CN101254274A - Nano chinese medicinal composition for curing white hair alopecia and preparation - Google Patents
Nano chinese medicinal composition for curing white hair alopecia and preparation Download PDFInfo
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- CN101254274A CN101254274A CNA2008100107696A CN200810010769A CN101254274A CN 101254274 A CN101254274 A CN 101254274A CN A2008100107696 A CNA2008100107696 A CN A2008100107696A CN 200810010769 A CN200810010769 A CN 200810010769A CN 101254274 A CN101254274 A CN 101254274A
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Abstract
The invention relates to a nano-traditional Chinese medicine composition for the treatment of white hair and hair loss as well as a preparation method, which is prepared by mixing nano-active mineral substances and a traditional Chinese medicine composition and is characterized in that the weight ratio is that: 1 percent to 30 percent nano-active mineral substances and 70 percent to 99 percent traditional Chinese medicine composition; the nano-active mineral substances comprise tourmaline, maifanite, Gui gem and germanite, the weight ratio of all the components is that: 10 to 70 percent tourmaline, 0 to 40 percent maifanite, 5 to 60 percent Gui gem and 0 to 30 percent germanite; the weight ratio of all the component of the traditional Chinese medicine composition is that: 5 percent to 55 percent prepared tuber fleeceflower root, 2 percent to 17 percent ginseng, 2 percent to 20 percent danshen root, 3 percent to 18 percent Chinese angelica, 2 percent to 15 percent membranous milkvetch root, 3 percent to 10 percent fragrant solomonseal rhizome, 3 percent to 22 percent malaytea scurfpea fruit, 2 percent to 13 percent safflower, 3 percent to 35 percent Chinese arborvitae twig, 5 percent to 30 percent black bean, 4 percent to 26 percent barbary wolfberry fruit, 3 percent to 17 percent cassia bark and 3 percent to 22 percent Szechuan lovage rhizome. The nano-traditional Chinese medicine composition is characterized in that the medicine has the biological and the physical functions by adding the nano-active mineral substances, which can save the raw materials, fully precipitate the effective ingredients of the medicine, solve the original difficult problem that the effective ingredients of the traditional Chinese medicine can not be fully escaped, save the raw material by 30 percent and improve the efficacy by 3 to 5 times.
Description
Technical field:
The present invention relates to a kind of nanometer Chinese medicine composition, specifically a kind of nanometer Chinese medicine composition and preparation method for the treatment of hoariness and alopecia.
Background technology
Pursue beautiful nature for people, make the market demand of field of hair care increase day by day, bred the market space of 7,000,000,000 dollars of whole world treatment hoariness and alopecia products, the great market potential of Chinese market 10,000,000,000 RMB demonstrates the industry prospect of hair-care uniqueness.The medicine for the treatment of poliosis, alopecia in the market is numerous, existing oral medicine also has medicine for external use, wherein medicine for external use all is to adopt traditional simple processing method basically, because the restriction of material technology level, the active ingredient of leaching process Chinese crude drug can not disengage fully, the medical material waste is a lot, and this series products curative effect is slow simultaneously, treatment cycle long, DeGrain, and side effect is big.Cause the reason of this phenomenon to be, these products only have biochemical function, and do not have the biophysics function, as anion, far infrared etc.The material base that Chinese medicine is prevented and cured diseases comes from the biological activity position or activity chemistry is formed.But living organism is an extremely complicated process to absorption, metabolism, the drainage of medicine, and the pharmacodynamics effect that Chinese medicine produces can not give the credit to the distinctive chemical composition of this medicine uniquely, and is also relevant with the physical state of medicine.Therefore, prepare a kind of biochemistry and physical function of having concurrently, result of use is treated the demand that the hoariness and alopecia product is market significantly.Along with the development of nanosecond science and technology, this brand-new notion of nanometer has spread in the whole world rapidly and has come, and numerous new branch of science such as nanomaterial science, guiding principle rice biology, nanometer processing are arisen at the historic moment, and make the nano active material be applied to Chinese medicine compound preparation and are achieved.
Summary of the invention:
The purpose of this invention is to provide a kind of nanometer Chinese medicine composition and preparation method of saving raw material and eutherapeutic treatment hoariness and alopecia.
The object of the present invention is achieved like this: it is to be mixed and made by nano active mineral and Chinese medicine composition, it is characterized in that their weight ratio is: nano active mineral 1%-30%, Chinese medicine composition 70%-99%.The nano active mineral comprises the mixture of one or more formations in tourmaline, Maifanitum, GUIBAOSHI, the germanite, and each component is by weight: tourmaline 10-70%, Maifanitum 0-40%, GUIBAOSHI 5-60%, germanite 0-30%.Its particle diameter 200-5000 order, character can be that one or more mixing in nano-powder, granule or the sheet material constitute.Each component is by weight in the Chinese medicine composition: Radix Polygoni Multiflori Preparata 5%-55; Radix Ginseng 2%-17%; Radix Salviae Miltiorrhizae 2%-20%; Radix Angelicae Sinensis 3%-18%; Radix Astragali 2%-15%; Rhizoma Polygonati Odorati 3%-10%; Fructus Psoraleae 3%-22%; Flos Carthami 2%-13%; Cacumen Platycladi 3%-35%; Semen sojae atricolor 5%-30%; Fructus Lycii 4%-26%; Cortex Cinnamomi 3%-17%; Rhizoma Chuanxiong 3%-22%.
The preparation method of described nanometer Chinese medicine composition following (is example with the tincture):
1, with above-mentioned Chinese medicine (decoction pieces) roguing, clean, by the prescription weighing;
2, above-mentioned nanometer mineral matters is pressed the prescription weighing;
3, above-mentioned all Chinese medicines and nanometer mineral matters material mixing are even, to put in the hermetic container, adding 60%-95% ethanol is an amount of, covers dipping, stirs, and the room temperature lower seal was placed 5-50 days.
4, regularly adopt succusion to handle to drug solution during to reach the best effect of soaking;
5, just filter obtains leachate, and post precipitation filters once more, makes it to reach transparent free from admixture, gets the transparent medicinal liquid of final brownish red;
6, sense organ, physical and chemical index check are carried out in check, sample thief;
7, fill.
The raw-material Main Ingredients and Appearance of the above part, effect and purposes:
Tourmaline: claim tourmaline again, be a kind of under naturalness the permanent energy of flow of electronics produce a kind of Ore of electrostatic field, self can forever discharge negative aeroion and far infrared, under the room temperature in wavelength 2-18mm scope the far infrared emissivity be 92%, the anion burst size is 10000/cm3, when its with utilize the characteristic of its distinctive ionizing water molecule that medicinal liquid is carried out the nanometer activation processing after alcoholic solution contacts, make medicinal liquid produce magical effectiveness.
Maifanitum: Maifanitum has tangible four big characteristics: (one), biological activity: Maifanitum water is called activated water, and significant biological effect is arranged.(2), adsorptivity: Maifanitum is to the heavy metal ion Pb in the water, Hg, Cr, Cd, As, and poisonous and harmful substances such as organic matter, pathogenic bacteria have stronger adsorption.Adsorption rate to Pb, Hg, Cr, Cd, As reaches more than 96%, and colibacillary adsorption rate is reached 95%.It can adsorb and decompose impurity in the medicinal liquid to improve its quality.(3), mineralising: Maifanitum is soaked in the water, and water is with the mineralized water of the approximate mineral water of mineralising one-tenth, and mineral wherein and trace element all are that human body is necessary.(4), the water quality property adjusted: Maifanitum has the effect of two-ways regulation pH value, acidity or alkaline water is regulated be neutral, makes the water quality alcoholization, activation.
GUIBAOSHI: GUIBAOSHI is a kind of peculiar mineral products in Guilin, and biologically active can improve the effect of the physiological function and the two-ways regulation acid-base value of body; Can absorb, decompose, remove various materials forcefully, as: amine, chlorine, hydrargyrum, cadmium, cyanogen, Fructus Vins coccus and various pathogenic bacteria; Contain 18 kinds of trace element such as the necessary potassium of human body, sodium, calcium, magnesium, phosphorus macroelement and zinc, ferrum, selenium, copper, strontium, iodine, fluorine, metasilicic acid.Under usual conditions, four kinds of trace element (metasilicic acid, Sr, Zn, F) content reaches or approaching national beverage mineral water standard in the GUIBAOSHI dissolution fluid.Also be a kind of stone material with anion and far-infrared functional, the anion value can reach more than the 500ions/cm3, far above other geographic similar stone materials.The far infrared radiation rate is more than 90%, and fluctuation numerical value reaches more than 30,000 lonizing radiation 0.238.
Germanite:Germanite is used as medicine, and has cooling blood for hemostasis, stopping nausea and vomiting by lowering the adverse flow of QI, the effectiveness of the suppressing the hyperactive liver that relieves inflammation or internal heat.And have releasing far infrared and effect anion, and promote vasodilation, strengthen skin microcirculation, impel the medicine active ingredient fully to absorb.
Radix Polygoni Multiflori: contain nutritional labelings such as lecithin, have the merit of nourishing blood to expel wind, the effect of regulating nerve, endocrine function and hairy root nourishing is arranged, impel the melanic generation of hair, make hair more black.Simultaneously, Radix Polygoni Multiflori also contains chrysophanol and a large amount of starch.After the starch hydrolysis, Portugal's glucose of generation has good hair care effect, is the best raw material of Chinese medicine of preparation hair conditioner.Experiment showed, that according to modern pharmacology the contained lecithin of Radix Polygoni Multiflori is the important source material of cell membrane, can promote the metabolism and the growth promoter of cell, thereby delay the aging of cell, life prolonging.
The Radix Astragali: contain the trace element of several amino acids, betanin, folic acid, alkaloid and needed by human, have blood vessel dilating, improve nutrition, the control alopecia trichogenous effect of skin.Has stronger two-way immunomodulating effect simultaneously.
Radix Angelicae Sinensis: promoting the circulation of blood is arranged, enrich blood, the effect of pain relieving, skin moistening.Can expand blood capillary, the blood circulation promoting of scalp and skin, vitamin antagonist E lacks, and the Chinese medicine for external application that contains Radix Angelicae Sinensis extract can be anti-loss, the skin care hair, and make hair pitch-black shinny, can also prevent yellow hair and poliosis.
Fructus Lycii: contain the essential retinol1 of hair care, B2, C and microelements of calcium, phosphorus, ferrum etc., especially with vitamin A and C content height, in Chinese medicine for external application, add the extract of Fructus Lycii, can be anti-loss, make hair pitch-black shinny, simultaneously to the vitamin of needed by human and trace element deficiency and the yellow hair that causes, poliosis, lusterless complexion, xerosis cutis etc. all have significant curative effect.Because it can also promote the melanic generation of hair, and alopecia areata is had better curative effect.
Semen sojae atricolor:Semen sojae atricolor is flat, sweet in the mouth.Have the therapeutic method to keep the adverse QI flowing downwards in the accent, enriching yin and nourishing kidney, enrich blood make eye bright, effect such as inducing diuresis to remove edema, the black hair of invigorating blood circulation.
Rhizoma Polygonati Odorati:Rhizoma Polygonati Odorati is slightly cold, sweet, compositions such as mucous matter, vitamin A and alkaloid, tool nourishing YIN to relieve dryness, the effect of promoting the production of body fluid to quench thirst.
Flos Carthami:Flos Carthami is warm in nature, and acrid in the mouth is conventional Chinese medicine, removing blood stasis with potent drugs is arranged, the function of invigorating blood circulation, stimulate the menstrual flow.
Cortex Cinnamomi:Cortex Cinnamomi is hot in nature, acrid in the mouth, sweet.It is supporing yang to mend fire, let the fire back to its origin, and dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow, and powerful bactericidal action is arranged.
Rhizoma Chuanxiong: have dispel the wind, invigorate blood circulation, skin moistening, antipruritic effect, help the scalp nutrition improvement.Modern pharmacology proves, Rhizoma Chuanxiong energy enlarged head blood capillary, and blood circulation promoting increases hair nutrition, and makes hair that good pliability and the function that is difficult for becoming fragile be arranged, and can delay the poliosis growth, keeps hair to lubricate gloss.
Radix Salviae Miltiorrhizae: the main effect of Radix Salviae Miltiorrhizae is a blood circulation promoting and blood stasis dispelling.Owing to contain abundant vitamin and trace element zinc, copper, ferrum etc., can promote the melanic generation of hair, also can improve because of diseases such as poliosis that trace element deficiency causes, yellow hair, hair dryings.With the other medicines fit applications, multiple functions such as antipruritic, anti-dandruff, control alopecia, black hair, hair care, enhancing skin elasticity are arranged then.
Cacumen Platycladi: cold in nature, bitter and puckery flavor.Main effect is cooling blood for hemostasis, and growing and blacking hair is used for the heat in blood alopecia, early whitening of beard and hair.
Fructus Psoraleae: have nourishing the liver and kidney, strengthening muscles and invigorating stomach can be controlled the chronic diarrhea of suffering from a deficiency of the kidney, and also can be used for alopecia areata.
Technique effect of the present invention is on the basis of traditional secret recipe, and selected tens kinds of Chinese herbal medicine carry out the science compatibility, and have added the nano active mineral innovatively, forms the novel nano Chinese medicine preparation that unique nano active mineral and Chinese medicine combine.Chinese medicine among the present invention itself promptly has the good result of treatment poliosis, alopecia, with the nano active mineral with have more following innovation effect after Chinese medicine combines:
First, add the nano active mineral, after the herb liquid process nanometer activation processing, the activity of medicine and bioavailability have obtained increasing substantially, and can on the basis that keeps the former explosive component of Chinese medicine the medicine active ingredient fully be separated out, solved the difficult problem that effective components of Chinese medicinal is all overflowed, conservation 30% improves curative effect 3-5 doubly, thereby saves limited natural resources of Chinese medicinal materials in a large number;
Second, the nano active mineral that adds with utilize the characteristic of its distinctive ionizing water molecule to make medicinal liquid formation anion water after middle drug solns contacts, dwindle water clusters, surface tension descends, the medicine active ingredient focus of going directly, strengthened vegetative nerve regulating, cell activation and the metabolism ability of medicine, thereby made medicine have stronger activating blood circulation to dissipate blood stasis, dredge the meridian passage, liver and kidney tonifying effect human body.It is faster that treatment poliosis, alopecia are taken effect, and relapse rate is low.
The 3rd, the nano active mineral that adds discharges anion and far infrared, has sterilizing function, and contains the various trace elements useful to health, act on skin of head and have the microcirculatory exceptional function of the head of promotion simultaneously, clean and nutrition skin of head.
The 4th, the interpolation of nano active mineral has changed pharmacokinetic property, increases medicine to biomembranous permeability, thereby improves the therapeutic effect of Chinese medicine Transdermal absorption greatly.
At last, the interpolation of nano active mineral makes liquid PH value be alkalescence, increases dissolved oxygen concentration in the medicinal liquid, relaxes alcoholic acid penetrating odor in the medicinal liquid, makes easier acceptance on patient's sense organ.
Nano active mineral described in the present invention reserves at home is abundant, and purchase cost is low relatively.
Change list before and after the herb liquid nanometer activation processing
| Before the activation processing | After the activation processing | Authentication method |
| The medicinal liquid color | More transparent clarification | Vision is assert |
| The medicinal liquid abnormal smells from the patient | Relaxed the ethanol pungent taste, taste of Chinese medicine is soft dense | Olfactory sensation is assert |
| Alcoholic strength | Do not become | Alkograph |
| The acidity degree | Neutralization reduces | Acidity of Aikalinity test (PH reagent paper, PH test solution) |
| The medicinal liquid molecular structure | The medicinal liquid micel status architecture that diminishes is more regular | Experience the professional Molecular Detection instrument of impression |
| The mineral content trace element | Increase, abundanter | TDS electric conductance instrument test |
| Medicinal liquid single use amount | The single use amount reduces | Experience impression |
| The medicinal liquid effectiveness | Better efficacy, treatment cycle is shorter, and the patient treatment satisfaction increases | Experience impression |
| Medicinal liquid is to skin irritation | Non-stimulated, there is not irritated reaction | Experience impression |
Below in conjunction with embodiment the present invention is done with explanation.
The specific embodiment:
Embodiment one:
Weight ratio between nano active mineral raw material and raw material of Chinese medicine: nano active mineral raw material 15%, raw material of Chinese medicine 85%.Wherein nano active mineral each component and weight ratio: tourmaline 40%, GUIBAOSHI 30%, Maifanitum 25%, germanite 5%; Chinese medicine each component and weight ratio: Radix Polygoni Multiflori Preparata 35.5%, Radix Ginseng 2.3%, Radix Salviae Miltiorrhizae 2.5%, Radix Angelicae Sinensis 3.7%, the Radix Astragali 5%, Rhizoma Polygonati Odorati 3.5%, Fructus Psoraleae 5.5%, Flos Carthami 9.6%, Cacumen Platycladi (12.5%), Semen sojae atricolor 5.6%, Fructus Lycii 5.8%, Cortex Cinnamomi 4%, Rhizoma Chuanxiong 4.5%.
Preparation method (tincture):
1) with above-mentioned Chinese medicine (decoction pieces) roguing, clean, by the prescription weighing;
2) above-mentioned nanometer mineral matters is pressed the prescription weighing;
3) above-mentioned all Chinese medicines and nanometer mineral matters material mixing are even, to put in the hermetic container, adding 60%-95% ethanol is an amount of, covers dipping, stirs, and the room temperature lower seal was placed 5-50 days.
4) regularly adopt succusion to handle to drug solution during to reach the best effect of soaking;
5) just filter obtains leachate, and post precipitation filters once more, makes it to reach transparent free from admixture, gets the transparent medicinal liquid of final brownish red;
6) sense organ, physical and chemical index check are carried out in check, sample thief;
7) fill.
Embodiment two:
Weight ratio between nano active mineral raw material and raw material of Chinese medicine: nano active mineral raw material 10%, raw material of Chinese medicine 90%.Wherein nano active mineral each component and weight ratio: tourmaline 60%, Maifanitum 20%, GUIBAOSHI 20%; Chinese medicine each component and weight ratio: Radix Polygoni Multiflori Preparata 40%, Radix Ginseng 2.1%, Radix Salviae Miltiorrhizae 2.2%, Radix Angelicae Sinensis 4.1%, the Radix Astragali 5.6%, Rhizoma Polygonati Odorati 3%, Fructus Psoraleae 4.5%, Flos Carthami 3%, Cacumen Platycladi (18.2%), Semen sojae atricolor 7%, Fructus Lycii 4.3%, Cortex Cinnamomi 3%, Rhizoma Chuanxiong 3%.
Preparation method is with embodiment one.
Embodiment three:
Weight ratio between nano active mineral raw material and raw material of Chinese medicine: nano active mineral raw material 5%, raw material of Chinese medicine: 95%.Wherein nano active mineral each component and weight ratio: tourmaline 65%, GUIBAOSHI 35%; Chinese medicine each component and weight ratio: Radix Polygoni Multiflori Preparata 31.5%, Radix Ginseng 3.6%, Radix Salviae Miltiorrhizae 4.8%, Radix Angelicae Sinensis 5.2%, the Radix Astragali 7%, Rhizoma Polygonati Odorati 4%, Fructus Psoraleae 8.5%, Flos Carthami 6%, Cacumen Platycladi 10.5%, Semen sojae atricolor 6.5%, Fructus Lycii 4.1%, Cortex Cinnamomi 3.2%, Rhizoma Chuanxiong 5.1%.
Preparation method is with embodiment one.
Nanometer Chinese medicine composition described in the present invention can be processed into external goods such as tincture, lotion, spray, can use separately, also can be used as main effective component and is used for making treatment hoariness and alopecia medicine and hair care, hair growth promoting, hair washing, hair care articles.
Clinical example:
Mr. Sun, 51 years old, the civil servant, the readme sleep is very poor always, existing 7,8 years of long poliosis, almost half hair is a poliosis, hair dyeing is serious irritated, is sorely distressed.Use product of the present invention, root of hair begins to change black after 1 month, continuously treatment after 6 months the blackening hair rate reach 70%, (one month is a course of treatment after 2 months to continue to strengthen treatment, have 8 courses of treatment altogether), the poliosis forward rate reaches more than 95%, and Mr. Sun is very satisfied to treatment, do not had white hair, whole people seems that also youth how.
Mr. Liu, 34 years old, the boss of individual enterprise, readme since operating pressure big, just begin long white hair several years ago, almost accounted for now fast half, go examination in hospital also not have defect, very healthy, have only and often go to have had hair dyed.Use product of the present invention, just saw positive effect in 1 month, giving meticulous treatment of process continuous 6 courses of treatment (6 months) recovered hair color all over the face finally, and poliosis is worried thoroughly to be solved.
Miss Guan, 23 years old, the senior, slight poliosis, beginning about 15 years old, treat 3 courses of treatment after, basically do not had poliosis on the head now, see that with instrument the fine, soft fur that grows also is a black, it all is that Lycoperdon polymorphum Vitt or head are blackheads that the poliosis that finds is sometimes pulled up, and Miss Guan feels quite pleased this treatment.
Mr. Zhang, 29 years old, the readme hair did not know how just to have fallen one, has found 2 wheat harvesting periods.Mr. Zhang's this situation belongs to single oval alopecia areata, and about diameter 2cm size if untimely treatment increases the weight of possibly, is treated 1 course of treatment through using product of the present invention, and the director that comes off goes out newborn hair color, through transference cure after 4 courses of treatment, cures.
Mrs Feng, 32 years old, closely half a year, alopecia was serious, and more very, top of the head hair is especially sparse when washing and dressing, and belongs to alopecia generalisata.Use product of the present invention treatment 15 days, i.e. alopecia stops, treat 5 courses of treatment after hair recover normally.
Mr. Yang, 42 years old, belong to male's seborrheic alopecia, use product of the present invention to treat 2 courses of treatment, alopecia significantly reduces, and the top of the head has New Development to grow, and continues to treat 6 courses of treatment, reaches the patient satisfaction effect, clinical cure.
Claims (4)
1, a kind of nanometer Chinese medicine composition and preparation method for the treatment of hoariness and alopecia, it is to be mixed and made by nano active mineral and Chinese medicine composition, it is characterized in that their weight ratio is: nano active mineral 1%-30%, Chinese medicine composition 70%-99%; The nano active mineral comprises tourmaline, Maifanitum, GUIBAOSHI, germanite, and each component is by weight: tourmaline 10-70%, Maifanitum 0-40%, GUIBAOSHI 5-60%, germanite 0-30%; Each component is by weight in the Chinese medicine composition: Radix Polygoni Multiflori Preparata 5%-55; Radix Ginseng 2%-17%; Radix Salviae Miltiorrhizae 2%-20%; Radix Angelicae Sinensis 3%-18%; Radix Astragali 2%-15%; Rhizoma Polygonati Odorati 3%-10%; Fructus Psoraleae 3%-22%; Flos Carthami 2%-13%; Cacumen Platycladi 3%-35%; Semen sojae atricolor 5%-30%; Fructus Lycii 4%-26%; Cortex Cinnamomi 3%-17%; Rhizoma Chuanxiong 3%-22%.
2, the nanometer Chinese medicine composition and the preparation method of treatment hoariness and alopecia as claimed in claim 1 is characterized in that preparation method is:
A, with above-mentioned Chinese medicine roguing, clean, by the prescription weighing;
B, with above-mentioned nanometer mineral matters by the prescription weighing;
C, above-mentioned all Chinese medicines and nanometer mineral matters material mixing are even puts in the hermetic container, adds 60%-95% ethanol, covers dipping, stirs, and the room temperature lower seal was placed 5-50 days;
D, during regularly adopt succusion to handle to drug solution to reach the best effect of soaking;
E, filter just obtain leachate, and post precipitation filters once more, makes it to reach transparent free from admixture, gets the transparent medicinal liquid of final brownish red;
Sense organ, physical and chemical index check are carried out in f, check, sample thief;
G, fill.
3, the nanometer Chinese medicine composition and the preparation method of treatment hoariness and alopecia as claimed in claim 1; it is characterized in that the nano active mineral comprises the mixture of one or more formations in tourmaline, Maifanitum, GUIBAOSHI, the germanite; its particle diameter 200-5000 order, character can be that one or more mixing in nano-powder, granule or the sheet material constitute.
4, as the nanometer Chinese medicine composition and the preparation method of claim 1 and 2 described treatment hoariness and alopecias, it is characterized in that described nanometer Chinese medicine composition can be processed into external goods such as tincture, lotion, spray, can use separately, also can be used as main effective component and be used for making treatment hoariness and alopecia medicine and hair care, hair growth promoting, hair washing, hair care articles.
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