CA3134234A1 - Methodes et systemes pour la detection d'androgenes 11-oxo par cl-sm/sm - Google Patents
Methodes et systemes pour la detection d'androgenes 11-oxo par cl-sm/sm Download PDFInfo
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- CA3134234A1 CA3134234A1 CA3134234A CA3134234A CA3134234A1 CA 3134234 A1 CA3134234 A1 CA 3134234A1 CA 3134234 A CA3134234 A CA 3134234A CA 3134234 A CA3134234 A CA 3134234A CA 3134234 A1 CA3134234 A1 CA 3134234A1
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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- G01N30/02—Column chromatography
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
L'invention concerne des méthodes, des systèmes et des produits programmes d'ordinateur pour utiliser une chromatographie liquide couplée à une spectrométrie de masse en tandem (CL-SM/SM) pour l'analyse de biomarqueurs endogènes, tels que des androgènes 11-oxo, dans un échantillon. Les androgènes 11-oxo peuvent comprendre au moins une molécule parmi la 11-hydroxyandrostènedione (11OHA), la 11-hydroxytestostérone (11OHT) ou la 11-cétotestostérone (11KT). Plus particulièrement, l'invention concerne des méthodes, des systèmes et des produits programmes d'ordinateur pour détecter et quantifier la quantité d'un androgène 11-oxo dans un échantillon.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962834738P | 2019-04-16 | 2019-04-16 | |
| US62/834,738 | 2019-04-16 | ||
| PCT/US2020/028513 WO2020214811A1 (fr) | 2019-04-16 | 2020-04-16 | Méthodes et systèmes pour la détection d'androgènes 11-oxo par cl-sm/sm |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3134234A1 true CA3134234A1 (fr) | 2020-10-22 |
Family
ID=70680586
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3134234A Pending CA3134234A1 (fr) | 2019-04-16 | 2020-04-16 | Methodes et systemes pour la detection d'androgenes 11-oxo par cl-sm/sm |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US11536733B2 (fr) |
| EP (1) | EP3956669A1 (fr) |
| JP (1) | JP2022528979A (fr) |
| CN (1) | CN113711030A (fr) |
| CA (1) | CA3134234A1 (fr) |
| WO (1) | WO2020214811A1 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3134234A1 (fr) * | 2019-04-16 | 2020-10-22 | Laboratory Corporation Of America Holdings | Methodes et systemes pour la detection d'androgenes 11-oxo par cl-sm/sm |
| WO2022129119A2 (fr) * | 2020-12-17 | 2022-06-23 | F. Hoffmann-La Roche Ag | Procédé lc-ms de détection et de quantification de stéroïdes 11-oxygénés |
| CN114965786B (zh) * | 2022-06-07 | 2023-11-03 | 重庆医科大学附属儿童医院 | 一种检测干血斑中酯类胆固醇多种中间代谢产物的方法 |
| CN116543905B (zh) * | 2023-05-09 | 2024-08-06 | 北京大学第三医院（北京大学第三临床医学院） | 预测卵巢多囊样改变(pcom)的系统和方法 |
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| US5772874A (en) | 1995-11-02 | 1998-06-30 | Cohesive Technologies, Inc. | High performance liquid chromatography method and apparatus |
| PL327920A1 (en) | 1996-01-19 | 1999-01-04 | Cohesive Technologies | Highly efficient liquid chromatography process and chromatographic apparatus therefor |
| GB9717926D0 (en) | 1997-08-22 | 1997-10-29 | Micromass Ltd | Methods and apparatus for tandem mass spectrometry |
| US20110306080A1 (en) * | 2001-11-05 | 2011-12-15 | Quest Diagnostics Investments Incorporated | Determination of lamotrigine by mass spectrometry |
| US7745226B2 (en) * | 2005-04-06 | 2010-06-29 | Quest Diagnostics Investments Incorporated | Methods for detecting vitamin D metabolites |
| US7935921B2 (en) * | 2006-05-26 | 2011-05-03 | Laboratory Corporation Of America Holdings | Methods and systems for the quantitative analysis of biomarkers |
| US20090134325A1 (en) * | 2007-11-27 | 2009-05-28 | Goldman Mildred M | Methods for detecting estradiol by mass spectrometry |
| US7893399B2 (en) * | 2008-09-09 | 2011-02-22 | Quest Diagnostics Investments Incorporated | Methods for detecting dehydroepiandrosterone by mass spectrometry |
| US7804063B2 (en) * | 2008-10-06 | 2010-09-28 | Quest Diagnostics Investments Incorporated | Methods for detecting dihydrotestosterone by mass spectrometry |
| US20100155594A1 (en) * | 2008-12-23 | 2010-06-24 | Goldman Mildred M | Mass spectrometry assay for estrogenic compounds |
| US9146219B2 (en) * | 2014-01-27 | 2015-09-29 | National Medical Services, Inc. | Sensitive method for measuring cis-diol containing compounds in plasma using 2D-LC-MS/MS |
| US20160349221A1 (en) * | 2015-05-27 | 2016-12-01 | Quest Diagnostics Investments Llc | Methods for mass spectrometric quantitation of analytes extracted from a microsampling device |
| CA3134234A1 (fr) * | 2019-04-16 | 2020-10-22 | Laboratory Corporation Of America Holdings | Methodes et systemes pour la detection d'androgenes 11-oxo par cl-sm/sm |
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2020
- 2020-04-16 CA CA3134234A patent/CA3134234A1/fr active Pending
- 2020-04-16 US US16/850,786 patent/US11536733B2/en active Active
- 2020-04-16 WO PCT/US2020/028513 patent/WO2020214811A1/fr unknown
- 2020-04-16 EP EP20725273.5A patent/EP3956669A1/fr active Pending
- 2020-04-16 CN CN202080029045.5A patent/CN113711030A/zh active Pending
- 2020-04-16 JP JP2021560857A patent/JP2022528979A/ja not_active Withdrawn
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| JP2022528979A (ja) | 2022-06-16 |
| US11536733B2 (en) | 2022-12-27 |
| US20200333361A1 (en) | 2020-10-22 |
| CN113711030A (zh) | 2021-11-26 |
| EP3956669A1 (fr) | 2022-02-23 |
| WO2020214811A1 (fr) | 2020-10-22 |
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