CN104545812A - Detection depth adjustable non-invasive detection device for human body biochemical criteria - Google Patents

Abstract

The non-invasive detection device for human biochemical indicators with controllable detection depth belongs to the field of optics and sensing technology. In order to solve the problem that the existing technology cannot measure skin tissue at a specific depth, the near-infrared light emitted by the light source of the device is transmitted through the incident optical fiber. Into the probe head, the probe head is in contact with the surface of the human skin, the incident light is projected onto the surface of the human skin, and enters the outgoing optical fiber after being reflected and scattered on the skin surface. The outgoing optical fiber has three groups of optical fibers with different core distances. The three groups of optical fibers are respectively Conducted to the first detector, the second detector and the third detector, and each detector converts the optical signal into an electrical signal to achieve the purpose of detection; the invention realizes the non-invasive detection of human biochemical indicators with controllable detection depth.

Description

Non-invasive detection device for human biochemical indicators with controllable detection depth

technical field

The invention relates to a non-invasive detection device for human body biochemical indicators with controllable detection depth, belonging to the field of optics and sensing technology.

Background technique

The biochemical composition of human epidermis is of great significance in both clinical and research fields. Among them, moisture, oil, etc. can be used as important indicators for judging the skin quality and health of the human body, and the physiological indicators such as sugar, lipid, and hemoglobin in the epidermis and dermis have a large degree of correlation with the corresponding indicators in the blood. Sex, blood sugar, blood lipids, hemoglobin and other indicators can be obtained through optical analysis of the epidermis.

In the near-infrared non-invasive detection of human epidermal biochemical indicators, the near-infrared light is incident on the human epidermal tissue from the light source, and after being absorbed and scattered by the human tissue, the corresponding absorption spectrum is obtained in the outgoing light. The predicted value of various biochemical indicators in the human epidermis can be obtained through the modeling and analysis of the spectrum, which can be applied to clinical detection and monitoring, and has extremely high clinical value.

The universal probe used in the near-infrared non-invasive detection process cannot achieve the best detection effect, and its main shortcomings are:

1. Since the distance between the incident optical fiber and the outgoing optical fiber has not been precisely calculated and designed, the universal optical fiber probe cannot perform special measurements on skin tissue at a specific depth.

2. It is often difficult for the universal probe to fit the skin tissue, which may easily cause discomfort, and some parts cannot be detected.

Contents of the invention

In order to solve the problem that the existing technology cannot perform special measurement of skin tissue at a specific depth, the present invention proposes a non-invasive detection device for human biochemical indicators with controllable detection depth.

The technical scheme that the present invention solves technical problem is:

The non-invasive detection device for human biochemical indicators with controllable detection depth is characterized in that the near-infrared light emitted by the light source is transmitted to the detection head through the incident optical fiber, and the detection head is in contact with the surface of the human skin, and the incident light is projected on the surface of the human skin. After the reflection and scattering of the skin surface, it enters the outgoing optical fiber. The outgoing optical fiber has three groups of optical fibers with different core distances. The three groups of optical fibers are respectively transmitted to the detectors 1, 2 and 3. Each detector converts the optical signal into an electrical signal. signal to achieve the purpose of detection.

The beneficial effects of the present invention are:

The invention realizes the non-invasive detection of human biochemical indexes with controllable detection depth through the special structural design of the incident optical fiber and the outgoing optical fiber. The incident fiber is surrounded by multiple layers of outgoing fibers, and the fiber core distance increases layer by layer from the inside to the outside. Such an optical fiber core distance can enable the probe to detect skin tissue at a specific depth. For human skin, the signal of the stratum corneum layer is the strongest in the spectrum detected by the optical fiber with a shorter core distance; The signal is strongest in the middle dermis. Since the surface of the probe is in direct contact with the skin of the human body, in order to avoid pollution and interference and reduce the difficulty of cleaning, the present invention adds a layer of glass on the contact surface between the probe and the skin to make it easier to fit the skin. At the same time, the probe is reinforced with a rigid metal material at the probe tip.

Description of drawings

Fig. 1 is a schematic diagram of a non-invasive detection device for human biochemical indicators with controllable detection depth according to the present invention.

In the figure: 1. Optical fiber, 2. Light source, 3-1, Detector 1, 3-2, Detector 2, 3-3, Detector 3, 4. Probe head, 1-1, Incident fiber, 1-2 , Outgoing optical fiber.

Fig. 2 is a schematic diagram of the structure of each optical fiber of the present invention.

In the figure: A, cross-section of incident fiber, B, cross-section of optical fiber inside the probe, C, cross-section of 0.2mm outgoing fiber, D, cross-section of 0.6mm outgoing fiber, E, cross-section of 1.0mm outgoing fiber.

1-4, incident fiber core, 1-5, shorter core distance exit fiber core, 1-6, medium core distance exit fiber core, 1-7, longer core distance exit fiber core, 1-8, insulating plastic, 1-9. Metal hoses.

Detailed ways

The present invention will be described in further detail below in conjunction with the accompanying drawings.

As shown in Figure 1, in the non-invasive detection device for human biochemical indicators with controllable detection depth, the near-infrared light emitted by the light source 2 is transmitted to the detection head 4 through the incident optical fiber 1-1, and the detection head 4 is in contact with the surface of human skin, and the incident light Projected onto the surface of the human skin, after reflection and scattering on the skin surface, it enters the outgoing optical fiber 1-2. The outgoing optical fiber 1-2 has three sets of optical fiber cores with different core distances, and the three sets of optical fiber cores are respectively transmitted to the detector 1-3. -1. In the second detector 3-2 and the third detector 3-3, each detector converts the optical signal into an electrical signal to achieve the purpose of detection.

As shown in Figure 2, the incident fiber 1-1 is located at the center of the probe head 4, and a short core distance is set around the incident fiber 1-1 at a core distance of 0.2mm. Long-distance outgoing optical fiber cores 1-7 are arranged at a distance of 1-6 from the outgoing optical fiber cores and a distance of 1.0 mm. At these three distances, near-infrared light can detect the spectral signals of the stratum corneum, epidermis and dermis of human skin. Since the farther the incident fiber core 1-4 from the center is, the longer the distance that the near-infrared light propagates in human tissue is, and the weaker the outgoing signal is, so the closer to the outer layer, the denser the outgoing fiber core is to increase the strength of the signal. Among them, there are 4 outgoing optical fiber cores 1-5 with a shorter core distance, 12 outgoing optical fiber cores 1-6 with a medium core distance, and 16 outgoing optical fiber cores 1-7 with a longer core distance.

The material of optical fiber 1 among the present invention is identical, and the surrounding of each optical fiber core of its interior is the insulating plastic 1-8 that has certain flexibility, plays fixing optical fiber 1 and makes it have certain strength and toughness; The outer layer is a stainless steel hose 1-9, so that the optical fiber 1 has good rigidity and has a limited bending radius, which plays a role in protecting the optical fiber 1 . The bending radius of the stainless steel hose 1-9 is relatively small among the incident optical fiber 1-1 and the outgoing optical fiber 1-2, the short-core distance outgoing optical fiber core 1-5 in the outgoing optical fiber 1-2, and the medium-core distance outgoing optical fiber core 1- 6 and long-core-distance outgoing fiber cores 1-7 are more, and the bending radius is larger. The three arrangements of outgoing optical fibers 1-2 are all center-symmetrical, and can also be densely arranged in the center to ensure the uniformity of outgoing light.

The probe head 4 will be in direct contact with the skin, and its probe front end is covered with a glass protective layer 4-1, which can protect the incident optical fiber core 1-4, the short-core distance outgoing optical fiber core 1-5, the center-core distance outgoing optical fiber core 1-6 and The long-distance outgoing fiber cores 1-7 are protected from external contamination and are easy to clean. The front part of the detection head 4 is covered by a rigid metal layer 4-2, which is convenient for other equipment to fix it.

Claims (3)

1. A non-invasive detection device for human biochemical indicators with controllable detection depth, characterized in that the near-infrared light emitted by the light source (2) is transmitted to the detection head (4) through the incident optical fiber (1-1), and the detection head (4) and When the surface of the human skin is in contact, the incident light is projected onto the surface of the human skin, and enters the outgoing optical fiber (1-2) after being reflected and scattered on the skin surface. The outgoing optical fiber (1-2) has three groups of fibers with different core distances. The optical fibers are respectively transmitted to the first detector (3-1), the second detector (3-2) and the third detector (3-3), and each detector converts the optical signal into an electrical signal to achieve the purpose of detection. 2. The human body biochemical index non-invasive detection device with controllable detection depth according to claim 1, characterized in that, the center of the detection head (4) is the incident optical fiber (1-1), and the incident optical fiber (1-1) Short-core-pitch outgoing fibers (1-5), medium-core-pitch outgoing fibers (1-6) and long-core-pitch outgoing fibers (1-7) are respectively arranged at different distances around. 3. the human body biochemical indicator non-invasive detection device with controllable detection depth according to claim 1, is characterized in that, the probe head (4) probe front end is covered with glass protective layer (4-1); Covered by a rigid metal layer (4-2).