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CA2325045A1 - Compositions solides contenant des derives de l'acide gamma-aminobutyrique, et procede de preparation associe - Google Patents

Compositions solides contenant des derives de l'acide gamma-aminobutyrique, et procede de preparation associe Download PDF

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Publication number
CA2325045A1
CA2325045A1 CA002325045A CA2325045A CA2325045A1 CA 2325045 A1 CA2325045 A1 CA 2325045A1 CA 002325045 A CA002325045 A CA 002325045A CA 2325045 A CA2325045 A CA 2325045A CA 2325045 A1 CA2325045 A1 CA 2325045A1
Authority
CA
Canada
Prior art keywords
gamma
preparing
same
acid derivatives
aminobutyric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002325045A
Other languages
English (en)
Other versions
CA2325045C (fr
Inventor
Akira Aomatsu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=15097314&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2325045(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Individual filed Critical Individual
Priority claimed from PCT/US1999/010186 external-priority patent/WO1999059572A1/fr
Publication of CA2325045A1 publication Critical patent/CA2325045A1/fr
Application granted granted Critical
Publication of CA2325045C publication Critical patent/CA2325045C/fr
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/282—Organic compounds, e.g. fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Arrangement Of Transmissions (AREA)
  • Body Structure For Vehicles (AREA)
CA002325045A 1998-05-15 1999-05-10 Compositions solides contenant des derives de l'acide gamma-aminobutyrique, et procede de preparation associe Expired - Lifetime CA2325045C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13312298A JP3761324B2 (ja) 1998-05-15 1998-05-15 乗用田植機
JP10/133112 1998-05-15
PCT/US1999/010186 WO1999059572A1 (fr) 1998-05-15 1999-05-10 Compositions solides contenant des derives de l'acide gamma-aminobutyrique, et procede de preparation associe

Publications (2)

Publication Number Publication Date
CA2325045A1 true CA2325045A1 (fr) 1999-11-25
CA2325045C CA2325045C (fr) 2005-05-03

Family

ID=15097314

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002325045A Expired - Lifetime CA2325045C (fr) 1998-05-15 1999-05-10 Compositions solides contenant des derives de l'acide gamma-aminobutyrique, et procede de preparation associe

Country Status (16)

Country Link
JP (1) JP3761324B2 (fr)
CN (1) CN1171587C (fr)
AT (1) ATE407668T1 (fr)
CA (1) CA2325045C (fr)
CY (1) CY1108488T1 (fr)
DE (1) DE69939532D1 (fr)
DK (1) DK1077691T3 (fr)
EA (1) EA006553B1 (fr)
EE (1) EE05530B1 (fr)
EG (1) EG26287A (fr)
ES (1) ES2312208T3 (fr)
GE (1) GEP20032987B (fr)
IL (2) IL139202A0 (fr)
NZ (1) NZ507162A (fr)
PT (1) PT1077691E (fr)
UA (1) UA76398C2 (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4904636B2 (ja) * 2001-05-29 2012-03-28 井関農機株式会社 トラクタフレーム
JP5047022B2 (ja) * 2008-03-24 2012-10-10 ヤンマー株式会社 上下分割式のエンジン収納用パッケージの結合構造
WO2013008182A1 (fr) * 2011-07-10 2013-01-17 Mahesh Kandula Précurseurs d'analogues de l'acide γ-aminobutyrique (gaba)
US9303038B2 (en) 2011-09-06 2016-04-05 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological diseases
US9399634B2 (en) 2012-05-07 2016-07-26 Cellix Bio Private Limited Compositions and methods for the treatment of depression
CN104603096A (zh) 2012-05-07 2015-05-06 塞利克斯比奥私人有限公司 用于治疗神经肌肉障碍和神经退行性疾病的组合物和方法
CA2872975A1 (fr) 2012-05-07 2013-11-14 Cellixbio Private Limited Compositions et methodes de traitement de troubles neurologiques
WO2013168019A1 (fr) * 2012-05-07 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur neuropathique
WO2013167991A1 (fr) 2012-05-08 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de troubles métaboliques
WO2013168025A1 (fr) 2012-05-08 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement des maladies de coagulation du sang
US9434704B2 (en) 2012-05-08 2016-09-06 Cellix Bio Private Limited Compositions and methods for the treatment of neurological degenerative disorders
WO2013167992A1 (fr) 2012-05-08 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de troubles inflammatoires
US9266823B2 (en) 2012-05-08 2016-02-23 Cellix Bio Private Limited Compositions and methods for the treatment of parkinson's disease
US20150087674A1 (en) * 2012-05-10 2015-03-26 Mahesh Kandula Compositions and methods for the treatment of severe pain
WO2013168005A2 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement du syndrome des jambes sans repos et de la fibromyalgie
WO2013168015A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes pour le traitement de l'asthme et de l'allergie
WO2013168000A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur sévère
US9499527B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of familial amyloid polyneuropathy
US9499526B2 (en) 2012-05-10 2016-11-22 Cellix Bio Private Limited Compositions and methods for the treatment of neurologic diseases
WO2013168001A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur modérée à sévère
SG11201407318UA (en) 2012-05-10 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of metabolic syndrome
US9315478B2 (en) 2012-05-10 2016-04-19 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
WO2013168011A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de la douleur chronique
US9346742B2 (en) 2012-05-10 2016-05-24 Cellix Bio Private Limited Compositions and methods for the treatment of fibromyalgia pain
WO2013167999A2 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement d'affections neurologiques
WO2013168012A1 (fr) 2012-05-10 2013-11-14 Mahesh Kandula Compositions et méthodes de traitement de troubles respiratoires
US9233161B2 (en) 2012-05-10 2016-01-12 Cellix Bio Private Limited Compositions and methods for the treatment of neurological conditions
CN104603100A (zh) 2012-05-23 2015-05-06 塞利克斯比奥私人有限公司 用于治疗炎症性肠病的组合物和方法
EP2852571A4 (fr) 2012-05-23 2015-11-25 Cellix Bio Private Ltd Compositions et méthodes pour le traitement de la mucosite
WO2013175376A2 (fr) 2012-05-23 2013-11-28 Mahesh Kandula Compositions et méthodes de traitement de la douleur locale
JP2015518854A (ja) 2012-05-23 2015-07-06 セリックスビオ プライヴェート リミテッド 多発性硬化症の治療のための組成物および方法
US9227974B2 (en) 2012-05-23 2016-01-05 Cellex Bio Private Limited Compositions and methods for the treatment of respiratory disorders
WO2013175344A2 (fr) 2012-05-23 2013-11-28 Mahesh Kandula Compositions et méthodes pour le traitement de la parodontite et de la polyarthrite rhumatoïde
US9108942B1 (en) 2014-11-05 2015-08-18 Mahesh Kandula Compositions and methods for the treatment of moderate to severe pain
WO2014020480A2 (fr) 2012-08-03 2014-02-06 Mahesh Kandula Compositions et méthodes pour le traitement de la migraine et de maladies neurologiques
WO2014037833A2 (fr) 2012-09-06 2014-03-13 Mahesh Kandula Compositions et méthodes de traitement d'une inflammation et de troubles lipidiques
CA2873029A1 (fr) 2012-09-08 2014-03-13 Cellixbio Private Limited Compositions et methodes de traitement d'une inflammation et de troubles lipidiques
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
EP3004049B1 (fr) 2013-06-04 2018-09-05 Cellixbio Private Limited Compositions et procédés de traitement du diabète et du pré-diabète
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
CA2976314C (fr) 2014-09-26 2021-02-23 Cellix Bio Private Limited Compositions et methodes de traitement de l'epilepsie et de troubles neurologiques
SG11201702554QA (en) 2014-09-29 2017-04-27 Cellix Bio Private Ltd Compositions and methods for the treatment of multiple sclerosis
CN104352476A (zh) * 2014-10-21 2015-02-18 齐宏 一种加巴喷丁胶囊及其制备方法
CA2965449C (fr) 2014-10-27 2020-11-10 Cellix Bio Private Limited Sels ternaires d'ester monomethylique d'acide fumarique associes a la piperazine ou a l'ethylenediamine pour le traitement de la sclerose en plaques
US9150557B1 (en) 2014-11-05 2015-10-06 Cellix Bio Private Limited Compositions and methods for the treatment of hyperglycemia
US9173877B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Compositions and methods for the treatment of local pain
US9284287B1 (en) 2014-11-05 2016-03-15 Cellix Bio Private Limited Compositions and methods for the suppression of carbonic anhydrase activity
US10208014B2 (en) 2014-11-05 2019-02-19 Cellix Bio Private Limited Compositions and methods for the treatment of neurological disorders
US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
US9175008B1 (en) 2014-11-05 2015-11-03 Cellix Bio Private Limited Prodrugs of anti-platelet agents
US9290486B1 (en) 2014-11-05 2016-03-22 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
CN107428697A (zh) 2015-01-06 2017-12-01 塞尔利克斯生物私人有限公司 用于治疗炎症和疼痛的组合物和方法

Also Published As

Publication number Publication date
ATE407668T1 (de) 2008-09-15
JPH11318133A (ja) 1999-11-24
EA200001154A1 (ru) 2001-06-25
EA006553B1 (ru) 2006-02-24
DE69939532D1 (de) 2008-10-23
DK1077691T3 (da) 2008-10-27
PT1077691E (pt) 2008-11-04
IL139202A (en) 2014-12-31
CA2325045C (fr) 2005-05-03
ES2312208T3 (es) 2009-02-16
EE200000671A (et) 2002-04-15
GEP20032987B (en) 2003-06-25
CN1300213A (zh) 2001-06-20
JP3761324B2 (ja) 2006-03-29
EE05530B1 (et) 2012-04-16
IL139202A0 (en) 2001-11-25
NZ507162A (en) 2003-11-28
CY1108488T1 (el) 2014-04-09
UA76398C2 (en) 2006-08-15
EG26287A (en) 2013-06-12
CN1171587C (zh) 2004-10-20

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Effective date: 20190510