CN104770361A - Supplied-liver quickly-fixed perfusion device for liver transplant - Google Patents

Abstract

The invention relates to the field of medicine, in particular to the accurate and rapid connection and perfusion of a perfusion device for obtaining a donor liver during organ transplantation (liver), in particular to a rapid fixed perfusion device for a liver during liver transplantation. The fast fixation and perfusion device for liver donor in liver transplantation includes a puncture guide device and a connecting ring connected to the perfusion tube, the puncture guide device is a puncture steel wire with a retractable ring at the top, and the retractable ring is magnetic; The top of the connecting ring is tapered, the bottom of the connecting ring is connected to the perfusion pipe, the bottom of the connecting ring is provided with a unidirectional flow valve, the top of the connecting ring is made of iron-containing material, and the top of the connecting ring is compatible with the shrinkable ring. and are magnetically attracted to each other. The operation of the invention is simple and feasible, and has strong pertinence, and is mainly used for rapid perfusion when the donor liver is obtained during liver transplantation. The invention provides an effective technical guarantee for fast and efficient liver perfusion and obtaining high-quality donor livers.

Description

Donor Liver Rapid Fixed Perfusion Device in Liver Transplantation

technical field

The invention relates to the field of medicine, in particular to the accurate and rapid connection and perfusion of a perfusion device for obtaining a donor liver during organ transplantation (liver), in particular to a rapid fixed perfusion device for a liver during liver transplantation.

Background technique

At present, liver transplantation has become a routine treatment for end-stage liver disease. This year, with the continuous promotion and improvement of liver transplantation technology in my country, the survival rate after liver transplantation has been continuously improving. The incidence of postoperative complications is also decreasing year by year. In liver transplantation, one of the key techniques in obtaining the donor liver is perfusion of the liver in situ. How to accurately locate and quickly perform catheter fixation and perfusion is a technical problem in obtaining high-quality liver sources.

When obtaining a traditional liver donor, the liver is quickly explored after laparotomy to find out whether there is cirrhosis, liver space occupying and severe fatty liver. For the artery, cut the anterior wall above its bifurcation, insert a modified Foley catheter with 2 to 3 side holes proximally, insert the catheter to the depth above the level of the opening of the abdominal aorta from the balloon, and inject 25ml of normal saline into the balloon , perfuse with lavage fluid at 0-4°C. After completion of abdominal aortic cannulation, portal perfusion was initiated. The assistant pulls the duodenum downward, and the operator splits the head of the pancreas to find the root of the superior mesenteric vein behind the pancreas, cuts its front wall, and inserts a self-made portal vein cannula with a depth of 2-3 cm to prevent insertion Go too deep into the portal vein branch and ligate the splenic vein. After the garza is fixed, start the perfusion. This operation requires the surgeon to be proficient in accurately positioning the depth of the cannula, and quickly fix the cannula with the assistance of an assistant. However, in this process, the intubation is prone to be too deep. At this time, the perfusate flows to the right hemihepatic roof, which may easily lead to insufficient perfusion of the left and right livers. The cooling rate in the middle is slower, resulting in differences in the ischemic time between the left and right livers. In addition, in the process of cannula fixation, traditional thread ligation also affects the installation time of the overall perfusion device depending on the operator's proficiency. At the same time, there is no device to prevent liquid reflux in the traditional perfusion pipeline, and the liquid perfusion completely relies on gravity to enter the donor liver. During the entire perfusion process, various factors may cause the perfusate to reflux at any time, resulting in a slowdown of the perfusion speed. Therefore, looking for an auxiliary device for fast positioning and installation of the perfusion device can facilitate the operation of the operator, ensure the quality of the donor liver on the basis of greatly reducing the time for perfusion intubation, and improve the prognosis and quality of life of liver transplant patients. greater significance.

Contents of the invention

The present invention creatively proposes an auxiliary device for rapid fixation and perfusion in liver transplantation. The device is simple and feasible to operate, and has strong pertinence. It can shorten the installation time of the perfusion device and quickly complete liver perfusion, preventing the reflux of perfusate. .

The fast fixation and perfusion device for liver donor in liver transplantation includes a puncture guide device and a connecting ring connected to the perfusion tube, the puncture guide device is a puncture steel wire with a retractable ring at the top, and the retractable ring is magnetic; The top of the connecting ring is tapered, the bottom of the connecting ring is connected to the perfusion pipe, and a unidirectional flow valve is provided inside the bottom of the connecting ring, the top of the connecting ring is made of iron-containing material, and the top of the connecting ring is compatible with the shrinkable ring. and are magnetically attracted to each other.

Preferably, the conical surface at the top of the connecting ring is provided with sieve-shaped holes.

Preferably, a catheter is provided outside the puncture steel wire.

Preferably, the retractable ring at the top of the puncture guiding device is controlled by a puncture wire to expand.

Preferably, the length of the puncture steel wire is 30 cm.

Preferably, the connecting ring has an inner diameter of 0.8 cm and a height of 2 cm.

Preferably, the puncture steel wire is a composite biological material composed of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene, etc.; the tapered part at the top of the connecting ring is a biologically stable composite biological material composed of iron-containing substances, It can be magnetically linked with the retractable ring at the top of the puncture needle; the rest of the structure is ABS plastic.

The present invention is further elaborated below:

The donor liver rapid fixation and perfusion device in liver transplantation consists of two parts, including a liver puncture guide device with a hidden magnetic retractable expansion ring at the head end and a matching circular connecting ring with a valve-shaped head end.

1) Liver puncture guiding device with hidden magnetic retractable expansion ring at the head end: its shape is generally a long and thin liver puncture steel wire with a slightly soft texture, the length is 30 cm, and its material is made of stainless steel, nickel/platinum, polyurethane, polyester, etc. Composite biomaterials composed of tetrafluoroethylene, etc., mainly play the role of puncture and guide into the portal vein; its head end has a retractable ring-shaped device, and its material is ferrite magnetic material with good comprehensive performance and stable chemical performance. It can be stretched after operation from the tail end (the inner diameter is 0.8 cm), and it can expand blood vessels.

2) Connecting ring: it matches with the liver puncture guide device. The head end of the connecting ring is tapered, and the material is iron-containing material, which matches the liver puncture expansion ring. The two form a magnetic adsorption fast anastomosis device, which plays the role of fixing the expansion ring. The tapered end is sharp and can quickly puncture blood vessels. The wall plays the role of opening up blood vessels. Its surface is designed with sieve holes to facilitate the rapid flow of perfusate into the liver; the inside of the connecting ring is designed with a one-way valve, so that perfusion can only flow into the liver through the outside and cannot flow backward; the tail end is The perfusion tube connection port is used to connect the perfusion pipeline. The tapered part at the top of the connecting ring is a composite biological material with stable biological properties composed of iron-containing substances, which can be magnetically linked with the shrinkable ring at the top of the puncture needle; the remaining structure is ABS plastic (acrylonitrile) with good comprehensive performance and stable chemical properties. -butadiene-styrene), with an inner diameter of 0.8 cm and a height of 2 cm.

Compared with the traditional method of obtaining perfusion from donated liver, the present invention has obvious beneficial effects:

(1) Quickly locate the dilated blood vessels. After laparotomy and liver exploration, the liver puncture guide can quickly reach the lower end of the portal vein and connect the pipeline.

(2) Make full use of the characteristics of the magnetic material to connect the connecting ring and the guiding device, quickly puncture the blood vessel for blood perfusion, and avoid the artificial difference of the operator who traditionally uses the thread ligation.

(3) With the design of valve perfusion model, the perfusion fluid can only flow in one direction, which ensures the unidirectionality in the perfusion process and improves the perfusion efficiency.

The present invention adopts the puncture steel wire, especially the length of 30 centimeters, which can avoid the situation that the intubation is too deep to cause insufficient left and right liver perfusion; Matching, the two constitute a magnetic adsorption rapid anastomosis device, which plays the role of fixing the expansion ring. Its tapered end is sharp, which can quickly pierce the blood vessel wall and play the role of opening the blood vessel. Its surface is designed with sieve holes, which is convenient for perfusion. Quickly flow into the liver; the inside of the connecting ring is designed with a one-way valve, so that the perfusion can only flow into the liver through the outside and cannot be reversed; the end of the perfusion tube is the connection port for connecting the perfusion tube. The operation of the invention is simple and feasible, and has strong pertinence, and is mainly used for rapid perfusion when the donor liver is obtained during liver transplantation. The invention obviously shortens the installation time of the perfusion device, and provides effective technical support for fast and efficient liver perfusion and obtaining high-quality donor livers.

Description of drawings

Fig. 1 is a schematic structural view of the puncture guiding device of Embodiment 1.

Fig. 2 is a schematic diagram of the changing process of the shrinkable ring at the top of the puncture guiding device in Embodiment 1.

FIG. 3 is a schematic structural view of the connecting ring in Embodiment 1.

Fig. 4 is a schematic diagram of the structure of the one-way valve inside the connecting ring.

Fig. 5 is a schematic diagram of the combination of the puncture guide device and the connecting ring in the first embodiment for liver transplantation.

Detailed ways

The present invention will be further described below in conjunction with specific examples. It should be understood that the following examples are only used to illustrate the present invention and are not intended to limit the protection scope of the present invention.

The methods used in the following examples are conventional methods unless otherwise specified. The materials or reagents required in the following examples are commercially available unless otherwise specified.

Example 1

Figures 1-2 and Figures 3-4 respectively show the liver puncture guide device with the magnetic retractable expansion ring hidden at the head end and the matching circular connecting ring. As shown in Figure 1-2, the liver puncture guide device is composed of a guide wire 2 and a catheter 1, and its material is a composite biological material composed of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene, etc., which is soft and plastic. It mainly plays the role of puncture guide into the portal vein. The leading end of the guide wire 2 has a shrinkable ring 2-1, and the shrinkable ring 2-1 is connected by a special process by discontinuous segments to facilitate shrinkage and relaxation. Its material is iron oxide with good comprehensive performance and stable chemical properties. The body magnetic material can be stretched after being manipulated by the tail end of the guide wire 2 (the inner diameter of which is 0.8 cm after being stretched), so as to play the role of dilating blood vessels.

As shown in Figure 3-4, it is a circular connecting ring 3 with a tapered head end and a valve-type design inside. diene-styrene), with an inner diameter of 0.8 cm and a height of 2 cm. Its head end is a conical structure, and the conical surface is a sieve-shaped design. The material is made of iron-containing material, which can be connected with the expanded retractable ring 2-1 at the top of the liver puncture guide device by magnetic means after penetrating the blood vessel. Secure the retractable ring 2-1. The sharp tapered tip design can quickly penetrate blood vessels to form a perfusion channel. The tail end is the connection port of the perfusion tube, which is used to connect the perfusion tube; there is a one-way valve inside the connecting ring 3 (Figure 4), so that the perfusion liquid can only flow into the liver through the outside and cannot flow backward, so as to achieve the effect of rapid perfusion .

Figure 5 shows the operation flow of the whole device. In the process of obtaining the liver donor, after laparotomy and rapid detection of the condition of the liver, the liver puncture guide device is used to penetrate through the surface of the liver to reach the lower end of the portal vein. The retractable ring 2-1 expands and props up the portal vein. At this time, the magnetic retractable ring 2-1 is quickly connected to the connecting ring 3 by using magnetic attraction, and the connecting ring 3 is slightly rotated so that it can be firmly fastened. The magnetic retractable ring 2-1 inside the blood vessel is connected and installed like this. Thereafter, insert and connect the tail end of the connecting ring 3 with a perfusion tube to start perfusion.

From the above description, it is not difficult to find that the present invention has obvious advantages compared with the traditional methods of obtaining perfusion of liver donors: (1) rapid positioning of dilated blood vessels, and can quickly reach the portal vein through liver puncture guidance after laparotomy. Lower end and pipe connections. (2) Make full use of the characteristics of the magnetic material to connect the tube, and the tapered head quickly punctures the blood vessel for blood perfusion, avoiding the artificial difference of the operator who traditionally uses the thread ligation. (3) With the design of valve perfusion model, the perfusion fluid can only flow in one direction, which ensures the unidirectionality of liquid flow in the perfusion process and improves the perfusion efficiency. The invention obviously shortens the installation time of the perfusion device, and provides effective technical support for fast and efficient liver perfusion and obtaining high-quality donor livers.

Finally, it should also be noted that the above examples are only specific implementation examples of the present invention. Apparently, the present invention is not limited to the above examples, and many variations are possible. All deformations that can be directly derived or associated by those skilled in the art from the content disclosed in the present invention should be considered as the protection scope of the present invention.

Claims (7)

1. The device for quickly fixing and perfusing the donor liver during liver transplantation, characterized in that it includes a puncture guide device and a connecting ring connected to the perfusion tube, the puncture guide device is a puncture steel wire with a retractable ring at the top, and the retractable ring With magnetism; the top of the connecting ring is conical, the bottom of the connecting ring is connected to the perfusion tube, and the bottom of the connecting ring is provided with a unidirectional flow valve, the top of the connecting ring is made of ferrous material, and the top of the connecting ring is connected to the The shrink rings fit together and attach to each other magnetically. 2. The device for rapid fixation and perfusion of a liver donor during liver transplantation according to claim 1, characterized in that: the conical surface at the top of the connecting ring is provided with a sieve-shaped hole. 3 . The device for rapid fixation and perfusion of the donor liver during liver transplantation according to claim 1 , wherein a catheter is provided outside the puncture wire. 4 . 4 . The device for rapid fixation and perfusion of a liver donor during liver transplantation according to claim 1 , wherein the retractable ring at the top of the puncture guiding device is controlled to open by a puncture wire. 5 . The device for rapid fixation and perfusion of the donor liver during liver transplantation according to claim 1 , wherein the length of the puncture steel wire is 30 cm. 6 . The device for quickly fixing and perfusing a donor liver during liver transplantation according to claim 1 , wherein the connecting ring has an inner diameter of 0.8 cm and a height of 2 cm. 7 . 7. The device for quickly fixing and perfusing a donor liver during liver transplantation according to claim 1, characterized in that: the puncture steel wire is made of composite biomaterials composed of stainless steel, nickel/platinum, polyurethane, polytetrafluoroethylene, etc.; The conical part at the top of the connection ring is composed of a biologically stable composite biomaterial composed of iron-containing substances, which can be magnetically linked with the retractable ring at the top of the puncture needle; the rest of the structure is ABS plastic.