CN102631661B - Compound natural plant extract with hair renewal function, preparation method and applications thereof - Google Patents
Compound natural plant extract with hair renewal function, preparation method and applications thereof Download PDFInfo
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Abstract
The invention discloses a compound natural plant extract with hair renewal function, a preparation method and applications of the compound natural plant extract. The compound natural plant extract with hair renewal function is prepared from 50-100 parts of Polygonum Multiflorum, 45-90 parts of Radix Astragali, 20-50 parts of Radix Salviae Miltiorrhizae, 10-30 parts of Herba Ecliptae, 5-25 parts of Gastrodia Elata, 5-20 parts of Rhizoma Zingiberis, 5-10 parts of ginseng and 3-5 parts of Cordyceps Sinensis. The compound natural plant extract is obtained by extracting with ultrasonic wave technology, and filtering extracting solution with a micro-filtration film, and the compound natural plant extract can not cause anaphylactic reaction and toxic and side effects after being used for washing hairs. In addition, the ultrasonic wave is used for extracting, so that the extracting time is shortened, the damage to the effective contents caused by high-temperature heating can be avoided; the impurities in the extracting solution can be removed largely after the extracting solution is filtered by the micro-filtration film, and the active ingredients can be maintained, so that the obtained compound natural plant extract has obvious effect on treating alopecia.
Description
Technical field
The invention belongs to vegetable Chinese herbal medicine field and daily cosmetics technical field, particularly a kind of have educate the compound natural plant extract and preparation method thereof and application of sending out function.
Background technology
Modern society, because people's work, life stress are large, psychentonia, makes a lot of people all occur alopecia alopecia phenomenon in various degree.Daily life and environment, as hair is dyed, scalds, blows, drawn, also have the external environment of contact every day in addition, as ultraviolet, dry weather etc., can make hair become short-tempered, fragility, and frangibility even also can be brought the injuries such as withered bifurcated.These inherences and external factor have directly affected the health of scalp hair follicle cell, the speed and the quantity that reduce new natural on-off cycles of hair growth can shorten growth cycle of hair simultaneously, make hair not yet completely grow up and enter resting stage, accelerate coming off of hair, make hair structure present relaxed state.
Have on the market a lot of protecting and caring hair products, these product great majority have added some functional chemical compositions, and the effect after using is general, and long-time use also can bring certain side effect to physical function; Educating of some pure Chinese medicine extraction sent out product because formula collocation is unreasonable, after consumer is used, effect is also undesirable, and product great majority are on the market to prepare with traditional extracting method, the product residual micromolecular Chinese medicine residue of meeting and dust, make product colour be dark-brown, life-time service can run counter to desire on the contrary, stops up hair follicle, affects the metabolism of scalp.
Summary of the invention
Primary and foremost purpose of the present invention is to overcome above-mentioned the deficiencies in the prior art, and a kind of compound natural plant extract of educating a function that has is provided.This compound natural plant extract is applicable to various alopecias, after use, without anaphylaxis, has no side effect, and medicine can infiltrate rapidly skin, improves scalp microcirculation, and nutrition hair follicle cell activates the object that hair follicle reaches hair growth promoting; The phenomenons such as it can also have to impaired hair maintenance effect, correct scared hot-tempered, withered, jag have good improvement.
Another object of the present invention adopts advanced ultrasonic wave extraction and membrane microfiltration technology, and rapid-action, good effect, few, the stay-in-grade a kind of preparation method of educating the compound natural plant extract of sending out function that has of impurity are provided.
A further object of the present invention is to provide described having to educate the application of the compound natural plant extract of sending out function.
Object of the present invention is achieved through the following technical solutions: a kind of have educate the compound natural plant extract of sending out function, by preparing by the Chinese crude drug of mass parts below:
Described have a compound natural plant extract of educating outbreak use, preferably by preparing by the Chinese crude drug of mass parts below:
Above-mentioned all not restrictions of extracting method, leaching process with the compound natural plant extract of educating outbreak use.For example can adopt solvent extraction method, solvent is water, ultrasonic extraction, supercritical extraction etc.;
The described preparation method with the compound natural plant extract of educating outbreak use, preferably extracts by ultrasonic technique and micro-filtration membrane isolation technics is filtered, and comprises following steps:
(1) 50～100 mass parts Radix Polygoni Multiflori, 45～90 mass parts Radixs Astragali, 20～50 mass parts Radix Salviae Miltiorrhizaes, 10～30 mass parts Herba Ecliptaes, 5～25 mass parts Rhizoma Gastrodiaes, 5～20 mass parts Rhizoma Zingiberiss, 5～10 mass parts Radix Ginsengs and 3～5 mass parts Cordyceps are dried, are pulverized and sieved, obtain coarse powder;
(2) in the coarse powder obtaining in step (1), add ethanol water, stir, dipping;
(3) coarse powder/ethanol water that step (2) obtains extracts under ul-trasonic irradiation; Wherein, ultrasonic frequency is 20kHz, extracts 30～50 ℃ of temperature, extraction time 30～50min;
(4) extracting solution step (3) being obtained carries out solid-liquid separation; The liquid filtering obtaining after separation;
(5) filtering residue step (4) separation being obtained carries out repetitive operation by the condition of step (2)～(4);
(6) liquid step (4) and (5) being obtained merges, and is concentrated into relative density and is about 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use;
The degree of the pulverizing described in step (1) is to cross 10 mesh sieves;
It is 60～80% that the concentration of the ethanol water described in step (2) is preferably percent by volume; More preferably percent by volume 70%;
The consumption of the ethanol water described in step (2) is preferably pressed solid-liquid ratio 1g:(7～20) ml calculating; More preferably by material flowing fluid ratio 1g:10ml, calculate;
The time of the dipping described in step (2) is preferably 1～2h;
Extraction temperature described in step (3) is preferably 40 ℃;
Extraction time described in step (3) is preferably 45min;
The mode of the solid-liquid separation described in step (4) is preferably centrifugal;
Filtration described in step (4) is preferably by being used inorganic ceramic micro-filtration membrane to filter;
The aperture of described inorganic ceramic micro-filtration membrane is preferably 1.0 μ m;
Described have the application of compound natural plant extract in shampoo and/or hair care product of educating outbreak use.
Principle of the present invention:
The principal agent Radix Polygoni Multiflori the liver benefiting that nourishes blood in the present invention formula, controlling nocturnal emission with astringent drugs kidney tonifying, crow must hair color, is tonic medicine, and merit is on the Radix Rehmanniae, all medicines of Radix Asparagi.Modern pharmacological research proves, Radix Polygoni Multiflori has neural and the endocrine effect of regulating, thus can hairy root nourishing, impel hair black pigment to generate, make hair shiny black; Its lecithin being rich in is a kind of good hair conditioner, makes hair be easy to combing.
Invigorating QI to consolidate the body surface resistance of the Radix Astragali and Radix Salviae Miltiorrhizae, one restores menstrual flow and invigorates blood circulation, and pharmacological action proves that two medicines all can prevent cell senescence, all has the effect that improves microcirculation, anticoagulant, and both has good antibacterial activity.Particularly Radix Salviae Miltiorrhizae rich in vitamin E and trace element zinc, copper, ferrum, can promote the melanic growth of hair, also can supplement because of hair defects such as poliosis that trace element zinc, copper, iron deficioncy cause, yellow hair, hair are dry.Add the Rhizoma Zingiberis cold expelling that induces sweat, Rhizoma Gastrodiae endogenous wind stopping relieving convulsion, dispelling wind and removing obstruction in the collateral, Herba Ecliptae nourishing the liver and kidney, further dispels ailment said due to cold or exposure, hair care hair strengthening.And Rhizoma Zingiberis has antiinflammatory anti-allergic effects, it is the key medicine of controlling alopecia and raw beard and hair.
Radix Ginseng can strongly invigorating primordial QI, and multiple arteries and veins is admittedly de-, invigorating the spleen to benefit the lung, and ginsenoside is its main active component, ginsenoside can promote protein synthesis, and the regeneration of Skin Cell is had to very strong activation.Cordyceps invigorating the lung and the kidney, real space between skin and muscles, the cordycepin that it contains and Cordyceps mykol can obviously suppress the release of scalp oils and fats, and antiinflammatory antiallergic antioxidation is remarkable.
The present invention adopts the ultimate principle of ultrasonic wave extraction, the powerful shearing force of utilizing ultrasonic cavitation effect to produce is broken plant cell wall, make cell more easily discharge content, accelerate effective ingredients in plant and leach extraction, hyperacoustic second order effect in addition, as mechanical vibration, emulsifying, spread, smash, chemical effect etc., also can accelerate that wish extracts that the diffusion of composition discharges and fully and solvent, be beneficial to extraction.Ultrasonic wave extraction can shorten the time of extraction and improve extraction ratio, compares with conventional method, and that ultrasonic extraction has is simple to operate, extract that the required time is short, extraction efficiency is high and without advantages such as heating.
Chinese medicine extraction liquid contains a large amount of suspended solid microgranules, crude drug cell fragment and soluble high-molecular material (as starch, phlegmatic temperament, protein etc.), these impurity components in extracting solution can affect stability and the outward appearance of product, and the filter methods such as traditional centrifugalize, flocculation often can not be removed above-mentioned impurity effectively, therefore need to remove the impurity in extract by better method, retain as much as possible effective ingredient.Micro-filtration membrane isolation technics is a kind of novel clarification impurity removing technology, and its main separation mechanism is that sieve aperture is separated, and film can be held back the solute larger than its aperture, colloid and microgranule.Membrane separation technique is compared tool with traditional technology and is had the following advantages: 1. remove impurity is thorough, and product clarity is high, and microfiltration technology can be removed the solids of 0.025 ~ 10 μ m size; 2. loss of effective components is few, product stability is high: Effective Component of Chinese Medicine molecular weight is generally below 1000, therefore microfiltration process is not generally held back effective ingredient, and there is not the conversion of phase in membrane separation technique, do not need heating, operating condition is gentle, needn't add chemical reagent, thus effective ingredient particularly thermal sensitivity composition destroy few; 3. technique is simple, easy to operate, with short production cycle, energy-conservation, is conducive to reduce the cost.
The present invention has following advantage and effect with respect to prior art:
(1) provided by the invention have that to educate the formula of the compound natural plant extract of sending out function reasonably combined according to Traditional Chinese medical theory, there is functions of nourishing hair and growing hair, improve local blood circulation, increase the nutrition supply of hair follicle, reduce sebum secretion, prevention follicular orifice hyperkeratosis, trichogenous effect, simultaneously can be antipruritic, sterilization, increases hair toughness;
(2) extract that the present invention obtains can have good curative effect to various alopecias (nervous alopecia, seborrheic alopecia, alopecia areata, hypotrichosis, after being ill puerperal alopecia etc.); The hair fragility that the present invention causes for injuries such as hair-waving, hair dyeing, daylight ultraviolet is easily broken, and withered short-tempered bifurcated etc. has good nutrition maintenance effect, bright, submissive, tough with rear hair black, and can make hair structure become tight;
(3) the present invention utilizes ultrasonic wave extraction to shorten extraction time, avoids the destruction of high-temperature heating to effective ingredient, improves the extraction ratio of effective ingredient, has overcome the shortcoming existing in Chinese medicine extracting method.Micro-filtration membrane isolation technics is filtered extracting solution, can effectively remove macromole impurity, more retains effective ingredient.Make extract color of the present invention for clarification magma, medicine can infiltrate rapidly scalp.Preparation method of the present invention is simple, greatly saves time and the energy, is conducive to reduce costs.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to this.
Embodiment 1
(1) Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps are handled as follows respectively: dry, by pulverizer, pulverize, cross 10 mesh sieves, obtain coarse powder;
(2) by Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps powder coarse powder in mass ratio 60:50:25:20:15:10:5:3 mix, obtain mixing medical material medicated powder;
(3) in the mixing medical material medicated powder obtaining in step (2), add percent by volume 70% ethanol water, by 1g solid proportioning 10ml 70% ethanol water, calculate; Then stir, dipping 2h;
(4) material liquid mixture step (3) being obtained extracts under ul-trasonic irradiation, and ultrasonic frequency is 20kHz, extracts 40 ℃ of temperature, extraction time 45min;
(5) extracting solution step (4) being obtained carries out centrifugal, and rotating speed is 10000r/min; The liquid passage aperture obtaining after centrifugal is that the inorganic ceramic micro-filtration membrane of 1.0 μ m filters;
(6) filtering residue step (5) separation being obtained carries out repetitive operation by the condition of step (3)～(5);
(7) liquid step (5) and (6) being obtained merges, and filtrate is concentrated into relative density and is about 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
(8) having of being prepared by step (7) educated the compound natural plant extract of outbreak use in the ethanol water 1:17 mixing in mass ratio of percent by volume 55%, obtains Chinese herbal hair nourishing liquid I.
Embodiment 2
(1) with embodiment 1 step (1);
(2) by Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps powder coarse powder in mass ratio 80:80:40:30:25:20:8:3 mix, obtain mixing medical material medicated powder;
(3) in the mixing medical material medicated powder obtaining in step (2), add percent by volume 70% ethanol water, by 1g solid proportioning 10ml 70% ethanol water, calculate; Then stir, dipping 2h;
(4) material liquid mixture step (3) being obtained extracts under ul-trasonic irradiation, and ultrasonic frequency is 20kHz, extracts 40 ℃ of temperature, extraction time 45min;
(5) extracting solution step (4) being obtained carries out centrifugal, and rotating speed is 10000r/min; The liquid passage aperture obtaining after centrifugal is that the inorganic ceramic micro-filtration membrane of 1.0 μ m filters;
(6) filtering residue step (5) separation being obtained carries out repetitive operation by the condition of step (3)～(5);
(7) liquid step (5) and (6) being obtained merges, and filtrate is concentrated into relative density and is about 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
(8) having of being prepared by step (7) educated the compound natural plant extract of outbreak use in the ethanol water 1:17 mixing in mass ratio of percent by volume 55%, obtains Chinese herbal hair nourishing liquid II.
Embodiment 3
(1) with embodiment 1 step (1);
(2) by Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps powder coarse powder in mass ratio 50:90:20:30:5:20:10:5 mix, obtain mixing medical material medicated powder;
(3) in the mixing medical material medicated powder obtaining in step (2), add percent by volume 70% ethanol water, by 1g solid proportioning 7ml 70% ethanol water, calculate; Then stir, dipping 2h;
(4) material liquid mixture step (3) being obtained extracts under ul-trasonic irradiation, and ultrasonic frequency is 20kHz, extracts temperature 45 C, extraction time 40min;
(5) extracting solution step (4) being obtained carries out centrifugal, and rotating speed is 10000r/min; The liquid passage aperture obtaining after centrifugal is that the inorganic ceramic micro-filtration membrane of 1.0 μ m filters;
(6) filtering residue step (5) separation being obtained carries out repetitive operation by the condition of step (3)～(5);
(7) liquid step (5) and (6) being obtained merges, and filtrate is concentrated into relative density and is about 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
(8) having of being prepared by step (7) educated the compound natural plant extract of outbreak use in the ethanol water 1:17 mixing in mass ratio of percent by volume 55%, obtains Chinese herbal hair nourishing liquid III.
Embodiment 4
(1) with embodiment 1 step (1);
(2) by Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps powder coarse powder in mass ratio 100:45:50:10:5:5:10:4 mix, obtain mixing medical material medicated powder;
(3) in the mixing medical material medicated powder obtaining in step (2), add percent by volume 70% ethanol water, by 1g solid proportioning 20ml 70% ethanol water, calculate; Then stir, dipping 2h;
(4) material liquid mixture step (3) being obtained extracts under ul-trasonic irradiation, and ultrasonic frequency is 20kHz, extracts 40 ℃ of temperature, extraction time 45min;
(5) extracting solution step (4) being obtained carries out centrifugal, and rotating speed is 10000r/min; The liquid passage aperture obtaining after centrifugal is that the inorganic ceramic micro-filtration membrane of 1.0 μ m filters;
(6) filtering residue step (5) separation being obtained carries out repetitive operation by the condition of step (3)～(5);
(7) liquid step (5) and (6) being obtained merges, and filtrate is concentrated into relative density and is about 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
(8) having of being prepared by step (7) educated the compound natural plant extract of outbreak use in the ethanol water 1:17 mixing in mass ratio of percent by volume 55%, obtains Chinese herbal hair nourishing liquid IV.
Comparative example 1
(1) with embodiment 1 step (1);
(2) with embodiment 1 step (2);
(3) in the mixing medical material medicated powder obtaining in step (2), add water, by 1g solid proportioning 20ml water, calculate; Then stir; Soak 30min;
(4) boil and extract 90min, take out extracting solution, filter, obtain filtrate;
(5) add water in extraction pot, repeating step (4), obtains filtrate again;
(6) filtrate step (4) and (5) being obtained merges, concentrated, is cooled to 40 ℃; Then under stirring, add percent by volume 95% ethanol, make the extracting solution finally obtaining for containing the mixed liquor that alcohol amount is 40%;
(7) airtight placement 12h, now precipitation is completely;
(8) remove by filter precipitation, reclaim ethanol, obtain concentrated solution;
(9) use 500 order filter-cloth filtering concentrated solutions, obtain Chinese herbal hair nourishing liquid V.
Effect embodiment
The Chinese herbal hair nourishing liquid that above embodiment is prepared carries out activity test, with observing effect.
The experiment number of every kind of hair nourishing liquid is 20 people, male 10 examples, and female's 10 examples, all have pathologic baldness shape, the age: 18～45 years old.
Using method: external, every day 1 time, each 2-5ml, is applied to the soft extremely heating in alopecia position by this product, and using continuously 1 month is 1 course for the treatment of, and 6 courses for the treatment of are as observation of curative effect.
Experimental result:
Criterion of therapeutical effect is divided into: (1) is effective: without obviously alopecia, have a large amount of new hairs to generate; (2) effective: alopecia is controlled, there is a small amount of new hair to generate; (3) invalid: unchanged before and after treatment.
The curative effect of Chinese herbal hair nourishing liquid is as shown in table 1.
Table 1
| Effective | Effectively | Invalid | Total effective rate | |
| Chinese herbal hair nourishing liquid I | 16 | 4 | 0 | 100% |
| Chinese herbal hair nourishing liquid II | 15 | 3 | 2 | 95% |
| Chinese herbal hair nourishing liquid III | 14 | 3 | 3 | 85% |
| Chinese herbal hair nourishing liquid IV | 13 | 4 | 3 | 85% |
| Chinese herbal hair nourishing liquid V | 10 | 2 | 8 | 60% |
Clinical trial process shows, uses Chinese herbal hair nourishing liquid I～IV, and speckle is de-can be grown new in average 25 days with male pattern alopecia; Use Chinese herbal hair nourishing liquid V, speckle is de-just to be grown new with male pattern alopecia average 40.
Known by the above results, the Chinese herbal hair nourishing liquid that the Chinese herbal hair nourishing liquid obtaining by ultrasonic extraction obtains than traditional heating extraction is effective.
Above-described embodiment is preferably embodiment of the present invention; but embodiments of the present invention are not restricted to the described embodiments; other any do not deviate from change, the modification done under spirit of the present invention and principle, substitutes, combination, simplify; all should be equivalent substitute mode, within being included in protection scope of the present invention.
Claims (10)
1. have and educate a compound natural plant extract of sending out function, it is characterized in that by preparing by the Chinese crude drug of mass parts below:
50～100 parts of Radix Polygoni Multiflori
45～90 parts of the Radixs Astragali
20～50 parts of Radix Salviae Miltiorrhizaes
10～30 parts of Herba Ecliptaes
5～25 parts, Rhizoma Gastrodiae
5～20 parts of Rhizoma Zingiberiss
5～10 parts of Radix Ginsengs
3～5 parts of Cordyceps;
Described have educate the compound natural plant extract of sending out function and prepare by the method that comprises following steps:
(1) Radix Polygoni Multiflori, the Radix Astragali, Radix Salviae Miltiorrhizae, Herba Ecliptae, Rhizoma Gastrodiae, Rhizoma Zingiberis, Radix Ginseng and Cordyceps are dried, are pulverized and sieved, obtain coarse powder;
(2) in the coarse powder obtaining in step (1), add ethanol water, stir, dipping;
(3) coarse powder/ethanol water that step (2) obtains extracts under ul-trasonic irradiation; Wherein, ultrasonic frequency is 20kHz, extracts 30～50 ℃ of temperature, extraction time 30～50min;
(4) extracting solution step (3) being obtained carries out solid-liquid separation; The liquid filtering obtaining after separation;
(5) filtering residue step (4) separation being obtained carries out repetitive operation by the condition of step (2)～(4);
(6) liquid step (4) and (5) being obtained merges, and being concentrated into relative density is 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
According to claim 1 have educate outbreak use compound natural plant extract, it is characterized in that by preparing by the Chinese crude drug of mass parts below:
60～80 parts of Radix Polygoni Multiflori
50～80 parts of the Radixs Astragali
25～40 parts of Radix Salviae Miltiorrhizaes
20～30 parts of Herba Ecliptaes
15～25 parts, Rhizoma Gastrodiae
10～20 parts of Rhizoma Zingiberiss
5～10 parts of Radix Ginsengs
3～5 parts of Cordyceps.
3. claimed in claim 1 have a preparation method of compound natural plant extract of educating outbreak use, it is characterized in that comprising following steps:
(1) 50～100 mass parts Radix Polygoni Multiflori, 45～90 mass parts Radixs Astragali, 20～50 mass parts Radix Salviae Miltiorrhizaes, 10～30 mass parts Herba Ecliptaes, 5～25 mass parts Rhizoma Gastrodiaes, 5～20 mass parts Rhizoma Zingiberiss, 5～10 mass parts Radix Ginsengs and 3～5 mass parts Cordyceps are dried, are pulverized and sieved, obtain coarse powder;
(2) in the coarse powder obtaining in step (1), add ethanol water, stir, dipping;
(3) coarse powder/ethanol water that step (2) obtains extracts under ul-trasonic irradiation; Wherein, ultrasonic frequency is 20kHz, extracts 30～50 ℃ of temperature, extraction time 30～50min;
(4) extracting solution step (3) being obtained carries out solid-liquid separation; The liquid filtering obtaining after separation;
(5) filtering residue step (4) separation being obtained carries out repetitive operation by the condition of step (2)～(4);
(6) liquid step (4) and (5) being obtained merges, and being concentrated into relative density is 1.10～1.13, obtains having the compound natural plant extract of educating outbreak use.
4. the preparation method with the compound natural plant extract of educating outbreak use according to claim 3, is characterized in that: the degree of the pulverizing described in step (1) is for crossing 10 mesh sieves.
5. the preparation method with the compound natural plant extract of educating outbreak use according to claim 3, is characterized in that: the concentration of the ethanol water described in step (2) is percent by volume 60～80%;
The consumption of the ethanol water described in step (2) is pressed solid-liquid ratio 1:(7～20) calculate;
The time of the dipping described in step (2) is 1～2h.
6. the preparation method with the compound natural plant extract of educating outbreak use according to claim 5, is characterized in that: the concentration of the ethanol water described in step (2) is percent by volume 70%;
The consumption of the ethanol water described in step (2) calculates by material flowing fluid ratio 1:10.
7. the preparation method with the compound natural plant extract of educating outbreak use according to claim 3, is characterized in that: the extraction temperature described in step (3) is 40 ℃;
Extraction time described in step (3) is 45min.
8. the preparation method with the compound natural plant extract of educating outbreak use according to claim 3, is characterized in that: the mode of the solid-liquid separation described in step (4) is centrifugal;
Being filtered into by using inorganic ceramic micro-filtration membrane to filter described in step (4).
9. the preparation method with the compound natural plant extract of educating outbreak use according to claim 8, is characterized in that: the aperture of described inorganic ceramic micro-filtration membrane is 1.0 μ m.
10. having described in claim 1 or 2 educated the application of compound natural plant extract in hair care product of outbreak use.
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| CN104222857A (en) * | 2014-08-30 | 2014-12-24 | 孟钧 | Traditional Chinese medicine porridge for treating prematurely grey hair |
| CN105687085A (en) * | 2016-03-10 | 2016-06-22 | 蚌埠团结日用化学有限公司 | Natural plant hair dye and preparation method thereof |
| CN106236633A (en) * | 2016-08-19 | 2016-12-21 | 王婷 | A kind of plant hair conditioner |
| CN108186531A (en) * | 2018-03-09 | 2018-06-22 | 广州市娇兰化妆品有限公司 | A kind of generating hair essence liquid and preparation method and application |
| CN108904771A (en) * | 2018-08-23 | 2018-11-30 | 广州市庚晖精细化工有限公司 | A kind of hair-growing composition containing Co-Q10 |
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| CN1301745C (en) * | 2004-11-26 | 2007-02-28 | 付小珍 | Chinese medicinal liquid for treating alopecia and its production method |
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