CN101278982A - Chinese medicine compound preparation for curing acute or chronic hepatitis B and method of preparing the same - Google Patents
Chinese medicine compound preparation for curing acute or chronic hepatitis B and method of preparing the same Download PDFInfo
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- CN101278982A CN101278982A CNA2007101062804A CN200710106280A CN101278982A CN 101278982 A CN101278982 A CN 101278982A CN A2007101062804 A CNA2007101062804 A CN A2007101062804A CN 200710106280 A CN200710106280 A CN 200710106280A CN 101278982 A CN101278982 A CN 101278982A
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- chinese medicine
- chronic hepatitis
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- 239000003814 drug Substances 0.000 title claims abstract description 23
- 150000001875 compounds Chemical class 0.000 title claims abstract description 17
- 208000002672 hepatitis B Diseases 0.000 title claims abstract description 12
- 206010059193 Acute hepatitis B Diseases 0.000 title claims abstract description 10
- 208000000419 Chronic Hepatitis B Diseases 0.000 title claims abstract description 10
- 230000001154 acute effect Effects 0.000 title claims abstract description 10
- 208000037628 acute hepatitis B virus infection Diseases 0.000 title claims abstract description 10
- 238000002360 preparation method Methods 0.000 title abstract description 12
- 238000000034 method Methods 0.000 title abstract 3
- 244000208060 Lawsonia inermis Species 0.000 claims abstract description 11
- 230000000694 effects Effects 0.000 claims abstract description 7
- 229940079593 drug Drugs 0.000 claims abstract description 5
- 210000004185 liver Anatomy 0.000 claims abstract description 4
- 206010019668 Hepatic fibrosis Diseases 0.000 claims abstract description 3
- 230000006870 function Effects 0.000 claims abstract description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 25
- 239000000706 filtrate Substances 0.000 claims description 10
- 241000283690 Bos taurus Species 0.000 claims description 9
- 241000628997 Flos Species 0.000 claims description 9
- 239000002023 wood Substances 0.000 claims description 9
- 239000009636 Huang Qi Substances 0.000 claims description 8
- 239000012141 concentrate Substances 0.000 claims description 5
- 230000006837 decompression Effects 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 5
- 238000001914 filtration Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 5
- 238000001556 precipitation Methods 0.000 claims description 5
- 238000004064 recycling Methods 0.000 claims description 5
- 241000700605 Viruses Species 0.000 claims description 3
- 239000008187 granular material Substances 0.000 claims description 3
- 239000002994 raw material Substances 0.000 claims description 3
- 241001529553 Scoparia <angiosperm> Species 0.000 claims description 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims description 2
- 239000002552 dosage form Substances 0.000 claims description 2
- 230000002708 enhancing effect Effects 0.000 claims description 2
- 230000036039 immunity Effects 0.000 claims description 2
- 230000003908 liver function Effects 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 231100000957 no side effect Toxicity 0.000 claims description 2
- 239000000284 extract Substances 0.000 claims 3
- 125000003158 alcohol group Chemical group 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 241001061264 Astragalus Species 0.000 abstract 1
- 241000202726 Bupleurum Species 0.000 abstract 1
- 241001516694 Cratoxylum Species 0.000 abstract 1
- 240000003279 Cratoxylum cochinchinense Species 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 241000205407 Polygonum Species 0.000 abstract 1
- 240000006079 Schisandra chinensis Species 0.000 abstract 1
- 235000008422 Schisandra chinensis Nutrition 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 231100000956 nontoxicity Toxicity 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
- 210000004233 talus Anatomy 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 206010023126 Jaundice Diseases 0.000 description 2
- 230000008506 pathogenesis Effects 0.000 description 2
- 241000208340 Araliaceae Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 102000014150 Interferons Human genes 0.000 description 1
- 108010050904 Interferons Proteins 0.000 description 1
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 1
- 235000003140 Panax quinquefolius Nutrition 0.000 description 1
- 241000545442 Radix Species 0.000 description 1
- 208000007271 Substance Withdrawal Syndrome Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 235000008434 ginseng Nutrition 0.000 description 1
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- 208000015181 infectious disease Diseases 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
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- 230000007774 longterm Effects 0.000 description 1
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- 238000002636 symptomatic treatment Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
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Abstract
The invention relates to a compound Chinese medicine preparation used for treating acute and chronic Hepatitis B and a method for preparing the compound Chinese medicine. The compound Chinese preparation is made of seven raw medicines, including henna (also called: mignonette-tree), cratoxylon ligustrinum (also called: Cratoxylum cochinchinense), astragalus, polygonum cuspidate, herba artemisiae scopariae, schisandra and bupleurum. After undergoing certain processes, the seven raw medicines and proper excipient are mixed and processed and the compound Chinese medicine is obtained by split charging according to different preparation requirements. The invention is designed to offer the patients with acute and chronic Hepatitis B with the special compound Chinese medicine preparation. The special compound Chinese medicine preparation has the functions of immune improvement, hepatic fibrosis resistance, anti-inflammation and liver protection. In addition, the special compound Chinese medicine preparation has the advantages of short treating period, good curative effect and no toxicity and side effect. And after recovery, the acute and chronic Hepatitis B does not return easily.
Description
Technical field
The present invention relates to a kind of Chinese traditional compound medicine for the treatment of acute or chronic hepatitis B and preparation method thereof.
Background technology
China is hepatitis B state occurred frequently, these disease grievous injury its people's health, it is the very high a kind of infectious disease of sickness rate, long with the course of disease, repeatedly difficult more, some patient can develop into liver cirrhosis, it is its characteristics that minority can develop into hepatocarcinoma, makes us hearing Hepatic and becomes, and doctor trained in Western medicine is mainly controlled with " lamivudine-heptodin ", interferon and symptomatic treatment at present, its defective is that curative effect is slow, the course of treatment is long, expense is high, drug withdrawal easily repeatedly, patient is difficult to adhere to; Tcm prescription is controlled medication by dialectical opinion, but plus-minus is many, must fry in shallow oil into decoction, and is consuming time, takes extremely inconvenient.
Summary of the invention
The scheme of the main technical problem to be solved in the present invention is, according to understanding and the treatment criterion of motherland's traditional medicine to the hepatitis B etiology and pathogenesis, ginseng is studied carefully up-to-date pharmacological research achievement at present, recognize that the main cause that this disease is difficult to fully recover is that patient's autoimmunity is low, be difficult to opposing and remove virus, cause each internal organs founction metabolism imbalance in the body, then it is difficult to aggravate disease, the present invention presses treatment must aim at the pathogenesis of disease, the strengthening vital QI to eliminate pathogenic factors principle, selected heat-clearing and toxic substances removing, supplementing QI for promoting the production of body fluid, removing dampness and eliminating jaundice, hard masses softening and resolving, depressed liver-energy dispersing and QI regulating class Chinese medicine scientific composition, it is had suppresses and removing virus, the enhancing human body immunity function, antiinflammatory protects the liver, anti-hepatic fibrosis, improve the effect of liver function, thereby reach good therapeutic effect.
The present invention is the Chinese traditional compound medicine of being made by following weight proportioning raw material: Flos Impatientis (another name: 8-45 part mignonettetree), cattle wood (another name: 8-45 part Folium cratoxyli ligustrini), Radix Astragali 6-45 part, Rhizoma Polygoni Cuspidati 6-35 part, Herba Artemisiae Scopariae 10-45 part, Fructus Schisandrae Chinensis 6-45 part, Radix Bupleuri 8-35 part.
The technical problem to be solved in the present invention can also further be optimized by following technical scheme, and optimum weight proportioning of the present invention is:
Flos Impatientis (another name: mignonettetree) 10 parts, cattle wood (another name: Folium cratoxyli ligustrini) 10 parts, 8 parts of the Radixs Astragali, 8 parts of Rhizoma Polygoni Cuspidati, 15 parts of Herba Artemisiae Scopariaes, 8 parts of Fructus Schisandrae Chinensis, 10 parts of Radix Bupleuri.
The technical problem to be solved in the present invention can also further be reached by following technical scheme, and the said preparation of the present invention is a said dosage form on any pharmaceutics.
The present invention is very good to jaundice, pain, appetite decline, liver shape anomaly, disease curative effect such as weak, presses the such scheme medication, and through long-term clinical practice among the people, it is evident in efficacy to treat acute and chronic hepatitis B.Characteristics: have no side effect, short treating period, produce effects is fast, cure rate is high, be difficult for repeatedly, inexpensive, taking convenience.
Mignonettetree), cattle wood (another name: Folium cratoxyli ligustrini), the Radix Astragali, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Fructus Schisandrae Chinensis, Radix Bupleuri soak the back in the prescription ratio and decoct two to four times the preparation method of Chinese traditional compound medicine of the present invention is as follows: with Flos Impatientis (another name:, preferably decoct three times, collecting decoction, filter, add ethanol after filtrate decompression concentrates and reach 60%～70% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize, add appropriate amount of auxiliary materials again, mixing is made various preparations.
The specific embodiment:
Embodiment 1:
Get Flos Impatientis (another name: 20g mignonettetree), cattle wood (another name: 20g Folium cratoxyli ligustrini), Radix Astragali 15g, Rhizoma Polygoni Cuspidati 16g, Herba Artemisiae Scopariae 25g, Fructus Schisandrae Chinensis 15g, Radix Bupleuri 20g soaks the back and decocts three times, and collecting decoction filters, add ethanol after filtrate decompression concentrates and reach 65% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize adds appropriate amount of auxiliary materials, and tabletting is made tablet.
Embodiment 2:
Get Flos Impatientis (another name: 30g mignonettetree), cattle wood (another name: 30g Folium cratoxyli ligustrini), Radix Astragali 25g, Rhizoma Polygoni Cuspidati 25g, Herba Artemisiae Scopariae 35g, Fructus Schisandrae Chinensis 25g, Radix Bupleuri 30g soaks the back and decocts three times, and collecting decoction filters, adding ethanol after filtrate decompression concentrates and reach 68%, leave standstill after-filtration and remove precipitation to containing the alcohol amount. filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize, add appropriate amount of auxiliary materials, make granule, divide encapsulated.
Embodiment 3:
Get Flos Impatientis (another name: 100g mignonettetree), cattle wood (another name: 100g Folium cratoxyli ligustrini), Radix Astragali 80g, Rhizoma Polygoni Cuspidati 80g, Herba Artemisiae Scopariae 150g, Fructus Schisandrae Chinensis 80g, Radix Bupleuri 100g soaks the back and decocts three times, and collecting decoction filters, add ethanol after filtrate decompression concentrates and reach 68% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize adds appropriate amount of auxiliary materials, make granule, divide the bag of packing into to become electuary.
Above embodiment only is for the present invention is further illustrated, and scope of the present invention is not subjected to the limitation of illustrated embodiment.
Claims (5)
- One kind the treatment acute and chronic hepatitis B Chinese traditional compound medicine, it is characterized in that being that raw materials used proportioning consumption is a weight portion:Flos Impatientis (another name: 8-45 part cattle wood (another name: 8-45 part Folium cratoxyli ligustrini) mignonettetree)Radix Astragali 6-45 part Rhizoma Polygoni Cuspidati 6-45 part Herba Artemisiae Scopariae 10-45 part Fructus Schisandrae Chinensis 6-45 partRadix Bupleuri 8-35 part.
- 2. the Chinese traditional compound medicine of the acute and chronic hepatitis B of treatment according to claim 1, wherein the optimum weight proportioning of each raw material is:Flos Impatientis (another name: 10 parts of cattle wood (another names: Folium cratoxyli ligustrini) 10 parts mignonettetree)10 parts of 8 parts of Radix Bupleuri of 15 parts of Fructus Schisandrae Chinensis of 8 portions of Herba Artemisiae Scopariaes of 8 parts of Rhizoma Polygoni Cuspidati of the Radix Astragali.
- 3. as the production method of the arbitrary said Chinese traditional compound medicine of claim 1 to 2, it is characterized in that Flos Impatientis (another name: mignonettetree), cattle wood (another name: Folium cratoxyli ligustrini), the Radix Astragali, Rhizoma Polygoni Cuspidati, Herba Artemisiae Scopariae, Fructus Schisandrae Chinensis, Radix Bupleuri is soaked the back and is decocted two to four times, preferably decoct three times, collecting decoction, filter, add ethanol after filtrate decompression concentrates and reach 60%～70% to containing the alcohol amount, leave standstill after-filtration and remove precipitation, filtrate recycling ethanol also is condensed into thick paste, cold drying, pulverize adds appropriate amount of auxiliary materials, makes the various dosage forms such as the capsule that can form on the pharmaceutics, tablet, granule, oral agents such as oral solutions.
- 4. according to claim 1,2,3 described a kind of Chinese traditional compound medicines for the treatment of acute or chronic hepatitis B, it is characterized in that: have suppress and remove that virus, enhancing human body immunity function, antiinflammatory protect the liver, anti-hepatic fibrosis, improve liver function, short treating period, produce effects is fast, cure rate is high, difficult repeatedly, have no side effect, inexpensive, taking convenience.
- 5. as the said Chinese traditional compound medicine of claim 1 to 2, it is characterized in that said extract is alcohol extract and/or water extract.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101062804A CN101278982A (en) | 2007-05-24 | 2007-05-24 | Chinese medicine compound preparation for curing acute or chronic hepatitis B and method of preparing the same |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101062804A CN101278982A (en) | 2007-05-24 | 2007-05-24 | Chinese medicine compound preparation for curing acute or chronic hepatitis B and method of preparing the same |
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| Publication Number | Publication Date |
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| CN101278982A true CN101278982A (en) | 2008-10-08 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNA2007101062804A Pending CN101278982A (en) | 2007-05-24 | 2007-05-24 | Chinese medicine compound preparation for curing acute or chronic hepatitis B and method of preparing the same |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101889998A (en) * | 2010-05-28 | 2010-11-24 | 暨南大学 | A composition and its application in the preparation of TR3 receptor inducer |
| CN104857112A (en) * | 2015-05-13 | 2015-08-26 | 柳州市耕青科技有限公司 | Liver-soothing nutrient soup |
| CN105832784A (en) * | 2016-06-17 | 2016-08-10 | 中国热带农业科学院热带作物品种资源研究所 | Mignonettetree extract, extraction method thereof and application |
-
2007
- 2007-05-24 CN CNA2007101062804A patent/CN101278982A/en active Pending
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101889998A (en) * | 2010-05-28 | 2010-11-24 | 暨南大学 | A composition and its application in the preparation of TR3 receptor inducer |
| CN101889998B (en) * | 2010-05-28 | 2012-10-03 | 暨南大学 | Composition and application thereof as TR3 receptor inducer |
| CN104857112A (en) * | 2015-05-13 | 2015-08-26 | 柳州市耕青科技有限公司 | Liver-soothing nutrient soup |
| CN105832784A (en) * | 2016-06-17 | 2016-08-10 | 中国热带农业科学院热带作物品种资源研究所 | Mignonettetree extract, extraction method thereof and application |
| CN105832784B (en) * | 2016-06-17 | 2020-08-11 | 中国热带农业科学院热带作物品种资源研究所 | A kind of Hamparia flower extract and its extraction method and application |
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| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
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Open date: 20081008 |