CN104630009A - Liver protecting liquor resisting alcoholic liver damage and preparation method thereof - Google Patents
Liver protecting liquor resisting alcoholic liver damage and preparation method thereof Download PDFInfo
- Publication number
- CN104630009A CN104630009A CN201510086520.3A CN201510086520A CN104630009A CN 104630009 A CN104630009 A CN 104630009A CN 201510086520 A CN201510086520 A CN 201510086520A CN 104630009 A CN104630009 A CN 104630009A
- Authority
- CN
- China
- Prior art keywords
- liver
- liquor
- protecting
- alcohol tolerance
- white spirit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 210000004185 liver Anatomy 0.000 title abstract description 11
- 208000022309 Alcoholic Liver disease Diseases 0.000 title abstract 5
- 206010067125 Liver injury Diseases 0.000 claims abstract description 32
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 21
- 239000000654 additive Substances 0.000 claims abstract description 17
- 235000014101 wine Nutrition 0.000 claims abstract description 17
- 244000241838 Lycium barbarum Species 0.000 claims abstract description 16
- 235000015459 Lycium barbarum Nutrition 0.000 claims abstract description 16
- 235000015468 Lycium chinense Nutrition 0.000 claims abstract description 16
- 230000000996 additive effect Effects 0.000 claims abstract description 16
- 244000189799 Asimina triloba Species 0.000 claims abstract description 12
- 235000006264 Asimina triloba Nutrition 0.000 claims abstract description 12
- 235000009467 Carica papaya Nutrition 0.000 claims abstract description 12
- 244000046146 Pueraria lobata Species 0.000 claims abstract description 11
- 235000010575 Pueraria lobata Nutrition 0.000 claims abstract description 11
- 239000002994 raw material Substances 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 33
- 231100000753 hepatic injury Toxicity 0.000 claims description 31
- 235000020097 white wine Nutrition 0.000 claims description 28
- 235000009917 Crataegus X brevipes Nutrition 0.000 claims description 9
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 claims description 9
- 235000009685 Crataegus X maligna Nutrition 0.000 claims description 9
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 claims description 9
- 235000009486 Crataegus bullatus Nutrition 0.000 claims description 9
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 claims description 9
- 235000009682 Crataegus limnophila Nutrition 0.000 claims description 9
- 235000004423 Crataegus monogyna Nutrition 0.000 claims description 9
- 240000000171 Crataegus monogyna Species 0.000 claims description 9
- 235000002313 Crataegus paludosa Nutrition 0.000 claims description 9
- 235000009840 Crataegus x incaedua Nutrition 0.000 claims description 9
- 229920001525 carrageenan Polymers 0.000 claims description 9
- 235000010418 carrageenan Nutrition 0.000 claims description 9
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims description 9
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims description 8
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims description 8
- 229960002675 xylitol Drugs 0.000 claims description 8
- 235000010447 xylitol Nutrition 0.000 claims description 8
- 239000000811 xylitol Substances 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 6
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 4
- 229910052799 carbon Inorganic materials 0.000 claims description 4
- 125000003118 aryl group Chemical group 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 13
- 239000000463 material Substances 0.000 abstract description 6
- 230000009471 action Effects 0.000 abstract description 3
- 239000003205 fragrance Substances 0.000 abstract description 2
- 235000014493 Crataegus Nutrition 0.000 abstract 1
- 241001092040 Crataegus Species 0.000 abstract 1
- 231100000234 hepatic damage Toxicity 0.000 abstract 1
- 230000008818 liver damage Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 description 17
- 150000002148 esters Chemical class 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- 239000002253 acid Substances 0.000 description 7
- 235000009508 confectionery Nutrition 0.000 description 7
- 210000003205 muscle Anatomy 0.000 description 6
- -1 polysaccharide compound Chemical class 0.000 description 6
- 230000008569 process Effects 0.000 description 6
- 239000008280 blood Substances 0.000 description 5
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 230000007423 decrease Effects 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 4
- 235000019634 flavors Nutrition 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- 206010010904 Convulsion Diseases 0.000 description 3
- 230000036461 convulsion Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 229920001282 polysaccharide Polymers 0.000 description 3
- 239000005017 polysaccharide Substances 0.000 description 3
- 210000000952 spleen Anatomy 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 239000002023 wood Substances 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 241000244355 Ligusticum Species 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 244000309466 calf Species 0.000 description 2
- 235000013339 cereals Nutrition 0.000 description 2
- 239000002131 composite material Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 230000000050 nutritive effect Effects 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 230000035922 thirst Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 241000283725 Bos Species 0.000 description 1
- 240000000425 Chaenomeles speciosa Species 0.000 description 1
- 206010008631 Cholera Diseases 0.000 description 1
- 244000037364 Cinnamomum aromaticum Species 0.000 description 1
- 235000014489 Cinnamomum aromaticum Nutrition 0.000 description 1
- 235000000314 Crataegus calpodendron Nutrition 0.000 description 1
- 241001019596 Crataegus calpodendron Species 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241001465251 Ephedra sinica Species 0.000 description 1
- 241001428166 Eucheuma Species 0.000 description 1
- 240000006859 Jasminum officinale Species 0.000 description 1
- 235000010254 Jasminum officinale Nutrition 0.000 description 1
- 241000366676 Justicia pectoralis Species 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
- 201000005505 Measles Diseases 0.000 description 1
- 208000001140 Night Blindness Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 235000019082 Osmanthus Nutrition 0.000 description 1
- 241000333181 Osmanthus Species 0.000 description 1
- 235000004347 Perilla Nutrition 0.000 description 1
- 244000124853 Perilla frutescens Species 0.000 description 1
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 208000000491 Tendinopathy Diseases 0.000 description 1
- 208000023835 Tendon disease Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 206010047601 Vitamin B1 deficiency Diseases 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 231100000403 acute toxicity Toxicity 0.000 description 1
- 230000007059 acute toxicity Effects 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 235000020051 akvavit Nutrition 0.000 description 1
- 230000001476 alcoholic effect Effects 0.000 description 1
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000000259 anti-tumor effect Effects 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 235000006708 antioxidants Nutrition 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 208000002894 beriberi Diseases 0.000 description 1
- 235000013734 beta-carotene Nutrition 0.000 description 1
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 1
- 239000011648 beta-carotene Substances 0.000 description 1
- 229960002747 betacarotene Drugs 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 150000001746 carotenes Chemical class 0.000 description 1
- 235000005473 carotenes Nutrition 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010931 ester hydrolysis Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 230000004345 fruit ripening Effects 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 229960004232 linoleic acid Drugs 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 235000009458 pearthorn Nutrition 0.000 description 1
- 210000003899 penis Anatomy 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000010791 quenching Methods 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 208000018556 stomach disease Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- 239000012747 synergistic agent Substances 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- NCYCYZXNIZJOKI-UHFFFAOYSA-N vitamin A aldehyde Natural products O=CC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C NCYCYZXNIZJOKI-UHFFFAOYSA-N 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000015099 wheat brans Nutrition 0.000 description 1
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12G—WINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
- C12G3/00—Preparation of other alcoholic beverages
- C12G3/04—Preparation of other alcoholic beverages by mixing, e.g. for preparation of liqueurs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/732—Chaenomeles, e.g. flowering quince
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to liver protecting liquor resisting alcoholic liver damage and a preparation method thereof. The liver protecting liquor resisting alcoholic liver damage comprises the raw materials in parts by weight as follows: 400-800 parts of liquor, 20-40 parts of kudzuvine root, 20-40 parts of hawthorns, 20-40 parts of pawpaws and 20-40 parts of wolfberry fruit. The liver protecting liquor resisting alcoholic liver damage can furthest give play to the combined action of the medicinal materials, the liquor is soft in wine body, soft-sweet, tasty and refreshing, harmonious in fragrance, fresh in taste and has the function of resisting alcoholic liver damage, the effect for reducing liver damage is obvious, the problem of poor stability of the liquor is solved especially after the additive is used.
Description
Technical field
The present invention relates to the manufacture field of white wine, be specifically related to liver-protecting white spirit of a kind of alcohol tolerance liver injury and preparation method thereof.
Background technology
White wine take Cereals as main raw material, with Daqu, little song or wheat bran and distiller's yeast etc. for saccharifying ferment, through boiling, saccharification, fermentation, distillation and the liquor made.Also known as liquor, white spirit, aquavit etc.Vinosity colourless (or micro-Huang) is transparent, and fragrant odour is pure, and entrance is sweet refreshing clean, and ethanol content is higher, through store aging after, have based on the compound fragrant of ester class.
White wine has another name called liquor, white spirit, is the traditional beverages wine of China, welcomes by Chinese very much.Record according to Compendium of Material Medica: " also, original when unit, its method heavy wine and grain enter rice steamer (referring to steamer) to liquor Fei Gufa, steam and make on gas, hold drip dew with device." can draw thus, the production of China's white wine has very long history.
White wine is the distinctive a kind of liquor of China.The wine degree of white wine, generally more than 41 degree, how more than 55 degree, is generally no more than 65 degree.Low powered posterior chamber white wine refers to and have employed degree of falling technique, and wine degree, generally at 38 degree, even reaches the white wine of degree more than 20, is called for short low alcohol.The degree of falling of wine generally adopts and adds highly purified distilled water to realize in female wine.
So-called " Chen Yuexiang got over by wine ", refers to the white wine of more than 38 degree more.These white wine only need the dated date manufactured, do not need the dated quality guaranteed period.But for low powered posterior chamber white wine, be not but " more Chen Yuexiang ".Research finds, it is all rise that the total acid in white wine is deposited in process at shelf-lives, and the amplitude of 30 ° of wine risings is larger, and 20% ~ 28%, the 38 ° of wine that rise every year on average rise 13% ~ 22% every year on average.In storage process, the major cause that acid increases is: a, white wine occur hydrolysis phenomena depositing in process, generates corresponding acid and ethanol after Ester hydrolysis.The volatility coefficient of b, acid is little, not volatile in storage process.And total ester in white wine to deposit in process at shelf-lives be all decline, the amplitude that 30 ° of wine declines is larger, and 7% ~ 13%, the 38 ° of wine that decline every year on average decline 5% ~ 9% every year on average.For low alcohol, due to CH
3cH
2oH concentration is lower, H
2o concentration is higher, and the speed of forward hydrolysis, thus hydrolysis causes total ester to deposit the major cause declined in process at shelf-lives.
Health-care spirit or medicinal liquor, generally take white wine as base wine, but the traditional Chinese medicine ingredients of some medicine-food two-purposes is added in order to possess health-care effect, in order to ensure the drug effect of traditional Chinese medicine ingredients, and facilitate quoting of specific crowd, the medicinal liquor with health-care effect on market is all 35 degree or the lower low powered posterior chamber white wine of the number of degrees usually.Therefore, health-care spirit generally has the less stable of low powered posterior chamber white wine, between staging life, and degradation shortcoming under the rising of acid amount, ester amount.
Summary of the invention
One of technical problem to be solved by this invention is to provide a kind of liver-protecting white spirit of alcohol tolerance liver injury.
Two of technical problem to be solved by this invention is to provide the preparation method of the liver-protecting white spirit of above-mentioned alcohol tolerance liver injury.
The scheme solved this technical problem is:
A liver-protecting white spirit for alcohol tolerance liver injury, comprises following weight parts raw material composition: white wine 400-800 part, root of kudzu vine 20-40 part, hawthorn 20-40 part, pawpaw 20-40 part, wolfberry fruit 20-40 part.
Preferably,
Described white wine is the white wine of wine degree 25-38 degree.
Described white wine be scent type or aromatic Chinese spirit.
The liver-protecting white spirit of described alcohol tolerance liver injury can also comprise the additive of 1-9 weight part.
Preferred further, described additive, comprises the component of following weight parts: 3-hydroxyl-2-ethyl-pyrokomane 10-30 part, Xylitol 20-40 part, carrageenin 10-20 part.
Present invention also offers the preparation method of the liver-protecting white spirit of described alcohol tolerance liver injury, it comprises the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter.
Preferably,
Step (1) described soak time is 15-30 days.
Soaking conditions is soak under normal temperature (25 ± 5 DEG C) air-proof condition.
After step (2), additive can be added by proportioning, the liver-protecting white spirit of the obtained preferred alcohol tolerance liver injury containing additive.
In the present invention,
Pawpaw, Chinese medicine name.For the dry almost ripe fruit of rosaceous plant chaenomeles lagenaria.Summer, autumn two gather when season, fruit was greenish-yellow, and put in boiling water and scald to crust canescence, double vertical profile, dries.Function: stimulate the circulation of the blood and cause the muscles and joints to relax, and effect of stomach dampness elimination.Compendium of Material Medica: the main cholera of pawpaw tells profit convulsion, beriberi, all the spleen-stomach diseases, and non-hepatic disorder also.Though the main muscle of liver, convulsion is then attacked caused by imapirment of the spleen and stomach by heresy that is damp and hot, cold-dampness, therefore myospasm must arise from sufficient calf, and it is bright that calf and penis all belong to sun.Pawpaw controls convulsion, and also, reason spleen and cut down liver also, native disease then gold declines and wood is contained non-beneficial muscle, therefore with the dissipation of sour Wen Yishou taste, and it is evil with flat liver to borrow it to walk muscle, is rush down wood in soil to help gold also.Then native must order and Jin Shouyin put down by wood." Plain Questions " cloud: sour flavor being apt to act on the tendon, being unsuitable for tendon-disease to be treated with drugs of sour flavor.The Meng numerous cloud: many food pawpaws damage tooth and bone.The bright of clear felling liver is tested, and pawpaw is started with, foot is lunar, and be taste medicine, non-liver medicine, benefit can be levied.
The root of kudzu vine, Chinese medicine name.For the dry root of legume pueraria lobata, practise and claim elegant jessamine.Autumn, season in winter two excavate, and take advantage of fresh-cut and become sheet or fritter; Dry.Sweet, pungent, cool.There is expelling pathogenic factors from muscles for reducing heat, promoting eruption, promote the production of body fluid to quench thirst, rise the merit of positive antidiarrheal.Be usually used in illness that has not attacked the vital organs of the human body heating, stiff nape and back, measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, diarrhea due to hypofunction of the spleen." book on Chinese herbal medicine converges and says ": " root of kudzu vine, fresh breeze is trembled with fear, and only shows heresy, expelling pathogenic factors from muscles and skin heat, only polydipsia.Rush down the medicine of stomach fire also.Taste the medicine that loose heresy is delivered in sight, its product are also many, pull out sun battalion divide cold as Chinese ephedra, the wind that cassia twig Xie Taiyangwei divides, windproof, purple perilla falls apart the chill of the sun at table, and Jehol Ligusticum Rhizome, notopterygium root fall apart the cold-dampness of the sun at table, all claim to disperse medicine also, and dispersing of the root of kudzu vine, also enter the sun, also dispersing wind and cold, different again, if non-numb, osmanthus, Soviet Union, anti-, pungent fragrant temperature is dry, disperse and damage middle gas mistake also; If non-Jehol Ligusticum Rhizome, notopterygium root, disperse and have consumption ying blood anxiety also.”
Hawthorn, Chinese medicine name.For the dry mature fruit of rosaceous plant Fruit of Pashi Pear or hawthorn.Gather during fruit maturation in autumn, section, dry." Records of Tradition Chinese and Western Medicine in Combination ": hawthorn, if help it with sweet medicine, Removing Blood Stasis and do not hinder new blood, open strongly fragrant gas and do not hinder healthy tendency, the outstanding peace of its property also.
Wolfberry fruit is traditional rare traditional Chinese medicine, is again a kind of nutritional supplements.In the list of 63 kinds of medicine-food two-purposes of Ministry of Health's announcement, rank first.As traditional Chinese medicine, the flat taste of wolfberry fruit is sweet, has effect of nourishing liver and kidney, replenishing vital essence to improve eyesight, moistening lung.Pass through chemical composition analysis, the fruit of wolfberry fruit detects containing nutritive ingredients such as abundant natural Beta-carotene, vitamins C, wolfberry fruit protein-polysaccharide, trimethyl-glycine, linolic acid and iron, phosphorus, calcium, has qi-restoratives to calm the nerves, improving eyesight is dispeled the wind, nourshing kidney moistening lung and protect the effects such as liver is antitumor.Wolfberry fruit contains the required nutritive substance of abundant carotene, multivitamin and the healthy eye such as calcium, iron, therefore has the merit of improving eyesight, is commonly called as " bright eye ".What ancient Chinese medicine doctor treatment deficiency of liver-blood, deficiency of kidney-YIN caused looks thing duskization and nyctalopia, usually uses wolfberry fruit.Further, wolfberry fruit is from the Book of Songs " combines in luxuriant Qi ", and just for medicine, the history in existing more than 3000 years so far, just has the alone wolfberry fruit of Jin Chaoge flood to smash juice from ancient times and drip order, the story for the treatment of ophthalmology illness.The name of wolfberry fruit, first appeared in Shennong's Herbal, is listed as top grade, very popular over the past thousands of years.
3-hydroxyl-2-ethyl-pyrokomane, No. CAS: 4940-11-8.China GB2760-86 is defined as the food and spices that allow to use, and being a kind of fragrance synergistic agent, is a kind of safety non-toxic, has flavouring, increases sweet, to protect the effects such as fragrant and covering smell foodstuff additive.
Xylitol, No. CAS: 87-99-0.
Carrageenin, No. CAS: 11114-20-8.Carrageenin is a kind of polysaccharide extracted from marine red alga (mainly various Eucheuma muricatum (Gmel.) Web. Van Bos.), and its chemical structure is the linear polysaccharide compound that D-semi-lactosi and 3,6-dehydration-D-galactose residue form, with ester formula sulfate group on residue.
The liver-protecting white spirit of alcohol tolerance liver injury of the present invention, the comprehensive action of various medicinal material can be played to greatest extent, wine body is soft, sweet tasty and refreshing, all fragrant harmonies, taste is refreshing clean, there is the effect of alcohol tolerance liver injury, to the Be very effective reducing liver injury, after especially employing additive, solve the problem of low powered posterior chamber white wine poor stability.In prior art, white wine does not normally add additive, but due to medicinal liquor or the health-care spirit number of degrees lower, along with the time can generating portion acidifying, acid number rises, ester amount declines, Xylitol in additive can react with acid, generates the ester with aromatising flavour with its reaction, and carrageenin is as a kind of dispersion agent, the liver-protecting white spirit of antagonism alcoholic liver injury serves stable effect, and 3-hydroxyl-2-ethyl-pyrokomane can remove the peculiar smell of the Chinese medicinal materials in health-care spirit.Unexpectedly, research finds: when to use 3-hydroxyl-2-ethyl-pyrokomane, Xylitol and carrageenin simultaneously, the decline slowing down ester amount in health-care spirit is served to the effect of synergy.The liver-protecting white spirit preparation method of alcohol tolerance liver injury of the present invention is simple, easy preservation.
Embodiment
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Get 35 degree of white wine 600 kilograms, put into pawpaw 30 kilograms, the root of kudzu vine 30 kilograms, hawthorn 30 kilograms, wolfberry fruit 30 kilograms, sealing, soak at room temperature 30 days, remove peculiar smell and muddiness with active carbon for liquor SB-204, filter, obtain the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 1.
Show through acute toxicity test result, acute toxicity is extremely low, and security is high; Pharmacodynamic experiment result shows, has the effect of alcohol tolerance liver injury, from pathological section and Antioxidant index, to the Be very effective reducing liver injury.
The liver-protecting white spirit of alcohol tolerance liver injury of the present invention, can play the comprehensive action of various medicinal material to greatest extent, wine body is soft, sweet tasty and refreshing, all fragrant harmonies, and taste is refreshing clean, has the effect of alcohol tolerance liver injury, to the Be very effective reducing liver injury.
Embodiment 2-5
Take each raw material according to the additive formulations of embodiment 2-5 in table 2, mix, obtained additive.Take 3 grams of additives to join in the liver-protecting white spirit of the obtained alcohol tolerance liver injury of 720 grams of embodiments 1, be uniformly mixed, make the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 2-5.
Table 1: additive formulations table (unit: kilogram)
3-hydroxyl-2-ethyl-pyrokomane | Xylitol | Carrageenin | |
Embodiment 2 | 20 | 30 | 15 |
Embodiment 3 | / | 30 | 35 |
Embodiment 4 | 20 | 45 | / |
Embodiment 5 | 20 | / | 45 |
Test case
Detect lucifuge normal temperature sealed type storage after 20 months, the content of main ester compound in the health-care spirit of embodiment 1-5, test result is in table 2.
Table 2: embodiment 1-5 health-care spirit ester compound is containing scale (unit: g/L)
Ethyl acetate | Ethyl lactate | Ethyl butyrate | Ethyl hexanoate | |
Just prepared embodiment 1 | 0.6020 | 0.7885 | 0.0185 | 0.0232 |
Embodiment 1 after 20 months | 0.3788 | 0.4211 | 0.0084 | 0.0126 |
Embodiment 2 after 20 months | 0.4652 | 0.5921 | 0.0155 | 0.0186 |
Embodiment 3 after 20 months | 0.4173 | 0.4956 | 0.0122 | 0.0142 |
Embodiment 4 after 20 months | 0.4384 | 0.5102 | 0.0133 | 0.0145 |
Embodiment 5 after 20 months | 0.4091 | 0.4825 | 0.0124 | 0.0137 |
From experimental result, store after 20 months, in the liver-protecting white spirit of the alcohol tolerance liver injury of embodiment 1-5, several main ester compound content has maintained higher level, maintains good aromatising flavour and mouthfeel, especially, after embodiment 2-4 employs additive, ester class content is higher.
More particularly, embodiment 2 employs Xylitol, carrageenin, 3-hydroxyl-2-ethyl-pyrokomane three are composite, compared with embodiment 3-5 adopt respectively in Xylitol, carrageenin and 3-hydroxyl-2-ethyl-pyrokomane any two kinds composite, lucifuge normal temperature sealed type storage after 20 months ester compound content maintain higher level, three's synergy, effect is more obvious.
Claims (8)
1. a liver-protecting white spirit for alcohol tolerance liver injury, is characterized in that, comprises following weight parts raw material composition: white wine 400-800 part, root of kudzu vine 20-40 part, hawthorn 20-40 part, pawpaw 20-40 part, wolfberry fruit 20-40 part.
2. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 1, is characterized in that: the wine degree of the liver-protecting white spirit of described alcohol tolerance liver injury is 25-38 degree.
3. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 1, is characterized in that: the liver-protecting white spirit of described alcohol tolerance liver injury be scent type or aromatic Chinese spirit.
4. the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 1-3, is characterized in that: the additive also comprising 1-9 weight part.
5. the liver-protecting white spirit of alcohol tolerance liver injury as claimed in claim 4, is characterized in that: described additive, comprises the component of following weight parts: 3-hydroxyl-2-ethyl-pyrokomane 10-30 part, Xylitol 20-40 part, carrageenin 10-20 part.
6. the preparation method of the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 1-3, is characterized in that, comprise the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter.
7. preparation method as claimed in claim 6, is characterized in that: step (1) described soak time is 15-30 days.
8. the preparation method of the liver-protecting white spirit of the alcohol tolerance liver injury according to any one of claim 4-5, is characterized in that, comprise the steps:
(1) each raw material is taken by proportioning, by pawpaw, the root of kudzu vine, hawthorn and wolfberry fruit are put into white wine and are soaked;
(2) adsorb with active carbon for liquor, filter;
(3) additive is added.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510086520.3A CN104630009B (en) | 2015-02-23 | 2015-02-23 | Liver-protecting white spirit of resisting alcoholic hepatic injury and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510086520.3A CN104630009B (en) | 2015-02-23 | 2015-02-23 | Liver-protecting white spirit of resisting alcoholic hepatic injury and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104630009A true CN104630009A (en) | 2015-05-20 |
CN104630009B CN104630009B (en) | 2016-06-08 |
Family
ID=53209263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510086520.3A Expired - Fee Related CN104630009B (en) | 2015-02-23 | 2015-02-23 | Liver-protecting white spirit of resisting alcoholic hepatic injury and preparation method thereof |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104630009B (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109136025A (en) * | 2018-07-11 | 2019-01-04 | 山西三十七度酒业有限公司 | A kind of composite fragrant assembled alcoholic drinks and its preparation method |
CN109306308A (en) * | 2017-07-27 | 2019-02-05 | 甄青松 | A kind of odor type health white wine |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5558087A (en) * | 1978-10-23 | 1980-04-30 | Sumie Hihara | Low calorie apricot liquor |
CN1153818A (en) * | 1996-10-23 | 1997-07-09 | 宁夏农林科学院农副产品贮藏加工研究所 | Fresh lycium chinense with stalk wine and its brewage process |
CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
CN102660445A (en) * | 2012-06-06 | 2012-09-12 | 重庆修贤商贸有限公司 | Functional low-damage healthcare wine |
CN103103097A (en) * | 2013-01-16 | 2013-05-15 | 丽水市林业科学研究院 | Rhizoma polygonati kidney tonifying wine and preparation method thereof |
CN103666982A (en) * | 2012-09-08 | 2014-03-26 | 哈尔滨艾克尔食品科技有限公司 | Pineapple jelly wine |
-
2015
- 2015-02-23 CN CN201510086520.3A patent/CN104630009B/en not_active Expired - Fee Related
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5558087A (en) * | 1978-10-23 | 1980-04-30 | Sumie Hihara | Low calorie apricot liquor |
CN1153818A (en) * | 1996-10-23 | 1997-07-09 | 宁夏农林科学院农副产品贮藏加工研究所 | Fresh lycium chinense with stalk wine and its brewage process |
CN101874857A (en) * | 2010-05-28 | 2010-11-03 | 劲牌有限公司 | Liver-protecting white spirit for resisting alcoholic liver injury and production process thereof |
CN102660445A (en) * | 2012-06-06 | 2012-09-12 | 重庆修贤商贸有限公司 | Functional low-damage healthcare wine |
CN103666982A (en) * | 2012-09-08 | 2014-03-26 | 哈尔滨艾克尔食品科技有限公司 | Pineapple jelly wine |
CN103103097A (en) * | 2013-01-16 | 2013-05-15 | 丽水市林业科学研究院 | Rhizoma polygonati kidney tonifying wine and preparation method thereof |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109306308A (en) * | 2017-07-27 | 2019-02-05 | 甄青松 | A kind of odor type health white wine |
CN109136025A (en) * | 2018-07-11 | 2019-01-04 | 山西三十七度酒业有限公司 | A kind of composite fragrant assembled alcoholic drinks and its preparation method |
Also Published As
Publication number | Publication date |
---|---|
CN104630009B (en) | 2016-06-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103865717B (en) | A kind of health preserving wine and preparation method thereof | |
US9987324B2 (en) | Traditional chinese medicine composition and the use thereof | |
CN111374297A (en) | Compound salt and preparation method thereof | |
CN103865720A (en) | Refined astragalus mongholicus health wine and preparation method thereof | |
CN104630010B (en) | Tonic health preserving wine and preparation method thereof | |
CN104694356B (en) | Radix Ginseng liver-protection health-care wine and preparation method thereof | |
CN103602551A (en) | Compound traditional Chinese medicinal herbal fermented health-care liquor for promoting digestion and strengthening stomach and production method thereof | |
CN104560577A (en) | Distilled spirit with function of resisting fatigue and preparation method of distilled spirit | |
CN104630009B (en) | Liver-protecting white spirit of resisting alcoholic hepatic injury and preparation method thereof | |
CN106538908A (en) | A kind of grape drink for improving the health care of sleep and manufacture method | |
CN105331510A (en) | Grape and purple yam vinegar | |
CN105695236A (en) | Formula and production process for health maintenance and healthcare wine | |
KR102452902B1 (en) | Herbal medicinal liquor and its manufacturing method | |
KR101327802B1 (en) | Fermented extract of eel and manufacturing process of the same | |
CN104560579A (en) | Health white spirit with functions of tonifying liver and tonifying kidney and preparation method of health white spirit | |
CN102524868A (en) | Concentrated pulp containing red jujube, autumn pear and loquat | |
KR102058298B1 (en) | Method for manufacturing hangover curing agent | |
CN102417877A (en) | Health-preserving wine | |
CN105331511A (en) | Grape and winged yam rhizome vinegar | |
CN104560575A (en) | Health white spirit with functions of tonifying kidney and strengthening Yang and preparation method of health white spirit | |
CN104745416B (en) | Healthcare white spirit for tonifying Qi and strengthening spleen and preparation method thereof | |
KR102636322B1 (en) | Method for manufacturing dried yellow corvina with gochujang and dried yellow corvina with gochujang produced thereby | |
KR102621081B1 (en) | Method for manufacturing seasoning sauce for shellfish and seafood | |
CN108783341A (en) | A kind of the tea sauce formulation and production technology of the chrysanthemum medlar pyrus nivalis flavor of heat-clearing improving eyesight | |
CN104587099B (en) | Antilipemic healthy white wine and preparation method thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CP01 | Change in the name or title of a patent holder | ||
CP01 | Change in the name or title of a patent holder |
Address after: No. 3552, room 3, No. 200, Huan Cheng Road, Shanghai, Shanghai Patentee after: Neu (Shanghai) Food Technology Co., Ltd. Address before: No. 3552, room 3, No. 200, Huan Cheng Road, Shanghai, Shanghai Patentee before: Wine pocket (Shanghai) Klc Holdings Ltd |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20160608 Termination date: 20210223 |