CN103109980A - Chinese herbal medicine feed additive capable of improving immunity, preparation method thereof and feed - Google Patents
Chinese herbal medicine feed additive capable of improving immunity, preparation method thereof and feed Download PDFInfo
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- CN103109980A CN103109980A CN2013100686473A CN201310068647A CN103109980A CN 103109980 A CN103109980 A CN 103109980A CN 2013100686473 A CN2013100686473 A CN 2013100686473A CN 201310068647 A CN201310068647 A CN 201310068647A CN 103109980 A CN103109980 A CN 103109980A
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- feed additive
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Abstract
本发明提供一种提高免疫力的中草药饲料添加剂,其特征在于,其组成成分以及重量数为:千屈菜、红背菜、山药、淫羊藿、焦神曲、鸡血藤、葛根、升麻、芍药、建曲、大黄、厚朴、贯众、甘草、黄芩、忍冬藤、绞股蓝、茯苓、大豆异黄酮、大豆皂甙、附加成分,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。本发明代替抗生素和药物的使用,既无任何毒副作用,又可明显提高动物的体质,例如仔猪、鸡鸭等,以较低的投入获取较高的经济效益,还无抗生素和化学药物残留,为减少动物性制品中抗生素残留提供有效途径。The invention provides a Chinese herbal medicine feed additive for improving immunity, which is characterized in that its composition and weight are as follows: chrysanthemum chinensis, red back vegetable, yam, epimedium, Jiao Shenqu, Caulis Spatholobus, kudzu root, Cimicifuga , peony, Jianqu, rhubarb, Magnolia officinalis, Guanzhong, licorice, baicalin, honeysuckle, gynostemma, Poria cocos, soybean isoflavones, soybean saponins, additional ingredients, the additional ingredients are vitamin A, vitamin B, vitamin C, three Chromium chloride, xanthan gum, xylitol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1. The present invention replaces the use of antibiotics and medicines, without any toxic and side effects, and can obviously improve the physique of animals, such as piglets, chickens and ducks, etc., obtains higher economic benefits with lower investment, and has no antibiotics and chemical drug residues. Provide an effective way to reduce antibiotic residues in animal products.
Description
技术领域technical field
本发明属于畜牧行业的饲料领域,尤其涉及一种提高免疫力的中草药饲料添加剂、制备方法及饲料。The invention belongs to the feed field of the animal husbandry industry, and in particular relates to a Chinese herbal medicine feed additive for improving immunity, a preparation method and a feed.
背景技术Background technique
腹泻是养猪生产中的一种典型的多因素疾病,据统计,仔猪腹泻的发病率为35%,其间接损失又表现在治愈仔猪生长发育迟缓,饲料转化率低,严重威胁养猪业的发展。自2006年5月以来,在全国各地先后爆发流行猪高热病,引起大批猪只发病死亡,造成重大的经济损失。直至目前,高热病仍在全国22个省份的猪群中发生流行,危害猪只的健康生长,威胁着养猪业的发展。抗生素在养殖中的使用所带来的不良后果大家都已充分认识。许多专家都认为在全国很多地区广泛流行的“猪高热病”的一个重要原因是猪的免疫力低下,抗病力低。Diarrhea is a typical multifactorial disease in pig production. According to statistics, the incidence rate of piglet diarrhea is 35%, and its indirect loss is manifested in the growth retardation of cured piglets and low feed conversion rate, which seriously threatens the pig industry. develop. Since May 2006, pig hyperthermia has broken out successively throughout the country, causing a large number of pigs to become ill and die, resulting in significant economic losses. Up to now, high fever is still prevalent in pig herds in 22 provinces of the country, endangering the healthy growth of pigs and threatening the development of pig industry. The adverse consequences of the use of antibiotics in farming have been fully recognized by everyone. Many experts believe that an important reason for the widespread "swine high fever" in many parts of the country is the low immunity and low disease resistance of pigs.
上世纪中期,动物学家发现在饲料中添加低剂量的抗生素可以明显的促进畜禽的生长,随即其在饲料中广泛的使用。据统计在世界上有20多种的抗生素以及十几种的合成抗菌药物在饲料中的使用。饲料抗生素在预防动物疾病,促进动物生长,提高饲料报酬都起到了积极的作用。但是,长期使用抗生素会产生耐药性,一方面使抗生素变得无效,另一方面造成抗生素的滥用,严重危害人类健康;随着时间的发展,细菌的抗药性的增加、畜产品的药物残留等问题已经对人体健康构成了严重的威胁,饲用抗生素所导致的负面的效应成为人们灌注的焦点。绿色、无污染、有效的抗生素的替代产品是未来畜牧业发展的趋势,这对促进我国畜牧业的发展,保障人们身体健康具有深远的意义。在饲料和饲养过程中添加、使用大量的抗生素或化学药物,这样虽然抗细菌性腹泻效果好,但对病毒性腹泻无效,且药物残留严重,不符合人们日益关注的食品安全和健康养殖发展趋势。In the middle of the last century, zoologists discovered that adding low-dose antibiotics to feed can significantly promote the growth of livestock and poultry, and then it was widely used in feed. According to statistics, there are more than 20 kinds of antibiotics and more than ten kinds of synthetic antibacterial drugs used in feed in the world. Feed antibiotics play a positive role in preventing animal diseases, promoting animal growth, and increasing feed remuneration. However, long-term use of antibiotics will produce drug resistance. On the one hand, the antibiotics will become ineffective, and on the other hand, the abuse of antibiotics will seriously endanger human health. With the development of time, the increase of bacterial resistance and the drug residues in animal products Such problems have constituted a serious threat to human health, and the negative effects caused by feeding antibiotics have become the focus of people's perfusion. Green, pollution-free, and effective alternatives to antibiotics are the future development trend of animal husbandry, which has far-reaching significance for promoting the development of animal husbandry in my country and ensuring people's health. Adding and using a large amount of antibiotics or chemical drugs in the feed and feeding process, although the effect of anti-bacterial diarrhea is good, it is ineffective against viral diarrhea, and the drug residues are serious, which does not conform to the growing trend of food safety and healthy breeding. .
当前,在我国饲料行业中,随着《饲料和饲料添加剂管理条例》颁布和执行要求,禁止滥用药物添加剂,饲料添加剂可选择范围越来越小,而有生命的促长剂和保健剂的微生态制剂是最大亮点。At present, in my country's feed industry, with the promulgation and implementation requirements of the "Regulations on the Administration of Feed and Feed Additives", the abuse of drug additives is prohibited, and the range of options for feed additives is getting smaller and smaller. Ecological preparations are the biggest highlight.
我国中药的应用已经越来越得到国际社会的认可,其多种药材疗效显著,通过大量试验和研究,发现加入复合有一定量中药的饲料,代替抗生素,提高动物免疫力有显著效果,能够有效对抗炎症和感染,保证动物肠道的健康,防治动物下痢,提高动物生产性能,尤其是加入一定配比量的配料后,效果明显加强。中草药以其资源丰富,作用广泛、不会产生耐药性等优点倍受青睐。本发明提供提高一种提高免疫力的中草药饲料添加剂,代替抗生素和抗寄生虫药物,避免了药物残留和抗生素耐药弊端。经对现有技术的文献检索,尚末发现与本发明的提高动物免疫力及抗感染的中草药饲料添加剂有关的报道。The application of traditional Chinese medicine in my country has been more and more recognized by the international community. Its various medicinal materials have remarkable curative effects. Through a large number of experiments and researches, it was found that adding a feed compounded with a certain amount of traditional Chinese medicine, instead of antibiotics, has a significant effect on improving animal immunity and can effectively fight against Inflammation and infection, ensuring the health of animal intestines, preventing animal diarrhea, and improving animal production performance, especially after adding a certain proportion of ingredients, the effect is significantly enhanced. Chinese herbal medicine is favored for its rich resources, wide range of effects, and no drug resistance. The invention provides a Chinese herbal medicine feed additive for improving immunity, which replaces antibiotics and antiparasitic drugs, and avoids the drawbacks of drug residues and antibiotic resistance. After searching the literature of the prior art, no report related to the Chinese herbal medicine feed additive for improving animal immunity and anti-infection of the present invention has been found.
发明内容Contents of the invention
一种提高免疫力的中草药饲料添加剂,其特征在于,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, characterized in that its components and parts by weight are: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-30 parts of epimedium 35 parts, 10-20 parts of Jiao Shenqu, 10-20 parts of Caulis Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, Magnolia officinalis 2-5 parts, Guanzhong 2-5 parts, licorice 3-10 parts, scutellaria baicalensis 5-8 parts, honeysuckle vine 5-8 parts, Gynostemma pentaphyllum 2-5 parts, Poria cocos 2-5 parts, soybean isoflavone 0.15 parts , 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components The distribution ratio is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、麦芽3~5份、磷酸氢钙1~3份、呈味肽1~3份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-35 parts of epimedium, coke 10-20 parts of Divine Comedy, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, 2-2 parts of Magnolia officinalis 5 parts, 2-5 parts of rhubarb, 3-10 parts of licorice, 5-8 parts of skullcap, 5-8 parts of honeysuckle, 2-5 parts of Gynostemma, 2-5 parts of Poria cocos, 3-5 parts of malt, calcium hydrogen phosphate 1-3 parts, 1-3 parts of taste peptide, 0.15 parts of soybean isoflavone, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, yellow element Glue, xylitol, and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、溶菌酶0.5~8份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 0.5-8 parts of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、石粉5~10份、碘酸钾1~5份、L-肉碱5~10份、溶菌酶0.5~8份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 5-10 parts of stone powder, 1-5 parts of potassium iodate, L-carnitine 5-10 parts, 0.5-8 parts of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、石粉5~10份、碘酸钾1~5份、L-肉碱5~10份、溶菌酶0.5~8份、核苷酸1~5份、溶葡萄球菌酶1~3份、蛋氨酸1~3份、叶酸1~2份,β-葫萝卜素1~2份、酸化剂1~3份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 5-10 parts of stone powder, 1-5 parts of potassium iodate, L-carnitine 5-10 parts, 0.5-8 parts of lysozyme, 1-5 parts of nucleotides, 1-3 parts of lysostaphin, 1-3 parts of methionine, 1-2 parts of folic acid, 1-2 parts of β-carotene , Acidifier 1 to 3 parts.
一种提高免疫力的中草药饲料添加剂制作的饲料,所述酸化剂为酸化剂为柠檬酸、延胡索酸、丙酸、甲酸或乳酸。A feed made of a Chinese herbal medicine feed additive for improving immunity, wherein the acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
一种提高免疫力的中草药饲料添加剂制作的方法,其特征在于步骤如下:A method for making a Chinese herbal medicine feed additive for improving immunity, characterized in that the steps are as follows:
1)选用市售的超微粉碎机;1) Select a commercially available ultrafine pulverizer for use;
2)根据超微粉碎机的一次吞吐量称取相应量的千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。2) According to the one-time throughput of the ultrafine pulverizer, weigh the corresponding amount of 10-30 parts of Chidren, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-35 parts of epimedium, and 10-20 parts of Jiao Shenqu. 20 parts, 10-20 parts of Mildew Spatholobus, 10-20 parts of kudzu root, 10-15 parts of cohosh, 10-15 parts of peony, 4-8 parts of Jianqu, 4-8 parts of rhubarb, 2-5 parts of magnolia bark, 2-5 parts of Rhizome, 3-10 parts of licorice, 5-8 parts of Scutellaria baicalensis, 5-8 parts of Lonicera vine, 2-5 parts of Gynostemma pentaphyllum, 2-5 parts of Poria cocos, 0.15 parts of soybean isoflavone, 1.5 parts of soybean saponin, additional 10 parts of ingredients, the additional ingredients are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, and mannitol crystals, and the proportioning ratio of each component of the additional ingredients is 0.2:0.2: 0.5:0.3:1:1:1.
步骤一、按上述配比称取上述各成分,即千屈菜、红背菜、山药、淫羊藿、焦神曲、鸡血藤、葛根、升麻、芍药、建曲、大黄、厚朴、贯众、甘草、黄芩、忍冬藤、绞股蓝、茯苓,通过超微粉碎机,粉碎后制成超微粉剂至200目待用;所述千屈菜、红背菜是将干燥后的含水量在9wt%以下的根、茎叶、花,置于炒制锅中于130~150℃炒制10分钟,直至表面发黄为止,即取出备用;Step 1. Weigh the above-mentioned ingredients according to the above-mentioned ratio, that is, quinces, red back vegetables, yam, epimedium, Jiao Shenqu, Caulis Spatholobus, kudzu root, cohosh, peony, Jianqu, rhubarb, Magnolia officinalis, Guanzhong, Radix Glycyrrhizae, Scutellaria baicalensis, Lonicerae vine, Gynostemma pentaphyllum, Poria cocos are made into ultrafine powder to 200 orders after being pulverized by an ultrafine pulverizer; Roots, stems, leaves, and flowers with less than 9 wt% are placed in a frying pan and fried at 130-150°C for 10 minutes until the surface turns yellow, and then taken out for later use;
步骤二、按照配比称取粉剂形状的大豆异黄酮、大豆皂甙以及所述附加成分;Step 2, weighing soybean isoflavones, soybean saponins and the additional components in powder form according to the proportioning ratio;
将上述步骤一、二得到的粉剂混合,然后搅匀、在摄氏60℃下减压干燥、灭菌、包装即得到所述提高免疫力的中草药饲料添加剂。The powders obtained in the above steps 1 and 2 are mixed, then evenly stirred, dried under reduced pressure at 60° C., sterilized, and packaged to obtain the immunity-enhancing Chinese herbal medicine feed additive.
按上述制备方法,每份50克。Prepared as above, 50 grams per serving.
有益效果:Beneficial effect:
本发明所用中草药均为价格低廉的常用药物,将其制成动物饲料添加剂服用,代替抗生素和药物的使用,既无任何毒副作用,又可明显提高动物的体质,例如仔猪、鸡鸭等,以较低的投入获取较高的经济效益,还无抗生素和化学药物残留,为减少动物性制品中抗生素残留提供有效途径。将天然中草药组成的药剂作为饲料添加剂饲喂动物,可增强体质,提高机体免疫力,对增强传染性疾病、致病性微生物和寄生虫的抵抗力和提高肉质和产量有显著作用。The Chinese herbal medicines used in the present invention are commonly used medicines with low price, and they are taken as animal feed additives to replace the use of antibiotics and medicines, without any toxic and side effects, and can obviously improve the physique of animals, such as piglets, chickens and ducks, etc. Lower investment can obtain higher economic benefits, and there are no antibiotic and chemical drug residues, which provides an effective way to reduce antibiotic residues in animal products. Feeding animals composed of natural Chinese herbal medicines as feed additives can enhance physical fitness, improve immunity, and have a significant effect on enhancing resistance to infectious diseases, pathogenic microorganisms and parasites, and improving meat quality and yield.
具体实施例specific embodiment
实施例1Example 1
千屈菜又称水枝柳、水柳、对叶莲。千屈菜科千屈菜属。多年生挺水草本植物。株高1米左右,茎四棱形,直立多分枝,叶对生或轮生,披针形。长穗状花序顶生,小花多而密,紫红色,夏秋开花。自然种生长于沼泽地、沟渠边或滩涂上。喜光、湿润、通风良好的环境,耐盐碱,在肥沃、疏松的土壤中生长效果更好。全株可入药,可治痢疾、肠炎等症;另具外伤止血功效。全草含千屈菜甙(Salicarin)、鞣质。灰分中钠为钾的一倍,并含多量铁,胆碱0.026%。鞣质主为没食子酸鞣质,其含量为:根8.5%,茎10.5%,叶12%,花13.7%,种子亦含大量鞣质。花含黄酮类化合物牡荆素(Vitexin)、荭草素(Orientin)、锦葵花甙(Malvin即Malvidin3,5-diglucoside)、矢车菊素半乳糖甙(Cyanidin3-monogalactoside)、没食子酸、并没食子酸(Ellagicacid)和少量绿原酸(Chlorogenicacid)。含牡荆素(vitexin)、荭草素(orientin)、异荭草素(isoorientin,homoorientin)、绿原酸、鞣花酸及没食子酸,尚含有胆碱、鞣质及色素。且含有少量挥发油、果胶、树脂和生物碱。Qianqucai is also known as Water Branch Willow, Water Willow, and Ye Lian. Thyronidaceae Chrysanthemum genus. Perennial emergent herb. The plant height is about 1 meter, the stem is quadrangular, erect and multi-branched, the leaves are opposite or whorled, lanceolate. Long spikes are terminal, with many and dense small flowers, purple-red, blooming in summer and autumn. Natural species grow in swamps, ditches or tidal flats. It likes a sunny, humid and well-ventilated environment, is resistant to salt and alkali, and grows better in fertile and loose soil. The whole plant can be used as medicine to treat diseases such as dysentery and enteritis; it also has the effect of stopping bleeding from trauma. The whole plant contains salicarin and tannins. The sodium in the ash is twice as much as the potassium, and it contains a lot of iron and choline 0.026%. Tannin is mainly gallic acid tannin, its content is: root 8.5%, stem 10.5%, leaf 12%, flower 13.7%, seed also contains a large amount of tannin. Flowers contain flavonoids Vitexin, Orientin, Malvin (Malvidin3, 5-diglucoside), Cyanidin3-monogalactoside, gallic acid, and gallic acid Acid (Ellagicacid) and a small amount of chlorogenic acid (Chlorogenicacid). Contains vitexin, orientin, isoorientin, homoorientin, chlorogenic acid, ellagic acid and gallic acid, and also contains choline, tannins and pigments. And contains a small amount of volatile oil, pectin, resin and alkaloid.
红背菜,又名观音菜、当归菜、红凤菜、观音苋、红背菜、紫背菜。菊科植物。喜欢生长在阴暗潮湿的地方。叶子的底面是绿色,背面是紫红色,称为“红背菜”。它有助于降血脂,降血糖、助消化,化肠气。是一年四季可品尝的野菜。现代医学证明,红背菜不仅含有丰富的具有造血功能的铁元素,而且富含维生素A原、红背菜黄酮类化合物以及作为酶的活化剂锰元素等,长期食用此莱能起到补血、抑制恶性生长细胞、减少血管紫癜等作用,对于需要补血者,肿瘤患者,受盆腔炎、支气管炎、动脉血管硬化困扰的人群等,可起到食疗的辅助作用,同时它还具有抗寄生虫和抗病毒的作用,增强人体的免疫能力。红背菜的茎叶质地柔软嫩滑,食用时具有特殊风味,也因其叶色特别而常作为景观植物使用,并具有较高的药用价值。Red-backed vegetables, also known as Guanyin vegetables, angelica vegetables, red phoenix vegetables, Guanyin amaranth, red-backed vegetables, and purple-backed vegetables. Asteraceae. Likes to grow in dark and humid places. The underside of the leaves is green and the back is purple-red, which is called "red-backed vegetable". It helps to lower blood fat, lower blood sugar, aid digestion, and dispel intestinal gas. It is a wild vegetable that can be tasted all year round. Modern medicine has proved that red cabbage is not only rich in iron elements with hematopoietic function, but also rich in provitamin A, red cabbage flavonoids and manganese as an enzyme activator, etc. Long-term consumption of this cabbage can nourish blood, Inhibiting malignant growth cells, reducing vascular purpura, etc., it can play an auxiliary role in diet therapy for those who need blood supplementation, tumor patients, and people suffering from pelvic inflammatory disease, bronchitis, and arteriosclerosis. Antiviral effect, enhance the body's immunity. The stems and leaves of red cabbage are soft and tender, and have a special flavor when eaten. Because of their special leaf color, they are often used as landscape plants and have high medicinal value.
薯蓣,通称山药。多年生草本植物,茎蔓生,常带紫色,块根圆柱形,叶子对生,卵形或椭圆形,花乳白色,雌雄异株。块根含淀粉和蛋白质。薯蓣-药用部分,种名:薯蓣(yù),拉丁语学名:Dioscorea opposita别名:山药、三角、怀山药、淮山药、药蛋、土薯、山薯、玉延。气味:(根)甘、温、平、无毒。英文名字:nagaimo,yamaimo,Chinese yam,Japanese mountain yam,Korean yam;本草纲目》记载,薯蓣由于唐代宗叫李豫,为避讳而改为薯药,又因为宋英宗叫赵曙,为避讳而改为山药。山药是六味地黄丸的组成药物之一。[1]山药《本草求真》:“入滋阴药中宜生用,入补脾肺药宜炒黄用。”“本属食物,气虽温而却平,为补脾肺之阴。是以能润皮毛,长肌肉,味甘兼咸,又能益肾强阴。”,在实验性关节炎大鼠的研究中,山药水提液能显著抑制Cu2+对γ球蛋白的变性作用,表明具有抗关节炎的作用。山药水提液还可消除尿蛋白,对突变细胞具有抑制产生的作用。补中益气:铁棍山药因富含18种氨基酸和10余种微量元素,及其它矿物质,所以有健脾胃、补肺肾、补中益气、健脾补虚,固肾益精、益心安神等作用,李时珍《本草纲目》中有“健脾补益、滋精固肾、治诸百病,疗五劳七伤”之说。消渴生津:该山药有消渴生之功效:中医治疗虚劳消渴(糖尿病)处方中常有山药单味使用,或与其它药物合用,效果更佳。保健:由于鲜山药富含多种维生素、氨基酸和矿物质,可以防治人体脂质代谢异常,以及动脉硬化,对维护胰岛素正常功能也有一定作用,有增强人体免疫力,益心安神,宁咳定喘,延缓衰老等保健作用。养颜:元代脾胃专家李杲说:“治皮肤干燥以此物润之。“李时珍写到:“山药能润皮毛。“山药对滋养皮肤,健美养颜有独特疗效。Dioscorea, commonly known as yam. Perennial herbaceous plant with vines, often purple, cylindrical root, opposite leaves, ovate or oval, milky white flowers, dioecious. Root tubers contain starch and protein. Dioscorea-medicinal part, species name: Dioscorea (yù), Latin scientific name: Dioscorea opposita Alias: yam, triangle, Huai yam, Huai yam, medicine egg, soil potato, yam, Yuyan. Odor: (root) sweet, warm, flat, non-toxic. English names: nagaimo, yamaimo, Chinese yam, Japanese mountain yam, Korean yam; According to the "Compendium of Materia Medica", yam was changed to yam medicine because the Tang Emperor’s name was Li Yu, and because Song Yingzong’s name was Zhao Shu, it was changed to yam. Yam is one of the components of Liuwei Dihuang Pills. [1] Chinese yam "Materia Medica Seeking Truth": "It is suitable for raw use in nourishing yin medicine, and fried yellow in medicine for nourishing spleen and lung." It can moisturize fur, grow muscles, taste sweet and salty, and can benefit kidney and strengthen yin.” In the study of experimental arthritis rats, yam water extract can significantly inhibit the denaturation effect of Cu2+ on gamma globulin, indicating that Has anti-arthritic effect. The yam water extract can also eliminate urine protein, which can inhibit the production of mutant cells. Invigorate the middle and nourish Qi: Iron stick yam is rich in 18 kinds of amino acids, more than 10 kinds of trace elements, and other minerals, so it has the functions of strengthening the spleen and stomach, nourishing the lungs and kidneys, nourishing the middle and replenishing qi, strengthening the spleen and replenishing deficiency, strengthening the kidney and replenishing essence, It has the functions of benefiting the heart and calming the nerves. In Li Shizhen's "Compendium of Materia Medica", there is a saying that "invigorates the spleen, nourishes essence and strengthens the kidney, cures all kinds of diseases, and treats five labors and seven injuries". Diabetes-promoting body fluid: The yam has the effect of quenching thirst-promoting: Chinese yam is often used alone in prescriptions for treating consumptive thirst (diabetes) or in combination with other drugs, and the effect is better. Health care: Because fresh yam is rich in various vitamins, amino acids and minerals, it can prevent and treat abnormal lipid metabolism and arteriosclerosis in the human body. It also has a certain effect on maintaining the normal function of insulin. It can enhance human immunity, benefit the heart and calm the nerves. Asthma, anti-aging and other health effects. Beauty: Li Gao, a spleen and stomach expert in the Yuan Dynasty, said: "Treat dry skin with this material to moisturize it." Li Shizhen wrote: "Yam can moisturize the fur." Yam has a unique effect on nourishing the skin, strengthening and beautifying the skin.
本发明根据中医扶正袪邪理论,遵循益气健脾、温阳化湿基本法则,其他中药成份的选择过多年验证、记载和试验所得,虽然它们的功效各异,但是每一种中药的选取都不是随意而为,本申请人根据多年的试验所得各成分的配比,并不是将各成分的原料功效简单叠加,因为各种中药原料之间可能存在相生、相须、相畏或相杀等多种作用关系,而本申请人就是根据这种原则相应的选择了上述原料,并且确定了它们之间的最佳配比,因此,本申请具有显著的意义。According to the theory of strengthening the body and eliminating evils in traditional Chinese medicine, the present invention follows the basic principles of nourishing qi and invigorating the spleen, warming the yang and removing dampness, and the selection of other traditional Chinese medicine ingredients has been verified, recorded and tested for many years. It is not arbitrary. The applicant obtained the ratio of each component based on years of experiments, and it is not a simple superposition of the raw material effects of each component, because there may be mutual growth, mutual growth, mutual fear or mutual killing among various Chinese medicine raw materials. etc., and the applicant selected the above-mentioned raw materials according to this principle, and determined the optimal ratio between them. Therefore, this application has significant significance.
其他涉及的中药成份是经过多年验证、记载和试验所得,虽然它们的功效各异,但是每一种中药的选取都不是随意而为,篇幅所限,在此不进行穷举;Other Chinese medicine ingredients involved are obtained after years of verification, records and tests. Although their effects are different, the selection of each Chinese medicine is not random, and the space is limited, so it is not exhaustive here;
一种提高免疫力的中草药饲料添加剂,其特征在于,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, characterized in that its composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, 10 parts of Caulis Spatholobus, 10 parts of Pueraria Root, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine , 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponins, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylose Alcohol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4~8份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、麦芽3份、磷酸氢钙1份、呈味肽1份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, the composition and parts by weight are: 10 parts of fennel, 10 parts of red cabbage, 5 parts of yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, and 10 parts of Spatholobus 10 parts of kudzu root, 10 parts of cohosh, 10 parts of peony, 4-8 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, gynostemma 2 parts, 2 parts of poria cocos, 3 parts of malt, 1 part of calcium hydrogen phosphate, 1 part of taste peptide, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, Vitamin C, chromium trichloride, xanthan gum, xylitol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5~10份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5-10 parts of Chinese yam, 15 parts of epimedium, and 10 parts of Jiao Shenqu , 10 parts of Caulis Spatholobus, 10 parts of Pueraria Radix, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice Root, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine 2 parts, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, wood Sugar alcohol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, chicken 10 parts of Rhododendron, 10 parts of Pueraria root, 10 parts of cohosh, 10 parts of peony, 4 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol 1. Mannitol crystallization, the ratio of each component of the additional component is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、石粉5份、碘酸钾1份、L-肉碱5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of table salt, 5 parts of stone powder, 1 part of potassium iodate, 5 parts of L-carnitine, and 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、石粉5~10份、碘酸钾1~5份、L-肉碱5~10份、溶菌酶0.5~8份、核苷酸1~5份、溶葡萄球菌酶1~3份、蛋氨酸1~3份、叶酸1~2份,β-葫萝卜素1~2份、酸化剂1~3份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 5-10 parts of stone powder, 1-5 parts of potassium iodate, L-carnitine 5-10 parts, 0.5-8 parts of lysozyme, 1-5 parts of nucleotides, 1-3 parts of lysostaphin, 1-3 parts of methionine, 1-2 parts of folic acid, 1-2 parts of β-carotene , Acidifier 1 to 3 parts.
一种提高免疫力的中草药饲料添加剂制作的饲料,所述酸化剂为酸化剂为柠檬酸、延胡索酸、丙酸、甲酸或乳酸。A feed made of a Chinese herbal medicine feed additive for improving immunity, wherein the acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
一种提高免疫力的中草药饲料添加剂制作的方法,其特征在于步骤如下:A method for making a Chinese herbal medicine feed additive for improving immunity, characterized in that the steps are as follows:
1)选用市售的超微粉碎机;1) Select a commercially available ultrafine pulverizer for use;
2)根据超微粉碎机的一次吞吐量称取相应量的千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。2) According to the one-time throughput of the ultrafine pulverizer, weigh the corresponding amount of 10-30 parts of Chidren, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-35 parts of epimedium, and 10-20 parts of Jiao Shenqu. 20 parts, 10-20 parts of Mildew Spatholobus, 10-20 parts of kudzu root, 10-15 parts of cohosh, 10-15 parts of peony, 4-8 parts of Jianqu, 4-8 parts of rhubarb, 2-5 parts of magnolia bark, 2-5 parts of Rhizome, 3-10 parts of licorice, 5-8 parts of Scutellaria baicalensis, 5-8 parts of Lonicera vine, 2-5 parts of Gynostemma pentaphyllum, 2-5 parts of Poria cocos, 0.15 parts of soybean isoflavone, 1.5 parts of soybean saponin, additional 10 parts of ingredients, the additional ingredients are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, and mannitol crystals, and the proportioning ratio of each component of the additional ingredients is 0.2:0.2: 0.5:0.3:1:1:1.
步骤一、按上述配比称取上述各成分,即千屈菜、红背菜、山药、淫羊藿、焦神曲、鸡血藤、葛根、升麻、芍药、建曲、大黄、厚朴、贯众、甘草、黄芩、忍冬藤、绞股蓝、茯苓,通过超微粉碎机,粉碎后制成超微粉剂至200目待用;所述千屈菜、红背菜是将干燥后的含水量在9wt%以下的根、茎叶、花,置于炒制锅中于130~150℃炒制10分钟,直至表面发黄为止,即取出备用;Step 1. Weigh the above-mentioned ingredients according to the above-mentioned ratio, that is, quinces, red back vegetables, yam, epimedium, Jiao Shenqu, Caulis Spatholobus, kudzu root, cohosh, peony, Jianqu, rhubarb, Magnolia officinalis, Guanzhong, Radix Glycyrrhizae, Scutellaria baicalensis, Lonicerae vine, Gynostemma pentaphyllum, Poria cocos are made into ultrafine powder to 200 orders after being pulverized by an ultrafine pulverizer; Roots, stems, leaves, and flowers with less than 9 wt% are placed in a frying pan and fried at 130-150°C for 10 minutes until the surface turns yellow, and then taken out for later use;
步骤二、按照配比称取粉剂形状的大豆异黄酮、大豆皂甙以及所述附加成分;Step 2, weighing soybean isoflavones, soybean saponins and the additional components in powder form according to the proportioning ratio;
将上述步骤一、二得到的粉剂混合,然后搅匀、在摄氏60℃下减压干燥、灭菌、包装即得到所述提高免疫力的中草药饲料添加剂。The powders obtained in the above steps 1 and 2 are mixed, then evenly stirred, dried under reduced pressure at 60° C., sterilized, and packaged to obtain the immunity-enhancing Chinese herbal medicine feed additive.
按上述制备方法,每份50克。Prepared as above, 50 grams per serving.
药理实验对比例:1、试验日粮Pharmacological experiment comparative example: 1. Experimental diet
(1)选择a、b、c、d四组乳仔猪全价饲料,其中a为本发明提供的预混料;b、c、d预混料与a预混料不同在于微量元素品种及含量存在差异,b预混料所用的均为甘氨酸系列微量元素,c、d预混料所用的均为无机微量元素。(1) Select a, b, c, d four groups of suckling pig full-price feeds, wherein a is the premix provided by the present invention; b, c, d premix are different from a premix in trace element species and content There are differences, the b premix uses glycine series trace elements, and the c and d premixes use inorganic trace elements.
(2)将上述预混料分别配制得到A、B、C、D四种日粮,其中A为使用本发明提供的预混料配制成的日粮。(2) Four kinds of rations A, B, C, and D were obtained by preparing the above-mentioned premix respectively, wherein A was a ration prepared by using the premix provided by the present invention.
A、B、C、D四组日粮的主要营养水平如下表:The main nutritional levels of the four groups of diets A, B, C, and D are as follows:
表1Table 1
2、仔猪分组与饲养管理2. Piglet grouping and feeding management
试验在P1、P2、P3三个猪场进行,P1猪场仔猪共42头,分为T1、T2两个处理组,每组21头,每处理3个重复,每个自然饲养圈为1个重复,每圈7头。饲养于半密闭式猪舍,分别用上述A、B两种日粮饲养33天。P2猪场仔猪共72头,分为T1、T2两个处理组,每组36头,每处理3个重复,每个重复12头。饲养于半密闭式猪舍,分别用上述A、C两种日粮饲养10天。P3猪场仔猪共96头,分为T1、T2两个处理组,每组48头,每处理3个重复,每个重复16头。饲养于半密闭式猪舍,分别用上述A、D两种日粮饲养14天。仔猪自由采食和饮水,每天清理消毒舍内卫生,冲洗饮水器。按正常免疫程序免疫。每天由专人观察记录试验仔猪采食、生长、腹泻及日常行为等情况。The experiment was carried out in three pig farms P1, P2, and P3. A total of 42 piglets in P1 pig farm were divided into two treatment groups, T1 and T2, with 21 pigs in each group, 3 repetitions in each treatment, and 1 piglet in each natural breeding pen. Repeat, 7 heads per circle. They were raised in a semi-closed piggery, and fed with the above-mentioned A and B diets for 33 days. A total of 72 piglets in the P2 pig farm were divided into two treatment groups, T1 and T2, with 36 pigs in each group, 3 replicates in each treatment, and 12 pigs in each replicate. Raise them in a semi-closed piggery, and feed them with the above-mentioned A and C diets for 10 days. A total of 96 piglets in the P3 pig farm were divided into two treatment groups, T1 and T2, with 48 piglets in each group, and 3 replicates in each treatment, with 16 piglets in each replicate. They were raised in a semi-closed piggery, and fed with the above-mentioned A and D diets for 14 days. The piglets have free access to food and water, clean and disinfect the house every day, and rinse the drinking fountains. Immunization according to the normal immunization program. Special personnel observed and recorded the feed intake, growth, diarrhea and daily behavior of the experimental piglets every day.
3、指标检测3. Index detection
日增重、采食量和料肉比:在试验开始和试验结束时分别于早晨8:00空腹称重;称重的同时进行结料,统计采食量;计算试验期仔猪的平均日增重和料肉比。Daily gain, feed intake and feed-to-meat ratio: Weigh on an empty stomach at 8:00 in the morning at the beginning of the test and at the end of the test respectively; carry out feeding while weighing, and count the feed intake; calculate the average daily gain of piglets during the test period Weight to meat ratio.
4、数据处理4. Data processing
试验数据采用SPSS10.0统计软件进行统计,进行方差分析和Duncan’s多重比较。差异显著水平设定:P<0.05为差异显著,P<0.01为差异极显著。The experimental data were statistically analyzed using SPSS 10.0 statistical software, and the analysis of variance and Duncan's multiple comparisons were performed. Significant difference level setting: P<0.05 means significant difference, P<0.01 means extremely significant difference.
5、结果5. Results
生产性能:P1、P2、P3猪场在仔猪阶段分别饲喂A、B、C、D四种日粮,对仔猪生产性能影响如下表:Production performance: P1, P2, and P3 pig farms are fed with four diets A, B, C, and D respectively at the piglet stage. The impact on piglet performance is as follows:
表2Table 2
表3table 3
表4Table 4
注:同行肩标字母相同者,差异不显著;不同者差异显著(P<0.05)。Note: There is no significant difference between peers with the same shoulder label letters; there is significant difference between different ones (P<0.05).
不同处理组的日增重、采食量、料肉比显示:在仔猪阶段,添加了本发明预混料的日粮A组与饲喂日粮B、C、D组相比,日增重及料肉比均显著改善(P<0.05)。A日粮组与B日粮组相比,日增重可提高14.89%,料肉比可降低13.12%;A日粮组与C日粮组相比,日增重可提高12.10%,料肉比可降低9.02%;A日粮组与D日粮组相比,日增重可提高15%,料肉比可降低10.9%。The daily gain, feed intake, and feed-to-meat ratio of different treatment groups show that: in the piglet stage, the daily gain of the diet A group added with the premix of the present invention is higher than that of the feeding diet B, C, and D groups. And feed to meat ratio were significantly improved (P <0.05). Compared with the diet group B, the daily gain of the diet group A can be increased by 14.89%, and the feed-to-meat ratio can be reduced by 13.12%. Ratio can be reduced by 9.02%; A diet group compared with D diet group, the daily gain can be increased by 15%, feed to meat ratio can be reduced by 10.9%.
经药理试验表明:将其制成动物饲料添加剂服用,代替抗生素和药物的使用,既无任何毒副作用,又可明显提高动物的体质,例如仔猪、鸡鸭等,以较低的投入获取较高的经济效益,还无抗生素和化学药物残留,为减少动物性制品中抗生素残留提供有效途径。Pharmacological tests show that taking it as an animal feed additive instead of antibiotics and drugs has no toxic and side effects, and can obviously improve the physique of animals, such as piglets, chickens and ducks, etc., with a lower investment to obtain higher The economic benefits, and no antibiotic and chemical drug residues, provide an effective way to reduce antibiotic residues in animal products.
该产品的原料均充分利用人工种植的资源,其原料资源充足有保证,生产成本低、效率高、经济效益、社会效益显著。The raw materials of this product are all made of artificially planted resources, the raw material resources are sufficient and guaranteed, the production cost is low, the efficiency is high, and the economic and social benefits are remarkable.
实施例2Example 2
一种提高免疫力的中草药饲料添加剂,其特征在于,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, characterized in that its composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, 10 parts of Caulis Spatholobus, 10 parts of Pueraria Root, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine , 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponins, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylose Alcohol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4~8份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、麦芽3份、磷酸氢钙1份、呈味肽1份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, the composition and parts by weight are: 10 parts of fennel, 10 parts of red cabbage, 5 parts of yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, and 10 parts of Spatholobus 10 parts of kudzu root, 10 parts of cohosh, 10 parts of peony, 4-8 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, gynostemma 2 parts, 2 parts of poria cocos, 3 parts of malt, 1 part of calcium hydrogen phosphate, 1 part of taste peptide, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, Vitamin C, chromium trichloride, xanthan gum, xylitol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5~10份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5-10 parts of Chinese yam, 15 parts of epimedium, and 10 parts of Jiao Shenqu , 10 parts of Caulis Spatholobus, 10 parts of Pueraria Radix, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice Root, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine 2 parts, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, wood Sugar alcohol and mannitol are crystallized, and the ratio of each component of the additional ingredients is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, chicken 10 parts of Rhododendron, 10 parts of Pueraria root, 10 parts of cohosh, 10 parts of peony, 4 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol 1. Mannitol crystallization, the ratio of each component of the additional component is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、石粉5份、碘酸钾1份、L-肉碱5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of table salt, 5 parts of stone powder, 1 part of potassium iodate, 5 parts of L-carnitine, and 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、石粉5~10份、碘酸钾1~5份、L-肉碱5~10份、溶菌酶0.5~8份、核苷酸1~5份、溶葡萄球菌酶1~3份、蛋氨酸1~3份、叶酸1~2份,β-葫萝卜素1~2份、酸化剂1~3份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 5-10 parts of stone powder, 1-5 parts of potassium iodate, L-carnitine 5-10 parts, 0.5-8 parts of lysozyme, 1-5 parts of nucleotides, 1-3 parts of lysostaphin, 1-3 parts of methionine, 1-2 parts of folic acid, 1-2 parts of β-carotene , Acidifier 1 to 3 parts.
一种提高免疫力的中草药饲料添加剂制作的饲料,所述酸化剂为酸化剂为柠檬酸、延胡索酸、丙酸、甲酸或乳酸。A feed made of a Chinese herbal medicine feed additive for improving immunity, wherein the acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
一种提高免疫力的中草药饲料添加剂制作的方法,其特征在于步骤如下:A method for making a Chinese herbal medicine feed additive for improving immunity, characterized in that the steps are as follows:
1)选用市售的超微粉碎机;1) Select a commercially available ultrafine pulverizer for use;
2)根据超微粉碎机的一次吞吐量称取相应量的千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。2) According to the one-time throughput of the ultrafine pulverizer, weigh the corresponding amount of 10-30 parts of Chidren, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-35 parts of epimedium, and 10-20 parts of Jiao Shenqu. 20 parts, 10-20 parts of Mildew Spatholobus, 10-20 parts of kudzu root, 10-15 parts of cohosh, 10-15 parts of peony, 4-8 parts of Jianqu, 4-8 parts of rhubarb, 2-5 parts of magnolia bark, 2-5 parts of Rhizome, 3-10 parts of licorice, 5-8 parts of Scutellaria baicalensis, 5-8 parts of Lonicera vine, 2-5 parts of Gynostemma pentaphyllum, 2-5 parts of Poria cocos, 0.15 parts of soybean isoflavone, 1.5 parts of soybean saponin, additional 10 parts of ingredients, the additional ingredients are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, and mannitol crystals, and the proportioning ratio of each component of the additional ingredients is 0.2:0.2: 0.5:0.3:1:1:1.
步骤一、按上述配比称取上述各成分,即千屈菜、红背菜、山药、淫羊藿、焦神曲、鸡血藤、葛根、升麻、芍药、建曲、大黄、厚朴、贯众、甘草、黄芩、忍冬藤、绞股蓝、茯苓,通过超微粉碎机,粉碎后制成超微粉剂至200目待用;所述千屈菜、红背菜是将干燥后的含水量在9wt%以下的根、茎叶、花,置于炒制锅中于130~150℃炒制10分钟,直至表面发黄为止,即取出备用;Step 1. Weigh the above-mentioned ingredients according to the above-mentioned ratio, that is, quinces, red back vegetables, yam, epimedium, Jiao Shenqu, Caulis Spatholobus, kudzu root, cohosh, peony, Jianqu, rhubarb, Magnolia officinalis, Guanzhong, Radix Glycyrrhizae, Scutellaria baicalensis, Lonicerae vine, Gynostemma pentaphyllum, Poria cocos are made into ultrafine powder to 200 orders after being pulverized by an ultrafine pulverizer; Roots, stems, leaves, and flowers with less than 9 wt% are placed in a frying pan and fried at 130-150°C for 10 minutes until the surface turns yellow, and then taken out for later use;
步骤二、按照配比称取粉剂形状的大豆异黄酮、大豆皂甙以及所述附加成分;Step 2, weighing soybean isoflavones, soybean saponins and the additional components in powder form according to the proportioning ratio;
将上述步骤一、二得到的粉剂混合,然后搅匀、在摄氏60℃下减压干燥、灭菌、包装即得到所述提高免疫力的中草药饲料添加剂。The powders obtained in the above steps 1 and 2 are mixed, then evenly stirred, dried under reduced pressure at 60° C., sterilized, and packaged to obtain the immunity-enhancing Chinese herbal medicine feed additive.
按上述制备方法,每份50克。Prepared as above, 50 grams per serving.
将本发明实施例2中的添加剂产品与常规饲料添加剂(本实验选用豫晨化工饲料添加剂厂的添加剂)进行对比试验,试验安排具体如下:The additive product in the embodiment of the present invention 2 and conventional feed additive (this experiment selects the additive of Yuchen Chemical Feed Additive Factory) are carried out comparative test, and test arrangement is specifically as follows:
材料与方法Materials and Methods
1、试验动物1. Experimental animals
选用体重为9kg(±0.5kg)杜×长×大三元杂交商品猪。Commercial pigs with a body weight of 9kg (±0.5kg) Du×Chang×Da Sanyuan were selected.
试验日期、地点Test date and place
2012年1月2日至1月27日于山东某合作猪场。From January 2 to January 27, 2012 in a cooperative pig farm in Shandong.
2、试验设计及日粮2. Experimental design and diet
本试验采用单因子设计,将60头体重9kg(±0.5kg)杜×长×大三元杂交商品猪随机分为2个处理组,每个处理组3个重复,每个重复10头猪。对照组饲喂豫晨化工饲料添加剂厂的添加剂、试验组饲喂实施例1产品持续25天。In this experiment, a single factor design was adopted, and 60 commercial pigs weighing 9kg (±0.5kg) Du × Chang × Da Sanyuan were randomly divided into 2 treatment groups, each treatment group had 3 replicates, and each replicate had 10 pigs. The control group was fed with additives from Yuchen Chemical Feed Additive Factory, and the test group was fed with the product of Example 1 for 25 days.
3、饲养管理3. Feeding management
按照该猪场正常日程进行投料、加水、加药、防疫等饲养管理。Feeding, watering, dosing, and epidemic prevention are carried out according to the normal schedule of the pig farm.
4、测定指标4. Measuring indicators
测定腹泻率、死亡率、日增重以及料肉比指标。Determination of diarrhea rate, mortality rate, daily gain and feed-to-meat ratio indicators.
5、试验结果5. Test results
试验结果见下表1:The test results are shown in Table 1 below:
表5table 5
料肉比1.45±0.061.36±0.04Feed to meat ratio 1.45±0.061.36±0.04
可见,腹泻病发生率下降了2.85%;死亡率试验组比对照组下降了0.9%;日增重试验组比对照组提高了45g;料肉比试验组比对照组降低了0.09。It can be seen that the incidence of diarrheal diseases has decreased by 2.85%; the mortality rate of the test group has decreased by 0.9% compared with the control group; the daily gain of the test group has increased by 45g compared with the control group;
经药理试验表明:将其制成动物饲料添加剂服用,代替抗生素和药物的使用,既无任何毒副作用,又可明显提高动物的体质,例如仔猪、鸡鸭等,以较低的投入获取较高的经济效益,还无抗生素和化学药物残留,为减少动物性制品中抗生素残留提供有效途径。Pharmacological tests show that taking it as an animal feed additive instead of antibiotics and drugs has no toxic and side effects, and can obviously improve the physique of animals, such as piglets, chickens and ducks, etc., with a lower investment to obtain higher The economic benefits, and no antibiotic and chemical drug residues, provide an effective way to reduce antibiotic residues in animal products.
该产品的原料均充分利用人工种植的资源,其原料资源充足有保证,生产成本低、效率高、经济效益、社会效益显著。The raw materials of this product are all made of artificially planted resources, the raw material resources are sufficient and guaranteed, the production cost is low, the efficiency is high, and the economic and social benefits are remarkable.
实施例3Example 3
一种提高免疫力的中草药饲料添加剂,其特征在于,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, characterized in that its composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, 10 parts of Caulis Spatholobus, 10 parts of Pueraria Root, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine , 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponins, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylose Alcohol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4~8份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、麦芽3份、磷酸氢钙1份、呈味肽1份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。A Chinese herbal medicine feed additive for improving immunity, the composition and parts by weight are: 10 parts of fennel, 10 parts of red cabbage, 5 parts of yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, and 10 parts of Spatholobus 10 parts of kudzu root, 10 parts of cohosh, 10 parts of peony, 4-8 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, gynostemma 2 parts, 2 parts of poria cocos, 3 parts of malt, 1 part of calcium hydrogen phosphate, 1 part of taste peptide, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, Vitamin C, chromium trichloride, xanthan gum, xylitol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5~10份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5-10 parts of Chinese yam, 15 parts of epimedium, and 10 parts of Jiao Shenqu , 10 parts of Caulis Spatholobus, 10 parts of Pueraria Radix, 10 parts of Cimicifuga, 10 parts of Peony, 4 parts of Jianqu, 4 parts of Rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of Licorice Root, 5 parts of Scutellaria baicalensis, 5 parts of Lonicera vine 2 parts, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, and the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, wood Sugar alcohol and mannitol are crystallized, and the ratio of each component of the additional components is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of salt, 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10份、红背菜10份、山药5份、淫羊藿15份、焦神曲10份、鸡血藤10份、葛根10份、升麻10份、芍药10份、建曲4份、大黄4份、厚朴2份、贯众2份、甘草3份、黄芩5份、忍冬藤5份、绞股蓝2份、茯苓2份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10 parts of fennel, 10 parts of red cabbage, 5 parts of Chinese yam, 15 parts of epimedium, 10 parts of Jiao Shenqu, chicken 10 parts of Rhododendron, 10 parts of Pueraria root, 10 parts of cohosh, 10 parts of peony, 4 parts of Jianqu, 4 parts of rhubarb, 2 parts of Magnolia officinalis, 2 parts of Guanzhong, 3 parts of licorice, 5 parts of skullcap, 5 parts of honeysuckle, 2 parts of Gynostemma pentaphyllum, 2 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol 1. Mannitol crystallization, the ratio of each component of the additional component is 0.2:0.2:0.5:0.3:1:1:1;
玉米100份、麦麸50份、棕榈粕30份、鱼粉1份、食盐5份、石粉5份、碘酸钾1份、L-肉碱5份、溶菌酶0.5份。100 parts of corn, 50 parts of wheat bran, 30 parts of palm meal, 1 part of fish meal, 5 parts of table salt, 5 parts of stone powder, 1 part of potassium iodate, 5 parts of L-carnitine, and 0.5 part of lysozyme.
一种提高免疫力的中草药饲料添加剂制作的饲料,其组成成分以及重量份数为:千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1;A feed made from a Chinese herbal medicine feed additive for improving immunity. The composition and parts by weight are as follows: 10-30 parts of fennel, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, and 15-35 parts of epimedium 10-20 parts of Jiao Shenqu, 10-20 parts of Spatholobus Spatholobus, 10-20 parts of Pueraria Root, 10-15 parts of Cimicifuga, 10-15 parts of Peony, 4-8 parts of Jianqu, 4-8 parts of Rhubarb, thick 2 to 5 parts of Poria, 2 to 5 parts of Guanzhong, 3 to 10 parts of licorice, 5 to 8 parts of Scutellaria baicalensis, 5 to 8 parts of honeysuckle, 2 to 5 parts of Gynostemma pentaphyllum, 2 to 5 parts of Poria cocos, 0.15 parts of soybean isoflavones, 1.5 parts of soybean saponin, 10 parts of additional components, the additional components are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, mannitol crystals, each component of the additional components is distributed The ratio is 0.2:0.2:0.5:0.3:1:1:1;
玉米100~300份、麦麸50~150份、棕榈粕30~50份、鱼粉1~50份、食盐5~10份、石粉5~10份、碘酸钾1~5份、L-肉碱5~10份、溶菌酶0.5~8份、核苷酸1~5份、溶葡萄球菌酶1~3份、蛋氨酸1~3份、叶酸1~2份,β-葫萝卜素1~2份、酸化剂1~3份。100-300 parts of corn, 50-150 parts of wheat bran, 30-50 parts of palm meal, 1-50 parts of fish meal, 5-10 parts of table salt, 5-10 parts of stone powder, 1-5 parts of potassium iodate, L-carnitine 5-10 parts, 0.5-8 parts of lysozyme, 1-5 parts of nucleotides, 1-3 parts of lysostaphin, 1-3 parts of methionine, 1-2 parts of folic acid, 1-2 parts of β-carotene , Acidifier 1 to 3 parts.
一种提高免疫力的中草药饲料添加剂制作的饲料,所述酸化剂为酸化剂为柠檬酸、延胡索酸、丙酸、甲酸或乳酸。A feed made of a Chinese herbal medicine feed additive for improving immunity, wherein the acidulant is citric acid, fumaric acid, propionic acid, formic acid or lactic acid.
一种提高免疫力的中草药饲料添加剂制作的方法,其特征在于步骤如下:A method for making a Chinese herbal medicine feed additive for improving immunity, characterized in that the steps are as follows:
1)选用市售的超微粉碎机;1) Select a commercially available ultrafine pulverizer for use;
2)根据超微粉碎机的一次吞吐量称取相应量的千屈菜10~30份、红背菜10~20份、山药5~10份、淫羊藿15~35份、焦神曲10~20份、鸡血藤10~20份、葛根10~20份、升麻10~15份、芍药10~15份、建曲4~8份、大黄4~8份、厚朴2~5份、贯众2~5份、甘草3~10份、黄芩5~8份、忍冬藤5~8份、绞股蓝2~5份、茯苓2~5份、大豆异黄酮0.15份、大豆皂甙1.5份、附加成分10份,所述附加成分是维生素A、维生素B、维生素C、三氯化铬、黄元胶、木糖醇、甘露醇结晶,所述附加成分的各组成部分配比为0.2∶0.2∶0.5∶0.3∶1∶1∶1。2) According to the one-time throughput of the ultrafine pulverizer, weigh the corresponding amount of 10-30 parts of Chidren, 10-20 parts of red cabbage, 5-10 parts of Chinese yam, 15-35 parts of epimedium, and 10-20 parts of Jiao Shenqu. 20 parts, 10-20 parts of Mildew Spatholobus, 10-20 parts of kudzu root, 10-15 parts of cohosh, 10-15 parts of peony, 4-8 parts of Jianqu, 4-8 parts of rhubarb, 2-5 parts of magnolia bark, 2-5 parts of Rhizome, 3-10 parts of licorice, 5-8 parts of Scutellaria baicalensis, 5-8 parts of Lonicera vine, 2-5 parts of Gynostemma pentaphyllum, 2-5 parts of Poria cocos, 0.15 parts of soybean isoflavone, 1.5 parts of soybean saponin, additional 10 parts of ingredients, the additional ingredients are vitamin A, vitamin B, vitamin C, chromium trichloride, xanthan gum, xylitol, and mannitol crystals, and the proportioning ratio of each component of the additional ingredients is 0.2:0.2: 0.5:0.3:1:1:1.
步骤一、按上述配比称取上述各成分,即千屈菜、红背菜、山药、淫羊藿、焦神曲、鸡血藤、葛根、升麻、芍药、建曲、大黄、厚朴、贯众、甘草、黄芩、忍冬藤、绞股蓝、茯苓,通过超微粉碎机,粉碎后制成超微粉剂至200目待用;所述千屈菜、红背菜是将干燥后的含水量在9wt%以下的根、茎叶、花,置于炒制锅中于130~150℃炒制10分钟,直至表面发黄为止,即取出备用;Step 1. Weigh the above-mentioned ingredients according to the above-mentioned ratio, that is, quinces, red back vegetables, yam, epimedium, Jiao Shenqu, Caulis Spatholobus, kudzu root, cohosh, peony, Jianqu, rhubarb, Magnolia officinalis, Guanzhong, Radix Glycyrrhizae, Scutellaria baicalensis, Lonicerae vine, Gynostemma pentaphyllum, Poria cocos are made into ultrafine powder to 200 orders after being pulverized by an ultrafine pulverizer; Roots, stems, leaves, and flowers with less than 9 wt% are placed in a frying pan and fried at 130-150°C for 10 minutes until the surface turns yellow, and then taken out for later use;
步骤二、按照配比称取粉剂形状的大豆异黄酮、大豆皂甙以及所述附加成分;Step 2, weighing soybean isoflavones, soybean saponins and the additional components in powder form according to the proportioning ratio;
将上述步骤一、二得到的粉剂混合,然后搅匀、在摄氏60℃下减压干燥、灭菌、包装即得到所述提高免疫力的中草药饲料添加剂。The powders obtained in the above steps 1 and 2 are mixed, then evenly stirred, dried under reduced pressure at 60° C., sterilized, and packaged to obtain the immunity-enhancing Chinese herbal medicine feed additive.
按上述制备方法,每份50克。Prepared as above, 50 grams per serving.
将本发明实施例3中的添加剂产品与常规饲料添加剂(本实验选用豫晨化工饲料添加剂厂的添加剂)进行对比试验,试验安排具体如下:The additive product in the embodiment of the present invention 3 and conventional feed additive (this experiment selects the additive of Yuchen Chemical Feed Additive Factory) are carried out comparative test, and test arrangement is specifically as follows:
材料与方法Materials and Methods
1、试验动物1. Experimental animals
选用体重为9kg(±0.5kg)杜×长×大三元杂交商品猪。Commercial pigs with a body weight of 9kg (±0.5kg) Du×Chang×Da Sanyuan were selected.
试验日期、地点Test date and place
2012年1月2日至1月27日于山东省某合作猪场。From January 2 to January 27, 2012 in a cooperative pig farm in Shandong Province.
2、试验设计及日粮2. Experimental design and diet
本试验采用单因子设计,将60头体重9kg(±0.5kg)杜×长×大三元杂交商品猪随机分为2个处理组,每个处理组3个重复,每个重复10头猪。对照组饲喂豫晨化工饲料添加剂厂的添加剂、试验组饲喂实施例1产品持续25天。In this experiment, a single factor design was adopted, and 60 commercial pigs weighing 9kg (±0.5kg) Du × Chang × Da Sanyuan were randomly divided into 2 treatment groups, each treatment group had 3 replicates, and each replicate had 10 pigs. The control group was fed with additives from Yuchen Chemical Feed Additive Factory, and the test group was fed with the product of Example 1 for 25 days.
3、饲养管理3. Feeding management
按照该猪场正常日程进行投料、加水、加药、防疫等饲养管理。Feeding, watering, dosing, and epidemic prevention are carried out according to the normal schedule of the pig farm.
4、测定指标4. Measuring indicators
测定腹泻率、死亡率、日增重以及料肉比指标。Determination of diarrhea rate, mortality rate, daily gain and feed-to-meat ratio indicators.
5、试验结果5. Test results
试验结果见下表1:The test results are shown in Table 1 below:
表6Table 6
料肉比1.45±0.061.36±0.04Feed to meat ratio 1.45±0.061.36±0.04
可见,腹泻病发生率下降了2.85%;死亡率试验组比对照组下降了0.9%;日增重试验组比对照组提高了45g;料肉比试验组比对照组降低了0.09。It can be seen that the incidence of diarrheal diseases has decreased by 2.85%; the mortality rate of the test group has decreased by 0.9% compared with the control group; the daily gain of the test group has increased by 45g compared with the control group;
经药理试验表明:将其制成动物饲料添加剂服用,代替抗生素和药物的使用,既无任何毒副作用,又可明显提高动物的体质,例如仔猪、鸡鸭等,以较低的投入获取较高的经济效益,还无抗生素和化学药物残留,为减少动物性制品中抗生素残留提供有效途径。Pharmacological tests show that taking it as an animal feed additive instead of antibiotics and drugs has no toxic and side effects, and can obviously improve the physique of animals, such as piglets, chickens and ducks, etc., with a lower investment to obtain higher The economic benefits, and no antibiotic and chemical drug residues, provide an effective way to reduce antibiotic residues in animal products.
在此说明的是实施例中涉及的数值范围均是经过多次实验所得,每一个点都可以实现,不局限在端点或者终点,篇幅所限,在此不进行一一列举。What is explained here is that the numerical ranges involved in the examples are all obtained through multiple experiments, and each point can be realized, not limited to the end point or end point, due to space limitations, and will not be listed here.
最后应说明的是:以上实施例仅用以说明本发明的技术方案,而非对其限制;尽管参照前述实施例对本发明进行了详细的说明,本领域的普通技术人员应当理解:其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换;而这些修改或者替换,并不使相应技术方案的本质脱离本发明各实施例技术方案的精神和范围。Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that: it can still be Modifications are made to the technical solutions described in the foregoing embodiments, or equivalent replacements are made to some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the various embodiments of the present invention.
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CN112352876A (en) * | 2020-11-12 | 2021-02-12 | 重庆市六九畜牧科技股份有限公司 | Antibiotic-free breeding feed additive containing genistein |
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