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CA958314A - Process for the demonstration and determination of reaction components having specific binding affinity for each other - Google Patents

Process for the demonstration and determination of reaction components having specific binding affinity for each other

Info

Publication number
CA958314A
CA958314A CA134,026A CA134026A CA958314A CA 958314 A CA958314 A CA 958314A CA 134026 A CA134026 A CA 134026A CA 958314 A CA958314 A CA 958314A
Authority
CA
Canada
Prior art keywords
demonstration
determination
specific binding
binding affinity
reaction components
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA134,026A
Other versions
CA134026S (en
Inventor
Antonius H.W.M. Schuurs
Bauke K. Van Weemen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzona Inc
Original Assignee
Akzona Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzona Inc filed Critical Akzona Inc
Application granted granted Critical
Publication of CA958314A publication Critical patent/CA958314A/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306Solid-phase reaction mechanisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • G01N33/539Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody involving precipitating reagent, e.g. ammonium sulfate
    • G01N33/541Double or second antibody, i.e. precipitating antibody
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743Steroid hormones
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/971Capture of complex after antigen-antibody reaction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/807Apparatus included in process claim, e.g. physical support structures
    • Y10S436/808Automated or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/815Test for named compound or class of compounds
    • Y10S436/817Steroids or hormones
    • Y10S436/818Human chorionic gonadotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA134,026A 1971-02-10 1972-02-07 Process for the demonstration and determination of reaction components having specific binding affinity for each other Expired CA958314A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL717101728A NL154600B (en) 1971-02-10 1971-02-10 METHOD FOR THE DETERMINATION AND DETERMINATION OF SPECIFIC BINDING PROTEINS AND THEIR CORRESPONDING BINDABLE SUBSTANCES.

Publications (1)

Publication Number Publication Date
CA958314A true CA958314A (en) 1974-11-26

Family

ID=19812444

Family Applications (2)

Application Number Title Priority Date Filing Date
CA134,026A Expired CA958314A (en) 1971-02-10 1972-02-07 Process for the demonstration and determination of reaction components having specific binding affinity for each other
CA303,100A Expired CA1040082B (en) 1971-02-10 1978-05-11 Process for the demonstration and determination of reaction components having specific binding affinity for each other

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA303,100A Expired CA1040082B (en) 1971-02-10 1978-05-11 Process for the demonstration and determination of reaction components having specific binding affinity for each other

Country Status (16)

Country Link
US (1) US3791932A (en)
JP (1) JPS5247011B1 (en)
AU (1) AU468151B2 (en)
BE (1) BE779209A (en)
BR (1) BR7200729D0 (en)
CA (2) CA958314A (en)
CH (1) CH573115A5 (en)
DE (1) DE2206103B2 (en)
DK (1) DK150170C (en)
ES (1) ES399608A1 (en)
FI (1) FI53894C (en)
FR (1) FR2126760A5 (en)
GB (1) GB1363565A (en)
NL (1) NL154600B (en)
SE (1) SE451098B (en)
ZA (1) ZA72548B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31006E (en) * 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other

Families Citing this family (975)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203802A (en) * 1971-05-14 1980-05-20 Syva Company Inhibitable enzyme amplification assay
US3875011A (en) * 1972-11-06 1975-04-01 Syva Co Enzyme immunoassays with glucose-6-phosphate dehydrogenase
US3904367A (en) * 1973-08-15 1975-09-09 Gen Electric Contrast enhancement for immunological film detection
US4039652A (en) * 1973-10-11 1977-08-02 Miles Laboratories, Inc. Column method of immunoassay employing an immobilized binding partner
US3951748A (en) * 1974-11-11 1976-04-20 Medical Products, Inc. Sensitized matrix for detection of disease
SE388694B (en) * 1975-01-27 1976-10-11 Kabi Ab WAY TO PROVIDE AN ANTIGEN EXV IN SAMPLES OF BODY WHEATS, USING POROST BERAR MATERIAL BONDED OR ADSORBING ANTIBODIES
NL7501215A (en) * 1975-02-01 1976-08-03 Akzo Nv METHOD FOR DETERMINING AND DETERMINING AN ANTIGEN OR ANTIBODY.
IN142734B (en) * 1975-04-28 1977-08-20 Miles Lab
USRE32696E (en) * 1975-09-04 1988-06-14 Akzona Incorporated Enzymatic immunological method for determination of antigens and antibodies
US4016043A (en) * 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4642285A (en) * 1975-09-29 1987-02-10 Diamedix Corporation Sandwich EIA for antigen
US4474878A (en) * 1975-09-29 1984-10-02 Cordis Laboratories, Inc. Sandwich EIA for antigen associated with hepatitis
SE7610683L (en) * 1975-09-29 1977-06-10 Cordis Corp METHOD OF DETERMINING THE NERVARON OF AN ANTIGEN ASSOCIATE WITH HEPATITIS
US4116776A (en) * 1976-04-19 1978-09-26 International Radioimmune Systems, Inc. Diagnostic blood test and kit for detecting human chorionic gonadotropin
GB1572220A (en) * 1976-10-07 1980-07-30 Mochida Pharm Co Ltd Immunochemical process of measuring physiologically active substances
GB1549069A (en) * 1976-12-10 1979-08-01 Erba Farmitalia Enzyme linked immunoassay
JPS5399319A (en) * 1977-02-09 1978-08-30 Hidematsu Hirai Novel qualitative and quantitative detecting method and detecting body for antgenic substance
IT1153999B (en) * 1977-03-15 1987-01-21 Snam Progetti COMPOSITION SUITABLE FOR DETERMINING TRIIODOTHYRONIN AND DIAGNOSTIC METHOD USING THE SAME
IL51668A (en) * 1977-03-16 1981-12-31 Israel State Analytical method for the quantitative determination of immunogens and antibodies and a kit therefor
CA1108516A (en) * 1977-11-21 1981-09-08 Stanley E. Charm Antibiotic detection method
US4275149A (en) * 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
NL7804144A (en) * 1978-04-18 1979-10-22 Akzo Nv DEVICE FOR CLORIMETRIC PROVISIONS.
NZ190452A (en) * 1978-05-19 1981-04-24 Becton Dickinson Co Solid phase assay receptor contacted with analyte and then with labeled analyte
JPS54170918U (en) * 1978-05-23 1979-12-03
US4273756A (en) * 1978-07-28 1981-06-16 Abbott Laboratories Immunoassay for class specific antibodies
US4292296A (en) * 1978-09-12 1981-09-29 Baxter Travenol Laboratories, Inc. Diagnostic method
US4240751A (en) * 1978-11-09 1980-12-23 Akzona Incorporated Method and apparatus for specific binding substances
US4374925A (en) * 1978-11-24 1983-02-22 Syva Company Macromolecular environment control in specific receptor assays
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
JPS55116258A (en) * 1979-03-01 1980-09-06 Fuji Photo Film Co Ltd Microimmunoassay method
JPS55116259A (en) * 1979-03-01 1980-09-06 Fuji Photo Film Co Ltd Microimmunoassay method
US4269938A (en) * 1979-03-08 1981-05-26 Eastman Kodak Company Assay of peroxidatively active materials
US4289748A (en) * 1979-05-31 1981-09-15 United States Of America Ultrasensitive enzymatic radioimmunoassay method
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
US4347312A (en) * 1980-03-20 1982-08-31 Research Triangle Institute Detection of antibiotics in milk
JPS56143955A (en) * 1980-04-10 1981-11-10 Fujirebio Inc Method for diagnosis of initial infection of syphilis
AU543007B2 (en) * 1980-04-15 1985-03-28 Technicon Instruments Corportion Agglutination immunoassay
DE3016575A1 (en) * 1980-04-30 1981-11-05 Merck Patent Gmbh, 6100 Darmstadt METHOD FOR THE IMMUNOLOGICAL DETERMINATION OF ENZYMES, MEANS FOR CARRYING OUT THE METHOD AND ITS RELATIONSHIP
US6406920B1 (en) 1980-06-20 2002-06-18 Inverness Medical Switzerland Gmbh Processes and apparatus for carrying out specific binding assays
EP0146654A3 (en) * 1980-06-20 1986-08-20 Unilever Plc Processes and apparatus for carrying out specific binding assays
NL185309C (en) 1980-07-28 1990-03-01 Akzo Nv METHOD FOR DETERMINING ANTIGENS USING TWO OR MORE MONOCLONAL ANTIBODIES AND IMMUNE REAGENTS.
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) * 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4323647A (en) * 1980-10-15 1982-04-06 University Of Miami Steric hindrance enzyme immunoassay
NZ199286A (en) * 1980-12-22 1986-05-09 Commw Serum Lab Commission A method of detecting antibodies or an antigenic or haptenic substance in a sample
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4425438A (en) * 1981-03-13 1984-01-10 Bauman David S Assay method and device
GB2095258B (en) * 1981-03-19 1984-09-05 Janssen Pharmaceutica Nv A bright field light microscopic method of localizing tissue antigens
US4592995A (en) * 1981-03-30 1986-06-03 Dainippon Pharmaceutical Co., Ltd. Reagent for streptococcal anti-esterase assay
US4604365A (en) * 1981-06-02 1986-08-05 Electro-Nucleonics, Inc. Immunoprecipitation assay
JPS57193643U (en) * 1981-06-03 1982-12-08
US4447528A (en) * 1981-08-10 1984-05-08 Corning Glass Works Detecting intrinsic factor blocking site antibody
WO1983000877A1 (en) * 1981-08-31 1983-03-17 Icl Scient Glucose oxidase immunohistochemical detection of antinuclear antibodies
US4452886A (en) * 1981-09-21 1984-06-05 Henry Robert P Novel photon absorbing or emitting polymers and their use as reagents in immunoassay systems
US4446232A (en) * 1981-10-13 1984-05-01 Liotta Lance A Enzyme immunoassay with two-zoned device having bound antigens
US4753875A (en) * 1981-11-02 1988-06-28 Ryan James W Method for assaying proteases with tagged proteinaceous inhibitors
US4506009A (en) * 1982-03-30 1985-03-19 University Of California Heterogeneous immunoassay method
US4469787A (en) * 1982-05-14 1984-09-04 Mallinckrodt Inc. Immunoassay involving soluble complex of second antibody and labeled binding protein
US4503143A (en) * 1982-08-20 1985-03-05 Btc Diagnostics Limited Partnership Enzyme immunoassay with two-part solution of tetramethylbenzidine as chromogen
US4530900A (en) * 1982-09-13 1985-07-23 Seragen Diagnostics Inc. Soluble insoluble polymers in enzymeimmunoassay
FR2550799B1 (en) * 1983-08-17 1986-02-21 Commissariat Energie Atomique COMPOUND MARKED BY AN ENZYME, ITS PREPARATION METHOD AND ITS USE IN ENZYMOIMMUNOLOGY
EP0161247A4 (en) * 1983-11-08 1988-09-19 Quidel Rapid plunger immunoassay method and apparatus.
US4777240A (en) * 1984-03-08 1988-10-11 Scripps Clinic And Research Foundation SV40 expression vector containing HBxAg as an expression marker
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
US4665020A (en) * 1984-05-30 1987-05-12 United States Department Of Energy Flow cytometer measurement of binding assays
US4812395A (en) * 1984-11-05 1989-03-14 E. I. Du Pont De Nemours And Company Method for detecting enzymatic activity using particle agglutination
US4812396A (en) * 1984-11-05 1989-03-14 E. I. Du Pont De Nemours And Company Method for detecting enzymatic activity using particle agglutination
US4713347A (en) * 1985-01-14 1987-12-15 Sensor Diagnostics, Inc. Measurement of ligand/anti-ligand interactions using bulk conductance
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
US4837395A (en) * 1985-05-10 1989-06-06 Syntex (U.S.A.) Inc. Single step heterogeneous assay
US4931385A (en) * 1985-06-24 1990-06-05 Hygeia Sciences, Incorporated Enzyme immunoassays and immunologic reagents
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
CH670709A5 (en) * 1986-04-24 1989-06-30 Univ Moskovsk
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5102788A (en) * 1988-11-21 1992-04-07 Hygeia Sciences, Inc. Immunoassay including lyophilized reactant mixture
US5135863A (en) * 1988-12-23 1992-08-04 Syntex (U.S.A.) Inc. Compositions and methods for determining the presence of amphetamines in a sample suspected of containing amphetamine and/or methamphetamine
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
WO1992020820A1 (en) * 1991-05-15 1992-11-26 Vanderbilt University Method to determine metastatic potential of tumor cells
US5348867A (en) * 1991-11-15 1994-09-20 George Georgiou Expression of proteins on bacterial surface
US5874423A (en) * 1992-09-10 1999-02-23 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Digitalis-like compounds
US6953573B1 (en) 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
WO1995034640A1 (en) * 1994-06-13 1995-12-21 Henry Ford Health System A novel neuronal-neonatal gene: neuronatin
US5698686A (en) 1994-10-20 1997-12-16 Arch Development Corporation Yeast telomerase compositions
US6531277B2 (en) 1994-10-25 2003-03-11 The Curators Of The University Of Missouri Endometriosis-specific secretory protein
US5843673A (en) * 1994-10-25 1998-12-01 Curators Of The University Of Missouri Method of screening for endometriosis
US20030152909A1 (en) * 1994-11-16 2003-08-14 Mitrani Eduardo N. In vitro micro-organs, and uses related thereto
US5777093A (en) * 1995-05-16 1998-07-07 Ramot-University Authority For Applied Research & Industrial Development Ltd. cDNAs associated with ataxia-telangiectasia
US5728807A (en) * 1995-05-16 1998-03-17 Ramot-University Authority For Applied Research And Industrial Development, Ltd. Mutated proteins associated with ataxia-telangiectasia
US5858661A (en) * 1995-05-16 1999-01-12 Ramot-University Authority For Applied Research And Industrial Development Ataxia-telangiectasia gene and its genomic organization
US5807552A (en) * 1995-08-04 1998-09-15 Board Of Regents, The University Of Texas System Compositions for conferring immunogenicity to a substance and uses thereof
US6689757B1 (en) 1996-02-12 2004-02-10 M.L. Laboratories Plc Methods for vaccination and vaccines therefor
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
EP0918845A4 (en) 1996-07-08 2000-08-30 Burstein Lab Inc Cleavable signal element device and method
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US5840322A (en) * 1996-12-19 1998-11-24 Ramot-University Authority For Applied Research & Industrial Devel. Ltd. Anti-oral-microbial adhesion fraction derived from vaccinium
DE69829857T2 (en) * 1997-08-21 2006-02-02 Quark Biotech, Inc., Pleasanton HYPOXY-REGULATED GENES
US6610838B1 (en) 1997-09-10 2003-08-26 Symbicom Aktiebolag P13 antigens from Borrelia
US6284496B1 (en) 1997-10-03 2001-09-04 University Of South Florida DNA vector for determining the presence of out-of-reading-frame mutations
AU748467B2 (en) 1997-10-17 2002-06-06 University Of South Florida Method to diagnose and monitor cellular immune deficiencies
US7687057B2 (en) 1998-01-09 2010-03-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem In vitro micro-organs, and uses related thereto
US20080206206A1 (en) 1998-05-07 2008-08-28 University Of South Florida Bone marrow-derived neuronal cells
US6344443B1 (en) 1998-07-08 2002-02-05 University Of South Florida Peptide antagonists of tumor necrosis factor alpha
AU4994899A (en) 1998-07-13 2000-02-01 University Of South Florida Modulation of the phospholipase a2 pathway as a therapeutic
CA2338401A1 (en) * 1998-07-21 2000-02-03 Burstein Laboratories, Inc Optical disc-based assay devices and methods
DE69836493T2 (en) 1998-07-22 2007-09-06 Syntron Bioresearch, Inc., Carlsbad DEVICE FOR DETERMINING SEVERAL ANALYTES
US6187563B1 (en) 1998-08-07 2001-02-13 Yale University βIV-spectrin-polypeptides and nucleic acids encoding same
CA2344653A1 (en) * 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
CN1230444C (en) 1998-11-16 2005-12-07 德克萨斯州立大学董事会 HIV-specfic T-cell induction
WO2000046349A1 (en) * 1999-02-04 2000-08-10 Technion Research & Development Foundation Ltd. Method and apparatus for maintenance and expansion of hemopoietic stem cells and/or progenitor cells
US6440682B1 (en) * 1999-05-28 2002-08-27 Detroit R&D Inc. Detection of hypertension using immunoreactive metabolic products
US6787318B1 (en) 1999-06-01 2004-09-07 Roskamp Research Institute, Llc Assay for evaluating the therapeutic effectiveness of agents in reducing Alzheimer's disease pathology
US7534605B2 (en) 1999-06-08 2009-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem CD44 polypeptides, polynucleotides encoding same, antibodies directed thereagainst and method of using same for diagnosing and treating inflammatory diseases
CA2435411A1 (en) * 1999-06-25 2001-01-04 Yissum Research Development Company Of The Hebrew University Of Jerusale M Method of inducing angiogenesis by micro-organs
US6875582B1 (en) 1999-08-19 2005-04-05 Omniscience Pharmaceuticals, Inc. Methods and targets of antibiotic resistance
US7101839B1 (en) 1999-08-30 2006-09-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US7811981B2 (en) 1999-08-30 2010-10-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of and compositions for inhibiting the proliferation of mammalian cells
US6998232B1 (en) 1999-09-27 2006-02-14 Quark Biotech, Inc. Methods of diagnosing bladder cancer
US7167615B1 (en) 1999-11-05 2007-01-23 Board Of Regents, The University Of Texas System Resonant waveguide-grating filters and sensors and methods for making and using same
NZ519043A (en) 1999-11-19 2006-12-22 Yissum Res Dev Co Nucleic acid comprising a gene derived from Aspergillus niger that encodes a polypeptide that has a beta-glucosidase catalytic activity
US6544506B2 (en) 2000-01-05 2003-04-08 Yeda Research & Development Co. Ltd. Veto cells effective in preventing graft rejection and devoid of graft versus host potential
AU2001225441A1 (en) * 2000-01-24 2001-07-31 Agricultural Research Organization The Volcani Center Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
CA2404489A1 (en) 2000-03-27 2001-10-04 Technion Research And Development Foundation Ltd. Single chain class i major histo-compatibility complexes, constructs encoding same and methods of generating same
US20040191260A1 (en) * 2003-03-26 2004-09-30 Technion Research & Development Foundation Ltd. Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
IL135884A (en) * 2000-04-30 2005-08-31 Yissum Res Dev Co Method for measuring non-transferrin bound iron
HUP0300810A2 (en) 2000-07-20 2003-08-28 M.G.V.S. Ltd. Artifical vascular grafts, and methods of producing and using same
US20040037828A1 (en) 2002-07-09 2004-02-26 Bar-Ilan University Methods and pharmaceutical compositions for healing wounds
US20030114410A1 (en) * 2000-08-08 2003-06-19 Technion Research And Development Foundation Ltd. Pharmaceutical compositions and methods useful for modulating angiogenesis and inhibiting metastasis and tumor fibrosis
ATE493147T1 (en) 2000-08-08 2011-01-15 Technion Res & Dev Foundation PHARMACEUTICAL COMPOSITIONS AND METHODS USEFUL FOR TREATING CANCER OR LIVER FIBROSIS
EP1683874A3 (en) 2000-08-29 2006-10-11 YEDA RESEARCH AND DEVELOPMENT Co. LTD. Methods of isolating genes encoding proteins of specific function and of screening for pharmaceutically active agents
US20070281037A9 (en) * 2000-09-28 2007-12-06 Nanocyte Inc. Sterile preparations and compositions including stinging capsules and methods of producing and using same
AU2001295850A1 (en) * 2000-09-28 2002-04-08 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
US7632522B2 (en) * 2000-09-28 2009-12-15 Nanocyte Inc. Use of stinging cells/capsules for the delivery of active agents to keratinous substances
EP1343894A4 (en) * 2000-11-02 2005-05-04 Univ Singapore AOPB GENE, PROTEIN, HOMOLOGY, FRAGMENTS AND VARIANTS THEREOF AND THEIR USE IN CELL SURFACE PRESENTATION
US8071740B2 (en) 2000-11-17 2011-12-06 Vascular Biogenics Ltd. Promoters exhibiting endothelial cell specificity and methods of using same for regulation of angiogenesis
KR100869814B1 (en) 2000-11-17 2008-11-25 바스큘라 바이오제닉스 리미티드 Promoters showing endothelial specificity and methods of using the same
CA2429817C (en) 2000-11-24 2013-02-12 Vascular Biogenics Ltd. Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis
US20020172980A1 (en) * 2000-11-27 2002-11-21 Phan Brigitte Chau Methods for decreasing non-specific binding of beads in dual bead assays including related optical biodiscs and disc drive systems
US20030003464A1 (en) * 2000-11-27 2003-01-02 Phan Brigitte C. Dual bead assays including optical biodiscs and methods relating thereto
US20040248093A1 (en) * 2000-11-27 2004-12-09 Coombs James Howard Magneto-optical bio-discs and systems including related methods
EP1337152A4 (en) * 2000-11-30 2004-08-11 Yeda Res & Dev METHOD FOR USING BREEDED NON-GVHD INDUCING T-LYMPHOCYTES FOR TREATING DISEASES
CA2430473A1 (en) 2000-11-30 2002-06-06 Molecular Skincare Limited Diagnosis and treatment of disease
WO2002047535A2 (en) * 2000-12-14 2002-06-20 Nyxis Neurotherapies, Inc. High throughput assay to detect inhibitors of the map kinase pathway
US7087395B1 (en) 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
AU2002230061A1 (en) * 2001-01-31 2002-08-12 Tolaren Induction of tolerance by apoptotic and/or necrotic cells
US20050202098A1 (en) * 2001-01-31 2005-09-15 Tolaren Disease therapy using dying or dead cells
US20030003454A1 (en) 2001-03-23 2003-01-02 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Methods and kits for determining a risk to develop cancer, for evaluating an effectiveness and dosage of cancer therapy and for correlating between an activity of a DNA repair enzyme and a cancer
EP1493014A2 (en) 2001-04-11 2005-01-05 Burstein Technologies, Inc. Multi-parameter assays including analysis discs and methods relating thereto
US6770622B2 (en) 2001-06-08 2004-08-03 Gary A. Jarvis N-terminally truncated galectin-3 for use in treating cancer
MXPA04000397A (en) * 2001-07-19 2004-03-18 Yissum Res Dev Co Polypeptides having carotenoids isomerase catalytic activity, nucleic acids encoding same and uses thereof.
AU2002330724A1 (en) 2001-08-16 2003-03-10 Bar Ilan University Diagnosis, prevention and treatment of cancer
US20040136972A1 (en) 2001-09-07 2004-07-15 Yeda Research And Development Co. Ltd. Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
US7138144B2 (en) * 2001-09-07 2006-11-21 Nadir Askenasy Method of inducing immune tolerance via blood/lymph flow-restricted bone marrow transplantation
EP1436313B1 (en) 2001-10-19 2010-09-22 Vascular Biogenics Ltd. Polynucleotide constructs, pharmaceutical compositions and methods for targeted downregulation of angiogenesis and anticancer therapy
AUPR842501A0 (en) * 2001-10-23 2001-11-15 Epipop Pty Ltd A method for identification and development of therapeutic agents
US6867005B2 (en) 2001-10-24 2005-03-15 Beckman Coulter, Inc. Method and apparatus for increasing the dynamic range and accuracy of binding assays
US6696254B2 (en) 2001-11-21 2004-02-24 Kimberly-Clark Worldwide, Inc. Detection and identification of enteric bacteria
WO2003048298A2 (en) * 2001-12-05 2003-06-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nanoparticles containing polymeric nucleic acid homologs, pharmaceutical compositions and articles of manufacture containing same and methods of use thereof
US20050085432A1 (en) * 2001-12-26 2005-04-21 Aviva Lapidot Methods of using conjugates of saccharides and acetamidino or guanidino compounds for treating bacterial infections
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
EP1465982A4 (en) * 2002-01-25 2006-06-07 Gamida Cell Ltd Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
US20040052928A1 (en) * 2002-09-06 2004-03-18 Ehud Gazit Peptides and methods using same for diagnosing and treating amyloid-associated diseases
WO2005000193A2 (en) * 2003-06-30 2005-01-06 Tel Aviv University Future Technology Development L.P. Peptides antibodies directed thereagainst and methods using same for diagnosing and treating amyloid-associated diseases
US7781396B2 (en) * 2002-01-31 2010-08-24 Tel Aviv University Future Technology Development L.P. Peptides directed for diagnosis and treatment of amyloid-associated disease
US6992176B2 (en) 2002-02-13 2006-01-31 Technion Research & Development Foundation Ltd. Antibody having a T-cell receptor-like specificity, yet higher affinity, and the use of same in the detection and treatment of cancer, viral infection and autoimmune disease
JP2005533486A (en) * 2002-02-20 2005-11-10 ダイアックス、コープ MHC-peptide complex binding ligand
SI3031910T1 (en) 2002-02-21 2018-05-31 Institute Of Virology Slovak Academy Of Sciences Mn/ca ix-specific monoclonal antibodies generated from mn/ca ix-deficient mice and methods of use
JP2005520511A (en) * 2002-03-18 2005-07-14 ガミダ セル リミテッド Methods for inducing differentiation in ex vivo expanded stem cells
DE60320793D1 (en) * 2002-03-26 2008-06-19 Nanocyte Inc NURSES CELLS WITH EXPRESSION OF AN EXOGENOUS POLYNUCLEOTIDE THAT CODES A THERAPEUTIC, DIAGNOSTIC OR COSMETIC AGENT, AND CAPSULES USED THEREOF FOR USE, COMPOSITIONS AND EQUIPMENT OR APPARATUS, TO AMETIC MEDIUM IN A TISSUE
US8936914B2 (en) * 2002-04-16 2015-01-20 The Regents Of The University Of California Methods of renal cell carcinoma prognosis and treatment selection with carbonic anhydrase IX
US20040121442A1 (en) * 2002-05-05 2004-06-24 Ilan Chet Fungal chitinase, polynucleotide sequences encoding same, promoters of same, and uses thereof
EP1534345A4 (en) * 2002-07-12 2012-03-21 Yissum Res Dev Co Method and device for inducing biological processes by micro-organs
AU2003247143B2 (en) 2002-08-01 2009-07-16 Yeda Research And Development Co. Ltd. Method and composition for protecting neuronal tissue from damage induced by elevated glutamate levels
JP4892705B2 (en) 2002-08-20 2012-03-07 オプサニテクス エルエルシー Lectin compositions and methods for modulating an immune response to an antigen
US7267981B2 (en) 2002-10-07 2007-09-11 Technion Research & Development Foundation Ltd. Human foreskin fibroblasts for culturing ES cells
WO2004037204A2 (en) * 2002-10-25 2004-05-06 University Of South Florida Methods and compounds for disruption of cd40r/cd40l signaling in the treatment of alzheimer's disease
CA2504512A1 (en) 2002-10-30 2004-05-13 Yissum Research Development Company Of The Hebrew University Of Jerusalem Molecules and methods using same for measuring non-transferrin bound iron
US20050054097A1 (en) * 2002-11-17 2005-03-10 Tony Peled EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
US7947499B2 (en) * 2002-11-29 2011-05-24 Technion Research & Development Foundation Ltd. Method of dynamically culturing embryonic stem cells
US7491699B2 (en) * 2002-12-09 2009-02-17 Ramot At Tel Aviv University Ltd. Peptide nanostructures and methods of generating and using the same
EP2338896B1 (en) 2002-12-12 2015-02-11 R.B.T. (Rakuto Bio Technologies) Ltd. Use of lignin peroxidase in skin and hair lightening
WO2004055155A2 (en) 2002-12-16 2004-07-01 Technion Research & Development Foundation Ltd. Methods of preparing feeder cells-free, xeno-free human embryonic stem cells and stem cell cultures prepared using same
US7847084B2 (en) 2002-12-20 2010-12-07 Board Of Regents, The University Of Texas System VMP-like sequences of pathogenic Borrelia species and strains
EP1587953B1 (en) 2003-01-02 2012-02-22 Rappaport Family Institute for Research in the Medical Sciences Methods of predicting a benefit of antioxidant therapy for prevention of cardiovascular disease in hyperglycemic patients
EP2058275A1 (en) 2003-01-07 2009-05-13 Ramot at Tel-Aviv University Ltd. Peptide nanostructures encapsulating a foreign material and method of manufacturing same
WO2004106925A2 (en) * 2003-03-03 2004-12-09 Nagaoka & Co.Ltd. Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same
WO2004078991A2 (en) 2003-03-04 2004-09-16 Yeda Research And Development Co. Ltd. Pon polypeptides, polynucleotides encoding same and compositions and methods utilizing same
US20050054103A1 (en) * 2003-03-07 2005-03-10 Tony Peled Expansion of renewable stem cell populations using modulators of PI 3-kinase
US8017113B2 (en) 2003-03-12 2011-09-13 Rappaport Family Institute For Research In The Medical Sciences Compositions and methods for diagnosing and treating an inflammation
US7294701B2 (en) * 2003-04-02 2007-11-13 Technion Research & Development Foundation Ltd. Antibody fragment capable of modulating multidrug resistance and compositions and kits and methods using same
EP1610678B1 (en) 2003-04-04 2011-07-27 Yeda Research And Development Co., Ltd. Antibodies for inhibiting the activity of mmp-2 and mmp-9
US8252588B2 (en) 2003-04-08 2012-08-28 Yeda Research And Development Co. Ltd. Stem cells having increased sensitivity to SDF-1 and methods of generating and using same
FR2853551B1 (en) 2003-04-09 2006-08-04 Lab Francais Du Fractionnement STABILIZING FORMULATION FOR IMMUNOGLOBULIN G COMPOSITIONS IN LIQUID FORM AND LYOPHILIZED FORM
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
CN1820020B (en) * 2003-05-06 2010-04-28 技术持有有限公司 SARS-coronavirus virus-like particles and methods of use
BRPI0411182B1 (en) 2003-05-22 2019-08-20 Evogene Ltd. METHOD FOR INCREASING TOLERANCE OF A SALT STRESS PLANT AND NUCLEIC ACID CONSTRUCTION
AU2005234725B2 (en) 2003-05-22 2012-02-23 Evogene Ltd. Methods of Increasing Abiotic Stress Tolerance and/or Biomass in Plants and Plants Generated Thereby
US7554007B2 (en) 2003-05-22 2009-06-30 Evogene Ltd. Methods of increasing abiotic stress tolerance and/or biomass in plants
WO2005032455A2 (en) 2003-05-23 2005-04-14 Board Of Regents Combinatorially selected phosphorodithioate aptamer targeting ap-1
US20050020499A1 (en) * 2003-05-27 2005-01-27 Bar Ilan University Methods of attenuating cocaine seeking behavior employing glial cell-derived neurotrophic factor (GDNF) and pharmaceutical compositions and articles of manufacture suited for use in practice of the method
US8129514B2 (en) * 2003-06-19 2012-03-06 Evogene Ltd. Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
EP1636333A4 (en) * 2003-06-19 2007-10-24 Evogene Ltd Nucleotide sequences for regulating gene expression in plant trichomes and constructs and methods utilizing same
CA2542984A1 (en) * 2003-07-07 2005-01-27 David H. Wagner Methods for predicting development of auto-immune diseases and treatment of same
MXPA06001722A (en) * 2003-08-14 2006-05-19 Bio Balance Corp Bacterial strains, compositions including same and probiotic use thereof.
WO2005031362A2 (en) 2003-10-02 2005-04-07 Ramot At Tel Aviv University Ltd. Novel antibacterial agents and methods of identifying and utilizing same
IL158287A0 (en) 2003-10-07 2004-05-12 Yeda Res & Dev Antibodies to nik, their preparation and use
WO2005033145A1 (en) 2003-10-07 2005-04-14 Yeda Research And Development Co. Ltd. Antibodies to nik, their preparation and use
EP1678294A1 (en) * 2003-10-23 2006-07-12 Pfizer Products Inc. Vaccine for periodontal disease
WO2005044855A2 (en) 2003-11-04 2005-05-19 Chiron Corporation Use of antagonist anti-cd40 monoclonal antibodies for treatment of multiple myeloma
PT1682180E (en) 2003-11-04 2010-02-10 Novartis Vaccines & Diagnostic Antagonist anti-cd40 monoclonal antibodies and methods for their use
KR20070028295A (en) 2003-11-04 2007-03-12 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 Use of antagonist anti-CD40 antibodies for the treatment of chronic lymphocytic leukemia
PL1680141T3 (en) 2003-11-04 2011-04-29 Novartis Vaccines & Diagnostics Inc Methods of therapy for solid tumors expressing the cd40 cell-surface antigen
US8034340B2 (en) 2003-11-30 2011-10-11 Yeda Research And Development Ltd. Method for treating an immune disorder by decreasing NIK-SIVA complex formation
WO2005059100A2 (en) * 2003-12-12 2005-06-30 New York University Methods and compositions relating to cystatin c
US20100221233A1 (en) * 2003-12-15 2010-09-02 University Of South Florida Compositions and methods for enhancing neuroprotection via administration of stem cells and blood brain barrier permeabilizers
WO2005061018A1 (en) 2003-12-22 2005-07-07 Regentis Biomaterials Ltd. Matrix comprising naturally-occurring protein backbone
US8007847B2 (en) * 2004-01-13 2011-08-30 Eytan Biderman Feeding formula appliance
US7423139B2 (en) * 2004-01-20 2008-09-09 Insight Biopharmaceuticals Ltd. High level expression of recombinant human erythropoietin having a modified 5′-UTR
WO2005071058A2 (en) * 2004-01-27 2005-08-04 Compugen Ltd. Methods and systems for annotating biomolecular sequences
EP1729793B1 (en) 2004-03-02 2015-07-22 Acceleron Pharma Inc. Alk7 and myostatin inhibitors for muscle wasting disorders
US8352031B2 (en) 2004-03-10 2013-01-08 Impulse Dynamics Nv Protein activity modification
CN101068929A (en) 2004-06-14 2007-11-07 伊沃基因有限公司 Polynucleotides and polypeptides involved in plant fiber development and methods of using same
US8680062B2 (en) * 2004-07-06 2014-03-25 Deliversir Ltd. System for delivering therapeutic agents into living cells and cells nuclei
US20090156471A1 (en) * 2004-07-15 2009-06-18 Ramot At Tel Aviv University Ltd. Use of anti-amyloid agents for treating and typing pathogen infections
EP2295973A1 (en) 2004-09-08 2011-03-16 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by the Secretary, Department of Health and Human Services Compositions and methods for the detection of HIV-1/HIV-2 infection.
EP1799812A4 (en) * 2004-09-16 2009-09-09 Gamida Cell Ltd Methods of ex vivo progenitor and stem cell expansion by co-culture with mesenchymal cells
US8000900B2 (en) 2004-09-21 2011-08-16 Microsoft Corporation Association-based predictions of pathogen characteristics
US20060095241A1 (en) * 2004-10-29 2006-05-04 Microsoft Corporation Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
AU2005288527B9 (en) * 2004-09-29 2011-07-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Recombinant human T2 RNase and uses thereof
EP2816117B1 (en) 2004-09-29 2016-11-30 Collplant Ltd. Collagen producing plants and methods of generating and using same
WO2006040765A1 (en) * 2004-10-12 2006-04-20 Closed Loop Therapies Ltd. Methods and implantable devices for treating supraventricular arrhythmias
US8478535B2 (en) 2004-10-29 2013-07-02 Microsoft Corporation Systems and methods that utilize machine learning algorithms to facilitate assembly of aids vaccine cocktails
EP1809765A2 (en) * 2004-11-04 2007-07-25 Roche Diagnostics GmbH Classification of acute myeloid leukemia
US7842794B2 (en) 2004-12-17 2010-11-30 Roche Molecular Systems, Inc. Reagents and methods for detecting Neisseria gonorrhoeae
US20060134680A1 (en) * 2004-12-22 2006-06-22 Alexander Kotlyar Homogeneous populations of nucleic acids, methods of synthesyzing same and uses thereof
EP1844403A4 (en) * 2005-01-16 2010-06-23 Zlango Ltd ICONIC COMMUNICATION
WO2006075335A2 (en) * 2005-01-16 2006-07-20 Zlango Ltd. Communications network system and methods for using same
US8019818B2 (en) * 2005-01-18 2011-09-13 Zlango Ltd. Communications network system and methods for using same
EP1843850B1 (en) 2005-01-31 2015-11-18 Realbio Technologies Ltd. Multistep reaction lateral flow capillary device
EP1865935B1 (en) 2005-02-17 2011-06-08 Hadasit Medical Research Services and Development Ltd. Bisphosphonates for treating endometriosis
JP5432455B2 (en) 2005-02-25 2014-03-05 ザ ステート オブ イスラエル、ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント、アグリカルチュラル リサーチ オーガナイゼイション、(エー.アール.オー.)、ボルカニ センター Fruit cell culture extract for inflammation treatment
US7695927B2 (en) * 2005-03-18 2010-04-13 Detroit R & D Detection of hypertension using glucuronidated metabolic products
US20090068207A1 (en) * 2005-04-15 2009-03-12 Vascular Biogenics Ltd. Compositions Containing Beta 2-Glycoprotein I-Derived Peptides for the Prevention and/or Treatment of Vascular Disease
US8834862B2 (en) * 2005-04-19 2014-09-16 Nanocyte Inc. Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent
PT1889065E (en) 2005-05-18 2013-09-27 Novartis Ag Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component
EP2279726A3 (en) 2005-05-26 2012-06-20 Biorest Ltd. Compositions and methods using same for delivering agents into a target organ protected by a blood barrier
ES2524996T3 (en) 2005-06-16 2014-12-16 Ramot At Tel Aviv University Ltd. Isolated cells and populations that comprise them for the treatment of CNS diseases
US20070225242A1 (en) * 2005-06-21 2007-09-27 The Board Of Trustees Of The Leland Stanford Junior University Method and composition for treating and preventing tumor metastasis in vivo
US20060292559A1 (en) * 2005-06-23 2006-12-28 Beckman Coulter, Inc. Cell-based microarrays, and methods for their preparation and use
EP2487182B1 (en) 2005-07-07 2019-10-23 FULCRUM SP Ltd. Sp1 polypeptides, modified sp1 polypeptides and uses thereof
JP5383186B2 (en) 2005-07-07 2014-01-08 イッサム リサーチ ディベロプメント カンパニー オブ ザ ヘブリュー ユニバーシティ オブ エルサレム リミテッド Nucleic acid agents that down-regulate H19 and methods of using the same
CA2615218A1 (en) 2005-07-18 2007-01-25 Protalix Ltd. Mucosal or enteral administration of biologically active macromolecules
JP5017269B2 (en) 2005-07-26 2012-09-05 ユニヴァーシティ オブ メディシン アンド デンティストリ オブ ニュージャーシィ Antibody profile specific to tuberculosis
EP1945257A4 (en) * 2005-08-08 2009-05-06 Onconon Llc Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
EP1928479B1 (en) 2005-08-24 2016-06-08 Yeda Research And Development Co., Ltd. Universal donor-derived tolerogenic cells for inducing non-syngeneic transplantation tolerance
EP3354723B1 (en) 2005-08-29 2023-12-13 Technion Research & Development Foundation Ltd. Media for culturing stem cells
EP1926814B1 (en) 2005-09-22 2010-04-28 Yissum Research Development Company, of The Hebrew University of Jerusalem Nucleic acid constructs, pharmaceutical compositions and methods of using same for treating cancer
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
AU2006307457B2 (en) 2005-10-24 2012-03-22 Evogene Ltd. Isolated polypeptides, polynucleotides encoding same, transgenic plants expressing same and methods of using same
US8846393B2 (en) 2005-11-29 2014-09-30 Gamida-Cell Ltd. Methods of improving stem cell homing and engraftment
BRPI0620523A2 (en) 2005-11-29 2011-11-16 Gamida Cell Ltd method of increasing implant potential and cell attraction, method of preparing cells for transplantation in a subject, cell population and pharmaceutical composition
WO2007080559A2 (en) 2006-01-16 2007-07-19 Zlango Ltd. Iconic communication
EP2368569A3 (en) 2006-01-18 2012-05-02 University Of Chicago Compositions and methods related to staphylococcal bacterium proteins
US10221228B2 (en) 2006-02-03 2019-03-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US8759292B2 (en) 2006-02-03 2014-06-24 Prolor Biotech, Llc Long-acting coagulation factors and methods of producing same
US8048849B2 (en) 2006-02-03 2011-11-01 Modigene, Inc. Long-acting polypeptides and methods of producing same
US8946155B2 (en) 2006-02-03 2015-02-03 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US9458444B2 (en) 2006-02-03 2016-10-04 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US10351615B2 (en) 2006-02-03 2019-07-16 Opko Biologics Ltd. Methods of treatment with long-acting growth hormone
US8450269B2 (en) 2006-02-03 2013-05-28 Prolor Biotech Ltd. Long-acting growth hormone and methods of producing same
US7553941B2 (en) 2006-02-03 2009-06-30 Modigene Inc Long-acting polypeptides and methods of producing same
US8476234B2 (en) 2006-02-03 2013-07-02 Prolor Biotech Inc. Long-acting coagulation factors and methods of producing same
US9249407B2 (en) 2006-02-03 2016-02-02 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
US20140113860A1 (en) 2006-02-03 2014-04-24 Prolor Biotech Ltd. Long-acting polypeptides and methods of producing and administering same
US8048848B2 (en) 2006-02-03 2011-11-01 Prolor Biotech Ltd. Long-acting interferons and derivatives thereof and methods thereof
US20150038413A1 (en) 2006-02-03 2015-02-05 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
WO2007091254A1 (en) 2006-02-06 2007-08-16 Rappaport Family Institute For Research In The Medical Sciences Methods and kit for diagnosing t1dm
CA2641954C (en) 2006-03-06 2016-04-26 Zetiq Technologies Ltd. Methods and compositions for identifying a cell phenotype
AU2007228341B2 (en) 2006-03-23 2013-10-17 Pluri Biotech Ltd Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US20090226909A1 (en) 2006-03-28 2009-09-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for Determining Predisposition to Warfarin Resistance
WO2007118214A2 (en) * 2006-04-07 2007-10-18 The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services Antibody compositions and methods for treatment of neoplastic disease
AR060487A1 (en) 2006-04-21 2008-06-18 Xoma Technology Ltd PHARMACEUTICAL COMPOSITIONS OF ANTI-BODY ANTAGONISTS ANTI-CD40
US7977457B2 (en) * 2006-05-19 2011-07-12 Teva Pharmaceutical Industries Ltd. Fusion proteins, uses thereof and processes for producing same
US20070281883A1 (en) * 2006-06-05 2007-12-06 Hanna Rosenfeld Development of follicle stimulating hormone agonists and antagonists in fish
WO2008010228A2 (en) 2006-07-20 2008-01-24 Yeda Research And Development Co. Ltd. Photosyntheticorganisms and compositions and methods of generating same
EP2064319B1 (en) 2006-08-28 2017-02-22 Yeda Research and Development Co. Ltd. Methods of generating glial and neuronal cells and use of same for the treatment of medical conditions of the cns
KR20090078776A (en) * 2006-09-08 2009-07-20 위스콘신 얼럼나이 리서어치 화운데이션 Antibody Assay for Para-TB
US7888059B2 (en) * 2006-10-05 2011-02-15 Yeda Research And Development Co. Ltd. Highly purified and stabilized Na,K-ATPase isoforms and methods of producing same
ES2426754T3 (en) 2006-10-05 2013-10-25 Technion Research & Development Foundation Ltd. Microtubes and methods to produce them
MX2009006660A (en) 2006-12-20 2009-08-20 Evogene Ltd Polynucleotides and polypeptides involved in plant fiber development and methods of using same.
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
WO2008087642A2 (en) * 2007-01-16 2008-07-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem Nucleic acid constructs and methods for specific silencing of h19
US20100196403A1 (en) * 2007-01-29 2010-08-05 Jacob Hochman Antibody conjugates for circumventing multi-drug resistance
EP2117616A2 (en) 2007-01-31 2009-11-18 Technion Research & Development Foundation Ltd. Electrospun scaffolds and methods of generating and using same
WO2008093342A2 (en) 2007-02-01 2008-08-07 Technion Research & Development Foundation Ltd. Albumin fibers and fabrics and methods of generating and using same
JP5377330B2 (en) 2007-02-02 2013-12-25 ベイラー リサーチ インスティテュート Vaccine based on targeting of antigen to DCIR expressed on antigen presenting cells
TWI422594B (en) 2007-02-02 2014-01-11 Baylor Res Inst Agent for presenting cells via a dendritic cell asialoglycoprotein receptor (DC-ASGPR)
KR20090114425A (en) 2007-02-02 2009-11-03 베일러 리서치 인스티튜트 Multivariable Antigen Complexed with Targeted Humanized Monoclonal Antibodies
MX2009008918A (en) * 2007-02-23 2009-09-14 Baylor Res Inst Activation of human antigen-presenting cells through clec-6.
NZ579257A (en) * 2007-02-23 2011-05-27 Baylor Res Inst Activation of human antigen-presenting cells through dendritic cell lectin-like oxidized ldl receptor-1 (lox-1)
KR20090114466A (en) 2007-02-23 2009-11-03 베일러 리서치 인스티튜트 Therapeutic Application of Human Antigen Presenter Cell Activation via Dextin-1
EP2839839B1 (en) 2007-02-28 2018-01-17 Yeda Research And Development Company Limited Nuclear targeting sequences
CA2682093A1 (en) 2007-03-29 2008-10-09 Technion Research & Development Foundation Ltd. Antibodies, methods and kits for diagnosing and treating melanoma
KR20100015774A (en) 2007-04-02 2010-02-12 라모트 앳 텔-아비브 유니버시티 리미티드 Methods of detecting cancer cells and use of same for diagnosing and monitoring treatment of the disease
EP2154946B1 (en) 2007-04-09 2013-06-05 Evogene Ltd. Polynucleotides, polypeptides and methods for increasing oil content, growth rate and biomass of plants
US9156865B2 (en) 2007-04-23 2015-10-13 Deliversir Ltd System for delivering therapeutic agents into living cells and cells nuclei
WO2008129548A2 (en) * 2007-04-23 2008-10-30 Segev Laboratories Limited A system for delivering therapeutic agents into living cells and cells nuclei
WO2014064687A1 (en) 2012-10-22 2014-05-01 Deliversir Ltd A system for delivering therapeutic agents into living cells and cells nuclei
US9556210B2 (en) 2007-04-23 2017-01-31 Sabag-Rfa Ltd. System for delivering therapeutic agents into living cells and cells nuclei
EP2152905B1 (en) 2007-05-01 2015-12-02 Tel Hashomer Medical Research Infrastructure and Services Ltd. Methods and kits for detecting fetal cells in the maternal blood
GB2462048B (en) 2007-05-03 2012-03-21 Agency Science Tech & Res Antibodies binding to an intracellular prl-1 or prl-3 polypeptide
JP2010525833A (en) 2007-05-07 2010-07-29 プロタリクス リミテッド Large-scale disposable bioreactor
ATE540115T1 (en) 2007-07-11 2012-01-15 Yeda Res & Dev NUCLEIC ACID CONSTRUCT SYSTEMS WITH CAPABILITY TO DIAGNOSE OR TREAT A CELL CONDITION
IL184627A0 (en) 2007-07-15 2008-12-29 Technion Res & Dev Foundation Agents for diagnosing and modulating metastasis and fibrosis as well as inflammation in a mammalian tissue
WO2009010968A2 (en) 2007-07-15 2009-01-22 Yitzchak Hillman Disease treatment via antimicrobial peptides or their inhibitors
US8686227B2 (en) 2007-07-24 2014-04-01 Evogene Ltd. Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance and/or biomass and/or yield in plants expressing same
PT2537529T (en) 2007-08-02 2018-12-12 Gilead Biologics Inc Loxl2 inhibitory antibodies and uses thereof
WO2009022328A2 (en) 2007-08-15 2009-02-19 Yeda Research And Development Co. Ltd. Regulators of mmp-9 and uses therof
EP2195650B1 (en) 2007-09-12 2016-07-06 Yeda Research And Development Company Ltd. Methods of treating tumors in immune-privileged sites
US20090068669A1 (en) * 2007-09-12 2009-03-12 Elias Georges Slc9a3r1 directed diagnostics for neoplastic disease
KR20140107677A (en) 2007-09-19 2014-09-04 플루리스템 리미티드 Adherent cells from adipose or placenta tissues and use thereof in therapy
CA2702655A1 (en) 2007-10-19 2009-04-23 Rappaport Family Institute For Research In The Medical Sciences Compositions comprising semaphorins for the treatment of angiogenesis related diseases and methods of selection thereof
WO2009059328A2 (en) * 2007-11-02 2009-05-07 The Johns Hopkins University Multi- component l2 vaccine for prevention of human papillomavirus infection
US8431158B2 (en) 2007-11-26 2013-04-30 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions comprising fibrous polypeptides and polysaccharides
US20110119791A1 (en) 2007-12-27 2011-05-19 Evogene Ltd. Isolated polypeptides, polynucleotides useful for modifying water user efficiency, fertilizer use efficiency, biotic/abiotic stress tolerance, yield and biomass in plants
US20090233295A1 (en) * 2008-01-29 2009-09-17 Elias Georges Trim59 directed diagnostics for neoplastic disease
CA2713667A1 (en) * 2008-01-31 2009-08-06 Compugen Ltd. Cd55 isoform and uses therof in cancer detection, monitoring and therapy
ES2483465T3 (en) 2008-02-21 2014-08-06 Technion Research And Development Foundation, Ltd. Use of electro-spinning microtubes to deliver a drug
WO2009117462A1 (en) * 2008-03-18 2009-09-24 Wisconsin Alumini Research Foundation Mycobacterial culture screening test for mycobacterium avium complex bacteria
EP2280731A1 (en) * 2008-04-09 2011-02-09 Technion Research and Development Foundation, Ltd. Anti human immunodeficiency antibodies and uses thereof
US20110033473A1 (en) * 2008-04-09 2011-02-10 Yoram Reiter Anti influenza antibodies and uses thereof
EP2274153B1 (en) * 2008-04-10 2012-07-04 Objet Ltd. System and method for three dimensional model printing
PL2288376T3 (en) 2008-04-18 2016-07-29 Collplant Ltd Methods of generating and using procollagen
CA2721372A1 (en) 2008-04-21 2009-10-29 Danziger Innovations Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
SG176464A1 (en) 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
MX367882B (en) * 2008-05-22 2019-09-10 Evogene Ltd Isolated polynucleotides and polypeptides and methods of using same for increasing plant utility.
CA2725637A1 (en) 2008-05-27 2009-12-03 Pluristem Ltd. Methods of treating inflammatory colon diseases
EP3514229A1 (en) 2008-05-28 2019-07-24 Ramot at Tel-Aviv University Ltd. Mesenchymal stem cells for the treatment of cns diseases
CN102076415B (en) 2008-06-29 2015-06-24 瑞尔比奥技术有限公司 Liquid-transfer device particularly useful as a capturing device in a biological assay process
WO2010007463A1 (en) 2008-07-16 2010-01-21 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
KR101548143B1 (en) 2008-07-16 2015-08-28 베일러 리서치 인스티튜트 HIV vaccine based on targeting maximized Gag and Nef to dendritic cells
EA031177B1 (en) 2008-07-16 2018-11-30 Инститьют Фор Рисерч Ин Байомедисин Human cytomegalovirus neutralizing antibodies and use thereof
EP2313433A2 (en) * 2008-07-25 2011-04-27 Institute for Research in Biomedicine Neutralizing anti-influenza a virus antibodies and uses thereof
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
JP5583667B2 (en) 2008-08-08 2014-09-03 ジェニスフィア・エルエルシー Long-acting DNA dendrimer and method thereof
WO2010016806A1 (en) 2008-08-08 2010-02-11 Agency For Science, Technology And Research (A*Star) Vhz for diagnosis and treatment of cancers
WO2010020941A2 (en) 2008-08-18 2010-02-25 Evogene Ltd. Isolated polypeptides and polynucleotides useful for increasing nitrogen use efficiency, abiotic stress tolerance, yield and biomass in plants
BRPI0913452A2 (en) 2008-09-02 2015-12-01 Pluristem Ltd adherent cells from placental tissue and their use in therapy
US8367392B2 (en) * 2008-09-05 2013-02-05 Transalgae Ltd. Genetic transformation of algal and cyanobacteria cells by microporation
EP2326340A4 (en) 2008-09-11 2013-01-23 Univ Ben Gurion COMPOSITIONS AND METHODS FOR TREATING S. PNEUMONIA INFECTION
RU2535966C2 (en) 2008-09-12 2014-12-20 Криопрашис Криобиоложия Лтда. Cell-based therapy of ischemic tissue
SG10201504623VA (en) 2008-09-24 2015-07-30 Tel Hashomer Medical Res Infrastructure & Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
US20110178024A1 (en) 2008-09-29 2011-07-21 Ben Gurion University Of The Negev Research And Development Authority Amyloid beta-peptides and methods of use thereof
CN102333540B (en) 2008-10-06 2015-04-22 芝加哥大学 Compositions and methods related to bacterial Eap, Emp, and/or Adsa proteins
EP2347014B1 (en) 2008-10-30 2016-09-21 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficieny
US20110229892A1 (en) 2008-11-17 2011-09-22 Yehuda G Assaraf Method for predicting a patient's responsiveness to anti-folate therapy
WO2010058396A1 (en) 2008-11-19 2010-05-27 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. A cd44vra antibody and diagnostic and therapeutic methods using same
WO2010061383A1 (en) 2008-11-26 2010-06-03 Biodalia Microbiological Technologies Ltd. A method of in-situ enrichment of foods with fructan
WO2010064231A1 (en) 2008-12-02 2010-06-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods of analyzing a-i rna editing and nucleic acid constructs capable of same
US20120014927A1 (en) 2008-12-03 2012-01-19 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods and kits for determining predisposition to cancer
US8734759B2 (en) 2008-12-05 2014-05-27 Yeda Research And Development Co. Ltd. Methods of diagnosing and treating motor neuron diseases
WO2010071610A1 (en) 2008-12-19 2010-06-24 Agency For Science, Technology And Research (A*Star) Severe chikungunya biomarkers
WO2010076756A2 (en) 2008-12-29 2010-07-08 Evogene Ltd. Polynucleotides, polypeptides encoded thereby, and methods of using same for increasing abiotic stress tolerance, biomass and/or yield in plants expressing same
SG10201504379VA (en) 2008-12-29 2015-07-30 Tel Hashomer Medical Res Infrastructure & Services Ltd Peptides and compositions for prevention of cell adhesion and methods of using same
EP2376653A2 (en) 2008-12-29 2011-10-19 Yissum Research Development Company of The Hebrew University of Jerusalem Methods of predicting responsiveness to interferon treatment and treating hepatitis c infection
US8455263B2 (en) 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method
WO2010076794A1 (en) 2008-12-31 2010-07-08 Technion Research & Development Foundation Ltd. Method of denitrifying brine and systems capable of same
WO2010080769A2 (en) 2009-01-06 2010-07-15 Arresto Biosciences, Inc. Chemotherapeutic methods and compositions
IL196820A0 (en) 2009-02-01 2009-11-18 Yissum Res Dev Co Devitalized, acellular scaffold matrices derived from micro-organs seeded with various cells
CN102369015A (en) 2009-02-02 2012-03-07 雷蒙特亚特特拉维夫大学有限公司 Peptides, pharmaceutical compositions comprising same and uses thereof
WO2010089707A1 (en) 2009-02-04 2010-08-12 Yeda Research And Development Co. Ltd. Methods and kits for determining sensitivity or resistance of prostate cancer to radiation therapy
WO2010097794A1 (en) 2009-02-26 2010-09-02 Tel Hashomer Medical Research Infrastructure And Services Ltd. Methods of reprogramming renal cells
MX342016B (en) 2009-03-02 2016-09-09 Evogene Ltd Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics.
PL2406279T3 (en) 2009-03-09 2016-07-29 Univ Ramot Compositions for prevention and treatment of neurodegenerative diseases
WO2010103517A1 (en) 2009-03-12 2010-09-16 Rappaport Family Institute For Research In The Medical Sciences Soluble compositions for the treatment of cxcr3-ligand associated diseases
EP2414542B1 (en) 2009-03-30 2017-08-30 Tel HaShomer Medical Research Infrastructure and Services Ltd. Methods of predicting clinical course and treating multiple sclerosis
MX2011010401A (en) 2009-04-01 2012-01-20 Rappaport Family Inst Res In The Medical Sciences A method of regulating proliferation and differentiation of keratinocyes.
KR20170102039A (en) 2009-04-03 2017-09-06 유니버시티 오브 시카고 Compositions and methods related to Protein A (SpA) variants
WO2010116375A1 (en) 2009-04-08 2010-10-14 Yeda Research And Development Co. Ltd. Isolated peptides for regulating apoptosis
KR20180077322A (en) 2009-04-30 2018-07-06 텔 하쇼머 메디컬 리서치 인프라스트럭쳐 앤드 서비시스 리미티드. Anti ceacam1 antibodies and methods of using same
EP2433136B1 (en) 2009-05-19 2015-08-26 Zetiq Technologies Ltd. Kits for and methods of differential staining of cervical cancer cells and/or tissues
WO2010135663A2 (en) 2009-05-21 2010-11-25 The United States Of America , As Represented By The Secretary, Department Of Health And Human Services Compositions and methods for the detection of hiv-1/hiv-2 infection
WO2010137013A1 (en) 2009-05-27 2010-12-02 Ramot At Tel Aviv University Ltd. Crystallized photosystem i units from the pea plant and their use in solid state devices
US20120078163A1 (en) 2009-05-27 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of generating connective tissue
CN102639146A (en) 2009-05-27 2012-08-15 耶达研究及发展有限公司 Proteasome inhibitors and uses thereof
EP2435078A1 (en) 2009-05-28 2012-04-04 Yeda Research and Development Co. Ltd. Methods of treating inflammation
ES2773985T3 (en) 2009-06-10 2020-07-16 Evogene Ltd Isolated polynucleotides and polypeptides, and methods of using them to increase nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and / or tolerance to abiotic stress
IN2012DN00715A (en) 2009-06-24 2015-06-19 Health Corp Rambam
US9663778B2 (en) 2009-07-09 2017-05-30 OPKO Biologies Ltd. Long-acting coagulation factors and methods of producing same
US12203113B2 (en) 2009-07-09 2025-01-21 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
WO2011004379A1 (en) 2009-07-10 2011-01-13 Tel Hashomer Medical Research Infrastructure And Services Ltd. Compositions and methods for treating cancer
CA2768725A1 (en) 2009-07-21 2011-01-27 Tel Hashomer Medical Research Infrastructure And Services Ltd. A method of diagnosing cancer
GB0913442D0 (en) 2009-07-31 2009-09-16 Univ Ramot Cell-targeting nanoparticles comprising polynucleotide agents and uses thereof
WO2011021194A2 (en) 2009-08-17 2011-02-24 Technion Research & Development Foundation Ltd. Pericyte progenitor cells and methods of generating and using same
CA2771774A1 (en) * 2009-08-21 2011-02-24 Gilead Biologics, Inc. In vitro screening assays
CA2771630A1 (en) * 2009-08-21 2011-02-24 Victoria Smith Therapeutic methods and compositions
CN102481311A (en) 2009-08-21 2012-05-30 比欧洛吉科斯公司 Preventing and curing beneficial insect diseases via plant transcribed molecules
EP2467396A4 (en) * 2009-08-21 2012-12-26 Gilead Biologics Inc Catalytic domains from lysyl oxidase and loxl2
WO2011022670A1 (en) * 2009-08-21 2011-02-24 Arresto Biosciences, Inc In vivo screening assays
CN102711839A (en) * 2009-08-21 2012-10-03 吉联亚生物科技有限公司 In vivo screening assays
US9642817B2 (en) 2009-08-27 2017-05-09 Technion Research & Development Foundation Limited Liposomal compositions and uses of same
WO2011030336A1 (en) 2009-09-08 2011-03-17 Ramot At Tel-Aviv University Ltd. Methods of diagnosing amyotrophic lateral sclerosis (als)
WO2011030332A2 (en) 2009-09-08 2011-03-17 Yeda Research And Development Co. Ltd. Methods for hematopoietic precursor mobilization
US20120171213A1 (en) 2009-09-10 2012-07-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating tumors
JP2013505230A (en) 2009-09-17 2013-02-14 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッド Peptides for treating oxidative stress related disorders
US8735124B2 (en) 2009-09-17 2014-05-27 Yeda Research And Development Co. Ltd. Isolated PON1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
WO2011033506A2 (en) 2009-09-17 2011-03-24 Yeda Research And Development Co. Ltd. Isolated pon1 polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
US20110081706A1 (en) * 2009-10-02 2011-04-07 TransAlgae Ltd Method and system for efficient harvesting of microalgae and cyanobacteria
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
CN105368836A (en) 2009-10-14 2016-03-02 耶路撒冷希伯来大学伊森姆研究发展公司 Compositions for controlling varroa mites in bees
EP2488209B1 (en) 2009-10-16 2016-09-28 Rutgers, the State University of New Jersey Method for treating chronic nerve tissue injury using a cell therapy strategy
WO2011048600A1 (en) 2009-10-21 2011-04-28 Danziger Innovations Ltd. Generating genotypic variations in plant genomes by gamete infection
IL201999A (en) 2009-11-08 2017-10-31 Medical Res & Development Fund For Health Services Bnai Zion Medical Center The State Of Israel Knock-out mouse of the mo-1 gene, a gene associated with morbid obesity
WO2011058555A1 (en) 2009-11-12 2011-05-19 Yeda Research And Development Co. Ltd. A method of editing dna in a cell and constructs capable of same
ES2779048T3 (en) 2009-11-12 2020-08-13 Technion Res & Dev Foundation Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
EP2498806B1 (en) 2009-11-12 2014-12-31 Ramot at Tel-Aviv University Ltd. Compositions comprising pedf and uses of same in the treatment and prevention of ovary-related syndromes
WO2011061736A1 (en) 2009-11-17 2011-05-26 Protalix Ltd. Alkaline alpha galactosidase for the treatment of fabry disease
US20130183326A9 (en) 2009-11-20 2013-07-18 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
WO2011064773A1 (en) 2009-11-24 2011-06-03 Collplant Ltd. Method of generating collagen fibers
EP2507362A2 (en) 2009-11-30 2012-10-10 Pluristem Ltd. Adherent cells from placenta and use of same in disease treatment
US9562235B2 (en) 2009-12-06 2017-02-07 A.B. Seeds Ltd. MicroRNA compositions and methods for enhancing plant resistance to abiotic stress
EP2862929B1 (en) 2009-12-09 2017-09-06 Quark Pharmaceuticals, Inc. Compositions and methods for treating diseases, disorders or injury of the CNS
CA2784342C (en) 2009-12-28 2022-11-22 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficiency
EP3184109B1 (en) 2009-12-29 2020-11-18 Gamida-Cell Ltd. Methods for enhancing natural killer cell proliferation and activity
EP2521776B1 (en) 2010-01-05 2016-11-02 Vascular Biogenics Ltd. Methods for use of a specific anti-angiogenic adenoviral agent
SG10201500015TA (en) 2010-01-12 2015-02-27 Vascular Biogenics Ltd Methods of producing adenovirus vectors and viral preparations generated thereby
EP2528949A1 (en) 2010-01-27 2012-12-05 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
RU2015108348A (en) 2010-02-04 2015-07-20 Джилид Байолоджикс, Инк. ANTIBODIES BINDING WITH LYSYLOXIDASE-LIKE ENZYME-2 (LOXL2), AND WAYS OF THEIR APPLICATION
US9410131B2 (en) 2010-02-11 2016-08-09 Yeda Research And Development Co. Ltd. Enzymatic systems for carbon fixation and methods of generating same
US10080799B2 (en) 2010-02-12 2018-09-25 Arizona Board Of Regents On Behalf Of Arizona State University Methods and compositions related to glycoprotein-immunoglobulin fusions
US20130109615A1 (en) 2010-02-24 2013-05-02 Ben Gurion University Of The Negev Research And Development Authority Methods for inhibiting necrosis
WO2011107939A1 (en) 2010-03-01 2011-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of predicting efficacy of an anti-vegfa treatment for solid tumors
WO2011107994A1 (en) 2010-03-04 2011-09-09 Yeda Research And Development Co. Ltd. Methods of measuring protein stability
US9267142B2 (en) 2010-03-08 2016-02-23 Yeda Research And Development Co. Ltd. Recombinant protein production in heterologous systems
PH12012501746A1 (en) 2010-03-08 2022-10-05 Monsanto Technology Llc Polynucleotide molecules for gene regulation in plants
WO2011111050A2 (en) 2010-03-11 2011-09-15 Jacob Edrei Methods of generating hydrogen
EP2556085A2 (en) 2010-04-05 2013-02-13 Bar-Ilan University Protease-activatable pore-forming polypeptides
JP2013523818A (en) 2010-04-05 2013-06-17 ザ・ユニバーシティー・オブ・シカゴ Compositions and methods relating to protein A (SpA) antibodies as enhancers of immune responses
US8927274B2 (en) 2010-04-12 2015-01-06 Technion Research & Development Foundation Limited Populations of pancreatic progenitor cells and methods of isolating and using same
EP2557913B1 (en) 2010-04-12 2016-08-03 Ben Gurion University Of The Negev Research And Development Authority Sulfotransferase of a red microalga and uses thereof
RU2012148398A (en) 2010-04-18 2014-05-27 Иеда Рисеч Энд Девелопмент Ко. Лтд. MOLECULES AND METHODS OF APPLICATION OF MOLECULES FOR THE TREATMENT OF DISEASES ASSOCIATED WITH ErbB / ErbB LIGANDS
EP2563112A4 (en) 2010-04-28 2014-03-05 Evogene Ltd Isolated polynucleotides and polypeptides, and methods of using same for increasing plant yield and/or agricultural characteristics
WO2011138778A2 (en) 2010-05-04 2011-11-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of identifying inhibitors of polypeptides-of-interest
WO2011138785A2 (en) 2010-05-05 2011-11-10 Rappaport Family Institute For Research In The Medical Sciences Use of ccl1 in therapy
IL208820A0 (en) 2010-10-19 2011-01-31 Rachel Teitelbaum Biologic female contraceptives
CA2799307C (en) 2010-05-13 2019-07-02 Tel Hashomer Medical Research Infrastructure And Services Ltd. Isolated populations of adult renal cells and methods of isolating and using same
EP2575859B1 (en) 2010-06-03 2018-09-19 Ramot at Tel Aviv University, Ltd. Methods of treating diabetes and compositions capable of same
US20130316351A1 (en) 2010-06-07 2013-11-28 Osnat Ashur-Fabian Methods and kits for diagnosing conditions related to hypoxia
CN103154022A (en) 2010-06-16 2013-06-12 富途锐基尼以色列有限公司 Pest-resistant plants
US9187787B2 (en) 2010-06-16 2015-11-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of diagnosing and treating cancer
CA2803298C (en) 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
EP2593468B1 (en) 2010-07-12 2020-06-10 The State of Israel, Ministry of Agriculture and Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Isolated polynucleotides and methods and plants using same for regulating plant acidity
CA2805478A1 (en) 2010-07-15 2012-01-19 Technion Research & Development Foundation Ltd. Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides
BR112013000985A2 (en) 2010-07-15 2017-09-05 Technion Res & Dev Foundation ISOLATED HIGH AFFINITY ENTITIES WITH T-CELL RECEPTOR SPECIFICITY WITH RESPECT TO NATIVE MHC CLASS II COMPLEXES AND AUTOANTIGENIC GLUTAMIC ACID DECARBOXYLASE (GAD) PEPTIDES
US10106812B2 (en) 2010-07-15 2018-10-23 Technion Research & Development Foundation Limited Nucleic acid construct for increasing abiotic stress tolerance in plants
US9624469B2 (en) 2010-07-22 2017-04-18 Cellect Biotherapeutics Ltd. Regulatory immune cells with enhanced targeted cell death effect
US9144585B2 (en) 2010-07-27 2015-09-29 Technion Research & Development Foundation Limited Isolated mesenchymal progenitor cells and extracellular matrix produced thereby
JP2013535966A (en) 2010-07-27 2013-09-19 テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド Method for generating induced pluripotent stem cells from keratinocytes derived from extracted hair follicles
WO2012014208A2 (en) 2010-07-27 2012-02-02 Yeda Research And Development Co. Ltd. Methods and systems for assessing clonality of cell cultures
WO2012017439A2 (en) 2010-08-04 2012-02-09 Ramot At Tel-Aviv University Ltd. Methods of treating autoimmune diseases of the central nervous system (cns) and neurodegenerative diseases
SG187830A1 (en) 2010-08-22 2013-03-28 Univ Ramot Induced pluripotent stem cells derived from human pancreatic beta cells
WO2012025925A1 (en) 2010-08-24 2012-03-01 Rappaport Family Institute For Research In The Medical Sciences Methods of improving transplantation using sdf-1alpha
MX2018009863A (en) 2010-08-30 2022-06-14 Evogene Ltd Isolated polynucleotides and polypeptides, and methods of using same for increasing nitrogen use efficiency, yield, growth rate, vigor, biomass, oil content, and/or abiotic stress tolerance.
WO2012032519A2 (en) 2010-09-07 2012-03-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of diagnosing parkinson's disease
DK2614141T3 (en) 2010-09-07 2019-09-09 Technion Res & Dev Foundation PRESENT PROCEDURES AND CULTIVATION MEDIA FOR CULTURING PLURIPOTENT STEM CELLS
EP2613799A1 (en) 2010-09-07 2013-07-17 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Readthrough acetylcholinesterase (ache-r) for treating or preventing parkinson's disease
WO2012032510A1 (en) 2010-09-07 2012-03-15 Yeda Research And Development Co. Ltd. Primers for amplifying dna and methods of selecting same
CN103270050A (en) 2010-09-08 2013-08-28 耶达研究及发展有限公司 An immunosuppressive drug combination for a stable and long term engraftment
KR101788826B1 (en) 2010-09-08 2017-10-20 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 Use of anti third party central memory t cells for anti-leukemia/lymphoma treatment
US9095540B2 (en) 2010-09-09 2015-08-04 The University Of Chicago Methods and compositions involving protective staphylococcal antigens
CN103210082A (en) 2010-09-15 2013-07-17 雷蒙特亚特特拉维夫大学有限公司 Methods of expanding and redifferentiating islet beta cells
WO2012038956A1 (en) 2010-09-20 2012-03-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method of treating neurodegenerative diseases
US8951983B2 (en) 2010-10-17 2015-02-10 Yeda Research And Development Co. Ltd. Methods and compositions for the treatment of insulin-associated medical conditions
WO2012052878A1 (en) 2010-10-19 2012-04-26 Vascular Biogenics Ltd. Isolated polynucleotides and nucleic acid constructs for directing expression of a gene-of-interest in cells
US20130216603A1 (en) 2010-10-27 2013-08-22 Nanocyte (Israel) Ltd. Pharmaceutical compositions and delivery devices comprising stinging cells or capsules
WO2012056455A1 (en) 2010-10-28 2012-05-03 Yeda Research And Development Co. Ltd. Methods of generating antibodies to metalloenzymes
WO2012059922A2 (en) 2010-11-03 2012-05-10 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Transgenic plants with improved saccharification yields and methods of generating same
EP2635105B1 (en) 2010-11-04 2017-12-20 Ben-Gurion University of The Negev Research and Development Authority Acyl-coa: diacylglycerol acyltransferase 1-like gene (ptdgat1) and uses thereof
WO2012066549A1 (en) 2010-11-15 2012-05-24 Ramot At Tel-Aviv University Ltd. Dipeptide analogs for treating conditions associated with amyloid fibril formation
EP2640404B1 (en) 2010-11-17 2017-02-22 Ben Gurion University of The Negev Research and Development Authority T-cell therapy to neurodegenerative diseases
WO2012075111A1 (en) 2010-11-30 2012-06-07 Novartis Ag Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
US9574171B2 (en) 2010-12-02 2017-02-21 Technion Research & Development Foundation Ltd. Methods of generating corneal cells and cell populations comprising same
EP2463382A1 (en) 2010-12-07 2012-06-13 Enterologics, Inc. Method for identifying E. Coli M-17
US9404087B2 (en) 2010-12-15 2016-08-02 Kadimastem Ltd. Insulin producing cells derived from pluripotent stem cells
CA3095614A1 (en) 2010-12-22 2012-06-28 Evogene Ltd. Isolated polynucleotides and polypeptides, and methods of using same for increasing abiotic stress tolerance, yield, growth rate, vigor, biomass, oil content, and/or nitrogen use efficiency of plants
AU2011350620B2 (en) 2010-12-28 2017-03-02 Kamedis Ltd. Plant extracts for the treatment and prevention of infections
BR112013018516B1 (en) 2011-01-20 2023-11-07 Protalix Ltd NUCLEIC ACID EXPRESSION CONSTRUCT, METHOD OF PRODUCING A RECOMBINANT HUMAN ALPHA-GALACTOSIDASE PROTEIN, HUMAN ALFAGALACTOSIDASE PROTEIN, PHARMACEUTICAL COMPOSITION, AND, USE OF A HUMAN ALPHAGALAACTOSIDASE PROTEIN OR A COMPOSITION
WO2012104851A1 (en) 2011-01-31 2012-08-09 Yeda Research And Development Co. Ltd. Methods of diagnosing disease using overlap extension pcr
WO2012114339A1 (en) 2011-02-23 2012-08-30 Rappaport Family Institute For Research In The Medical Sciences High affinity molecules capable of binding a type a plexin receptor and uses of same
EP2492279A1 (en) 2011-02-25 2012-08-29 Laboratorios Del. Dr. Esteve, S.A. Rapid immunogen selection method using lentiviral display
WO2012117406A2 (en) 2011-03-02 2012-09-07 Futuragene Israel Ltd. Bacterial resistant transgenic plants
WO2012117373A1 (en) 2011-03-03 2012-09-07 Ramot At Tel-Aviv University Ltd. Genetically modified muscle cells which express neurotrophic factors
CA2829110C (en) 2011-03-06 2019-01-15 Merck Serono S.A. Low fucose cell lines and uses thereof
WO2012120518A1 (en) 2011-03-08 2012-09-13 Ramot At Tel-Aviv University Ltd. Compositions and methods for diagnosing and treating phenylketonuria (pku)
AU2012227883A1 (en) 2011-03-17 2013-10-24 Ramot At Tel-Aviv University Ltd. Bi- and monospecific, asymmetric antibodies and methods of generating the same
EP2685976B1 (en) 2011-03-17 2017-12-27 Tel HaShomer Medical Research Infrastructure and Services Ltd. Quinolone analogs for treating autoimmune diseases
JP6030114B2 (en) 2011-03-22 2016-11-24 プルリステム リミテッド Methods for treating radiation or chemical injury
EA201391387A1 (en) 2011-03-24 2014-01-30 Неурим Фармасьютикалс (1991) Лтд. NEUROPROTECTIVE PEPTIDES
WO2012131680A2 (en) 2011-03-28 2012-10-04 Yeda Research And Development Co. Ltd. Compositions and methods for treating inflammation
WO2012137202A1 (en) 2011-04-05 2012-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Composition comprising an iron indicator attached to a microparticle and uses of same for quantifying non-transferrin bound iron (ntbi) and cellular labile iron (lci)
EP2694962B1 (en) 2011-04-06 2017-03-01 Ramot at Tel-Aviv University Ltd. Methods of monitoring and analyzing metabolic activity profiles diagnostic and therapeutic uses of same
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
CA2832812C (en) 2011-04-15 2017-12-05 Pluristem Ltd. Methods and systems for harvesting cells
CA2834027C (en) 2011-05-03 2021-12-21 Evogene Ltd. Isolated polynucleotides and polypeptides and methods of using same for increasing plant yield, biomass, growth rate, vigor, oil content, abiotic stress tolerance of plants and nitrogen use efficiency
US9192670B2 (en) 2011-05-04 2015-11-24 Ramot At Tel-Aviv University Ltd. Regulation of amyloid beta molecular composition for the treatment of alzheimer's disease
US8945588B2 (en) 2011-05-06 2015-02-03 The University Of Chicago Methods and compositions involving protective staphylococcal antigens, such as EBH polypeptides
WO2012153333A1 (en) 2011-05-09 2012-11-15 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Regeneration and repair of mesenchymal tissue using amelogenin
WO2012153336A2 (en) 2011-05-12 2012-11-15 Rakuto Bio Technologies Ltd. Methods and device for lightening skin complexion
WO2012156976A1 (en) 2011-05-16 2012-11-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods of producing artemisinin in non-host plants and vectors for use in same
CA2836503C (en) 2011-05-23 2020-09-22 Yeda Research And Development Co. Ltd. Use of akt phosphorylation as a biomarker for prognosing neurodegenerative diseases and treating same
WO2012160526A2 (en) 2011-05-23 2012-11-29 Ofir Menashe Formulations of microorganism comprising particles and uses of same
EP2714719B1 (en) 2011-05-31 2018-12-12 Hutchison Biofilm Medical Solutions Limited Dispersion and detachment of cell aggregates
WO2012164565A1 (en) 2011-06-01 2012-12-06 Yeda Research And Development Co. Ltd. Compositions and methods for downregulating prokaryotic genes
US10166295B2 (en) 2011-06-02 2019-01-01 Opko Biologics Ltd. Pegylated OXM variants
EP2720720B1 (en) 2011-06-14 2018-02-28 Yeda Research and Development Co. Ltd. Combination therapy to prevent dcis formation and progression to breast cancer
WO2012176203A1 (en) 2011-06-23 2012-12-27 Kaiima Bio Agritech Ltd. Common wheat, plants or parts thereof having partially or fully multiplied genome, hybrids and products thereof and methods of generating and using same
MX352338B (en) 2011-07-18 2017-11-17 Inst Res Biomedicine Neutralizing anti-influenza a virus antibodies and uses thereof.
KR20140062468A (en) 2011-07-20 2014-05-23 카이마 바이오 아그리테크 리미티드 Maize plants having a partially or fully multiplied genome and uses thereof
US20130030452A1 (en) 2011-07-27 2013-01-31 Health Corporation - Rambam Devices for surgical applications
ES2732427T3 (en) 2011-08-04 2019-11-22 Yeda Res & Dev MIR-15 Micro-RNA and compositions comprising it for the treatment of diseases associated with corticotropin-releasing hormone
JP6063613B2 (en) 2011-08-09 2017-01-18 イェダ リサーチ アンド デベロップメント カンパニー リミテッド Down-regulation of miR-7 to promote beta cell differentiation and insulin production
CA2844028A1 (en) 2011-08-14 2013-02-21 Kaiima Bio Agritech Ltd. Durum wheat plants having a partially or fully multiplied genome and uses thereof
US9959392B2 (en) 2011-09-07 2018-05-01 Yeda Research And Development Co. Ltd. Olfactory signature and odorant mixture having the same
JP6196620B2 (en) 2011-09-08 2017-09-13 イェダ リサーチ アンド デベロップメント カンパニー リミテッド Anti-third party central memory T cells, methods for their preparation and their use in transplantation and disease treatment
EP2753716B1 (en) 2011-09-08 2017-11-01 Yeda Research and Development Co. Ltd. Novel risk biomarkers for lung cancer
WO2013040049A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
CN104160028A (en) 2011-09-13 2014-11-19 孟山都技术公司 Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
MX343071B (en) 2011-09-13 2016-10-21 Monsanto Technology Llc Methods and compositions for weed control.
WO2013040057A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
WO2013054320A1 (en) 2011-10-11 2013-04-18 Tel Hashomer Medical Research Infrastructure And Services Ltd. Antibodies to carcinoembryonic antigen-related cell adhesion molecule (ceacam)
CN104011068A (en) 2011-10-21 2014-08-27 奥古雷克斯生命科学公司 Antigens derived from citrullinated 14-3-3 and uses thereof in the diagnosis of rheumatoid arthritis
WO2013061328A2 (en) 2011-10-27 2013-05-02 Yeda Research And Development Co. Ltd. Method of treating cancer
WO2013067076A2 (en) 2011-11-03 2013-05-10 Quark Pharmaceuticals, Inc. Methods and compositions for neuroprotection
WO2013070821A1 (en) 2011-11-08 2013-05-16 Quark Pharmaceuticals, Inc. Methods and compositions for treating diseases, disorders or injury of the nervous system
WO2013076729A1 (en) 2011-11-23 2013-05-30 Danziger Dan Flower Farm Otomeria plants
US9617331B2 (en) 2011-11-27 2017-04-11 Yeda Research And Development Co. Ltd. Methods of regulating angiogenesis by administering agents which increase apoB-100 polypeptide
ES2673471T3 (en) 2011-12-08 2018-06-22 Yeda Research And Development Co. Ltd. Mammalian fetal lung cells and therapeutic use thereof
WO2013093921A1 (en) 2011-12-20 2013-06-27 Collplant Ltd. Collagen coated synthetic polymer fibers
RU2657758C2 (en) 2011-12-22 2018-06-15 Иеда Рисеч Энд Девелопмент Ко. Лтд. Combination therapy for stable and long-term transplant engraftment
CN104254395B (en) 2011-12-22 2016-05-04 生命科技公司 For the sequential lateral flow capillary device of analyte determination
EP2797405A1 (en) 2011-12-28 2014-11-05 Kaiima Bio Agritech Ltd. Cultivated sorghum plant having a partially or fully multiplied genome and uses of same
CN104080480A (en) 2012-01-01 2014-10-01 奇比艾企业有限公司 Endo180-targeted particles for selective delivery of therapeutic and diagnostic agents
WO2013114363A2 (en) 2012-01-30 2013-08-08 Yeda Research And Development Co.Ltd. Antimicrobial agents
WO2013114374A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Dnase i polypeptides, polynucleotides encoding same, methods of producing dnase i and uses thereof in therapy
US10184131B2 (en) 2012-02-06 2019-01-22 A.B. Seeds Ltd. Isolated polynucleotides expressing or modulating microRNAs or targets of same, transgenic plants comprising same and uses thereof
BR112014020119A2 (en) 2012-02-13 2020-10-27 Gamida-Cell Ltd culture of mesenchymal stem cells
CN104427994A (en) 2012-02-14 2015-03-18 奥普科生物制品有限公司 Long-acting coagulation factors and methods of producing same
WO2013121405A1 (en) 2012-02-19 2013-08-22 Protalix Ltd. Oral unit dosage forms and uses of same for the treatment of gaucher disease
EP2844744A2 (en) 2012-02-22 2015-03-11 Brainstem Biotec Ltd. MicroRNAS FOR THE GENERATION OF ASTROCYTES
EP2844745A2 (en) 2012-02-22 2015-03-11 Brainstem Biotec Ltd. Generation of neural stem cells and motor neurons
WO2013128454A1 (en) 2012-03-01 2013-09-06 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization, (A.R.O.), Volcani Center Male sterile garlic plants, hybrid offspring of same and methods of generating and using same
EP3483184A1 (en) 2012-03-07 2019-05-15 Yeda Research and Development Co. Ltd Compositions for inhibition of quiescinsulfhydryl oxidase (qsox1) and uses of same
JP6445423B2 (en) 2012-03-20 2018-12-26 フマブス バイオメッド エスアー Antibody neutralizing RSV, MPV and PVM and use thereof
EP2828280B1 (en) 2012-03-22 2018-05-02 Ramot at Tel-Aviv University Ltd. Plif multimeric peptides and uses thereof
US12195550B2 (en) 2012-03-30 2025-01-14 The United States Of America As Represented By The Department Of Veterans Affairs Targeting intracellular target-binding determinants with intracellular antibodies
US9283272B2 (en) 2012-03-30 2016-03-15 The United States Of America As Represented By The Department Of Veterans Affairs Targeting intracellular target-binding determinants with intracellular antibodies
WO2013156989A1 (en) 2012-04-18 2013-10-24 Ramot At Tel-Aviv University Ltd. Lipidated glycosaminoglycan particles for the delivery of nucleic acids
BR112014025951A2 (en) 2012-04-19 2017-07-11 Opko Biologics Ltd long-acting oxyntomodulin variants and production methods
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
ES2806945T3 (en) 2012-04-26 2021-02-19 Univ Chicago Staphylococcal coagulase antigens and methods for their use
ES2627816T3 (en) 2012-05-09 2017-07-31 Yeda Research And Development Co. Ltd. Variants of the pro-domain of tace as a TNF-a inhibitor and its medical use
US8865158B2 (en) 2012-05-22 2014-10-21 Ramot At Tel-Aviv University Ltd. Bacteriophages for reducing toxicity of bacteria
EP2855521A4 (en) 2012-05-24 2016-03-02 Mountgate Group Ltd Compositions and methods related to prevention and treatment of rabies infection
WO2013175480A1 (en) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
EP2855507B1 (en) 2012-06-03 2018-01-03 Ben-Gurion University of The Negev Research and Development Authority Functionalized titanium binding peptides and implants coated with same
EP2854838B1 (en) 2012-06-04 2018-10-17 OPKO Biologics Ltd. Pegylated oxm variants
EP2870110A1 (en) 2012-07-03 2015-05-13 Nanospun Technologies Ltd. Methods and devices for adsorption and biodegradation of petroleum
US9175266B2 (en) 2012-07-23 2015-11-03 Gamida Cell Ltd. Enhancement of natural killer (NK) cell proliferation and activity
US9567569B2 (en) 2012-07-23 2017-02-14 Gamida Cell Ltd. Methods of culturing and expanding mesenchymal stem cells
DK2880155T3 (en) 2012-07-29 2019-07-15 Yeda Res & Dev USE OF THE REDUCING GLYCINE ROAD FOR GENERATING FORMATOTROPHIC AND AUTOTROPHIC MICRO-ORGANISMS
WO2014020608A1 (en) 2012-07-31 2014-02-06 Yeda Research And Development Co. Ltd. Methods of diagnosing and treating motor neuron diseases
CA2877223C (en) 2012-08-06 2019-08-27 Brainstorm Cell Therapeutics Ltd. Methods of generating mesenchymal stem cells which secrete neurotrophic factors
EP2698377A1 (en) 2012-08-17 2014-02-19 Laboratorios Del. Dr. Esteve, S.A. Enhanced rapid immunogen selection method for HIV gp120 variants
AR092868A1 (en) 2012-09-03 2015-05-06 A B Seeds Ltd METHOD FOR IMPROVING TOLERANCE TO THE ABIOTIC STRESS OF PLANTS AND PLANTS GENERATED THROUGH SUCH METHOD
EP2895197B1 (en) 2012-09-12 2020-02-26 Ramot at Tel-Aviv University Ltd. Immunoparticles and methods of generating and using same
BR112015006840A2 (en) 2012-09-27 2017-11-21 Res Found Dev attenuated chikungunya virus
US11105809B2 (en) 2012-10-09 2021-08-31 Ramot At Tel-Aviv University Ltd. Methods and kits for predicting prognosis of cancer using soluble mortalin in blood
EP2912062A1 (en) 2012-10-24 2015-09-02 Yeda Research and Development Co. Ltd. Combinations of epidermal growth factor receptor targeting antibodies for treating cancer
EP2912181B1 (en) 2012-10-29 2017-11-29 Yeda Research and Development Co., Ltd. Aptamers, multimeric aptamers and uses thereof
AU2013349239B2 (en) 2012-11-20 2018-04-12 Opko Biologics Ltd. Method of increasing the hydrodynamic volume of polypeptides by attaching to gonadotrophin carboxy terminal peptides
MX2015004626A (en) 2012-11-29 2015-07-14 Yeda Res & Dev Methods of preventing tumor metastasis, treating and prognosing cancer and identifying agents which are putative metastasis inhibitors.
WO2015079413A2 (en) 2013-11-28 2015-06-04 Yeda Research And Development Co. Ltd. Synaptojanin-2 inhibitors and uses thereof
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
EP2941488B1 (en) 2013-01-01 2023-03-22 Monsanto Technology LLC Methods of introducing dsrna to plant seeds for modulating gene expression
WO2014108850A2 (en) 2013-01-09 2014-07-17 Yeda Research And Development Co. Ltd. High throughput transcriptome analysis
WO2014108854A1 (en) 2013-01-09 2014-07-17 Fusimab Ltd. Monospecific anti-hgf and anti-ang2 antibodies and bispecific anti-hgf/anti-ang2 antibodies
CN104937412B (en) 2013-01-17 2018-05-25 诺威尔卢斯德克有限公司 For identifying the method and system of the specific driving mutation-ure of patient
EP2950808B1 (en) 2013-02-04 2019-08-21 Ramot at Tel-Aviv University Ltd. Generation of cytotoxic tumor specific cell lines and uses thereof
US20160017021A1 (en) 2013-03-06 2016-01-21 Protalix Ltd. TNF alpha INHIBITOR POLYPEPTIDES, POLYNUCLEOTIDES ENCODING SAME, CELLS EXPRESSING SAME AND METHODS OF PRODUCING SAME
CA2902727C (en) 2013-03-06 2020-08-18 Protalix Ltd. Use of plant cells expressing a tnfalpha polypeptide inhibitor in therapy
EP2964254B1 (en) 2013-03-07 2019-09-18 University of Maryland, Baltimore Immunotherapeutic potential of modified lipooligosaccharides/lipid a
EP3604535A3 (en) 2013-03-13 2020-04-22 Monsanto Technology LLC Methods and compositions for weed control
BR112015022797A2 (en) 2013-03-13 2017-11-07 Monsanto Technology Llc weed control method, herbicidal composition, microbial expression cassette and polynucleotide production method
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
WO2014147622A1 (en) 2013-03-21 2014-09-25 Collplant Ltd. Compositions comprising collagen and prp for tissue regeneration
EP2976109B1 (en) 2013-03-21 2018-07-25 Genisphere, LLC Cellular delivery of dna intercalating agents
MX363896B (en) 2013-03-24 2019-04-05 Biokine Therapeutics Ltd Methods of treating myeloid leukemia.
BR112015026702A2 (en) 2013-04-21 2018-02-06 Yeda Res And Developmente Co Ltd senescent cell killing methods
ES2831424T3 (en) 2013-04-23 2021-06-08 Yeda Res & Dev Isolated naive pluripotent stem cells and methods to generate them
CN105555796B (en) 2013-04-25 2019-09-17 耶达研究及发展有限公司 Use of inhibitory peptides for the treatment of inflammatory diseases
US20160115231A1 (en) 2013-05-21 2016-04-28 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Treatment of mast cell related pathologies
WO2014191995A2 (en) 2013-05-27 2014-12-04 Rakuto Bio Technologies Ltd. Enzymatic system-containing cosmetic compositions
WO2014207744A1 (en) 2013-06-24 2014-12-31 Ramot At Tel-Aviv University Ltd. Omentum based scaffold and delivery system
CN105980567B (en) 2013-07-19 2021-04-16 孟山都技术有限公司 Compositions and methods for controlling phyllometaca
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
WO2015015489A1 (en) 2013-07-30 2015-02-05 Biolinerx Ltd. Antibody for treating diabetes and autoimmune diseases
EP3039030B1 (en) 2013-08-29 2018-09-19 Yeda Research and Development Co. Ltd. Selective inhibitors of alpha2 isoform of na,k-atpase and use for reduction of intra-ocular pressure
WO2015033343A1 (en) 2013-09-03 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for expressing recombinant polypeptides
IL228284A (en) 2013-09-03 2016-12-29 Technion Res & Dev Foundation Implants composed of cellular scaffolds and a vascular pedicle
WO2015033344A1 (en) 2013-09-05 2015-03-12 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and kits for inhibiting pathogenicity of group a streptococcus (gas) or group g streptococcus (ggs)
WO2015037009A1 (en) 2013-09-16 2015-03-19 Plexicure Ltd. Isolated proteins capable of binding plexin-a4 and methods of producing and using same
EP3046929B1 (en) 2013-09-17 2019-01-16 Yeda Research and Development Co., Ltd. Erk-derived peptides and uses thereof
EP3052191B1 (en) 2013-10-01 2020-03-18 Kadimastem Ltd. Directed differentiation of astrocytes from human pluripotent stem cells for use in drug screening and the treatment of amyotrophic lateral sclerosis (als)
KR102357635B1 (en) 2013-10-02 2022-01-28 메디뮨 엘엘씨 Neutralizing anti-influenza a antibodies and uses thereof
US20150158926A1 (en) 2013-10-21 2015-06-11 Opko Biologics, Ltd. Long-acting polypeptides and methods of producing and administering same
AU2014338575B2 (en) 2013-10-21 2019-11-07 Opko Biologics Ltd. Long-acting polypeptides and methods of producing and administering same
US10767156B2 (en) 2013-10-24 2020-09-08 Yeda Research And Development Co., Ltd. Polynucleotides encoding BREX system polypeptides and methods of using same
WO2015063768A1 (en) 2013-10-31 2015-05-07 Biokine Therapeutics Ltd. Methods of treating acute myeloid leukemia with a flt3 mutation
NZ719544A (en) 2013-11-04 2022-09-30 Beeologics Inc Compositions and methods for controlling arthropod parasite and pest infestations
WO2015079411A1 (en) 2013-11-28 2015-06-04 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
ES2697757T3 (en) 2013-12-10 2019-01-28 Yeda Res & Dev Use of enzymes that catalyze the synthesis of pyruvate from formate and acetyl-CoA and bacteria that express the same
UA119253C2 (en) 2013-12-10 2019-05-27 Біолоджикс, Інк. Compositions and methods for virus control in varroa mite and bees
UA121462C2 (en) 2014-01-15 2020-06-10 Монсанто Текнолоджі Елелсі Methods and compositions for weed control using epsps polynucleotides
WO2015114633A1 (en) 2014-01-30 2015-08-06 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenes is and treating medical conditions associated with same
CN106470699A (en) 2014-02-03 2017-03-01 耶路撒冷希伯来大学的益生研究开发有限公司 Consume the purposes of stem cell using casein kinase i inhibitor
JP2017506228A (en) 2014-02-05 2017-03-02 イェダ リサーチ アンド ディベロップメント カンパニー リミテッドYeda Research And Development Co.Ltd. MicroRNA for the treatment and diagnosis of serotonin releasing hormone, adrenergic releasing hormone, noradrenaline releasing hormone, glutamate releasing hormone and corticotropin releasing hormone related medical conditions and compositions comprising said microRNA
CN106573976B (en) 2014-02-06 2020-05-05 耶达研究及发展有限公司 anti-CD 84 antibodies, compositions comprising the antibodies, and uses thereof
US20170101633A1 (en) 2014-02-10 2017-04-13 Protalix Ltd. Method of maintaining disease stability in a subject having gaucher's disease
JP6628253B2 (en) 2014-02-11 2020-01-08 ブレインストーム セル セラペウティクス リミテッド Method for determining cell suitability
CN106255882A (en) 2014-03-03 2016-12-21 耶路撒冷希伯来大学伊森姆研究发展公司 For the method and apparatus detecting Pseudomonas aeruginosa
EP2923709A1 (en) 2014-03-28 2015-09-30 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Multi-component-multistage malaria vaccine
EP3125676A4 (en) 2014-04-01 2018-02-14 Monsanto Technology LLC Compositions and methods for controlling insect pests
CA2945438C (en) 2014-04-10 2023-08-22 Bonus Therapeutics Ltd. Bone repair compositions
CN106574296B (en) 2014-04-14 2021-03-02 耶路撒冷希伯来大学伊森姆研究发展公司 Method and kit for determining tissue or cell origin of DNA
WO2015159295A1 (en) 2014-04-17 2015-10-22 Yeda Research And Development Co. Ltd. Methods and kits for analyzing dna binding moieties attached to dna
US11427647B2 (en) 2014-04-27 2022-08-30 Famewave Ltd. Polynucleotides encoding humanized antibodies against CEACAM1
JP6805428B2 (en) 2014-04-27 2021-01-06 フェイムウェイヴ リミテッド Humanized antibody against CEACAM1
CN106460048B (en) 2014-04-28 2021-01-05 耶达研究及发展有限公司 Microbiome response to agents
MX2016014128A (en) 2014-05-04 2017-05-23 Forrest Innovations Ltd COMPOSITIONS AND PROCEDURES TO RECOVER THE GREENING OF CITRUSES INDUCED BY PATHOGENS.
JP6836500B2 (en) 2014-05-16 2021-03-03 ベイラー リサーチ インスティテュートBaylor Research Institute Methods and compositions for treating autoimmune and inflammatory conditions
EP3145947B1 (en) 2014-05-22 2025-02-12 Yeda Research and Development Co., Ltd. Recombinant microorganisms capable of carbon fixation
EP3149155B1 (en) 2014-06-02 2020-09-23 Kadimastem Ltd. Methods of inducing myelination and maturation of oligodendrocytes
WO2015186129A1 (en) 2014-06-02 2015-12-10 Technion Research & Development Foundation Limited. Compositions and methods of selectively inhibiting irp1 and treating inflammation
WO2015200223A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
EP3145951A1 (en) 2014-06-24 2017-03-29 InSight Biopharmaceuticals Ltd. Methods of purifying antibodies
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
AU2015278659A1 (en) 2014-06-25 2017-02-02 Tel Hashomer Medical Research Infrastructure And Services Ltd. Identification of cancer stem cell markers and use of same for diagnosis and treatment
US10583084B2 (en) 2014-06-26 2020-03-10 Ramot At Tel-Aviv University Ltd. Liposomal formulations for delivery of nucleic acids
WO2016005985A2 (en) 2014-07-09 2016-01-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming cells
EP3169343B1 (en) 2014-07-15 2020-03-25 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Isolated polypeptides of cd44 and uses thereof
WO2016011035A2 (en) 2014-07-15 2016-01-21 Medlmmune, Llc Neutralizing anti-influenza b antibodies and uses thereof
CN106715719B (en) 2014-07-21 2022-08-02 福尔生物治疗有限公司 Method for determining drug response to patient specific mutations
CA2955414A1 (en) 2014-07-21 2016-01-28 Novellusdx Ltd. Methods and systems for determining oncogenic index of patient specific mutations
CN114009454A (en) 2014-07-29 2022-02-08 孟山都技术公司 Compositions and methods for controlling insect pests
WO2016016894A1 (en) 2014-07-30 2016-02-04 Yeda Research And Development Co. Ltd. Media for culturing pluripotent stem cells
CA2954601C (en) 2014-08-14 2023-04-18 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
WO2016030899A1 (en) 2014-08-28 2016-03-03 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral scleroses
EP2992895A1 (en) 2014-09-08 2016-03-09 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Three-component-multistage malaria vaccine
CA2959775A1 (en) 2014-09-08 2016-03-17 Yeda Research And Development Co. Ltd. Compositions and methods for treating cancer resistant to a tyrosine kinase inhibitor (tki)
CA2959716A1 (en) 2014-09-08 2016-03-17 Yeda Research And Development Co. Ltd. Anti-her3 antibodies and uses of same
IL234638A0 (en) 2014-09-14 2014-12-02 Yeda Res & Dev Nmda receptor antagonists for treating gaucher disease
EP3230453B1 (en) 2014-09-21 2020-05-20 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Downregulating mir-132 for the treatment of lipid related disorders
WO2016055950A1 (en) 2014-10-08 2016-04-14 Novartis Ag Combination of human cytomegalovirus neutralizing antibodies
DE102015220401B4 (en) 2014-10-20 2022-12-29 Gen-Probe Incorporated Erythrocyte Lysis Solution
US10570368B2 (en) 2014-11-13 2020-02-25 Enzootic Holdings Ltd. Functional sex-reversal of decapod crustacean females
WO2016075546A2 (en) 2014-11-14 2016-05-19 Antonio Lanzavecchia Antibodies that neutralize ebola virus and uses thereof
EP3220945A2 (en) 2014-11-17 2017-09-27 Yeda Research and Development Co., Ltd. Methods of treating diseases related to mitochondrial function
EP3221470B1 (en) 2014-11-17 2019-08-14 Yeda Research and Development Co., Ltd. Method of analyzing microbiome
EP3831404A1 (en) 2014-11-18 2021-06-09 Humabs Biomed S.A. Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof
WO2016079739A2 (en) 2014-11-20 2016-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions and methods for producing polypeptides with a modified glycosylation pattern in plant cells
CN107208070B (en) 2014-11-26 2021-09-07 技术创新动力基金(以色列)有限合伙公司 Targeted elimination of bacterial genes
CA2968808A1 (en) 2014-11-27 2016-06-02 Danziger Innovations Ltd. Nucleic acid constructs for genome editing
WO2016092555A2 (en) 2014-12-11 2016-06-16 Yeda Research And Development Co. Ltd. Isolated phosphotriesterase polypeptides, polynucleotides encoding same and uses thereof in treating or preventing organophosphate exposure associated damage
US20170269081A1 (en) 2014-12-11 2017-09-21 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
WO2016103269A1 (en) 2014-12-23 2016-06-30 Ramot At Tel-Aviv University Ltd. Populations of neural progenitor cells and methods of producing and using same
ES2880346T3 (en) 2014-12-30 2021-11-24 Cell Cure Neurosciences Ltd Evaluation of retinal pigment epithelial cell populations
SG11201705379VA (en) 2014-12-30 2017-08-30 Cell Cure Neurosciences Ltd Rpe cell populations and methods of generating same
SG11201705378RA (en) 2014-12-30 2017-08-30 Cell Cure Neurosciences Ltd Methods of treating retinal diseases
CN107406837A (en) 2015-01-04 2017-11-28 波塔力克斯有限公司 DNA enzymatic of modification and application thereof
WO2016116935A1 (en) 2015-01-21 2016-07-28 Yeda Research And Development Co. Ltd. Use of rasa2 as a prognostic and therapeutic marker for melanoma
PL3256589T3 (en) 2015-01-22 2022-02-21 Monsanto Technology Llc Compositions and methods for controlling leptinotarsa
WO2016135732A1 (en) 2015-02-26 2016-09-01 Yeda Research And Development Co. Ltd. Method of promoting hair growth
EP3268475B1 (en) 2015-03-11 2020-10-21 Yissum Research and Development Company of the Hebrew University of Jerusalem Ltd. Decoy oligonucleotides for the treatment of diseases
IL237852A0 (en) 2015-03-19 2016-03-24 Yeda Res & Dev Anti amphiregulin antibodies, compositions comprising same and uses thereof
CN107530427A (en) 2015-03-27 2018-01-02 南加利福尼亚大学 For the LHR of the treatment for entity tumor CAR T cell therapies
EP3273971A4 (en) 2015-03-27 2018-12-05 Yeda Research and Development Co. Ltd. Methods of treating motor neuron diseases
BR112017021016A2 (en) 2015-03-31 2018-07-03 Yeda Research And Development Co Ltd protein preparation, pharmaceutical composition, fusion protein, isolated polynucleotide, nucleic acid structure, method for treating glutamate-associated disease or condition, and method of purifying a polypeptide
US10960035B2 (en) 2015-04-01 2021-03-30 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Voleaui Center) Erodium crassifolium L'Her plant extracts and uses thereof
DK3280401T3 (en) 2015-04-07 2021-11-15 Ela Pharma Ltd COMPOSITIONS FOR THE TREATMENT AND / OR PREVENTION OF CELL OR TISSUE CROSS SPECIFICALLY DIRECTED AT KATHEPSIN C AND / OR CELA1 AND / OR CELA3A AND / OR STRUCTURELY RELATED
EP3081575A1 (en) 2015-04-12 2016-10-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Anti-plasmodium parasite antibodies
CA2986202C (en) 2015-04-27 2023-08-22 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Egr1 targeting molecules for the treatment of inflammatory and hyperproliferative conditions
BR112017023448A2 (en) 2015-04-29 2018-07-31 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) anti-phytopathogenic compositions
US20190031759A1 (en) 2015-04-30 2019-01-31 Technion Research & Development Foundation Limited Chimeric antigen receptors and methods of their use
CN108026566A (en) 2015-05-04 2018-05-11 特拉维夫大学拉莫特有限公司 For making the method and kit of DNA fragmentation
EP3294280A1 (en) 2015-05-11 2018-03-21 Yeda Research and Development Co., Ltd. Citrin inhibitors for the treatment of cancer
US11219636B2 (en) 2015-05-17 2022-01-11 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Compositions and methods for treating cancer
WO2016185457A1 (en) 2015-05-19 2016-11-24 Yeda Research And Development Co. Ltd. Methods of promoting lymphangiogenesis
WO2016185481A2 (en) 2015-05-20 2016-11-24 Yeda Research And Development Co. Ltd. Method of targeting senescent cells
MX2017014787A (en) 2015-05-21 2018-05-01 Yeda Res & Dev Bacterial populations for promoting health.
CA2987706A1 (en) 2015-05-29 2016-12-08 Opko Biologics Ltd. Pegylated oxyntomodulin variants
CN113480640B (en) 2015-06-01 2024-07-30 免疫医疗有限责任公司 Neutralizing anti-influenza binding molecules and uses thereof
CN107750125A (en) 2015-06-02 2018-03-02 孟山都技术有限公司 For by the composition and method in delivery of polynucleotides to plant
CN108024517A (en) 2015-06-03 2018-05-11 孟山都技术公司 For the method and composition introducing nucleic acid in plant
JP7010473B2 (en) 2015-06-04 2022-02-10 ユニバーシティ オブ サザン カリフォルニア LYM-1 and LYM-2 Targeted CAR Cell Immunotherapy
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
US10668109B2 (en) 2015-06-18 2020-06-02 Yeda Research And Development Co. Ltd. Conditioning protocols and use of same for tissue regeneration
WO2016203476A1 (en) 2015-06-18 2016-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Methods and compositions for diagnosing and treating urothelial cancer
US10960058B2 (en) 2015-06-19 2021-03-30 Opko Biologics Ltd. Long-acting coagulation factors and methods of producing same
WO2016207402A1 (en) 2015-06-26 2016-12-29 Institute For Research In Biomedicine Proteins comprising a mutated lair-1 fragment and uses thereof
EP3943098A3 (en) 2015-07-16 2022-05-11 Biokine Therapeutics Ltd. Compositions and methods for treating cancer
CN114457039A (en) 2015-07-16 2022-05-10 耶达研究及发展有限公司 Gene-modified anti-third-party central memory T cells and their use in immunotherapy
EP3907231A1 (en) 2015-07-19 2021-11-10 Yeda Research and Development Co., Ltd. Selective inhibitors of alpha2-containing isoforms of na,k-atpase and use thereof for reducing intraocular pressure
CA2993023C (en) 2015-07-22 2020-04-28 Phytopharma International Ltd. Bee-ingestible compositions, methods of using same for producing honey and honey produced thereby
EP3862425A1 (en) 2015-07-29 2021-08-11 Hadasit Medical Research Services and Development Ltd. Large scale production of retinal pigment epithelial cells
ES2965461T3 (en) 2015-08-03 2024-04-15 Biokine Therapeutics Ltd CXCR4 inhibitor for cancer treatment
WO2017021961A1 (en) 2015-08-04 2017-02-09 Yeda Research And Development Co. Ltd. Methods of screening for riboswitches and attenuators
DK3331994T3 (en) 2015-08-05 2022-11-21 Cell Cure Neurosciences Ltd PRODUCTION OF RETINAL PIGMENT EPITHELIAL CELLS
JP6868608B2 (en) 2015-08-05 2021-05-12 セル キュア ニューロサイエンシズ リミテッド Preparation of photoreceptors for the treatment of retinal diseases
EP3334449B1 (en) 2015-08-10 2021-09-29 The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center Methods and pharmaceutical compositions for improving wound healing using cd24
US20180237790A1 (en) 2015-08-13 2018-08-23 Forrest Innovation Ltd. Formulations and compositions for delivery of nucleic acids to plant cells
WO2017033188A1 (en) 2015-08-24 2017-03-02 Yeda Research And Development Co. Ltd. Algal oil and biofuel and methods of producing same
US10765706B2 (en) 2015-09-03 2020-09-08 University Of South Florida Method of stem cell delivery into the brain during chronic disease using blood brain barrier permeabilizers
WO2017042816A1 (en) 2015-09-10 2017-03-16 Yeda Research And Development Co. Ltd. Ablation of perforin positive dendritic cells in cancer treatment
WO2017059878A1 (en) 2015-10-07 2017-04-13 Humabs Biomed Sa Antibodies that potently neutralize hepatitis b virus and uses thereof
WO2017072757A1 (en) 2015-10-25 2017-05-04 Yeda Research And Development Co. Ltd. Antibodies targeting quiescin sulfhydryl oxidase (qsox1) and uses of same
JP6987769B2 (en) 2015-10-26 2022-01-05 セル キュア ニューロサイエンシズ リミテッド Preparation method of retinal pigment epithelial cells
BR112018008601A2 (en) 2015-10-27 2018-10-30 Jay Pharma Inc compositions comprising cannabidiol and second therapeutic agents for the treatment of cancer
IL242380A0 (en) 2015-10-29 2016-02-01 Yeda Res & Dev A method of inducing cardiomyocytes proliferation and treating heart diseases
EP3370791A1 (en) 2015-11-03 2018-09-12 Ariel-University Research and Development Company Ltd. Compositions for regeneration and repair of neural tissue
WO2017081689A1 (en) 2015-11-11 2017-05-18 Ramot At Tel-Aviv University Ltd. Methods of detecting 5-hydroxymethylcytosine and diagnosing of cancer
WO2017094001A1 (en) 2015-11-30 2017-06-08 Kadimastem Ltd Methods for differentiating and purifying pancreatic endocrine cells
EP3176183A1 (en) 2015-12-02 2017-06-07 Yeda Research and Development Co. Ltd Compositions and methods for treating cancer not resistant to a tyrosine kinase inhibitor (tki)
WO2017103930A1 (en) 2015-12-16 2017-06-22 Ramot At Tel-Aviv University Ltd. Particles comprising decellularized omentum
IL260331B2 (en) 2015-12-28 2024-10-01 B G Negev Technologies And Applications Ltd At Ben Gurion Univ Composition and method for treating amyotrophic lateral sclerosis
WO2017118985A1 (en) 2016-01-06 2017-07-13 Yeda Research And Development Co. Ltd. Compositions and methods for treating malignant, autoimmune and inflammatory diseases
EP3403091B1 (en) 2016-01-11 2021-12-22 Technion Research & Development Foundation Limited Methods of determining prognosis of sepsis and treating same
EP3402513A4 (en) 2016-01-13 2019-10-23 Medlmmune, LLC Method of treating influenza a
JP7019580B2 (en) 2016-01-21 2022-02-15 ザ ステイト オブ イスラエル ミニストリー オブ アグリカルチャー アンド ルーラル ディベロップメント アグリカルチュラル リサーチ オーガニゼイション (エー.アール.オー.) (ボルカニ センター) Parthenogenetic plants and their manufacturing methods
IL243839B (en) 2016-01-28 2018-01-31 Sp Nano Ltd Conductive yarn
IL243838A (en) 2016-01-28 2017-07-31 Sp Nano Ltd Composition comprising sp1 and carbon based nanoparticles and uses thereof
WO2017130205A1 (en) 2016-01-31 2017-08-03 Hadasit Medical Research Services And Development Ltd. Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
US11230578B2 (en) 2016-02-04 2022-01-25 Yeda Research And Development Co. Ltd. Peptides and use of same in the treatment of diseases, disorders or conditions associated with a mutant P53
WO2017138008A2 (en) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. Methods of modulating protein exocytosis and uses of same in therapy
WO2017138007A1 (en) 2016-02-14 2017-08-17 Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science Microbiome-based diagnosis, prediction and treatment of relapsing obesity
BR112018016757A2 (en) 2016-02-16 2020-05-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. non-protein phenylalanine analogs to inhibit cyanobacteria and plant growth.
WO2017145162A1 (en) 2016-02-23 2017-08-31 Chaya Brodie Generation of cancer stem cells and use thereof
NZ745564A (en) 2016-03-01 2024-12-20 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Antibodies specific to human poliovirus receptor (pvr)
EP3907292A1 (en) 2016-03-03 2021-11-10 Memed Diagnostics Ltd. Analyzing rna for diagnosing infection type
US20190216891A1 (en) 2016-03-06 2019-07-18 Yeda Research And Development Co., Ltd. Method for modulating myelination
IL244649A0 (en) 2016-03-17 2016-06-30 Yeda Res & Dev Methods of isolating barrel-like proteases and identifying peptides processed thereby
US10421785B2 (en) 2016-04-11 2019-09-24 Bar-Ilan University Delta receptor agonist peptides and use thereof
EP3736332B1 (en) 2016-04-27 2025-02-12 Gen-Probe Incorporated Blood cell lysis reagent
EP3463402B1 (en) 2016-05-22 2021-06-23 Yeda Research and Development Co. Ltd. Methods of using pulmonary cells for transplantation and induction of tolerance
IL245861A0 (en) 2016-05-25 2016-09-04 Yeda Res & Dev Use of agents for treating drug resistant tumors
US20190100732A1 (en) 2016-06-02 2019-04-04 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Assay for the removal of methyl-cytosine residues from dna
EP3464322B1 (en) 2016-06-05 2023-04-05 Tel HaShomer Medical Research Infrastructure and Services Ltd. Novel molecules for the treatment of inflammation
EP3468610A1 (en) 2016-06-09 2019-04-17 OPKO Biologics Ltd. Long-acting oxyntomodulin formulation and methods of producing and administering same
US11859232B2 (en) 2016-06-19 2024-01-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Screening for chemotherapy resistance in human haploid cells
WO2018002924A1 (en) 2016-06-27 2018-01-04 Yeda Research And Development Co. Ltd. Veto cells generated from memory t cells
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
WO2018011804A1 (en) 2016-07-11 2018-01-18 Bonus Therapeutics Ltd. Cell compositions for tissue regeneration
IL246722A0 (en) 2016-07-11 2016-09-29 Yeda Res & Dev Combination therapy to increase endogenous nitric oxide (no) synthesis
IL302693A (en) 2016-07-11 2023-07-01 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Methods and systems for growing cells in culture
EP3481855B1 (en) 2016-07-11 2023-09-06 OPKO Biologics Ltd. Long-acting coagulation factor vii and methods of producing same
WO2018010789A1 (en) 2016-07-13 2018-01-18 Humabs Biomed Sa Novel antibodies specifically binding to zika virus epitopes and uses thereof
WO2018015881A1 (en) 2016-07-18 2018-01-25 Ramot At Tel-Aviv University Ltd. Modular platform for targeted therapeutics
WO2018020489A1 (en) 2016-07-24 2018-02-01 Yeda Research And Development Co. Ltd. Methods and kits for analyzing dna binding moieties attached to dna
EP3497231B1 (en) 2016-08-08 2023-10-04 Technology Innovation Momentum Fund (Israel) Limited Partnership Bacterial systems for analyzing ubiquitylated polypeptides
WO2018029690A1 (en) 2016-08-10 2018-02-15 Memed Diagnostics Ltd. System and method for analysis of biological data
WO2018029693A1 (en) 2016-08-10 2018-02-15 Ramot At Tel-Aviv University Ltd. Analysis of methylation status and copy number
ES2925527T3 (en) 2016-08-14 2022-10-18 Univ Ramot Exosomes derived from mesenchymal cells to treat neurological disorders
IL247368A0 (en) 2016-08-18 2016-11-30 Yeda Res & Dev Diagnostic and therapeutic uses of exosomes
WO2018037416A1 (en) 2016-08-25 2018-03-01 Yeda Research And Development Co. Ltd. Methods and compositions for treating autoimmune diseases
JP2020501506A (en) 2016-09-07 2020-01-23 イッサム リサーチ デベロップメント カンパニー オブ ザ ヘブリュー ユニバーシティー オブ エルサレム エルティーディー. Anti-NKp46 antibody and therapeutic use thereof
WO2018051347A1 (en) 2016-09-14 2018-03-22 Yeda Research And Development Co. Ltd. Crisp-seq, an integrated method for massively parallel single cell rna-seq and crispr pooled screens
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
IL248468A0 (en) 2016-10-13 2017-01-31 Technion Res & Dev Foundation Use of caspase-3 inhibitors and caspase-3 activators in the manufacture of medicament for treating cancer and wound healing
IL248385A0 (en) 2016-10-18 2017-02-01 Yeda Res & Dev Treatment of a circadian rhythm disorder
US10662226B2 (en) 2016-10-28 2020-05-26 The Regents of the University of Caiifomia Synthetic beta-amyloid peptides capable of forming stable antigenic oligomers
US20190359956A1 (en) 2016-11-10 2019-11-28 Yeda Research And Development Co. Ltd. Phosphotriesterases for treating or preventing organophosphate exposure associated damage
EP3545095A1 (en) 2016-11-28 2019-10-02 Yeda Research and Development Co., Ltd. Isolated polynucleotides and polypeptides and methods of using same for expressing an expression product of interest
EP3548015A1 (en) 2016-11-30 2019-10-09 Yeda Research and Development Co. Ltd. Methods of treating liver toxicity and disorders
WO2018100511A1 (en) 2016-12-01 2018-06-07 Ramot At Tel-Aviv University Ltd. Combined treatment for nerve injuries
CN110392736A (en) 2017-01-18 2019-10-29 耶达研究及发展有限公司 Genetically modified counter-suppressor cells and their use in immunotherapy
WO2018138668A1 (en) 2017-01-25 2018-08-02 Mor Research Applications Ltd. Methods of diagnosing malignant diseases
IL250479A0 (en) 2017-02-06 2017-03-30 Sorek Rotem Isolated cells genetically modified to express a disarm system having an anti-phage activity and methods of producing same
IL250916A0 (en) 2017-03-02 2017-06-29 Geiger Benjamin Methods of culturing t cells and uses of same
WO2018167780A1 (en) 2017-03-12 2018-09-20 Yeda Research And Development Co. Ltd. Methods of prognosing and treating cancer
EP3596469A1 (en) 2017-03-12 2020-01-22 Yeda Research and Development Co., Ltd. Methods of diagnosing and prognosing cancer
CN110913874A (en) 2017-03-16 2020-03-24 谱系细胞疗法公司 Method for measuring the efficacy of a retinal disease therapy
BR112019020953A2 (en) 2017-04-05 2020-05-05 Yeda Res & Dev ex vivo culture system and methods of using it
BR112019021824A2 (en) 2017-04-19 2020-06-02 Institute For Research In Biomedicine VACCINES AGAINST MALARIA AND PLASMODE SPOROZOYTE BINDING ANTIBODIES
IL252151A0 (en) 2017-05-07 2017-07-31 Fainzilber Michael Methods of treating psychiatric stress disorders
EP3621991A2 (en) 2017-05-10 2020-03-18 Ariel Scientific Innovations Ltd. Methods of purifying antibodies
US11714089B2 (en) 2017-05-21 2023-08-01 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Combination of markers for diagnosing cancer
WO2018216011A1 (en) 2017-05-23 2018-11-29 Technion Research & Development Foundation Limited Agents which inhibit gads dimerization and methods of use thereof
GB201708665D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing extractability of solids from coffee beans
GB201708662D0 (en) 2017-05-31 2017-07-12 Tropic Biosciences Uk Ltd Compositions and methods for increasing shelf-life of banana
US20200109408A1 (en) 2017-05-31 2020-04-09 Tropic Biosciences UK Limited Methods of selecting cells comprising genome editing events
WO2018229764A1 (en) 2017-06-13 2018-12-20 Yeda Research And Development Co. Ltd. Treatment of advanced or progressive multiple sclerosis
US20200340057A1 (en) 2017-07-13 2020-10-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Dna targets as tissue-specific methylation markers
US11466323B2 (en) 2017-07-13 2022-10-11 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Dual-probe digital droplet PCR strategy for specific detection of tissue-specific circulating DNA molecules
WO2019012542A1 (en) 2017-07-13 2019-01-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Detecting tissue-specific dna
IL253642A0 (en) 2017-07-24 2017-09-28 Seger Rony Combination therapy for the treatment of cancer
IL253984A0 (en) 2017-08-14 2017-09-28 Yeda Res & Dev Immunotherapy against transferrin receptor 1 (tfr1)-tropic arenaviruses
US11692166B2 (en) 2017-08-23 2023-07-04 Technion Research & Development Foundation Limited Compositions and methods for improving alcohol tolerance in yeast
WO2019042555A1 (en) 2017-08-31 2019-03-07 Humabs Biomed Sa Multispecific antibodies specifically binding to zika virus epitopes and uses thereof
CA3074948A1 (en) 2017-09-19 2019-03-28 Tropic Biosciences UK Limited Modifying the specificity of plant non-coding rna molecules for silencing gene expression
US11701391B2 (en) 2017-10-24 2023-07-18 Dalia ELANI Methods of treating an ischemic disease
US11591385B2 (en) 2017-11-09 2023-02-28 Pinteon Therapeutics Inc. Methods and compositions for the generation and use of humanized conformation-specific phosphorylated tau antibodies
IL255664A0 (en) 2017-11-14 2017-12-31 Shachar Idit Hematopoietic stem cells with improved properties
CN111615332A (en) 2017-11-29 2020-09-01 维德奥特有限公司 Compositions, kits and methods for controlling amaranth weeds
IL274979B2 (en) 2017-11-29 2024-07-01 Univ Ramot Methods of preventing or treating neurogenic shock
EP3716993A1 (en) 2017-12-03 2020-10-07 Yeda Research and Development Co. Ltd Treatment of an ischemic heart disease
EP3723785A1 (en) 2017-12-17 2020-10-21 Yeda Research and Development Co. Ltd Cop9 signalosome (csn) complex modulators and uses thereof
EP3731965A1 (en) 2017-12-28 2020-11-04 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method to reproduce circadian rhythms on a microfluidic chip
IL257225A (en) 2018-01-29 2018-04-09 Yeda Res & Dev Treatment of sarcoma
IL257269A (en) 2018-01-31 2018-04-09 Olender Tsviya Endoplasmic reticulum targeting signal
EP3749689A1 (en) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Inhibitors of the 20s proteasome
EP3749368A1 (en) 2018-02-08 2020-12-16 Yeda Research and Development Co. Ltd Methods of identifying and using agents for treating diseases associated with intestinal barrier dysfunction
US11571433B2 (en) 2018-02-23 2023-02-07 Carmel Haifa University Economic Corporation Ltd. Methods for treating memory impairment and cognitive dysfunction
WO2019167047A1 (en) 2018-02-28 2019-09-06 The Medical Research, Infrastructure and Health Services Fund of the Tel Aviv Medical Center Methods of diagnosing and treating bladder cancer
WO2019175869A1 (en) 2018-03-12 2019-09-19 Yeda Research And Development Co. Ltd Treatment of a heart disease
WO2019183500A1 (en) 2018-03-23 2019-09-26 Hung Chiung Yu Coccidioides antigens and methods of their use
EP3774047A1 (en) 2018-03-29 2021-02-17 Yeda Research and Development Co. Ltd Use of electric field gradients to control gene expression
EP3773506A4 (en) 2018-03-29 2021-12-22 Technion Research & Development Foundation Limited BUBBLES WITH A PTEN INHIBITOR AND USES
IL258467A (en) 2018-03-29 2018-07-04 Ilana Kolodkin Gal Methods of disrupting a biofilm and/or preventing formation of same
GB201807192D0 (en) 2018-05-01 2018-06-13 Tropic Biosciences Uk Ltd Compositions and methods for reducing caffeine content in coffee beans
WO2019220441A1 (en) 2018-05-15 2019-11-21 Hadasit Medical Research Services And Development Ltd. Compositions and methods for treating cancer resistant to an anti-cancer agent
IL259392A (en) 2018-05-15 2018-08-01 Yeda Res & Dev Vaccination with cancer neo-antigens
WO2019229745A1 (en) 2018-05-27 2019-12-05 Biolinerx Ltd. Agi-134 combined with a checkpoint inhibitor for the treatment of solid tumors
WO2019234754A1 (en) 2018-06-07 2019-12-12 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Nucleic acid constructs and methods of using same
US20210337753A1 (en) 2018-06-07 2021-11-04 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization Methods of regenerating and transforming cannabis
US11873322B2 (en) 2018-06-25 2024-01-16 Yeda Research And Development Co. Ltd. Systems and methods for increasing efficiency of genome editing
US20210292381A1 (en) 2018-07-04 2021-09-23 Ukko Inc. Methods of de-epitoping wheat proteins and use of same for the treatment of celiac disease
US20210269860A1 (en) 2018-07-08 2021-09-02 Yeda Research And Development Co. Ltd. Person-specific assessment of probiotics responsiveness
AU2019300567B2 (en) 2018-07-11 2024-09-19 Immunity Pharma Ltd. Peptide compounds and therapeutic uses of same
CA3104780A1 (en) 2018-07-11 2020-01-16 Kahr Medical Ltd. Sirpalpha-4-1bbl variant fusion protein and methods of use thereof
KR20210042430A (en) 2018-07-31 2021-04-19 콜플랜트 리미티드 Tobacco transformation event and detection method and use thereof
IL261156A (en) 2018-08-14 2020-02-27 Fass Deborah Chimeric quiescin sulfhydryl oxidase (qsox1) antibodies and uses of same
US11548938B2 (en) 2018-08-21 2023-01-10 Quidel Corporation DbpA antibodies and uses thereof
CA3108434A1 (en) 2018-08-24 2020-02-27 Yeda Research And Development Co. Ltd. Methods of modulating m2 macrophage polarization and use of same in therapy
WO2020058979A2 (en) 2018-09-20 2020-03-26 Yeda Research And Development Co. Ltd. Methods of treating amyotrophic lateral sclerosis
US20210338767A1 (en) 2018-09-25 2021-11-04 Biolinerx Ltd. Methods of selecting treatment for cxcr4-associated cancer
IL262658A (en) 2018-10-28 2020-04-30 Memorial Sloan Kettering Cancer Center Prevention of age related clonal hematopoiesis and diseases associated therewith
IL263184A (en) 2018-11-21 2020-05-31 Yarden Yosef Method of treating cancer and compositions for same
ES2961791T3 (en) 2018-12-19 2024-03-13 Humabs Biomed Sa Antibodies that neutralize the hepatitis B virus and their uses
EP3914698B1 (en) 2019-01-23 2024-12-11 Yeda Research and Development Co. Ltd Culture media for pluripotent stem cells
IL264768A (en) 2019-02-10 2020-08-31 Sagi Irit Anti-matrix metalloproteinase 7 (mmp-7) inhibitory antibody and uses thereof
IL264854A (en) 2019-02-14 2020-08-31 Bahat Anat Spt5 inhibitors and methods of use thereof
EP3927378A1 (en) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Method for reduction drug-induced nephrotoxicity
EP3927807A1 (en) 2019-02-21 2021-12-29 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Methods of generating organoids for high throughput screening of drugs
AU2020232441A1 (en) 2019-03-05 2021-09-23 The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) Genome-edited birds
EP3938400A4 (en) 2019-03-11 2022-11-23 Memorial Sloan Kettering Cancer Center CD22 ANTIBODIES AND METHODS OF USE THEREOF
GB201903519D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest
GB201903521D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd No title
GB201903520D0 (en) 2019-03-14 2019-05-01 Tropic Biosciences Uk Ltd Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells
IL265486A (en) 2019-03-19 2020-09-30 Yeda Res & Dev Bistable type ii opsins and uses thereof
WO2020193718A1 (en) 2019-03-27 2020-10-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Recombinant proteins with cd40 activating properties
WO2020194317A1 (en) 2019-03-28 2020-10-01 Yeda Research And Development Co. Ltd. Method of treating lipid-related disorders
US20220175807A1 (en) 2019-03-31 2022-06-09 Yeda Research And Development Co. Ltd. Anti-viral and anti-tumoral compounds
IL266433B (en) 2019-05-02 2020-11-30 Sagi Irit Compositions comprising the propeptide of lysyl oxidase and uses thereof
EP3969619A1 (en) 2019-05-13 2022-03-23 Yeda Research and Development Co. Ltd Cell-free mirna biomarkers for prognosis and diagnosis of neurodegenerative diseases
IL266728B (en) 2019-05-19 2020-11-30 Yeda Res & Dev Identification of recurrent mutated neopeptides
AU2020279080A1 (en) 2019-05-22 2022-01-20 Hadasit Medical Research Services And Development Ltd. Methods of culturing human pluripotent cells
WO2020237491A1 (en) 2019-05-28 2020-12-03 Shanghaitech University Composition and methods to treat ectodermal dysplasia 2, clouston type
US20220233477A1 (en) 2019-06-12 2022-07-28 Hadasit Medical Research Services And Development Ltd. Methods of generating oligodendrocytes
EP3983540A1 (en) 2019-06-16 2022-04-20 Yeda Research and Development Co. Ltd Method for stabilizing intracellular rna
WO2020261281A1 (en) 2019-06-27 2020-12-30 Ramot At Tel-Aviv University Ltd. Semaphorin 3a antibodies and uses thereof
EP3994268A1 (en) 2019-07-04 2022-05-11 Ukko Inc. De-epitoped alpha gliadin and use of same for the management of celiac disease and gluten sensitivity
MX2022000367A (en) 2019-07-11 2022-07-13 Kahr Medical Ltd HETERODIMERS, METHODS AND USE THEREOF.
IL268111A (en) 2019-07-16 2021-01-31 Fainzilber Michael Methods of treating pain
WO2021009740A1 (en) 2019-07-16 2021-01-21 Ramot At Tel-Aviv University Ltd. Compositions and methods for the treatment of tuberculosis
WO2021019526A1 (en) 2019-07-29 2021-02-04 Yeda Research And Development Co. Ltd. Methods of treating and diagnosing lung cancer
EP4004212A1 (en) 2019-07-30 2022-06-01 The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization (ARO) (Volcani Institute) Methods of controlling cannabinoid synthesis in plants or cells and plants and cells produced thereby
WO2021028909A1 (en) 2019-08-12 2021-02-18 Yeda Research And Development Co. Ltd. Dna repair blood test for predicting response of lung cancer patients to immunotherapy
WO2021033176A1 (en) 2019-08-22 2021-02-25 Ariel Scientific Innovations Ltd. Scaled-up methods for purifying antibodies
EP4021463A1 (en) 2019-08-27 2022-07-06 Yeda Research and Development Co. Ltd Treatment of bacterial vaginosis
CN114630680B (en) 2019-08-29 2024-10-11 维尔生物科技有限公司 Antibody compositions and methods for treating hepatitis B virus infection
WO2021048852A1 (en) 2019-09-11 2021-03-18 Yeda Research And Development Co. Ltd. Methods of treating breast cancer
IL269674B (en) 2019-09-25 2020-08-31 Roy Bar Ziv Assembly of protein complexes on a chip
IL270306A (en) 2019-10-30 2021-05-31 Yeda Res & Dev Prevention and treatment of pre-myeloid and myeloid malignancies
EP4051695A1 (en) 2019-10-31 2022-09-07 Yeda Research and Development Co., Ltd. Engineered autotrophic bacteria for co2 conversion to organic materials
EP4058477A2 (en) 2019-11-11 2022-09-21 IBI-AG Innovative Bio Insecticides Ltd. Insect control nanobodies and uses thereof
US20230022576A1 (en) 2019-11-19 2023-01-26 Protalix Ltd. Removal of constructs from transformed cells
IL270800A (en) 2019-11-20 2021-05-31 Yeda Res & Dev Method of treating alzheimer’s disease
EP4061835A1 (en) 2019-11-21 2022-09-28 Institut National de la Santé et de la Recherche Médicale (INSERM) Novel immunotherapies targeting pd-1 with anti-pd-1/il-15 immunocytokines
CN112898414B (en) 2019-12-04 2024-05-10 珠海泰诺麦博制药股份有限公司 Anti-human cytomegalovirus antibodies and uses thereof
EP4077731A1 (en) 2019-12-22 2022-10-26 Yeda Research and Development Co. Ltd Diagnosis of frontotemporal dementia
IL271656A (en) 2019-12-22 2021-06-30 Yeda Res & Dev Systems and methods for identifying cells that have undergone genome editing
WO2021137230A1 (en) 2019-12-31 2021-07-08 Kahr Medical Ltd. Methods of culturing t cells and uses of same
IL271778A (en) 2019-12-31 2021-06-30 Ichilov Tech Ltd Methods of treating atopic dermatitis
US20230048719A1 (en) 2019-12-31 2023-02-16 Kahr Medical Ltd. Methods of culturing t cells with a 4-1bbl fusion polypeptide and uses of same
IL272074B2 (en) 2020-01-15 2024-12-01 Immunity Pharma Ltd Peptide compounds and their use in methods of treating diseases
IL272194A (en) 2020-01-22 2021-07-29 Yeda Res & Dev Multispecific antibodies for use in treating diseases
WO2021152584A1 (en) 2020-01-28 2021-08-05 Ariel Scientific Innovations Ltd. Methods of analyzing cell membranes
EP4484956A2 (en) 2020-01-29 2025-01-01 MeMed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
WO2021152586A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Methods of analyzing microbiome, immunoglobulin profile and physiological state
IL272390A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Methods of treating cancer
IL272389A (en) 2020-01-30 2021-08-31 Yeda Res & Dev Articles of manufacture comprising anti pd-l1 antibodies and their use in therapy
WO2021152587A1 (en) 2020-01-30 2021-08-05 Yeda Research And Development Co. Ltd. Treating acute liver disease with tlr-mik inhibitors
KR20220151168A (en) 2020-02-09 2022-11-14 엔엘씨 파르마 엘티디 Rapid detection test for SARS-COV-2
IL272586A (en) 2020-02-10 2021-08-31 Yeda Res & Dev Method for analyzing cell clusters
WO2021173674A1 (en) 2020-02-26 2021-09-02 A2 Biotherapeutics, Inc. Polypeptides targeting mage-a3 peptide-mhc complexes and methods of use thereof
WO2021178637A1 (en) 2020-03-05 2021-09-10 Iowa State University Research Foundation, Inc. IMMUNOGENIC AND VACCINE COMPOSITIONS AGAINST SARS-CoV-2
EP4121441A1 (en) 2020-03-16 2023-01-25 Yeda Research and Development Co. Ltd Peptide analogs and use of same in treating diseases, disorders or conditions associated with a mutant p53 protein
IL296696A (en) 2020-03-29 2022-11-01 Yeda res & development co ltd Variants of beta-glucocerebrosidase for use in treating gaucher disease
CA3175870A1 (en) 2020-03-31 2021-10-07 Biomuse Ltd. Bacteria for the prevention and treatment of smoke-induced lung damage
WO2021205444A1 (en) 2020-04-06 2021-10-14 Yeda Research And Development Co. Ltd. Methods of diagnosing cancer and predicting responsiveness to therapy
WO2021205459A1 (en) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Cannabidiol-containing compositions and uses thereof
EP4135746A1 (en) 2020-04-13 2023-02-22 Exoprother Medical Ltd. Cell-derived vesicles comprising wild-type p53 protein for antiviral therapy
US20210322483A1 (en) 2020-04-16 2021-10-21 Ichilov Tech Ltd. Cell-derived particles presenting heterologous cd24 and use thereof in therapy
WO2021229577A1 (en) 2020-05-12 2021-11-18 Collplant Ltd. Collagen as a delivery tool for metal-based anti-viral agents
WO2021228836A1 (en) 2020-05-13 2021-11-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Recombinant proteins with ox40 activating properties
IL274811B (en) 2020-05-20 2021-05-31 Yeda Res & Dev Indexing spatial information for a single-cell downstream applications
CN116194575A (en) 2020-06-22 2023-05-30 拉莫特特拉维夫大学有限公司 Multi-subunit protein assemblies, cells expressing multi-subunit protein assemblies and uses thereof
WO2021262840A1 (en) 2020-06-24 2021-12-30 Vir Biotechnology, Inc. Engineered hepatitis b virus neutralizing antibodies and uses thereof
US20230293530A1 (en) 2020-06-24 2023-09-21 Yeda Research And Development Co. Ltd. Agents for sensitizing solid tumors to treatment
IL276599A (en) 2020-08-09 2022-03-01 Yeda Res & Dev Mage-a1 specific t cell receptor and uses thereof
IL276627A (en) 2020-08-10 2022-03-01 Yeda Res & Dev Compositions for diagnosis and treatment of coronavirus infections
WO2022038536A1 (en) 2020-08-18 2022-02-24 International Rice Research Institute Methods of increasing outcrossing rates in gramineae
IL277488A (en) 2020-09-21 2022-04-01 Yeda Res & Dev Method for modulating weight
EP4217370A2 (en) 2020-09-23 2023-08-02 Yeda Research and Development Co. Ltd Methods and compositions for treating coronaviral infections
IL277743A (en) 2020-10-01 2022-04-01 Yeda Res & Dev Method of diagnosing breast cancer
WO2022074646A1 (en) 2020-10-05 2022-04-14 Protalix Ltd. Dicer-like knock-out plant cells
WO2022074656A1 (en) 2020-10-07 2022-04-14 Protalix Ltd. Long-acting dnase
WO2022079719A1 (en) 2020-10-15 2022-04-21 Yeda Research And Development Co. Ltd. Method of treating myeloid malignancies
IL278401A (en) 2020-10-29 2022-05-01 Yeda Res & Dev Polynucleotides for rna editing and methods of using same
AU2021374966A1 (en) 2020-11-09 2023-06-15 1E Therapeutics, Ltd. Catalytic sequence based methods of treating or preventing bacterial infections
IL302707A (en) 2020-11-26 2023-07-01 Ukko Inc A subunit of glutenin that has been modified and has a high molecular weight and its uses
IL279559A (en) 2020-12-17 2022-07-01 Yeda Res & Dev Controlling the ubiquitination process of mlkl for disease treatment
WO2022144883A2 (en) 2020-12-28 2022-07-07 1E Therapeutics, Ltd. P21 mrna targeting dnazymes
KR20230126725A (en) 2020-12-28 2023-08-30 1이 테라퓨틱스 엘티디. P21 mRNA target site for silencing
EP4274886A2 (en) 2021-01-10 2023-11-15 Supermeat the Essence of Meat Ltd. Pluripotent stem cell aggregates and microtissues obtained therefrom for the cultured meat industry
US20240083843A1 (en) 2021-01-14 2024-03-14 Yeda Research And Development Co. Ltd. Methods of producing vitamin d
IL280340B (en) 2021-01-21 2022-04-01 Yeda Res & Dev Antibodies, peptides and combinations of same for the treatment or prevention of coronavirus infection
TW202245838A (en) 2021-01-26 2022-12-01 美商維爾生物科技股份有限公司 Compositions and methods for treating hepatitis b virus infection
JP2024506954A (en) 2021-02-18 2024-02-15 イェダ リサーチ アンド デベロップメント カンパニー リミテッド Genetically modified bacteria for vaccine production
EP4294428A1 (en) 2021-02-18 2023-12-27 Yeda Research and Development Co. Ltd Method of generating vaccines
CA3172265A1 (en) 2021-03-10 2022-09-15 Dimitri BIELI Antibodies against tdp-43 and methods of using the same
IL281561A (en) 2021-03-16 2022-10-01 Yeda Res & Dev Methods and devices for growing mouse embryos outside the uterus
EP4313091A1 (en) 2021-03-30 2024-02-07 Biomx Ltd. Pseudomonas bacteriophage and uses thereof
IL282188A (en) 2021-04-08 2022-11-01 Yeda Res & Dev A combined use of ketamine and retigabine (ezogabine) for the treatment of psychiatric disorders
AU2022272135A1 (en) 2021-05-12 2024-01-04 Biomx Ltd. Staphylococcus bacteriophage and uses thereof
IL283563A (en) 2021-05-30 2022-12-01 Yeda Res & Dev Anti-microbial peptide (amp) signatures for diagnostics, stratification, and treatment of microbiome-associated disease
EP4352509A1 (en) 2021-06-06 2024-04-17 Yeda Research and Development Co. Ltd Combined treatment for cancer
CA3230677A1 (en) 2021-06-13 2022-12-22 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Method for reprogramming human cells
EP4355502A1 (en) 2021-06-16 2024-04-24 Seedx Technologies Inc. Methods of sorting matthiola seeds
NL2028466B1 (en) 2021-06-16 2022-12-21 Sakata Holland B V Methods of sorting matthiola seeds
EP4362662A1 (en) 2021-07-02 2024-05-08 Tropic Biosciences UK Limited Delay or prevention of browning in banana fruit
KR20240046506A (en) 2021-07-18 2024-04-09 가미다-셀 리미티드 Therapeutic NK cell population
WO2023002492A1 (en) 2021-07-22 2023-01-26 Yeda Research And Development Co. Ltd. Codon optimization of nucleic acids
WO2023012584A2 (en) 2021-08-03 2023-02-09 Genicity Limited Engineered tcr complex and methods of using same
EP4130028A1 (en) 2021-08-03 2023-02-08 Rhazes Therapeutics Ltd Engineered tcr complex and methods of using same
AU2022325816A1 (en) 2021-08-10 2024-03-21 Gamida-Cell Ltd. Engineered nk cells, methods of their production and uses thereof
GB202112866D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to fusarium wilt in a banana
GB202112865D0 (en) 2021-09-09 2021-10-27 Tropic Biosciences Uk Ltd Resistance to black sigatoka disease in banana
IL286430A (en) 2021-09-14 2023-04-01 Yeda Res & Dev Multispecific antibodies for use in treating diseases
JP2024542847A (en) 2021-12-08 2024-11-15 イェダ リサーチ アンド デベロップメント カンパニー リミテッド Multipotent lung progenitor cells for lung regeneration
EP4469079A1 (en) 2022-01-28 2024-12-04 Pfizer Inc. Coronavirus antigen variants
EP4499108A1 (en) 2022-04-25 2025-02-05 Yeda Research and Development Co. Ltd Compositions for altering cyclic adp-ribose secondary messenger signalling
WO2023242155A1 (en) 2022-06-14 2023-12-21 Janssen Vaccines & Prevention B.V. Compositions and methods for the diagnosis of hiv infection
WO2025017036A1 (en) 2023-07-17 2025-01-23 Institut National de la Santé et de la Recherche Médicale Alphavirus nsp3 helical tubular scaffolds
WO2025027492A1 (en) 2023-07-31 2025-02-06 Pfizer Inc. Coronavirus antigen variants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE341239B (en) * 1967-09-06 1971-12-20 Pharmacia Ab
US3654090A (en) * 1968-09-24 1972-04-04 Organon Method for the determination of antigens and antibodies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE31006E (en) * 1968-09-24 1982-08-03 Akzona Incorporated Process for the demonstration and determination of reaction components having specific binding affinity for each other

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