CN104127847A

CN104127847A - Traditional Chinese medicine composition for treating femoral head necrosis

Info

Publication number: CN104127847A
Application number: CN201410384500.XA
Authority: CN
Inventors: 殷波
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-08-07
Filing date: 2014-08-07
Publication date: 2014-11-05

Abstract

The invention relates to a traditional Chinese medicine composition for treating femoral head necrosis. The traditional Chinese medicine composition is prepared from the following raw medicinal materials by weight: 30g of manis pentadactyla, 30g of zaocys dhumnade, 15g of keel, 20g of rehmannia glutinosa, 20g of astragalus, 15g of angelica sinensis, 20g of achyranthes root, 30g of leech, 25g of scorpio, 25g of centipede, 20g of tortoise plastron, 20g of deer-horn glue, 30g of the root of red-rooted salvia, 20g of lycopodium clavatum, 25g of gentiana macrophylla, 20g of frankincense, 20g of myrrh, 20g of teasel root, 30g of pseudo-ginseng, 20g of caulis spatholobi, 20g of divaricate saposhnikovia root, 20g of eucommia ulmoides, 20g of cordyceps sinensis, 15g of rhizoma zingiberis, 40g of gastrodia elata, 30g of malt, 30g of dried tangerine or orange peel, 30g of poria cocos, 25g of garden balsam stem, 25g of American ginseng, 30g of platycodon grandiflorum and 10g of liquorice. The traditional Chinese medicine composition has an obvious curative effect on the femoral head necrosis.

Description

A kind of Chinese medicine composition for the treatment of femur head necrosis

Technical field

The present invention relates to a kind of Chinese medicine for the treatment of femur head necrosis, belong to Chinese medicine technical field.

Background technology

Femur head necrosis is again ischemic necrosis of femoral head, for one of common osteoarthritis, the cause of disease of femur head necrosis is varied, but its common pathomechanism is osseous tissue ischemia, this theory is thought, in various bones, outer paathogenic factor causes that osseous tissue nutritional blood flow reduces, vasoganglion pressurized or outflow vein obstruction in bone, cause local blood for obstacle, severe patient can cause osseous tissue ischemic necrosis, motherland's medical science is thought, femur head necrosis is to wait exopathogen invasion and attack human body because wind and cold is damp and hot, make meridians obturation, blood-vessel obstructive, QI-blood circulation is not smooth, so that muscles and bones muscle numb pain, joint stuffiness, very cause joint ischemia, distortion, amyotrophy, serious moving obstacle, local tissue necrosis, apraxia causes.Femur head necrosis is a complicated pathological process, as do not treated timely and effectively in early days, will make ischemic femoral head, subside, joint space narrows, finally cause osteoarthrosis inflammation, necrosis, make patient's hip joint function obstacle and the paralysis of disabling, patient is in suffering physiology slight illness, also to suffer decocting of psychic trauma, increase white elephant also to family, unit and society.The medicine for the treatment of femur head necrosis is a lot of at present, also have certain therapeutic effect, but therapeutic effect is little significantly.

Summary of the invention

In order to solve the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of femur head necrosis.

The present invention is prepared from by the crude drug of following weight: Squama Manis 30g, Zaocys 30g, Os Draconis 15g, Radix Rehmanniae Preparata 20g, Radix Astragali 20g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 20g, Hirudo 30g, Scorpio 25g, Scolopendra 25g, Carapax et Plastrum Testudinis 20g, Colla cornus cervi 20g, Radix Salviae Miltiorrhizae 30g, Herba Lycopodii 20g, Radix Gentianae Macrophyllae 25g, Olibanum 20g, Myrrha 20g, Radix Dipsaci 20g, Radix Notoginseng 30g, Caulis Spatholobi 20g, Radix Saposhnikoviae 20g, Cortex Eucommiae 20g, Cordyceps 20g, Rhizoma Zingiberis 15g, Rhizoma Gastrodiae 40g, Fructus Hordei Germinatus 30g, Pericarpium Citri Reticulatae 30g, Poria 30g, Herba speranskiae tuberculatae 25g, Radix Panacis Quinquefolii 25g, Radix Platycodonis 30g, Radix Glycyrrhizae 10g.

Preparation method: get above each taste, mix, pulverize, add suitable quantity of water, be prepared into piller, dry, to obtain final product.

Instructions of taking: take 2-3 every day, each 3-5 gram, taking medicine after meal.

The present invention can also adopt modern pharmaceutical technology to adopt other preparation methoies as the effective ingredient in the method extraction medicines such as conventional water extraction, alcohol extraction, diafiltration, supercritical extraction, and can add pharmaceutically the adjuvant allowing to be prepared into other dosage form, as powder, big honeyed pills, tablet, granule, capsule, drop pill, slow controlled-release target preparation etc.

clinical data

Case source

Choose case 100 examples that are diagnosed as femur head necrosis, get rid of relative similar disease, and merge the heart, cerebrovascular disease, the abnormal person of hepatic and renal function, wherein male 62 examples, female's 38 examples; Between age 21-71 year, average 56.3 years old; The elder of the course of disease 6 years, the shortest person 3 months, wherein I phases 26 hip, II phases 35 hip, III phases 33 hip, IV phases 71 hip, totally 165 hips.The standard that by stages can specify with reference to international bone circulation science: i.e. 0 phase: x line sheet, MR I, E C T are all normal, only could find osteonecrosis taking out when tissue in femoral head carries out cut sections for microscopic examination; The I phase: X-ray film is normal, MRI, ECT image can note abnormalities; The II phase: x line sheet, MRI, E C T all can note abnormalities, but femoral head profile is normal; The III phase: x line sheet shows that femoral head has slightly and subsides; The IV phase: X-ray film shows that collapse of the femoral head flattens; The V phase: X-ray film shows that hip joint space narrows.

Therapeutic Method

Adopt the medicine prepared of the present invention, take 2-3 every day, each 6-9 gram, and taking medicine after meal, one month is a course for the treatment of, treat observe the curative effect after 3 courses for the treatment of, avoids heavy burden during treatment, alleviating alcohol addiction is given up smoking.

Criterion of therapeutical effect

Cure: hip joint is without pain, and lower limb are without cripetura, and function is recovered completely, and imaging examination is normal.

Take a turn for the better: the hip arthralgia obviously alleviates, and hip joint movable function is good, lower limb shortening is less than l c m, and iconography femur head necrosis phenomenon is improved.

Invalid: the hip arthralgia is without obvious alleviation, and lower limb shortening is greater than l c m, X-ray film, C T check that femoral head becomes large or flat, and osteonecrosis phenomenon is unchanged.

Therapeutic outcome

Therapeutic outcome is as following table:

By stages	Total hip number	Cure	Take a turn for the better	Invalid	Effective percentage (%)
						The I phase	26	22	4	0	100
The II phase	35	20	13	2	94.3
						The III phase	33	9	22	2	93.9
The IV phase	71	1	50	20	71.8
						Add up to	165	52	89	24	85.5

From above clinical data, medicine of the present invention is better to the therapeutic effect of III phase to the I phase, and its effective percentage is respectively 100%, 94.3% and 93.6%, and total effective rate reaches 85.5%, illustrates that medicine of the present invention has significant curative effect to femur head necrosis.

Detailed description of the invention

Below in conjunction with embodiment, the present invention is further illustrated.

embodiment 1

Get Squama Manis 30g, Zaocys 30g, Os Draconis 15g, Radix Rehmanniae Preparata 20g, Radix Astragali 20g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 20g, Hirudo 30g, Scorpio 25g, Scolopendra 25g, Carapax et Plastrum Testudinis 20g, Colla cornus cervi 20g, Radix Salviae Miltiorrhizae 30g, Herba Lycopodii 20g, Radix Gentianae Macrophyllae 25g, Olibanum 20g, Myrrha 20g, Radix Dipsaci 20g, Radix Notoginseng 30g, Caulis Spatholobi 20g, Radix Saposhnikoviae 20g, Cortex Eucommiae 20g, Cordyceps 20g, Rhizoma Zingiberis 15g, Rhizoma Gastrodiae 40g, Fructus Hordei Germinatus 30g, Pericarpium Citri Reticulatae 30g, Poria 30g, Herba speranskiae tuberculatae 25g, Radix Panacis Quinquefolii 25g, Radix Platycodonis 30g, Radix Glycyrrhizae 10g, mix, pulverize, add suitable quantity of water, be prepared into piller, dry, obtain.

Claims

1. treat the Chinese medicine composition of femur head necrosis for one kind, it is characterized in that, crude drug by following weight is prepared from: Squama Manis 30g, Zaocys 30g, Os Draconis 15g, Radix Rehmanniae Preparata 20g, Radix Astragali 20g, Radix Angelicae Sinensis 15g, Radix Achyranthis Bidentatae 20g, Hirudo 30g, Scorpio 25g, Scolopendra 25g, Carapax et Plastrum Testudinis 20g, Colla cornus cervi 20g, Radix Salviae Miltiorrhizae 30g, Herba Lycopodii 20g, Radix Gentianae Macrophyllae 25g, Olibanum 20g, Myrrha 20g, Radix Dipsaci 20g, Radix Notoginseng 30g, Caulis Spatholobi 20g, Radix Saposhnikoviae 20g, Cortex Eucommiae 20g, Cordyceps 20g, Rhizoma Zingiberis 15g, Rhizoma Gastrodiae 40g, Fructus Hordei Germinatus 30g, Pericarpium Citri Reticulatae 30g, Poria 30g, Herba speranskiae tuberculatae 25g, Radix Panacis Quinquefolii 25g, Radix Platycodonis 30g, Radix Glycyrrhizae 10g.