CN104878477B - Method for preparing antibacterial alginate fibers through natural antibacterial agent - Google Patents

Abstract

The invention discloses a method for preparing antibacterial alginate fibers with different functions through a natural antibacterial agent, and belongs to the technical field of functional transformation of alginate fibers. The method comprises the following steps: dissolving a certain amount of natural antibacterial agent in ethyl alcohol to prepare a natural antibacterial agent solution with certain concentration; soaking alginate fibers in the natural antibacterial agent solution to prepare antibacterial alginate fibers which are free of doubling and disperse naturally; adding distilled water into the natural antibacterial solution while controlling the ratio of the distilled water to ethyl alcohol in the natural antibacterial agent solution, adding a certain amount of sodium alginate powder, heating, stirring to dissolve, and standing for defoaming to prepare a spinning solution containing the natural antibacterial agent; and finally, carrying out coagulating bath, drafting and the like on the spinning solution by adopting a wet spinning method to prepare the antibacterial alginate fibers with continuous antibacterial effect. The natural antibacterial agent is multifunctional and has the effects of solving the doubling problem of the alginate fibers and enhancing the antibacterial effect of the alginate fibers.

Description

A kind of method for preparing antibacterial seaweed fiber by natural antibacterial agent

technical field

The invention belongs to the technical field of functional transformation of seaweed fibers, and in particular relates to a method for preparing different antibacterial seaweed fibers from natural antibacterial agents.

Background technique

Medical dressings play the role of hemostasis, analgesia, anti-inflammation, and promotion of wound healing. The medical dressing made of calcium alginate fiber can conduct ion exchange with wound exudate and blood, accelerate the formation of blood clots and promote hemostasis. The seaweed fiber dressing will form a thin gel layer on the wound surface, thereby preventing the dressing from sticking to the wound and reducing the pain of the patient. At the same time, it can maintain a certain humidity and temperature on the wound surface, creating a good microcirculation environment for wound healing and promoting wound healing. Early healing.

Since seaweed fibers are prone to parallel filaments during the production process, the subsequent production and processing of seaweed fibers is seriously affected, and the cost and difficulty of medical dressings are increased. At the same time, the antibacterial effect of seaweed fiber itself is limited. As a raw material for medical dressings, the antibacterial effect is a very important indicator.

Contents of the invention

The purpose of the present invention is to solve the problems of the above-mentioned seaweed fibers with parallel filaments and poor antibacterial effect. The present invention prepares antibacterial seaweed fibers by adding natural antibacterial agents to the finished seaweed fibers or in the preparation process of seaweed fibers. It not only solves the problem of thread doubling, but also enhances the antibacterial effect.

One of tasks of the present invention is to provide a kind of preparation method of antibacterial seaweed fiber, comprises the following steps successively:

a, a certain amount of plant essential oil is dissolved in ethanol to prepare a certain concentration of plant essential oil solution;

b. Add distilled water to the plant essential oil solution, and control the ratio of ethanol in the distilled water to the plant essential oil solution, then add a certain amount of sodium alginate powder to it, heat and stir to dissolve, let stand for degassing, and obtain Spinning solution containing plant essential oil;

c. The spinning solution obtained in step b is wet-spun, and the antibacterial seaweed fiber is obtained after coagulation bath, drafting, shaping, dehydration and drying.

As a preferred solution of the present invention, in step a, the mass volume ratio of plant essential oil to ethanol is 0.01-0.1:1, and the plant essential oil solution is obtained by ultrasonic dispersion.

As another preferred version of the present invention, in step b, the volume ratio of distilled water to ethanol in the plant essential oil solution is 1:1.

In step b, the mass percentage of sodium alginate in the obtained spinning solution is 1-10%.

In step c, in the wet spinning method, the spinning temperature is 10-50°C, the coagulation bath is a calcium chloride solution with a mass percentage concentration of 1%-15%, the coagulation bath temperature is 30-60°C, and the draft ratio 120-300%.

Two of task of the present invention is to provide another kind of preparation method of antibacterial seaweed fiber, and it comprises the following steps:

1) Dissolving a certain amount of plant essential oil in ethanol to prepare a certain concentration of plant essential oil solution, the mass volume ratio of the plant essential oil to ethanol is 0.01-0.1:1;

2) Immerse the finished seaweed fiber tow in the plant essential oil solution obtained in step d, take it out after completely submerged for 10-30 minutes, and dry to obtain the antibacterial seaweed fiber.

In the above step e, it is better to impregnate the finished seaweed fiber tow into the natural dispersed antibacterial seaweed fiber without parallel filaments in the plant essential oil solution.

The bacteriostatic rate of the above-mentioned antibacterial seaweed fiber to Staphylococcus aureus and Escherichia coli is more than or equal to 90%.

Beneficial technical effects brought by the present invention:

The natural antibacterial agent selected in the present invention, that is, the plant essential oil solution has multifunctionality, which can not only solve the problem of parallel filaments of seaweed fibers, but also enhance the antibacterial effect of seaweed fibers

Natural antibacterial agents can be used in different preparation methods to prepare antibacterial seaweed fibers. At the same time, they can also be mixed into spinning solutions for wet spinning to prepare continuous antibacterial seaweed fibers. The medical seaweed fiber prepared by natural antibacterial agents reduces the cost of making medical dressings and the difficulty of subsequent processing, and at the same time enhances the antibacterial effect and expands the medical range of seaweed fibers.

The method of the invention can not only solve the problem of thread doubling in production, but also enhance the antibacterial effect of the seaweed fiber, make full use of the natural antibacterial agent, and at the same time make up for the shortcoming that the traditional method cannot sustain antibacterial.

The antibacterial seaweed fiber prepared by the natural antibacterial agent of the present invention can last for 5-10 days of antibacterial.

detailed description

The invention discloses a method for preparing antibacterial seaweed fiber from a natural antibacterial agent. In order to make the advantages and technical solutions of the invention clearer and clearer, the invention will be further described in conjunction with specific examples below.

The raw materials selected in the present invention, the natural antibacterial agent is selected from plant essential oils extracted from plants, which are extracted from the flowers, leaves, roots, bark, fruits, seeds, resins, etc. of herbaceous plants by distillation and pressing. Essential oils contain antibacterial and antiseptic ingredients.

Example 1:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1. Add 0.1g natural antibacterial agent (such as lavender essential oil) into 100ml ethanol solvent and mix well to make natural antibacterial agent solution;

Step 2. Weigh 30ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 1.3g of sodium alginate powder to the colloidal solution, and stir for 1 hour at 30°C to obtain a sodium alginate with a mass percentage of 1% spinning solution containing natural antibacterial agents;

Step 3, the spinning solution prepared in step 2 is left to stand, filtered, defoamed, and passed through the wet spinning method, the spinning temperature is 10 ° C, the coagulation bath is a calcium chloride solution with a mass percentage of 1%, and the coagulation bath The temperature is 30 ℃, and the antibacterial seaweed primary fiber is prepared in the coagulation bath;

Step 4, stretching, shaping, dehydrating, and drying the antibacterial seaweed nascent fiber to obtain nano zinc oxide seaweed fiber, wherein the drafting ratio is 120%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 2 days.

Example 2:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1, join 1.0g natural antibacterial agent (such as clove essential oil) in 100ml ethanol solvent and mix uniformly, make natural antibacterial agent solution;

Step 2. Weigh 20ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 6.0g of sodium alginate powder to the colloidal solution, and stir for 2 hours at 30°C to obtain a sodium alginate with a mass percentage of 5% spinning solution containing natural antibacterial agents;

Step 3, the spinning solution that step 2 is made stands, filters, defoaming, by wet spinning, and spinning temperature is 20 ℃, and coagulation bath is the calcium chloride solution that mass percent is 5%, and coagulation bath temperature Prepare antibacterial seaweed primary fibers in a coagulation bath at 30°C; stretch, shape, dehydrate, and dry the primary antibacterial seaweed fibers to obtain nano-zinc oxide seaweed fibers, wherein the draft ratio is 150%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 3 days.

Example 3:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1. Add 5.0g natural antibacterial agent (such as tea tree essential oil) into 100ml ethanol solvent and mix evenly to make natural antibacterial agent solution;

Step 2. Weigh 10ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 5.5g of sodium alginate powder to the colloidal solution, and stir for 2 hours at 40°C to obtain a sodium alginate with a mass percentage of 5 % spinning solution containing natural antibacterial agents;

Step 3, the spinning solution that step 2 is made stands, filters, defoaming, by wet spinning, spinning temperature is 30 ℃, and coagulation bath is the calcium chloride solution that mass percent is 10%, coagulation bath temperature Antibacterial seaweed primary fibers were prepared in a coagulation bath at 40°C; the antibacterial seaweed primary fibers were stretched, shaped, dehydrated, and dried to obtain nano-zinc oxide seaweed fibers, wherein the draft ratio was 200%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 5 days.

Example 4:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1, join 8.0g natural antibacterial agent (such as chrysanthemum essential oil) in 100ml ethanol solvent and mix uniformly, make natural antibacterial agent solution;

Step 2. Weigh 5ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 8.4g of sodium alginate powder to the colloidal solution, and stir for 3 hours at 50°C to obtain a sodium alginate with a mass percentage of 8 % spinning solution containing natural antibacterial agents;

Step 3, the spinning solution that step 2 is made is left standstill, filters, defoaming, by wet spinning, and spinning temperature is 40 ℃, and coagulation bath is the calcium chloride solution that mass percentage is 15%, and coagulation bath temperature Antibacterial seaweed primary fibers were prepared in a coagulation bath at 50°C; the antibacterial seaweed primary fibers were stretched, shaped, dehydrated, and dried to obtain nano-zinc oxide seaweed fibers, wherein the draft ratio was 300%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 7 days.

Example 5:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1, 10.0g natural antibacterial agent (such as Eucalyptus eucalyptus essential oil) is added in 100ml ethanol solvent and mix uniformly, make natural antibacterial agent solution;

Step 2. Weigh 1ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 10.1g of sodium alginate powder to the colloidal solution, and stir for 2 hours at 50°C to obtain a sodium alginate with a mass percentage of 10 % spinning solution containing natural antibacterial agents;

Step 3, the spinning solution prepared in step 2 is left standing, filtered, defoamed, and wet spinning, the spinning temperature is 50 ° C, the coagulation bath is a calcium chloride solution with a mass percentage of 10%, and the coagulation bath temperature Antibacterial seaweed primary fibers were prepared in a coagulation bath at 50°C; the antibacterial seaweed primary fibers were stretched, shaped, dehydrated, and dried to obtain nano-zinc oxide seaweed fibers, wherein the draft ratio was 300%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 10 days.

Embodiment 6:

The present invention, a kind of method that natural antibacterial agent prepares seaweed fiber, it specifically comprises the following steps:

Step 1, 12.0g natural antibacterial agent (such as black cumin seed oil) is added in 100ml ethanol solvent and mix uniformly, make natural antibacterial agent solution;

Step 2. Weigh 1ml of natural antibacterial agent solution and add it to 100ml of distilled water to obtain a colloidal solution, then add 10.1g of sodium alginate powder to the colloidal solution, and stir for 2 hours at 30°C to obtain a sodium alginate with a mass percentage of 10 % spinning solution containing natural antibacterial agents;

Step 3, the spinning solution prepared in step 2 is left standing, filtered, defoamed, and wet spinning, the spinning temperature is 50 ° C, the coagulation bath is a calcium chloride solution with a mass percentage of 10%, and the coagulation bath temperature Antibacterial seaweed primary fibers were prepared in a coagulation bath at 50°C; the antibacterial seaweed primary fibers were stretched, shaped, dehydrated, and dried to obtain nano-zinc oxide seaweed fibers, wherein the draft ratio was 300%.

The nano-zinc oxide seaweed fiber prepared in this example was used for antibacterial experiments, and the antibacterial effect lasted for 11 days.

It should be understood that the above-mentioned descriptions for the preferred embodiments are relatively detailed, and should not therefore be considered as limiting the scope of the patent protection of the present invention. Within the scope of protection, various modifications such as replacement and simple combination can also be made, and the protection scope of the present invention should be based on the appended claims.

Claims (2)

1. a kind of preparation method of antibacterial alginate fibre it is characterised in that：Comprise the following steps successively：

A, plants essential oil is dissolved in ethanol, certain density plants essential oil solution is obtained by the way of ultrasonic disperse, described Plants essential oil is 0.01-0.1 with the mass volume ratio of ethanol:1；

B, add distilled water in described plants essential oil solution, and control the body of ethanol in described distilled water and plants essential oil solution Long-pending ratio is 1:1, then it is added thereto to a certain amount of sodium alginate powder, heating stirring and dissolving, standing and defoaming, be obtained containing plant The spinning solution of thing quintessence oil, in gained spinning solution, the mass percent of sodium alginate is 1-10%；

C, step b gained spinning solution is adopted wet spinning process, through coagulating bath, drawing-off, sizing, dehydration, be dried after be obtained Antibacterial alginate fibre.

2. antibacterial alginate fibre according to claim 1 preparation method it is characterised in that：In step c, wet spinning process In, spinning temperature is 10-50 DEG C, and the calcium chloride solution that mass percent concentration is 1%-15% is selected in coagulating bath, solidifies bath temperature Spend for 30-60 DEG C, draw ratio is 120-300%.