris and a preparation method thereof. The emulsion contains the following substances: aloe vera oil, avocado oil, chamomile, acacia gum, tragacanth gum, sodium alginate, and centella asiatica Extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, tretinoin, vitamin A, urea, salicylic acid, glycerin, ethylparaben alcohol solution, distilled water. Most of the raw materials in this product are extracted from traditional Chinese medicinal materials. It adopts the method of combining natural component extracts and plant essential oils. It has the characteristics of mild nature and high safety. It is less irritating to the skin, non-toxic, and has no side effects. Suitable for people with sensitive skin types. Various traditional Chinese medicines are used together to give full play to their synergistic compatibility, which can effectively improve the symptoms of keratosis follicles. It also has the effect of moisturizing, nourishing and easy to absorb, making the skin firm, supple and elastic.

Description

A kind of emulsion for treating keratosis pilaris and preparation method thereof

technical field

The invention relates to an emulsion, in particular to an emulsion for treating keratosis pilaris and a preparation method thereof, belonging to the field of cosmetic pharmacy.

Background technique

Keratosis pilaris, keratosis pilaris, commonly known as chicken skin, is a hereditary skin disease with abnormal keratinization process caused by autosomal dominant inheritance. Some people think that vitamin A metabolism disorder and sunlight exposure are important pathogenic factors. For people with this constitution, the cutin around the hair follicles will thicken, causing the opening of the hair follicles to be blocked by the thick cutin, forming small bumps. It is manifested as dry skin, pimples, roughness, and fine hairs curled up in the hair follicles, which greatly affects the appearance.

Keratosis pilaris makes people want to get rid of it quickly, but squeezing, grabbing, and picking with hands will make the tissue around the pores edema, so that the opening of the pores becomes smaller and more likely to be blocked, resulting in acne and folliculitis; if Scratching can cause inflammation and pigmentation. So don't scratch or scratch. This will not only easily hurt the skin, but also easily irritate the skin and inflame the hair follicles, causing scars and pigmentation. Applying retinoic acid, or performing a fruit acid peel under the guidance of a professional physician, can improve the skin within a few days. But this is only an "emergency method", and it will treat the symptoms but not the root cause. If you often deal with it like this, it will also make the skin's barrier function weaker, making the skin drier and more sensitive.

According to Chinese medical theory, keratosis pilaris is mostly caused by damp heat accumulating inside, and externally receiving heat evil, which then fumigates the lung system and accumulates in the skin. Evil poison stagnates for a long time and turns into heat, and the meat rots with heat and becomes pus. Or it may be caused by weak body, weak defense, exogenous pathogenic heat and poison; or due to unclean skin, it is attacked by wind poison again, and the wind causes external stroke. According to the pathology of keratosis pilaris, congenital deficiencies, blood deficiency and wind-dryness, resulting in hair loss due to the disharmony of the skin and defense, the disease is treated with traditional Chinese medicines that have the effects of moisturizing the skin, activating collaterals, dispelling blood stasis, dispelling wind and relieving itching, and the curative effect is very significant , so now many patients will take traditional Chinese medicine and traditional Chinese medicine to treat keratosis pilaris.

Studies have found that lack of vitamin A will cause general dryness, and dryness will aggravate the symptoms of keratosis of hair follicles. Salicylic acid itself is fat-soluble, and it can just follow the hair follicle opening, follow the skin oil to reach the keratinized part, and then dissolve the keratin and improve the symptoms. Urea and vitamin A acid can soften cutin and moisturize skin. Raw materials such as centella asiatica, licorice, angelica, natural chamomile, and loofah are effective and safe ingredients for treating folliculitis, which can reduce skin irritation, antibacterial and anti-inflammatory, clear heat and relieve itching, enhance human immunity, and reduce allergic reactions. It can improve hypersensitive skin such as moss eczema, and at the same time purify the skin. It can also effectively and safely improve or even eliminate folliculitis. If the corresponding functional ingredients are added to the lotion, it can moisturize and nourish the skin while relieving and dissolving cutin, so that the skin can be fully moisturized, and the problem of keratosis pilaris can be gradually improved.

Contents of the invention

In order to solve the problems in the prior art, the invention provides an emulsion for treating keratosis pilaris, which can effectively improve and treat keratosis pilaris by adopting a scientific preparation method.

In order to achieve the above object, the technical scheme that the present invention takes is:

An emulsion for the treatment of keratosis pilaris, comprising the following substances:

The aloe vera oil, avocado oil, gum arabic, gum tragacanth, sodium alginate, tretinoin, vitamin A, urea, salicylic acid, and glycerin are commercially available.

The 2% ethylparaben alcohol solution is prepared by 2% volume ratio of ethylparaben and 75% (volume ratio) ethanol solution.

A preparation method for an emulsion for the treatment of keratosis pilaris, comprising the following steps:

Step 1: Weigh salicylic acid, dissolve it in 1-10ml distilled water, and use it as solution 1 for later use;

Step 2: Weigh tretinoin, vitamin A, and urea, dissolve them in 5-15ml of distilled water, and use them as solution 2 for later use;

Step 3: Weigh sodium alginate, disperse it in 30-60ml distilled water, stir and dissolve it, and use it as gel solution 3 for later use;

Step 4: Take aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 2-10ml of distilled water, and grind them evenly to get Colostrum 1;

Step 5: Add solution 1, solution 2, gel solution 3 and 2-10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1;

Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris.

Described chamomile steeping oil is prepared by the following method:

Weigh 20-40g of natural chamomile, soak it in olive oil 6-15 times the weight of chamomile for 1-5 days, put it into an ultrasonic extractor, heat it to 30-60°C, and extract it by ultrasonic for 0.5-1.5h, with a power of 240W. The frequency is 40kHz, and the chamomile soaked oil is obtained by filtering with double-layer gauze.

Described licorice extract is prepared by the following method:

Weigh 30-50g of licorice, crush it into coarse powder, add 10-15 times the weight of licorice, soak in water for 0.25-0.80h, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; Add water 8-10 times the weight of the filter residue, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 2; then add water 6-8 times the weight of the filter residue to the filter residue, heat to 90-100°C , decocted and extracted for 0.5-1.5h, filtered to obtain filtrate 3; combined filtrate 1, filtrate 2, and filtrate 3, and concentrated to 5-8 times the weight of licorice at a temperature of 80-100°C to obtain licorice extract.

The described centella asiatica extract is prepared by the following method:

Weigh 20-50g Centella asiatica, add 15-20 times the weight of Centella asiatica, soak in water for 0.25-0.80h, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; add to the filter residue 10-15 times the weight of the filter residue, heated to 90-100°C, decocted and extracted for 0.5-1.5h, and filtered to obtain the filtrate 2; then add 10-12 times the weight of the filter residue to the water, heated to 90-100°C, Decoct and extract for 0.5-1.5 hours, filter to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate to 5-8 times the weight of Centella asiatica at a temperature of 80-100°C to obtain Centella asiatica extract.

Described luffa extract is prepared by the following method:

Weigh 100-200g of fresh loofah, cut into slices, add water 10-15 times the weight of loofah, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; add 10-15 Water twice the weight of the filter residue, heated to 90-100°C, decocted and extracted for 0.5-1.5h, filtered to obtain filtrate 2; then add water 10-12 times the weight of the filter residue to the filter residue, heated to 90-100°C, decocted and extracted 0.5-1.5h, filtrate to get filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate at a temperature of 80-100°C to 5-8 times the weight of the loofah to obtain the loofah extract.

Described angelica extract is prepared by the following method:

Weigh 40-50g of Angelica sinensis, crush it into coarse powder, add 75% (volume ratio) ethanol solution 10-16 times the weight of Angelica sinensis, soak for 0.25-0.80h, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain the filtrate 1 Add 10-15 times the weight of 75% ethanol solution to the filter residue, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 2; add 8-10 times the weight of 75% ethanol solution to the filter residue, Reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate under reduced pressure at a temperature of 40-50°C and a vacuum of 0.05-0.08Pa to the weight of Angelica sinensis 5-8 times of that, the Angelica sinensis extract is obtained.

The described Cortex Moutan extract is prepared by the following method:

Weigh 30-50g of Moutan Cortex, crush it into coarse powder, add 70% (volume ratio) ethanol solution 10-16 times the weight of Moutan Cortex, soak for 0.25-0.80h, reflux extraction for 0.5-1.5h, and filter with 3 layers of gauze to obtain Filtrate 1; add 70% ethanol solution 10-15 times the weight of the filter residue to the filter residue, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 2; then add 70% ethanol 8-10 times the weight of the filter residue to the filter residue Solution, reflux extraction for 0.5-1.5h, filtered with 3 layers of gauze to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate under reduced pressure at a temperature of 40-50°C and a vacuum of 0.05-0.08Pa to 5-8 times the weight of Moutan Cortex to obtain Moutan Cortex extract.

Aloe vera oil contains natural gelatinous substances, water-retaining lignin, and has strong penetrating substances, which can help nutrients penetrate into skin saponins. It not only has powerful cleaning and antibacterial effects, but also has direct beauty effects such as moisturizing, whitening and freckle removal, anti-aging, and anti-allergic. The β-carotene contained in aloe vera oil can improve the detoxification function of the body, facilitate the rapid inactivation of carcinogens, and inhibit the activation of carcinogen precursors. It can also eliminate free radicals and prevent the generation of free radicals. Delay skin aging. Aloe vera oil is suitable for all skin types, especially for oily skin and skin prone to inflammation. The pure oily aloe vera gel contained in it can give deeper moisture and nutrients to burns, abrasions and skin that loses moisture after sun exposure, and quickly repair damaged cell tissues, promote cell regeneration, and make your skin The skin is restored to health.

Avocado oil is rich in vitamin B2. It has good permeability and can penetrate into the epidermis of the skin. It has a very good moisturizing effect on dry skin, gives the skin sufficient moisture, and makes the skin fair, delicate and shiny. Suitable for dry, aging and problem skin.

Chamomile soaking oil has the effects of anti-aging, moisturizing, moisturizing, soothing, calming the skin and constricting pores; plus it has the effect of cooling and helping skin tissue regeneration, and can also play a very good role in relaxing and soothing the skin, which can help improve Dry skin, eczema and other hypersensitive skin can purify the skin while treating folliculitis.

Centella asiatica extract can tighten the connection between epidermis and dermis, make the skin soft, promote the regeneration of skin collagen, enhance the vitality of cells in the basal layer, and keep the skin elastic and firm, thus helping to solve the phenomenon of skin relaxation and make the skin Smooth and elastic. While promoting the close connection between the epidermis and the dermis, it can also inhibit the increase of fat cells and prevent skin edema and obesity. It has antioxidant effect, can inhibit free radical activity, regulate skin immunity, dilute melanin, increase skin water retention, activate and renew skin cells.

Licorice extract contains iridium glycyrrhizinate - glycyrrhizic acid and glycyrrhetinate, which has anti-inflammatory and anti-allergic effects, and can also inhibit capillary permeability. Licorice has mineralocorticosteroid-like and glucocorticoid-like effects. Licorice flavonoids can also inhibit tyrosinase activity and scavenge oxygen radicals, and its antioxidant capacity is closer to that of vitamin E.

The loofah extract contains sugar, plant mucus, vitamins and minerals, etc., which can maintain the normal water content of the cuticle, slow down dehydration and prolong the hydration; it can also promote metabolism, gently absorb old waste cutin, remove deep dirt, and inhibit melanin Cell generation can effectively improve rough and wrinkled skin, making the skin soft and shiny. In addition, the loofah extract also has the functions of promoting blood circulation and dredging collaterals, clearing away heat and moisturizing skin. Regular use can effectively remove blackheads and acne on the facial skin. Loofah juice is sweet and mild in nature, can regulate facial sebum secretion, and has refreshing, astringent, calming and balancing functions on facial skin.

Moutan bark extract has anti-inflammatory and antibacterial effects, can effectively resist inflammation and kill bacteria. It can increase the body's immunity, provide the body's immune system defense, and prevent the body from being infected by viruses to a certain extent.

Angelica extract can expand peripheral blood vessels, reduce vascular resistance, increase circulating blood volume, etc. Tyrosinase in the human body can produce melanin that causes freckles, dark spots, and age spots. The higher the activity, the earlier the appearance of age spots and the greater the number. The aqueous solution of angelica has a strong function of inhibiting the activity of tyrosinase, so it can inhibit the formation of melanin, and has good effect on the treatment of pigmented skin diseases such as chloasma and freckles, and has anti-aging and cosmetic effects. Add angelica to beauty cream and freckle cream to nourish the skin, prevent rough skin, and prevent acne, chloasma, and freckles.

Glycerin is a humectant and a penetration enhancer, which can effectively promote the transdermal absorption of the functional ingredients in the prescription.

The beneficial effect of the present invention is that: most of the raw materials in this product are extracted from Chinese medicinal materials, and the method of combining natural component extracts with plant essential oils is adopted, which has the characteristics of mild nature and high safety, and is less irritating to the skin , non-toxic, no side effects, suitable for all kinds of people with sensitive skin. Various traditional Chinese medicines are used together to give full play to their synergistic compatibility, which can effectively improve the symptoms of keratosis follicles. It also has the effect of moisturizing, nourishing and easy to absorb, making the skin firm, supple and elastic.

detailed description

Example 1

An emulsion for treating keratosis pilaris, comprising the following substances: 2ml of aloe vera oil, 1ml of avocado oil, 2ml of chamomile soaking oil, 1.5g of gum arabic, 0.5g of gum tragacanth, 0.4g of sodium alginate, and centella asiatica 2ml of extract, 2ml of licorice extract, 2ml of loofah extract, 2ml of Moutan bark extract, 2ml of angelica extract, 0.09g of tretinoin, 0.1g of vitamin A, 0.5g of urea, 0.6g of salicylic acid, 4ml of glycerin, 2 % ethylparaben alcohol solution 1ml, distilled water 81ml.

A preparation method for an emulsion for the treatment of keratosis pilaris, comprising the following steps:

Step 1: Weigh salicylic acid, dissolve it in 3ml distilled water, and use it as solution 1, set aside;

Step 2: Weigh retinoic acid, vitamin A, and urea, dissolve them in 10ml of distilled water, and use them as solution 2 for later use;

Step 3: Weigh sodium alginate, disperse it in 50ml of distilled water, stir to dissolve, and use it as gel solution 3 for later use;

Step 4: Measure aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 8ml of distilled water, and grind them evenly to obtain colostrum 1;

Step 5: Add solution 1, solution 2, gel solution 3 and 10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1;

Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris.

Example 2

An emulsion for treating keratosis pilaris, comprising the following substances: 2ml of aloe vera oil, 2ml of avocado oil, 2ml of chamomile soaking oil, 2g of gum arabic, 1g of tragacanth gum, 0.3g of sodium alginate, and centella asiatica extract 2ml, licorice extract 3ml, loofah extract 3ml, moutan bark extract 2ml, angelica extract 2ml, retinoic acid 0.05g, vitamin A 0.1g, urea 0.5g, salicylic acid 0.5g, glycerin 4ml, 2% nitric acid Parkin ethyl alcohol solution 1ml, distilled water 66ml.

A preparation method for an emulsion for the treatment of keratosis pilaris, comprising the following steps:

Step 1: Weigh salicylic acid, dissolve it in 3ml distilled water, and use it as solution 1, set aside;

Step 2: Weigh retinoic acid, vitamin A, and urea, dissolve them in 5ml of distilled water, and use them as solution 2 for later use;

Step 3: Weigh sodium alginate, disperse it in 40ml of distilled water, stir to dissolve, and use it as gel solution 3 for later use;

Step 4: Measure aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 8ml of distilled water, and grind them evenly to obtain colostrum 1;

Step 5: Add solution 1, solution 2, gel solution 3 and 10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1;

Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris.

Example 3

An emulsion for treating keratosis pilaris, comprising the following substances: 2ml of aloe vera oil, 2ml of avocado oil, 2ml of chamomile soaking oil, 2g of gum arabic, 1g of tragacanth gum, 0.5g of sodium alginate, and centella asiatica extract 2ml, licorice extract 2ml, loofah extract 2ml, moutan bark extract 2ml, angelica extract 2ml, retinoic acid 0.1g, vitamin A 0.1g, urea 0.5g, salicylic acid 0.7g, glycerin 4ml, 2% nitric acid Parkin ethyl alcohol solution 1ml, distilled water 81ml.

A preparation method for an emulsion for the treatment of keratosis pilaris, comprising the following steps:

Step 1: Weigh salicylic acid, dissolve it in 3ml distilled water, and use it as solution 1, set aside;

Step 2: Weigh retinoic acid, vitamin A, and urea, dissolve them in 10ml of distilled water, and use them as solution 2 for later use;

Step 3: Weigh sodium alginate, disperse it in 50ml of distilled water, stir to dissolve, and use it as gel solution 3 for later use;

Step 4: Measure aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 8ml of distilled water, and grind them evenly to obtain colostrum 1;

Step 5: Add solution 1, solution 2, gel solution 3 and 10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1;

Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris.

Example 4

An emulsion for treating keratosis pilaris, comprising the following substances: 5ml of aloe vera oil, 5ml of avocado oil, 5ml of chamomile soaking oil, 2g of gum arabic, 1g of tragacanth gum, 0.5g of sodium alginate, and centella asiatica extract 5ml, licorice extract 5ml, loofah extract 5ml, moutan bark extract 5ml, angelica extract 5ml, retinoic acid 0.15g, vitamin A 0.15g, urea 1.0g, salicylic acid 1.0g, glycerin 7ml, 2% nitric acid Parkin ethyl alcohol solution 2ml, distilled water 105ml.

A preparation method for an emulsion for the treatment of keratosis pilaris, comprising the following steps:

Step 1: Weigh salicylic acid, dissolve it in 10ml distilled water, and use it as solution 1, set aside;

Step 2: Weigh retinoic acid, vitamin A, and urea, dissolve them in 15ml of distilled water, and use them as solution 2 for later use;

Step 3: Weigh sodium alginate, disperse it in 60ml of distilled water, stir to dissolve, and use it as gel solution 3 for later use;

Step 4: Measure aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 10ml of distilled water, and grind them evenly to obtain colostrum 1;

Step 5: Add solution 1, solution 2, gel solution 3 and 10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1;

Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris.

The physicochemical index of embodiment 1,2,3,4 is as follows:

1. Texture composition test

The emulsions prepared in Examples 1, 2, 3, and 4 were squeezed onto the palm of the hand, and it was observed that the emulsion texture was soft and smooth, and the emulsion components were many and delicate.

2. pH check

Dip a small amount of emulsions prepared in Examples 1, 2, 3, and 4 with pH test paper, and the measured pH is 6-7.

3. Hot and cold test

The emulsions prepared in Examples 1, 2, 3, and 4 were packaged in transparent cosmetic bottles, and refrigerated in a refrigerator at 4° C. for one week to observe that there was no delamination. Stored in a constant temperature box at 55°C for 24 hours, the emulsion has no delamination and odor.

4. Centrifugal test

The emulsions prepared in Examples 1, 2, 3, and 4 were encapsulated in stoppered test tubes, and centrifuged at 3000r/min for 20min without delamination.

5. Irritation test, allergy test

The back hair of the mice was cut off, and the emulsions prepared in Examples 1, 2, 3, and 4 were applied to the hair-cut parts respectively. After 30 minutes, compared with the uncoated parts, the results showed no irritation and allergic reactions.

Choose 65 volunteers aged 15-65, get 1 gram of the emulsion prepared in Examples 1, 2, 3, and 4 and apply it on the hands of the volunteers, observe after 30 minutes, and there is no redness, rash, and foaming Phenomenon.

6. Placement experiment at room temperature

The emulsions prepared in Examples 1, 2, 3, and 4 were placed in a cosmetic bottle, and left standing at room temperature for 6 months, no delamination phenomenon, no change in feeling after use, and no change in smell.

7. Experiment on improving hair follicle keratinization effect

Select 200 volunteers with keratosis pilaris in the age group of 15-65 as the trial subjects, divide them into four groups arbitrarily, apply the emulsions prepared in Examples 1, 2, 3, and 4, and apply them on the For keratinized hair follicles, use it continuously for one month. Wherein embodiment 1, 50 examples, male 20 examples, female 30 examples. Embodiment 2, in 50 cases, 26 cases are male, 24 cases are female. Embodiment 3, among 50 examples, 25 examples are male, 25 examples are female. Embodiment 4, in 50 cases, 23 cases are male, 27 cases are female.

Effect standard: markedly effective: chicken skin symptoms disappear, hair follicle keratosis is significantly improved; effective: hair follicle keratosis is improved; invalid: no change. The results are shown in Table 1:

Table 1 Investigation of the effect of improving hair follicle keratinization

Effect Significant effect/person Effective/person invalid/person Efficient/% Example 1 39 5 6 88 Example 2 41 6 3 94 Example 3 40 5 5 90 Example 4 42 5 3 94

8. Comprehensive effect inspection

The efficacy of the emulsion for treating keratosis pilaris produced by the embodiment is evaluated by using the trial feeling below. Adopt the public opinion survey scoring method, select 200 people with keratosis pilaris in the age group of 15-65 as trial objects, divide them into four groups arbitrarily, and apply the emulsion prepared in the embodiment to the keratosis pilaris respectively, twice a day , used continuously for one month. The total score of each use effect is 10 points: 10 points is the highest score, which means good and very satisfied; 8 points is very good; 5 points are acceptable; below 5 points are bad and unacceptable. The following are the average scores for each item, and the results are shown in Table 2:

Table 2 Comprehensive effect investigation

Claims (10)

1. an emulsion for the treatment of keratosis pilaris, is characterized in that, comprises following material: 2. a kind of emulsion for the treatment of keratosis pilaris according to claim 1, is characterized in that, contains following material: aloe vera oil 2ml, avocado oil 1ml, chamomile soaking oil 2ml, gum arabic 1.5g, tragacanth Glue 0.5g, sodium alginate 0.4g, centella asiatica extract 2ml, licorice extract 2ml, loofah extract 2ml, moutan bark extract 2ml, angelica extract 2ml, tretinoin 0.09g, vitamin A0.1g, urea 0.5g, 0.6g salicylic acid, 4ml glycerin, 1ml 2% ethylparaben alcohol solution, 81ml distilled water. 3. a kind of emulsion for the treatment of keratosis pilaris according to claim 1, is characterized in that, contains following material: aloe vera oil 5ml, avocado oil 5ml, chamomile soaking oil 5ml, gum arabic 2g, gum tragacanth 1g, sodium alginate 0.5g, centella asiatica extract 5ml, licorice extract 5ml, loofah extract 5ml, moutan bark extract 5ml, angelica extract 5ml, tretinoin 0.15g, vitamin A 0.15g, urea 1.0g , salicylic acid 1.0g, glycerin 7ml, 2% ethylparaben alcohol solution 2ml, distilled water 105ml. 4. A preparation method for the emulsion for the treatment of keratosis pilaris according to any one of claims 1-3, characterized in that, comprising the following steps: Step 1: Weigh salicylic acid, dissolve it in 1-10ml distilled water, and use it as solution 1 for later use; Step 2: Weigh tretinoin, vitamin A, and urea, dissolve them in 5-15ml of distilled water, and use them as solution 2 for later use; Step 3: Weigh sodium alginate, disperse it in 30-60ml distilled water, stir and dissolve it, and use it as gel solution 3 for later use; Step 4: Take aloe vera oil, avocado oil, and chamomile soaked oil, put them in a mortar, weigh Arabic gum, tragacanth gum, put them in a mortar, add 2-10ml of distilled water, and grind them evenly to get Colostrum 1; Step 5: Add solution 1, solution 2, gel solution 3 and 2-10ml of distilled water to colostrum 1 in step 4, and grind evenly to obtain matrix 1; Step 6: Add Centella asiatica extract, licorice extract, loofah extract, Moutan bark extract, angelica extract, glycerin, and 2% ethylparaben alcohol solution to step 5 matrix 1, and mix well Mix evenly with a high-speed tissue grinder to obtain the emulsion for treating keratosis pilaris. 5. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described chamomile soaking oil is prepared by following method: Weigh 20-40g of natural chamomile, soak it in olive oil 6-15 times the weight of chamomile for 1-5 days, put it into an ultrasonic extractor, heat it to 30-60°C, and extract it by ultrasonic for 0.5-1.5h, with a power of 240W. The frequency is 40kHz, and the chamomile soaked oil is obtained by filtering with double-layer gauze. 6. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described licorice extract is prepared by the following method: Weigh 30-50g of licorice, crush it into coarse powder, add 10-15 times the weight of licorice, soak in water for 0.25-0.80h, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; Add water 8-10 times the weight of the filter residue, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 2; then add water 6-8 times the weight of the filter residue to the filter residue, heat to 90-100°C , decocted and extracted for 0.5-1.5h, filtered to obtain filtrate 3; combined filtrate 1, filtrate 2, and filtrate 3, and concentrated to 5-8 times the weight of licorice at a temperature of 80-100°C to obtain licorice extract. 7. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described centella asiatica extract is prepared by following method: Weigh 20-50g Centella asiatica, add 15-20 times the weight of Centella asiatica, soak in water for 0.25-0.80h, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; add to the filter residue 10-15 times the weight of the filter residue, heated to 90-100°C, decocted and extracted for 0.5-1.5h, and filtered to obtain the filtrate 2; then add 10-12 times the weight of the filter residue to the water, heated to 90-100°C, Decoct and extract for 0.5-1.5 hours, filter to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate to 5-8 times the weight of Centella asiatica at a temperature of 80-100°C to obtain Centella asiatica extract. 8. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described luffa extract is prepared by the following method: Weigh 100-200g of fresh loofah, cut into slices, add water 10-15 times the weight of loofah, heat to 90-100°C, decoct and extract for 0.5-1.5h, filter to obtain filtrate 1; add 10-15 Water twice the weight of the filter residue, heated to 90-100°C, decocted and extracted for 0.5-1.5h, filtered to obtain filtrate 2; then add water 10-12 times the weight of the filter residue to the filter residue, heated to 90-100°C, decocted and extracted 0.5-1.5h, filtrate to get filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate at a temperature of 80-100°C to 5-8 times the weight of the loofah to obtain the loofah extract. 9. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described angelica extract is prepared by the following method: Weigh 40-50g of angelica, crush it into coarse powder, add 10-16 times the weight of angelica in 75% ethanol solution, soak for 0.25-0.80h, reflux for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 1; Add 75% ethanol solution 10-15 times the weight of the filter residue, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 2; then add 75% ethanol solution 8-10 times the weight of the filter residue to the filter residue, reflux extraction 0.5- 1.5h, filter with 3 layers of gauze to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate under reduced pressure at a temperature of 40-50°C and a vacuum of 0.05-0.08Pa to 5-8% of the weight of angelica. times, that is the angelica extract. 10. the preparation method of a kind of emulsion for the treatment of keratosis pilaris according to claim 4, is characterized in that: described Cortex Moutan extract is prepared by the following method: Weigh 30-50g of Moutan Cortex, crush it into coarse powder, add 10-16 times the weight of Moutan Cortex 70% ethanol solution, soak for 0.25-0.80h, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 1; Add 70% ethanol solution 10-15 times the weight of the filter residue to the filter residue, reflux extraction for 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 2; then add 70% ethanol solution 8-10 times the weight of the filter residue to the filter residue, reflux extraction 0.5-1.5h, filter with 3 layers of gauze to obtain filtrate 3; combine filtrate 1, filtrate 2, and filtrate 3, and concentrate under reduced pressure at a temperature of 40-50°C and a vacuum of 0.05-0.08Pa to the weight of Moutan bark 5-8 times to get the Moutan cortex extract.