CN106074765A - A kind of Chinese medicine composition of sleep of calming the nerves, help - Google Patents
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/52—Juglandaceae (Walnut family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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Abstract
A kind of Chinese medicine composition of sleep of calming the nerves, help, according to the raw material of parts by weight be: Semen Juglandis 15 25 parts, Semen Ziziphi Spinosae 15 20 parts, Caulis Polygoni Multiflori 10 15 parts, Radix Polygalae 5 15 parts, Fructus Jujubae 5 10 parts.Each raw material is carried out drying and crushing respectively sieve mixing of weighing, obtains fine powder, standby；In fine powder, add vinegar, after stirring, use slow fire fried dry, obtain Chinese medicine composition.The traditional Chinese medicine composite of the present invention is pure Chinese medicine, has no side effect；Therapeutic effect is notable, treatment cycle is short；It addition, this Chinese medicine composition preparation method is simple, with low cost.
Description
Technical field
The present invention relates to Chinese medicine preparation field, the Chinese medicine composition of a kind of sleep of calming the nerves, help.
Background technology
Having all one's life of people spend in sleep, human body supplements energy in sleep, strengthens and support time of 1/3rd
Drag, promotion normal growth growth, consolidating memory, holding attention and the alleviation unhealthy emotion such as anxiety, anxiety.Do not have enough sleep meeting
Cause elaborative faculty to decline, immunologic function reduces, affect normal development, even cause other diseases.Along with the progress of society, people
Be faced with huge life stress, operating pressure, insomnia has become as the stealthy killer of human health.
Treatment sleeping problems mainly use oral sleeping pill and the method for sleeping medicine at present, although short-period used has certain
Effect, but life-time service not only can affect normal sleep pattern, and can develop immunity to drugs, it is also possible to make health and psychology be formed
Dependency, even produces sequela.Some Traditional Chinese medicine healthcare drug are currently also had to occur, but because mouthfeel is poor, curative effect length, preparation method
Complexity, is not accepted.
Summary of the invention
It is an object of the invention to the deficiency for solving above-mentioned technical problem, it is provided that a kind of curative effect is high, in good taste, side effect is little
The Chinese medicine composition of sleep of calming the nerves, help；This Chinese medicine composition has Anshen Bunao, QI invigorating nourishing, raising immunity, improves and sleep
The curative effect of dormancy quality.
For achieving the above object, the present invention provides following technical scheme:
A kind of Chinese medicine composition of sleep of calming the nerves, help, according to the raw material of parts by weight be: Semen Juglandis 15-25 part, Semen Ziziphi Spinosae 15-20
Part, Caulis Polygoni Multiflori 10-15 part, Radix Polygalae 5-15 part, Fructus Jujubae 5-10 part.
As the further scheme of the present invention, described in calm the nerves, help the Chinese medicine composition of sleep, according to the raw material of parts by weight
For: Semen Juglandis 20 parts, Semen Ziziphi Spinosae 18 parts, Caulis Polygoni Multiflori 12 parts, Radix Polygalae 9 parts, Fructus Jujubae 8 parts.
The preparation method of the Chinese medicine composition of a kind of sleep of calming the nerves, help, concretely comprises the following steps: (1) is by Semen Juglandis, Semen Ziziphi Spinosae, head
Wu Teng, Radix Polygalae, Fructus Jujubae are carried out-are dried-pulverize-cross 200 mesh sieves-weigh-mix respectively, obtain fine powder, standby；(2) exist
The fine powder that step (1) obtains adds 50-100 part vinegar, after stirring, uses slow fire fried dry, obtain Chinese medicine composition.
As the further scheme of the present invention, step (2) adds 65 parts of vinegars in the fine powder that step (1) obtains, stirring
After Jun Yun, use slow fire fried dry, obtain Chinese medicine composition.
The theoretical foundation of the present invention is:
Semen Juglandis: sweet in the mouth, property are flat, temperature, nontoxic, micro-hardship, micro-puckery.Semen Juglandis sweet in the mouth, warm in nature, enter kidney, lung, large intestine channel.Can the kidney invigorating, controlling nocturnal emission with astringent drugs
Strong waist, warming the lung Dingchuan, loosening bowel to relieve constipation.Cure mainly: suffer from a deficiency of the kidney breathe heavily cough, lumbago.Often food can health invigorating, moisten flesh, supplementing the brain, black beard and hair.
Semen Ziziphi Spinosae: nature and flavor: sweet is flat.1. " herbal classic ": " sour in the mouth, flat." 2. " not Lu ": " nontoxic." 3. amplification on Canon of Materia Medica: micro-
Temperature.4. principle of Correct Diet: " sour in the mouth is sweet, flat." return through: enter the heart, spleen, liver, gallbladder meridian.1. " detailed outline ": " foot is fainted cloudy, few positive." 2. " thunder
Public process of preparing Chinese medicine property of medicine solution ": " enter the heart, spleen, liver, gallbladder four warp." function cures mainly: nourishing the liver, mind calming, calm the nerves, arresting sweating.Control restlessness of asrhenia type and insomnia, frightened
Throb with fear palpitation with a distress feeling, excessive thirst, sweating due to debility.
Caulis Polygoni Multiflori: nature and flavor: sweet is flat.Gui Jing: GUIXIN, Liver Channel.Function with cure mainly: nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.For losing
Dormancy dreaminess, blood deficiency general pain, rheumatic arthralgia；External treatment skin pruritus.
Radix Polygalae: nature and flavor: toil, temperature.1. " herbal classic ": " bitter in the mouth, temperature." 2. " not Lu ": " nontoxic." 3. " Bencao Jingshu ": " bitter
Micro-pungent, temperature." 4. " Records of Tradition Chinese and Western Medicine in Combination ": " acid is micro-pungent, and property is put down." return through: enter the heart, kidney channel.1. Wang Haogu: " kidney channel edema caused by disorder of QI.”
2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " enter the heart, liver, spleen three warp." function cures mainly: Fructus Alpiniae Oxyphyllae of calming the nerves, eliminate the phlegm, resolving depression.Control palpitation with fear, forgetful, nocturnal emission, loses
Sleeping, cough ant phlegm, carbuncle skin ulcer swells.
Fructus Jujubae: nature and flavor: sweet, temperature.1. " herbal classic ": " sweet in the mouth, flat." 2. " a thousand pieces of gold dietetic therapy ": " sweet in the mouth is pungent, heat, nontoxic." 3. Meng
Numerous: " temperature." return through: enter spleen, stomach warp.1. " detailed outline ": " spleen channel blood system." 2. " Bencao Jingshu ": " enter foot lunar, Yangming Channel." merit
With curing mainly: spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, adjust battalion to defend, solve poison of drug.Controlling insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid is not enough, and battalion defends
Discord, severe palpitation.Married woman's stolen goods are hot-tempered.
Compared with prior art, the invention has the beneficial effects as follows:
The traditional Chinese medicine composite of the present invention is pure Chinese medicine, safety non-toxic, is suitable for long-term taking；Therapeutic effect is notable, treatment week
Phase is short；It addition, this Chinese medicine composition preparation method is simple, with low cost.
Detailed description of the invention
Below in conjunction with detailed description of the invention, the technical scheme of this patent is described in more detail.
Embodiment 1
The preparation method of the Chinese medicine composition of a kind of sleep of calming the nerves, help, concretely comprises the following steps: (1) is by Semen Juglandis 15 parts, Semen Ziziphi Spinosae 15
Part, Caulis Polygoni Multiflori 10 parts, Radix Polygalae 5 parts, Fructus Jujubae 5 parts are carried out-are dried-pulverize-cross 200 mesh sieves-weigh-mix respectively, obtain
Fine powder, standby；(2) in the fine powder that step (1) obtains, add 50 parts of vinegars, after stirring, use slow fire fried dry, obtain Chinese medicine
Compositions.
Embodiment 2
The preparation method of the Chinese medicine composition of a kind of sleep of calming the nerves, help, concretely comprises the following steps: (1) is by Semen Juglandis 25 parts, Semen Ziziphi Spinosae 20
Part, Caulis Polygoni Multiflori 15 parts, Radix Polygalae 15 parts, Fructus Jujubae 10 parts are carried out-are dried-pulverize-cross 200 mesh sieves-weigh-mix respectively,
To fine powder, standby；(2) in the fine powder that step (1) obtains, add 100 parts of vinegars, after stirring, use slow fire fried dry, to obtain final product
Chinese medicine composition.
Embodiment 3
The preparation method of the Chinese medicine composition of a kind of sleep of calming the nerves, help, concretely comprises the following steps: (1) is by Semen Juglandis 20 parts, Semen Ziziphi Spinosae 18
Part, Caulis Polygoni Multiflori 12 parts, Radix Polygalae 9 parts, Fructus Jujubae 8 parts are carried out-are dried-pulverize-cross 200 mesh sieves-weigh-mix respectively, obtain
Fine powder, standby；(2) in the fine powder that step (1) obtains, add 65 parts of vinegars, after stirring, use slow fire fried dry, obtain Chinese medicine
Compositions.
One, toxicity test:
Laboratory animal: white mice, provided by Hefei City's animal experimental center.
Mice lavage administration acute toxicity test:
Test method: after 40 white mice adaptabilities in laboratory conditions are fed 10 days, be randomly divided into 2 groups, i.e. experimental group
And matched group, often group 20.After fasting 12h (can't help water), experimental group gives the Chinese medicine gavage prepared such as embodiment 3, right
Normal saline gavage is given according to group.The situation such as observe the spirit of white mice after gavage in seven days, behavior, diet are intended to, records little Bai
Mus death time and quantity, cut open the dead white mice of inspection, observe the pathological change of each organs and tissues.
Experimental result: none death of white mice in seven days, puts to death each internal organs of white mice anatomic observation and does not finds toxic reaction,
Experimental group and matched group white mice are without any difference.
Wistar rat oral gavage administration long term toxicity test:
Test method:
(1) choose wistar rat 40, be divided into two groups, i.e. matched group, experimental group, often group 20.
(2) experimental group gives the Chinese medicine gavage prepared such as embodiment 3, and dosage is 5 times of adult's medication, and matched group is given
Give normal saline gavage, gavage three times on the one, successive administration 60 days, observe the index such as animal ordinary circumstance and body weight.Drug withdrawal three
After it, observe the indexs such as the spirit of wistar rat, behavior, diet desire, body weight.
Result of the test:
The indexs such as the spirit of wistar rat, behavior, diet desire, body weight have no significant change.Put to death rat, its internal organs are carried out
Tissue slice, shows without any pathological changes and exception under Electronic Speculum.
Clinical laboratory data:
1. the selection of patient: for showing the therapeutic effect of Chinese medicine of the present invention, in clinical trial, selecting 150 has sleeping problems
Patient as treatment group.The maleest 80 examples, female 70 example；Age is between 20-70 year.Symptom is: the most difficult sleep, spirit is withered
Wasting, hypomnesis, headache, lumbago, inappetence, alopecia, face turns to be yellow.
3. test method:
150 patients are divided into 3 groups, and i.e. experimental group 1, experimental group 2, experimental group 3, often organize 50 people.
(1) the oral Chinese medicine produced by the embodiment of the present invention 1 of experimental group 1, three times on the one, a 10g, after meal clothes half an hour
With, within 10 days, it is a course for the treatment of；
(2) the oral Chinese medicine produced by the embodiment of the present invention 2 of experimental group 2, three times on the one, a 10g, take half an hour after meal,
It within 10 days, it is a course for the treatment of；
(3) the oral Chinese medicine produced by the embodiment of the present invention 3 of experimental group 3, three times on the one, a 10g, take half an hour after meal,
It within 10 days, it is a course for the treatment of.
2. curative effect judgment criteria:
(1) effective: after 2-3 the course for the treatment of, described symptom disappears substantially, enters sleep in 30 minutes, and face recovers ruddy；
(2) effective: after 3-4 the course for the treatment of, described symptom alleviates, complexion is improved；
(3) invalid: after 3-5 the course for the treatment of, described symptom does not alleviates or increases the weight of.
4. clinical trial results:
(1) experimental group 1 effective 35, effective 50, invalid 0, effective percentage 100%；
(2) experimental group 2 effective 39, effective 50, invalid 0, effective percentage 100%；
(3) experimental group 3 effective 45, effective 50, invalid 0, effective percentage 100%.
Test result indicate that: the Chinese medicine composition that three embodiments of the present invention prepare has well calms the nerves, helps sleep
Effect, can effectively treat the various symptoms caused because of sleeping problems, and clinical effective rate reaches 100%, and the best results of embodiment 3,
Obvious effective rate reaches 90%.The Chinese medicine composition of the sleep of calming the nerves, help of the present invention is safely and effectively.
Above the better embodiment of this patent is explained in detail, but this patent is not limited to above-mentioned embodiment party
Formula, in the ken that one skilled in the relevant art is possessed, it is also possible on the premise of without departing from this patent objective
Make a variety of changes.
Claims (4)
1. the Chinese medicine composition of a sleep of calming the nerves, help, it is characterised in that according to the raw material of parts by weight be: Semen Juglandis 15-25
Part, Semen Ziziphi Spinosae 15-20 part, Caulis Polygoni Multiflori 10-15 part, Radix Polygalae 5-15 part, Fructus Jujubae 5-10 part.
The Chinese medicine composition of sleep of calming the nerves, help the most according to claim 1, it is characterised in that former according to parts by weight
Material is: Semen Juglandis 20 parts, Semen Ziziphi Spinosae 18 parts, Caulis Polygoni Multiflori 12 parts, Radix Polygalae 9 parts, Fructus Jujubae 8 parts.
The preparation method of the Chinese medicine composition of a kind of sleep of calming the nerves, help the most according to claim 1 and 2, it is characterised in that
Concretely comprise the following steps: (1) Semen Juglandis, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Radix Polygalae, Fructus Jujubae are carried out respectively-are dried-pulverizes-cross 200 mesh sieves-
Weigh-mix, obtain fine powder, standby；(2) in the fine powder that step (1) obtains, add 50-100 part vinegar, use slow fire fried dry,
Obtain Chinese medicine composition.
The preparation method of the Chinese medicine composition of sleep of calming the nerves, help the most according to claim 3, it is characterised in that step (2)
In the fine powder that step (1) obtains, add 65 parts of vinegars, use slow fire fried dry, obtain Chinese medicine composition.
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| CN201610679789.7A CN106074765A (en) | 2016-08-18 | 2016-08-18 | A kind of Chinese medicine composition of sleep of calming the nerves, help |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582885A (en) * | 2017-09-21 | 2018-01-16 | 苏州仁益生物科技有限公司 | Pharmaceutical composition that a kind of soothing nerves and assisting sleep is slept and preparation method thereof |
| CN114946976A (en) * | 2022-05-12 | 2022-08-30 | 周永全 | Nerve-soothing and sleep-aiding tea and preparation method and application thereof |
-
2016
- 2016-08-18 CN CN201610679789.7A patent/CN106074765A/en not_active Withdrawn
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107582885A (en) * | 2017-09-21 | 2018-01-16 | 苏州仁益生物科技有限公司 | Pharmaceutical composition that a kind of soothing nerves and assisting sleep is slept and preparation method thereof |
| CN114946976A (en) * | 2022-05-12 | 2022-08-30 | 周永全 | Nerve-soothing and sleep-aiding tea and preparation method and application thereof |
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Application publication date: 20161109 |
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