CA2661567C - Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant - Google Patents

Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant Download PDF

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Publication number: CA2661567C
Authority: CA; Canada
Prior art keywords: cndot; microparticles; fwdarw; pharmaceutical formulation; cations
Prior art date: 2006-07-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

CA2661567A

Other languages

English (en)

French (fr)

Other versions

CA2661567A1 (fr

Inventor

Alain Constancis

You-Ping Chan

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Flamel Ireland Ltd

Original Assignee

Flamel Ireland Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-07-28

Filing date

2007-07-30

Publication date

2016-09-20

2007-07-30 Application filed by Flamel Ireland Ltd filed Critical Flamel Ireland Ltd

2008-03-06 Publication of CA2661567A1 publication Critical patent/CA2661567A1/fr

2016-09-20 Application granted granted Critical

2016-09-20 Publication of CA2661567C publication Critical patent/CA2661567C/fr

Status Active legal-status Critical Current

2027-07-30 Anticipated expiration legal-status Critical

Links

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238000000889 atomisation Methods 0.000 claims abstract description 67
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238000000034 method Methods 0.000 claims abstract description 39
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DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 7
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
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General Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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Pulmonology (AREA)
Gastroenterology & Hepatology (AREA)
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CA2661567A 2006-07-28 2007-07-30 Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant Active CA2661567C (fr)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR0653191A FR2904219B1 (fr)	2006-07-28	2006-07-28	Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant
FR0653191		2006-08-28
PCT/EP2007/006722 WO2008025425A1 (fr)	2006-07-28	2007-07-30	Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant

Publications (2)

Publication Number	Publication Date
CA2661567A1 CA2661567A1 (fr)	2008-03-06
CA2661567C true CA2661567C (fr)	2016-09-20

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Application Number	Title	Priority Date	Filing Date
CA2661567A Active CA2661567C (fr)	2006-07-28	2007-07-30	Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant

Country Status (11)

Country	Link
EP (1)	EP2049085A1 (ja)
JP (1)	JP5302197B2 (ja)
KR (1)	KR101407033B1 (ja)
CN (1)	CN101568328B (ja)
BR (1)	BRPI0714943A2 (ja)
CA (1)	CA2661567C (ja)
FR (1)	FR2904219B1 (ja)
IL (1)	IL196426A (ja)
MX (1)	MX2009000951A (ja)
WO (1)	WO2008025425A1 (ja)
ZA (1)	ZA200900929B (ja)

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FR2934161B1 (fr) *	2008-07-28	2010-09-17	Flamel Tech Sa	Forme orale microparticulaire utile pour la liberation modifiee de nanoparticules.
FR2940619B1 (fr) *	2008-12-31	2012-02-10	Flamel Technologies Sa	Composition comprenant un actif de solubilite aqueuse faible ou moyenne
FR2954325B1 (fr)	2009-12-23	2012-02-03	Flamel Tech Sa	Polymere amphiphile fonctionnalise par la methionine
JP4829351B2 (ja) *	2010-02-05	2011-12-07	ナノキャリア株式会社	易崩壊型ポリマーミセル組成物
CN102232932B (zh) *	2010-04-27	2013-06-05	重庆莱美药业股份有限公司	果胶-阿霉素轭合物的冻干制剂及制备方法
CN102657843A (zh) *	2012-06-05	2012-09-12	云南民族大学	抗菌肽组合物及其制备方法
CN103483583B (zh) *	2013-09-24	2015-11-18	昆明理工大学	一种ε-聚赖氨酸的制备方法
EP3125931A4 (en)	2014-04-03	2017-09-20	Biondvax Pharmaceuticals Ltd.	Compositions of multimeric-multiepitope influenza polypeptides and their production
ES2841933T3 (es)	2014-10-31	2021-07-12	Univ Monash	Formulación en polvo
KR101891715B1 (ko) *	2016-01-15	2018-08-27	연세대학교 산학협력단	바이러스 감염의 치료용 폴리아미노산 기반의 생체환경 감응형 나노입자
CN109642024A (zh) *	2016-08-02	2019-04-16	日本化药株式会社	主动靶向型高分子衍生物、包含该高分子衍生物的组合物以及它们的用途
CN110483785B (zh) *	2019-07-01	2020-05-19	中山大学	一种三嵌段聚合物、载药纳米胶束、纳米药物及其制备方法和应用
CN110343245B (zh) *	2019-07-16	2021-09-28	天津大学	一种ε-聚赖氨酸-接枝-疏水氨基酸-接枝-海藻糖的糖肽及制备方法
CN112553759A (zh) *	2020-11-30	2021-03-26	福建凤竹纺织科技股份有限公司	一种多功能海藻纤维针织面料

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DE4002736A1 (de) *	1990-01-31	1991-08-01	Hoechst Ag	Biologisch abbaubare polymere, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
US5250293A (en) *	1991-04-22	1993-10-05	Gleich Gerald J	Method for the treatment of hypersensitivity diseases by administration of anionic polymers
GB9221329D0 (en) *	1992-10-10	1992-11-25	Delta Biotechnology Ltd	Preparation of further diagnostic agents
DE4407898A1 (de) *	1994-03-09	1995-09-14	Hoechst Ag	Nanopartikel, enthaltend einen Wirkstoff und ein Polyketalweinsäureamid, Verfahren zu ihrer Herstellung und Verwendung derselben
CN1142772C (zh) *	1999-01-18	2004-03-24	株式会社Lg化学	含有蛋白质药物或抗原的亲脂性微粒以及包含该微粒的制剂
FR2814951B1 (fr) *	2000-10-06	2003-01-17	Flamel Tech Sa	Suspension colloidale de particules submicroniques de vectorisation de principes actifs hydrophiles (insuline) et leur mode de preparation
AU2002335046A1 (en) *	2001-10-19	2003-05-06	Inhale Therapeutic Systems, Inc.	The use of proton sequestering agents in drug formulations
FR2862535B1 (fr) *	2003-11-21	2007-11-23	Flamel Tech Sa	Formulations pharmaceutiques pour la liberation prolongee d'interleukines et leurs applications therapeutiques
FR2862536B1 (fr) *	2003-11-21	2007-11-23	Flamel Tech Sa	Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
FR2862541B1 (fr) *	2003-11-21	2007-04-20	Flamel Tech Sa	Formulations pharmaceutiques pour la liberation prolongee d'interferons et leurs applications therapeutiques

2006
- 2006-07-28 FR FR0653191A patent/FR2904219B1/fr not_active Expired - Fee Related
2007
- 2007-07-30 KR KR1020097004345A patent/KR101407033B1/ko not_active Expired - Fee Related
- 2007-07-30 WO PCT/EP2007/006722 patent/WO2008025425A1/fr active Application Filing
- 2007-07-30 BR BRPI0714943-3A patent/BRPI0714943A2/pt not_active IP Right Cessation
- 2007-07-30 EP EP07801468A patent/EP2049085A1/fr not_active Withdrawn
- 2007-07-30 CN CN2007800318934A patent/CN101568328B/zh not_active Expired - Fee Related
- 2007-07-30 JP JP2009525938A patent/JP5302197B2/ja not_active Expired - Fee Related
- 2007-07-30 CA CA2661567A patent/CA2661567C/fr active Active
- 2007-07-30 ZA ZA200900929A patent/ZA200900929B/xx unknown
- 2007-07-30 MX MX2009000951A patent/MX2009000951A/es active IP Right Grant
2009
- 2009-01-11 IL IL196426A patent/IL196426A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO2008025425A1 (fr)	2008-03-06
IL196426A (en)	2014-07-31
WO2008025425A8 (fr)	2009-04-16
JP5302197B2 (ja)	2013-10-02
KR101407033B1 (ko)	2014-06-20
CA2661567A1 (fr)	2008-03-06
FR2904219B1 (fr)	2010-08-13
CN101568328B (zh)	2012-09-05
FR2904219A1 (fr)	2008-02-01
IL196426A0 (en)	2009-09-22
WO2008025425A9 (fr)	2008-06-12
ZA200900929B (en)	2010-06-30
BRPI0714943A2 (pt)	2013-05-21
WO2008025425B1 (fr)	2008-05-02
JP2009544759A (ja)	2009-12-17
CN101568328A (zh)	2009-10-28
KR20090054976A (ko)	2009-06-01
EP2049085A1 (fr)	2009-04-22
MX2009000951A (es)	2009-02-04
AU2007291577A1 (en)	2008-03-06

Publication	Publication Date	Title
CA2661567C (fr)	2016-09-20	Microparticules a base de copolymere amphiphile et de principe(s) actif(s) a liberation modifiee et formulations pharmaceutiques en contenant
CA2653537C (fr)	2014-07-29	Formulations pharmaceutiques pour la liberation prolongee de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
US20080102128A1 (en)	2008-05-01	Modified-release microparticles based on amphiphilic copolymer and on active principles(s) and pharmaceutical formulations comprising them
USRE46686E1 (en)	2018-01-30	Pharmaceutical formulations for the prolonged release of active principle(s), and their applications, especially therapeutic applications
AU2006221448B2 (en)	2012-03-15	Microparticle and pharmaceutical composition
WO2005051416A1 (fr)	2005-06-09	Formulations pharmaceutiques pour la libération prolongée de principe(s) actif(s), ainsi que leurs applications notamment therapeutiques
WO2008135562A1 (fr)	2008-11-13	Formulations pharmaceutiques auto-precipitantes pour la liberation modifiee de principe actif
EP1511471B1 (fr)	2011-02-02	Suspension colloidale de particules submicronique de vectorisation de principes actifs et leur mode de preparation
EP2155173A1 (fr)	2010-02-24	Particules a base de polyelectrolytes et de principe actif a liberation modifiee et formulations pharmaceutiques contenant ces particules
CA2562495C (fr)	2015-10-20	Utilisation de dipalmitostearate de glycerol pour ameliorer la biodisponibilite de principes actifs proteiques en formulations injectables sous-cutanees ou intramusculaires

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