CN100361584C - Broad-spectrum antiseptics and production thereof - Google Patents
Broad-spectrum antiseptics and production thereof Download PDFInfo
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- CN100361584C CN100361584C CNB2005100661024A CN200510066102A CN100361584C CN 100361584 C CN100361584 C CN 100361584C CN B2005100661024 A CNB2005100661024 A CN B2005100661024A CN 200510066102 A CN200510066102 A CN 200510066102A CN 100361584 C CN100361584 C CN 100361584C
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- 230000002421 anti-septic effect Effects 0.000 title abstract 5
- 229940064004 antiseptic throat preparations Drugs 0.000 title 1
- 241001465754 Metazoa Species 0.000 claims abstract description 22
- 239000002994 raw material Substances 0.000 claims abstract description 13
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims abstract description 12
- -1 bis-octadecy l hydroxypropyl quaternary ammonium salt Chemical class 0.000 claims abstract description 9
- 239000002904 solvent Substances 0.000 claims abstract description 9
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims abstract description 6
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000000645 desinfectant Substances 0.000 claims description 54
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical group OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- RZJRJXONCZWCBN-UHFFFAOYSA-N alpha-octadecene Natural products CCCCCCCCCCCCCCCCCC RZJRJXONCZWCBN-UHFFFAOYSA-N 0.000 claims description 8
- BUHXFUSLEBPCEB-UHFFFAOYSA-N icosan-1-amine Chemical compound CCCCCCCCCCCCCCCCCCCCN BUHXFUSLEBPCEB-UHFFFAOYSA-N 0.000 claims description 8
- 229940038384 octadecane Drugs 0.000 claims description 8
- 238000002360 preparation method Methods 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 230000000249 desinfective effect Effects 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 5
- 238000001228 spectrum Methods 0.000 claims description 4
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 claims description 3
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 claims description 3
- 229940079593 drug Drugs 0.000 claims description 2
- 230000000968 intestinal effect Effects 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 8
- 241000700605 Viruses Species 0.000 abstract description 7
- 210000000214 mouth Anatomy 0.000 abstract description 7
- 239000005416 organic matter Substances 0.000 abstract description 7
- 208000004232 Enteritis Diseases 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 3
- 241000125945 Protoparvovirus Species 0.000 abstract description 2
- 244000052616 bacterial pathogen Species 0.000 abstract description 2
- 230000001717 pathogenic effect Effects 0.000 abstract description 2
- 230000035515 penetration Effects 0.000 abstract description 2
- 239000012528 membrane Substances 0.000 abstract 2
- 244000052769 pathogen Species 0.000 abstract 2
- 208000000655 Distemper Diseases 0.000 abstract 1
- 208000014058 canine distemper Diseases 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 31
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 18
- 229910052740 iodine Inorganic materials 0.000 description 18
- 239000011630 iodine Substances 0.000 description 18
- 230000001954 sterilising effect Effects 0.000 description 13
- 241000894006 Bacteria Species 0.000 description 11
- 238000010790 dilution Methods 0.000 description 10
- 239000012895 dilution Substances 0.000 description 10
- 238000004659 sterilization and disinfection Methods 0.000 description 10
- 241000282472 Canis lupus familiaris Species 0.000 description 5
- 230000009471 action Effects 0.000 description 5
- 244000144987 brood Species 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 230000007797 corrosion Effects 0.000 description 5
- 238000005260 corrosion Methods 0.000 description 5
- 239000000047 product Substances 0.000 description 5
- 241000191967 Staphylococcus aureus Species 0.000 description 4
- 235000005911 diet Nutrition 0.000 description 4
- 229910052751 metal Inorganic materials 0.000 description 4
- 239000002184 metal Substances 0.000 description 4
- 238000005303 weighing Methods 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 230000037308 hair color Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 241000195493 Cryptophyta Species 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 206010047700 Vomiting Diseases 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000013459 approach Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000013872 defecation Effects 0.000 description 2
- 230000037213 diet Effects 0.000 description 2
- 230000000378 dietary effect Effects 0.000 description 2
- 239000008233 hard water Substances 0.000 description 2
- 238000007654 immersion Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 210000004681 ovum Anatomy 0.000 description 2
- 150000003242 quaternary ammonium salts Chemical class 0.000 description 2
- 238000012216 screening Methods 0.000 description 2
- 238000013112 stability test Methods 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 206010067482 No adverse event Diseases 0.000 description 1
- 239000004411 aluminium Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000012752 auxiliary agent Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 238000005202 decontamination Methods 0.000 description 1
- 230000003588 decontaminative effect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 238000004332 deodorization Methods 0.000 description 1
- 208000002672 hepatitis B Diseases 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 150000002496 iodine Chemical class 0.000 description 1
- 230000005923 long-lasting effect Effects 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- RTKIYNMVFMVABJ-UHFFFAOYSA-L thimerosal Chemical compound [Na+].CC[Hg]SC1=CC=CC=C1C([O-])=O RTKIYNMVFMVABJ-UHFFFAOYSA-L 0.000 description 1
- 229940033663 thimerosal Drugs 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The present invention discloses a new antiseptic which is composed of the following raw materials of the weight portions: 8 to 20 portions of ammonium eicosyl oxide, 0.1 to 0.8 portions of iodine, 1 to 6 portions of bis-octadecy l hydroxypropyl quaternary ammonium salt, 1 to 6 portions of solubilizer and 2 to 8 portions of phosphoric acid. The antiseptic of the present invention can be taken through mouth, and can sterilize the oral cavities of animals and effectively kill various pathogenic bacteria in the intestinal tracts of animals so as to control and prevent canine distemper, parvovirus, enteritis, etc. of animals or pets. With the advantages of rapid effect taking and strong penetration force, the antiseptic of the present invention can penetrate into organic matter to rapidly kill pathogen, and can rapidly kill non-membrane viruses, membrane viruses, pathogenic organism and invasive organism at normal temperature. The present invention is a typical broad-spectrum antiseptic.
Description
Technical field
The present invention relates to a kind of disinfectant, relate in particular to a kind of wide spectrum animal disinfectant and preparation method thereof, belong to drug world.
Background technology
The main series of products of animal disinfectant are divided into iodine class, quaternary ammonium salt and other complex class products at present, these disinfectants all in various degree exist composition single, can only kill defectives such as the specific germ of part, and have residual, unstable, in the storage life, change, and not anti-organic matter, not anti-hard water, in the presence of organic matter, easily lost efficacy volatilization, in most cases skin is corrosive, more can not takes orally.
Summary of the invention
Technical problem to be solved by this invention is to overcome the deficiencies in the prior art, provide a kind of can be through the wide spectrum animal disinfectant of animal oral administration, stable storing, safety.
Technical problem to be solved by this invention realizes by following technological approaches:
A kind of wide spectrum animal disinfectant, mainly form by the raw material of following weight portion:
2～8 parts of 8～20 parts of eicosyl amine oxides, 0.1～0.8 part of iodine, 1～6 part of two octadecane hydroxypropyl quaternary ammonium salt, 1～6 part of solubilizer and phosphoric acid.
Be preferably: 12 parts of eicosyl amine oxides, 0.5 part of iodine, 3 parts of two octadecane hydroxypropyl quaternary ammonium salts, 3 parts of solubilizer and phosphatase 24 part.
Described solubilizer is conventional solubilizer, is preferably ethylene glycol, ethanol or water.
The used raw material of the present invention all can be bought from common market and obtain, and its specification is a pharmaceutical grade.
Another technical problem to be solved by this invention provides a kind of method for preparing animal disinfectant of the present invention, may further comprise the steps:
Take by weighing each raw material by following weight portion: 2～8 parts of 8～20 parts of eicosyl amine oxides, 0.1～0.8 part of iodine, 1～6 part of two octadecane hydroxypropyl quaternary ammonium salt, 1～6 part of solubilizer and phosphoric acid; Each raw material of above weight portion is mixed, promptly get disinfectant of the present invention.
Disinfectant of the present invention can oral administration, can not only carry out oral disinfecting to animal, also can effectively kill the various pathogenic bacteria in the animal intestinal, solved at one stroke of the intrusion of pathogenic microorganismss such as various viruses, bacterium, mould, fungi, hepatitis B to animal, thus control and prevented the generation of warm, the parvovirus, enteritis etc. of animal or pet; This product has not only carried out cleaning but also can further intercept germ the oral cavity invading; Disinfectant speed of action of the present invention is fast, penetration is strong, can penetrate and kill pathogene in the organic matter rapidly, can kill " non-film virus and band film virus " at normal temperatures rapidly, and pathogenicity and invasive organism, comprise bacterium, mycoplasm hyopneumoniae, virus, worm's ovum, algae, brood cell etc., be a kind of typical broad-spectrum disinfectant, can use for a long time thereby solved the single of disinfectant.
The using method of animal disinfectant of the present invention and consumption: disinfectant of the present invention and water be can be used for animal, environment and medical apparatus sterilizing after by dilution in 1: 200; Occupation mode: select different modes for use according to the object that uses, can select sprinklings, immersion for use, take orally, approach or mode such as mouthspray; As guidance, for example, can adopt the mode of sprinkling when being used for environment disinfected; When being used for medical apparatus sterilizing, can adopt the mode of immersion; When being used for sterilizing in animal oral cavity and the body, oral administration disinfectant of the present invention.
In a word, disinfectant of the present invention has the following advantages: 1) have the advantage of iodine disinfectant and quaternary ammonium salt disinfectant concurrently, speed of action is fast, can penetrate and kill pathogene in the organic matter rapidly; Also have good cleaning decontamination and deodorization function; 2) can kill all pathogenic and invasive organism, comprise bacterium, mycoplasm hyopneumoniae, virus, worm's ovum, algae, brood cell etc., be a kind of typical broad-spectrum disinfectant; 3) influence that not polluted by organic matter is not subjected to the influence of water hardness, thereby the dilution of available hard water is used; 4) have unique teriodide, can exist in the environment highly stablely, be not subjected to light, heat, temperature, effects of humidity change, keep normal sterilizing power and long-lasting fully; 5) under extremely low concentration (＜25ppm), still keep the stability of iodine and strong bactericidal properties, stored under the room temperature 3 years, content of iodine is constant; 6) used whole composition is the auxiliary agent that is widely used in cosmetics, medicine, washing agent, does not have toxicity fully, and can dissolve each other with water; 7) recommending under the working concentration, to the people, poultry, nontoxic, non-stimulated, the no burn into of fowl animal do not have to be accumulated with residual, can use for a long time.
Further describe beneficial effect of the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never limit the scope of the invention.
Embodiment
The preparation of [embodiment 1] disinfectant of the present invention.
Take by weighing each raw material (unit: kg): eicosyl amine oxide 8, iodine 0.1, two octadecane hydroxypropyl quaternary ammonium salt 1, water 1, phosphoric acid 2 by following weight; Each raw material of above weight portion is mixed promptly in reactor.
The preparation of [embodiment 2] disinfectant of the present invention.
Take by weighing each raw material (unit: kg): eicosyl amine oxide 20, iodine 0.8, two octadecane hydroxypropyl quaternary ammonium salt 6, ethanol 6 and phosphoric acid 8 by following weight; Each raw material of above weight portion is mixed promptly in reactor.
The preparation of [embodiment 3] disinfectant of the present invention.
Take by weighing each raw material (unit: kg): eicosyl amine oxide 12, iodine 0.5, two octadecane hydroxypropyl quaternary ammonium salt 3, ethylene glycol 3 and phosphatase 24 by following weight; Each raw material of above weight portion is mixed promptly in reactor.
The disinfection effect test of [test example 1] disinfectant of the present invention
One, for test agent: the disinfectant that the embodiment of the invention is prepared.During use, disinfectant of the present invention and water were used after the dilution proportion by 1: 200.
Two, laboratory animal: rich U.S. dog, 48, be divided into 4 groups at random, 12 every group, live in 4 conditions, the identical doghouse of environment respectively, i.e. 1,2,3 and No. 4 house.
Three, test method and result.
1, test method
No. 1 house: with once for test agent per 2 days environment disinfecteds, simultaneously during defecation once a day, mouthspray was had a bath once with this product thimerosal once a day in 3 days.
No. 2 houses: with this product disinfectant 2 days environment disinfecteds once, simultaneously during defecation once a day.
No. 3 houses: environment is sterilization not, and oral disinfecting once a day.
No. 4 houses: do not carry out any measure of disinfecting.
2, result of the test:
No. 1 house: experimental dogs hair color light, dietary amount is fabulous, and free from extraneous odour, oral cavity free from extraneous odour are lively and lovely in the house, and the no state of an illness occurs in 3 months, survival rate 100%.
No. 2 houses: free from extraneous odour, experimental dogs hair color do not have light in the house, and diet is general, peculiar smell are arranged, sometimes with diarrhoea and symptoms of emesis in the house.
No. 3 houses: peculiar smell, experimental dogs oral cavity free from extraneous odour are arranged in the house.Dietary amount is good, does not have enteritis to occur, but other symptoms are arranged.
No. 4 houses: peculiar smell, experimental dogs hair color dimness are arranged in the house, do not have light, diet is general, and with diarrhoea and symptoms of emesis, other state of an illness happen occasionally sometimes.
Above-mentioned result of the test explanation, disinfectant of the present invention all has good sterilization, sterilization functions for animal oral cavity, enteron aisle and surrounding environment.
The performance measurement of [test example 2] disinfectant of the present invention
1, available iodine content is measured: measurement result: disinfectant available iodine content of the present invention is 5100mg/L.
2, neutralizer screening test:
Show in the trial test, this neutralizer can be removed the disinfective action of the concentration disinfectant that tries, neutralizer, neutralized reaction product test organisms unrestraint effect, medium is had no adverse effects, formal neutralizer test acts on 3min with 1: 1000 disinfectant disinfectant of the present invention (containing available iodine 5100mg/L), and test repeats 5 times, average, the results are shown in Table 1:
Table 1 disinfectant neutralizer of the present invention screening test result
| The test grouping | 1 | 2 | 3 | 4 | 5 |
| Total number of bacteria | 2.12×10 4 | 6.27×10 7 | 6.29×10 7 | 84 | 6.42×10 7 |
3. quantitative sterilizing test:
Bacterial classification adopts Escherichia coli, staphylococcus aureus, withered black brood cell, and test repeats five times, and the result gets its mean value.Get disinfectant 1/2000 dilution of the present invention, containing available iodine 2.55mg/L effect was 99.93% to colibacillary killing rate in 5 minutes; Disinfectant 1/1000 dilution of the present invention, containing 1 minute killing rate to staphylococcus aureus of available iodine 5.10mg/l effect is 99.98%; Disinfectant 1/20 dilution of the present invention, containing available iodine 255mg/L effect was 100% to withered black bud killing rate in 15 minutes.Result of the test sees Table 2:
The quantitative disinfection test result of table 2 disinfectant of the present invention
| Bacterial classification | Dilution factor | Available iodine content (mg/L) | Action time (min) | The average bacterium number of experimental group (cfu/ml) | The average bacterium number of control group (cfu/ml) | Sterilizing rate (%) |
| The withered black brood cell of Escherichia coli staphylococcus aureus | 1/500 1/1000 1/2000 1/500 1/1000 1/2000 1/20 1/40 | 10.20 5.10 2.55 10.20 5.10 2.55 255 127.5 | 1 3 5 1 3 5 1 3 5 1 3 5 1 3 5 1 3 5 15 30 60 15 30 60 | 12 0 0 1.76×10 4 1.22×10 4 3.04×10 3 1.64×10 4 9.76×10 4 3.72×10 4 8 0 0 2.60×10 4 1.87×10 4 1.58×10 4 3.92×10 6 3.65×10 6 3.60×10 6 0 0 0 4.83×10 6 4.61×10 6 4.48×10 6 | 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 5.67×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 5.65×10 6 5.65×10 6 5.65×10 6 5.65×10 6 5.65×10 6 5.65×10 6 | ＞99.99 100 100 99.97 99.98 99.99 99.71 99.82 99.93 ＞99.99 100 100 99.93 99.95 99.96 99.08 99.10 99.10 99.11 100 100 100 14.5132 18.4071 |
4. organic substance influence test
Bacterial classification adopts staphylococcus aureus, and test repeats five times, gets its mean value.The organic substance influence test is compared with quantitative disinfection test result.Sterilizing rate is constant substantially, shows that organic matter does not have influence to the Disinfection Effect of disinfectant of the present invention.See table 3 for details:
The organic substance influence result of the test of table 3 disinfectant of the present invention
| Serum-concentration (%) | Dilution factor | Available iodine content (mg/L) | Action time (min) | The average bacterium number of experimental group (cfu/ml) | The average bacterium number of control group (cfu/ml) | Sterilizing rate (%) |
| 0 10 brood cells | 1/500 1/1000 1/500 1/1000 | 10.20 5.10 10.20 5.10 | 1 3 5 1 3 5 1 3 5 1 3 5 | 8 0 0 2.60×10 4 1.87×10 4 1.58×10 4 1 0 0 5.24×10 3 4.40×10 3 1.58×10 4 | 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 4.08×10 7 1.60×10 7 1.60×10 7 1.60×10 7 1.60×10 7 1.60×10 7 4.08×10 7 | ＞99.99 100 100 99.93 99.95 99.96 ＞99.99 100 100 99.95 99.96 99.97 |
5. stability test:
After 14 days, the effective ingredient of disinfectant of the present invention (available iodine) content descends 17.65%, and disinfectant good stability of the present invention is described 54-57 ℃ of preservation, and result of the test sees following table 4 for details:
The stability test result of table 4 disinfectant of the present invention
| Time (my god) | Available iodine content (mg/L) | Percent of loss (%) |
| 0 14 | 5100 4200 | 0 17.65 |
6. metal protection test:
The results are shown in Table 5:
The metal protection result of the test of table 5 disinfectant of the present invention
| Metal | Disinfectant | Weight metal | ||||
| Classification | Dilution factor | Available iodine content | Before | After | Corrosion rate | Corrosion |
| The firm aluminium of stainless steel carbon | 1/20 1/20 1/20 | 255 distilled water, 255 distilled water, 255 distilled water | 6.4422 6.4077 6.2706 6.3059 2.2598 2.2928 | 6.4418 6.4077 6.2558 6.2298 2.2586 2.2928 | 0.0065 0.0000 0.2405 0.0991 0.0704 0.0000 | Substantially there is not corrosion moderate corrosion mild corrosion |
Result of the test explanation disinfectant of the present invention non-corrosiveness safe in utilization, basic.
7. on-site disinfection test.
With the natural bacteria is index, and test repeats four times, and results averaged sees table 6 for details:
The on-site disinfection test result of table 6 disinfectant of the present invention
| Sterilization objects | Dilution factor | Available iodine content (mg/L) | Time (min) | The average bacterium number of experimental group (cfu/cm 2) | The average bacterium number of control group (cfu/cm 2) | Sterilizing rate (%) |
| The surface, pond | 1/400 | 12.75 | 3 | 3.30×10 2 | 2.12×10 6 | 98.44 |
Result of the test shows that disinfectant of the present invention has good bactericidal effect.
Claims (6)
1. a wide spectrum animal disinfectant mainly is made up of the raw material of following weight portion: 8～20 parts of eicosyl amine oxides, 0.1～0.8 part of iodine, 1～6 part of two octadecane hydroxypropyl quaternary ammonium salt, 1～6 part of solubilizer, 2～8 parts of phosphoric acid.
2. according to the disinfectant of claim 1, it is characterized in that the weight portion of each raw material is: 12 parts of eicosyl amine oxides, 0.5 part of iodine, 3 parts of two octadecane hydroxypropyl quaternary ammonium salts, 3 parts of solubilizer, phosphatase 24 part.
3. according to the disinfectant of claim 1, it is characterized in that: described solubilizer is ethylene glycol, ethanol or water.
4. the purposes of the described arbitrary disinfectant of claim 1～3 in preparation animal oral disinfecting medicine.
5. the purposes of the described arbitrary disinfectant of claim 1～3 in preparation animal intestinal disinfecting drug.
6. the purposes of the described arbitrary disinfectant of claim 1～3 in preparation environment disinfected medicine.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100661024A CN100361584C (en) | 2005-04-20 | 2005-04-20 | Broad-spectrum antiseptics and production thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2005100661024A CN100361584C (en) | 2005-04-20 | 2005-04-20 | Broad-spectrum antiseptics and production thereof |
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| CN1853480A CN1853480A (en) | 2006-11-01 |
| CN100361584C true CN100361584C (en) | 2008-01-16 |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103109861B (en) * | 2011-11-16 | 2015-01-07 | 洛阳惠中兽药有限公司 | Iodine-containing disinfectant |
| CN103766399B (en) * | 2012-10-22 | 2016-08-24 | 洛阳惠中兽药有限公司 | A kind of iodine-containing disinfectant and preparation method thereof |
| CN111937901B (en) * | 2020-09-15 | 2021-06-01 | 四川长宁天然气开发有限责任公司 | Special foamless composite bactericide for shale gas well pipeline and preparation method thereof |
| CN115251092B (en) * | 2022-09-01 | 2023-11-24 | 李忠泽 | Environment-friendly disinfectant capable of rapidly inactivating bacteria and viruses and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252406A (en) * | 1998-10-27 | 2000-05-10 | 王维加 | Ammonium-iodine type complexed iodine disinfectant and its preparation |
| WO2001020988A2 (en) * | 1999-09-22 | 2001-03-29 | Clariant International Ltd. | Disinfectant composition |
| JP2003146953A (en) * | 2001-11-14 | 2003-05-21 | Toagosei Co Ltd | New quaternary ammonium salt compound, method for producing the same and antimicrobial agent containing the same compound |
-
2005
- 2005-04-20 CN CNB2005100661024A patent/CN100361584C/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252406A (en) * | 1998-10-27 | 2000-05-10 | 王维加 | Ammonium-iodine type complexed iodine disinfectant and its preparation |
| WO2001020988A2 (en) * | 1999-09-22 | 2001-03-29 | Clariant International Ltd. | Disinfectant composition |
| JP2003146953A (en) * | 2001-11-14 | 2003-05-21 | Toagosei Co Ltd | New quaternary ammonium salt compound, method for producing the same and antimicrobial agent containing the same compound |
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| CN1853480A (en) | 2006-11-01 |
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