CN105031407B - It is a kind of to treat rheumatism, the Chinese medicine composition of rheumatoid, preparation method and application - Google Patents
It is a kind of to treat rheumatism, the Chinese medicine composition of rheumatoid, preparation method and application Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following mass parts: 100-700 parts of ant powder, 100-380 parts of American Ginseng, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis.The invention has the benefit that the Chinese medicine composition is curative for effect and uneasy to recur, decocts vast rheumatism, rheumatoid patient from illness, substantially increase quality of life.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of to treat rheumatism, the Chinese medicine composition of rheumatoid, its preparation
Method and application.
Background technique
Rheumatic and rheumatoid diseases belong to the scope of China's traditional Chinese medicine rheumatism, and cardinal symptom is muscle, joint, muscles and bones etc.
Pain, it is miserable, weigh, be numb, joint stuffiness or arthrocele, be one of the persistent ailment for seriously endangering human health, in recent years
Disease incidence rises year by year, and disability rate also rises year by year.The common therapeutic agent of rheumatic and rheumatoid diseases be nonsteroidal anti-inflammatory drug and
Hormone therapy, side effect is very big, and patient is difficult to be resistant to.
Summary of the invention
In order to solve the above problems existing in the present technology, the present invention provides a kind of Chinese medicines for treating rheumatism, rheumatoid
Composition, preparation method and application.
The technical scheme adopted by the invention is as follows: a kind of Chinese medicine composition for treating rheumatism, rheumatoid, by following mass parts
Raw material be made: 100-700 parts of ant powder, 100-380 parts of American Ginseng, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis.
Preferably, the Chinese medicine composition is made of the raw material of following mass parts: 300-500 parts of ant powder, American Ginseng
200-280 parts, 500-700 parts of Radix Astragali, 500-700 parts of semen coicis.
Preferably, the Chinese medicine composition is made of the raw material of following mass parts: 100-700 parts of ant powder, American Ginseng
100-380 parts, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis, 200-1000 parts of rhizoma polygonati, 100-700 parts of Radix Paeoniae Alba, elephant skin wood
200-1000 parts of melon, 50-550 parts of Radix Salviae Miltiorrhizae, 400-1200 parts of fructus lycii, 400-1200 parts of Chinese yam, 200-1000 parts of cortex cinnamomi and jujube
200-1000 parts.
Preferably, the Chinese medicine composition is made of the raw material of following mass parts: 300-500 parts of ant powder, American Ginseng
200-280 parts, 500-700 parts of Radix Astragali, 500-700 parts of semen coicis, 500-700 parts of rhizoma polygonati, 300-500 parts of Radix Paeoniae Alba, wrinkled papaya
500-700 parts, 200-400 parts of Radix Salviae Miltiorrhizae, 700-900 parts of fructus lycii, 700-900 parts of Chinese yam, 500-700 parts of cortex cinnamomi and jujube 500-
700 parts.
Preferably, the Chinese medicine composition is made of the raw material of following mass parts: 100-700 parts of ant powder, American Ginseng
100-380 parts, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis, 200-1000 parts of rhizoma polygonati, 100-700 parts of Radix Paeoniae Alba, elephant skin wood
200-1000 parts of melon, 50-550 parts of Radix Salviae Miltiorrhizae, 400-1200 parts of fructus lycii, 400-1200 parts of Chinese yam, 200-1000 parts of cortex cinnamomi and jujube
200-1000 parts, 4-8 parts of potassium sorbate, 2-4 parts of Aspartame and 3000-4000 parts of purified water.In the present invention, potassium sorbate
As preservative；Aspartame is as sweetener；Purified water is the conventional selection in industry as solvent, certainly, the present invention
Be not limited to it is selected above, any additive that can be played same or similar effect and meet relevant regulations can be used, until
In the selection of additive, belong to the prior art, those skilled in the art can be readily available, and details are not described herein again.
In order to better explain the present invention, below in the present invention raw material and compatibility relationship be further elaborated.
Ant powder, ant powder refer to that with Polyhachis vicina Roger (PolyrhachisvicinaRoger) be raw material drying grinding
At powder, have the abundant formic acid to antirheumatic, rheumatoid factor in Polyhachis vicina Roger body, it can penetrate seven, joint level, drop
The activity of low virus, Chinese medicine think that Polyhachis vicina Roger is a kind of mild tonic medicine, have and strengthen the body resistance to consolidate the constitution, promote longevity, mending
The effect of kidney and enhancing body, strengthening muscles and bones, eliminating blood stasis and smoothing collaterals.
American Ginseng, Classification system Panaxquinquefolius, alias American ginseng, American ginseng, Western ginseng, Chinese medicine think,
The effect of American Ginseng has Yin-nourishing and Qi-supplementing, and intelligence development of allaying excitement, clearing heat and promoting fluid, fall fire are relieved summer heat.American Ginseng has tonifying Qi and fall fire simultaneously
Double effects, therefore mend without it is dry be American Ginseng special feature.
Radix Astragali, Classification system Astragalusmembranaceus (Fisch.) Bunge, Radix Astragali have enhancing immunity of organism function
Energy, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial action.Radix Astragali can not only coronary artery dilator, improve
Myocardial blood supply improves immune function, and is capable of the process of delaying cell aging.
Semen coicis is the kind of gramineae Coixlacryma-jobiL.var.meyuan (Romen.) Stapf
Benevolence, alias rice benevolence, maize, Chuan Gu.Chinese medicine thinks that semen coicis has the effect of invigorating the spleen excreting dampness, remove numbness antidiarrheal.It is usually used in oedema, foot
The diseases such as gas, difficult urination, arthritis with fixed pain caused by dampness muscular constricture, splenasthenic diarrhea.
Rhizoma polygonati, Classification system Polygonatumsibiricum, be HUANGJING ZANYU CAPSULE, rhizome it is horizontal walk, cylindric, tubercle is swollen
Greatly.Impeller generator, stockless.It is general spring, the harvesting of two season of autumn, high-quality with autumn harvesting, after 3~4 year autumn overground part of cultivation is withered
Harvesting takes rhizome, removes aerial part and fibrous root, washes away soil, sets and is steamed in food steamer to when being presented glossy, taking-up is dried or dried
It is dry, or after setting and being boiled in water, pull out and dry or dry.Chinese medicine thinks that rhizoma polygonati is sweet in flavor mild-natured, there is boosting qi and nourishing yin, tonifying speen and tonifying kidney
Effect.It is usually used in weakness of the spleen and the stomach, fatigue and asthenia, dry deficiency of food, deficiency syndrome of the lung cough caused by dryness, asthenia of essence and blood, the diseases such as Heat Diabetes.
Radix Paeoniae Alba, Classification system Cynanchumotophyllum are the antianaemics in Chinese medicine.Bitter, acid；Cold nature；Return
Liver, the spleen channel.Chinese medicine thinks that Radix Paeoniae Alba enriches blood, holds back the effect of soft liver of yin, relieving spasm to stop pain.
Wrinkled papaya, Latin literary fame: Chaenomelesspeciosa (Sweet) Nakai, fruit contain malic acid, winestone
Acid, citric acid and vitamin C etc., are used as medicine after drying, have drive phoenix, relaxing muscles and tendons, active, analgesia, detumescence, it is pleasant the benefits of.For arranging
Myenteron spasm, vomiting and diarrhoea abdominal pain, rheumatic arthritis, soreness of waist and knee joint.
Radix Salviae Miltiorrhizae, Chinese medicine name.For the dry root and rhizome of Lamiaceae plant Radix Salviae Miltiorrhizae SalviamiltiorrhizaBge..Chinese medicine
Think, Radix Salviae Miltiorrhizae has the effect of promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.For chest impediment and cardialgia, stomach duct and abdomen hypochondriac pain,
The diseases such as the accumulation of lump in the abdomen lump in the abdomen, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea menostasis and sore swell and ache curative.
Fructus lycii, Latin literary fame: FRUCTUSLYCII is the ripening fruits of matrimony vine of solanaceae plant.It is adopted when summer, autumn fruit maturation
It plucks, removes carpopodium, set after shady place dries in the air to pericarp and corrugate, then be exposed to the sun to crust is stiff, pulp is soft to obtain the final product.Chinese medicine thinks,
Fructus lycii has effects that tonifying kidney and benefiting sperm, nourishes the liver to improve visual acuity, blood-enriching tranquillizing, promotes the production of body fluid to quench thirst, moistening lung to arrest cough, is used for liver-kidney Yin deficiency, waist and knee
Aching and limp, dizzy, dizzy, the more tears of blurred vision, cough due to consumptive disease, the diseases such as quench one's thirst and pass out semen.
Chinese yam, Latin literary fame: CommonYamRhizome, medicinal source are Dioscoreaceae plant Chinese yam dry rhizome.Chinese medicine
Think, Chinese yam have nourish it is strong, it is aid digestion, hold back abnormal sweating, the effect of antidiarrheal, cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes disappear
Yearningly, oliguria frequency, spermatorrhea, women's leukorrhagia and dyspeptic chronic enteritis.
Cortex cinnamomi, Classification system: CinnamomumcassiaPresl is the dry bark of lauraceae plant cortex cinnamomi.Chinese medicine is recognized
For cortex cinnamomi has effects that supplementing Yuanyang, warming spleen and stomach, removing internal cold, promoting blood circulation.Cure mainly the Yang-function insufficiency of kidneyzang, cold weak pulse of limb, yang depletion collapse,
Abdominal pain diarrhoea, cold hernia renal mass, waist and knee crymodynia, menostasis abdominal mass, negative subcutaneous ulcer, streamer, empty sun are floating more and heat in the upper and cold in the lower.
Jujube, Classification system: jujube is Rhamnaceae jujube jujube ZiziphusjujubaMill.var.inermis
(Bunge) dry mature fruit of Rehd..It harvests, dries when the fruit matures in the fall to obtain the final product.Chinese medicine thinks that jujube has tonifying spleen
The effect of QI invigorating and mental-tranquilization.For splenasthenic diarrhea, palpitaition, insomnia and night sweat.
The effect of raw material in the present invention are as follows: present invention uses ant powders, are made using formic acid abundant in ant powder
To be aided with the Yin-nourishing and Qi-supplementing of American Ginseng to antirheumatic, rheumatoid factor, the effect of intelligence development of allaying excitement, clearing heat and promoting fluid, fall fire are relieved summer heat；
With the improvement myocardial blood supply of Radix Astragali, immune function is improved；Along with the invigorating the spleen excreting dampness of semen coicis, the effect of remove numbness antidiarrheal, generate
The compound effect of excellent treatment rheumatism, rheumatoid.
Meanwhile the effect of being aided with rhizoma polygonati boosting qi and nourishing yin, tonifying speen and tonifying kidney；Radix Paeoniae Alba enriches blood, holds back the effect of negative soft liver；Wrinkled papaya
The effect of driving phoenix, relaxing muscles and tendons；The effect of Radix Salviae Miltiorrhizae promoting blood circulation, cool blood to disappear carbuncle；The effect of fructus lycii tonifying kidney and benefiting sperm, Chinese yam nourish it is strong,
The effect of holding back abnormal sweating；The effect of cortex cinnamomi supplementing Yuanyang, removing internal cold.After the effect of jujube invigorates the spleen and benefits qi, mental-tranquilization, further enhance
The drug effect of Chinese medicine composition, plays better therapeutic effect in the present invention.
Potassium sorbate, scientific name 2,4- potassium hexadiene, be it is colourless to white flakes shape crystallization or crystalline powder, it is odorless or
Slightly stink.Belong to acidic preservative, is mainly used as the preservative of food and medicine.
Aspartame, also known as aspartame are a kind of artificial sweeteners of non-carbohydrate class.Aspartame is a kind of
Natural function oligosaccharide, will not saprodontia, sweet taste is pure, hygroscopicity is low, without stickiness, the obvious liter of blood glucose will not be caused
Height is suitble to patients with diabetes mellitus, is usually used in the sweetener of food, drug.
Purified water, be drinking water through made from the way of distillation, ion-exchange, hyperfiltration or other suitable methods for medicine
Water is free of any additive, is commonly used for the solvent of drug.
The present invention also provides a kind of preparation methods of above-mentioned Chinese medicine composition, comprising the following steps:
(1) it extracts: the ant powder being added after ethyl alcohol impregnates and filters to take filtrate, obtains ant powder ethanol solution, it will be described
Ant powder ethanol solution evaporation solvent obtains concentrate I, then surplus stock addition purified water is decocted, and filters to take filtrate and steams
Hair solvent obtains raw material dissolution fluid, then adds people's ethyl alcohol to the raw material dissolution fluid, filters to take filtrate after standing, obtains ethanol extract,
Ethanol extract evaporation solvent is obtained into concentrate II；
(2) it prepares: the concentrate I and concentrate II being uniformly mixed, original liquid is obtained；It will be described with a part of purified water
After potassium sorbate and Aspartame dissolution, it is added in the original liquid, then remaining purified water is added in the original liquid,
Stirring filters to take filtrate after standing to get finished product medical fluid.
It preferably, further include (3) sterilization filling after step (2) are prepared: the temperature by the finished product medical fluid at 100-110 DEG C
It degree lower sterilizing 20-40 minutes, is cooled to room temperature, it is filling, it is packed after lamp inspection.It can directly encapsulate, save after sterilization filling, and throw
Put market.
Preferably, the ant powder is impregnated using the ethyl alcohol that mass fraction is 70% in step (1) extraction, ethyl alcohol
Quality be 6-10 times of the ant powder quality, soaking time is 90-150 hours；It filters to take ant powder filter residue after filtrate
Refluxing extraction is carried out using the ethyl alcohol that mass fraction is 70%, the quality of ethyl alcohol is 6-10 times of the ant powder filter residue quality,
Refluxing extraction temperature is 70-78 DEG C, and reflux extracting time is 1-3 hours；The filtrate obtained after immersion and refluxing extraction are obtained
Extracting solution after mixing ant powder ethanol solution；The concentrate I is 1.04-1.06 in 50 DEG C of relative density；It will
It when surplus stock addition purified water is decocted, carries out in two times, for the first time plus the quality of purified water is surplus stock quality
6-10 times, decocting time is 1-3 hours, second plus the quality of purified water is 4-8 times of surplus stock quality, and decocting time is
1-3 hours；Will the filtrate that obtained twice mix after evaporation solvent obtain raw material dissolution fluid, the raw material dissolution fluid is opposite at 60 DEG C
Density is 1.12-1.18, then the raw material dissolution fluid is added people's ethyl alcohol, obtains the system that ethyl alcohol mass fraction is 50-70%, quiet
After setting 18-30 hours, filtrate is filtered to take, obtains ethanol extract, ethanol extract evaporation solvent is obtained into concentrate II.Using
Above-mentioned parameter, the active constituent in raw material can be proposed more thoroughly, chemical reagent, temperature, time and solvent evaporation amount
Selection is inventor by the optimal selection that under the premise of carefully analyzing physical property, takes into account product quality and production cost is made.Its
The comparison object of middle relative density is purified water.
It should be noted that should not be used as because the ethyl alcohol that mass fraction is 70% is selected as a kind of commonly concentration
Limitation of the invention, those skilled in the art are easy to reach same effect by using the ethyl alcohol of various concentration, herein
Just repeat no more.
Preferably, mixing time is 20-40 minutes in step (2) preparation, and time of repose is 18-30 hours.It stirs herein
Under time and time of repose, it is ensured that sufficiently dissolution and standing finish, and guarantee the quality of finished product medical fluid.
The invention also discloses application of the above-mentioned Chinese medicine composition in preparation treatment rheumatism, antirheumatic, the medicines
Object is medically acceptable any preparation.
The invention has the benefit that
1, the present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, curative for effect and uneasy to recur, make wide
Big rheumatism, rheumatoid patient are decocted from illness, substantially increase quality of life.
2, the present invention provides a kind of Chinese medicine composition for treating rheumatism, rheumatoid, with traditional nonsteroidal anti-inflammatory drug and
Hormonal medicaments are compared, and curative effect is obvious and Small side effects, patient are easier to receive.
Specific embodiment
Embodiment 1
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 100g, American Ginseng 100g, Radix Astragali 200g, semen coicis 200g.
Embodiment 2
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 700g, American Ginseng 380g, Radix Astragali 1000g, semen coicis 1000g.
Embodiment 3
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 400g, American Ginseng 240g, Radix Astragali 600g, semen coicis 600g.
Embodiment 4
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 300g, American Ginseng 200g, Radix Astragali 500g, semen coicis 500g.
Embodiment 5
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 500g, American Ginseng 280g, Radix Astragali 700g, semen coicis 700g.
Embodiment 6
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 100g, American Ginseng 100g, Radix Astragali 200g, semen coicis 200g, rhizoma polygonati 200g, Radix Paeoniae Alba 100g, wrinkled papaya 200g, Radix Salviae Miltiorrhizae 50g,
Fructus lycii 400g, Chinese yam 400g, cortex cinnamomi 200g, jujube 200g.
Embodiment 7
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 700g, American Ginseng 380g, Radix Astragali 1000g, semen coicis 1000g, rhizoma polygonati 1000g, Radix Paeoniae Alba 700g, wrinkled papaya 1000g, Radix Salviae Miltiorrhizae
550g, fructus lycii 1200g, Chinese yam 1200g, cortex cinnamomi 1000g, jujube 1000g.
Embodiment 8
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 400g, American Ginseng 240g, Radix Astragali 600g, semen coicis 600g, rhizoma polygonati 600g, Radix Paeoniae Alba 400g, wrinkled papaya 600g, Radix Salviae Miltiorrhizae
300g, fructus lycii 800g, Chinese yam 800g, cortex cinnamomi 600g, jujube 600g.
Embodiment 9
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 300g, American Ginseng 200g, Radix Astragali 500g, semen coicis 500g, rhizoma polygonati 500g, Radix Paeoniae Alba 300g, wrinkled papaya 500g, Radix Salviae Miltiorrhizae
200g, fructus lycii 700g, Chinese yam 700g, cortex cinnamomi 500g, jujube 500g.
Embodiment 10
The present invention provides a kind of Chinese medicine compositions for treating rheumatism, rheumatoid, are made of the raw material of following quality: ant
Powder 500g, American Ginseng 280g, Radix Astragali 700g, semen coicis 700g, rhizoma polygonati 700g, Radix Paeoniae Alba 500g, wrinkled papaya 700g, Radix Salviae Miltiorrhizae
400g, fructus lycii 900g, Chinese yam 900g, cortex cinnamomi 700g, jujube 700g.
Embodiment 11
The present invention also provides a kind of methods for preparing above-mentioned Chinese medicine composition, comprising the following steps:
(1) it extracts: the ant powder impregnating the ant powder using the ethyl alcohol that mass fraction is 70%, ethyl alcohol
Quality be 6 times of the ant powder quality, soaking time is 90 hours；It filters to take and ant powder filter residue is used into quality after filtrate
The ethyl alcohol that score is 70% carries out refluxing extraction, and the quality of ethyl alcohol is 6 times of the ant powder filter residue quality, refluxing extraction temperature
It is 70 DEG C, reflux extracting time is 1 hour；The extracting solution that the filtrate obtained after immersion and refluxing extraction are obtained is after mixing
Obtain ant powder ethanol solution；Ant powder ethanol solution evaporation solvent is obtained into concentrate I, phase of the concentrate I at 50 DEG C
It is 1.04 to density, then surplus stock addition purified water is decocted, when surplus stock addition purified water is decocted, point
It carries out twice, for the first time plus the quality of purified water is 6 times of surplus stock quality, and decocting time is 1 hour, second plus purifying
The quality of water is 4 times of surplus stock quality, and decocting time is 1 hour；Evaporation solvent obtains after the filtrate obtained twice is mixed
Raw material dissolution fluid, the raw material dissolution fluid are 1.12 in 60 DEG C of relative density, obtain the system that ethyl alcohol mass fraction is 50%,
After standing 18 hours, filtrate is filtered to take, ethanol extract is obtained, ethanol extract evaporation solvent is obtained into concentrate II；
(2) it prepares: the concentrate I and concentrate II being uniformly mixed, original liquid is obtained；It will be described with a part of purified water
After potassium sorbate and Aspartame dissolution, it is added in the original liquid, then remaining purified water is added in the original liquid,
Stirring 20 minutes filters to take filtrate after standing 18 hours to get finished product medical fluid.
(3) sterilization filling: by the finished product medical fluid 100 DEG C at a temperature of sterilize 20 minutes, be cooled to room temperature, it is filling,
It is packed after lamp inspection.
Embodiment 12
The present invention also provides a kind of methods for preparing above-mentioned Chinese medicine composition, comprising the following steps:
(1) it extracts: the ant powder impregnating the ant powder using the ethyl alcohol that mass fraction is 70%, ethyl alcohol
Quality be 10 times of the ant powder quality, soaking time is 150 hours；It filters to take and ant powder filter residue is used into matter after filtrate
It measures the ethyl alcohol that score is 70% and carries out refluxing extraction, the quality of ethyl alcohol is 10 times of the ant powder filter residue quality, refluxing extraction
Temperature is 78 DEG C, and reflux extracting time is 3 hours；The extracting solution that the filtrate obtained after immersion and refluxing extraction are obtained mixes equal
Ant powder ethanol solution is obtained after even；Ant powder ethanol solution evaporation solvent is obtained into concentrate I, the concentrate I is at 50 DEG C
Relative density be 1.06, then by surplus stock addition purified water decoct, by surplus stock addition purified water decoct
When, it carries out in two times, for the first time plus the quality of purified water is 10 times of surplus stock quality, and decocting time is 3 hours, second
Adding the quality of purified water is 8 times of surplus stock quality, and decocting time is 3 hours；It is evaporated after the filtrate obtained twice is mixed
Solvent obtains raw material dissolution fluid, and the raw material dissolution fluid is 1.18 in 60 DEG C of relative density, and obtaining ethyl alcohol mass fraction is 70%
System, stand 30 hours after, filter to take filtrate, obtain ethanol extract, by the ethanol extract evaporation solvent obtain concentrate
II；
(2) it prepares: the concentrate I and concentrate II being uniformly mixed, original liquid is obtained；It will be described with a part of purified water
After potassium sorbate and Aspartame dissolution, it is added in the original liquid, then remaining purified water is added in the original liquid,
Stirring 40 minutes filters to take filtrate after standing 30 hours to get finished product medical fluid.
(3) sterilization filling: by the finished product medical fluid 110 DEG C at a temperature of sterilize 40 minutes, be cooled to room temperature, it is filling,
It is packed after lamp inspection.
Embodiment 13
The present invention also provides a kind of methods for preparing above-mentioned Chinese medicine composition, comprising the following steps:
(1) it extracts: the ant powder impregnating the ant powder using the ethyl alcohol that mass fraction is 70%, ethyl alcohol
Quality be 8 times of the ant powder quality, soaking time is 120 hours；It filters to take and ant powder filter residue is used into matter after filtrate
It measures the ethyl alcohol that score is 70% and carries out refluxing extraction, the quality of ethyl alcohol is 8 times of the ant powder filter residue quality, refluxing extraction temperature
Degree is 74 DEG C, and reflux extracting time is 2 hours；The extracting solution that the filtrate obtained after immersion and refluxing extraction obtain is uniformly mixed
Ant powder ethanol solution is obtained afterwards；Ant powder ethanol solution evaporation solvent is obtained into concentrate I, the concentrate I is at 50 DEG C
Relative density is 1.05, then surplus stock addition purified water is decocted, when surplus stock addition purified water is decocted,
It carries out in two times, for the first time plus the quality of purified water is 8 times of surplus stock quality, and decocting time is 2 hours, for the second time plus pure
The quality for changing water is 6 times of surplus stock quality, and decocting time is 2 hours；Solvent is evaporated after the filtrate obtained twice is mixed
Raw material dissolution fluid is obtained, the raw material dissolution fluid is 1.15 in 60 DEG C of relative density, obtains the body that ethyl alcohol mass fraction is 60%
System filters to take filtrate, obtains ethanol extract after standing 24 hours, and ethanol extract evaporation solvent is obtained concentrate II；
(2) it prepares: the concentrate I and concentrate II being uniformly mixed, original liquid is obtained；It will be described with a part of purified water
After potassium sorbate and Aspartame dissolution, it is added in the original liquid, then remaining purified water is added in the original liquid,
Stirring 30 minutes filters to take filtrate after standing 24 hours to get finished product medical fluid.
(3) sterilization filling: by the finished product medical fluid 105 DEG C at a temperature of sterilize 30 minutes, be cooled to room temperature, it is filling,
It is packed after lamp inspection.
Embodiment 14
The present embodiment is the clinical test to the Chinese medicine composition in the present invention
(1), testing crew general information
Select various rheumatism, the rheumatoid patient 400 made a definite diagnosis through hospital, in which: male 200, women 200；Year
Age 21~65 years old, average age 46 years old.In 400 patients, rheumatoid arthritis patients are 299 people；Whole body rheumatic arthritis is suffered from
Person is 68 people；Depositing old property damage is 33 people.
(2), testing crew diagnosis basis
With " Chinese medical disease Standardization of diagnosis and curative effect (ZY/T001.1-94) " be standard, with clinical manifestation, hospital diagnosis conclusion,
The data such as B ultrasound report are foundation, are referred to, and Other diseases are excluded.
(3), test method
Using the composition in embodiment 8, finished product made from the method in embodiment 13, the wherein dose in embodiment 8
It is 1000 parts, daily three parts, each portion in the morning, afternoon and evening.It continuously takes 180 days, the during which withdrawal if recovery from illness.
(4), test result and conclusion
It is provided by the invention treatment rheumatism, the traditional Chinese medicine composition for treating calculus of rheumatoid cure rate be 89.5%, always have
Efficiency is 99.0%, illustrates that Chinese medicine composition of the invention all has exact curative effect to treatment rheumatism, rheumatoid.
The present invention is not limited to above-mentioned preferred forms, anyone can show that other are various under the inspiration of the present invention
The product of form, however, make any variation in its shape or structure, it is all that there is skill identical or similar to the present application
Art scheme, is within the scope of the present invention.
Claims (8)
1. a kind of Chinese medicine composition for treating rheumatism, rheumatoid, which is characterized in that be made of the raw material of following mass parts: ant
It is 100-700 parts of powder, 100-380 parts of American Ginseng, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis, 200-1000 parts of rhizoma polygonati, white
100-700 parts of Chinese herbaceous peony, 200-1000 parts of wrinkled papaya, 50-550 parts of Radix Salviae Miltiorrhizae, 400-1200 parts of fructus lycii, 400-1200 parts of Chinese yam, meat
Osmanthus 200-1000 parts and jujube 200-1000 parts.
2. Chinese medicine composition according to claim 1, which is characterized in that be made of the raw material of following mass parts: ant powder
300-500 parts, 200-280 parts of American Ginseng, 500-700 parts of Radix Astragali, 500-700 parts of semen coicis, 500-700 parts of rhizoma polygonati, Radix Paeoniae Alba
300-500 parts, 500-700 parts of wrinkled papaya, 200-400 parts of Radix Salviae Miltiorrhizae, 700-900 parts of fructus lycii, 700-900 parts of Chinese yam, cortex cinnamomi
500-700 parts and jujube 500-700 parts.
3. a kind of Chinese medicine composition for treating rheumatism, rheumatoid, which is characterized in that be made of the raw material of following mass parts: ant
It is 100-700 parts of powder, 100-380 parts of American Ginseng, 200-1000 parts of Radix Astragali, 200-1000 parts of semen coicis, 200-1000 parts of rhizoma polygonati, white
100-700 parts of Chinese herbaceous peony, 200-1000 parts of wrinkled papaya, 50-550 parts of Radix Salviae Miltiorrhizae, 400-1200 parts of fructus lycii, 400-1200 parts of Chinese yam, meat
Osmanthus 200-1000 parts, 200-1000 parts of jujube, 4-8 parts of potassium sorbate, 2-4 parts of Aspartame and 3000-4000 parts of purified water.
4. a kind of preparation method of Chinese medicine composition according to claim 3, which comprises the following steps:
(1) it extracts: the ant powder being added after ethyl alcohol impregnates and filters to take filtrate, ant powder ethanol solution is obtained, by the ant
Powder ethanol solution evaporation solvent obtains concentrate I, then surplus stock addition purified water is decocted, and filters to take filtrate and evaporates molten
Agent obtains raw material dissolution fluid, then adds people's ethyl alcohol to the raw material dissolution fluid, filters to take filtrate after standing, obtains ethanol extract, by institute
It states ethanol extract evaporation solvent and obtains concentrate II；
(2) it prepares: the concentrate I and concentrate II being uniformly mixed, original liquid is obtained；With a part of purified water by the sorb
After sour potassium and Aspartame dissolution, it is added in the original liquid, then remaining purified water is added in the original liquid, stirs
Filtrate is filtered to take after standing to get finished product medical fluid.
5. the preparation method according to claim 4, which is characterized in that further include after step (2) are prepared
(3) sterilization filling: by the finished product medical fluid 100-110 DEG C at a temperature of sterilize 20-40 minute, be cooled to room temperature, filling
It fills, is packed after lamp inspection.
6. the preparation method according to claim 4, which is characterized in that using mass fraction in step (1) extraction is 70%
Ethyl alcohol the ant powder is impregnated, the quality of ethyl alcohol is 6-10 times of the ant powder quality, soaking time 90-
150 hours；It filters to take and ant powder filter residue is subjected to refluxing extraction, the matter of ethyl alcohol using the ethyl alcohol that mass fraction is 70% after filtrate
Amount is 6-10 times of the ant powder filter residue quality, and refluxing extraction temperature is 70-78 DEG C, and reflux extracting time is 1-3 hours；It will
The extracting solution that the filtrate and refluxing extraction obtained after immersion obtains obtains ant powder ethanol solution after mixing；The concentrate I
Relative density be 1.04-1.06；It when surplus stock addition purified water is decocted, carries out, for the first time plus purifies in two times
The quality of water is 6-10 times of surplus stock quality, and decocting time is 1-3 hours, second plus the quality of purified water is remaining former
4-8 times for expecting quality, decocting time are 1-3 hours；Evaporation solvent obtains raw material dissolution fluid, institute after the filtrate obtained twice is mixed
The relative density for stating raw material dissolution fluid is 1.12-1.18, then the raw material dissolution fluid is added people's ethyl alcohol, obtains ethyl alcohol mass fraction
Filtrate is filtered to take, ethanol extract is obtained, the ethanol extract is evaporated after standing 18-30 hours for the system of 50-70%
Solvent obtains concentrate II.
7. the preparation method according to claim 4, which is characterized in that mixing time is 20-40 points in step (2) preparation
Clock, time of repose are 18-30 hours.
8. application of the Chinese medicine composition of any of claims 1 or 2 in preparation treatment rheumatism, antirheumatic, the drug
For medically acceptable any preparation.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN103566236A (en) * | 2013-11-08 | 2014-02-12 | 广西双蚁药业有限公司 | Traditional Chinese medicinal preparation for dispelling dampness and soothing channel |
| CN103599425A (en) * | 2013-11-08 | 2014-02-26 | 广西双蚁药业有限公司 | Novel double-ant capsule for clearing dampness and dredging collaterals |
| CN104146201A (en) * | 2014-08-18 | 2014-11-19 | 胡安然 | Total nutrient formulation food for patients with rheumatoid arthritis |
-
2015
- 2015-08-27 CN CN201510536691.1A patent/CN105031407B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1354014A (en) * | 2001-11-29 | 2002-06-19 | 廖干甫 | Gongbu ointment |
| CN103566236A (en) * | 2013-11-08 | 2014-02-12 | 广西双蚁药业有限公司 | Traditional Chinese medicinal preparation for dispelling dampness and soothing channel |
| CN103599425A (en) * | 2013-11-08 | 2014-02-26 | 广西双蚁药业有限公司 | Novel double-ant capsule for clearing dampness and dredging collaterals |
| CN104146201A (en) * | 2014-08-18 | 2014-11-19 | 胡安然 | Total nutrient formulation food for patients with rheumatoid arthritis |
Non-Patent Citations (1)
| Title |
|---|
| 中医药治疗类风湿性关节炎进展;樊冰;《山东中医药大学学报》;19970331;第21卷(第2期);152-154 * |
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