CL2013001403A1 - Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso. - Google Patents
Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso.Info
- Publication number
- CL2013001403A1 CL2013001403A1 CL2013001403A CL2013001403A CL2013001403A1 CL 2013001403 A1 CL2013001403 A1 CL 2013001403A1 CL 2013001403 A CL2013001403 A CL 2013001403A CL 2013001403 A CL2013001403 A CL 2013001403A CL 2013001403 A1 CL2013001403 A1 CL 2013001403A1
- Authority
- CL
- Chile
- Prior art keywords
- encodes
- vector
- nucleic acid
- composition
- production
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
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- Biochemistry (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Cell Biology (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41561410P | 2010-11-19 | 2010-11-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2013001403A1 true CL2013001403A1 (es) | 2014-08-08 |
Family
ID=46084688
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2013001403A CL2013001403A1 (es) | 2010-11-19 | 2013-05-17 | Anticuerpo monoclonal anti-ccl20 o un fragmento de unión del mismo; molecula de acido nucleico que lo codifica; vector; celula huesped; metodo de produccion; composicion que lo comprende; y su uso. |
Country Status (25)
Country | Link |
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US (3) | US8491901B2 (es) |
EP (1) | EP2640744A4 (es) |
JP (3) | JP5996549B2 (es) |
KR (1) | KR101919170B1 (es) |
CN (1) | CN103874707B (es) |
AR (1) | AR084141A1 (es) |
AU (2) | AU2011329647B2 (es) |
BR (1) | BR112013012396A2 (es) |
CA (1) | CA2818548A1 (es) |
CL (1) | CL2013001403A1 (es) |
CO (1) | CO6761352A2 (es) |
CR (1) | CR20130228A (es) |
DO (1) | DOP2013000111A (es) |
EA (1) | EA029419B1 (es) |
IL (1) | IL226383B (es) |
MA (1) | MA34738B1 (es) |
MX (1) | MX361929B (es) |
NZ (1) | NZ611269A (es) |
PE (2) | PE20140633A1 (es) |
PH (1) | PH12013500990A1 (es) |
SG (2) | SG10201509499RA (es) |
TW (1) | TWI589587B (es) |
UA (1) | UA114077C2 (es) |
WO (1) | WO2012068540A2 (es) |
ZA (3) | ZA201303571B (es) |
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SG10201509499RA (en) * | 2010-11-19 | 2015-12-30 | Eisai R&D Man Co Ltd | Neutralizing anti-ccl20 antibodies |
CA2862319C (en) | 2012-02-17 | 2021-11-30 | Seattle Genetics, Inc. | Antibodies to integrin .alpha.v.beta.6 and use of same to treat cancer |
EP2906295A4 (en) * | 2012-10-15 | 2016-06-01 | Oncomed Pharm Inc | METHODS OF TREATING OCULAR DISEASES |
EP3128997B1 (en) | 2014-04-08 | 2020-08-05 | Boston Pharmaceuticals Inc. | Binding molecules specific for il-21 and uses thereof |
KR20170004006A (ko) | 2014-05-21 | 2017-01-10 | 화이자 인코포레이티드 | 암을 치료하기 위한 항-ccr4 항체 및 4-1bb 효능제의 조합 |
MA41480A (fr) * | 2014-10-17 | 2017-12-19 | Glenmark Pharmaceuticals Sa | Anticorps qui se lient au ccr6 et leurs utilisations |
CN107207590A (zh) * | 2014-12-17 | 2017-09-26 | 癌症研究技术有限公司 | 抗cxcl12抗体分子及其用途 |
EP3302527B1 (en) | 2015-06-03 | 2020-01-08 | The Medical College of Wisconsin, Inc. | An engineered ccl20 locked dimer polypeptide |
US11571462B2 (en) | 2015-06-03 | 2023-02-07 | The Medical College Of Wisconsin, Inc. | Engineered CCL20 locked dimer polypeptide |
SG10201912086QA (en) * | 2015-07-14 | 2020-02-27 | Medimmune Llc | Compositions and methods for treating cancer |
WO2017064564A2 (en) * | 2015-10-16 | 2017-04-20 | Glaxosmithkline Intellectual Property Limited | Therapeutic regimens for treating psoriatic arthritis with an anti-ccl20 antibody |
WO2017127390A1 (en) * | 2016-01-21 | 2017-07-27 | The Scripps Research Institute | Synthetic opioid vaccine |
MX378572B (es) | 2016-01-22 | 2025-03-11 | Merck Sharp & Dohme Llc | Anticuerpos anti-factor de la coagulacion xi. |
KR102379580B1 (ko) | 2016-06-14 | 2022-03-29 | 머크 샤프 앤드 돔 코포레이션 | 항응고 인자 xi 항체 |
MX2019005491A (es) * | 2016-11-14 | 2019-08-12 | Dinona | Anticuerpo que enlaza especificamente a cd66c y uso del mismo. |
FR3072779A1 (fr) * | 2017-10-19 | 2019-04-26 | Sinnovial | Procede d'estimation de l'efficacite d'un modulateur de la costimulation des lymphocytes t contre la polyarthrite rhumatoide apres reponse inadequate a une biotherapie |
WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
WO2019094595A2 (en) * | 2017-11-09 | 2019-05-16 | Pinteon Therapeutics Inc. | Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies |
WO2020185952A1 (en) * | 2019-03-11 | 2020-09-17 | xCella Biosciences, Inc. | Cd27-binding antibodies and uses thereof |
CA3159414A1 (en) * | 2019-12-05 | 2021-06-10 | Seagen Inc. | Anti-av.beta.6 antibodies and antibody-drug conjugates |
CN113087795B (zh) * | 2019-12-23 | 2025-06-10 | 上海普铭生物科技有限公司 | 针对趋化因子cx3cl1的抗体及其应用 |
KR20240049361A (ko) * | 2021-08-25 | 2024-04-16 | 아이바이오, 인크. | 항-cd25 항체 |
CN117209603B (zh) * | 2021-12-02 | 2024-02-27 | 北京东方百泰生物科技股份有限公司 | 一种抗tslp的单克隆抗体、其抗原结合片段及其应用 |
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