CN102488851A - Drug for treating recurrent genital herpes and preparation method thereof - Google Patents
Drug for treating recurrent genital herpes and preparation method thereof Download PDFInfo
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- CN102488851A CN102488851A CN2011104462595A CN201110446259A CN102488851A CN 102488851 A CN102488851 A CN 102488851A CN 2011104462595 A CN2011104462595 A CN 2011104462595A CN 201110446259 A CN201110446259 A CN 201110446259A CN 102488851 A CN102488851 A CN 102488851A
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- 229940079593 drug Drugs 0.000 title claims abstract description 19
- 230000000306 recurrent effect Effects 0.000 title abstract description 7
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a drug for treating recurrent genital herpes and a preparation method thereof. The drug for treating recurrent genital herpes comprises rhizoma atractylodis, fineleaf schizonepeta herb, divaricate saposhnikovia root, isatis root, folium isatidis, poria cocos, coix seed, Chinese yam, bighead atractylodes rhizome, radix pseudostellariae, rheum officinale, baical skullcap root, bark of Chinese corktree, licorice, dahurica angelica root, platycodon root, rehmannia root and cicada slough. The preparation method comprises the following steps of 1, putting the medicinal raw materials into a heating pot, adding water into the heating pot, wherein the weight of the added water is 8 times that of the medicinal raw materials, immersing the medicinal raw materials for 2 hours, boiling for 3 hours, filtering, and collecting the filtrate, 2, adding water into the filter residues until the filter residues are submerged by the water, boiling for 1 hour, filtering, and collecting the filtrate, and 3, merging the filtrate obtained by the step 1 and the step 2, carrying out reduced pressure condensation to obtain extract having a ratio of 1: 1, drying the extract by an oven, crushing the dried extract into fine powder, adding an appropriate amount of dextrin into the fine powder, mixing uniformly to obtain the drug for treating recurrent herpes progenitalis, and packaging by capsules, wherein each 0.5 grams of the drug for treating recurrent herpes progenitalis is put into a 0-type capsule. The drug for treating recurrent herpes progenitalis is suitable for being utilized in an early herpes attack stage, a herpes attack stage and a herpes recovery stage, has clear curative effects, can produce effects directly and fast, realizes simultaneous treatment of principal and subordinate symptoms, realizes a recurrence rate of 0, is safe and convenient and does not have toxic and side effects.
Description
Technical field
The invention belongs to the medicine of treatment genital herpes, particularly a kind of treatment medicine of genital herpes and preparation method thereof that shows effect repeatedly.
Background technology
The genital herpes traditional Chinese medical science thinks and belongs to dampness-heat of the liver, due to the stagnation of QI due to depression of the liver blood stasis, and the Chinese medicine of the genital herpes that traditional treatment shows effect repeatedly, effect is not fine.
The western medicine genital herpes still lacks specific medicament and method at present, especially to the genital herpes of recurrent, and stubborn problem especially.The Center for Disease Control (CDC) and the treatment genital herpes scheme that China formulated are all recommended acycloguanosine; It is acyclovir (acyclic bird former times; ACV) be converted into the triphosphoric acid chemical compound in vivo, the DNA polymerization of disturbing HSV is arranged, can suppress duplicating of viral DNA; Be current treatment pudendum herpes than active drug, use as early as possible and can improve symptom.This agent also can be used for preventing recurrence.Need prolong administration time when sending out genital herpes more repeatedly, the someone reports oral ACV200mg, and every day 3 times, continuous application 6 ~ 12 months can have 50% ~ 70% patient to control recurrence fully, and therapeutic process is long, and effect neither be desirable especially.
Summary of the invention
One of the object of the invention has provided show effect the repeatedly medicine of genital herpes of a kind of treatment, determined curative effect, effect directly, onset is rapid, treating both the principal and secondary aspects of a disease does not recur, safe ready is without any side effects.
Another purpose of the present invention has provided show effect the repeatedly method for preparing of medicine of genital herpes of a kind of above-mentioned treatment.
The objective of the invention is to realize through following technical proposal:
Show effect the repeatedly medicine of genital herpes of a kind of treatment comprises Chinese herbal medicine extract, and it is characterized in that: said Chinese medicine extract is processed by weight according to following bulk drugs:
10 parts of Rhizoma Atractylodis 10-15 parts, Herba Schizonepetae 8-12 part, windproof 8-12 part, Radix Isatidis 12-18 part, Folium Isatidis 10-18 part, Poria 8-12 part, Semen Coicis core 20-40 part, Rhizoma Dioscoreae 20-40 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Radix Pseudostellariae 8-12 part, 2 parts of Radix Et Rhizoma Rhei 8-1, Radix Scutellariae 10-12 part, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, Radix Angelicae Dahuricae 10-12 part, Radix Platycodonis 10-12 part, Radix Rehmanniae 10-15 part, Periostracum Cicadae.
Further, said Chinese medicine extract is processed by weight according to following bulk drugs:
12 parts of Rhizoma Atractylodis, 10 parts of Herba Schizonepetae, windproof 10 parts, 15 parts of Radix Isatidis, 15 parts of Folium Isatidiss, 10 parts in Poria, 30 parts of Semen Coicis core, 30 parts of Rhizoma Dioscoreaes, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Pseudostellariaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Scutellariaes, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, 6 parts of the Radixs Angelicae Dahuricae, 6 parts of Radix Platycodoniss, 12 parts in the Radix Rehmanniae, 10 parts of Periostracum Cicadaes.
Further, said agents is granule, tablet, capsule, pill.
Further, also comprise the acyclovir tablet in the said medicine.
Show effect the repeatedly method for preparing of medicine of genital herpes of a kind of treatment, its step is following:
1) takes by weighing raw material according to proportioning, and medicine is removed impurity, clean;
2) said medicine is placed heating kettle, adding simultaneously is the water of 8 times of amounts of drug weight, invades bubble 2 and is as a child boiling 3 hours the back, filters, and collects filtrating;
3) add water logging once more and do not have medicinal residues, boiled one hour, filter, collect filtrating;
4) twice filtrating is merged the extractum that becomes 1:1 with concentrating under reduced pressure, oven dry is ground into fine powder, adds an amount of dextrin, abundant mix homogeneously, and with No. 0 capsule, every 0.5 restrains to pack into and gets final product.
The side separates: use Radix Platycodonis, and the Radix Rehmanniae, Radix Isatidis, Folium Isatidis, Radix Et Rhizoma Rhei, Radix Scutellariae and Cortex Phellodendri all have effects such as clearing away heat-damp and promoting diuresis antiviral; Radix Pseudostellariae, Semen Coicis core, Rhizoma Atractylodis, the Rhizoma Atractylodis Macrocephalae, Rhizoma Dioscoreae, Poria are the strengthening vital QI to eliminate pathogenic factors supplementing QI and nourishing YIN, damp eliminating, spleen invigorating, the QI invigorating medicine, can play the effect of strengthening the body resistance; Herba Schizonepetae, windproof, the Radix Angelicae Dahuricae, Periostracum Cicadae, it is eliminating evil to have a dispelling wind, the effect of antiviral, Radix Glycyrrhizae has the effect with middle detoxifcation.
Beneficial effect of the present invention:
Beneficial effect of the present invention:
Drug regimen of the present invention has heat-clearing and toxic substances removing, the effect of eliminating evil dampness removing, and can increase the immunity of human body, the immunologic function of regulating human body effectively; Resist exopathogen and the effect of getting rid of evils, be applicable to the outbreak early stage of herpes, stage of attack, and convalescent period; Determined curative effect, effect is direct, and onset is rapid, treating both the principal and secondary aspects of a disease; Do not recur, safe ready, without any side effects.
The specific embodiment
Below in conjunction with embodiment summary of the invention of the present invention is done further to describe, following explanation only is exemplary, does not limit protection scope of the present invention.
Embodiment 1
Show effect the repeatedly medicine of genital herpes of a kind of treatment; Comprise Chinese herbal medicine extract, said Chinese medicine extract is processed by weight according to following bulk drugs: 15 parts of Rhizoma Atractylodis, 12 parts of Herba Schizonepetae, windproof 12 parts, 18 parts of Radix Isatidis, 18 parts of Folium Isatidiss, 12 parts in Poria, 40 parts of Semen Coicis core, 40 parts of Rhizoma Dioscoreaes, 12 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Radix Pseudostellariaes, 12 parts of Radix Et Rhizoma Rhei, 12 parts of Radix Scutellariaes, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, 12 parts of the Radixs Angelicae Dahuricae, 12 parts of Radix Platycodoniss, 15 parts in the Radix Rehmanniae, 10 parts of Periostracum Cicadaes.
Show effect the repeatedly method for preparing of genital herpes medicine of a kind of treatment, its step is following:
1) takes by weighing raw material according to proportioning, and medicine is removed impurity, clean;
2) said medicine is placed heating kettle, adding simultaneously is the water of 8 times of amounts of drug weight, invades bubble 2 and is as a child boiling 3 hours the back, filters, and collects filtrating;
3) add water logging once more and do not have medicinal residues, boiled one hour, filter, collect filtrating;
4) twice filtrating is merged the extractum that becomes 1:1 with concentrating under reduced pressure, oven dry is ground into fine powder, adds an amount of dextrin, abundant mix homogeneously, and with No. 0 capsule, every 0.5 restrains to pack into and gets final product.
Usage and dosage of the present invention: Chinese medicine extract is taken 2.0g at every turn, and acyclovir is taken 0.2g at every turn, takes one day twice simultaneously.
Taboo: to any Chinese medicine ingredients in the above-mentioned Chinese medicine with to acyclovir, allergy sufferers is prohibited clothes.
In order to prove that the present invention treats the effect of the genital herpes that shows effect repeatedly; The present invention is with medicine of the present invention and other drug treatment carrying out clinical control; The genital herpes patient that we select 150 examples to show effect repeatedly; Per 50 people are one group, respectively take 3 months, and the A group is for taking the patient of above Chinese medicine extract merely; The B group is for taking the patient of acyclovir slice merely; The C group is taken Chinese medicine of the present invention and acyclovir slice.Curative effect judging standard: recovery from illness: decrustation fully.Produce effects: begin incrustation.
Concrete outcome is following:
See from therapeutic effect, take Chinese medicine of the present invention and acyclovir slice simultaneously after 3 months, to repeatedly the outbreak the genital herpes cure rate can arrive 98%, take separately the invention Chinese medicine after, to repeatedly the outbreak the genital herpes cure rate can arrive 90%.
Embodiment 2
Show effect the repeatedly medicine of genital herpes of a kind of treatment; Comprise Chinese herbal medicine extract, said Chinese medicine extract is processed by weight according to following bulk drugs: 10 parts of Rhizoma Atractylodis, 8 parts of Herba Schizonepetae, windproof 8 parts, 12 parts of Radix Isatidis, 10 parts of Folium Isatidiss, 8 parts in Poria, 20 parts of Semen Coicis core, 20 parts of Rhizoma Dioscoreaes, 8 parts of the Rhizoma Atractylodis Macrocephalaes, 8 parts of Radix Pseudostellariaes, 8 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Scutellariaes, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, 10 parts of the Radixs Angelicae Dahuricae, 10 parts of Radix Platycodoniss, 10 parts in the Radix Rehmanniae, 10 parts of Periostracum Cicadaes.
The direct pulverizing mixing of above-mentioned raw materials medicine is processed tablet or pill by common process.
Method for using: oral every day 2-3 time, at every turn take 2g.
Taboo: to any Chinese medicine ingredients in the above-mentioned Chinese medicine, allergy sufferers is prohibited clothes.
Model case: Tang, the man, 45 years old, be diagnosed as genital herpes before 2 years, have an injection to take medicine and show effect repeatedly, can't effect a radical cure.Health check-up: there are erythema and blister in glans penis and foreskin inboard, general weakness, and affected part pain is unbearably.After taking Chinese herbal medicine extract of the present invention, erythema disappears after 15 days, and not recurrence in 1 year is visited in recovery from illness after 1 month.
Embodiment 3
Show effect the repeatedly medicine of genital herpes of a kind of treatment; Comprise Chinese herbal medicine extract, said Chinese medicine extract is processed by weight according to following bulk drugs: 12 parts of Rhizoma Atractylodis, 10 parts of Herba Schizonepetae, windproof 10 parts, 15 parts of Radix Isatidis, 15 parts of Folium Isatidiss, 10 parts in Poria, 30 parts of Semen Coicis core, 30 parts of Rhizoma Dioscoreaes, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Pseudostellariaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Scutellariaes, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, 6 parts of the Radixs Angelicae Dahuricae, 6 parts of Radix Platycodoniss, 12 parts in the Radix Rehmanniae, 10 parts of Periostracum Cicadaes.
The direct pulverizing mixing of above-mentioned raw materials medicine is processed pill by common process.
Method for using: take 2g oral every day 2-3 time, acyclovir is taken 0.2g at every turn at every turn, takes every day 2-3 time simultaneously.
Taboo: to any Chinese medicine ingredients in the above-mentioned Chinese medicine, allergy sufferers is prohibited clothes.
Model case: the woman, 40 years old, oral acyclovir slice treatment took a turn for the better again after 3 months, but recurrence again after 2-4 month.Health check-up: pudendum has a plurality of blisters, dysuria, and leucorrhea has abnormal flavour.Diagnosis: genital herpes recurrence.Take medicine of the present invention and acyclovir slice and fully recover after 2 months, visited 2 years, do not have recurrence.
Should be appreciated that the above detailed description of technical scheme of the present invention being carried out by preferred embodiment is schematic and nonrestrictive.Those of ordinary skill in the art is reading on the basis of description of the present invention and can make amendment to the technical scheme that each instance is put down in writing, and perhaps part technical characterictic wherein is equal to replacement; And these are revised or replacement, do not make the spirit and the scope of the essence disengaging various embodiments of the present invention technical scheme of relevant art scheme.
Claims (5)
1. the treatment medicine of genital herpes that shows effect repeatedly comprises Chinese herbal medicine extract, and it is characterized in that: said Chinese medicine extract is processed by weight according to following bulk drugs:
10 parts of Rhizoma Atractylodis 10-15 parts, Herba Schizonepetae 8-12 part, windproof 8-12 part, Radix Isatidis 12-18 part, Folium Isatidis 10-18 part, Poria 8-12 part, Semen Coicis core 20-40 part, Rhizoma Dioscoreae 20-40 part, Rhizoma Atractylodis Macrocephalae 8-12 part, Radix Pseudostellariae 8-12 part, 2 parts of Radix Et Rhizoma Rhei 8-1, Radix Scutellariae 10-12 part, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, Radix Angelicae Dahuricae 10-12 part, Radix Platycodonis 10-12 part, Radix Rehmanniae 10-15 part, Periostracum Cicadae.
2. show effect the repeatedly medicine of genital herpes of said treatment according to claim 1, its characteristic exists; Said Chinese medicine extract is processed by weight according to following bulk drugs:
12 parts of Rhizoma Atractylodis, 10 parts of Herba Schizonepetae, windproof 10 parts, 15 parts of Radix Isatidis, 15 parts of Folium Isatidiss, 10 parts in Poria, 30 parts of Semen Coicis core, 30 parts of Rhizoma Dioscoreaes, 10 parts of the Rhizoma Atractylodis Macrocephalaes, 10 parts of Radix Pseudostellariaes, 10 parts of Radix Et Rhizoma Rhei, 10 parts of Radix Scutellariaes, 6 parts of Cortex Phellodendris, 10 parts in Radix Glycyrrhizae, 6 parts of the Radixs Angelicae Dahuricae, 6 parts of Radix Platycodoniss, 12 parts in the Radix Rehmanniae, 10 parts of Periostracum Cicadaes.
3. according to show effect the repeatedly medicine of genital herpes of claim 1 or 2 said treatments, it is characterized in that: said agents is granule, tablet, capsule or pill.
4. according to show effect the repeatedly medicine of genital herpes of claim 1 or 2 said treatments, it is characterized in that: also comprise acyclovir slice in the said medicine.
5. claim 1 or the 2 treatments method for preparing of medicine of genital herpes of showing effect repeatedly, its step is following:
1) takes by weighing raw material according to proportioning, and medicine is removed impurity, clean;
2) said medicine is placed heating kettle, adding simultaneously is the water of 8 times of amounts of drug weight, invades bubble 2 and is as a child boiling 3 hours the back, filters, and collects filtrating;
3) add water logging once more and do not have medicinal residues, boiled one hour, filter, collect filtrating;
4) twice filtrating is merged the extractum that becomes 1:1 with concentrating under reduced pressure, oven dry is ground into fine powder, adds an amount of dextrin, abundant mix homogeneously, and with No. 0 capsule, every 0.5 restrains to pack into and gets final product.
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| CN 201110446259 CN102488851B (en) | 2011-12-28 | 2011-12-28 | Drug for treating recurrent genital herpes and preparation method thereof |
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| CN 201110446259 CN102488851B (en) | 2011-12-28 | 2011-12-28 | Drug for treating recurrent genital herpes and preparation method thereof |
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| CN104042800A (en) * | 2014-06-30 | 2014-09-17 | 邹金林 | Compound traditional Chinese medicine preparation for treating herpes simplex and preparation method thereof |
| CN104189649A (en) * | 2014-09-19 | 2014-12-10 | 广西中医药大学 | Traditional Chinese medicine composition for treating recurrent genital herpes |
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| 汤志仁等: "增损双解散加减治疗生殖器疱疹", 《江苏中医药》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104042800A (en) * | 2014-06-30 | 2014-09-17 | 邹金林 | Compound traditional Chinese medicine preparation for treating herpes simplex and preparation method thereof |
| CN104189649A (en) * | 2014-09-19 | 2014-12-10 | 广西中医药大学 | Traditional Chinese medicine composition for treating recurrent genital herpes |
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