CN102114133B - Ointment with function of treating diabetes and preparation method thereof - Google Patents
Ointment with function of treating diabetes and preparation method thereof Download PDFInfo
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Abstract
The invention relates to ointment with a function of treating diabetes and a preparation method thereof. The ointment disclosed by the invention is prepared by the method with the following steps of: weighing finger citron, citron, pumpkin, purslane, wolfberry fruit, lotus leaf, tuckahoe and kudzu root in parts by weight; mixing the raw materials; adding water for decocting twice, wherein adding 10 times of water in weight and decocting for 2 hours for the first time, and adding 8 times of water in weight and decocting for 1.5 hours for the second time; filtering the extracted solutions decocted twice respectively by a sieve of 160-180 meshes, concentrating the filtrate until the density is 1.23-1.26g/cm<3> to obtain extract; and mixing the extract with maltitol in parts by weight of 1:(2-4) to obtain the ointment. The ointment with the function of treating diabetes can nourish islet cells, improve the islet function, effectively control the glycogenetic index of food, reduce the fasting blood glucose and postprandial blood glucose, reduce the dosage of medicament for treating diabetes and improve the quality of life.
Description
Technical field
The present invention relates to a kind of unguentum and preparation method thereof, particularly relate to a kind of unguentum with treatment diabetes function and preparation method thereof.
Background technology
Diabetes are a kind of whole body chronic metabolic disease that determined by gene.Its main feature is hyperglycemia.According to the suggestion of the World Health Organization (WHO) and expert group of IDF (IDF), diabetes can be divided into 4 kinds of I type, II type, other specific types and gestational diabetes.
The way of existing treatment diabetes: insulin injection and take antidiabetic drug for insulin disappearance and high these format surfaces of blood glucose, and the most basic pancreatic function and cell viability are taken measures.Correct direction is to recover the normal function of pancreas and cell, recovers the instinct of human body and natural capacity of self-regulation.
Traditional diabetic diet control therapy, generally adopt and do not eat sugary food, sugarfree foods on market adopts the method for not sugaring or adds the sweeting agents such as not sugary xylitol, increases merely the mouthfeel of sweet taste, causes diabetics saccharide source disappearance.
As everyone knows, sugar is one of indispensable important nutrient of human body, carry out mechanical control blood glucose with the absorption of not absorbing sugar or few picked-up sugar or rely on medicine to reduce sugar and reach so-called criterion of acceptability, just think and well controlled diabetes, this is very large mistaken ideas.Many dieletic foodstuffs on market, the overwhelming majority develops under this theory, even some is mixed the genuine with the fictitious, more seriously, the unscientific publicity of many sugarfree foods producer, causes unnecessary the seeing of patient " sugar " fear, cause the reduction of patient's index number of price, body constitution to decline, resistance reduces, and diabetes continue development, and cause serious complication.Bring larger misery to patient, for treatment from now on has also brought very large difficulty.
Summary of the invention
The object of this invention is to provide one can nourishing pancreas islet cell, improve islet function, effectively control the sugared index of life of food, reduce on an empty stomach and post-prandial glycemia, reduce the consumption for the treatment of diabetes medicament, the unguentum with treatment diabetes function of improving the quality of living.
Another object of the present invention is to provide a kind of preparation method of the unguentum with treatment diabetes function.
The present invention adopts following technical scheme:
A kind of unguentum with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 15～20 parts of Fructus Citri Sarcodactylis, 13～16 parts of Fructus Citris, 15～20 parts, Fructus Cucurbitae moschatae, 10～14 parts of Herba Portulacaes, 10～14 parts of Fructus Lycii, 13～16 parts, Folium Nelumbinis, 15～18 parts of 10～13 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
A kind of preparation method of the unguentum with treatment diabetes function, it is characterized in that it is made up of following steps: the first step: take by weight: 15～20 parts of Fructus Citri Sarcodactylis, 13～16 parts of Fructus Citris, 15～20 parts, Fructus Cucurbitae moschatae, 10～14 parts of Herba Portulacaes, 10～14 parts of Fructus Lycii, 13～16 parts, Folium Nelumbinis, 15～18 parts of 10～13 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
The invention has the beneficial effects as follows: patient can add unguentum of the present invention the ratio of 8～14g according to every 100g food, add in flour, rice flour and make various food uses, also can directly add in the food such as medicated porridge, milk, beverage edible.
Unguentum treatment diabetes of the present invention have following features:
1, safety: product of the present invention is selected not only edible but also natural plants that can be medicinal, has no side effect, environmental protection.
2, convenient: use product of the present invention, patient is easy to use, and therapeutic effect is good.
3, evident in efficacy: to use product of the present invention, can make general patient's glycemic control steady, the symptom of alleviation physical fatigue etc.
In paste medicine formula of the present invention, the effect of each crude drug is:
Fructus Citri Sarcodactylis: pungent, hardship, sweet, temperature, nontoxic, enter liver, spleen, stomach three warps, there are the multiple medicinal functions such as activating QI to eliminate phlegm, cough-relieving relieving distension, the liver soothing and the spleen invigorating stomach function regulating." book on Chinese herbal medicine is new again " calls it can control gas soothing liver-QI.In side taking as monarch drug, depressed liver-energy dispersing and QI regulating, complies with liver bar soothing the liver.Normally whole body QI movement being in harmonious way of the catharsis function of liver, QI and blood and tune, meridians tonneau, the functional activity of internal organs organ maintains normally, and the defeated cloth metabolism side of the operation of blood, body fluid and cereal nutrient is able to normally.If liver imbalance is smooth, whether mechanism of qi disorder this liter or not, and the cereal nutrients such as blood glucose can not be stagnant in blood with the gas of the clear sun defeated cloth whole body, occurs hyperglycemia.Or do not fall and fall, let out under precise and tiny, there is glucose in urine.Further cause the defeated cloth disorder of other cereal nutrient such as fat, protein, cause many complication.
Fructus Lycii: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear.Modern pharmacological research proves that wolfberry fruit extract can significantly and lastingly reduce rat blood sugar, increases carbohydrate tolerance.
Fructus Cucurbitae moschatae: carry according to " the southern regions of the Yunnan Province book on Chinese herbal medicine ": Fructus Cucurbitae moschatae is warm in nature, and sweet in the mouth is nontoxic, enters spleen, stomach two warps, energy moistening lung qi-benefitting, the row of reducing phlegm is dense, and anthelmintic removing toxic substances, controls and coughs Zhichuan, treats lung abscess and constipation, and has the effect such as diuresis, beauty treatment.Squash polyoses is a kind of nonspecific immunity strengthening agent, can improve the immunologic function of body, promotes cytokine to generate, and by approach such as complement activations, immune system is brought into play to many-sided regulatory function.
Herba Portulacae: heat-clearing and toxic substances removing, eliminating pathogenic heat from blood to cure dysentery, dehumidifies treating stranguria.Have removing toxic substances and promoting subsidence of swelling, antiinflammatory, quenches the thirst, diuresis.Modern pharmacology research shows, Herba Portulacae contains abundant fatty acid and vitamin A sample material.
Folium Nelumbinis: delicate fragrance rises loose; There is summer heat relieving and dampness eliminating, spleen invigorating yang invigorating, effect of dissipating blood stasis hemostasis.Modern pharmacology research shows, Folium Nelumbinis has effect for reducing blood fat.
Poria: the flat slightly sweet flavor of property, enter the heart, lung, spleen channel, there is invigorating spleen to remove dampness, invigorating the spleen and regulating the stomach, effect of mind tranquilizing and the heart calming.Modern pharmacology research shows, Poria has certain effect at diuresis, calmness, anti-tumor aspect.
Radix Puerariae: induce sweat and bring down a fever, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, thirsty, quench one's thirst.Modern pharmacology research shows, Radix Puerariae has the effect of blood sugar lowering, spasmolytic, increase brain and crown vascular flow amount.
Fructus Citri: warm in nature, acrid in the mouth, hardship, acid, vexed for breast abdominal distention, distending pain over the hypochondrium, cough with copious phlegm.Modern pharmacology research shows, Fructus Citri has antiinflammatory, antivirus action.
In side, taking Fructus Citri Sarcodactylis, Fructus Citri as monarch drug, depressed liver-energy dispersing and QI regulating, complies with liver bar soothing the liver; With Fructus Lycii, Radix Puerariae is ministerial drug, and benefiting qi and nourishing yin coordinates monarch drug, performance curative effect; Taking Fructus Cucurbitae moschatae, Herba Portulacae, Folium Nelumbinis, Poria as adjuvant, regulate all medicine property of medicine.
Adopt the present invention to treat diabetes clinical treatment standard as follows:
Eat unguentum of the present invention 1-2 times every day, and each 6-10 grams 8 weeks is a course for the treatment of;
Effective standard is: use 1 course for the treatment of of unguentum of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) disappears, fasting glucose≤7.0mmol/L, or blood glucose is treated front decline >=30%, glycolated hemoglobin < 6.5%.
Effectively standard is: use 1 course for the treatment of of unguentum of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) obviously changes, and fasting glucose≤8.3mmol/L or blood glucose are treated front decline >=10%, glycolated hemoglobin 6.5～7.5%.
Invalid standard is: use 1 course for the treatment of of unguentum of the present invention, fundamental symptoms's (polydipsia, polyphagia, polyuria, weak) is not improved, and blood glucose declines and do not reach above-mentioned standard, glycolated hemoglobin >=7.5%.
Patient's 266 examples that are put to the test, are diagnosed as type 2 diabetes mellitus through hospital above county level, without severe cardiac Liver and kidney complication, at 30～65 years old age, the edible food that adds unguentum of the present invention of experimental group, takes 56 days continuously, effective case 124 people of test-meal group, account for 46.6% of test-meal group sum; Effectively case 64 people, account for 24.1% of test-meal group sum; Ineffective Cases 78 people, account for 29.3% of test-meal group sum, total effective rate 70.7%.
Model case:
Lee × ×, man, 45 years old, diabetic history 2 years, is used after unguentum of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 7.0mmol/L by 11.5mmol/L, and 2 hours blood glucoses are down to 10.0mmol/L by 19.2mmol/L, and after 8 weeks, looking into glycolated hemoglobin is 6.0%.
Virgin × ×, female, 50 years old, diabetic history 3 years, is used after unguentum of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.8mmol/L by 12.6mmol/L, and 2 hours blood glucoses are down to 10.2mmol/L by 19.0mmol/L, and after 8 weeks, looking into glycolated hemoglobin is 6.2%.
× ×, female, 55 years old, diabetic history 4 years, is used after unguentum of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.9mmol/L by 13.4mmol/L, and 2 hours blood glucoses are down to 10.1mmol/L by 20.2mmol/L, and after 18 weeks, looking into glycolated hemoglobin is 6.3%.
Liu × ×, man, 51 years old, diabetic history 3 years, in JIUYUE, 2008 is used after unguentum of the present invention, and xerostomia is thirsty, fatigue, polyuria, polydipsia transference cure, apply after 4 weeks, fasting glucose is down to 6.3mmol/L by 11.4mmol/L, and 2 hours blood glucoses are down to 10.6mmol/L by 18.2mmol/L, and after 8 weeks, looking into glycolated hemoglobin is 5.9%.
Detailed description of the invention
Embodiment 1
A unguentum with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 15 parts of Fructus Citri Sarcodactylis, 6 parts of Fructus Citris, 17 parts, Fructus Cucurbitae moschatae, 10 parts of Herba Portulacaes, 14 parts of Fructus Lycii, 13 parts, Folium Nelumbinis, 18 parts of 10 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160 mesh sieves respectively, it is 1.23g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23g/cm
3, obtaining extractum, the ratio that is 1:2 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Embodiment 2
A preparation method with the unguentum for the treatment of diabetes function, is characterized in that it is made up of following steps: the first step: take by weight: 15 parts of Fructus Citri Sarcodactylis, 16 parts of Fructus Citris, 17 parts, Fructus Cucurbitae moschatae, 10 parts of Herba Portulacaes, 14 parts of Fructus Lycii, 13 parts, Folium Nelumbinis, 18 parts of 10 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160 mesh sieves respectively, it is 1.23g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23g/cm
3, obtaining extractum, the ratio that is 1:2 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Embodiment 3
A unguentum with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 18 parts of Fructus Citri Sarcodactylis, 13 parts of Fructus Citris, 15 parts, Fructus Cucurbitae moschatae, 14 parts of Herba Portulacaes, 12 parts of Fructus Lycii, 16 parts, Folium Nelumbinis, 16 parts of 13 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.24g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:3 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.24g/cm
3, obtaining extractum, the ratio that is 1:3 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Embodiment 4
A preparation method with the unguentum for the treatment of diabetes function, is characterized in that it is made up of following steps: the first step: take by weight: 18 parts of Fructus Citri Sarcodactylis, 13 parts of Fructus Citris, 15 parts, Fructus Cucurbitae moschatae, 14 parts of Herba Portulacaes, 12 parts of Fructus Lycii, 16 parts, Folium Nelumbinis, 16 parts of 13 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.24g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:3 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.25g/cm
3, obtaining extractum, the ratio that is 1:3 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Embodiment 5
A unguentum with treatment diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 20 parts of Fructus Citri Sarcodactylis, 15 parts of Fructus Citris, 20 parts, Fructus Cucurbitae moschatae, 12 parts of Herba Portulacaes, 10 parts of Fructus Lycii, 15 parts, Folium Nelumbinis, 15 parts of 12 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.26g/cm
3, obtaining extractum, the ratio that is 1:4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Embodiment 6
A preparation method with the unguentum for the treatment of diabetes function, is characterized in that it is made up of following steps: the first step: take by weight: 20 parts of Fructus Citri Sarcodactylis, 15 parts of Fructus Citris, 20 parts, Fructus Cucurbitae moschatae, 12 parts of Herba Portulacaes, 10 parts of Fructus Lycii, 15 parts, Folium Nelumbinis, 15 parts of 12 parts, Poria and Radix Puerariaes.Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 180 mesh sieves respectively, it is 1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 180 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.24g/cm
3, obtaining extractum, the ratio that is 1:3 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
Claims (2)
1. one kind has the unguentum for the treatment of diabetes function, it is characterized in that adopting following method to make: the first step: take by weight: 15～20 parts of Fructus Citri Sarcodactylis, 13～16 parts of Fructus Citris, 15～20 parts, Fructus Cucurbitae moschatae, 10～14 parts of Herba Portulacaes, 10～14 parts of Fructus Lycii, 13～16 parts, Folium Nelumbinis, 15～18 parts of 10～13 parts, Poria and Radix Puerariaes;
Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
2. one kind has the preparation method of the unguentum for the treatment of diabetes function, it is characterized in that it is made up of following steps: the first step: take by weight: 15～20 parts of Fructus Citri Sarcodactylis, 13～16 parts of Fructus Citris, 15～20 parts, Fructus Cucurbitae moschatae, 10～14 parts of Herba Portulacaes, 10～14 parts of Fructus Lycii, 13～16 parts, Folium Nelumbinis, 15～18 parts of 10～13 parts, Poria and Radix Puerariaes;
Second step: said components raw material is mixed, decoct with water twice, add for the first time the water of 10 times of weight, decoct 2 hours, add for the second time the water of 8 times of weight, decoct 1.5 hours, decoct extracting solution twice and filter with 160-180 mesh sieves respectively, it is 1.23～1.26g/cm that filtrate is concentrated into density
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum;
Or said components raw material is mixed, add 70% alcohol reflux twice, add for the first time 8 times of amounts of 70% ethanol, extract and reflux 2 hours; Add for the second time 6 times of amounts of 70% ethanol, extract and reflux 1.5 hours, extracted twice liquid filters with 160-200 mesh sieves respectively, and filtrate recycling ethanol, is concentrated into density 1.23～1.26g/cm
3, obtaining extractum, the ratio that is 1:2～4 according to ratio of weight and number above extractum and maltose alcohol mixes, and makes unguentum.
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Non-Patent Citations (2)
| Title |
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| 糖尿病的中医药治疗进展;胡天赤;《湖北中医杂志》;20011231;第23卷(第7期);53-54 * |
| 胡天赤.糖尿病的中医药治疗进展.《湖北中医杂志》.2001,第23卷(第7期),53-54. |
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